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Nutrients, Volume 6, Issue 12

2014 December - 44 articles

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Articles (44)

  • Review
  • Open Access
146 Citations
14,607 Views
18 Pages

The Impact of Anemia on Child Mortality: An Updated Review

  • Samuel P. Scott,
  • Lenis P. Chen-Edinboro,
  • Laura E. Caulfield and
  • Laura E. Murray-Kolb

22 December 2014

Iron deficiency anemia and child mortality are public health problems requiring urgent attention. However, the degree to which iron deficiency anemia contributes to child mortality is unknown. Here, we utilized an exhaustive article search and screen...

  • Review
  • Open Access
33 Citations
10,531 Views
22 Pages

22 December 2014

Sugar intake has dramatically increased during the last few decades. Specifically, there has been a clear trend towards higher consumption of fructose and high fructose corn syrup, which are the most common added sugars in processed food, soft drinks...

  • Review
  • Open Access
122 Citations
28,477 Views
20 Pages

22 December 2014

Sugar and sweet consumption have been popular and intrinsic to Indian culture, traditions, and religion from ancient times. In this article, we review the data showing increasing sugar consumption in India, including traditional sources (jaggery and...

  • Article
  • Open Access
47 Citations
10,332 Views
17 Pages

Anemia and Feeding Practices among Infants in Rural Shaanxi Province in China

  • Renfu Luo,
  • Yaojiang Shi,
  • Huan Zhou,
  • Ai Yue,
  • Linxiu Zhang,
  • Sean Sylvia,
  • Alexis Medina and
  • Scott Rozelle

22 December 2014

Anemia is one of the most prevalent public health problems among infants and iron deficiency anemia has been related to many adverse consequences. The overall goal of this study is to examine the prevalence of anemia among infants in poor rural Chin...

  • Article
  • Open Access
31 Citations
7,350 Views
13 Pages

Effects of Levocarnitine on Brachial-Ankle Pulse Wave Velocity in Hemodialysis Patients: A Randomized Controlled Trial

  • Terumi Higuchi,
  • Masanori Abe,
  • Toshio Yamazaki,
  • Mari Mizuno,
  • Erina Okawa,
  • Hideyuki Ando,
  • Osamu Oikawa,
  • Kazuyoshi Okada,
  • Fumito Kikuchi and
  • Masayoshi Soma

22 December 2014

Background and Aims: Atherosclerotic cardiovascular disease is the most common cause of mortality in patients with end-stage kidney disease. Chronic kidney disease patients often exhibit a deficiency in l-carnitine due to loss during hemodialysis (HD...

  • Article
  • Open Access
55 Citations
13,779 Views
15 Pages

22 December 2014

ncreasing evidence has suggested an association between dietary magnesium intake and metabolic syndrome. However, previous research examining dietary magnesium intake and metabolic syndrome has produced mixed results. Our objective was to determine t...

  • Review
  • Open Access
800 Citations
28,249 Views
28 Pages

Resources and Biological Activities of Natural Polyphenols

  • An-Na Li,
  • Sha Li,
  • Yu-Jie Zhang,
  • Xiang-Rong Xu,
  • Yu-Ming Chen and
  • Hua-Bin Li

22 December 2014

The oxidative stress imposed by reactive oxygen species (ROS) plays an important role in many chronic and degenerative diseases. As an important category of phytochemicals, phenolic compounds universally exist in plants, and have been considered to h...

  • Article
  • Open Access
90 Citations
9,795 Views
12 Pages

Neurochemical Effects of Chronic Administration of Calcitriol in Rats

  • Pei Jiang,
  • Li-Hong Zhang,
  • Hua-Lin Cai,
  • Huan-De Li,
  • Yi-Ping Liu,
  • Mi-Mi Tang,
  • Rui-Li Dang,
  • Wen-Ye Zhu,
  • Ying Xue and
  • Xin He

22 December 2014

Despite accumulating data showing the various neurological actions of vitamin D (VD), its effects on brain neurochemistry are still far from fully understood. To further investigate the neurochemical influence of VD, we assessed neurotransmitter syst...

  • Article
  • Open Access
97 Citations
10,841 Views
16 Pages

Intake of Seafood in the US Varies by Age, Income, and Education Level but Not by Race-Ethnicity

  • Lisa Jahns,
  • Susan K. Raatz,
  • LuAnn K. Johnson,
  • Sibylle Kranz,
  • Jeffrey T. Silverstein and
  • Matthew J. Picklo

22 December 2014

Current US federal dietary guidance recommends regular consumption of seafood (fish + shellfish) to promote health; however, little is known about how well Americans meet the guideline, particularly population subgroups that may be at risk for inadeq...

  • Conference Report
  • Open Access
27 Citations
15,383 Views
19 Pages

Selected Nutrients and Their Implications for Health and Disease across the Lifespan: A Roadmap

  • Szabolcs Péter,
  • Manfred Eggersdorfer,
  • Dieneke Van Asselt,
  • Erik Buskens,
  • Patrick Detzel,
  • Karen Freijer,
  • Berthold Koletzko,
  • Klaus Kraemer,
  • Folkert Kuipers and
  • Peter Weber
  • + 4 authors

22 December 2014

Worldwide approximately two billion people have a diet insufficient in micronutrients. Even in the developed world, an increasing number of people consume nutrient-poor food on a regular basis. Recent surveys in Western countries consistently indicat...

  • Review
  • Open Access
47 Citations
9,650 Views
15 Pages

The Role of Dietary Fat throughout the Prostate Cancer Trajectory

  • Katie M. Di Sebastiano and
  • Marina Mourtzakis

22 December 2014

Prostate cancer is the second most common cancer diagnosed world-wide; however, patients demonstrate exceptionally high survival rates. Many lifestyle factors, including obesity and diet, are considered risk factors for advanced prostate cancer. Diet...

  • Article
  • Open Access
5 Citations
7,978 Views
15 Pages

Distribution and Determinants of Plasma Homocysteine Levels in Rural Chinese Twins across the Lifespan

  • Yuelong Ji,
  • Xiangyi Kong,
  • Guoying Wang,
  • Xiumei Hong,
  • Xin Xu,
  • Zhu Chen,
  • Tami Bartell,
  • Xiping Xu,
  • Genfu Tang and
  • Binyan Wang
  • + 3 authors

18 December 2014

Plasma homocysteine (Hcy) is a modifiable, independent risk factor for cardiovascular disease (CVD) and is affected by both environmental and genetic factors. This study aimed to describe the gender- and age-specific distribution of Hcy concentration...

  • Article
  • Open Access
15 Citations
7,252 Views
12 Pages

17 December 2014

A possibility to assess body composition during pregnancy is often important. Estimating body density (DB) and use the two-component model (2CM) to calculate total body fat (TBF) represents an option. However, this approach has been insufficiently ev...

  • Article
  • Open Access
39 Citations
10,594 Views
17 Pages

Effects of Resveratrol Supplementation on Bone Growth in Young Rats and Microarchitecture and Remodeling in Ageing Rats

  • Alice M. C. Lee,
  • Tetyana Shandala,
  • Long Nguyen,
  • Beverly S. Muhlhausler,
  • Ke-Ming Chen,
  • Peter R. Howe and
  • Cory J. Xian

16 December 2014

Osteoporosis is a highly prevalent skeletal disorder in the elderly that causes serious bone fractures. Peak bone mass achieved at adolescence has been shown to predict bone mass and osteoporosis related risk fracture later in life. Resveratrol, a na...

  • Article
  • Open Access
47 Citations
16,968 Views
20 Pages

Astaxanthin Supplementation Delays Physical Exhaustion and Prevents Redox Imbalances in Plasma and Soleus Muscles of Wistar Rats

  • Tatiana G. Polotow,
  • Cristina V. Vardaris,
  • Andrea R. Mihaliuc,
  • Marina S. Gonçalves,
  • Benedito Pereira,
  • Douglas Ganini and
  • Marcelo P. Barros

12 December 2014

Astaxanthin (ASTA) is a pinkish-orange carotenoid commonly found in marine organisms, especially salmon. ASTA is a powerful antioxidant and suggested to provide benefits for human health, including the inhibition of LDL oxidation, UV-photoprotection,...

  • Article
  • Open Access
40 Citations
9,315 Views
14 Pages

A Novel Role of Eruca sativa Mill. (Rocket) Extract: Antiplatelet (NF-κB Inhibition) and Antithrombotic Activities

  • Eduardo Fuentes,
  • Marcelo Alarcón,
  • Manuel Fuentes,
  • Gilda Carrasco and
  • Iván Palomo

12 December 2014

Background: Epidemiological studies have shown the prevention of cardiovascular diseases through the regular consumption of vegetables. Eruca sativa Mill., commonly known as rocket, is a leafy vegetable that has anti-inflammatory activity. However, i...

  • Article
  • Open Access
9 Citations
7,926 Views
18 Pages

The Protective Effect of Rhizoma Dioscoreae Extract against Alveolar Bone Loss in Ovariectomized Rats via Regulating Wnt and p38 MAPK Signaling

  • Zhiguo Zhang,
  • Lihua Xiang,
  • Dong Bai,
  • Wenlai Wang,
  • Yan Li,
  • Jinghua Pan,
  • Hong Liu,
  • Shaojun Wang,
  • Gary Guishan Xiao and
  • Dahong Ju

12 December 2014

Aim: The aim of this study was to evaluate the osteoprotective effect of aqueous Rhizoma Dioscoreae extract (RDE) on the alveolar bone of rats with ovariectomy-induced bone loss. Methods: Female Wistar rats were subjected to either ovariectomy or a s...

  • Article
  • Open Access
23 Citations
12,320 Views
14 Pages

Effect of Tea Theaflavins and Catechins on Microvascular Function

  • Dagmar Fuchs,
  • Young De Graaf,
  • Roeland Van Kerckhoven and
  • Richard Draijer

11 December 2014

Beneficial effects of flavonoid-rich black and green tea on macrocirculation have been well established. Theaflavins are unique to black tea as they are formed from catechins during the enzymatic oxidation of tea leaves. The study was performed to ga...

  • Review
  • Open Access
209 Citations
20,678 Views
20 Pages

11 December 2014

The human body is colonized by a large number of microbes coexisting peacefully with their host. The most colonized site is the gastrointestinal tract (GIT). More than 70% of all the microbes in the human body are in the colon. The microorganism popu...

  • Article
  • Open Access
12 Citations
6,449 Views
13 Pages

Urban-Rural Differences Explain the Association between Serum 25-Hydroxyvitamin D Level and Insulin Resistance in Korea

  • Bo Mi Song,
  • Yumie Rhee,
  • Chang Oh Kim,
  • Yoosik Youm,
  • Kyoung Min Kim,
  • Eun Young Lee,
  • Ju-Mi Lee,
  • Young Mi Yoon and
  • Hyeon Chang Kim

11 December 2014

An increasing number of studies report associations between low serum 25-hydroxyvitamin D [25(OH)D] level and insulin resistance; however, whether low vitamin D levels directly contribute to increased insulin resistance is unclear. We investigated t...

  • Review
  • Open Access
118 Citations
17,974 Views
25 Pages

The Role of Dietary Sugars and De novo Lipogenesis in Non-Alcoholic Fatty Liver Disease

  • J. Bernadette Moore,
  • Pippa J. Gunn and
  • Barbara A. Fielding

10 December 2014

Dietary sugar consumption, in particular sugar-sweetened beverages and the monosaccharide fructose, has been linked to the incidence and severity of non-alcoholic fatty liver disease (NAFLD). Intervention studies in both animals and humans have shown...

  • Article
  • Open Access
12 Citations
8,604 Views
20 Pages

10 December 2014

A high cholesterol diet induces dyslipidemia. This study investigated whether isoflavone aglycones in lactic acid-fermented soy milk (LFS) improve lipid metabolism in rats fed a high cholesterol diet. Male Sprague-Dawley rats aged seven weeks were fe...

  • Review
  • Open Access
4 Citations
7,428 Views
16 Pages

Insights from Space: Potential Role of Diet in the Spatial Organization of Chromosomes

  • Justin M. O'Sullivan,
  • Malina D. Doynova,
  • Jisha Antony,
  • Florian Pichlmuller and
  • Julia A. Horsfield

10 December 2014

We can now sequence and identify genome wide epigenetic patterns and perform a variety of “genomic experiments” within relatively short periods of time—ranging from days to weeks. Yet, despite these technological advances, we have a poor understandin...

  • Article
  • Open Access
23 Citations
8,600 Views
16 Pages

10 December 2014

Dietary therapy is the mainstay of treatment for diabetes. This study examined the effect of a low glycemic index (GI) multi-nutrient supplement, consumed in place of breakfast, on glycemic control in patients with type 2 diabetes mellitus (T2DM). A...

  • Article
  • Open Access
33 Citations
9,341 Views
14 Pages

Application of Coenzyme Q10 for Accelerating Soft Tissue Wound Healing after Tooth Extraction in Rats

  • Toshiki Yoneda,
  • Takaaki Tomofuji,
  • Yuya Kawabata,
  • Daisuke Ekuni,
  • Tetsuji Azuma,
  • Kota Kataoka,
  • Muneyoshi Kunitomo and
  • Manabu Morita

10 December 2014

Accelerating wound healing after tooth extraction is beneficial in dental treatment. Application of antioxidants, such as reduced coenzyme Q10 (rCoQ10), may promote wound healing after tooth extraction. In this study, we examined the effects of topic...

  • Correction
  • Open Access
5,432 Views
2 Pages

10 December 2014

We have found an inadvertent error in our paper published in Nutrients [1]. One standard error was not converted into standard deviation and this affected the following effect sizes and intelligence quotient (IQ):[...]

  • Article
  • Open Access
30 Citations
11,089 Views
16 Pages

Zinc Absorption from Micronutrient Powder Is Low but Is not Affected by Iron in Kenyan Infants

  • Fabian Esamai,
  • Edward Liechty,
  • Justus Ikemeri,
  • Jamie Westcott,
  • Jennifer Kemp,
  • Diana Culbertson,
  • Leland V. Miller,
  • K. Michael Hambidge and
  • Nancy F. Krebs

8 December 2014

Interference with zinc absorption is a proposed explanation for adverse effects of supplemental iron in iron-replete children in malaria endemic settings. We examined the effects of iron in micronutrient powder (MNP) on zinc absorption after three mo...

  • Article
  • Open Access
94 Citations
11,553 Views
15 Pages

A Novel Hemp Seed Meal Protein Hydrolysate Reduces Oxidative Stress Factors in Spontaneously Hypertensive Rats

  • Abraham T. Girgih,
  • Adeola M. Alashi,
  • Rong He,
  • Sunday A. Malomo,
  • Pema Raj,
  • Thomas Netticadan and
  • Rotimi E. Aluko

8 December 2014

This report shows the antioxidant effects of a hemp seed meal protein hydrolysate (HMH) in spontaneously hypertensive rats (SHR). Defatted hemp seed meal was hydrolyzed consecutively with pepsin and pancreatin to yield HMH, which was incorporated int...

  • Article
  • Open Access
42 Citations
8,530 Views
12 Pages

Nrf2-Mediated HO-1 Induction Contributes to Antioxidant Capacity of a Schisandrae Fructus Ethanol Extract in C2C12 Myoblasts

  • Ji Sook Kang,
  • Min Ho Han,
  • Gi-Young Kim,
  • Cheol Min Kim,
  • Byung Woo Kim,
  • Hye Jin Hwang and
  • Yung Hyun Choi

8 December 2014

This study was designed to confirm the protective effect of Schisandrae Fructus, which are the dried fruits of Schisandra chinensis (Turcz.) Baill, against oxidative stress-induced cellular damage and to elucidate the underlying mechanisms in C2C12...

  • Article
  • Open Access
40 Citations
7,602 Views
11 Pages

Vitamin D Status and Related Factors in Newborns in Shanghai, China

  • Xiaodan Yu,
  • Weiye Wang,
  • Zhenzhen Wei,
  • Fengxiu Ouyang,
  • Lisu Huang,
  • Xia Wang,
  • Yanjun Zhao,
  • Huijuan Zhang and
  • Jun Zhang

4 December 2014

With the increasing recognition of the importance of the non-skeletal effects of vitamin D (VitD), more and more attention has been drawn to VitD status in early life. However, the VitD status of newborns and factors that influence VitD levels in Sha...

  • Communication
  • Open Access
41 Citations
8,779 Views
8 Pages

Vitamin B12 in Obese Adolescents with Clinical Features of Insulin Resistance

  • Mandy Ho,
  • Jocelyn H. Halim,
  • Megan L. Gow,
  • Nouhad El-Haddad,
  • Teresa Marzulli,
  • Louise A. Baur,
  • Chris T. Cowell and
  • Sarah P. Garnett

4 December 2014

Emerging evidence indicates an association between obesity, metformin use and reduced vitamin B12 status, which can have serious hematologic, neurologic and psychiatric consequences. This study aimed to examine B12 status in obese adolescents with p...

  • Article
  • Open Access
97 Citations
12,686 Views
17 Pages

Psychometric Properties of Spanish Version of the Three-Factor Eating Questionnaire-R18 (Tfeq-Sp) and Its Relationship with Some Eating- and Body Image-Related Variables

  • Ignacio Jáuregui-Lobera,
  • Patricia García-Cruz,
  • Rocío Carbonero-Carreño,
  • Alejandro Magallares and
  • Inmaculada Ruiz-Prieto

4 December 2014

The aims of this study were to analyze the psychometric properties of the Spanish version of the Three-Factor Eating Questionnaire-R18 (TFEQ-SP), as well as determine its validity by evaluating the relationship of the TFEQ-SP with different parameter...

  • Review
  • Open Access
95 Citations
14,455 Views
17 Pages

The Role of Intestinal Bacteria Overgrowth in Obesity-Related Nonalcoholic Fatty Liver Disease

  • Silvia M. Ferolla,
  • Geyza N. A. Armiliato,
  • Cláudia A. Couto and
  • Teresa C. A. Ferrari

3 December 2014

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide. It is a progressive disorder involving a spectrum of conditions that include pure steatosis without inflammation, nonalcoholic steatohepatitis (NASH), fibros...

  • Review
  • Open Access
65 Citations
18,417 Views
27 Pages

Does Vitamin C Deficiency Promote Fatty Liver Disease Development?

  • David Højland Ipsen,
  • Pernille Tveden-Nyborg and
  • Jens Lykkesfeldt

1 December 2014

Obesity and the subsequent reprogramming of the white adipose tissue are linked to human disease-complexes including metabolic syndrome and concurrent non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). The dietary imp...

  • Article
  • Open Access
26 Citations
11,070 Views
17 Pages

Bee Pollen Improves Muscle Protein and Energy Metabolism in Malnourished Old Rats through Interfering with the Mtor Signaling Pathway and Mitochondrial Activity

  • Jérôme Salles,
  • Nicolas Cardinault,
  • Véronique Patrac,
  • Alexandre Berry,
  • Christophe Giraudet,
  • Marie-Laure Collin,
  • Audrey Chanet,
  • Camille Tagliaferri,
  • Philippe Denis and
  • Stéphane Walrand
  • + 2 authors

1 December 2014

Although the management of malnutrition is a priority in older people, this population shows a resistance to refeeding. Fresh bee pollen contains nutritional substances of interest for malnourished people. The aim was to evaluate the effect of fresh...

  • Review
  • Open Access
27 Citations
8,142 Views
17 Pages

PCSK9 Antibodies for the Treatment of Hypercholesterolemia

  • Ioanna Gouni-Berthold and
  • Heiner K. Berthold

1 December 2014

The serine protease proprotein convertase subtilisin/kexin type 9 (PCSK9) binds to the low-density lipoprotein (LDL) receptor (LDLR) and directs it to lysosomes for intracellular degradation. This results in decreased numbers of LDLR available on the...

  • Review
  • Open Access
62 Citations
10,092 Views
26 Pages

1 December 2014

High salt intake increases the risk of hypertension and cardiovascular diseases. Given the role of knowledge as a determinant of food intake, this paper aims to review the current levels of salt knowledge and the association between salt knowledge an...

  • Article
  • Open Access
7 Citations
5,638 Views
12 Pages

Subclinical Cardiovascular Damage and Fat Utilization in Overweight/Obese Individuals Receiving the Same Dietary and Pharmacological Interventions

  • Tiziana Montalcini,
  • Theodora Lamprinoudi,
  • Gaetano Gorgone,
  • Yvelise Ferro,
  • Stefano Romeo and
  • Arturo Pujia

1 December 2014

Subclinical organ damage precedes the occurrence of cardiovascular events in individuals with obesity and hypertension. The aim of this study was to assess the relationship between fuel utilization and subclinical cardiovascular damage in overweight/...

  • Communication
  • Open Access
15 Citations
5,801 Views
11 Pages

Supplementation of Adult Rats with Moderate Amounts of β-Carotene Modulates the Redox Status in Plasma without Exerting Pro-Oxidant Effects in the Brain: A Safer Alternative to Food Fortification with Vitamin A?

  • Carlos Eduardo Schnorr,
  • Maurilio Da Silva Morrone,
  • André Simões-Pires,
  • Leonardo Da Silva Bittencourt,
  • Fares Zeidán-Chuliá and
  • José Cláudio Fonseca Moreira

1 December 2014

Despite the antioxidant potential of vitamin A, recent studies reported that chronic retinol ester supplementation can also exert pro-oxidant effects and neurotoxicity in vivo and raises the mortality rates among healthy subjects. Our aim was to find...

  • Review
  • Open Access
144 Citations
29,405 Views
20 Pages

28 November 2014

Vitamin E is an important antioxidant that primarily protects cells from damage associated with oxidative stress caused by free radicals. The brain is highly susceptible to oxidative stress, which increases during ageing and is considered a major con...

  • Article
  • Open Access
34 Citations
9,982 Views
19 Pages

The Omega-3 Fatty Acid Docosahexaenoic Acid Attenuates Organic Dust-Induced Airway Inflammation

  • Tara M. Nordgren,
  • Taylor D. Friemel,
  • Art J. Heires,
  • Jill A. Poole,
  • Todd A. Wyatt and
  • Debra J. Romberger

27 November 2014

Workers exposed to organic dusts from concentrated animal feeding operations (CAFOs) are at risk for developing airway inflammatory diseases. Available preventative and therapeutic measures for alleviating dust-induced lung disease are inadequate. Be...

  • Article
  • Open Access
58 Citations
9,441 Views
13 Pages

Inappropriate Usage of Dietary Supplements in Patients by Miscommunication with Physicians in Japan

  • Tsuyoshi Chiba,
  • Yoko Sato,
  • Tomoko Nakanishi,
  • Kaori Yokotani,
  • Sachina Suzuki and
  • Keizo Umegaki

26 November 2014

Recently, people have used dietary supplements not only for nutritional supplementation, but also for treatment of their diseases. However, use of dietary supplements to treat diseases, especially with medications, may cause health problems in patien...

  • Article
  • Open Access
23 Citations
12,104 Views
14 Pages

Reduced Anxiety in Forensic Inpatients after a Long-Term Intervention with Atlantic Salmon

  • Anita L. Hansen,
  • Gina Olson,
  • Lisbeth Dahl,
  • David Thornton,
  • Bjørn Grung,
  • Ingvild E. Graff,
  • Livar Frøyland and
  • Julian F. Thayer

26 November 2014

The aim of the present study was to investigate the effects of Atlantic salmon consumption on underlying biological mechanisms associated with anxiety such as heart rate variability (HRV) and heart rate (HR) as well as a measure of self-reported anxi...

  • Article
  • Open Access
39 Citations
10,502 Views
15 Pages

Vitamin D Status in Malaysian Men and Its Associated Factors

  • Kok-Yong Chin,
  • Soelaiman Ima-Nirwana,
  • Suraya Ibrahim,
  • Isa Naina Mohamed and
  • Wan Zurinah Wan Ngah

26 November 2014

Vitamin D insufficiency is a global health problem. The data on vitamin D status in Malaysian men is insufficient. This study aimed to investigate vitamin D status among Chinese and Malay men in Malaysia and its associating factors. A cross-sectional...

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Nutrients - ISSN 2072-6643