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811 Results Found

  • Article
  • Open Access
7 Citations
3,077 Views
12 Pages

Obstetric Complications and Polygenic Risk Score: Which Role in Predicting a Severe Short-Term Outcome in Psychosis?

  • Sarah Tosato,
  • Chiara Bonetto,
  • Evangelos Vassos,
  • Antonio Lasalvia,
  • Katia De Santi,
  • Margherita Gelmetti,
  • Doriana Cristofalo,
  • Alexander Richards,
  • Mirella Ruggeri and
  • on behalf of the PICOS-Veneto Group

26 November 2021

Understanding and improving the outcomes of psychosis remains a major challenge for clinical research. Obstetric complications (OCs) as a risk factor for schizophrenia (SZ) have been investigated as a potential predictor of outcomes in relation to il...

  • Article
  • Open Access
7 Citations
3,099 Views
10 Pages

Early Prediction of Adverse Pregnancy Outcome in Women with Systemic Lupus Erythematosus, Antiphospholipid Syndrome, or Non-Criteria Obstetric Antiphospholipid Syndrome

  • Núria Baños,
  • Aleida Susana Castellanos,
  • Giuseppe Barilaro,
  • Francesc Figueras,
  • Gema María Lledó,
  • Marta Santana and
  • Gerard Espinosa

18 November 2022

A prospectively study of pregnant women with systemic lupus erythematosus (SLE), antiphospholipid syndrome, or non-criteria obstetric antiphospholipid syndrome was conducted to describe the characteristics of women followed in a referral unit and to...

  • Article
  • Open Access
30 Citations
4,153 Views
8 Pages

Obstetric and Neonatal Outcomes following COVID-19 Vaccination in Pregnancy

  • Ravit Peretz-Machluf,
  • Galit Hirsh-Yechezkel,
  • Inna Zaslavsky-Paltiel,
  • Adel Farhi,
  • Nir Avisar,
  • Liat Lerner-Geva,
  • Raanan Meyer,
  • Abraham Tsur and
  • Yoav Yinon

30 April 2022

COVID-19 infection imposes a risk for pregnant individuals and may lead to adverse maternal and obstetric outcomes. This is a retrospective cohort study of all women giving birth between March and July 2021 at a single tertiary center. Obstetric and...

  • Article
  • Open Access
6 Citations
3,254 Views
6 Pages

Obstetric Outcomes after Perforation of Uterine Cavity

  • Polina Schwarzman,
  • Yael Baumfeld,
  • Salvatore Andrea Mastrolia,
  • Shimrit Yaniv-Salem,
  • Elad Leron and
  • Tali Silberstein

30 July 2022

We aimed to evaluate the pregnancy characteristics and obstetric outcomes in patients after perforation of the uterus. Study design: A retrospective cohort study was conducted and included all patients who were diagnosed with uterine perforation and...

  • Article
  • Open Access
2,584 Views
13 Pages

Obstetrical and Perinatal Outcomes Are Not Associated with Advanced Paternal Age in IVF or ICSI Pregnancies with Autologous Oocytes

  • Ana Navarro-Gomezlechon,
  • María Gil Juliá,
  • Rosa María Pacheco-Rendón,
  • Irene Hervás,
  • Laura Mossetti,
  • Rocío Rivera-Egea and
  • Nicolás Garrido

20 September 2023

Background: In recent years, there has been an evident delay in childbearing and concerns have been raised about whether this increase in age affects reproductive outcomes. This study aimed to evaluate the effect of paternal age on obstetrical and pe...

  • Article
  • Open Access
3,329 Views
15 Pages

Pregnancy Outcomes in Non-Criteria Obstetric Antiphospholipid Syndrome: Analysis of a Cohort of 91 Patients

  • Sara Beça,
  • Núria Baños,
  • Maria Borrell,
  • Estíbaliz Ruiz-Ortiz,
  • Albert Pérez-Isidro,
  • Ricard Cervera,
  • Joan Carles Reverter,
  • Dolores Tàssies and
  • Gerard Espinosa

23 December 2024

Background: The clinical and laboratory features of patients with non-criteria obstetric antiphospholipid syndrome (NC-OAPS), as well as their pregnancy outcomes and ideal treatment are not clearly determined. The aim of this study is to describe the...

  • Article
  • Open Access
3 Citations
3,067 Views
11 Pages

Association between Abnormal Echocardiography and Adverse Obstetric Outcomes in Low-Risk Pregnant Women

  • Kerrilynn C. Hennessey,
  • Thara S. Ali,
  • Eunjung Choi,
  • Alexandra R. Ortengren,
  • Leigh C. Hickerson,
  • Jennifer May Lee and
  • Cynthia C. Taub

Maternal mortality in the United States is a public health crisis of preventable deaths among young women. The role of echocardiography in the evaluation of pregnant women with cardiovascular symptoms or risk factors without known heart disease is un...

  • Article
  • Open Access
28 Citations
11,556 Views
23 Pages

20 October 2021

Congenital uterine anomalies (CUA) may influence reproductive performance, resulting in adverse pregnancy associated complications. This study aimed to assess the association of CUA subtypes with reproductive, obstetric, and perinatal outcomes. We pe...

  • Article
  • Open Access
1,336 Views
16 Pages

A Decade of Experience in Diagnostic and Conservative Treatment of Endometrial Malignancy—Oncologic and Obstetrical Outcomes from a Referral Oncofertility Center

  • Katarina Stefanovic,
  • Jelena Dotlic,
  • Igor Pilic,
  • Branislav Milosevic,
  • Olga Mihaljevic,
  • Aleksandra Beleslin and
  • Aleksandar Stefanović

Background/Objectives: This study aimed to investigate oncologic and obstetrical outcomes of patients conservatively treated for atypical hyperplasia (AH), endometrial intraepithelial neoplasm (EIN), and early endometrial cancer (EC), as well as fact...

  • Brief Report
  • Open Access
13 Citations
3,922 Views
8 Pages

In Underweight Women, Insufficient Gestational Weight Gain Is Associated with Adverse Obstetric Outcomes

  • Alizée Montvignier Monnet,
  • Delphine Savoy,
  • Lise Préaubert,
  • Pascale Hoffmann and
  • Cécile Bétry

23 December 2022

The pre-pregnancy BMI and the gestational weight gain are two important determinants of pregnancy outcomes. The aim of this study was to determine obstetric outcomes associated with insufficient gestational weight gain in women with a pre-pregnancy B...

  • Systematic Review
  • Open Access
589 Views
17 Pages

Obstetric Complications and Pregnancy Outcomes in Cancer Survivors: A Systematic Review and Meta-Analysis

  • Charmaine Yong Ching Lee,
  • Isaac Yongjie Sim,
  • Chen Ee Low,
  • Tessa Ying Zhen Tan,
  • Abdul Fattah Lee Abdul Aziz,
  • Zhongwei Huang,
  • Jeremy Chee Seong Tey and
  • Ainsley Ryan Yan Bin Lee

8 December 2025

Background: With advances in cancer diagnosis and therapy, survival after childhood and young-adult cancers has improved markedly. As survivorship extends, understanding long-term health sequelae, including obstetric outcomes, has become increasingly...

  • Article
  • Open Access
19 Citations
4,491 Views
14 Pages

Associations between Prenatal Physical Activity and Neonatal and Obstetric Outcomes—A Secondary Analysis of the Cluster-Randomized GeliS Trial

  • Julia Hoffmann,
  • Julia Günther,
  • Kristina Geyer,
  • Lynne Stecher,
  • Julia Kunath,
  • Dorothy Meyer,
  • Monika Spies,
  • Eva Rosenfeld,
  • Luzia Kick and
  • Hans Hauner
  • + 1 author

19 October 2019

Prenatal physical activity (PA) was discussed to decrease the incidence of obstetric and neonatal complications. In this secondary cohort analysis of the cluster-randomized GeliS (“healthy living in pregnancy”) trial, associations between...

  • Article
  • Open Access
3 Citations
3,073 Views
12 Pages

Eight-Year Trends in the Effect of the Great East Japan Earthquake on Obstetrics Outcomes: A Study from the Fukushima Health Management Survey

  • Hyo Kyozuka,
  • Tetsuya Ohhira,
  • Tsuyoshi Murata,
  • Shun Yasuda,
  • Kayoko Ishii,
  • Seiji Yasumura,
  • Keiya Fujimori,
  • Hitoshi Ohto and
  • Kenji Kamiya

8 August 2023

Information regarding the longitudinal effects of natural/environmental disasters on obstetrics outcomes is limited. This study aimed to analyze the longitudinal changes in obstetrics outcomes over 8 years after the Great East Japan Earthquake and th...

  • Article
  • Open Access
10 Citations
3,836 Views
17 Pages

Time to Pregnancy, Obstetrical and Neonatal Outcomes after Breast Cancer: A Study from the Maternity Network for Young Breast Cancer Patients

  • Julie Labrosse,
  • Anne Lecourt,
  • Alice Hours,
  • Clara Sebbag,
  • Aullene Toussaint,
  • Enora Laas,
  • Florence Coussy,
  • Beatriz Grandal,
  • Elise Dumas and
  • Anne-Sophie Hamy
  • + 6 authors

3 March 2021

Although an increasing number of young breast cancer (BC) patients have a pregnancy desire after BC, the time necessary to obtain a pregnancy after treatment and subsequent outcomes remain unknown. We aimed to determine the time to evolutive pregnanc...

  • Article
  • Open Access
1 Citations
2,416 Views
13 Pages

The prevalence of chronic diseases during pregnancy and adverse maternal obstetric outcomes in Switzerland has been insufficiently studied. Data sources, which reliably capture these events, are scarce. We conducted a nationwide observational cross-s...

  • Article
  • Open Access
1 Citations
4,269 Views
13 Pages

Endocrine Characteristics and Obstetric Outcomes of PCOS Patients with Successful IVF and Non-IVF Pregnancies

  • Mónika Orosz,
  • Fanni Borics,
  • Dávid Rátonyi,
  • Zoárd Tibor Krasznai,
  • Beáta Vida,
  • Tünde Herman,
  • Szilvia Csehely,
  • Attila Jakab,
  • Luca Lukács and
  • Tamás Deli
  • + 1 author

21 September 2024

Background/Objective: Infertility affects an estimated 40–50% of women with polycystic ovary syndrome (PCOS), the leading cause of anovulatory infertility, but only a small proportion of the patients require in vitro fertilization (IVF) therapy...

  • Article
  • Open Access
2 Citations
2,860 Views
11 Pages

Advanced Paternal Age Does Not Affect Medically-Relevant Obstetrical and Perinatal Outcomes following IVF or ICSI in Humans with Donated Oocytes

  • Ana Navarro-Gomezlechon,
  • María Gil Juliá,
  • Irene Hervás,
  • Laura Mossetti,
  • Rocío Rivera-Egea and
  • Nicolás Garrido

28 January 2023

Background: Concomitant with delays in childbearing, concerns have been raised of whether advanced paternal age is associated with adverse reproductive outcomes, but the evidence is controversial in part due to the uncertain threshold in which to con...

  • Review
  • Open Access
14 Citations
7,808 Views
21 Pages

Reproductive and Obstetric Outcomes after Fertility-Sparing Treatments for Cervical Cancer: Current Approach and Future Directions

  • Milan Terzic,
  • Dinara Makhadiyeva,
  • Jovan Bila,
  • Mladen Andjic,
  • Jelena Dotlic,
  • Gulzhanat Aimagambetova,
  • Antonio Sarria-Santamera,
  • Antonio Simone Laganà,
  • Vito Chiantera and
  • Sanja Terzic
  • + 4 authors

30 March 2023

Cervical cancer is one of the leading causes of cancer-related death in women of reproductive age. The established fertility-sparing approaches for the management of early-stage cervical cancer for women who plan pregnancy are associated with a decli...

  • Article
  • Open Access
1 Citations
2,113 Views
15 Pages

Pre-Conception Androgen Levels and Obstetric Outcomes in Polycystic Ovary Syndrome: A Single-Center Retrospective Study

  • Mónika Orosz,
  • Fanni Borics,
  • Dávid Rátonyi,
  • Beáta Vida,
  • Szilvia Csehely,
  • Attila Jakab,
  • Luca Lukács,
  • Rudolf Lampé and
  • Tamás Deli

8 October 2024

Hyperandrogenism is a determining diagnostic factor for PCOS. If pregnancy is conceived, it is considered high-risk due to several potential complications, but the correlation between pre-pregnancy androgen levels and obstetric outcomes is poorly cha...

  • Review
  • Open Access
4,904 Views
19 Pages

Impact of Maternal Smoking on Obstetric and Neonatal Outcomes in Twin Pregnancies: A Narrative Review

  • Cristina Juliá-Burchés,
  • Alicia Martínez-Varea,
  • José Morales-Roselló and
  • Vicente Diago-Almela

2 December 2024

Maternal smoking, including both traditional cigarettes and electronic ones, is a significant modifiable risk factor associated with adverse perinatal outcomes, especially in twin pregnancies. This narrative review aims to explore the impact of mater...

  • Article
  • Open Access
9 Citations
8,006 Views
8 Pages

The Relationship between Nuchal Cord and Adverse Obstetric and Neonatal Outcomes: Retrospective Cohort Study

  • Marta Młodawska,
  • Jakub Młodawski,
  • Grzegorz Świercz and
  • Rafał Zieliński

24 January 2022

Objective: The twisting of the umbilical cord around the fetal neck is a common phenomenon in the delivery room, and despite the lack of univocal evidence of its negative impact on perinatal events, it causes anxiety and stress in patients. The aim o...

  • Review
  • Open Access
44 Citations
10,765 Views
29 Pages

Climate change is accelerating the intensity and frequency of wildfires globally. Understanding how wildfire smoke (WS) may lead to adverse pregnancy outcomes and alterations in placental function via biological mechanisms is critical to mitigate the...

  • Article
  • Open Access
10 Citations
4,544 Views
11 Pages

Reproductive and Obstetric Outcomes Following a Natural Cycle vs. Artificial Endometrial Preparation for Frozen–Thawed Embryo Transfer: A Retrospective Cohort Study

  • Andrea Roberto Carosso,
  • Nicole Brunod,
  • Claudia Filippini,
  • Alberto Revelli,
  • Bernadette Evangelisti,
  • Stefano Cosma,
  • Fulvio Borella,
  • Stefano Canosa,
  • Chiara Benedetto and
  • Gianluca Gennarelli

13 June 2023

Background: The proportion of frozen embryo transfer cycles has consistently grown in recent decades. Some adverse obstetric outcomes after frozen embryo transfer could possibly be explained by different approaches in endometrial preparation. The aim...

  • Article
  • Open Access
5 Citations
1,762 Views
9 Pages

Adverse Obstetric Outcomes after Breast Cancer Diagnosis: An Observational Database Study in Germany

  • Anna Sophie Scholz,
  • Alexandra von Au,
  • Raphael Gutsfeld,
  • Tjeerd Maarten Hein Dijkstra,
  • Dominik Dannehl,
  • Kathrin Hassdenteufel,
  • Markus Hahn,
  • Sabine Hawighorst-Knapstein,
  • Ariane Chaudhuri and
  • Stephanie Wallwiener
  • + 4 authors

22 September 2024

Background/Objectives: Breast cancer may negatively affect later pregnancy and childbirth. We aimed to analyze the impact of previous breast cancer on obstetric outcomes in postdiagnosis pregnancies. Methods: Insurance claims data in Southern Germany...

  • Article
  • Open Access
754 Views
12 Pages

Perinatal Outcomes in Mexican Women with a History of Myomectomy: A Retrospective Cohort Study

  • Fela Vanesa Morales-Hernández,
  • Jocelyn Andrea Almada-Balderrama,
  • Andrea Alicia Olguín-Ortega,
  • Pilar de Abiega-Franyutti,
  • Enrique Reyes-Muñoz and
  • Myrna Souraye Godines-Enriquez

29 October 2025

Background/Objectives: Myomectomy is the preferred treatment for women with uterine fibroids who desire to preserve their fertility. This study aimed to compare perinatal outcomes between Mexican women with and without a history of myomectomy, matche...

  • Review
  • Open Access
13 Citations
5,064 Views
11 Pages

SARS-CoV-2 Footprints in the Placenta: What We Know after Three Years of the Pandemic

  • Valentina Tosto,
  • Arun Meyyazhagan,
  • Malek Alqasem,
  • Valentina Tsibizova and
  • Gian Carlo Di Renzo

21 April 2023

As the COVID-19 pandemic continues into its third year, there is accumulating evidence on the consequences of maternal infection. Emerging data indicate increased obstetrics risks, including maternal complications, preterm births, impaired intrauteri...

  • Article
  • Open Access
1 Citations
1,899 Views
8 Pages

Gestational Hydronephrosis: A Retrospective Analysis of the Clinical Outcomes of Ureteral Stent Placement Versus Conservative Treatment

  • Dursun Baba,
  • Engin Yurtçu,
  • Burak Ayvacık,
  • Yusuf Salih Küçük,
  • Arda Taşkın Taşkıran,
  • Mehmet Ali Özel,
  • Ahmet Yıldırım Balık,
  • Ekrem Başaran and
  • Betül Keyif

Background and Objectives: Gestational hydronephrosis (GH) is a physiological condition commonly observed during pregnancy, resulting from hormonal effects and mechanical compression of the ureters by the enlarging uterus. Although often asymptomatic...

  • Communication
  • Open Access
3 Citations
2,855 Views
10 Pages

TCF7L2 Polymorphism rs7903146 (C/T) and Gestational Diabetes Influence on Obstetric Outcome: A Romanian Case–Control Study

  • Gheorghe Cruciat,
  • Andreea Roxana Florian,
  • Mariam-Suzana Chaikh-Sulaiman,
  • Adelina Staicu,
  • Gabriela Valentina Caracostea,
  • Lucia Maria Procopciuc,
  • Florin Stamatian and
  • Daniel Muresan

Gestational diabetes mellitus (GDM) is one of the most frequent predictors of obstetric outcome among Romanian pregnant women. Thus, we aimed to investigate the role of rs7903146 (C/T) TCF7L2 gene polymorphism in the presence of GDM and to evaluate t...

  • Review
  • Open Access
15 Citations
3,877 Views
13 Pages

Pregnancy and COVID-19

  • Thomas Ntounis,
  • Ioannis Prokopakis,
  • Antonios Koutras,
  • Zacharias Fasoulakis,
  • Savia Pittokopitou,
  • Asimina Valsamaki,
  • Athanasios Chionis,
  • Evangelia Kontogeorgi,
  • Vasiliki Lampraki and
  • Emmanuel N. Kontomanolis
  • + 11 authors

9 November 2022

Evidence indicates that SARS-CoV-2 infection increases the likelihood of adverse pregnancy outcomes. Modifications in the circulatory, pulmonary, hormonal, and immunological pathways induced by pregnancy render pregnant women as a high-risk group. A...

  • Article
  • Open Access
12 Citations
3,200 Views
10 Pages

Fertility-Sparing Treatment for Endometrial Cancer: Oncological and Obstetric Outcomes in Combined Therapies with Levonorgestrel Intrauterine Device

  • Ida Pino,
  • Anna Daniela Iacobone,
  • Ailyn Mariela Vidal Urbinati,
  • Maria Di Giminiani,
  • Davide Radice,
  • Maria Elena Guerrieri,
  • Eleonora Petra Preti,
  • Silvia Martella and
  • Dorella Franchi

26 April 2022

Background: The prevalence of reaches up to 5% in women younger than 40 years. Therefore, the fertility preservation should be the goal of the clinical practice in women with desire of pregnancy and low-risk features. The aim of this study is to comp...

  • Article
  • Open Access
3 Citations
6,293 Views
10 Pages

24 January 2024

Background: We investigated the association between placental location and pregnancy outcomes in placenta previa. Methods: This multi-center retrospective study enrolled 781 women who delivered between May 1999 and February 2020. We divided the datas...

  • Article
  • Open Access
6 Citations
4,000 Views
17 Pages

Marfan Syndrome Versus Bicuspid Aortic Valve Disease: Comparative Analysis of Obstetric Outcome and Pregnancy-Associated Immediate and Long-Term Aortic Complications

  • Betül Toprak,
  • Katalin Szöcs,
  • Elvin Zengin-Sahm,
  • Christoph Sinning,
  • Amra Hot,
  • Peter Bannas,
  • Kurt Hecher,
  • Bernd Hüneke,
  • Thomas S. Mir and
  • Yskert von Kodolitsch
  • + 3 authors

15 April 2020

Pregnancy poses a threat to women with aortopathy. Conclusive data on the obstetric and aortic outcome in this risk collective, especially when it comes to aortic complications in the long term, are still missing. This study offers a comparative anal...

  • Article
  • Open Access
17 Citations
2,698 Views
8 Pages

Clinical Manifestation and Obstetric Outcomes in Pregnant Women with SARS-CoV-2 Infection at Delivery: A Retrospective Cohort Analysis

  • Gordana Grgić,
  • Anis Cerovac,
  • Igor Hudić,
  • Antonio Simone Laganà,
  • Alessandro Favilli,
  • Simone Garzon,
  • Vito Chiantera,
  • Chrysoula Margioula-Siarkou,
  • Azra Hadžimehmedović and
  • Amer Mandžić

9 September 2022

This retrospective cohort study aimed to analyze the clinical manifestations, complications, and maternal-fetal outcomes in patients affected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during delivery. The cohort includ...

  • Article
  • Open Access
5 Citations
4,519 Views
12 Pages

Maternal Obesity in Twin Pregnancy: The Role of Nutrition to Reduce Maternal and Fetal Complications

  • María de la Calle,
  • Jose L. Bartha,
  • Clara Marín,
  • Juan Carlos Rus,
  • Guillermo Córcoles,
  • Santiago Ruvira and
  • David Ramiro-Cortijo

22 March 2022

There are more and more obese mothers with twin gestations. For a long time before, the responses of lymphocytes and platelets in obese women can cause a low-grade inflammation. In addition, a proper control of gestational weight gain would improve t...

  • Article
  • Open Access
20 Citations
15,198 Views
14 Pages

Uterine Fibroids and Pregnancy: A Review of the Challenges from a Romanian Tertiary Level Institution

  • Mihaela Camelia Tîrnovanu,
  • Ludmila Lozneanu,
  • Ştefan Dragoş Tîrnovanu,
  • Vlad Gabriel Tîrnovanu,
  • Mircea Onofriescu,
  • Carmen Ungureanu,
  • Bogdan Florin Toma and
  • Elena Cojocaru

Background and Objectives. Uterine fibroids are relatively common in reproductive-age women and are directly linked to pregnancy. There are many debates about performing a myomectomy at the same time as a caesarian section (CS) in such cases due to t...

  • Review
  • Open Access
7 Citations
5,342 Views
19 Pages

8 October 2023

Chronic diseases are potential risk factors for pregnancy duration and neonatal outcomes. This narrative review aimed to summarize the research results on the specifics of pregnancy in women with obesity and after bariatric surgery. PubMed and Google...

  • Article
  • Open Access
7 Citations
2,558 Views
11 Pages

Obesity during Pregnancy and SARS-CoV-2/COVID-19-Case Series of the Registry Study “COVID-19 Related Obstetric and Neonatal Outcome Study” (CRONOS-Network)

  • Friederike Weschenfelder,
  • Janine Zöllkau,
  • Anna Schohe,
  • Ulrich Pecks,
  • Tanja Groten,
  • Ute Schaefer-Graf and
  • on behalf of CRONOS-Network

7 March 2023

(1) Background: Obesity is an increasing challenge in the care of pregnant women. The aim of our study was to investigate whether obesity is an independent risk factor for severe maternal and neonatal outcomes in pregnant women with COVID-19. (2) Met...

  • Systematic Review
  • Open Access
4 Citations
3,371 Views
15 Pages

Preterm Birth and SARS-CoV-2: Does a Correlation Exist?

  • Federica Perelli,
  • Annalisa Vidiri,
  • Giovanna Palomba,
  • Rita Franco,
  • Vitalba Gallitelli,
  • Marco Parasiliti,
  • Marta Bisanti,
  • Amelia Spanò,
  • Adele Silvagni and
  • Anna Franca Cavaliere
  • + 3 authors

Introduction: The emergence of the SARS-CoV-2 virus and its subsequent global pandemic have raised significant concerns regarding its impact on pregnancy outcomes. This review aims to summarize the emerging data on the risk of preterm delivery in pre...

  • Article
  • Open Access
2 Citations
2,745 Views
10 Pages

Outcomes after In Utero Myelomeningocele Repair Based on Delivery Location

  • Eric P. Bergh,
  • Kuojen Tsao,
  • Mary T. Austin,
  • Stephen A. Fletcher,
  • Suzanne M. Lopez,
  • Kenneth J. Moise,
  • Anthony Johnson and
  • Ramesha Papanna

27 October 2020

Maternal and pediatric delivery outcomes may vary in patients who underwent open fetal myelomeningocele repair and elected to deliver at the fetal center where their fetal intervention was performed versus at the referring physician’s hospital....

  • Article
  • Open Access
5 Citations
9,812 Views
17 Pages

Despite extensive knowledge of the mechanisms responsible for childbirth, the course of labor induction is often unpredictable. Therefore, labor induction protocols using prostaglandin analogs have been developed and tested to assess their effectiven...

  • Article
  • Open Access
1,637 Views
15 Pages

The Development of a Forceps-Adaptable Pressure Device for Instrumental Delivery: A Proof-of-Concept Study for Clinical and Educational Applications

  • Mathieu Hivert,
  • Cyril Bengler,
  • Julien De Jonckheere,
  • Franck Gaultier,
  • Marie Pécout,
  • Olivier Mayeur and
  • Chrystèle Rubod

8 December 2024

Objective: To develop and validate a device that measures the pressure exerted by forceps on the fetal head for clinical use. Background: The lack of clinical tools to quantify forceps pressure on the fetal head may impact maternal and neonatal outco...

  • Review
  • Open Access
2 Citations
3,391 Views
13 Pages

Anesthetic Management for Delivery in Parturients with Heart Disease: A Narrative Review

  • Shahab Ahmadzadeh,
  • Drake P. Duplechin,
  • Paris D. Bailey,
  • Dillon T. Duplechan,
  • Alexia J. Enache,
  • Peyton Moore and
  • Sahar Shekoohi

Cardiac disease remains a leading cause of maternal morbidity and mortality, particularly in developed countries where improved survival has increased the number of pregnant patients with congenital heart disease. The physiological changes of pregnan...

  • Article
  • Open Access
10 Citations
10,105 Views
13 Pages

Umbilical Cord Diseases Affecting Obstetric and Perinatal Outcomes

  • Gabriele Tonni,
  • Mario Lituania,
  • Alessandro Cecchi,
  • Elisa Carboni,
  • Serena Resta,
  • Maria Paola Bonasoni and
  • Rodrigo Ruano

27 September 2023

Background: (1) The aim of this article is to describe the physiopathology underlying umbilical cord diseases and their relationship with obstetric and perinatal outcomes. (2) Methods: Multicenter case series of umbilical cord diseases with illustrat...

  • Article
  • Open Access
1,216 Views
12 Pages

Maternal Vitamin D Deficiency and the Risk of Placental Abruption: A Cross-Sectional Study in a Greek Obstetric Population

  • Artemisia Kokkinari,
  • Evangelia Antoniou,
  • Eirini Orovou,
  • Maria Dagla,
  • Maria Tzitiridou-Chatzopoulou,
  • Antigoni Sarantaki,
  • Kleanthi Gourounti and
  • Georgios Iatrakis

Background: Vitamin D deficiency (VDD) during pregnancy has been associated with various obstetric complications, including preeclampsia, gestational diabetes, and premature rupture of membranes. However, its potential link to placental abruption rem...

  • Review
  • Open Access
50 Citations
9,934 Views
16 Pages

Environmental Contaminants Exposure and Preterm Birth: A Systematic Review

  • Maria Grazia Porpora,
  • Ilaria Piacenti,
  • Sara Scaramuzzino,
  • Luisa Masciullo,
  • Francesco Rech and
  • Pierluigi Benedetti Panici

1 March 2019

Preterm birth is an obstetric condition associated with a high risk of infant mortality and morbidities in both the neonatal period and later in life, which has also a significant public health impact because it carries an important societal economic...

  • Review
  • Open Access
22 Citations
8,573 Views
22 Pages

Mitochondrial Toxicity in Human Pregnancy: An Update on Clinical and Experimental Approaches in the Last 10 Years

  • Constanza Morén,
  • Sandra Hernández,
  • Mariona Guitart-Mampel and
  • Glòria Garrabou

Mitochondrial toxicity can be one of the most dreadful consequences of exposure to a wide range of external agents including pathogens, therapeutic agents, abuse drugs, toxic gases and other harmful chemical substances. However, little is known about...

  • Article
  • Open Access
12 Citations
4,959 Views
17 Pages

TIMER: A Clinical Study of Energy Restriction in Women with Gestational Diabetes Mellitus

  • Efrosini Tsirou,
  • Maria G. Grammatikopoulou,
  • Meletios P. Nigdelis,
  • Eleftheria Taousani,
  • Dimitra Savvaki,
  • Efstratios Assimakopoulos,
  • Apostolos Tsapas and
  • Dimitrios G. Goulis

18 July 2021

Medical nutrition therapy is an integral part of gestational diabetes mellitus (GDM) management; however, the prescription of optimal energy intake is often a difficult task due to the limited available evidence. The present pilot, feasibility, paral...

  • Review
  • Open Access
7 Citations
3,777 Views
12 Pages

Ceramides during Pregnancy and Obstetrical Adverse Outcomes

  • Maria Lantzanaki,
  • Theofanis Vavilis,
  • Vikentia C. Harizopoulou,
  • Helen Bili,
  • Dimitrios G. Goulis and
  • Dimitrios Vavilis

8 November 2023

Ceramides are a group of sphingolipids located in the external plasma membrane layer and act as messengers in cellular pathways such as inflammatory processes and apoptosis. Plasma ceramides are biomarkers of cardiovascular disease, type 2 diabetes m...

  • Article
  • Open Access
563 Views
25 Pages

Mathematical Modeling of Obstetric Variables: Influence of COVID-19, Periodontal Disease and Dental Care During Pregnancy

  • Juliana Velosa-Porras,
  • Sandra Catalina Correa Herrera,
  • Katherine Lucia Mejía Reyes,
  • Paula Sofía Fuentes Rojas,
  • Laura Daniela Ardila Ortiz,
  • Olga Lucía Ospina,
  • Signed Prieto-Bohórquez,
  • Jairo Javier Jattin Balcázar,
  • Jorge Edgar Guevara Muñoz and
  • Nelly S. Roa
  • + 4 authors

28 November 2025

Background: Systemic inflammatory factors may be altered by periodontitis and/or COVID-19, potentially increasing the risk of adverse pregnancy outcomes, a relationship that remains unclear. Objective: This study aimed to identify associations betwee...

  • Article
  • Open Access
1,141 Views
20 Pages

Empirical Antibiotic Therapy in Chronic Endometritis With and Without Focal Lesions: A Prospective Cohort Study

  • Iwona Gawron,
  • Lucja Zaborowska,
  • Kamil Derbisz,
  • Inga Ludwin and
  • Artur Ludwin

21 November 2025

Objective: This study aimed to evaluate the efficacy of empirical antibiotic therapy in treating chronic endometritis (CE) associated with abnormal uterine bleeding (AUB), infertility, or intrauterine lesions. Methods: The prospective cohort study in...

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