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124 Results Found

  • Article
  • Open Access
2,956 Views
9 Pages

Effect of an Extremely Low-Frequency Electromagnetic Field on the Concentration of Salivary Immunoglobulin A

  • Piotr Skomro,
  • Danuta Lietz-Kijak,
  • Olga Bogdziewicz-Wałęsa and
  • Joanna Janiszewska-Olszowska

Extremely Low-Frequency Electromagnetic Field (ELF MF) therapy is effective in the treatment of injury, inflammation and postoperative complications. Its clinical applications relate to bone unification, pain reduction, soft tissue oedema and the dec...

  • Article
  • Open Access
15 Citations
3,083 Views
19 Pages

Thermomagnetic Resonance Effect of the Extremely Low Frequency Electromagnetic Field on Three-Dimensional Cancer Models

  • Loredana Bergandi,
  • Umberto Lucia,
  • Giulia Grisolia,
  • Iris Chiara Salaroglio,
  • Iacopo Gesmundo,
  • Riccarda Granata,
  • Romano Borchiellini,
  • Antonio Ponzetto and
  • Francesca Silvagno

In our recent studies, we have developed a thermodynamic biochemical model able to select the resonant frequency of an extremely low frequency electromagnetic field (ELF-EMF) specifically affecting different types of cancer, and we have demonstrated...

  • Article
  • Open Access
16 Citations
3,955 Views
12 Pages

Effect of Rehabilitation with Extremely Low Frequency Electromagnetic Field on Molecular Mechanism of Apoptosis in Post-Stroke Patients

  • Natalia Cichon,
  • Ewelina Synowiec,
  • Elzbieta Miller,
  • Tomasz Sliwinski,
  • Michal Ceremuga,
  • Joanna Saluk-Bijak and
  • Michal Bijak

Apoptosis in acute stroke is associated with a negative prognosis and is correlated with the severity of the neurological deficit. However, there is no evidence that indicates that, in the subacute phase of the stroke, the apoptosis process might act...

  • Article
  • Open Access
6 Citations
3,492 Views
7 Pages

30 April 2019

We previously showed that the agamid lizard Pogona vitticeps responded to an extremely low-frequency electromagnetic field (ELF-EMF; frequency: 6 and 8 Hz; peak magnetic field: 2.6 µT; peak electric field: 10 V/m) with tail-lifting behavior. In...

  • Article
  • Open Access
2,300 Views
21 Pages

Nowadays, the extremely-low-frequency electromagnetic field (ELF-EMF) is recognized as environmental pollution. The data indicate that the ELF-EMF may affect factors related to epigenetic regulation and alter important biological processes in the ute...

  • Article
  • Open Access
10 Citations
4,978 Views
19 Pages

Extremely Low-Frequency Electromagnetic Field (ELF-EMF) Increases Mitochondrial Electron Transport Chain Activities and Ameliorates Depressive Behaviors in Mice

  • Masaki Teranishi,
  • Mikako Ito,
  • Zhizhou Huang,
  • Yuki Nishiyama,
  • Akio Masuda,
  • Hiroyuki Mino,
  • Masako Tachibana,
  • Toshiya Inada and
  • Kinji Ohno

21 October 2024

Compromised mitochondrial electron transport chain (ETC) activities are associated with depression in humans and rodents. However, the effects of the enhancement of mitochondrial ETC activities on depression remain elusive. We recently reported that...

  • Study Protocol
  • Open Access
1,921 Views
16 Pages

30 April 2024

(1) Background: This study investigated the effects of sequenced electromagnetic fields, modulated at extremely low frequencies and intensities, in the treatment of drug-resistant Escherichia coli (E. coli)-induced chronic bacterial cystitis. (2) Met...

  • Article
  • Open Access
6 Citations
6,311 Views
10 Pages

For this investigation, we studied the effects of extremely low frequency pulse electromagnetic fields (ELF-PEMF) on the human cardiac signal. Electrocardiograms (ECGs) of 22 healthy volunteers before and after a short duration of ELF-PEMF exposure w...

  • Brief Report
  • Open Access
3 Citations
2,607 Views
11 Pages

Even though electromagnetic fields have been reported to assist endogenous neurogenesis, little is known about the exact mechanisms of their action. In this pilot study, we investigated the effects of pulsating extremely low-frequency electromagnetic...

  • Article
  • Open Access
21 Citations
7,589 Views
16 Pages

11 October 2017

This study evaluated frequency-dependent effects of extremely low frequency electromagnetic fields (ELF-EMFs) on melanogenesis by melanocytes in vitro. Melanocytes were exposed to 2 mT EMFs at 30–75 Hz for 3 days before melanogenesis was examined. Ex...

  • Review
  • Open Access
43 Citations
12,757 Views
22 Pages

Translational Insights into Extremely Low Frequency Pulsed Electromagnetic Fields (ELF-PEMFs) for Bone Regeneration after Trauma and Orthopedic Surgery

  • Sabrina Ehnert,
  • Steffen Schröter,
  • Romina H. Aspera-Werz,
  • Wiebke Eisler,
  • Karsten Falldorf,
  • Michael Ronniger and
  • Andreas K. Nussler

20 November 2019

The finding that alterations in electrical potential play an important role in the mechanical stimulation of the bone provoked hype that noninvasive extremely low frequency pulsed electromagnetic fields (ELF-PEMF) can be used to support healing of bo...

  • Article
  • Open Access
45 Citations
7,406 Views
14 Pages

Co-Culture with Human Osteoblasts and Exposure to Extremely Low Frequency Pulsed Electromagnetic Fields Improve Osteogenic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells

  • Sabrina Ehnert,
  • Martijn Van Griensven,
  • Marina Unger,
  • Hanna Scheffler,
  • Karsten Falldorf,
  • Anne-Kristin Fentz,
  • Claudine Seeliger,
  • Steffen Schröter,
  • Andreas K. Nussler and
  • Elizabeth R. Balmayor

Human adipose-derived mesenchymal stem cells (Ad-MSCs) have been proposed as suitable option for cell-based therapies to support bone regeneration. In the bone environment, Ad-MSCs will receive stimuli from resident cells that may favor their osteoge...

  • Article
  • Open Access
4 Citations
3,053 Views
15 Pages

The Effect of Extremely Low-Frequency Electromagnetic Fields on Inflammation and Performance-Related Indices in Trained Athletes: A Double-Blinded Crossover Study

  • Irit Markus,
  • Evyatar Ohayon,
  • Keren Constantini,
  • Keren Geva-Kleinberger,
  • Rawan Ibrahim,
  • Angela Ruban and
  • Yftach Gepner

30 August 2023

Previous investigations have demonstrated the therapeutic advantages of extremely low-frequency electromagnetic fields (ELF-EMFs) in mitigating inflammation and influencing biological processes. We aimed to shed light on the effects of ELF-EMF on rec...

  • Article
  • Open Access
17 Citations
6,390 Views
13 Pages

The Effect of an Extremely Low-Frequency Electromagnetic Field on the Drought Sensitivity of Wheat Plants

  • N. S. Mshenskaya,
  • M. A. Grinberg,
  • E. A. Kalyasova,
  • V. A. Vodeneev,
  • N. V. Ilin,
  • N. N. Slyunyaev,
  • E. A. Mareev and
  • Y. V. Sinitsyna

13 February 2023

Extremely low-frequency magnetic fields are thought to be capable of modulating the resistance of plants to adverse factors, particularly drought. Magnetic fields in this frequency range occur in nature in connection with so-called Schumann resonance...

  • Article
  • Open Access
25 Citations
3,923 Views
12 Pages

The Influence of the Extremely Low Frequency Electromagnetic Field on Clear Cell Renal Carcinoma

  • Aleksandra Cios,
  • Martyna Ciepielak,
  • Wanda Stankiewicz and
  • Łukasz Szymański

29 January 2021

The development of new technologies and industry is conducive to the increase in the number and variety of electromagnetic field (EMF) sources in our environment. The main sources of EMF are high-voltage lines, household appliances, audio/video devic...

  • Review
  • Open Access
45 Citations
8,360 Views
13 Pages

Wound healing is a complex, staged process. It involves extensive communication between the different cellular constituents of various compartments of the skin and its extracellular matrix (ECM). Different signaling pathways are determined by a mutua...

  • Article
  • Open Access
2 Citations
4,210 Views
23 Pages

22 December 2024

Background/Objectives: Autism Spectrum Disorder (ASD) are neurodevelopmental disorders marked by challenges in social interaction, communication, and repetitive behaviors. People with ASD may exhibit repetitive behaviors, unique ways of learning, and...

  • Editorial
  • Open Access
31 Citations
6,021 Views
6 Pages

18 September 2018

Modern technology has largely developed using energy forms of which the most relevant is surely electricity. Electric power stations generate alternate current at frequencies of 50 or 60 Hz, transmitted across high voltage transmission lines that are...

  • Article
  • Open Access
1 Citations
2,943 Views
16 Pages

23 April 2023

The controlled source extremely low frequency (CSELF) method bears the potential for deep resource exploitation utilizing the skywave. The “Skywave” denotes the electromagnetic wave propagating through the waveguide formed by the Earth an...

  • Review
  • Open Access
1 Citations
976 Views
28 Pages

Magnetic fields (MFs), including static (SMFs) and extremely low-frequency electromagnetic fields (ELF-EMFs), have recently emerged as potential modulators of anticancer drug responses. Evidence indicates that MFs can influence membrane transport, ox...

  • Article
  • Open Access
1 Citations
6,666 Views
21 Pages

Utilizing the Exergy Concept to Address Environmental Challenges of Electric Systems

  • Cornelia A. Bulucea,
  • Marc A. Rosen,
  • Doru A. Nicola,
  • Nikos E. Mastorakis and
  • Carmen A. Bulucea

11 October 2012

Theoretically, the concepts of energy, entropy, exergy and embodied energy are founded in the fields of thermodynamics and physics. Yet, over decades these concepts have been applied in numerous fields of science and engineering, playing a key role i...

  • Article
  • Open Access
38 Citations
5,397 Views
14 Pages

Short ELF-EMF Exposure Targets SIRT1/Nrf2/HO-1 Signaling in THP-1 Cells

  • Antonia Patruno,
  • Erica Costantini,
  • Alessio Ferrone,
  • Mirko Pesce,
  • Francesca Diomede,
  • Oriana Trubiani and
  • Marcella Reale

2 October 2020

Extremely low frequency electromagnetic fields (ELF-EMFs) have been known to modulate inflammatory responses by targeting signal transduction pathways and influencing cellular redox balance through the generation of oxidants and antioxidants. Here, w...

  • Case Report
  • Open Access
6 Citations
2,834 Views
9 Pages

Modern high-resolution volumetric tomography, commonly known as cone beam computed tomography (CBCT), is one of the most innovative imaging techniques which can provide views of anatomical structures not attainable by conventional techniques. Magneti...

  • Review
  • Open Access
141 Citations
41,600 Views
33 Pages

Concomitant with the ever-expanding use of electrical appliances and mobile communication systems, public and occupational exposure to electromagnetic fields (EMF) in the extremely-low-frequency and radiofrequency range has become a widely debated en...

  • Article
  • Open Access
2,213 Views
12 Pages

22 August 2024

A general theory explaining how electromagnetic waves affect cells and biological systems has not been completely accepted yet; nevertheless, extremely low-frequency electromagnetic fields (ELF-EMFs) can interfere with and modify several molecular ce...

  • Article
  • Open Access
2,343 Views
11 Pages

Use of Electrical Household Appliances and Risk of All Types of Tumours: A Case-Control Study

  • Shabana Noori,
  • Abdul Aleem,
  • Imrana Niaz Sultan,
  • Afrasiab Khan Tareen,
  • Hayat Ullah and
  • Muhammad Waseem Khan

Introduction: The use of electrical appliances using extremely low frequency (ELF) electromagnetic fields (EMF) has increased in the past few years. These ELF MF are reported to be linked to several adverse health effects. However, only a couple of s...

  • Brief Report
  • Open Access
6 Citations
3,084 Views
18 Pages

A Novel Method to Achieve Precision and Reproducibility in Exposure Parameters for Low-Frequency Pulsed Magnetic Fields in Human Cell Cultures

  • Michael Ronniger,
  • Blanche Aguida,
  • Christina Stacke,
  • Yangmengfan Chen,
  • Sabrina Ehnert,
  • Niklas Erdmann,
  • Georg Eschenburg,
  • Karsten Falldorf,
  • Marootpong Pooam and
  • Anthony Wing
  • + 1 author

The effects of extremely low-frequency electromagnetic field (ELF-MF) exposure on living systems have been widely studied at the fundamental level and also claimed as beneficial for the treatment of diseases for over 50 years. However, the underlying...

  • Article
  • Open Access
20 Citations
4,217 Views
16 Pages

Modulation of Macrophage Activity by Pulsed Electromagnetic Fields in the Context of Fracture Healing

  • Yangmengfan Chen,
  • Maximilian M. Menger,
  • Benedikt J. Braun,
  • Sara Schweizer,
  • Caren Linnemann,
  • Karsten Falldorf,
  • Michael Ronniger,
  • Hongbo Wang,
  • Tina Histing and
  • Andreas K. Nussler
  • + 1 author

Delayed fracture healing and fracture non-unions impose an enormous burden on individuals and society. Successful healing requires tight communication between immune cells and bone cells. Macrophages can be found in all healing phases. Due to their h...

  • Article
  • Open Access
3 Citations
3,930 Views
9 Pages

15 March 2020

In a previous study, the agamid lizard Pogona vitticeps was discovered to respond to an electromagnetic field (EMF) of extremely low frequency (6 and 8 Hz; peak magnetic and electric fields of 2.6 µT and 10 V/m, respectively). Furthermore, when...

  • Article
  • Open Access
6 Citations
3,450 Views
13 Pages

Extremely Low-Frequency Electromagnetic Field Impairs the Development of Honeybee (Apis cerana)

  • Yingjiao Li,
  • Chaoxia Sun,
  • He Zhou,
  • Hongji Huang,
  • Yijie Chen,
  • Xinle Duan,
  • Shaokang Huang and
  • Jianghong Li

14 September 2022

Increasing ELF-EMF pollution in the surrounding environment could impair the cognition and learning ability of honeybees, posing a threat to the honeybee population and its pollination ability. In a social honeybee colony, the numbers of adult bees r...

  • Article
  • Open Access
15 Citations
3,754 Views
13 Pages

Intermittent Exposure to a 16 Hz Extremely Low Frequency Pulsed Electromagnetic Field Promotes Osteogenesis In Vitro through Activating Piezo 1-Induced Ca2+ Influx in Osteoprogenitor Cells

  • Yangmengfan Chen,
  • Benedikt J. Braun,
  • Maximilian M. Menger,
  • Michael Ronniger,
  • Karsten Falldorf,
  • Tina Histing,
  • Andreas K. Nussler and
  • Sabrina Ehnert

Exposure to extremely low frequency pulsed electromagnetic fields (ELF-PEMF) is supposed to simulate local EMF generated during mechanical stimulation of bone and may therefore be used to improve bone regeneration. This study aimed at optimizing the...

  • Article
  • Open Access
13 Citations
3,419 Views
15 Pages

Exposure to 16 Hz Pulsed Electromagnetic Fields Protect the Structural Integrity of Primary Cilia and Associated TGF-β Signaling in Osteoprogenitor Cells Harmed by Cigarette Smoke

  • Yangmengfan Chen,
  • Romina H. Aspera-Werz,
  • Maximilian M. Menger,
  • Karsten Falldorf,
  • Michael Ronniger,
  • Christina Stacke,
  • Tina Histing,
  • Andreas K. Nussler and
  • Sabrina Ehnert

Cigarette smoking (CS) is one of the main factors related to avoidable diseases and death across the world. Cigarette smoke consists of numerous toxic compounds that contribute to the development of osteoporosis and fracture nonunion. Exposure to pul...

  • Article
  • Open Access
16 Citations
6,751 Views
14 Pages

Pulsed Electromagnetic Field Therapy Improves Osseous Consolidation after High Tibial Osteotomy in Elderly Patients—A Randomized, Placebo-Controlled, Double-Blind Trial

  • Patrick Ziegler,
  • Andreas K. Nussler,
  • Benjamin Wilbrand,
  • Karsten Falldorf,
  • Fabian Springer,
  • Anne-Kristin Fentz,
  • Georg Eschenburg,
  • Andreas Ziegler,
  • Ulrich Stöckle and
  • Elke Maurer
  • + 3 authors

17 November 2019

Extremely low-frequency pulsed electromagnetic field (ELF-PEMF) therapy is proposed to support bone healing after injuries and surgical procedures, being of special interest for elderly patients. This study aimed at investigating the effect of a spec...

  • Article
  • Open Access
3 Citations
2,401 Views
9 Pages

Searching for the Mechanism of Action of Extremely Low Frequency Electromagnetic Field—The Pilot fNIRS Research

  • Karolina Jezierska,
  • Anna Sękowska-Namiotko,
  • Bartłomiej Pala,
  • Danuta Lietz-Kijak,
  • Helena Gronwald and
  • Wojciech Podraza

There is an ongoing debate on the benefits of magnetic stimulation in neurological disorders. Objectives: We aimed to evaluate the influence of magnetic stimulation on blood oxygenation of the motor cortex using functional near-infrared spectroscopy...

  • Article
  • Open Access
38 Citations
5,033 Views
17 Pages

Human Gingival Fibroblasts Exposed to Extremely Low-Frequency Electromagnetic Fields: In Vitro Model of Wound-Healing Improvement

  • Erica Costantini,
  • Bruna Sinjari,
  • Chiara D’Angelo,
  • Giovanna Murmura,
  • Marcella Reale and
  • Sergio Caputi

Several clinical studies have suggested the impact of sinusoidal and pulsed electromagnetic fields in quickening wound repair processes and tissue regeneration. The clinical use of extremely low-frequency electromagnetic fields could represent a nove...

  • Article
  • Open Access
6 Citations
2,574 Views
14 Pages

7 October 2023

The technologies of undersea detection and communication, seabed sensor networks, and geophysical detection using electromagnetic waves have emerged as research focal points within the field of marine science and engineering. However, most studies ha...

  • Review
  • Open Access
2,416 Views
27 Pages

7 August 2025

This study presents a comprehensive evaluation and selection framework for extremely low-frequency electromagnetic field (ELF-EMF) measurement instruments. Recognizing the diversity of application environments and technical constraints, the framework...

  • Review
  • Open Access
187 Citations
12,521 Views
20 Pages

18 October 2017

Reactive oxygen species (ROS) ubiquitously exist in mammalian cells to participate in various cellular signaling pathways. The intracellular ROS levels are dependent on the dynamic balance between ROS generation and elimination. In this review, we su...

  • Article
  • Open Access
16 Citations
4,593 Views
13 Pages

CT2A Cell Viability Modulated by Electromagnetic Fields at Extremely Low Frequency under No Thermal Effects

  • Olga García-Minguillán,
  • Raquel Prous,
  • Maria del Carmen Ramirez-Castillejo and
  • Ceferino Maestú

24 December 2019

The effects produced by electromagnetic fields (EMFs) on human beings at extremely low frequencies (ELFs) have being investigated in the past years, across in vitro studies, using different cell lines. Nevertheless, the effects produced on cells are...

  • Article
  • Open Access
8 Citations
5,721 Views
13 Pages

Background: Spinal cord injury (SCI) pathology includes both primary and secondary events. The primary injury includes the original traumatic event, and the secondary injury, beginning immediately after the initial injury, involves progressive neuroi...

  • Article
  • Open Access
8 Citations
3,886 Views
15 Pages

Innate immune cells react to electromagnetic fields (EMF) by generating reactive oxygen species (ROS), crucial intracellular messengers. Discrepancies in applied parameters of EMF studies, e.g., flux densities, complicate direct comparison of downstr...

  • Article
  • Open Access
4 Citations
3,643 Views
17 Pages

50 Hz Temporal Magnetic Field Monitoring from High-Voltage Power Lines: Sensor Design and Experimental Validation

  • Kenneth Deprez,
  • Tom Van de Steene,
  • Leen Verloock,
  • Emmeric Tanghe,
  • Liesbeth Gommé,
  • Mart Verlaek,
  • Michel Goethals,
  • Karen van Campenhout,
  • David Plets and
  • Wout Joseph

17 August 2024

A low-cost, tri-axial 50 Hz magnetic field monitoring sensor was designed, calibrated and verified. The sensor was designed using off-the-shelf components and commercially available coils. It can measure 50 Hz magnetic fields originating from high-vo...

  • Article
  • Open Access
4 Citations
7,309 Views
16 Pages

Hair loss is a chronic disorder that affects many people; however, a complete treatment has not yet been developed. Therefore, new therapeutic agents for preventing hair loss must be developed, and electromagnetic field (EMF) therapy has been proven...

  • Article
  • Open Access
6 Citations
2,439 Views
17 Pages

NET Formation Was Reduced via Exposure to Extremely Low-Frequency Pulsed Electromagnetic Fields

  • Caren Linnemann,
  • Filiz Sahin,
  • Yangmengfan Chen,
  • Karsten Falldorf,
  • Michael Ronniger,
  • Tina Histing,
  • Andreas K. Nussler and
  • Sabrina Ehnert

27 September 2023

Fracture-healing is a highly complex and timely orchestrated process. Non-healing fractures are still a major clinical problem and treatment remains difficult. A 16 Hz extremely low-frequency pulsed electromagnetic field (ELF-PEMF) was identified as...

  • Review
  • Open Access
18 Citations
16,727 Views
19 Pages

The Critical Importance of Molecular Biomarkers and Imaging in the Study of Electrohypersensitivity. A Scientific Consensus International Report

  • Dominique Belpomme,
  • George L. Carlo,
  • Philippe Irigaray,
  • David O. Carpenter,
  • Lennart Hardell,
  • Michael Kundi,
  • Igor Belyaev,
  • Magda Havas,
  • Franz Adlkofer and
  • Gunnar Heuser
  • + 22 authors

Clinical research aiming at objectively identifying and characterizing diseases via clinical observations and biological and radiological findings is a critical initial research step when establishing objective diagnostic criteria and treatments. Fai...

  • Article
  • Open Access
2,628 Views
11 Pages

19 April 2021

Nondestructive evaluation of various conductive objects through metal enclosures is investigated by using ELF/VLF magnetic induction fields in detailed simulations. ELF/VLF magnetic fields (<30 kHz) have a unique ability to penetrate highly conduc...

  • Systematic Review
  • Open Access
2 Citations
3,475 Views
17 Pages

Background: The aim of this study was to review the current state of scientific evidence on the effect of extremely low-frequency magnetic fields stimulation (ELF-MFs) on stroke patients. Methods: A systematic review of PubMed, ScienceDirect, PeDro a...

  • Review
  • Open Access
11 Citations
5,669 Views
31 Pages

Progress in the Knowledge, Application and Influence of Extremely Low Frequency Signals

  • Rosa M. García,
  • Nuria Novas,
  • Alfredo Alcayde,
  • Dalia El Khaled,
  • Manuel Fernández-Ros and
  • José Antonio Gazquez

18 May 2020

This paper describes the characteristics of contributions made by researchers worldwide in the field of ELF (extremely low frequency) waves from 1957 to 2019. The data were collected through the Scopus database and processed with analytical and bibli...

  • Article
  • Open Access
1 Citations
2,633 Views
11 Pages

14 March 2025

Background: Strokes are a major public health concern, responsible for high mortality and long-term disability rates. Rehabilitation techniques aim to harness neuroplasticity—brain self-repair mechanisms that restore lost functions. Beyond trad...

  • Article
  • Open Access
1,020 Views
11 Pages

The Antimicrobial Effect of a Low-Frequency Square Wave Compared to Chlorhexidine

  • Jin-Won Choi,
  • Seon-Mi Byeon,
  • Da-Hyun Lee,
  • Pil-Young Yun and
  • Jeong-Kui Ku

2 April 2025

Background/Objectives: Oral health is critical for overall health, particularly in hospitalized patients whose weakened physical state can lead to oral changes, such as dry mouth and gingivitis due to anxiety and stress. Neglected oral hygiene can le...

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