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  • Article
  • Open Access
5 Citations
2,351 Views
14 Pages

Enhanced Image Processing Using Complex Averaging in Diffusion-Weighted Imaging of the Prostate: The Impact on Image Quality and Lesion Detectability

  • Sebastian Werner,
  • Dominik Zinsser,
  • Michael Esser,
  • Dominik Nickel,
  • Konstantin Nikolaou and
  • Ahmed E. Othman

Diffusion-weighted images of the prostate can suffer from a “hazy” background in low signal-intensity areas. We hypothesize that enhanced image processing (EIP) using complex averaging reduces artifacts, noise, and distortion in conventio...

  • Article
  • Open Access
1 Citations
1,357 Views
12 Pages

Assessing Image Quality in Multiplexed Sensitivity-Encoding Diffusion-Weighted Imaging with Deep Learning-Based Reconstruction in Bladder MRI

  • Seung Ha Cha,
  • Yeo Eun Han,
  • Na Yeon Han,
  • Min Ju Kim,
  • Beom Jin Park,
  • Ki Choon Sim,
  • Deuk Jae Sung,
  • Seulki Yoo,
  • Patricia Lan and
  • Arnaud Guidon

28 February 2025

Background/Objectives: This study compared the image quality of conventional multiplexed sensitivity-encoding diffusion-weighted imaging (MUSE-DWI) and deep learning MUSE-DWI with that of vendor-specific deep learning (DL) reconstruction applied to b...

  • Review
  • Open Access
145 Citations
14,286 Views
28 Pages

Diffusion-Weighted Imaging in Oncology: An Update

  • Carmelo Messina,
  • Rodolfo Bignone,
  • Alberto Bruno,
  • Antonio Bruno,
  • Federico Bruno,
  • Marco Calandri,
  • Damiano Caruso,
  • Pietro Coppolino,
  • Riccardo De Robertis and
  • on behalf of the Young SIRM Working Group
  • + 7 authors

8 June 2020

To date, diffusion weighted imaging (DWI) is included in routine magnetic resonance imaging (MRI) protocols for several cancers. The real additive role of DWI lies in the “functional” information obtained by probing the free diffusivity of water mole...

  • Review
  • Open Access
9 Citations
6,272 Views
14 Pages

Brain Imaging in Epilepsy-Focus on Diffusion-Weighted Imaging

  • Tzu-Hsin Huang,
  • Ming-Chi Lai,
  • Yu-Shiue Chen and
  • Chin-Wei Huang

27 October 2022

Epilepsy is a common neurological disorder; 1% of people worldwide have epilepsy. Differentiating epileptic seizures from other acute neurological disorders in a clinical setting can be challenging. Approximately one-third of patients have drug-resis...

  • Article
  • Open Access
4 Citations
2,718 Views
18 Pages

Retrospective Motion Artifact Reduction by Spatial Scaling of Liver Diffusion-Weighted Images

  • Johannes Raspe,
  • Felix N. Harder,
  • Selina Rupp,
  • Sean McTavish,
  • Johannes M. Peeters,
  • Kilian Weiss,
  • Marcus R. Makowski,
  • Rickmer F. Braren,
  • Dimitrios C. Karampinos and
  • Anh T. Van

6 October 2023

Cardiac motion causes unpredictable signal loss in respiratory-triggered diffusion-weighted magnetic resonance imaging (DWI) of the liver, especially inside the left lobe. The left liver lobe may thus be frequently neglected in the clinical evaluatio...

  • Article
  • Open Access
8 Citations
3,486 Views
15 Pages

Clinical Feasibility of Reduced Field-of-View Diffusion-Weighted Magnetic Resonance Imaging with Computed Diffusion-Weighted Imaging Technique in Breast Cancer Patients

  • Eun Cho,
  • Jin Hwa Lee,
  • Hye Jin Baek,
  • Ji Young Ha,
  • Kyeong Hwa Ryu,
  • Sung Eun Park,
  • Jin Il Moon,
  • Sung-Min Gho and
  • Tetsuya Wakayama

Background: We evaluated the feasibility of the reduced field-of-view (rFOV) diffusion-weighted imaging (DWI) with computed DWI technique by comparison and analysis of the inter-method agreement among acquired rFOV DWI (rFOVA), rFOV DWI with computed...

  • Review
  • Open Access
22 Citations
7,136 Views
19 Pages

Utility of the Diffusion Weighted Sequence in Gynecological Imaging: Review Article

  • Apurva Bonde,
  • Eduardo Andreazza Dal Lago,
  • Bryan Foster,
  • Sanaz Javadi,
  • Sarah Palmquist and
  • Priya Bhosale

15 September 2022

Functional imaging with diffusion-weighted imaging (DWI) is a complementary tool to conventional diagnostic magnetic resonance imaging sequences. It is being increasingly investigated to predict tumor response and assess tumor recurrence. We elucidat...

  • Article
  • Open Access
3 Citations
1,342 Views
10 Pages

Microstructure Modeling of High b-Value Diffusion-Weighted Images in Glioblastoma

  • Yuan Li,
  • Michelle Kim,
  • Theodore S. Lawrence,
  • Hemant Parmar and
  • Yue Cao

Apparent diffusion coefficient has limits to differentiate solid tumor from normal tissue or edema in glioblastoma (GBM). This study investigated a microstructure model (MSM) in GBM using a clinically available diffusion imaging technique. The MSM wa...

  • Article
  • Open Access
21 Citations
4,844 Views
10 Pages

Diffusion-Weighted Imaging Can Differentiate between Malignant and Benign Pleural Diseases

  • Katsuo Usuda,
  • Shun Iwai,
  • Aika Funasaki,
  • Atsushi Sekimura,
  • Nozomu Motono,
  • Munetaka Matoba,
  • Mariko Doai,
  • Sohsuke Yamada,
  • Yoshimichi Ueda and
  • Hidetaka Uramoto

12 June 2019

It is not clear whether magnetic resonance imaging (MRI) is useful for the assessment of pleural diseases. The aim of this study is to determine whether diffusion-weighted magnetic resonance imaging (DWI) can differentiate malignant pleural mesotheli...

  • Article
  • Open Access
1 Citations
2,389 Views
16 Pages

Diffusion-Weighted Imaging for Skin Pathologies of the Breast—A Feasibility Study

  • Dominika Skwierawska,
  • Frederik B. Laun,
  • Evelyn Wenkel,
  • Lorenz A. Kapsner,
  • Rolf Janka,
  • Michael Uder,
  • Sabine Ohlmeyer and
  • Sebastian Bickelhaupt

Several breast pathologies can affect the skin, and clinical pathways might differ significantly depending on the underlying diagnosis. This study investigates the feasibility of using diffusion-weighted imaging (DWI) to differentiate skin pathologie...

  • Review
  • Open Access
13 Citations
13,150 Views
21 Pages

Diffusion-weighted imaging (DWI) with an apparent diffusion coefficient (ADC) value is a relatively new magnetic resonance imaging (MRI) sequence that provides functional information on the lesion by measuring the microscopic movement of water molecu...

  • Article
  • Open Access
2,789 Views
15 Pages

Diffusion-Weighted MR Imaging of the Thymus in Children with Non-Thymic Neoplasms

  • Sook Min Hwang,
  • Ji Eun Park,
  • So-Young Yoo,
  • Ji Hye Kim,
  • Sun-Young Baek,
  • Sung-Hoon Moon and
  • Tae Yeon Jeon

13 December 2023

Purpose: To investigate the diffusion-weighted imaging (DWI) findings and apparent diffusion coefficient (ADC) value of the thymus in children under the age of 13 who have non-thymic neoplasms. Materials and Methods: From January 2021 to April 2023,...

  • Article
  • Open Access
15 Citations
3,439 Views
14 Pages

Combination Assessment of Diffusion-Weighted Imaging and T2-Weighted Imaging Is Acceptable for the Differential Diagnosis of Lung Cancer from Benign Pulmonary Nodules and Masses

  • Katsuo Usuda,
  • Masahito Ishikawa,
  • Shun Iwai,
  • Yoshihito Iijima,
  • Nozomu Motono,
  • Munetaka Matoba,
  • Mariko Doai,
  • Keiya Hirata and
  • Hidetaka Uramoto

28 March 2021

The purpose of this study is to determine whether the combination assessment of DWI and T2-weighted imaging (T2WI) improves the diagnostic ability for differential diagnosis of lung cancer from benign pulmonary nodules and masses (BPNMs). The optimal...

  • Article
  • Open Access
6 Citations
3,654 Views
15 Pages

Whole Process of Standardization of Diffusion-Weighted Imaging: Phantom Validation and Clinical Application According to the QIBA Profile

  • Se Jin Choi,
  • Kyung Won Kim,
  • Yousun Ko,
  • Young Chul Cho,
  • Ji Sung Jang,
  • Hyemin Ahn,
  • Dong Wook Kim and
  • Mi Young Kim

Background: To use the apparent diffusion coefficient (ADC) as reliable biomarkers, validation of MRI equipment performance and clinical acquisition protocols should be performed prior to application in patients. This study aims to validate various M...

  • Article
  • Open Access
913 Views
12 Pages

Combined Use of Diffusion- and Perfusion-Weighted Magnetic Resonance Imaging in the Differential Diagnosis of Sellar Tumors: A Single-Centre Experience

  • Adrian Korbecki,
  • Marek Łukasiewicz,
  • Arkadiusz Kacała,
  • Michał Sobański,
  • Agata Zdanowicz-Ratajczyk,
  • Karolina Szałata,
  • Mateusz Dorochowicz,
  • Justyna Korbecka,
  • Grzegorz Trybek and
  • Joanna Bladowska
  • + 1 author

11 October 2025

Background/Objectives: To evaluate whether incorporating both diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) in pituitary MRI examinations improves differential diagnosis by providing additional diagnostic value. Methods: A ret...

  • Article
  • Open Access
4 Citations
3,968 Views
11 Pages

Motion-Corrected versus Conventional Diffusion-Weighted Magnetic Resonance Imaging of the Liver Using Non-Rigid Registration

  • Je Seung Son,
  • Hee Sun Park,
  • Sungeun Park,
  • Young Jun Kim,
  • Mi Hye Yu,
  • Sung Il Jung,
  • Munyoung Paek and
  • Marcel Dominik Nickel

It is challenging to overcome motion artifacts in diffusion-weighted imaging (DWI) of the abdomen. This study aimed to evaluate the image quality of motion-corrected DWI of the liver using non-rigid registration in comparison with conventional DWI (c...

  • Article
  • Open Access
2 Citations
3,012 Views
11 Pages

Role of Diffusion-Weighted Magnetic Resonance Imaging for Characterization of Mediastinal Lymphadenopathy

  • Eniyavel Ramamoorthy,
  • Mandeep Garg,
  • Paramjeet Singh,
  • Ashutosh N. Aggarwal and
  • Nalini Gupta

13 February 2023

Background: To assess the diagnostic performance of diffusion-weighted (DW) magnetic resonance imaging (MRI) in the characterization of mediastinal lymph nodes and compare them with morphological parameters. Methods: A total of 43 untreated patients...

  • Review
  • Open Access
56 Citations
13,483 Views
11 Pages

Whole-Body MRI with Diffusion-Weighted Imaging in Bone Metastases: A Narrative Review

  • Alessandro Stecco,
  • Alessandra Trisoglio,
  • Eleonora Soligo,
  • Sara Berardo,
  • Lidiia Sukhovei and
  • Alessandro Carriero

Whole body magnetic resonance imaging (MRI) with diffusion-weighted imaging (WB-MRI-DWI) is currently emerging as a diagnostic technique in the evaluation of bone metastases from breast, prostate, lung, thyroid, and melanoma tumors. The most relevant...

  • Article
  • Open Access
14 Citations
3,254 Views
11 Pages

ADC-Based Stratification of Molecular Glioma Subtypes Using High b-Value Diffusion-Weighted Imaging

  • Nils C. Nuessle,
  • Felix Behling,
  • Ghazaleh Tabatabai,
  • Salvador Castaneda Vega,
  • Jens Schittenhelm,
  • Ulrike Ernemann,
  • Uwe Klose and
  • Johann-Martin Hempel

4 August 2021

Purpose: To investigate the diagnostic performance of in vivo ADC-based stratification of integrated molecular glioma grades. Materials and methods: Ninety-seven patients with histopathologically confirmed glioma were evaluated retrospectively. All p...

  • Article
  • Open Access
25 Citations
1,960 Views
11 Pages

Repeatability of Quantitative Diffusion-Weighted Imaging Metrics in Phantoms, Head-and-Neck and Thyroid Cancers: Preliminary Findings

  • Ramesh Paudyal,
  • Amaresha Shridhar Konar,
  • Nancy A. Obuchowski,
  • Vaios Hatzoglou,
  • Thomas L. Chenevert,
  • Dariya I. Malyarenko,
  • Scott D. Swanson,
  • Eve LoCastro,
  • Sachin Jambawalikar and
  • Amita Shukla-Dave
  • + 4 authors

The aim of this study was to establish the repeatability measures of quantitative Gaussian and non-Gaussian diffusion metrics using diffusion-weighted imaging (DWI) data from phantoms and patients with head-and-neck and papillary thyroid cancers. The...

  • Article
  • Open Access
2,695 Views
15 Pages

Comparison of Diagnostic Performance and Image Quality between Topup-Corrected and Standard Readout-Segmented Echo-Planar Diffusion-Weighted Imaging for Cholesteatoma Diagnostics

  • Marco Wiesmueller,
  • Wolfgang Wuest,
  • Angelika Mennecke,
  • Matthias Stefan May,
  • Rafael Heiss,
  • Tobit Fuehres,
  • Rolf Janka,
  • Michael Uder,
  • Arnd Doerfler and
  • Frederik Bernd Laun

This study compares the diagnostic performance and image quality of single-shot turbo spin-echo DWI (tseDWI), standard readout-segmented DWI (rsDWI), and a modified rsDWI version (topupDWI) for cholesteatoma diagnostics. Thirty-four patients with new...

  • Article
  • Open Access
4 Citations
2,521 Views
10 Pages

Diffusion-Weighted MRI as a Quantitative Imaging Biomarker in Colon Tumors

  • Peter Obel Otto,
  • Martina Kastrup Loft,
  • Søren Rafael Rafaelsen and
  • Malene Roland Vils Pedersen

27 December 2023

Purpose: To assess the use of quantitative diffusion-weighted MRI (DW-MRI) as a diagnostic imaging biomarker in differentiating between benign colon adenoma, early, and advanced cancer of the colon, as well as predicting lymph node involvement, and f...

  • Article
  • Open Access
13 Citations
1,713 Views
10 Pages

Comparison between 3-Scan Trace and Diagonal Body Diffusion-Weighted Imaging Acquisitions: A Phantom and Volunteer Study

  • Stefanie J. Hectors,
  • Mathilde Wagner,
  • Idoia Corcuera-Solano,
  • Martin Kang,
  • Alto Stemmer,
  • Michael A. Boss and
  • Bachir Taouli

1 December 2016

Diagonal diffusion-weighted imaging (dDWI) uses simultaneous maximized application of 3 orthogonal gradient systems as opposed to sequential acquisition in 3 directions in conventional 3-scan trace DWI (tDWI). Several theoretical advantages of dDWI v...

  • Article
  • Open Access
1 Citations
1,897 Views
10 Pages

Assessing the Agreement Between Diffusion Tension Imaging (DTI) and T2-Weighted MRI Sequence for Biometry of the Fetal Corpus Callosum

  • Liel N. Cohn,
  • Shai Bookstein,
  • Tamar Laytman Klein,
  • Nadia Mordenfeld Kozlovsky,
  • Tomer Ziv-Baran,
  • Arnaldo Mayer and
  • Eldad Katorza

29 November 2024

Background/Objectives: Little is known about the advantages of Diffusion Tensor Imaging (DTI) when evaluating the fetal corpus callosum (CC), a sensitive indicator for normal brain development. This study evaluates the contribution of DTI compared to...

  • Article
  • Open Access
16 Citations
4,111 Views
16 Pages

Restricted Water Diffusion in Diffusion-Weighted Magnetic Resonance Imaging in Pancreatic Cancer is Associated with Tumor Hypoxia

  • Philipp Mayer,
  • Anne Kraft,
  • Hagen R. Witzel,
  • Nicole Marnet,
  • Nina Hörner,
  • Wilfried Roth,
  • Stefan Heinrich,
  • Thilo Hackert,
  • Frank Bergmann and
  • Matthias M. Gaida
  • + 2 authors

30 December 2020

Hypoxia is a hallmark of pancreatic cancer (PDAC) due to its compact and extensive fibrotic tumor stroma. Hypoxia contributes to high lethality of this disease, by inducing a more malignant phenotype and resistance to radiation and chemotherapy. Thus...

  • Article
  • Open Access
10 Citations
3,098 Views
11 Pages

Diffusion Weighted Imaging in the Assessment of Tumor Grade in Endometrial Cancer Based on Intravoxel Incoherent Motion MRI

  • Evangelia G. Chryssou,
  • Georgios C. Manikis,
  • Georgios S. Ioannidis,
  • Vrettos Chaniotis,
  • Thomas Vrekoussis,
  • Thomas G. Maris,
  • Kostas Marias and
  • Apostolos H. Karantanas

The aim of this study is to investigate the possibility of predicting histological grade in patients with endometrial cancer on the basis of intravoxel incoherent motion (IVIM)-related histogram analysis parameters. This prospective study included 52...

  • Article
  • Open Access
6 Citations
2,926 Views
12 Pages

Amide Proton Transfer-Weighted Imaging Combined with ZOOMit Diffusion Kurtosis Imaging in Predicting Lymph Node Metastasis of Cervical Cancer

  • Qiuhan Huang,
  • Yanchun Wang,
  • Xiaoyan Meng,
  • Jiali Li,
  • Yaqi Shen,
  • Xuemei Hu,
  • Cui Feng,
  • Zhen Li and
  • Ihab Kamel

Background: The aim of this study is to investigate the feasibility of amide proton transfer-weighted (APTw) imaging combined with ZOOMit diffusion kurtosis imaging (DKI) in predicting lymph node metastasis (LNM) in cervical cancer (CC). Materials an...

  • Article
  • Open Access
1 Citations
2,977 Views
15 Pages

Pediatric Versus Adult Nasopharyngeal Cancer in Diffusion-Weighted Magnetic Resonance Imaging

  • Emil Crasnean,
  • Ruben Emanuel Nechifor,
  • Liviu Fodor,
  • Oana Almășan,
  • Nico Sollmann,
  • Alina Ban,
  • Raluca Roman,
  • Ileana Mitre,
  • Simion Bran and
  • Mihaela Hedeșiu
  • + 3 authors

3 July 2025

Background: This study aimed at evaluating apparent diffusion coefficient (ADC) values of nasopharyngeal carcinoma (NPC) in the pre-treatment stages of NPC for establishing comparative quantitative parameters between children and adolescents compared...

  • Article
  • Open Access
710 Views
11 Pages

15 August 2025

Apparent diffusion coefficient (ADC) values, derived from diffusion-weighted magnetic resonance imaging (DW-MRI), increase with age, reflecting microstructural changes in white matter integrity. However, factors beyond chronological aging may influen...

  • Review
  • Open Access
25 Citations
10,944 Views
18 Pages

30 November 2015

Reliable response criteria are critical for the evaluation of therapeutic response in hepatocellular carcinoma (HCC). Current response assessment is mainly based on: (1) changes in size, which is at times unreliable and lag behind the result of thera...

  • Article
  • Open Access
12 Citations
3,432 Views
12 Pages

Relationships and Qualitative Evaluation between Diffusion-Weighted Imaging and Pathologic Findings of Resected Lung Cancers

  • Katsuo Usuda,
  • Shun Iwai,
  • Aika Yamagata,
  • Atsushi Sekimura,
  • Nozomu Motono,
  • Munetaka Matoba,
  • Mariko Doai,
  • Sohsuke Yamada,
  • Yoshimichi Ueda and
  • Hidetaka Uramoto
  • + 1 author

8 May 2020

For detecting malignant tumors, diffusion-weighted magnetic resonance imaging (DWI) as well as fluoro-2-deoxy-glucose positron emission tomography/computed tomography (FDG-PET/CT) are available. It is not definitive how DWI correlates the pathologica...

  • Article
  • Open Access
1,069 Views
17 Pages

Evaluation of the Effect of X-Ray Therapy on Glioma Rat Model Using Chemical Exchange Saturation Transfer and Diffusion-Weighted Imaging

  • Kazuki Onishi,
  • Koji Itagaki,
  • Sachie Kusaka,
  • Tensei Nakano,
  • Junpei Ueda and
  • Shigeyoshi Saito

5 August 2025

Background/Objectives: This study aimed to examine the changes in brain metabolites and water molecule diffusion using chemical exchange saturation transfer (CEST) imaging and diffusion-weighted imaging (DWI) after 15 Gy of X-ray irradiation in a rat...

  • Article
  • Open Access
11 Citations
2,799 Views
13 Pages

High-Resolution, High b-Value Computed Diffusion-Weighted Imaging Improves Detection of Pancreatic Ductal Adenocarcinoma

  • Felix N. Harder,
  • Eva Jung,
  • Sean McTavish,
  • Anh Tu Van,
  • Kilian Weiss,
  • Sebastian Ziegelmayer,
  • Joshua Gawlitza,
  • Philip Gouder,
  • Omar Kamal and
  • Rickmer F. Braren
  • + 3 authors

18 January 2022

Background: Our purpose was to investigate the potential of high-resolution, high b-value computed DWI (cDWI) in pancreatic ductal adenocarcinoma (PDAC) detection. Materials and Methods: We retrospectively enrolled 44 patients with confirmed PDAC. Re...

  • Article
  • Open Access
2,006 Views
15 Pages

Diffusion weighted magnetic resonance imaging (DW-MRI) technique probing the microscopic movement of water molecules in tissue, allows for the quantification of water diffusivity and the contribution of perfusion to the total amount of water. In the...

  • Article
  • Open Access
6 Citations
2,282 Views
11 Pages

Tissue Characteristics of Endometrial Carcinoma Analyzed by Quantitative Synthetic MRI and Diffusion-Weighted Imaging

  • Yiang Wang,
  • Mengge He,
  • Peng Cao,
  • Philip P. C. Ip,
  • Chien-Yuan Lin,
  • Weiyin Liu,
  • Chia-Wei Lee and
  • Elaine Y. P. Lee

25 November 2022

Background: This study investigates the association of T1, T2, proton density (PD) and the apparent diffusion coefficient (ADC) with histopathologic features of endometrial carcinoma (EC). Methods: One hundred and nine EC patients were prospectively...

  • Article
  • Open Access
2,146 Views
17 Pages

Ensemble Learning for Breast Cancer Lesion Classification: A Pilot Validation Using Correlated Spectroscopic Imaging and Diffusion-Weighted Imaging

  • Ajin Joy,
  • Marlene Lin,
  • Melissa Joines,
  • Andres Saucedo,
  • Stephanie Lee-Felker,
  • Jennifer Baker,
  • Aichi Chien,
  • Uzay Emir,
  • Paul M. Macey and
  • M. Albert Thomas

The main objective of this work was to evaluate the application of individual and ensemble machine learning models to classify malignant and benign breast masses using features from two-dimensional (2D) correlated spectroscopy spectra extracted from...

  • Article
  • Open Access
1 Citations
2,559 Views
14 Pages

Magnetic Resonance with Diffusion and Dynamic Perfusion-Weighted Imaging in the Assessment of Early Chemoradiotherapy Response of Naso-Oropharyngeal Carcinoma

  • Michele Pietragalla,
  • Eleonora Bicci,
  • Linda Calistri,
  • Chiara Lorini,
  • Pierluigi Bonomo,
  • Andrea Borghesi,
  • Antonio Lo Casto,
  • Francesco Mungai,
  • Luigi Bonasera and
  • Cosimo Nardi
  • + 1 author

22 February 2023

The purpose of this study was to differentiate post-chemoradiotherapy (CRT) changes from tumor persistence/recurrence in early follow-up of naso-oropharyngeal carcinoma on magnetic resonance (MRI) with diffusion (DWI) and dynamic contrast-enhanced pe...

  • Article
  • Open Access
9 Citations
7,645 Views
17 Pages

Differentiated Epithelial- and Mesenchymal-Like Phenotypes in Subcutaneous Mouse Xenografts Using Diffusion Weighted-Magnetic Resonance Imaging

  • Ya-Wen Chen,
  • Huay-Ben Pan,
  • Hui-Hwa Tseng,
  • Hsiao-Chien Chu,
  • Yu-Ting Hung,
  • Yi-Chen Yen and
  • Chen-Pin Chou

5 November 2013

Epithelial-mesenchymal transition (EMT) is important for tumor metastasis. Detection of EMT protein expression and observation of morphological changes are commonly used to identify EMT. Diffusion-weighted magnetic resonance imaging (DW-MRI) and meas...

  • Article
  • Open Access
7 Citations
1,676 Views
10 Pages

Quantitative Non-Gaussian Intravoxel Incoherent Motion Diffusion-Weighted Imaging Metrics and Surgical Pathology for Stratifying Tumor Aggressiveness in Papillary Thyroid Carcinomas

  • David Aramburu Núñez,
  • Yonggang Lu,
  • Ramesh Paudyal,
  • Vaios Hatzoglou,
  • Andre L. Moreira,
  • Jung Hun Oh,
  • Hilda E. Stambuk,
  • Yousef Mazaheri,
  • Mithat Gonen and
  • Amita Shukla-Dave
  • + 3 authors

We assessed a priori aggressive features using quantitative diffusion-weighted imaging metrics to preclude an active surveillance management approach in patients with papillary thyroid cancer (PTC) with tumor size 1–2 cm. This prospective study enrol...

  • Article
  • Open Access
990 Views
19 Pages

Association of Intracellular Microstructural and Neuropsychological Changes in HIV: A Pilot Validation of Trace Diffusion-Weighted Magnetic Resonance Spectroscopic Imaging Using Radial Trajectories

  • Ajin Joy,
  • Andres Saucedo,
  • Matthew J. Wright,
  • Pranathi Vallabhu,
  • Neha Gupta,
  • James Sayre,
  • Aichi Chien,
  • Uzay Emir,
  • Paul M. Macey and
  • M. Albert Thomas
  • + 1 author

13 October 2025

Background: Despite effective antiretroviral therapy, HIV-associated neurocognitive disorders (HANDs) remain prevalent, highlighting the need for sensitive biomarkers of early brain alterations. Trace-weighted diffusion spectroscopic imaging offers a...

  • Article
  • Open Access
4 Citations
2,746 Views
11 Pages

Predict Treatment Response by Magnetic Resonance Diffusion Weighted Imaging: A Preliminary Study on 46 Meningiomas Treated with Proton-Therapy

  • Paola Feraco,
  • Daniele Scartoni,
  • Giulia Porretti,
  • Riccardo Pertile,
  • Davide Donner,
  • Lorena Picori and
  • Dante Amelio

15 September 2021

Objective: a considerable subgroup of meningiomas (MN) exhibit indolent and insidious growth. Strategies to detect earlier treatment responses based on tumour biology rather than on size can be useful. We aimed to characterize therapy-induced changes...

  • Article
  • Open Access
5 Citations
3,364 Views
11 Pages

Magnetic Resonance Imaging of Peritoneal Carcinomatosis: Evaluation of High b-Value Computed Diffusion-Weighted Imaging

  • Maxime Ablefoni,
  • Jakob Leonhardi,
  • Constantin Ehrengut,
  • Matthias Mehdorn,
  • Robert Sucher,
  • Ines Gockel,
  • Timm Denecke and
  • Hans-Jonas Meyer

29 June 2022

Over the last few years, diffusion-weighted imaging (DWI) has become increasingly relevant in the diagnostic assessment of peritoneal carcinomatosis. The aim of this study was to investigate the benefits of high-b DWI (c-DWI) compared to standard DWI...

  • Communication
  • Open Access
3 Citations
6,630 Views
10 Pages

31 December 2021

Rokitansky-Aschoff sinuses (RAS) are a common imaging finding in gallbladder adenomyomatosis (ADM), often presenting as fundal cystic spaces. Intracholecystic papillary neoplasm (ICPN) is a relatively uncommon pre-invasive tumor of the gallbladder ep...

  • Article
  • Open Access
1 Citations
1,699 Views
11 Pages

Diffusion-Weighted Magnetic Resonance Imaging for the Diagnosis of Lymph Node Metastasis in Patients with Biliary Tract Cancer

  • Takashi Murakami,
  • Hiroaki Shimizu,
  • Hiroyuki Nojima,
  • Kiyohiko Shuto,
  • Akihiro Usui,
  • Chihiro Kosugi and
  • Keiji Koda

13 September 2024

Objective: The diagnostic efficacy of the apparent diffusion coefficient (ADC) in diffusion-weighted magnetic resonance imaging (DW-MRI) for lymph node metastasis in biliary tract cancer was investigated in the present study. Methods: In total, 112 s...

  • Article
  • Open Access
10 Citations
3,231 Views
13 Pages

Diffusion-Weighted Imaging and Mapping of T1 and T2 Relaxation Time for Evaluation of Chronic Renal Allograft Rejection in a Translational Mouse Model

  • Martina Schmidbauer,
  • Song Rong,
  • Marcel Gutberlet,
  • Rongjun Chen,
  • Jan Hinrich Bräsen,
  • Dagmar Hartung,
  • Martin Meier,
  • Frank Wacker,
  • Hermann Haller and
  • Katja Derlin
  • + 2 authors

23 September 2021

We hypothesized that multiparametric MRI is able to non-invasively assess, characterize and monitor renal allograft pathology in a translational mouse model of chronic allograft rejection. Chronic rejection was induced by allogenic kidney transplanta...

  • Article
  • Open Access
12 Citations
2,903 Views
14 Pages

Texture Analysis of Multi-Shot Echo-Planar Diffusion-Weighted Imaging in Head and Neck Squamous Cell Carcinoma: The Diagnostic Value for Nodal Metastasis

  • Jung Hyun Park,
  • Yun Jung Bae,
  • Byung Se Choi,
  • Young Ho Jung,
  • Woo-Jin Jeong,
  • Hyojin Kim,
  • Leonard Sunwoo,
  • Cheolkyu Jung and
  • Jae Hyoung Kim

23 October 2019

Accurate assessment of nodal metastasis in head and neck squamous cell carcinoma (SCC) is important, and diffusion-weighted imaging (DWI) has emerged as a potential technique in differentiating benign from malignant lymph nodes (LNs). This study aims...

  • Article
  • Open Access
1 Citations
2,432 Views
16 Pages

Background: Diffusion-weighted imaging (DWI), a pivotal component of multiparametric magnetic resonance imaging (mpMRI), plays a pivotal role in the detection, diagnosis, and evaluation of gastric cancer. Despite its potential, DWI is often marred by...

  • Article
  • Open Access
14 Citations
3,759 Views
12 Pages

Diagnostic Benefit of High b-Value Computed Diffusion-Weighted Imaging in Patients with Hepatic Metastasis

  • Maxime Ablefoni,
  • Hans Surup,
  • Constantin Ehrengut,
  • Aaron Schindler,
  • Daniel Seehofer,
  • Timm Denecke and
  • Hans-Jonas Meyer

14 November 2021

Diffusion-weighted imaging (DWI) has rapidly become an essential tool for the detection of malignant liver lesions. The aim of this study was to investigate the usefulness of high b-value computed DWI (c-DWI) in comparison to standard DWI in patients...

  • Case Report
  • Open Access
1 Citations
1,938 Views
10 Pages

24 May 2024

Background: Progressive auditory dysfunction is common in patients with generalized neurodegenerative conditions, but clinicians currently lack the diagnostic tools to determine the location/degree of the pathology and, hence, to provide appropriate...

  • Article
  • Open Access
2 Citations
2,326 Views
12 Pages

Usefulness of Diffusion-Weighted Imaging in Evaluating Acute Cellular Rejection and Monitoring Treatment Response in Liver Transplant Recipients

  • Hsien-Jen Chiang,
  • Yi-Hsuan Chuang,
  • Chun-Wei Li,
  • Chih-Che Lin,
  • Hock-Liew Eng,
  • Chao-Long Chen,
  • Yu-Fan Cheng and
  • Ming-Chung Chou

Acute cellular rejection (ACR) is a significant immune issue among recipients following liver transplantation. Although diffusion-weighted magnetic resonance imaging (DWI) is widely used for diagnosing liver disease, it has not yet been utilized for...

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