You are currently viewing a new version of our website. To view the old version click .

406 Results Found

  • Article
  • Open Access
10 Citations
3,294 Views
12 Pages

Regular Oral Health Management Improved Oral Function of Outpatients with Oral Hypofunction in Dental Hospital: A Longitudinal Study

  • Yukiko Hatanaka,
  • Junichi Furuya,
  • Yuji Sato,
  • Risako Taue,
  • Yoshiki Uchida,
  • Toshiharu Shichita and
  • Tokiko Osawa

This longitudinal study aimed to clarify the impact of regular oral health management for oral hypofunction on the oral function of older dental outpatients. The 68 participants enrolled in this study were older dental outpatients (mean age 78.5 &plu...

  • Review
  • Open Access
1,905 Views
10 Pages

Chewing Matters: Masticatory Function, Oral Microbiota, and Gut Health in the Nutritional Management of Aging

  • Monia Lettieri,
  • Alessio Rosa,
  • Fabrizio Spataro,
  • Giovanni Capria,
  • Paolo Barnaba,
  • Marco Gargari and
  • Mirko Martelli

30 July 2025

Aging is a multifactorial process that affects various physiological functions, including masticatory performance, which is crucial for oral health and nutritional well-being. Impaired masticatory function, often due to factors such as tooth loss, re...

  • Review
  • Open Access
13 Citations
9,151 Views
19 Pages

Oral Health Management and Rehabilitation for Patients with Oral Cancer: A Narrative Review

  • Yuhei Matsuda,
  • Ruwan D. Jayasinghe,
  • Hui Zhong,
  • Shinichi Arakawa and
  • Takahiro Kanno

Surgery is the current first choice for oral cancer treatment. Intensity-modulated radiation therapy, molecular targeted drugs, and immune checkpoint inhibitors are still used as adjuvant therapy for advanced cancer. In addition, postoperative rehabi...

  • Article
  • Open Access
3 Citations
2,427 Views
9 Pages

The Association between Oral Health Management and the Functional Independence Measure Scores at the Time of Admission of Inpatients to a Convalescent Hospital

  • Ryuzo Hara,
  • Naoki Todayama,
  • Tomohiro Tabata,
  • Miki Kuwazawa,
  • Tomoko Mukai,
  • Yukiko Hatanaka,
  • Shouji Hironaka,
  • Nobuyuki Kawate and
  • Junichi Furuya

18 October 2023

Many older patients admitted to convalescent hospitals present with impaired oral function, which is an important function of daily life. This study aimed to investigate the actual status of the oral healthcare needs of inpatients in a convalescent h...

  • Article
  • Open Access
13 Citations
4,130 Views
18 Pages

Preventive Effects of Sustainable and Developmental Perioperative Oral Management Using the “Oral Triage” System on Postoperative Pneumonia after Cancer Surgery

  • Hideki Sekiya,
  • Yasuhiro Kurasawa,
  • Kosuke Kaneko,
  • Ken-ichiro Takahashi,
  • Yutaka Maruoka,
  • Yukihiro Michiwaki,
  • Yoshimasa Takeda and
  • Ryoichi Ochiai

Perioperative oral management is widely recognized in the healthcare system of Japan. Conventionally, the surgeon refers patients with oral problems to a dental or oral surgery clinic in the hospital. However, frequent in-house referrals were found t...

  • Article
  • Open Access
7 Citations
3,554 Views
12 Pages

Dental Hygienists’ Practice in Perioperative Oral Care Management According to the Japanese Dental Hygienists Survey 2019

  • Yoshiaki Nomura,
  • Yuki Ohara,
  • Yuko Yamamoto,
  • Ayako Okada,
  • Noriyasu Hosoya,
  • Nobuhiro Hanada and
  • Noriko Takei

Perioperative oral care management is effective in the prevention of postoperative complications, and dental hygienists play an important role. The aim of this study was to elucidate the practice and substantial role of dental hygienists in periopera...

  • Article
  • Open Access
38 Citations
4,974 Views
10 Pages

Associations between Oral Hypofunction Tests, Age, and Sex

  • Yukiko Hatanaka,
  • Junichi Furuya,
  • Yuji Sato,
  • Yoshiki Uchida,
  • Toshiharu Shichita,
  • Noboru Kitagawa and
  • Tokiko Osawa

Oral function declines in older individuals due to disease and age-related changes, making them vulnerable to oral and physical frailty. Therefore, it is important to manage the decline in oral function in older outpatients. Oral hypofunction is diag...

  • Article
  • Open Access
3 Citations
1,973 Views
11 Pages

Systemic and Oral Characteristics of Convalescent Inpatients Requiring Oral-Health Management by a Dental Specialist during Hospitalization

  • Naoki Todayama,
  • Ryuzo Hara,
  • Tomohiro Tabata,
  • Yukiko Hatanaka,
  • Tomoko Mukai,
  • Mika Someya,
  • Miki Kuwazawa,
  • Hiroyuki Suzuki,
  • Shouji Hironaka and
  • Nobuyuki Kawate
  • + 1 author

Older adults often experience poor oral functions, hindering rehabilitation post-acute disease treatment. However, characteristics of hospitalized patients who would benefit from professional oral-health management (POHM) have not been clarified. The...

  • Article
  • Open Access
11 Citations
2,744 Views
10 Pages

Changes in Nutrition-Intake Method and Oral Health through a Multidisciplinary Team Approach in Malnourished Older Patients Admitted to an Acute Care Hospital

  • Hiroyuki Suzuki,
  • Junichi Furuya,
  • Kazuharu Nakagawa,
  • Rena Hidaka,
  • Ayako Nakane,
  • Kanako Yoshimi,
  • Yukue Shimizu,
  • Keiko Saito,
  • Yasuhiro Itsui and
  • Haruka Tohara
  • + 2 authors

Malnourished older inpatients referred to a nutrition support team (NST) usually receive multidisciplinary oral health management during NST intervention. However, the effects of multidisciplinary oral health management on the nutrition-intake method...

  • Article
  • Open Access
19 Citations
5,160 Views
11 Pages

Association between Improvement of Oral Health, Swallowing Function, and Nutritional Intake Method in Acute Stroke Patients

  • Michiyo Aoyagi,
  • Junichi Furuya,
  • Chiaki Matsubara,
  • Kanako Yoshimi,
  • Ayako Nakane,
  • Kazuharu Nakagawa,
  • Motoki Inaji,
  • Yuji Sato,
  • Haruka Tohara and
  • Shunsuke Minakuchi
  • + 1 author

Stroke and poor oral health are common in older people, and the brain injuries associated with stroke are often accompanied by a decline in oral function. In this study, we investigated the characteristics of stroke patients who could not recover ora...

  • Review
  • Open Access
12 Citations
20,909 Views
18 Pages

Candida Infection Associated with Salivary Gland—A Narrative Review

  • Soo-Min Ok,
  • Donald Ho,
  • Tyler Lynd,
  • Yong-Woo Ahn,
  • Hye-Min Ju,
  • Sung-Hee Jeong and
  • Kyounga Cheon

30 December 2020

Candida species are common global opportunistic pathogens that could repeatedly and chronically cause oral mucosa infection and create an inflammatory environment, leading to organ dysfunction. Oral Candida infections may cause temporary or permanent...

  • Article
  • Open Access
9 Citations
3,637 Views
10 Pages

Association between Dementia Severity and Oral Hygiene Management Issues in Older Adults with Alzheimer’s Disease: A Cross-Sectional Study

  • Maki Shirobe,
  • Ayako Edahiro,
  • Keiko Motokawa,
  • Shiho Morishita,
  • Yuki Ohara,
  • Yoshiko Motohashi,
  • Masanori Iwasaki,
  • Yutaka Watanabe and
  • Hirohiko Hirano

Oral hygiene management issues vary across types and clinical stages of dementia. We aimed to clarify the issues related to oral hygiene management in older adults with Alzheimer’s disease (AD) according to stages defined by the Functional Asse...

  • Review
  • Open Access
11 Citations
6,835 Views
28 Pages

10 June 2020

Health-related behavior based on diet is an important determinant of oral health in independent elderly. Aging impairs senses, mastication, oral status, and function, causing nutritional needs and diet insufficiencies that contribute to a vicious cir...

  • Review
  • Open Access
4 Citations
4,751 Views
24 Pages

The Oral Microbial Ecosystem in Age-Related Xerostomia: A Critical Review

  • Xiao-Meng Pei,
  • Lian-Xin Zhou,
  • Man-Wah Tsang,
  • William Chi-Shing Tai and
  • Sze-Chuen Cesar Wong

28 November 2024

Xerostomia is a widespread condition among the elderly, impacting as many as 50% of individuals within this demographic. This review aims to analyze the association between age-related xerostomia and the oral microbial ecosystem. Xerostomia not only...

  • Review
  • Open Access
1,586 Views
25 Pages

2 July 2025

Xerostomia significantly compromises oral comfort, mucosal integrity, and denture retention. While topical therapies such as oral gels are commonly used to manage symptoms, their effectiveness remains limited due to an inability to replicate the comp...

  • Article
  • Open Access
1 Citations
1,884 Views
10 Pages

Oral Health Assessment for Older Residents in Long-Term Care Facilities Using Video Recording by a Mobile Electronic Device

  • Kazuki Ako,
  • Hiroyuki Suzuki,
  • Masataka Watanabe,
  • Hosei Suzuki,
  • Kae Namikawa,
  • Mana Hirayama,
  • Kunihito Yamane,
  • Tomoko Mukai,
  • Yukiko Hatanaka and
  • Junichi Furuya

17 October 2024

Background/Objectives: Many older adults who require long-term care need oral health management. However, access to dental care is limited, and connecting older patients with dental professionals is a future challenge. Therefore, the development of a...

  • Case Report
  • Open Access
44 Citations
7,263 Views
11 Pages

Oral complications of cancer therapy, such as oral dryness, dysphagia, and taste alteration, are associated with a negative impact in the quality of life of the patients. Few supportive care measures are available for such complications. This case se...

  • Article
  • Open Access
18 Citations
163 Views
11 Pages

Survey of Current Practice Patterns in the Management of Frontal Sinus Fractures

  • Kevin J. Choi,
  • Bora Chang,
  • Charles R. Woodard,
  • David B. Powers,
  • Jeffrey R. Marcus and
  • Liana Puscas

The management of frontal sinus fractures has evolved in the endoscopic era. The development of functional endoscopic sinus surgery (FESS) has been incorporated into management algorithms proposed by otolaryngologists, but the extent of its influence...

  • Review
  • Open Access
15 Citations
5,365 Views
19 Pages

The Link between Stroke Risk and Orodental Status—A Comprehensive Review

  • Shahriar Shahi,
  • Mehdi Farhoudi,
  • Solmaz Maleki Dizaj,
  • Simin Sharifi,
  • Saeed Sadigh-Eteghad,
  • Khang Wen Goh,
  • Long Chiau Ming,
  • Jagjit Singh Dhaliwal and
  • Sara Salatin

2 October 2022

One of the primary causes of disability and mortality in the adult population worldwide is stroke. A person’s general health is significantly impacted by their oral and dental health. People who have poor oral health are more susceptible to con...

  • Article
  • Open Access
13 Citations
3,741 Views
11 Pages

Factors Related to Oral Intake of Food by Hospitalized Patients with Malnutrition under the Care of a Nutrition Support Team

  • Junichi Furuya,
  • Hiroyuki Suzuki,
  • Rena Hidaka,
  • Kazuharu Nakagawa,
  • Kanako Yoshimi,
  • Ayako Nakane,
  • Kohei Yamaguchi,
  • Yukue Shimizu,
  • Yasuhiro Itsui and
  • Keiko Saito
  • + 3 authors

This study aimed to evaluate the role of the general condition and oral health status in determining the primary nutritional route and suitable food form for oral ingestion among malnourished inpatients. This cross-sectional study included 255 inpati...

  • Review
  • Open Access
19 Citations
3,789 Views
25 Pages

Saliva as Biomarker for Oral and Chronic Degenerative Non-Communicable Diseases

  • Michele Basilicata,
  • Massimo Pieri,
  • Giulia Marrone,
  • Eleonora Nicolai,
  • Manuela Di Lauro,
  • Vincenza Paolino,
  • Flaminia Tomassetti,
  • Ilaria Vivarini,
  • Patrizio Bollero and
  • Sergio Bernardini
  • + 1 author

Saliva is a very complex fluid and it is essential to maintain several physiological processes and functions, including oral health, taste, digestion and immunological defenses. Saliva composition and the oral microbiome can be influenced by several...

  • Review
  • Open Access
59 Citations
20,956 Views
20 Pages

A Review on Xerostomia and Its Various Management Strategies: The Role of Advanced Polymeric Materials in the Treatment Approaches

  • Afroditi Kapourani,
  • Konstantinos N. Kontogiannopoulos,
  • Alexandra-Eleftheria Manioudaki,
  • Athanasios K. Poulopoulos,
  • Lazaros Tsalikis,
  • Andreana N. Assimopoulou and
  • Panagiotis Barmpalexis

22 February 2022

The medical term xerostomia refers to the subjective sensation of oral dryness. The etiology seems to be multifactorial with the most frequently reported causes being the use of xerostomic medications, neck and head radiation, and systematic diseases...

  • Article
  • Open Access
2,149 Views
9 Pages

Factors Related to Oral Problems in Patients with Prolonged Disorders of Consciousness in Long-Term Care: A Cross-Sectional Study

  • Kanako Yoshimi,
  • Kazuharu Nakagawa,
  • Kohei Yamaguchi,
  • Ayako Nakane,
  • Masaharu Hayashi,
  • Rie Miyata,
  • Yumi Chiba and
  • Haruka Tohara

Factors influencing oral problems, such as malocclusion and oral motor dysfunction, in patients with prolonged disorders of consciousness (DOC) remain unclear. This study aimed to clarify the relationship between oral problems and physical function,...

  • Case Report
  • Open Access
277 Views
23 Pages

28 October 2025

Background: Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity, often necessitating extensive surgical resection. Such interventions may result in complex intraoral defects requiring immediate reconstruction to resto...

  • Feature Paper
  • Review
  • Open Access
204 Citations
19,934 Views
17 Pages

Poor Oral Health as a Determinant of Malnutrition and Sarcopenia

  • Domenico Azzolino,
  • Pier Carmine Passarelli,
  • Paolo De Angelis,
  • Giovan Battista Piccirillo,
  • Antonio D’Addona and
  • Matteo Cesari

29 November 2019

Aging is accompanied by profound changes in many physiological functions, leading to a decreased ability to cope with stressors. Many changes are subtle, but can negatively affect nutrient intake, leading to overt malnutrition. Poor oral health may a...

  • Article
  • Open Access
2,365 Views
14 Pages

13 March 2025

Background/Objectives: Oral intake and secretions need to be assessed separately, especially in patients with tracheal tubes, as they are vital for dysphagia treatment and may require different management strategies. This study aims to validate the I...

  • Communication
  • Open Access
5 Citations
3,220 Views
7 Pages

As function preservation cancer therapy, targeted radiation therapies have been developed for the quality of life of cancer patients. However, preclinical animal studies evaluating the safety and efficacy of targeted radiation therapy is challenging...

  • Review
  • Open Access
3 Citations
8,717 Views
13 Pages

Oral Hygiene and Cardiovascular Health

  • Md S. Zaman,
  • S. M. Golam Alam and
  • Mohammed S. Razzaque

3 April 2025

The human oral microbiome plays a vital role in maintaining oral and systemic health. This diverse microbial community includes over 700 bacterial species, some of which are implicated in developing systemic diseases, particularly cardiovascular dise...

  • Article
  • Open Access
10 Citations
2,720 Views
9 Pages

Chemosensory Function in Burning Mouth Syndrome a Comparative Cross-Sectional Study

  • Pia López-Jornet,
  • Yolanda Collado,
  • Alfonso Zambudio,
  • Eduardo Pons-Fuster,
  • Candela Castillo Felipe and
  • Asta Tvarijonaviciute

25 February 2021

Taste and smell are considered to be functions that contribute to the maintenance of good nutritional status. The present study evaluates taste and smell function in patients with burning mouth syndrome (BMS) versus a control group. A cross-sectional...

  • Review
  • Open Access
28 Citations
5,810 Views
14 Pages

29 April 2023

Older adults who face systemic health issues and lack adequate social support are at risk for oral health deterioration. How rapidly such changes take place depends on the severity of their medical condition and their ability to access oral health se...

  • Article
  • Open Access
2 Citations
3,075 Views
11 Pages

13 December 2023

This article presents the outcomes of prosthetic oral rehabilitation using CAD/CAM telescopic bar overdentures in patients with oral cancer (n = 3), severe facial trauma (n = 2), or various syndromes (n = 1), all suffering from severe tissue deficits...

  • Review
  • Open Access
24 Citations
7,053 Views
13 Pages

Complementary Feeding in Preterm Infants: A Systematic Review

  • Nadia Liotto,
  • Francesco Cresi,
  • Isadora Beghetti,
  • Paola Roggero,
  • Camilla Menis,
  • Luigi Corvaglia,
  • Fabio Mosca,
  • Arianna Aceti and
  • on behalf of the Study Group on Neonatal Nutrition and Gastroenterology—Italian Society of Neonatology

20 June 2020

Background: This systematic review summarizes available literature regarding complementary feeding (CF) in preterm infants, with or without comorbidities that may interfere with oral functions. Methods: A literature search was conducted in PubMed and...

  • Review
  • Open Access
2,117 Views
23 Pages

Histatin peptides are a family of small histidine-rich cationic polypeptides produced by two genes, HTN1 and HTN3. They are found in salivary secretions from the parotid, sublingual, and submandibular salivary glands. These peptides undergo proteolyt...

  • Article
  • Open Access
2 Citations
2,892 Views
10 Pages

Effect of Mucosal Brushing on the Serum Levels of C-Reactive Protein for Patients Hospitalized with Acute Symptoms

  • Naoko Nakahodo,
  • Yoshiaki Nomura,
  • Takumi Oshiro,
  • Ryoko Otsuka,
  • Erika Kakuta,
  • Ayako Okada,
  • Yuko Inai,
  • Noriko Takei and
  • Nobuhiro Hanada

19 October 2020

This study was based in a hospital setting. Patients with acute symptoms face a life-threatening crisis and often have systemic complications during the convalescence stage. During the acute stage, oral function does not work and oral hygiene status...

  • Article
  • Open Access
3 Citations
3,263 Views
13 Pages

Human Papilloma Virus (HPV) Detection in Oral Rinse vs. Oral Sponge: A Preliminary Accuracy Report in Oral Cancer Patients

  • Vera Panzarella,
  • Michela Buttà,
  • Fortunato Buttacavoli,
  • Giuseppina Capra,
  • Alberto Firenze,
  • Nicola Serra,
  • Giovanna Giuliana,
  • Giuseppe Pizzo,
  • Giuseppina Campisi and
  • Rodolfo Mauceri

24 September 2024

Background/Objectives: Human Papillomavirus (HPV) is a significant etiological factor in the development of oropharyngeal carcinogenesis. The detection of HPV in oral squamous cell carcinoma (OSCC) could be also crucial for diagnosis, prognosis, and...

  • Viewpoint
  • Open Access
11 Citations
3,722 Views
9 Pages

Use and Prescription of Direct Oral Anticoagulants in Older and Frail Patients with Atrial Fibrillation: A Multidisciplinary Consensus Document

  • Marco Proietti,
  • Marina Camera,
  • Maurizio Gallieni,
  • Luigi Gianturco,
  • Antonio Gidaro,
  • Carlo Piemontese,
  • Giuseppe Pizzetti,
  • Franco Redaelli,
  • Barbara Scimeca and
  • Carlo Sebastiano Tadeo
  • + 3 authors

15 March 2022

In the last twelve years the clinical management of patients with atrial fibrillation has been revolutionised by the introduction of direct oral anticoagulants. Despite the large amount of evidence produced, some populations remain relatively poorly...

  • Review
  • Open Access
5 Citations
4,374 Views
10 Pages

12 October 2023

Schizophrenia is a psychiatric disorder that makes patients incompetent to perform day-to-day activities due to their progressing mental illness. In addition to disturbances with thoughts, behavioral changes, and impaired cognitive functions, oro-sys...

  • Case Report
  • Open Access
8 Citations
5,260 Views
15 Pages

Oral Candida Infection in Psoriatic Patients Treated with IL17A Inhibitors: Report of 3 Cases and a Comprehensive Review of the Literature

  • Efstathios Pettas,
  • Vasiliki Savva,
  • Vasileios Ionas Theofilou,
  • Maria Georgaki and
  • Nikolaos G. Nikitakis

An intact and fully functional immune system plays a crucial role in the prevention of several infectious diseases. Interleukin (IL)17 is significantly involved in oral mucosa immunity against several antigens and microorganisms, including Candida al...

  • Feature Paper
  • Review
  • Open Access
18 Citations
5,643 Views
6 Pages

10 November 2017

Essential tremor is characterized by persistent, usually bilateral and symmetric, postural or kinetic activation of agonist and antagonist muscles involving either the distal or proximal upper extremity. Quality of life is often affected and one’s ab...

  • Review
  • Open Access
8 Citations
3,981 Views
17 Pages

Oral Microbiota in Children with Cleft Lip and Palate: A Systematic Review

  • Jacek Świtała,
  • Magdalena Sycińska-Dziarnowska,
  • Gianrico Spagnuolo,
  • Krzysztof Woźniak,
  • Katarzyna Mańkowska and
  • Liliana Szyszka-Sommerfeld

9 September 2023

Background: Cleft in the lip and/or palate (CLP) is a congenital facial deformity that significantly impacts the oral cavity’s structure and function. This malformation can affect the oral microbiota. The objective of this systematic review was...

  • Article
  • Open Access
2 Citations
3,037 Views
15 Pages

Specialized Management of Oral Anticoagulation Therapy Improves Outcome in Patients with Chronic Renal Insufficiency

  • Michael Lauterbach,
  • Eduard Uhrich,
  • Lisa Eggebrecht,
  • Sebastian Göbel,
  • Marina Panova-Noeva,
  • Markus Nagler,
  • Vincent ten Cate,
  • Christoph Bickel,
  • Christine Espinola-Klein and
  • Thomas Münzel
  • + 2 authors

28 February 2020

Oral anticoagulation (OAC) is effective at preventing and treating thromboses and thromboembolism in patients with normal renal function. We aimed to research the impact of severe renal failure (RF) on patient outcome and to determine the potential b...

  • Review
  • Open Access
4 Citations
112 Views
9 Pages

Antiplatelet Therapy Before Cardiac Surgery

  • Stefanos Demertzis,
  • Tiziano Cassina and
  • Gabriele Casso

Patients under double antiplatelet therapy (DAPT) waiting for cardiac surgery need careful multidisci plinary evaluation by the heart team. The decisions on if and when to stop oral DAPT and if, how and for how long to proceed to a bridge therapy, ha...

  • Article
  • Open Access
2 Citations
2,087 Views
11 Pages

Functional Disability and Symptomatic Slow-Acting Drugs for Osteoarthritis in Adults with Periodontitis

  • Nik-Madihah Nik-Azis,
  • Nurulhuda Mohd,
  • Badiah Baharin,
  • Fazalina Mohd Fadzilah,
  • Nor Hazla Mohamed Haflah and
  • Mohd Shahrir Mohamed Said

Osteoarthritis (OA) patients have decreased functional ability and restricted access to healthcare facilities and are on a spectrum of medications. These can impact their oral health. This study aims to investigate the association between periodontal...

  • Review
  • Open Access
15 Citations
16,411 Views
23 Pages

The Role of Ghrelin, Salivary Secretions, and Dental Care in Eating Disorders

  • Takakazu Yagi,
  • Hirotaka Ueda,
  • Haruka Amitani,
  • Akihiro Asakawa,
  • Shouichi Miyawaki and
  • Akio Inui

13 August 2012

Eating disorders, including anorexia and bulimia nervosa, are potentially life-threatening syndromes characterized by severe disturbances in eating behavior. An effective treatment strategy for these conditions remains to be established, as patients...

  • Article
  • Open Access
14 Citations
4,872 Views
13 Pages

dsRNA-Mediated Pest Management of Tuta absoluta Is Compatible with Its Biological Control Agent Nesidiocoris tenuis

  • Nomi Sarmah,
  • Athanasios Kaldis,
  • Clauvis Nji Tizi Taning,
  • Dionysios Perdikis,
  • Guy Smagghe and
  • Andreas Voloudakis

24 March 2021

RNAi-mediated insect pest management has recently shown promising results against the most serious pest of tomato, the tomato leafminer, Tuta absoluta. This study aimed to investigate whether dsRNA (dsTa-αCOP) designed to target the T. absoluta-αCOP...

  • Article
  • Open Access
3 Citations
3,166 Views
9 Pages

Efficacy and Safety in a Real-World Study of the New Oral Formulation of Semaglutide in Patients with Chronic Kidney Disease and Type 2 Diabetes Mellitus

  • María Marques Vidas,
  • Paula López-Sánchez,
  • Paula Sánchez-Briales,
  • María Victoria López Illazquez and
  • Jose Portolés

30 August 2024

Background/Objectives: GLP-1 receptor agonists (GLP-1RAs) have emerged as fundamental components in the treatment of type 2 diabetic patients (T2DM) with chronic kidney disease (CKD). The oral formulation represents a novel therapeutic tool but may a...

  • Review
  • Open Access
1 Citations
792 Views
17 Pages

Alzheimer’s Disease and Oral Health from Clinical Challenges to Interdisciplinary Care: A Narrative Review

  • Diana Tatarciuc,
  • Florin Razvan Curca,
  • Dragos Ioan Virvescu,
  • Oana Maria Butnaru,
  • Ancuta Goriuc,
  • Simona Bida,
  • Ionut Luchian,
  • Zinovia Surlari,
  • Mihaela Scurtu and
  • Ramona Gabriela Ursu
  • + 1 author

23 September 2025

The link between oral health and Alzheimer’s disease (AD) has gained increasing attention in recent years. Emerging evidence suggests that this association is bidirectional, involving both biological mechanisms and behavioral consequences that...

  • Review
  • Open Access
664 Views
11 Pages

Extraneural Soft Tissue Perineurioma of the Oral Cavity: A Rare Case with Medico-Legal Implications and Literature Review

  • Daniele Pergolini,
  • Mohamed Mohsen,
  • Simona Zaami,
  • Lina De Paola,
  • Federica Rocchetti,
  • Cinzia Angileri,
  • Eduardo Troiani,
  • Cira Rosaria Tiziana Di Gioia,
  • Giulia Coppola and
  • Gaspare Palaia

25 August 2025

Perineuriomas are a rare form of peripheral nerve sheath tumors, with occurrences in the oral cavity being exceptionally uncommon. This scarcity underscores the clinical significance of each documented case, as it facilitates enhanced diagnostic prec...

  • Article
  • Open Access
1 Citations
2,108 Views
24 Pages

30 September 2023

Being employed in a managerial position is often associated with maintaining high standards in many aspects of life. Many leaders pay attention to their physical activity, eating habits, and social skills. The onset of the COVID-19 pandemic brought a...

  • Perspective
  • Open Access
1,017 Views
12 Pages

Association Between Periodontitis and Cancer: A Perspective Review of Mechanisms and Clinical Evidence

  • Marco Bonilla,
  • Irene Peñalver,
  • María José Mesa-López and
  • Francisco Mesa

8 September 2025

Chronic periodontitis has emerged as a potential modifiable risk factor for several tumors, yet its role remains underexplored beyond epidemiological associations. This perspective review examines the immunological and molecular interplay between per...

of 9