Special Issue "Applications of Chromatographic Separation Techniques in Food and Chemistry"

A special issue of Processes (ISSN 2227-9717). This special issue belongs to the section "Green Processes".

Deadline for manuscript submissions: 30 June 2020.

Special Issue Editors

Prof. Dr. Alina Pyka-Pająk
Website
Guest Editor
Department of Analytical Chemistry, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Jagiellońska 4, 41-200 Sosnowiec, Poland
Interests: liquid chromatography; spectrophotometry; densitometry; organic compounds analysis; QSAR; QSRR; QSPR; pharmaceutical analysis; purity of pharmaceutical preparations
Dr. Małgorzata Dołowy
Website
Co-Guest Editor
Department of Analytical Chemistry, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Jagiellońska 4, 41-200 Sosnowiec, Poland
Interests: application of different analytical methods, including liquid chromatography, in pharmaceutical and biomedical analysis

Special Issue Information

Dear Colleagues,

Chromatographic techniques are by far the most powerful and versatile methods available to the modern analyst. Because of their good separation capacity, various chromatographic methods combined with modern detection systems are able to quickly separate very complicated mixtures into their individual components in a single-step process and are also capable of simultaneous quantitative determination of each constituent.

Currently, chromatography is an extremely versatile technique allowing to rapidly separate gases and volatile substances by gas chromatography, involatile chemicals and materials of extremely high molecular weight by liquid chromatography, and if necessary, very inexpensively by thin-layer chromatography coupled to densitometry. Therefore, chromatographic analyses are a widespread research method used in virtually all industries, involving also food processing as well as chemical synthesis. They allow the detection of even trace amounts of substances in the finished product, which in turn gives the possibility of meticulous quality control of food products or purity of newly synthesized bioactive molecules as potential new drug candidates and others.

This Special Issue on “Applications of Chromatographic Separation Techniques in Food and Chemistry” aims to curate novel advances in the development and application of chromatographic separation techniques in food and chemical analyses. Topics include but are not limited to:

  • Chromatographic techniques used in ascertaining food quality and authenticity;
  • Chromatographic analysis of food additives including food preservatives, antioxidants, sweeteners, colors, etc.;
  • Basic research and applications of chromatographic techniques in chemistry;
  • The development of new chromatographic methods in the analysis of food and chemical compounds, including bioactive molecules;
  • Chromatography as separation technique useful in the chemical process industry; for analysis, isolation, and purification of various chemical compounds as the components of small- and large-scale production.

Original research papers as well as reviews related to the areas mentioned above are most welcome.

Prof. Dr. Alina Pyka-Pająk
Dr. Małgorzata Dołowy
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Please note that for papers submitted after 30 June 2020 an APC of 1500 CHF applies. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chromatographic techniques (GC, HPLC, TLC, TLC-densitometry)
  • food components
  • food quality
  • chemical analysis
  • analysis of bioactive compounds
  • separation techniques

Published Papers (2 papers)

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Research

Open AccessFeature PaperArticle
TLC-Densitometric Determination of Five Coxibs in Pharmaceutical Preparations
Processes 2020, 8(5), 620; https://doi.org/10.3390/pr8050620 - 22 May 2020
Abstract
A class of drugs called coxibs (COX-2 inhibitors) were created to help relieve pain and inflammation of osteoarthritis and rheumatoid arthritis with the lowest amount of side effects possible. The presented paper describes a new developed, optimized and validated thin layer chromatographic (TLC)-densitometric [...] Read more.
A class of drugs called coxibs (COX-2 inhibitors) were created to help relieve pain and inflammation of osteoarthritis and rheumatoid arthritis with the lowest amount of side effects possible. The presented paper describes a new developed, optimized and validated thin layer chromatographic (TLC)-densitometric procedure for the simultaneous assay of five coxibs: celecoxib, etoricoxib, firecoxib, rofecoxib and cimicoxib. Chromatographic separation was conducted on HPTLC F254 silica gel chromatographic plates as a stationary phase using chloroform–acetone–toluene (12:5:2, v/v/v) as a mobile phase. Densitometric detection was carried out at two wavelengths of 254 and 290 nm. The method was tested according to ICH guidelines for linearity, recovery and specificity. The presented method was linear in a wide range of concentrations for all analyzed compounds, with correlation coefficients greater than 0.99. The method is specific, precise (%RSD < 1) and accurate (more than 95%, %RSD < 2). Low-cost, simple and rapid, it can be used in laboratories for drug monitoring and quality control. Full article
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Open AccessFeature PaperArticle
Response Surface Methodology as a Useful Tool for Evaluation of the Recovery of the Fluoroquinolones from Plasma—The Study on Applicability of Box-Behnken Design, Central Composite Design and Doehlert Design
Processes 2020, 8(4), 473; https://doi.org/10.3390/pr8040473 - 17 Apr 2020
Abstract
The aim of this study was to find the best design that is suitable for optimizing the recovery of the representatives of the 2nd, 3rd and 4th generation of fluoroquinolones. The following designs were applied: Central Composite Design, Box–Behnken Design and Doehlert Design. [...] Read more.
The aim of this study was to find the best design that is suitable for optimizing the recovery of the representatives of the 2nd, 3rd and 4th generation of fluoroquinolones. The following designs were applied: Central Composite Design, Box–Behnken Design and Doehlert Design. The recovery, which was a dependent variable, was estimated for liquid–liquid extraction. The time of shaking, pH, and the volume of the extracting agent (dichloromethane) were the independent variables. All results underwent the statistical analysis (ANOVA), which indicated Central Composite Design as the best model for evaluation of the recovery. For each analyte, an equation was generated that enabled to estimate the theoretical value for the applied conditions. The graphs for these equations were provided by the Response Surface Methodology. The statistical analysis also estimated the most significant factors that have an impact on the liquid–liquid extraction, which occurred to be pH for ciprofloxacin and moxifloxacin and the volume of an extracting solvent for levofloxacin. Full article
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