You are currently viewing a new version of our website. To view the old version click .

489 Results Found

  • Article
  • Open Access
18 Citations
6,122 Views
11 Pages

Effectiveness of Tele-Prescription of Therapeutic Physical Exercise in Patellofemoral Pain Syndrome during the COVID-19 Pandemic

  • Manuel Albornoz-Cabello,
  • Cristo J. Barrios-Quinta,
  • Ana M. Barrios-Quinta,
  • Isabel Escobio-Prieto,
  • María de los Angeles Cardero-Durán and
  • Luis Espejo-Antunez

The health crisis caused by COVID-19 has had a huge impact on the provision of physiotherapists’ services during the pandemic. Patellofemoral pain syndrome (PFPS) is a major health problem and one of the most common causes of pain in the front...

  • Systematic Review
  • Open Access
1,376 Views
19 Pages

Blockchains’ Impact on Enhancing Physical Activity, Rehabilitation, Sport, and Exercise-Based Therapeutics: A Systematic Review

  • Shahryar Eivazzadeh,
  • Sravan Mutyala,
  • Jaideep Chinthala,
  • Farnoosh Fotrousi and
  • Siamak Khatibi

27 March 2025

Blockchain technology is increasingly recognized as a promising solution for managing health-related data, particularly in promoting well-being through physical activity. This is becoming more significant as the Internet of Things (IoT) and sport mon...

  • Review
  • Open Access
1 Citations
7,780 Views
15 Pages

Therapeutic Physical Exercise for Dysmenorrhea: A Scoping Review

  • Philippine Rigal,
  • Salomé Bonnet,
  • Ágata Vieira,
  • Alice Carvalhais and
  • Sofia Lopes

Background: Dysmenorrhea affects many women of reproductive age. Physical exercise has been used as an effective intervention for pain reduction and to improve well-being. Physiotherapy, involving movement and exercise, can be effective in relieving...

  • Review
  • Open Access
7 Citations
3,163 Views
18 Pages

The Therapeutic Potential of Physical Exercise in Cancer: The Role of Chemokines

  • Glenda B. B. Buzaglo,
  • Guilherme D. Telles,
  • Rafaela B. Araújo,
  • Gilmar D. S. Junior,
  • Olivia M. Ruberti,
  • Marina L. V. Ferreira,
  • Sophie F. M. Derchain,
  • Felipe C. Vechin and
  • Miguel S. Conceição

23 December 2024

The global increase in cancer cases and mortality has been associated with inflammatory processes, in which chemokines play crucial roles. These molecules, a subfamily of cytokines, are essential for the migration, adhesion, interaction, and position...

  • Review
  • Open Access
39 Citations
17,523 Views
15 Pages

Systematic Review of Therapeutic Physical Exercise in Patients with Amyotrophic Lateral Sclerosis over Time

  • Laura Ortega-Hombrados,
  • Guadalupe Molina-Torres,
  • Alejandro Galán-Mercant,
  • Eduardo Sánchez-Guerrero,
  • Manuel González-Sánchez and
  • María Ruiz-Muñoz

Background: the main objective of this study was to analyze the potential short-, medium- and long-term effects of a therapeutic physical exercise (TFE) programme on the functionality of amyotrophic lateral sclerosis (ALS) patients, measured with the...

  • Review
  • Open Access
24 Citations
7,261 Views
14 Pages

Therapeutic Physical Exercise Post-Treatment in Breast Cancer: A Systematic Review of Clinical Practice Guidelines

  • Alicia del-Rosal-Jurado,
  • Rita Romero-Galisteo,
  • Manuel Trinidad-Fernández,
  • Manuel González-Sánchez,
  • Antonio Cuesta-Vargas and
  • Maria Ruiz-Muñoz

24 April 2020

Advances achieved in diagnosis and improvements in treatment for breast cancer have resulted in a favourable survival rate. Therapeutic physical exercise (TPE) is presented as an intervention strategy that seeks to improve the functional capabilities...

  • Article
  • Open Access
4 Citations
3,969 Views
13 Pages

Evaluation of Physical Therapy Interventions for Improving Musculoskeletal Pain and Quality of Life in Older Adults

  • Soraya Pacheco-da-Costa,
  • Concepción Soto-Vidal,
  • Victoria Calvo-Fuente,
  • María José Yuste-Sánchez,
  • Beatriz Sánchez-Sánchez and
  • Ángel Asúnsolo-del-Barco

Background: The ageing process may lead to functional limitations, musculoskeletal pain, and worsened quality of life. The aim of this paper is to evaluate two physical therapy interventions for reducing musculoskeletal pain and improving quality of...

  • Review
  • Open Access
35 Citations
11,432 Views
16 Pages

Childhood Obesity and Incorrect Body Posture: Impact on Physical Activity and the Therapeutic Role of Exercise

  • Valeria Calcaterra,
  • Luca Marin,
  • Matteo Vandoni,
  • Virginia Rossi,
  • Agnese Pirazzi,
  • Roberta Grazi,
  • Pamela Patané,
  • Giustino Simone Silvestro,
  • Vittoria Carnevale Pellino and
  • Ilaria Albanese
  • + 4 authors

Obesity is associated with various dysfunctions of the organism, including musculoskeletal problems. In this narrative review, we aim to consider postural problems in children and adolescents with obesity, focusing on the relationship with its negati...

  • Systematic Review
  • Open Access
1 Citations
1,201 Views
16 Pages

Therapeutic Exercise for Hospitalized Sarcopenic Patients: A Systematic Review and Meta-Analysis

  • Olivier Chan-Fook,
  • Javier Martin-Núñez,
  • Julia Raya-Benítez,
  • Alba Navas-Otero,
  • Irene Cabrera-Martos,
  • Marie Carmen Valenza and
  • Alejandro Heredia-Ciuró

12 September 2025

Sarcopenia is a progressive and generalized skeletal muscle disorder associated with an impairment of functional status, increasing dependency and mortality. The high prevalence among hospitalized patients has increased interest in active interventio...

  • Article
  • Open Access
2 Citations
4,013 Views
9 Pages

Efficacy of the Use of Wii Games in the Physical and Functional Training of the Elderly: Protocol of a Systematic Review

  • Andreia Lima,
  • Maria Teresa Moreira,
  • Maria Salomé Ferreira,
  • Vítor Parola,
  • Dárcio Tadeu Mendes,
  • Maria do Perpétuo Nóbrega and
  • Carla Fernandes

Background: Scientific and technological development has constituted a reality in the lives of populations, making it unimaginable to live without specific incentives that development has allowed. That said, given the increase in the longevity of peo...

  • Article
  • Open Access
11 Citations
4,874 Views
23 Pages

Effectiveness of a Physical Therapeutic Exercise Programme for Caregivers of Dependent Patients: A Pragmatic Randomised Controlled Trial from Spanish Primary Care

  • Federico Montero-Cuadrado,
  • Miguel Ángel Galán-Martín,
  • Javier Sánchez-Sánchez,
  • Enrique Lluch,
  • Agustín Mayo-Iscar and
  • Ántonio Cuesta-Vargas

Female family caregivers (FFCs) constitute one of the basic supports of socio-health care for dependence in developed countries. The care provided by FFCs may impact their physical and mental health, negatively affecting their quality of life. In ord...

  • Review
  • Open Access
18 Citations
8,673 Views
11 Pages

Therapeutic Exercise and Conservative Injection Treatment for Early Knee Osteoarthritis in Athletes: A Scoping Review

  • Lucrezia Tognolo,
  • Maria Chiara Maccarone,
  • Stefania De Trane,
  • Anna Scanu,
  • Stefano Masiero and
  • Pietro Fiore

3 January 2022

Background and Objectives: Recent evidence highlighted a higher prevalence of knee osteoarthritis (kOA) among young and former ex-professional athletes. Although the practice of a highly demanding sport is considered a predisposing factor for the kne...

  • Article
  • Open Access
11 Citations
4,761 Views
11 Pages

Does the Addition of Pain Neurophysiology Education to a Therapeutic Exercise Program Improve Physical Function in Women with Fibromyalgia Syndrome? Secondary Analysis of a Randomized Controlled Trial

  • Luis Ceballos-Laita,
  • María Teresa Mingo-Gómez,
  • Elena Estébanez-de-Miguel,
  • Elena Bueno-Gracia,
  • Francisto José Navas-Cámara,
  • Zoraida Verde-Rello,
  • Ana Fernández-Araque and
  • Sandra Jiménez-del-Barrio

7 June 2021

Therapeutic exercise (TE) is one of the most investigated approaches for the management of FMS. Pain neurophysiology education (PNE) helps toward understanding the pain condition, leading to maladaptive pain cognitions and coping strategies in patien...

  • Review
  • Open Access
13 Citations
18,036 Views
20 Pages

Physical Exercise as a Therapeutic Approach in Gastrointestinal Diseases

  • Juliana Soares Severo,
  • Alda Cássia Alves da Silva,
  • Brenda Lois Barros dos Santos,
  • Thiago Sousa Reinaldo,
  • Aureliano Machado de Oliveira,
  • Rodrigo Soares Pereira Lima,
  • Francisco Leonardo Torres-Leal,
  • Armênio Aguiar dos Santos and
  • Moisés Tolentino Bento da Silva

3 March 2025

Background/Objectives: Physical exercise can have significant consequences for the gastrointestinal tract, which is why there have been studies into its influence on the treatment of conditions such as colorectal cancer, inflammatory bowel diseases (...

  • Conference Report
  • Open Access
63 Citations
7,696 Views
11 Pages

Novel Strategies for Cancer Treatment: Highlights from the 55th IACR Annual Conference

  • Sara Charmsaz,
  • Denis M. Collins,
  • Antoinette S. Perry and
  • Maria Prencipe

7 August 2019

While conventional cancer treatments, such as surgery, radiotherapy and chemotherapy, have been combined for decades in an effort to treat cancer patients, the emergence of novel fields of cancer research have led to a renewed interest in combining c...

  • Review
  • Open Access
300 Views
25 Pages

18 December 2025

Background/Objectives: Intensive care units (ICU) immobility and weakness impair recovery, yet practice for Physical Therapist (PT)-led therapeutic exercise and mobility varies in definitions, dosing, safety, and documentation, which limits comparabi...

  • Review
  • Open Access
38 Citations
6,273 Views
19 Pages

15 December 2022

In the current global scenario, many COVID-19 survivors present a severe deterioration in physical strength, respiratory function, and quality of life due to persistent symptoms and post-acute consequences of SARS-CoV-2 infection. These alterations a...

  • Article
  • Open Access
2 Citations
4,204 Views
24 Pages

Lumbar Paravertebral Muscle Pain Management Using Kinesitherapy and Electrotherapeutic Modalities

  • Sînziana Călina Silişteanu,
  • Elisabeta Antonescu,
  • Lavinia Duică,
  • Maria Totan,
  • Andrei Ionuţ Cucu and
  • Andrei Ioan Costea

Background: Low back pain is considered a public health problem internationally. Low back pain is a cause of disability that occurs in adolescents and causes negative effects in adults as well. The work environment and physical and psychosocial facto...

  • Review
  • Open Access
15 Citations
4,972 Views
24 Pages

Advancing Alzheimer’s Therapeutics: Exploring the Impact of Physical Exercise in Animal Models and Patients

  • Jesús Andrade-Guerrero,
  • Paola Rodríguez-Arellano,
  • Nayeli Barron-Leon,
  • Erika Orta-Salazar,
  • Carlos Ledesma-Alonso,
  • Sofía Díaz-Cintra and
  • Luis O. Soto-Rojas

27 October 2023

Alzheimer’s disease (AD) is the main neurodegenerative disorder characterized by several pathophysiological features, including the misfolding of the tau protein and the amyloid beta (Aβ) peptide, neuroinflammation, oxidative stress, synap...

  • Systematic Review
  • Open Access
14 Citations
3,961 Views
21 Pages

Therapeutic Physical Exercise Programs in the Context of NASH Cirrhosis and Liver Transplantation: A Systematic Review

  • Marwin A. Farrugia,
  • Sebastien Le Garf,
  • Andrea Chierici,
  • Thierry Piche,
  • Philippe Gual,
  • Antonio Iannelli and
  • Rodolphe Anty

23 February 2023

In recent years, various physical exercise interventions have been developed with a view to reducing comorbidity and morbidity rates among patients with chronic diseases. Regular physical exercise has been shown to reduce hypertension and mortality i...

  • Review
  • Open Access
12 Citations
8,061 Views
23 Pages

Therapeutics That Can Potentially Replicate or Augment the Anti-Aging Effects of Physical Exercise

  • Adriana De Sousa Lages,
  • Valentim Lopes,
  • João Horta,
  • João Espregueira-Mendes,
  • Renato Andrade and
  • Alexandre Rebelo-Marques

1 September 2022

Globally, better health care access and social conditions ensured a significant increase in the life expectancy of the population. There is, however, a clear increase in the incidence of age-related diseases which, besides affecting the social and ec...

  • Review
  • Open Access
2,059 Views
24 Pages

23 August 2025

For a few decades, Type 2 Diabetes (T2D) has been recognized as a worldwide public health issue. T2D relies on systemic insulin resistance leading to Beta cell dysfunction. Nowadays, lifestyle modifications, such as improving eating habits and increa...

  • Article
  • Open Access
1 Citations
2,254 Views
12 Pages

Community-based group physical activity programs promote exercise opportunities for older people. The aim of this study was to examine the short-term, new participant effect after joining Vitality, a community-based group physical activity program av...

  • Systematic Review
  • Open Access
1 Citations
10,862 Views
17 Pages

Effects of Exercise-Based Rehabilitation on Lumbar Degenerative Disc Disease: A Systematic Review

  • Shirin Aali,
  • Farhad Rezazadeh,
  • Fariborz Imani,
  • Mahsa Nabati Sefidekhan,
  • Georgian Badicu,
  • Luca Poli,
  • Francesco Fischetti,
  • Stefania Cataldi and
  • Gianpiero Greco

7 August 2025

Background: This systematic review evaluates the efficacy of rehabilitation-focused exercise interventions for lumbar degenerative disc disease (DDD), a leading cause of chronic low back pain. Methods: Following PRISMA guidelines, a comprehensive sea...

  • Editorial
  • Open Access
2 Citations
5,691 Views
12 Pages

The “Journal of Functional Morphology and Kinesiology” Journal Club Series: Highlights on Recent Papers in Corrective Exercise

  • Antonino Bianco,
  • Silvio Lorenzetti,
  • Jan Seiler,
  • Heiliane de Brito Fontana,
  • Walter Herzog,
  • Gessica Aline Silvano,
  • Heron Baptista de Oliveira Medeiros and
  • Giuseppe Musumeci

We are glad to introduce the Journal Club of Volume Five, fourth Issue. This edition is focused on relevant studies published in the last few years in the field of corrective exercise, chosen by our Editorial Board members and their colleagues. We ho...

  • Article
  • Open Access
2 Citations
3,264 Views
11 Pages

Non-Invasive Radiofrequency Diathermy Neuromodulation Added to Supervised Therapeutic Exercise in Patellofemoral Pain Syndrome: A Single Blind Randomized Controlled Trial with Six Months of Follow-Up

  • Manuel Albornoz-Cabello,
  • Alfonso Javier Ibáñez-Vera,
  • Cristo Jesús Barrios-Quinta,
  • Luis Espejo-Antúnez,
  • Inmaculada Carmen Lara-Palomo and
  • María de los Ángeles Cardero-Durán

The evidence-based treatment of patellofemoral pain (PFP) suggests that therapeutic exercise (TE) focused on improving muscle strength and motor control be the main conservative treatment. Recent research determined that the success of the TE approac...

  • Review
  • Open Access
5 Citations
10,241 Views
29 Pages

The Hidden Dangers of Sedentary Living: Insights into Molecular, Cellular, and Systemic Mechanisms

  • Daniel Guerreiro Diniz,
  • João Bento-Torres,
  • Victor Oliveira da Costa,
  • Josilayne Patricia Ramos Carvalho,
  • Alessandra Mendonça Tomás,
  • Thaís Cristina Galdino de Oliveira,
  • Fernanda Cabral Soares,
  • Liliane Dias e Dias de Macedo,
  • Naina Yuki Vieira Jardim and
  • Natáli Valim Oliver Bento-Torres
  • + 3 authors

6 October 2024

With the aging of the global population, neurodegenerative diseases are emerging as a major public health issue. The adoption of a less sedentary lifestyle has been shown to have a beneficial effect on cognitive decline, but the molecular mechanisms...

  • Article
  • Open Access
6 Citations
5,844 Views
22 Pages

Condylar Remodeling and Skeletal Changes Following Occlusal Splint and Manual Therapy: A Cone Beam Computed Tomography Study in Temporomandibular Disorders

  • Manuela Tăut,
  • Ioan Barbur,
  • Mihaela Hedeșiu,
  • Alina Ban,
  • Daniel Leucuța,
  • Marius Negucioiu,
  • Smaranda Dana Buduru and
  • Aranka Ilea

19 September 2024

Background: Temporomandibular disorders (TMD) may be associated with degenerative disease of temporomandibular joint (TMJ), such as condyle erosion and subchondral cysts. Occlusal splint and cranio-mandibular manual therapy, or combined therapy, is r...

  • Article
  • Open Access
3 Citations
35,740 Views
12 Pages

30 October 2024

Telomere length is an index of cellular aging. Healthy lifestyles are associated with reduced oxidative stress and longer telomeres, whereas unhealthy behaviors are related to shorter telomeres and greater biological aging. This investigation was des...

  • Article
  • Open Access
1 Citations
4,053 Views
12 Pages

18 December 2024

Background/Objectives: Venous ulcers are the most common type of ulcerated wounds in the lower limbs and result from chronic venous insufficiency. The treatment of venous ulcers is multidisciplinary, with physiotherapy intervention serving as an adju...

  • Article
  • Open Access
5 Citations
10,139 Views
13 Pages

Electromyographic Evaluation of Specific Elastic Band Exercises Targeting Neck and Shoulder Muscle Activation

  • Ying Gao,
  • Lars A. Kristensen,
  • Thomas S. Grøndberg,
  • Mike Murray,
  • Gisela Sjøgaard and
  • Karen Søgaard

21 January 2020

Background: Specific strength training at a high intensity is effective in reducing work related neck/shoulder pain. However, it remains to be documented as to which exercises most specifically target neck and shoulder muscles at high activation leve...

  • Article
  • Open Access
40 Citations
9,238 Views
13 Pages

Type 2 diabetes mellitus (T2DM) is significantly associated with osteoarthritis (OA). This study investigated the effects of two resistance exercise approaches on glycated hemoglobin (HbA1c) level and function performance. Enrolled were 70 older pati...

  • Article
  • Open Access
5 Citations
2,815 Views
12 Pages

Efficacy of Exercise on Postneedling Soreness: A Randomized Controlled Trial

  • Nicola Sante Diciolla,
  • Celia Pérez-Clemente,
  • Marta Cámara-Caballero,
  • Alberto Matienzo-Barreto,
  • Alba Real-Rodríguez and
  • María Torres-Lacomba

25 November 2021

This study aimed to investigate the efficacy of concentric, eccentric, and isometric exercise protocols on the postneedling soreness (PNS) after the dry needling (DN) of latent myofascial trigger points (MTrP) in the medial gastrocnemius muscle. A ra...

  • Article
  • Open Access
976 Views
19 Pages

Metabolic, Hematological, and Functional Health in Adults with Down Syndrome and Significance of Parental Health Literacy: A Cross-Sectional Study

  • Petra Rajkovic Vuletic,
  • Marijana Geets-Kesic,
  • Anamarija Jurcev-Savicevic,
  • Nurjanah Nurjanah and
  • Barbara Gilic

Background/Objectives: The evaluation of metabolic and physiological health indicators in people with Down syndrome (DS) is crucial, since these people are more prone to metabolic problems. However, there is limited scientific evidence regarding the...

  • Article
  • Open Access
76 Citations
19,957 Views
22 Pages

Pain Neuroscience Education and Physical Therapeutic Exercise for Patients with Chronic Spinal Pain in Spanish Physiotherapy Primary Care: A Pragmatic Randomized Controlled Trial

  • Miguel Angel Galan-Martin,
  • Federico Montero-Cuadrado,
  • Enrique Lluch-Girbes,
  • María Carmen Coca-López,
  • Agustín Mayo-Iscar and
  • Antonio Cuesta-Vargas

22 April 2020

Chronic musculoskeletal pain affects more than 20% of the population, leading to high health care overload and huge spending. The prevalence is increasing and negatively affects both physical and mental health, being one of the leading causes of disa...

  • Review
  • Open Access
29 Citations
4,365 Views
16 Pages

Physical Exercise Potentially Targets Epicardial Adipose Tissue to Reduce Cardiovascular Disease Risk in Patients with Metabolic Diseases: Oxidative Stress and Inflammation Emerge as Major Therapeutic Targets

  • Thembeka A. Nyawo,
  • Carmen Pheiffer,
  • Sithandiwe E. Mazibuko-Mbeje,
  • Sinenhlanhla X. H. Mthembu,
  • Tawanda M. Nyambuya,
  • Bongani B. Nkambule,
  • Hanél Sadie-Van Gijsen,
  • Hans Strijdom,
  • Luca Tiano and
  • Phiwayinkosi V. Dludla

4 November 2021

Excess epicardial adiposity, within a state of obesity and metabolic syndrome, is emerging as an important risk factor for the development of cardiovascular diseases (CVDs). Accordingly, increased epicardial fat thickness (EFT) implicates the exacerb...

  • Article
  • Open Access
4,019 Views
12 Pages

Analysis of Dry Needling Combined with an Exercise Program in the Treatment of Knee Osteoarthritis: A Randomized Clinical Trial

  • Aida Agost-González,
  • Isabel Escobio-Prieto,
  • Cristo Jesús Barrios-Quinta,
  • María de los Ángeles Cardero-Durán,
  • Luis Espejo-Antúnez and
  • Manuel Albornoz-Cabello

26 November 2024

Background: Therapeutic exercise is recommended for people with knee osteoarthritis (OA), although it could be complemented with other treatments such as dry needling (DN). The purpose of this study was to evaluate and compare the resulting data on p...

  • Article
  • Open Access
4 Citations
4,155 Views
15 Pages

Barriers and Facilitators for Therapeutic Green Exercise in Patients with Chronic Conditions: A Qualitative Focus Group Study

  • Aristi Tsokani,
  • Theodoros Dimopoulos,
  • Evangelos Vourazanis,
  • Nikolaos Strimpakos,
  • Evdokia Billis,
  • Garyfallia Pepera and
  • Eleni Kapreli

7 September 2023

Background: Exercise has indisputable advantages for people with chronic conditions. Engaging in physical activity within natural environments, known as green exercise, contributes to both physical and mental well-being. The aim of this study was to...

  • Opinion
  • Open Access
10 Citations
4,194 Views
11 Pages

13 February 2023

The strong benefits of exercise, in addition to the development of both the therapeutic applications of physical activity and molecular biology tools, means that it has become very important to explore the underlying molecular patterns linking exerci...

  • Feature Paper
  • Review
  • Open Access
9 Citations
5,572 Views
24 Pages

Incorporating Therapeutic Education and Exercise in Migraine Management: A Biobehavioral Approach

  • Roy La Touche,
  • Arão Belitardo de Oliveira,
  • Alba Paris-Alemany and
  • Álvaro Reina-Varona

21 October 2024

The main objective was to perform a description of the potential biobehavioral factors that influence disability in patients with migraines and develop a multimodal physiotherapy treatment proposal incorporating therapeutic education and exercise pre...

  • Review
  • Open Access
18 Citations
6,218 Views
26 Pages

Circulating Extracellular Vesicles: The Missing Link between Physical Exercise and Depression Management?

  • Edna Soares,
  • Julie Reis,
  • Mariana Rodrigues,
  • Carlos Fontes Ribeiro and
  • Frederico C. Pereira

Depression is associated with an increased risk of aging-related diseases. It is also seemingly a common psychological reaction to pandemic outbreaks with forced quarantines and lockdowns. Thus, depression represents, now more than ever, a major glob...

  • Review
  • Open Access
39 Citations
23,940 Views
17 Pages

The Role of Physical Exercise in Chronic Musculoskeletal Pain: Best Medicine—A Narrative Review

  • Hortensia De la Corte-Rodriguez,
  • Juan M. Roman-Belmonte,
  • Cristina Resino-Luis,
  • Jorge Madrid-Gonzalez and
  • Emerito Carlos Rodriguez-Merchan

18 January 2024

The aim of this paper is to provide a narrative review of the effects of physical exercise in the treatment of chronic musculoskeletal pain. Physical inactivity and sedentary behavior are associated with chronic musculoskeletal pain and can aggravate...

  • Review
  • Open Access
19 Citations
35,201 Views
19 Pages

12 August 2022

Therapeutic exercise is widely considered a first line fundamental treatment option for managing tendinopathies. As the Achilles tendon is critical for locomotion, chronic Achilles tendinopathy can have a substantial impact on an individual’s a...

  • Review
  • Open Access
5 Citations
11,679 Views
15 Pages

Is It Possible to Train the Endothelium?—A Narrative Literature Review

  • Karolina Biernat,
  • Natalia Kuciel,
  • Justyna Mazurek and
  • Katarzyna Hap

10 May 2024

This review provides an overview of current knowledge regarding the adaptive effects of physical training on the endothelium. The endothelium plays a crucial role in maintaining the health of vessel walls and regulating vascular tone, structure, and...

  • Review
  • Open Access
5 Citations
4,364 Views
8 Pages

Physical Exercise-Induced FGF-21 to Fight Obesity: An Update Review

  • Bruno Vecchiatto,
  • Thiago Lucas de Castro,
  • Cynthia R. Muller,
  • Anna Karenina Azevedo-Martins and
  • Fabiana S. Evangelista

11 November 2022

Fibroblast growth factor 21 (FGF-21) is a protein that is involved in the regulation of glucose, lipids, and energy metabolism. To act on target tissues, endocrine FGF-21 binds preferably to FGF receptor 1 (FGFR1) in the presence of the coreceptor na...

  • Review
  • Open Access
33 Citations
14,925 Views
24 Pages

The Impact of Exercise on Immunity, Metabolism, and Atherosclerosis

  • Ulrike Meyer-Lindemann,
  • Aldo Moggio,
  • Alexander Dutsch,
  • Thorsten Kessler and
  • Hendrik B. Sager

8 February 2023

Physical exercise represents an effective preventive and therapeutic strategy beneficially modifying the course of multiple diseases. The protective mechanisms of exercise are manifold; primarily, they are elicited by alterations in metabolic and inf...

  • Review
  • Open Access
36 Citations
8,454 Views
29 Pages

Although many cardiovascular (CVD) medications, such as antithrombotics, statins, and antihypertensives, have been identified to treat atherosclerosis, at most, many of these therapeutic agents only delay its progression. A growing body of evidence s...

  • Review
  • Open Access
6 Citations
4,053 Views
35 Pages

The Influence of Irisin on Selected Organs—The Liver, Kidneys, and Lungs: The Role of Physical Exercise

  • Maria Ciałowicz,
  • Marek Woźniewski,
  • Eugenia Murawska-Ciałowicz and
  • Piotr Dzięgiel

8 August 2025

In recent years, irisin has garnered significant interest among researchers. It is a myokine released by skeletal muscles during physical exercise. Its expression occurs not only in skeletal muscles but also in other organs such as the liver, kidneys...

  • Systematic Review
  • Open Access
888 Views
20 Pages

Effects of Multicomponent Exercise on Pain and Biopsychosocial Outcomes in Adults with Cancer: A Systematic Review

  • Leidy Tatiana Ordoñez-Mora,
  • Juan Fernando Gómez-Gómez,
  • Mateo Marquez-Bustamante,
  • Ilem D. Rosero,
  • Giovanna Patricia Rivas-Tafurt and
  • Jose Luis Estela-Zape

9 November 2025

Background/Objective: Cancer significantly impairs physical function and quality of life. Exercise has gained recognition as a therapeutic strategy; however, its long-term efficacy in terms of multidimensional outcomes in patients with cancer remains...

  • Article
  • Open Access
1 Citations
3,403 Views
14 Pages

22 July 2024

The loss of vestibular and motor function can occur naturally with aging. Vestibular physiotherapy exercises (VE) specifically address vestibular rehabilitation to reduce imbalances and improve physical condition, like therapeutic exercise (TE). Duri...

of 10