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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Women’s Special Issue Series: Biomedicines (2nd Edition)

edited by

Letizia Polito

Federica Falà

and

Riuko Ohashi

submission deadline 30 Apr 2026 | 8 articles | Viewed by 31386 | Submission Open

Keywords: antibody; biomedicines; biopharmaceutical products; cancer therapy; drug delivery; immunoconjugates; immunotoxins; immunotherapy; immunotargeting; nanodelivery; toxins

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Fetal Medicine and Neonatology

edited by

Robert Brawura-Biskupski-Samaha

submission deadline 30 Apr 2026 | 10 articles | Viewed by 25133 | Submission Open

Keywords: fetal medicine; neonatology; research innovations; perinatal care; clinical practices

(This special issue belongs to the Section Molecular and Translational Medicine)

Head and Neck Tumors, 4th Edition

edited by

Silvia Di Agostino

and

Jan B. Vermorken

submission deadline 30 Apr 2026 | 7 articles | Viewed by 20598 | Submission Open

Keywords: head and neck tumors; predictive markers; liquid biopsy; therapy; precision medicine; biomaterials

(This special issue belongs to the Section Cancer Biology and Oncology)

Neurodevelopmental Disorders: From Pathophysiology to Novel Therapeutic Approaches—2nd Edition

edited by Nader Perroud and Markus Mathaus Kosel

submission deadline 30 Apr 2026 | 5 articles | Viewed by 16670 | Submission Open

Keywords: intellectual disability; autism spectrum disorder; attention-deficit/hyperactivity disorder; drug treatment; neuroimaging

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Thyroid Disorders: Current Status and Future Prospects

edited by Anna Małgorzata Kucharska

submission deadline 30 Apr 2026 | 3 articles | Viewed by 11560 | Submission Open

Keywords: thyroid diseases; autoimmune thyroid diseases; hypothyroidism; hyperthyroidism; treatment; children; adults

(This special issue belongs to the Section Molecular and Translational Medicine)

Biomedicine in Dental and Oral Rehabilitation

edited by

Sanda Mihaela Popescu

and

Mihaela Ionescu

submission deadline 30 Apr 2026 | 6 articles | Viewed by 8829 | Submission Open

Keywords: diagnosis; treatment; oral rehabilitation; dental and oral disease; biomedicine; biomaterial; regeneration; functional; esthetics

(This special issue belongs to the Section Biomedical Engineering and Materials)

Gastrointestinal Diseases: From Pathophysiology to Innovative Therapeutic Approaches

edited by

Francisco Tustumi

submission deadline 30 Apr 2026 | 7 articles | Viewed by 6915 | Submission Open

Keywords: gastrointestinal diseases; pathophysiology; microbiome; inflammation; gastrointestinal cancer; translational medicine; therapeutic innovation; personalized treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Role of Endothelial Cells in Cardiovascular Disease—2nd Edition

edited by

Lorenzo Falsetti

and

Vincenzo Zaccone

submission deadline 30 Apr 2026 | 2 articles | Viewed by 5947 | Submission Open

Keywords: endothelial cells; endothelial dysfunction; cardiovascular disease; endothelial progenitor cells; atherosclerosis; thrombosis; vessel inflammation; regenerative medicine

(This special issue belongs to the Section Cell Biology and Pathology)

Advanced Research in Metabolic Syndrome (2nd Edition)

edited by

Balazs Varga

submission deadline 30 Apr 2026 | 3 articles | Viewed by 5313 | Submission Open

Keywords: obesity; diabetes; dyslipidemia; hypertension; microcirculatory damage; ischemia– reperfusion; necro-apopto-autophagy; laboratory animals; bioactive agents

(This special issue belongs to the Section Cell Biology and Pathology)

Advances in Stroke Neuroprotection and Repair

edited by

Konstantinos Tsamakis

submission deadline 30 Apr 2026 | 3 articles | Viewed by 4646 | Submission Open

Keywords: stroke; cerebral infarction; neuronal damage; neural regeneration; neuroprotection

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Unraveling New Horizon in Vascular Diseases: From Pathophysiology to Novel Therapeutic

edited by Miguel A. Ortega and

Raul Diaz-Pedrero

submission deadline 30 Apr 2026 | 2 articles | Viewed by 3970 | Submission Open

Keywords: vascular diseases; artery; venous disease; venous hypertension; heart; lymph; diabetes; surgery; immune system; translational medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Biomaterials for Bone Regeneration: 2nd Edition

edited by

Kyeong-Hyeon Park

submission deadline 30 Apr 2026 | 3 articles | Viewed by 3813 | Submission Open

Keywords: bone regeneration; bone defect; induced membrane technique; bone transport; biomaterials

(This special issue belongs to the Section Biomedical Engineering and Materials)

Advances in Periodontal Disease and Systemic Disease

edited by

Hye-Sun Shin

submission deadline 30 Apr 2026 | 3 articles | Viewed by 3142 | Submission Open

Keywords: periodontal disease; systemic health; inflammation; oral microbiome; cardiovascular disease; diabetes; cancer; oral– gut– brain axis; precision medicine; biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

New Perspectives in the Treatment of Head and Neck Vascular Malformations

edited by Paolo Gennaro

submission deadline 30 Apr 2026 | 1 articles | Viewed by 2902 | Submission Open

Keywords: vascular anomalies; vascular malformations; AVMs; venous malformations; electrosclerotherapy

(This special issue belongs to the Section Molecular and Translational Medicine)

Integrative Roles of Natural Products in Cancer Treatment and Chronic Inflammatory Disease

edited by

Seungho Baek

submission deadline 30 Apr 2026 | 4 articles | Viewed by 2868 | Submission Open

Keywords: natural products; cancer; chronic inflammatory diseases; therapy; oxidative stress

(This special issue belongs to the Section Molecular and Translational Medicine)

Mechanisms and Novel Therapeutic Approaches for Gliomas: 2nd Edition

edited by Maria V. Chatziathanasiadou

submission deadline 30 Apr 2026 | 3 articles | Viewed by 2654 | Submission Open

Keywords: glioma; molecular mechanisms; tumour immunity; tumour metabolism; tumour microenvironment; metabolic therapies; immunotherapies; combination treatment

(This special issue belongs to the Section Cancer Biology and Oncology)

Modern Applications of Advanced Imaging to Neurological Disease

edited by Manisha Koneru and

Hamza Adel Salim

submission deadline 30 Apr 2026 | 3 articles | Viewed by 2648 | Submission Open

Keywords: neuroimaging; cerebrovascular disease; neuro-oncology; compted tomography; magnetic resonance imaging; patient outcomes; neurosciences; neuroradiology

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Mechanobiology and Extracellular Vesicle-Based Strategies for Osteochondral Regeneration

edited by Zhen Yang

submission deadline 30 Apr 2026 | 2 articles | Viewed by 2647 | Submission Open

Keywords: biomechanics; stem cells; osteoarthritis; tissue engineering; extracellular vesicles

(This special issue belongs to the Section Biomedical Engineering and Materials)

Epigenetic Regulation of Kidney Development

edited by Hongbing Liu

submission deadline 30 Apr 2026 | 1 articles | Viewed by 2485 | Submission Open

Keywords: epigenetic regulation; kidney development; gene expression patterns; targeted therapeutic strategies; epigenetic regulation of kidney development

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Pathogenesis, Diagnosis and Treatment of Melanoma

edited by Vijayasteltar B. Liju

submission deadline 30 Apr 2026 | 2 articles | Viewed by 2137 | Submission Open

Keywords: melanoma; metastasis; targeted therapies; immunotherapy; tumor microenvironment; combination therapies; molecular pathways

(This special issue belongs to the Section Molecular and Translational Medicine)

Heart Failure: New Diagnostic and Therapeutic Approaches, 2nd Edition

edited by

Anand Prakash Singh

submission deadline 30 Apr 2026 | 2 articles | Viewed by 2068 | Submission Open

Keywords: heart failure; clinical treatment; basic cardiac research; future perspective; heart failure therapy; cardiotoxicity

(This special issue belongs to the Section Molecular and Translational Medicine)

Emerging Trends in Kidney Disease (2nd Edition)

edited by Andrea Angioi

submission deadline 30 Apr 2026 | 2 articles | Viewed by 1836 | Submission Open

Keywords: kidney disease; glomerular diseases; vasculitis; dialysis; hypertension; pediatric nephrology; transplantation; precision medicine; therapeutic advancements

(This special issue belongs to the Section Molecular and Translational Medicine)

Decoding Colorectal Cancer: Innovations in Biomarkers, Microbiota, and Therapeutic Resistance

edited by

Yinghao Cao

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1815 | Submission Open

Keywords: colorectal cancer; tumor biomarkers; nanomaterials; drug delivery; microbiome– tumor interaction; therapeutic resistance; exosomes; tumor microenvironment; prognostic model; neoadjuvant therapy; conversion therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Selected Papers from the Tanawwo Workshop on Clinical Research in Precision Medicine, Rare Diseases, and Pharmacogenomics (Doha, Qatar, 2025)

edited by

Felipe Fregni

and Radja Messai Badji

submission deadline 30 Apr 2026 | 2 articles | Viewed by 1744 | Submission Open

Keywords: precision medicine; rare diseases; pharmacogenomics; adaptive and platform trials; multi-omics integration; artificial intelligence in clinical research; big data and digital health; translational medicine

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances in Skin Tumors: From Pathogenesis to Treatment Strategies

edited by Zhongxin Yu and Sepideh Nikki Asadbeigi

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1719 | Submission Open

Keywords: melanoma skin; tumor epigenetic alterations; genetic mutations; tumor microenvironment immunotherapy; targeted therapy; nanomedicine

(This special issue belongs to the Section Cancer Biology and Oncology)

Recent Advances in Hypertension, Hypercholesterolemia and Type 2 Diabetes—2nd Edition

edited by

Tomislav Bulum

submission deadline 30 Apr 2026 | 3 articles | Viewed by 1679 | Submission Open

Keywords: type 2 diabetes; hypertension; LDL-cholesterol; serum lipids; metabolic syndrome; cardiovascular disease; chronic complications; nephropathy

(This special issue belongs to the Section Endocrinology and Metabolism Research)

New Advances in Neuropharmacology

edited by

Yu-Cheng Ho

and

Ming Tatt Lee

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1620 | Submission Open

Keywords: behavioral neuropharmacology; molecular neuropharmacology; neuropharmacology; neurological disorders; neurodegenerative diseases

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

From Pathogenesis to Therapies: Innovations in Kidney Disease

edited by

Tao Qiu

Jiefu Zhu

and Chenglin Wu

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1446 | Submission Open

Keywords: renal ischemia-reperfusion injury; acute kidney injury; renal fibrosis; chronic kidney disease; ureteral obstructive nephropathy; kidney transplantation; macrophage-myofibroblast transition; inflammation; fibroblast activation; chronic allograft rejection; potential therapy

(This special issue belongs to the Section Molecular and Translational Medicine)

Gynecological Cancers: Progress and Challenges

edited by

Yi-Fen Chiang

submission deadline 30 Apr 2026 | 2 articles | Viewed by 1386 | Submission Open

Keywords: gynecological cancer; therapeutic targets; precision medicine; immunotherapy; drug resistance; biomarkers; molecular mechanisms; natural compound; translational research; adjuvant therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Isoflavones as Therapeutic Leads: From Natural Sources to Mechanisms and Translational

edited by

Bruno Kaufmann Robbs

and

Lucas Silva Abreu

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1162 | Submission Open

Keywords: isoflavones; phytoestrogens; natural bioactive compounds; mechanisms of action; translational medicine; therapeutic development; drug discovery

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

New Advances in Cardiovascular Drugs: In Memory of Professor Akira Endo (2nd Edition)

edited by

Alfredo Caturano

submission deadline 30 Apr 2026 | 2 articles | Viewed by 1003 | Submission Open

Keywords: cardiovascular drugs; statins; metformin; SGLT2i; laboratory; drug targets; translational research; targeted therapy

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Advances in Chronic Obstructive Pulmonary Disease (COPD)

edited by Fabio Manzo and

Pasquale Ambrosino

submission deadline 30 Apr 2026 | 1 articles | Viewed by 970 | Submission Open

Keywords: chronic obstructive pulmonary disease; COPD; emphysema; chronic bronchitis; chronic disease; disability; rehabilitation

(This special issue belongs to the Section Cell Biology and Pathology)

Innovative Approaches in Drug Discovery

edited by Jitendra Gour

submission deadline 30 Apr 2026 | Viewed by 956 | Submission Open

Keywords: PROTACs; molecular glue; personalized medicine; high-throughput screening (HTS); targeted therapy; drug repurposing; safety profiles

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Innovative Therapeutic Strategies and Molecular Mechanisms in Breast Cancer

edited by

Oana Gabriela Trifanescu

and

Laurentia Nicoleta Gales

submission deadline 30 Apr 2026 | 1 articles | Viewed by 948 | Submission Open

Keywords: breast cancer; immunotherapy; medical imaging; biomarkers; translational research

(This special issue belongs to the Section Cancer Biology and Oncology)

Oxidative Stress, Inflammation and Endothelial Dysfunction in COVID-19 Era and Long COVID-19 Complications

edited by

Ekaterina Georgieva

submission deadline 30 Apr 2026 | 1 articles | Viewed by 940 | Submission Open

Keywords: oxidative stress; redox-disbalance; COVID-19; post-COVID-19; cytokines; mitochondrial dysfunction; endothelial damages; ROS and RNS; thrombosis; antioxidant therapy; oxidative shock

(This special issue belongs to the Section Molecular and Translational Medicine)

Alzheimer's Disease: Pathogenesis, Diagnostics and Novel Treatment Options

edited by

Rui Zhong

and Ling Li

submission deadline 30 Apr 2026 | 1 articles | Viewed by 855 | Submission Open

Keywords: amyloid and tau pathology; neuroinflammation and oxidative stress; neuromodulation; fluid biomarkers; imaging and other diagnostic approaches; small-molecule therapeutics; novel therapeutics and emerging therapies; disease-modifying therapies; experimental and clinical pharmacology

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Targeted Biologic Therapies for Allergic Conditions: From Bench to Bedside

edited by

Antonio Francesco Maria Giuliano

and Maria Teresa Ventura

submission deadline 30 Apr 2026 | 1 articles | Viewed by 849 | Submission Open

Keywords: biologics; allergic disease; atopic dermatitis; allergic rhinitis; asthma; precision medicine; biomarkers; immunotherapy

(This special issue belongs to the Section Immunology and Immunotherapy)

Advancements in Understanding and Treating Oral Pathologies: From Dry Mouth to Oral Cancer—2nd Edition

edited by Eleni Georgakopoulou and George Laskaris

submission deadline 30 Apr 2026 | 1 articles | Viewed by 848 | Submission Open

Keywords: oral pathologies; oral diseases; pathogenesis; therapeutic interventions; interdisciplinary nature of oral healthcare; xerostomia; dysgeusia; oral cancer; precancerous lesions; oral inflammatory conditions

(This special issue belongs to the Section Cell Biology and Pathology)

Expanding Opioid Receptor Pharmacology: From Pain Control to Novel Therapeutic Applications in Neurobiology, Immunology, and Psychiatry

edited by

Luca Gentilucci

submission deadline 30 Apr 2026 | 1 articles | Viewed by 757 | Submission Open

Keywords: opioid; pain; mood; stress; addiction; neuropeptides

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Selective Glucocorticoid Receptor Agonists and Modulators (SEGRAMs)

edited by

Dimitra Mitsiou

submission deadline 30 Apr 2026 | Viewed by 651 | Submission Open

Keywords: glucocorticoid receptor; glucocorticoids; transactivation; transrepression; selective glucocorticoid receptor agonists; selective glucocorticoid receptor modulators; inflammation; anti-inflammatory action; side effects; therapeutic potential

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Diabetic Nephropathy and Diabetic Atherosclerosis (2nd Edition)

edited by

Satyesh K. Sinha

submission deadline 30 Apr 2026 | 1 articles | Viewed by 522 | Submission Open

Keywords: diabetic nephropathy; diabetic atherosclerosis; diabetes; inflammation; oxidative stress; renal and vascular cell dysfunction; basic science; clinical practice; patient outcomes

(This special issue belongs to the Section Molecular and Translational Medicine)

Post Tuberculosis Lung Disease from Lung Damage to the Loss of Lung Function

edited by

Oana Cristina Arghir

and Ariadna Petronela Fildan

submission deadline 30 Apr 2026 | Viewed by 509 | Submission Open

Keywords: post-tuberculosis lung disease (PTLD); post-TB conditions; TB sequelae; obstructive post-TB disease; post-TB syndromes

(This special issue belongs to the Section Molecular and Translational Medicine)

Aging and Decoding Aging

edited by Bingrui Li, Xuanye Cao and Wen Jiang

submission deadline 30 Apr 2026 | 1 articles | Viewed by 476 | Submission Open

Keywords: aging; computational modeling; AI; healthspan and lifespan prediction; systems biology

(This special issue belongs to the Section Cell Biology and Pathology)

Bone Diseases: Pathophysiology and Molecular Biology

edited by

Tommaso Greco

Carlo Perisano

and Nicola De Gasperis

submission deadline 30 Apr 2026 | Viewed by 474 | Submission Open

Keywords: bone diseases; osteoporosis; osteoarthritis; Paget’ s disease; bone tumors

(This special issue belongs to the Section Molecular and Translational Medicine)

Bone Metabolism in Health and Disease

edited by

Kun Chen

submission deadline 30 Apr 2026 | Viewed by 437 | Submission Open

Keywords: bone remodeling; skeletal stem cells; osteocyte; osteoblasts; osteoclasts; osteoporosis; osteoarthritis; bone regeneration; bone aging; bone therapeutics

(This special issue belongs to the Section Molecular and Translational Medicine)

Targeting Mast Cells in Human Disease: Bridging Pathology and Therapy

edited by Marianna Criscuolo

submission deadline 30 Apr 2026 | Viewed by 374 | Submission Open

Keywords: mast cell; mast cell activation syndrome; anaphylaxis; mastocytosis; anti-mediator therapy

(This special issue belongs to the Section Immunology and Immunotherapy)

Nanoparticle-Labeled Exosomes as Theranostic Agents

edited by Karrer M. Alghazali

submission deadline 30 Apr 2026 | Viewed by 340 | Submission Open

Keywords: exosomes; nanotheranostic agent; nanoparticles; exosome labeling; photothermal therapy; drug delivery vehicle; imaging probe

(This special issue belongs to the Section Cell Biology and Pathology)

Advances in Ocular Surface Disease

edited by

Kofi Asiedu

submission deadline 30 Apr 2026 | Viewed by 325 | Submission Open

Keywords: dry eye disease; corneal neuroimmune interactions; meibomian gland dysfunction; microbial keratitis; ocular allergy; corneal degeneration

(This special issue belongs to the Section Molecular and Translational Medicine)

Correlative Light and Electron Microscopy (CLEM) in Biomedicine: Advances and Applications

edited by

Hideya Kawasaki

submission deadline 30 Apr 2026 | Viewed by 315 | Submission Open

Keywords: CLEM; correlative microscopy; biomedicine; pathology; virology; oncology; immunolabeling; cryo-microscopy; ultrastructure; image analysis

(This special issue belongs to the Section Cell Biology and Pathology)

Animal Models in Pulmonary Research: Shaping the Future of Translational Respiratory Medicine

edited by

Badrul Hisham Yahaya

submission deadline 30 Apr 2026 | Viewed by 302 | Submission Open

Keywords: pulmonary disease; lung regeneration and repair; animal models; genetically modified models; lung injury induction; translational research

(This special issue belongs to the Section Molecular and Translational Medicine)

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