Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Next-Generation Sequencing and Proteomics Research for Retinal Diseases
edited by Jayshree Advani
submission deadline 16 Feb 2025 | 2 articles | Viewed by 3338
Keywords: genomics; proteomics; biomarker; variant interpretation; single-molecule sequencing; epigenome; retinal degeneration; genetics
(This special issue belongs to the Section Molecular and Translational Medicine)
Dualistic Equilibrium in Neurotransmission and Beyond: Unraveling the Pathophysiology and Unlocking Novel Therapeutic Targets in Neuropsychiatric Disorders submission deadline 28 Feb 2025 | 7 articles | Viewed by 28195 | Submission Open
Keywords: Alzheimer’ s disease; Parkinson’ s disease; cognitive dysfunction; multiple sclerosis; stroke; migraine; chronic pain; depressive disorder; bipolar disorder; post-traumatic stress disorder; anxiety disorder; schizophrenia; somatic symptom disorder; autism spectrum disorder; hyperactive attention deficit disorder; learning disabilities; brain injuries; comorbidity; brain plasticity; transcranial magnetic stimulation (TMS); transcranial direct current stimulation (tDCS)
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Recent Advances in Adipokines—2nd Edition
edited by
submission deadline 28 Feb 2025 | 14 articles | Viewed by 24182 | Submission Open
Keywords: adiponectin; receptor; agonist; biomarker; inflammation; cancer
(This special issue belongs to the Section Cell Biology and Pathology)
Emerging Trends in Neurostimulation and Neuromodulation Research
edited by Mayank Gupta and Brittni Levasseur
submission deadline 28 Feb 2025 | 10 articles | Viewed by 23771 | Submission Open
Keywords: neuromodulation; nerve stimulation; neurostimulation waveforms; chronic pain treatment; pathophysiology
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Omics Approaches on Immune-Mediated Inflammatory Diseases: Towards Novel Biomarkers and Potential Therapeutic Targets Vol. 2 submission deadline 28 Feb 2025 | 6 articles | Viewed by 20084 | Submission Open
Keywords: IMIDs; IBD; Crohn’ s disease; ulcerative colitis; SLE; Sjogren’ s syndrome; rheumatoid arthritis; psoriatic arthritis; multiple sclerosis; bulk and single-cell omics; multi-omics flow cytometry; next-generation microscopy; tissue microarrays; systems biology
(This special issue belongs to the Section Gene and Cell Therapy)
An Update on Mechanisms and Treatments for Thyroid Cancer in Current Oncology
edited by Zhilong Ai
submission deadline 28 Feb 2025 | 9 articles | Viewed by 19310 | Submission Open
Keywords: thyroid cancer; mechanisms; treatments; biomarkers; precision medicine; infiltration; metastasis
(This special issue belongs to the Section Cancer Biology and Oncology)
The Role of Cytokines in Health and Disease: 2nd Edition
edited by
submission deadline 28 Feb 2025 | 10 articles | Viewed by 17887 | Submission Open
Keywords: cytokine; chemokine; neurodegenerative disease; cancer; inflammatory mediator; diagnosis; biomarker
(This special issue belongs to the Section Cell Biology and Pathology)
State-of-the-Art Endocrinology and Metabolism Research in Poland (Volume II)
edited by
submission deadline 28 Feb 2025 | 8 articles | Viewed by 17749 | Submission Open
Keywords: endocrinology; diabetes; obesity; osteoporosis; hyperthyroidism; metabolism; genetic
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Advances in Immunotherapy and Radiation Therapy for Cancer
edited by and Benjamin Spieler
submission deadline 28 Feb 2025 | 9 articles | Viewed by 16266 | Submission Open
Keywords: radiotherapy; immunotherapy; outcome; toxicity; normal tissue; abscopal; tumor; systemic; local; response
(This special issue belongs to the Section Cancer Biology and Oncology)
Sepsis: Pathophysiology and Early Diagnostics
edited by Alexandros Rovas
submission deadline 28 Feb 2025 | 10 articles | Viewed by 14880 | Submission Open
Keywords: biomarkers; infection; organ dysfunction; endothelial dysfunction; organ dysfunction; glycocalyx; cytokine storm; dysregulated immune response
(This special issue belongs to the Section Immunology and Immunotherapy)
Diagnosis, Pathogenesis and Treatment of Muscular Dystrophy
edited by
submission deadline 28 Feb 2025 | 7 articles | Viewed by 12948 | Submission Open
(This special issue belongs to the Section Molecular and Translational Medicine)
Pancreatic, Liver, Biliary Tract and Intestinal Diseases: Pathogenesis, Diagnostics and Therapy submission deadline 28 Feb 2025 | 8 articles | Viewed by 11233 | Submission Open
Keywords: inflammatory bowel disease; gastrointestinal tumor; gastrointestinal cancer; acute pancreatitis; chronic pancreatitis; pancreatic cyst; biliary cyst
(This special issue belongs to the Section Molecular and Translational Medicine)
Cellular and Pathogenesis Mechanisms in Oral Cancer
edited by
submission deadline 28 Feb 2025 | 4 articles | Viewed by 9295 | Submission Open
Keywords: oral carcinogenesis; oral cancer model; OSCC; oral cytology; biomarkers; targeted therapies; precision medicine; bioinformatics
(This special issue belongs to the Section Molecular and Translational Medicine)
Two Decades of Progress in the Prevention and Treatment of Colorectal Cancer: From Aspirin to Targeted Therapy
edited by and
submission deadline 28 Feb 2025 | 4 articles | Viewed by 8573 | Submission Open
Keywords: immunotherapy; biomarkers; colorectal cancer; targeted therapies; molecular pathways; resistance; personalized medicine; genomic profiling; chemoprevention
(This special issue belongs to the Section Cancer Biology and Oncology)
Pathogenesis, Diagnosis and Treatment of Cardiomyopathy and Cardiac Arrhythmias
edited by Sung Il Im
submission deadline 28 Feb 2025 | 5 articles | Viewed by 8525 | Submission Open
Keywords: arrhythmia; cardiomyopathy; pathogenesis; diagnosis
(This special issue belongs to the Section Molecular and Translational Medicine)
Heart Failure: New Diagnostic and Therapeutic Approaches submission deadline 28 Feb 2025 | 6 articles | Viewed by 8379 | Submission Open
Keywords: heart failure; clinical treatment; basic cardiac research; future perspective; heart failure therapy; cardiotoxicity
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced Cancer Diagnosis and Treatment: Second Edition
edited by and Hideshi Ishii
submission deadline 28 Feb 2025 | 7 articles | Viewed by 8315 | Submission Open
Keywords: cancer biology; epigenetics; early detection; diagnosis; biodiagnosis; novel therapeutics; new paradigms
(This special issue belongs to the Section Cancer Biology and Oncology)
Next Generation Cytopathology: Current Status and Future Prospects
edited by
submission deadline 28 Feb 2025 | 3 articles | Viewed by 8212 | Submission Open
Keywords: cytology; diagnosis; digital; effusion; fine needle aspiration; machine learning; molecular; next-generation sequencing; rapid onsite; reporting system
(This special issue belongs to the Section Molecular and Translational Medicine)
Peripheral Artery Disease and Diabetic Foot Ulcer: From Bench to Clinic (2nd Edition) submission deadline 28 Feb 2025 | 5 articles | Viewed by 7740 | Submission Open
Keywords: peripheral artery diseases; diabetic foot ulcer; atherosclerosis; regenerative medicine; inflammatory
(This special issue belongs to the Section Molecular and Translational Medicine)
Pathogenesis and Treatment of Diabetic Cardiomyopathy
edited by
submission deadline 28 Feb 2025 | 3 articles | Viewed by 6882 | Submission Open
Keywords: diabetic cardiomyopathy; molecular mechanisms; risk factors; diagnosis; therapy
(This special issue belongs to the Section Cell Biology and Pathology)
Chronic Pain: From Prevention to Therapeutic Strategies—Second Edition
edited by Isaura Tavares and
submission deadline 28 Feb 2025 | 4 articles | Viewed by 6362 | Submission Open
Keywords: pain pathophysiology; pain prevention; predictive sensory testing; pre- and postoperative chronic pain; new biomarkers in pain; pain management and novel treatments; preemptive analgesia; inflammatory pain
(This special issue belongs to the Section Molecular and Translational Medicine)
Periodontal Inflammation, Periodontal Disease and Systemic Diseases
edited by Oelisoa Mireille Andriankaja
submission deadline 28 Feb 2025 | 3 articles | Viewed by 5480 | Submission Open
Keywords: periodontal disease; periodontitis; systemic diseases; biological mechanisms; correlation; inflammation; immune response; therapeutic targets
(This special issue belongs to the Section Immunology and Immunotherapy)
New Advances in Chronic Kidney Disease: Biology, Diagnosis and Therapy (2nd Edition) submission deadline 28 Feb 2025 | 5 articles | Viewed by 5094 | Submission Open
Keywords: inflammation; kidney biomarkers; kidney injury; chronic kidney disease; dialysis; cardiorenal syndrome risk; CKD anemia; kidney physiopathology; CKD treatment
(This special issue belongs to the Section Cell Biology and Pathology)
Soft Electronics Enabled Tissue Engineering and Characterization
edited by Muyang Lin
submission deadline 28 Feb 2025 | 2 articles | Viewed by 4900 | Submission Open
Keywords: soft electronics; tissue engineering; drug delivery; tissue repair; tissue characterization; healthcare
(This special issue belongs to the Section Biomedical Engineering and Materials)
Targeted Therapies for Cancers
edited by
submission deadline 28 Feb 2025 | 2 articles | Viewed by 4820 | Submission Open
Keywords: targeted therapy; precision medicine; combination therapy; recurrence mechanisms; immune modulation; cancer stem cell targeting; rna-based therapy; epigenetic therapy; cancer cell metabolism
(This special issue belongs to the Section Cancer Biology and Oncology)
Diagnosis, Pathogenesis, Treatment and Prognosis of Glioblastoma
edited by
submission deadline 28 Feb 2025 | 3 articles | Viewed by 4143 | Submission Open
Keywords: glioblastoma; immunotherapy; molecular subtype; radiotherapy; molecular therapy; emerging treatment; drug resistance; MRI; immune surveillance
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advancements in Artificial Intelligence (AI) for Cancer Genomics and Genetics submission deadline 28 Feb 2025 | 3 articles | Viewed by 4043 | Submission Open
Keywords: artificial intelligence; cancer; genetics; epigenetics; genomics; epigenomics; gene-environment interaction; cancer diagnosis and prognosis; personalized medicine; drug discovery
(This special issue belongs to the Section Cancer Biology and Oncology)
Molecular Characteristics of Cerebral Ischemia and Their Therapeutic Applications
edited by E-Jian Lee and Shengyang Huang
submission deadline 28 Feb 2025 | 3 articles | Viewed by 4019 | Submission Open
Keywords: cerebral ischemia; molecular mechanisms; pathophysiology; biomarkers; therapeutic strategies; neuroprotection; ischemic stroke; neuro-inflammation; translational research; neuroplasticity; neurophysiology; neuroscience; neuroelectrophysiology
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Biomedical and Biochemical Basis of Neurodegenerative Diseases
edited by
submission deadline 28 Feb 2025 | 3 articles | Viewed by 3842 | Submission Open
Keywords: neurodegeneration; personalized medicine; biomarkers; diagnosis; treatment
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Molecular Mechanisms and Treatment of Rheumatic Diseases
edited by Ruxandra Ionescu and
submission deadline 28 Feb 2025 | 2 articles | Viewed by 3650 | Submission Open
Keywords: rheumatology; immune-mediated rheumatic diseases; biologics; DMARDs; arthritis; lupus; vasculitis; spondyloarthritis; targets
(This special issue belongs to the Section Molecular and Translational Medicine)
Oral Cancer: From Pathophysiology to Novel Therapeutic Approaches Volume II submission deadline 28 Feb 2025 | 2 articles | Viewed by 3350 | Submission Open
Keywords: oral carcinogenesis; oral tumorigenesis; oral cancer; OSCC; ICI; mutation; biomarkers; chemoradiation; targeted therapies; cisplatin; preclinical models
(This special issue belongs to the Section Molecular and Translational Medicine)
Acute Pancreatitis: Biology, Diagnosis and Therapy
edited by Rajarshi Mukherjee
submission deadline 28 Feb 2025 | 2 articles | Viewed by 3118 | Submission Open
Keywords: pancreatitis; pathophysiology; inflammation; diagnostics; biomarkers; drug discovery
(This special issue belongs to the Section Molecular and Translational Medicine)
Recent Advances in Drug Synthesis and Drug Discovery
edited by Ramesh Prasad
submission deadline 28 Feb 2025 | 2 articles | Viewed by 2946 | Submission Open
Keywords: molecular docking; high-throughput virtual screening; computer-aided small molecular drug discovery; machine learning for advancing computational chemistry; molecular dynamics simulation
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Bioactive Peptides and Derivatives as Therapeutic Agents: Potential Applications in Disease Treatment
edited by
submission deadline 28 Feb 2025 | 1 articles | Viewed by 2912 | Submission Open
Keywords: bioactive peptide; peptide modification; application; cardiovascular disease; inflammatory disease; digestive disease; neurological disease; drug development
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Fatty Liver Disease: From Mechanisms to Therapeutic Approaches
edited by Mirela Baus Lončar
submission deadline 28 Feb 2025 | 2 articles | Viewed by 2783 | Submission Open
Keywords: fatty liver; metabolism; animal models of disease; gut– liver– brain axis; therapy
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Mechanisms and Pharmacological Targets for Pain
edited by Renan F. do Espírito-Santo
submission deadline 28 Feb 2025 | 1 articles | Viewed by 2695 | Submission Open
Keywords: drug discovery; chronic pain; inflammatory pain; mechanisms of action; pain pharmacology; immunomodulation; neuropathic pain
(This special issue belongs to the Section Molecular and Translational Medicine)
Emerging Issues in Retinal Degeneration submission deadline 28 Feb 2025 | 3 articles | Viewed by 2615 | Submission Open
Keywords: retinal degeneration; age-related macular degeneration (AMD); retinitis pigmentosa (RP); diabetic retinopathy; gene therapy; stem cell therapy; retinal implants; pharmacological treatments; diagnostic methods; molecular mechanisms; predictive biomarkers; imaging technologies; signaling pathways; oxidative stress; neuroprotection
(This special issue belongs to the Section Cell Biology and Pathology)
Inflammation and Peripheral Nervous System
edited by Nikolett Bódi
submission deadline 28 Feb 2025 | 2 articles | Viewed by 2566 | Submission Open
Keywords: pro- and anti-inflammatory molecules; peripheral nervous system; peripheral neuropathy; neuroinflammation; neuronal environment; neuro-immune interactions; anti-inflammatory therapies
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advanced Research in Pulmonary Pathophysiology
edited by Ourania S. Kotsiou and Erasmia Rouka
submission deadline 28 Feb 2025 | 1 articles | Viewed by 2342 | Submission Open
Keywords: pathophysiology; aging; disease; injury; microbiome; small airways; pleura; lung cancer; infections; critical care
(This special issue belongs to the Section Cell Biology and Pathology)
Neuroendocrine Neoplasia and Endocrine Tumors: Pathogenic Features, Prognostic Markers and New Therapeutic Approaches
edited by
submission deadline 28 Feb 2025 | 2 articles | Viewed by 2293 | Submission Open
Keywords: neuroendocrine tumors; endocrine tumors; somatostatin analogues; carcinoid syndrome; PRRT; mTOR inhibitor; lymph node; neuroendocrine marker; hormone; ki67
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Pharmaceutical Treatments for Typical CKD Comorbidities submission deadline 28 Feb 2025 | 1 articles | Viewed by 2122 | Submission Open
Keywords: natural bioactive compounds; adjuvant treatment; protein energy wasting; mineral bone disorders; metabolic acidosis; hyperhomocysteinemia; uremic sarcopenia; PLADO diet; anemia in CKD
(This special issue belongs to the Section Molecular and Translational Medicine)
Pollutants and Human Health: Focus on Molecular-Level Research submission deadline 28 Feb 2025 | 1 articles | Viewed by 2104 | Submission Open
Keywords: environmental exposure; emerging pollutants; human and ecosystem health; environmental risk assessment; adverse outcome pathways; human risk assessment; endocrine-disrupting chemicals; cardiovascular endocrinology; neurovascular endocrinology; reproductive toxicology
(This special issue belongs to the Section Molecular and Translational Medicine)
Retinal Vascular Disorders: New Insights into Pathogenesis, Diagnosis and Treatment
edited by Irini P. Chatziralli
submission deadline 28 Feb 2025 | 2 articles | Viewed by 2022 | Submission Open
Keywords: diabetic retinopathy; retinal vein occlusion; retinal artery occlusion; sickle-cell retinopathy; optical coherence tomography; widefield imaging; OCT angiography
(This special issue belongs to the Section Molecular and Translational Medicine)
Epigenetics and Metabolic Disorders
edited by Patrik Krumpolec
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1995 | Submission Open
Keywords: metabolic diseases; epigenetics; DNA methylation; histone modification; non-coding RNA (ncRNA)-mediated gene regulation; heredity; environmental factors
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Immunometabolic Determinants of Gut–Liver Axis Health submission deadline 28 Feb 2025 | 1 articles | Viewed by 1962 | Submission Open
Keywords: gut microbiota; 'entero-hepatic' axis; gut– liver axis; immunometabolism
(This special issue belongs to the Section Immunology and Immunotherapy)
Advances in Fetal Medicine and Neonatology submission deadline 28 Feb 2025 | 2 articles | Viewed by 1908 | Submission Open
Keywords: fetal medicine; neonatology; research innovations; perinatal care; clinical practices
(This special issue belongs to the Section Molecular and Translational Medicine)
Feature Reviews in Cell Death
edited by and Madalina Nistor
submission deadline 28 Feb 2025 | 2 articles | Viewed by 1906 | Submission Open
Keywords: cell death pathways; apoptosis; necrosis; biomarkers; therapies
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Advancements in Induced Pluripotent Stem Cells
edited by
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1672 | Submission Open
Keywords: induced pluripotent stem cells; organoids; tissue engineering; biomaterials; reprogramming; iPSC-based cell modelling; cell therapy; microfluidics; drug discovery
(This special issue belongs to the Section Gene and Cell Therapy)
Advancements in Lung Cancer Precision Oncology Research and Treatments
edited by , and Francesca Colonese
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1578 | Submission Open
Keywords: lung; cancer; NSCLC; targeted therapies; immunotherapy; precision oncology; EGFR; KRAS; ALK; ROS1
(This special issue belongs to the Section Cancer Biology and Oncology)
Innovative Approaches in In Vitro Skin Models: From Design to Application
edited by
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1574 | Submission Open
Keywords: in vitro skin models; tissue engineering; dermatological research; 3D skin bioprinting; skin disease modeling
(This special issue belongs to the Section Biomedical Engineering and Materials)
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