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730 Results Found

  • Article
  • Open Access
2 Citations
2,105 Views
11 Pages

11 August 2023

Digital microfluidic platforms have been extensively studied in biology. However, achieving efficient mixing of macromolecules in microscale, low Reynolds number fluids remains a major challenge. To address this challenge, this study presents a novel...

  • Article
  • Open Access
215 Citations
83,624 Views
10 Pages

Micro- and Nanoplastics Breach the Blood–Brain Barrier (BBB): Biomolecular Corona’s Role Revealed

  • Verena Kopatz,
  • Kevin Wen,
  • Tibor Kovács,
  • Alison S. Keimowitz,
  • Verena Pichler,
  • Joachim Widder,
  • A. Dick Vethaak,
  • Oldamur Hollóczki and
  • Lukas Kenner

19 April 2023

Humans are continuously exposed to polymeric materials such as in textiles, car tires and packaging. Unfortunately, their break down products pollute our environment, leading to widespread contamination with micro- and nanoplastics (MNPs). The blood&...

  • Article
  • Open Access
8 Citations
10,789 Views
10 Pages

Fabrication of SiNx Thin Film of Micro Dielectric Barrier Discharge Reactor for Maskless Nanoscale Etching

  • Qiang Li,
  • Jie Liu,
  • Yichuan Dai,
  • Wushu Xiang,
  • Man Zhang,
  • Hai Wang and
  • Li Wen

14 December 2016

The prevention of glow-to-arc transition exhibited by micro dielectric barrier discharge (MDBD), as well as its long lifetime, has generated much excitement across a variety of applications. Silicon nitride (SiNx) is often used as a dielectric barrie...

  • Article
  • Open Access
2 Citations
4,140 Views
29 Pages

Performance Characteristics of A Micro Wind Turbine Integrated on A Noise Barrier

  • Nikolaos Chrysochoidis-Antsos,
  • Gerard J.W. van Bussel,
  • Jan Bozelie,
  • Sander M. Mertens and
  • Ad J.M. van Wijk

26 February 2021

Micro wind turbines can be structurally integrated on top of the solid base of noise barriers near highways. A number of performance factors were assessed with holistic experiments in wind tunnel and in the field. The wind turbines underperformed whe...

  • Article
  • Open Access
21 Citations
7,048 Views
25 Pages

Sound Insulation and Reflection Properties of Sonic Crystal Barrier Based on Micro-Perforated Cylinders

  • Stefan M. Dimitrijević,
  • Víctor M. García-Chocano,
  • Francisco Cervera,
  • Emelie Roth and
  • José Sánchez-Dehesa

31 August 2019

A sonic crystal barrier, consisting of empty micro-perforated cylindrical shells, was built on the campus at the Universitat Politècnica de València in 2011 and characterised by using a non-standardised measurement technique. In this pa...

  • Review
  • Open Access
44 Citations
9,168 Views
25 Pages

Macro and Micro Routes to High Performance Bioplastics: Bioplastic Biodegradability and Mechanical and Barrier Properties

  • Olivia A. Attallah,
  • Marija Mojicevic,
  • Eduardo Lanzagorta Garcia,
  • Muhammad Azeem,
  • Yuanyuan Chen,
  • Shumayl Asmawi and
  • Margaret Brenan Fournet

30 June 2021

On a score sheet for plastics, bioplastics have a medium score for combined mechanical performance and a high score for biodegradability with respect to counterpart petroleum-based plastics. Analysis quickly confirms that endeavours to increase the m...

  • Article
  • Open Access
7 Citations
3,191 Views
16 Pages

Thermal Conductivity of Multi-Sized Porous Thermal Barrier Coatings at Micro and Nano Scales after Long-Term Service at High Temperatures

  • Pei-Hu Gao,
  • Sheng-Cong Zeng,
  • Can Jin,
  • Bo Zhang,
  • Bai-Yang Chen,
  • Zhong Yang,
  • Yong-Chun Guo,
  • Min-Xian Liang,
  • Jian-Ping Li and
  • Quan-Ping Li
  • + 3 authors

29 September 2021

Thermal barrier coatings with multi-sized porous structure at micro and nano scales were prepared with hollow spherical YSZ powders and polypropylene powders through atmospheric plasma spraying. The thermal conductivities of the multi-sized thermal b...

  • Article
  • Open Access
65 Citations
6,564 Views
12 Pages

Cerebral edema, primarily caused by disruption of the blood-brain barrier (BBB), is one of the serious complications associated with brain injury in neonatal hypoxic-ischemic encephalopathy (HIE). Our recent study demonstrated that the hypoxic-ischem...

  • Article
  • Open Access
346 Views
20 Pages

YOLOv11-LADC: A Lightweight Detection Framework for Micro–Nano Damage Precursors in Thermal Barrier Coatings

  • Cong Huang,
  • Xing Peng,
  • Feng Shi,
  • Ci Song,
  • Hongbing Cao,
  • Xinjie Zhao and
  • Hengrui Xu

14 December 2025

Performance breakthroughs and safety assurance of aerospace equipment are critical to the advancement of modern aerospace technology. As a key protective system for the hot-end components of aeroengines, thermal barrier coatings (TBCs) play a vital r...

  • Article
  • Open Access
1 Citations
1,089 Views
13 Pages

25 January 2025

The low adhesion of water drops on superhydrophobic surfaces is a prerequisite for their widespread potential industrial applications. The wetting transition between different wetting states significantly influences the dynamic behavior of water drop...

  • Article
  • Open Access
4 Citations
4,460 Views
14 Pages

An Embryonic Zebrafish Model to Screen Disruption of Gut-Vascular Barrier upon Exposure to Ambient Ultrafine Particles

  • Kyung In Baek,
  • Yi Qian,
  • Chih-Chiang Chang,
  • Ryan O’Donnell,
  • Ehsan Soleimanian,
  • Constantinos Sioutas,
  • Rongsong Li and
  • Tzung K. Hsiai

19 November 2020

Epidemiological studies have linked exposure to ambient particulate matter (PM) with gastrointestinal (GI) diseases. Ambient ultrafine particles (UFP) are the redox-active sub-fraction of PM2.5, harboring elemental and polycyclic aromatic hydrocarbon...

  • Article
  • Open Access
1 Citations
1,221 Views
12 Pages

16 January 2025

The distribution of voids in ceramic topcoats (TC) and the micro-roughness of metallic bond coat (BC) interfaces are important for the structure design and coating life of thermal barrier coating (TBC) systems. In this study, finite elemental (FE) mo...

  • Review
  • Open Access
23 Citations
9,900 Views
17 Pages

Stem Cells behind the Barrier

  • Michael Cangkrama,
  • Stephen B. Ting and
  • Charbel Darido

28 June 2013

Epidermal stem cells sustain the adult skin for a lifetime through self-renewal and the production of committed progenitors. These stem cells generate progeny that will undergo terminal differentiation leading to the development of a protective epide...

  • Article
  • Open Access
49 Citations
7,474 Views
10 Pages

miR-24 Targets the Transmembrane Glycoprotein Neuropilin-1 in Human Brain Microvascular Endothelial Cells

  • Pasquale Mone,
  • Jessica Gambardella,
  • Xujun Wang,
  • Stanislovas S. Jankauskas,
  • Alessandro Matarese and
  • Gaetano Santulli

Neuropilin-1 is a transmembrane glycoprotein that has been implicated in several processes including angiogenesis and immunity. Recent evidence has also shown that it is implied in the cellular internalization of the severe acute respiratory syndrome...

  • Article
  • Open Access
2 Citations
739 Views
18 Pages

31 July 2025

The escalating environmental noise pollution along urban rail transit corridors, exacerbated by rapid urbanization, necessitates innovative and efficient noise control measures. A comprehensive investigation was conducted that utilized field measurem...

  • Article
  • Open Access
945 Views
12 Pages

12 August 2025

The long-term reliability of vacuum insulation panels (VIPs) is constrained by the barrier film degradation caused by micro-cracks during the flanging process. However, the correlation mechanism between process parameters and microleakage remains unc...

  • Article
  • Open Access
1,144 Views
14 Pages

30 April 2025

Bentonite is widely used as an engineering barrier in radioactive waste disposal. This study examined the hydromechanical behavior and microstructural evolution of a bentonite mixture under controlled hydration, utilizing real-time X-ray micro-CT ima...

  • Review
  • Open Access
23 Citations
6,994 Views
28 Pages

30 November 2021

Research on inflammatory bowel disease (IBD) has produced mounting evidence for the modulation of microRNAs (miRNAs) during pathogenesis. MiRNAs are small, non-coding RNAs that interfere with the translation of mRNAs. Their high stability in free cir...

  • Article
  • Open Access
16 Citations
2,969 Views
15 Pages

Direct Fabrication and Characterization of Zirconia Thick Coatings on Zirconium Hydride as a Hydrogen Permeation Barrier

  • Zhi-Gang Wang,
  • Wei-Dong Chen,
  • Shu-Fang Yan,
  • Xue-Kui Zhong,
  • Wen Ma,
  • Xi-Wen Song,
  • Ya-Ming Wang and
  • Jia-Hu Ouyang

The present work attempted to produce thick zirconia coatings formed by micro-arc oxidation as a hydrogen permeation barrier on zirconium hydride alloy. A novel multiphase zirconia coating was achieved, exhibiting superior hydrogen permeation barrier...

  • Article
  • Open Access
8 Citations
2,955 Views
13 Pages

Preparation and CMAS Wettability Investigation of CMAS Corrosion Resistant Protective Layer with Micro-Nano Double Scale Structure

  • Yihao Wang,
  • Zhenning Xu,
  • Weize Wang,
  • Chengcheng Zhang,
  • Zexin Yu,
  • Huanjie Fang and
  • Ting Yang

Solution precursor plasma spray (SPPS) can prepare thermal barrier coatings (TBCs) with nanostructures, which can modify the adhesion and wettability of molten silicate environmental deposits (CMAS) on the surface of TBCs, thereby improving the resis...

  • Review
  • Open Access
5 Citations
3,371 Views
19 Pages

Developmental Toxicity of Micro(Nano)Plastics (MNPs) Exposure in Mammals: A Mini-Review

  • Gongxiang Xia,
  • Teng Wan,
  • Zhuan Chen,
  • Cuiqing Liu and
  • Ran Li

19 March 2025

Micro(nano)plastics (MNPs) pose a significant threat to both ecological environments and human health. This review systematically examines the developmental toxicity of MNPs in mammals, with a particular focus on the impact of maternal and paternal e...

  • Communication
  • Open Access
7 Citations
3,495 Views
10 Pages

miR-4432 Targets FGFBP1 in Human Endothelial Cells

  • Roberta Avvisato,
  • Pasquale Mone,
  • Stanislovas S. Jankauskas,
  • Fahimeh Varzideh,
  • Urna Kansakar,
  • Jessica Gambardella,
  • Antonio De Luca,
  • Alessandro Matarese and
  • Gaetano Santulli

16 March 2023

MicroRNAs (miRs) are small non-coding RNAs that modulate the expression of several target genes. Fibroblast growth factor binding protein 1 (FGFBP1) has been associated with endothelial dysfunction at the level of the blood–brain barrier (BBB)....

  • Article
  • Open Access
23 Citations
8,839 Views
17 Pages

16 July 2016

The Mississippi (MS) barrier island chain along the northern Gulf of Mexico coastline is subject to rapid changes in habitat, geomorphology and elevation by natural and anthropogenic disturbances. The purpose of this study was to compare habitat type...

  • Article
  • Open Access
6 Citations
3,248 Views
13 Pages

29 March 2021

A novel static friction model for the unlubricated contact of random rough surfaces at micro/nano scale is presented. This model is based on the energy dissipation mechanism that states that changes in the potential of the surfaces in contact lead to...

  • Article
  • Open Access
21 Citations
4,421 Views
11 Pages

miR-142 Targets TIM-1 in Human Endothelial Cells: Potential Implications for Stroke, COVID-19, Zika, Ebola, Dengue, and Other Viral Infections

  • Urna Kansakar,
  • Jessica Gambardella,
  • Fahimeh Varzideh,
  • Roberta Avvisato,
  • Stanislovas S. Jankauskas,
  • Pasquale Mone,
  • Alessandro Matarese and
  • Gaetano Santulli

6 September 2022

T-cell immunoglobulin and mucin domain 1 (TIM-1) has been recently identified as one of the factors involved in the internalization of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human cells, in addition to angiotensin-convert...

  • Review
  • Open Access
9 Citations
3,529 Views
17 Pages

Spinal Cord Injury Management Based on Microglia-Targeting Therapies

  • Thomas Gabriel Schreiner,
  • Oliver Daniel Schreiner and
  • Romeo Cristian Ciobanu

8 May 2024

Spinal cord injury is a complicated medical condition both from the clinician’s point of view in terms of management and from the patient’s perspective in terms of unsatisfactory recovery. Depending on the severity, this disorder can be d...

  • Article
  • Open Access
500 Views
21 Pages

MicroRNA and Protein Biomarkers of Intestinal Permeability in the Assessment of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

  • Dominika Białek,
  • Ewa Wunsch,
  • Agnieszka Kempińska-Podhorodecka,
  • Joanna Abramczyk,
  • Adam Wunsch and
  • Katarzyna Kozłowska

24 November 2025

Intestinal barrier dysfunction and microRNA dysregulation are proposed contributors to progression of metabolic dysfunction-associated steatotic liver disease (MASLD). We aimed to assess selected protein and miRNA biomarkers of intestinal permeabilit...

  • Article
  • Open Access
3 Citations
1,155 Views
21 Pages

Antimicrobial and Physicochemical Properties of Hemicellulose-Based Films Incorporating Carvacrol

  • Syed Ammar Hussain,
  • Brajendra K. Sharma,
  • Phoebe X. Qi,
  • Madhav P. Yadav and
  • Tony Z. Jin

29 July 2025

Antimicrobial food packaging with natural antimicrobials and biodegradable polymers presents an innovative solution to mitigate microbial contamination, prolong freshness, reduce food waste, and alleviate environmental burden. This study developed an...

  • Article
  • Open Access
42 Citations
4,906 Views
15 Pages

Analysis of microRNAs in Exosomes of Breast Cancer Patients in Search of Molecular Prognostic Factors in Brain Metastases

  • Carolin J. Curtaz,
  • Leonie Reifschläger,
  • Linus Strähle,
  • Jonas Feldheim,
  • Julia J. Feldheim,
  • Constanze Schmitt,
  • Matthias Kiesel,
  • Saskia-Laureen Herbert,
  • Achim Wöckel and
  • Patrick Meybohm
  • + 1 author

Brain metastases are the most severe tumorous spread during breast cancer disease. They are associated with a limited quality of life and a very poor overall survival. A subtype of extracellular vesicles, exosomes, are sequestered by all kinds of cel...

  • Review
  • Open Access
15 Citations
4,749 Views
20 Pages

Role of the MicroRNAs in the Pathogenic Mechanism of Painful Symptoms in Long COVID: Systematic Review

  • Samuel Reyes-Long,
  • Jose Luis Cortés-Altamirano,
  • Cindy Bandala,
  • Karina Avendaño-Ortiz,
  • Herlinda Bonilla-Jaime,
  • Antonio Bueno-Nava,
  • Alberto Ávila-Luna,
  • Pedro Sánchez-Aparicio,
  • Denise Clavijo-Cornejo and
  • Ana Lilia Dotor-LLerena
  • + 2 authors

10 February 2023

The ongoing pandemic of COVID-19 has caused more than 6.7 million tragic deaths, plus, a large percentage of people who survived it present a myriad of chronic symptoms that last for at least 6 months; this has been named as long COVID. Some of the m...

  • Article
  • Open Access
69 Citations
17,806 Views
19 Pages

20 October 2022

Digital transformation empowers micro-, small-, and medium-sized enterprises (MSMEs) to rethink the way they make decisions and apply technology in meaningful and sustainable ways. The aim of this study is to investigate the main barriers to MSMEs&rs...

  • Article
  • Open Access
6 Citations
3,054 Views
13 Pages

Influence of Air-Barrier and Curing Light Distance on Conversion and Micro-Hardness of Dental Polymeric Materials

  • Lucian Toma Ciocan,
  • Elena Iuliana Biru,
  • Vlad Gabriel Vasilescu,
  • Jana Ghitman,
  • Ana-Roxana Stefan,
  • Horia Iovu and
  • Roxana Ilici

7 December 2022

This study aims to assess the conversion degree and hardness behavior of two new commercial dental restorative composites that have been submitted to light curing in different environments (air and glycerin, respectively) at various distances from th...

  • Article
  • Open Access
15 Citations
3,261 Views
12 Pages

28 July 2023

The possible toxicity caused by nanoplastics or microplastics on organisms has been extensively studied. However, the unavoidably combined effects of nanoplastics and microplastics on organisms, particularly intestinal toxicity, are rarely clear. Her...

  • Review
  • Open Access
37 Citations
8,200 Views
33 Pages

30 November 2021

Beneficial properties achieved by nanostructuring effects in materials have generated tremendous interests in applications in surface engineering, especially in thermal barrier coatings (TBC). Limitations in conventional TBC processing for gas turbin...

  • Article
  • Open Access
57 Citations
5,984 Views
13 Pages

14 January 2017

Improved energy efficiency has become a strategic issue and represents a priority for European competitiveness. Countries adopt various energy policies on local and national levels where energy audit programs are the most common energy end-use effici...

  • Article
  • Open Access
2 Citations
3,587 Views
14 Pages

Micro- and Nanofibrillated Cellulose Coatings as Barriers Against Water and Oil in Food Packaging Paper: A Sustainable Alternative to Plastic Coatings

  • Marcin Dubowik,
  • Kamila Przybysz,
  • Jacek Dańczak,
  • Aneta Lipkiewicz,
  • Marta Gajadhur,
  • Beata Górska,
  • Ewelina Pawłowska,
  • Robert Drozd and
  • Piotr Przybysz

24 February 2025

This research investigates the effectiveness of micro- and nanofibrillated cellulose (M-NFC) coatings compared to traditional synthetic coatings in enhancing the barrier properties of paper. Papers were coated at various grammages (1.2, 1.8, and 2.9...

  • Article
  • Open Access
7 Citations
3,539 Views
22 Pages

Mechanical Properties of Multi-Sized Porous Thermal Barrier Coatings at Micro and Nano Scales after Long-Term Service at High Temperature

  • Peihu Gao,
  • Shengcong Zeng,
  • Can Jin,
  • Bo Zhang,
  • Baiyang Chen,
  • Zhong Yang,
  • Yongchun Guo,
  • Minxian Liang,
  • Jianping Li and
  • Wei Wang
  • + 3 authors

28 January 2022

Atmospheric plasma-sprayed multi-sized porous structures in thermal barrier coatings (TBCs) were constructed with hollow spherical (HOSP) 8YSZ powders and polypropylene pore formers. The mechanical properties of the multi-sized TBCs were investigated...

  • Review
  • Open Access
1 Citations
1,407 Views
44 Pages

2 September 2025

This present review aims to provide a clear overview of the environmental impact of non-biodegradable materials, and the use of biodegradable materials as their replacements. Non-biodegradable polymers have been used in the past, and now they are con...

  • Article
  • Open Access
48 Citations
16,290 Views
28 Pages

11 July 2022

It is anticipated that e-commerce will contribute to achieving the 17th Sustainable Development Goal, which seeks to improve implementation mechanisms and revitalize global partnerships for sustainable development. However, MSMEs still face a digital...

  • Review
  • Open Access
10 Citations
5,793 Views
24 Pages

20 March 2024

Ischemic stroke is a fatal and disabling disease worldwide and imposes a significant burden on society. At present, biological markers that can be conveniently measured in body fluids are lacking for the diagnosis of ischemic stroke, and there are no...

  • Article
  • Open Access
5 Citations
1,526 Views
16 Pages

Micro-Nano Dual-Scale Coatings Prepared by Suspension Precursor Plasma Spraying for Resisting Molten Silicate Deposit

  • Yangguang Liu,
  • Yihao Wang,
  • Weize Wang,
  • Wenkang Zhang,
  • Junhao Wang,
  • Kaibin Li,
  • Hongchen Li,
  • Pengpeng Liu,
  • Shilong Yang and
  • Chengcheng Zhang

2 September 2024

Yb-doped Y2O3 stabilized ZrO2 (YbYSZ) coatings, developed through solution precursor plasma spraying (SPPS), are engineered to resist calcium–magnesium–alumino–silicate (CMAS) infiltration by leveraging their unique micro-nano struc...

  • Article
  • Open Access
17 Citations
5,699 Views
23 Pages

Transcryptomic Analysis of Human Brain-Microvascular Endothelial Response to -Pericytes: Cell Orientation Defines Barrier Function

  • Lisa Kurmann,
  • Michal Okoniewski,
  • Omolara O. Ogunshola,
  • Brigitte Leeners,
  • Bruno Imthurn and
  • Raghvendra K. Dubey

20 April 2021

Pericytes facilitate blood–brain barrier (BBB) integrity; however, the mechanisms involved remain unclear. Hence, using co-cultures of human cerebral microvascular endothelial cells (ECs) and vascular pericytes (PCs) in different spatial arrangements...

  • Review
  • Open Access
27 Citations
7,236 Views
35 Pages

Information on the penetration depth, pathways, metabolization, storage of vehicles, active pharmaceutical ingredients (APIs), and functional cosmetic ingredients (FCIs) of topically applied formulations or contaminants (substances) in skin is of gre...

  • Review
  • Open Access
97 Citations
12,266 Views
18 Pages

Genetic and Epigenetic Aspects of Atopic Dermatitis

  • Bogusław Nedoszytko,
  • Edyta Reszka,
  • Danuta Gutowska-Owsiak,
  • Magdalena Trzeciak,
  • Magdalena Lange,
  • Justyna Jarczak,
  • Marek Niedoszytko,
  • Ewa Jablonska,
  • Jan Romantowski and
  • Dominik Strapagiel
  • + 6 authors

4 September 2020

Atopic dermatitis is a heterogeneous disease, in which the pathogenesis is associated with mutations in genes encoding epidermal structural proteins, barrier enzymes, and their inhibitors; the role of genes regulating innate and adaptive immune respo...

  • Article
  • Open Access
37 Citations
5,825 Views
19 Pages

Brain metastases represent one of the incurable end stages in breast cancer (BC). Developing effective or preventive treatments is hampered by a lack of knowledge on the molecular mechanisms driving brain metastasis. Transmigration of BC cells throug...

  • Article
  • Open Access
30 Citations
4,458 Views
17 Pages

Breast cancer brain metastasis is a major clinical challenge and is associated with a dismal prognosis. Understanding the mechanisms underlying the early stages of brain metastasis can provide opportunities to develop efficient diagnostics and therap...

  • Article
  • Open Access
3 Citations
4,290 Views
10 Pages

A Simple, Low-Cost Micro-Coating Method for Accuracy Improvement and Its Application in Pressure Sensors

  • Jia-Lin Yao,
  • Yu-Xuan Chen,
  • Wen-Jiang Qiang,
  • Xi-Zi Wang,
  • Hao Wei,
  • Bo-Hang Gao and
  • Xing Yang

22 October 2019

The demand for high-accuracy pressure sensors has increased with the advancement of technology in a wide variety of applications. However, it is generally difficult and expensive to improve the accuracy of the pressure sensor because it usually depen...

  • Article
  • Open Access
39 Citations
5,852 Views
16 Pages

17 March 2020

Energy access remains a challenge for many countries, as recognized by sustainable development goal 7 of the United Nations Development Programme. Although the Myanmar government has set a target of 100% electrification by 2030, less than half of the...

  • Article
  • Open Access
1 Citations
3,099 Views
16 Pages

21 November 2021

Previous research on friction calculation models has mainly focused on static friction, whereas sliding friction calculation models are rarely reported. In this paper, a novel sliding friction model for realizing a dry spherical flat contact with a r...

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