Processes, Volume 10, Issue 11
November 2022 - 310 articles
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Cover Story: Ceftobiprole is a broad-spectrum fifth-generation cephalosporin with activity against Gram-positives such as methicillin-resistant Staphylococcus aureus and penicillin-resistant Streptococcus pneumoniae, and against Gram-negatives such as Pseudomonas aeruginosa. Today, searching for new antibiotics is particularly important, especially due to the problem of increasing bacterial resistance. Similar, carrying out tests allows us to develop procedures enabling the determination of active substances both in pure form and a complex matrix, allowing quick and continuous monitoring of drug concentrations during therapy. The developed procedure for the determination of ceftobiprole in biological material using TLC chromatography with densitometric detection can be successfully used for laboratory practice. View this paper