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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Neurodegenerative Diseases: Recent Advances and Future Perspectives, 2nd Edition

edited by

Inés López-Cuenca

and

Rosa De Hoz

submission deadline 25 Jun 2026 | 2 articles | Viewed by 8338 | Submission Open

Keywords: neurodegeneration; neuroprotection; dementia; Parkinson’ s disease

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Neutrophils in Immunity and Diseases: 2nd Edition

edited by

Akrivi Chrysanthopoulou

submission deadline 29 Jun 2026 | Viewed by 440 | Submission Open

Keywords: neutrophils; inflammation; neutrophil biology; immunity; NETs

(This special issue belongs to the Section Cell Biology and Pathology)

Molecular Mechanism in Inflammation and Immunity: 2nd Edition

edited by Anella Saviano

submission deadline 29 Jun 2026 | Viewed by 328 | Submission Open

Keywords: adaptive immunity; autoimmune-based diseases; cyto/chemokines; inflammation; macrophages; natural compounds; nutraceuticals; signaling pathway in arachidonic acid cascade; T-cells; trained immunity

(This special issue belongs to the Section Immunology and Immunotherapy)

Progress in Neurodevelopmental Disorders Research

edited by

Catarina Morais Seabra

submission deadline 30 Jun 2026 | 6 articles | Viewed by 51276 | Submission Open

Keywords: neurodevelopmental disorders; autism spectrum disorder; attention deficit hyperactivity disorder

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Feature Reviews on Cardiovascular and Metabolic Diseases

edited by

Cristiana Bustea

submission deadline 30 Jun 2026 | 5 articles | Viewed by 27634 | Submission Open

Keywords: cardiovascular diseases; metabolic diseases; global health; disease prevention; innovative treatments

(This special issue belongs to the Section Cell Biology and Pathology)

Dualistic Equilibrium in Neurotransmission and Beyond: Unraveling the Pathophysiology and Unlocking Novel Therapeutic Targets in Neuropsychiatric Disorders—2nd Edition

edited by

Masaru Tanaka

and

Simone Battaglia

submission deadline 30 Jun 2026 | 2 articles | Viewed by 14921 | Submission Open

Keywords: Alzheimer’ s disease; Parkinson’ s disease; cognitive dysfunction; multiple sclerosis; stroke; migraine; chronic pain; depressive disorder; bipolar disorder; post-traumatic stress disorder; anxiety disorder; schizophrenia; somatic symptom disorder; autism spectrum disorder; hyperactive attention deficit disorder; learning disabilities; brain injuries; comorbidity; brain plasticity; transcranial magnetic stimulation (TMS); transcranial direct current stimulation (tDCS)

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Renin-Angiotensin System in Cardiovascular Biology, 2nd Edition

edited by

Mária Szekeres

György L. Nádasy

and

László Dézsi

submission deadline 30 Jun 2026 | 7 articles | Viewed by 14861 | Submission Open

Keywords: renin– angiotensin system (RAS); signaling mechanisms of angiotensin receptors; GPCR; AT1R; AT2R; ACE; ACE2; ACEI; angiotensin II; signal transduction; cardiovascular system; hypertension; atherosclerosis; heart failure; cardiovascular remodeling; osmoregulation; inflammation

(This special issue belongs to the Section Molecular and Translational Medicine)

New Insights in Hematologic Malignancies: From Pathophysiologic Mechanisms to Therapeutic Strategies

edited by

Yun Chen

submission deadline 30 Jun 2026 | 7 articles | Viewed by 14151 | Submission Open

Keywords: leukemia; hematological malignancies; tumor microenvironment; disease models; precision medicine; immunotherapy; targeted therapy; drug resistance; biomarkers; translational research

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Brain Tumor Diagnosis: Innovations and Emerging Technologies

edited by

Mubarak Taiwo Mustapha

submission deadline 30 Jun 2026 | 5 articles | Viewed by 13186 | Submission Open

Keywords: brain tumor diagnosis; artificial intelligence in oncology; deep learning in medical imaging; machine learning models; predictive analytics in healthcare; digital pathology; glioma detection; multi-modal data integration; neuro-oncology; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

The Role of Telomere and Telomerase in Human Disease—2nd Edition

edited by

Orit Uziel

submission deadline 30 Jun 2026 | 7 articles | Viewed by 10964 | Submission Open

Keywords: telomere; telomerase; cancer; aging

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Novel Drug Discovery, Synthesis, and Evaluation

edited by

Khaled M. Elokely

submission deadline 30 Jun 2026 | 4 articles | Viewed by 9971 | Submission Open

Keywords: drug synthesis; novel therapies; disease targets; medicinal chemistry; computational methods; screening techniques; pharmaceutical development; target identification

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Molecular Mechanisms and Translational Research on Insulin Resistance

edited by

Terisha Ghazi

submission deadline 30 Jun 2026 | 2 articles | Viewed by 9462 | Submission Open

Keywords: insulin resistance; type 2 diabetes mellitus; metabolic syndrome; insulin signaling; inflammation; oxidative stress; mitochondrial dysfunction; epigenetics; epitranscriptomics (e.g.; m6A RNA methylation); biomarkers; translational medicine; therapeutic targets

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Prostate Cancer Targeted Therapy: Highlighting Advances in Precision Medicine and Rational Combination Approaches

edited by Alan P. Lombard

submission deadline 30 Jun 2026 | 5 articles | Viewed by 9317 | Submission Open

Keywords: prostate cancer; precision medicine; targeted therapeutics; rational drug combinations; clinical biomarkers

(This special issue belongs to the Section Cancer Biology and Oncology)

New Advances in Ovarian Cancer

edited by

Zhenshan Yang

and

Hengrui Liu

submission deadline 30 Jun 2026 | 6 articles | Viewed by 9009 | Submission Open

Keywords: ovarian cancer; biomarkers; cell biology; gene regulation; target therapy; therapeutic resistance; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

Coronary Artery Disease: From Pathophysiology to Therapeutic Strategies

edited by

Pawel Nadziakiewicz

submission deadline 30 Jun 2026 | 4 articles | Viewed by 8349 | Submission Open

Keywords: pathophysiological concept of coronary artery disease; coronary microvascular dysfunction; chronic coronary syndrome; acute coronary syndrome; post-acute coronary syndrome with heart failure; diagnostics in coronary artery disease; therapeutic strategies in CAD; revascularization

(This special issue belongs to the Section Cell Biology and Pathology)

Sphingolipid Metabolism and Signaling in Health and Diseases: 2nd Edition

edited by

Giulia Lunghi

Elena Chiricozzi

and

Maria Fazzari

submission deadline 30 Jun 2026 | 3 articles | Viewed by 8001 | Submission Open

Keywords: sphingolipids; glycosphingolipids; gangliosides; sphingosine-1-phosphate; cell homeostasis; neurodegeneration; neurodevelopment; inflammation; diabetes; cystic fibrosis; cancer

(This special issue belongs to the Section Cell Biology and Pathology)

Diagnostic and Therapeutic Challenges of CAR-T Cell Therapy

edited by Vincenzo Maria Perriello

submission deadline 30 Jun 2026 | 2 articles | Viewed by 7325 | Submission Open

Keywords: CAR-T therapy; immunotherapy; relapsed/refractory diffuse large B cell lymphoma (r/r DLBCL); relapsed/refractory mantle cell lymphoma (r/r MCL); B-acute lymphoblastic leukemia (r/r B-ALL); bridging therapy; cytokine release syndrome (CRS); immune effector cell associated neurotoxicity (ICANS); biomarkers; PET/CT assessment after CAR-T cell therapy

(This special issue belongs to the Section Gene and Cell Therapy)

New Insights in Radiotherapy: Bridging Radiobiology and Oncology

edited by

Chris Y. Lee

and I-Tsang Chiang

submission deadline 30 Jun 2026 | 4 articles | Viewed by 7181 | Submission Open

Keywords: tissue-sparing effect; bystander effect; factors that affect radiation-induced lethality; radiation-induced abscopal effect; mechanisms that enhance tissue radiosensitivity; synergistic effect from radiotherapy and immunotherapy; regulatory perspectives on medical radiation safety

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Type 2 Diabetes: Insulin Regulation and Therapeutic Strategies

edited by

Syed A. A. Rizvi

submission deadline 30 Jun 2026 | 4 articles | Viewed by 6395 | Submission Open

Keywords: type 2 diabetes; insulin regulation; glycemic control; insulin resistance; therapeutic strategies; personalized medicine; GLP-1 receptor agonists; SGLT2 inhibitors; novel insulin formulations; non-insulin therapies

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Two Decades of Advances in Colorectal Cancer Prevention and Treatment: From Aspirin to Precision Oncology

edited by

Manish Tripathi

and

Puneet Vij

submission deadline 30 Jun 2026 | 2 articles | Viewed by 6387 | Submission Open

Keywords: immunotherapy; biomarkers; colorectal cancer; targeted therapies; molecular pathways

(This special issue belongs to the Section Cancer Biology and Oncology)

Pancreatic, Liver, Biliary Tract and Intestinal Diseases: Pathogenesis, Diagnostics and Therapy—2nd Edition

edited by

Beata Jabłońska

and

Sławomir Mrowiec

submission deadline 30 Jun 2026 | 3 articles | Viewed by 6352 | Submission Open

Keywords: inflammatory bowel disease; gastrointestinal tumor; gastrointestinal cancer; acute pancreatitis; chronic pancreatitis; pancreatic cyst; biliary cyst; liver disease; biliary tract disease

(This special issue belongs to the Section Molecular and Translational Medicine)

Coronary Artery Disease: Current Evidence and Future Perspectives

edited by Tadateru Takayama

submission deadline 30 Jun 2026 | 4 articles | Viewed by 6001 | Submission Open

Keywords: coronary artery disease; lipid-lowering therapy; residual risk; small dense LDL; lipoprotein(a); endothelial dysfunction; oxidative stress; inflammation; biomarkers; cardiovascular prevention

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Pharmacology of Pain and Inflammation

edited by Fernanda Regina de Castro Almeida and Francisco De Assis Oliveira

submission deadline 30 Jun 2026 | 2 articles | Viewed by 5566 | Submission Open

Keywords: natural products; chronic pain; neuropathies; oncological pain; anti-inﬂammatory activity; pulmonary emphysema

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Oxidative Stress and Inflammation: From Mechanisms to Therapeutic Approaches (4th Edition)

edited by

Juan Gambini

submission deadline 30 Jun 2026 | 2 articles | Viewed by 5155 | Submission Open

Keywords: oxidative stress; inflammation; molecular mechanisms; pharmacotherapy; longevity; aging

(This special issue belongs to the Section Immunology and Immunotherapy)

Inflammation in Neurogenerative Diseases: Mechanisms and Therapeutic Frontiers

edited by

Shao-Bin Wang

submission deadline 30 Jun 2026 | 2 articles | Viewed by 4899 | Submission Open

Keywords: neuroinflammation; neurodegenerative diseases; biomarkers mitochondria dysfunction; microglia; immune response; therapeutic development; gene therapy

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Urogenital Cancers: New Molecular and Translational Aspects on Carcinogenesis and Treatments (2nd Edition)

edited by

Silvia Di Agostino

Vittoria Rago

and

Anna Perri

submission deadline 30 Jun 2026 | 3 articles | Viewed by 4371 | Submission Open

Keywords: prostate cancer; bladder cancer; renal cell carcinoma; testicular cancer; ovarian cancer; endometrial cancer; carcinogenesis; biomarkers; early diagnosis; upper urinary tract tumors; diagnosis; treatment; environmental factors; diet

(This special issue belongs to the Section Cancer Biology and Oncology)

Inherited Retinal Diseases: From Pathomolecular Mechanisms to Therapeutic Strategies, 2nd Edition

edited by

José Martín-Nieto

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3926 | Submission Open

Keywords: blindness; gene and protein function; pathogenesis; personalized diagnosis; precision therapy; retina; retinal degeneration

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular and Histopathological Background of Diabetic Neuropathy

edited by

Mária Bagyánszki

submission deadline 30 Jun 2026 | 4 articles | Viewed by 3903 | Submission Open

Keywords: diabetic neuropathy; insulin; hyperglycaemia; peripheral neuropathy; autonomic neuropathy; proximal neuropathy; enteric neuropathy; mononeuropathy

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances in the Pathogenesis and Treatment of Acute Myeloid Leukemia—2nd Edition

edited by

Alessandra Sperotto

submission deadline 30 Jun 2026 | 1 articles | Viewed by 3696 | Submission Open

Keywords: acute myeloid leukemia; target therapies; molecular pathogenesis; biological therapy; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

An Update on Mechanisms and Treatments for Thyroid Cancer in Current Oncology, 2nd Edition

edited by Zhilong Ai

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3684 | Submission Open

Keywords: thyroid cancer; mechanisms; treatments; biomarkers; precision medicine; infiltration; metastasis

(This special issue belongs to the Section Cancer Biology and Oncology)

New Challenges in the Study of Liver Diseases: From Molecular Pathogenesis to Therapeutic Approaches—4th Edition

edited by

Marica Meroni

submission deadline 30 Jun 2026 | 3 articles | Viewed by 3580 | Submission Open

Keywords: liver diseases and related pathologies; non-alcoholic fatty liver diseases (NAFLDs); obesity; type 2 diabetes; cardiovascular diseases; gut– liver axis; viral hepatitis; alcoholic liver diseases (ALDs); cholestatic disorders; personalized medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Updates on Kawasaki Disease

edited by Eisuke Suganuma

submission deadline 30 Jun 2026 | 3 articles | Viewed by 3439 | Submission Open

Keywords: coronary artery aneurysm; cluster; individualized treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Antipsychotics: 70 Years—2nd Edition

edited by

Giovanni Lentini

and

Serge Mignani

submission deadline 30 Jun 2026 | 1 articles | Viewed by 3358 | Submission Open

Keywords: polypharmacology; multi-target drugs; emerging therapeutic targets; repurposing; complementary medicine; psychosis; schizophrenia; bipolar disorder; Alzheimer’ s disease

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Pathogenesis, Diagnostics, and Therapeutics for Rheumatic Diseases (2nd Edition)

edited by Jixin Zhong

submission deadline 30 Jun 2026 | 3 articles | Viewed by 3317 | Submission Open

Keywords: rheumatic diseases; pathogenesis; autoimmunity; biomarkers; precision medicine; therapeutics; disease management; immunology; clinical diagnostics; treatment strategies

(This special issue belongs to the Section Molecular and Translational Medicine)

Chronic Heart Failure: From Biomarkers to Targeted Therapies

edited by

Dana Emilia Man

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3088 | Submission Open

Keywords: biomarkers in heart failure; GDMT in heart failure; targeted therapies

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Advances in Parkinson’s Disease Research

edited by

Valentino Racki

submission deadline 30 Jun 2026 | 4 articles | Viewed by 3025 | Submission Open

Keywords: Parkinson’ s disease; movement disorders; neurodegeneration; biomarkers; deep brain stimulation; infusion therapies; gut– brain axis; neuroinflammation; personalized medicine; atypical parkinsonism

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

The Aging Metabolism: Diabetes, Obesity, and Lifespan Insights

edited by

Rafael Ramírez-Carracedo

and

Rafael Moreno-Gómez-Toledano

submission deadline 30 Jun 2026 | 3 articles | Viewed by 2975 | Submission Open

Keywords: metabolic diseases; aging; obesity; diabetes; cell signaling

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Neonatal Disease: From Pathophysiology to Current and Emerging Therapeutic Approaches (3rd Edition)

edited by

Fumihiko Namba

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2873 | Submission Open

Keywords: fetal therapy; neonatal diseases; pathophysiology; innovative therapeutic approaches

(This special issue belongs to the Section Cell Biology and Pathology)

Epilepsy: Pathomechanism, Diagnostics, and Novel Treatment Options

edited by

Monika Rudkowska

and

Karolina Wojtunik-Kulesza

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2855 | Submission Open

Keywords: epilepsy; pathophysiology; neurobiology; molecular pathways; experimental models of epilepsy; neuroinflammation; seizure prediction; biomarker discovery; electrophysiological studies; precision neurology

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances in 3D Bioprinting: From Materials to Functional Tissue Constructs

edited by

Tina Maver

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2819 | Submission Open

Keywords: 3D bioprinting; tissue engineering; biofabrication; regenerative medicine; bioprinted skin; organ-on-a-chip; biomaterials; vascularized constructs

(This special issue belongs to the Section Biomedical Engineering and Materials)

Emerging Therapeutic Strategies for Epilepsy: Bridging Research and Clinical Practice

edited by Tanveer Singh

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2727 | Submission Open

Keywords: epilepsy; status epilepticus; MRI; EEG; inhibitory neurotransmission; immunohistochemistry; gene regulation; neurodegeneration; precision medicine

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Pathogenesis, Diagnosis and Treatment of Cardiomyopathy and Cardiac Arrhythmias (3rd Edition)

edited by Sung Il Im

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2654 | Submission Open

Keywords: arrhythmia; cardiomyopathy; pathogenesis; diagnosis

(This special issue belongs to the Section Molecular and Translational Medicine)

Glioma Therapy: Current Status and Future Prospects

edited by Bernd Kaina

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2640 | Submission Open

Keywords: glioblastoma; temozolomide; nitrosoureas; immunotherapy; biologicals; tyrosine kinase inhibitors; senotherapeutics

(This special issue belongs to the Section Cancer Biology and Oncology)

Current Status and Future Directions of Molecular Genetics and Genetic Diseases

edited by

Darko Katalinić

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2636 | Submission Open

Keywords: molecular genetics; genetic diseases; genetic therapy

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Pathogenesis, Diagnosis and Treatment of Infectious Diseases (2nd Edition)

edited by

Laura Franza

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2629 | Submission Open

Keywords: infection; infectious diseases; vaccination; antibiotics; antibiotic resistance; novel therapies; novel diagnosis; inflammaging; immunosenescence

(This special issue belongs to the Section Molecular and Translational Medicine)

Emerging Molecular and Translational Insights into Obstructive Sleep Apnea and Its Cardiovascular Comorbidities

edited by Hui-Ting Wang and

Yunglung Chen

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2500 | Submission Open

Keywords: obstructive sleep apnea (OSA); atrial fibrillation (AF); molecular mechanisms; epigenetics; biomarkers; oxidative stress; inflammation; endothelial dysfunction; translational research; precision medicine; artificial intelligence; cardiovascular comorbidities

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Role of DNA Methylation in Human Health and Diseases

edited by

Ting-Hai Xu

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2224 | Submission Open

Keywords: DNA methylation; epigenetics; translational research; biomarker; gene regulation; epigenetic therapy

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Cardiac Arrhythmias: Technological Frontiers, Therapeutic Approaches and Future Directions

edited by

Panteleimon Pantelidis

Polychronis E. Dilaveris

, Raffaele De Lucia and

Evangelos Oikonomou

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2004 | Submission Open

Keywords: cardiac arrhythmias; electrophysiology; implantable devices; artificial intelligence; translational medicine; arrhythmogenesis; e-cardiology; biomarkers; telemonitoring

(This special issue belongs to the Section Molecular and Translational Medicine)

Pathogenesis and Novel Diagnostic Techniques in Juvenile Idiopathic Arthritis—Second Edition

edited by

Katarzyna Winsz-Szczotka

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1965 | Submission Open

Keywords: juvenile idiopathic arthritis; pathogenesis; cartilage and bone anabolism and catabolism; diagnostics; treatment; prevention

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Precision Oncology for Thyroid Carcinoma: Integrating Artificial Intelligence, Genomics and Molecular Diagnostics

edited by

Kyoung Sik Park

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1811 | Submission Open

Keywords: thyroid carcinoma; artificial intelligence; genomics; precision oncology; molecular diagnostics

(This special issue belongs to the Section Cancer Biology and Oncology)

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