Applied Sciences, Volume 12, Issue 19
2022 October-1 - 792 articles
Cover Story: We present a novel, noninvasive, super-continuum infrared spectroscopy of a cytochrome-c-oxidase (SCISCCO) system for simultaneously measuring hemodynamic and metabolic parameters, and we demonstrate its utility by applying it to human and swine animal studies. The system optically assays the redox state of cytochrome c oxidase, as well as traditional markers, including oxygenated and deoxygenated hemoglobin. To enable use of the SCISCCO system in laboratory and hospital settings, a cart-based SCISCCO prototype system has also been developed. First, the SCISCCO system is applied in human studies to measure cerebral oxygenation and the redox state of CCO in participants during an attention test protocol. Second, the SCISCCO system is applied to swine animal models undergoing induction of hemorrhagic shock followed by partial resuscitative endovascular balloon occlusion of the aorta. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
- You may sign up for email alerts to receive table of contents of newly released issues.
- PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.