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Environmental Contaminants Exposure and Preterm Birth: A Systematic Review

Department of Maternal and Child Health and Urology, University of Rome “Sapienza”, Policlinico “Umberto I”, 00161 Rome, Italy
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Toxics 2019, 7(1), 11; https://doi.org/10.3390/toxics7010011
Received: 15 January 2019 / Revised: 4 February 2019 / Accepted: 25 February 2019 / Published: 1 March 2019
(This article belongs to the Special Issue Prenatal Exposure to Toxics and Risks in Infants)
Preterm birth is an obstetric condition associated with a high risk of infant mortality and morbidities in both the neonatal period and later in life, which has also a significant public health impact because it carries an important societal economic burden. As in many cases the etiology is unknown, it is important to identify environmental factors that may be involved in the occurrence of this condition. In this review, we report all the studies published in PubMed and Scopus databases from January 1992 to January 2019, accessible as full-text articles, written in English, including clinical studies, original studies, and reviews. We excluded articles not written in English, duplicates, considering inappropriate populations and/or exposures or irrelevant outcomes and patients with known risk factors for preterm birth (PTB). The aim of this article is to identify and summarize the studies that examine environmental toxicants exposure associated with preterm birth. This knowledge will strengthen the possibility to develop strategies to reduce the exposure to these toxicants and apply clinical measures for preterm birth prevention. View Full-Text
Keywords: air pollution; environmental toxicants; environmental exposure; particulate matter; drinking water contaminant; tobacco smoke; polycyclic aromatic hydrocarbons; pregnancy outcomes; preterm birth; obstetrical complications air pollution; environmental toxicants; environmental exposure; particulate matter; drinking water contaminant; tobacco smoke; polycyclic aromatic hydrocarbons; pregnancy outcomes; preterm birth; obstetrical complications
MDPI and ACS Style

Porpora, M.G.; Piacenti, I.; Scaramuzzino, S.; Masciullo, L.; Rech, F.; Benedetti Panici, P. Environmental Contaminants Exposure and Preterm Birth: A Systematic Review. Toxics 2019, 7, 11.

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