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1,695 Results Found

  • Article
  • Open Access
16 Citations
8,308 Views
17 Pages

Decision-making is a central skill of basketball players intending to excel individually and contribute to their teams’ success. The assessment of such skills is particularly challenging in complex team sports. To address this challenge, this study a...

  • Brief Report
  • Open Access
4 Citations
2,424 Views
12 Pages

When making decisions under uncertainty, people in all walks of life, including highly trained medical professionals, tend to resort to using ‘mental shortcuts’, or heuristics. Anchoring-and-adjustment (AAA) is a well-known heuristic in w...

  • Review
  • Open Access
1 Citations
2,091 Views
11 Pages

Novel Advances in Qualitative Diagnostic Imaging for Decision Making in Multidisciplinary Treatment for Advanced Esophageal Cancer

  • Shinichi Okazumi,
  • Gaku Ohira,
  • Koichi Hayano,
  • Tomoyoshi Aoyagi,
  • Shunsuke Imanishi and
  • Hisahiro Matsubara

22 January 2024

Background: Recently, neoadjuvant therapy and the succeeding surgery for advanced esophageal cancer have been evaluated. In particular, the response to the therapy has been found to affect surgical outcomes, and thus a precise evaluation of treatment...

  • Article
  • Open Access
1 Citations
2,328 Views
19 Pages

In diagnostic accuracy studies, the test of interest is typically applied only once in each patient. This paper illustrates some possibilities that arise when diagnoses are carried out by a sufficiently large number of multiple raters. In a dental st...

  • Systematic Review
  • Open Access
1,712 Views
12 Pages

12 November 2025

Objectives: This study aimed to systematically compare the diagnostic accuracy of magnetic resonance imaging (MRI) and transvaginal ultrasound (TVUS) for deep infiltrating endometriosis (DIE) and to evaluate their impact on surgical decision-making....

  • Opinion
  • Open Access
2 Citations
3,356 Views
7 Pages

13 September 2024

Modern healthcare systems are increasingly organized according to diagnosis-specific clinical pathways and treatment protocols. At the same time, the number of patients with complex problems and needs that do not fit the single-diagnosis approach is...

  • Review
  • Open Access
9 Citations
4,728 Views
17 Pages

16 December 2023

Decision making consists of gathering quality data in order to correctly assess a situation and determine the best course of action. This process is a fundamental part of medicine and is what enables practitioners to accurately diagnose diseases and...

  • Protocol
  • Open Access
1,399 Views
16 Pages

A Clinical Probability-Based, Stepwise Algorithm for the Diagnosis of Giant Cell Arteritis: Study Protocol and Baseline Characteristics of the First 50 Patients Included in the Prospective Validation Study with Focus on Cranial Symptoms

  • Lukas-Caspar Thielmann,
  • Melike Findik-Kilinc,
  • Louise Füeßl,
  • Christian Lottspeich,
  • Anja Löw,
  • Teresa Henke,
  • Sandra Hasmann,
  • Ilaria Prearo,
  • Amanda von Bismarck and
  • Michael Czihal
  • + 10 authors

26 March 2025

Background: Early diagnosis of giant cell arteritis (GCA) is crucial to avoid loss of vision, but detailed headache characteristics of GCA have been poorly studied. Clinical prediction rules have shown promise in guiding management decisions in suspe...

  • Article
  • Open Access
3,754 Views
13 Pages

From Diagnosis to Satisfaction in Multiple Sclerosis: A Swiss Patient Survey Highlighting the Importance of the First Diagnostic Consultation

  • Christian P. Kamm,
  • Praveen Manjakunnel,
  • Dirk Lehnick,
  • Martin Welter,
  • Andrew Chan,
  • Nicole Kamber and
  • Tim Vanbellingen

Background: An early treatment start with disease modifying therapies (DMT) and long-term adherence is crucial in the treatment of people with multiple sclerosis (PwMS) to prevent future disability. Objectives: To gain information on the diagnostic p...

  • Article
  • Open Access
8 Citations
3,707 Views
14 Pages

Diagnosis of DSD in Children—Development of New Tools for a Structured Diagnostic and Information Management Program within the Empower-DSD Study

  • Katja Wechsung,
  • Louise Marshall,
  • Martina Jürgensen,
  • Uta Neumann and
  • on behalf of the Empower-DSD Study Group

3 July 2022

Background: Current recommendations define a structured diagnostic process, transparent information, and psychosocial support by a specialized, multi-professional team as central in the care for children and adolescents with genital variations and a...

  • Article
  • Open Access
464 Views
14 Pages

How Well Does ChatGPT-4o Reason? Expert Evaluation of Diagnostic and Therapeutic Performance in Hand Surgery

  • Léna G. Dietrich,
  • Laura De Pellegrin,
  • Valeria Rinaldi,
  • Yves Harder,
  • Esther Vögelin and
  • Esin Rothenfluh

13 November 2025

Background: The application of large language model (LLM) in surgical decision-making is rapidly expanding, yet its potential in hand and peripheral nerve surgery remains largely unexplored. This study assessed the diagnostic and therapeutic performa...

  • Article
  • Open Access
1 Citations
3,092 Views
11 Pages

Evaluating the Diagnostic Accuracy of a Novel Bayesian Decision-Making Algorithm for Vision Loss

  • Amy Basilious,
  • Chris N. Govas,
  • Alexander M. Deans,
  • Pradeepa Yoganathan and
  • Robin M. Deans

4 April 2022

The current diagnostic aids for acute vision loss are static flowcharts that do not provide dynamic, stepwise workups. We tested the diagnostic accuracy of a novel dynamic Bayesian algorithm for acute vision loss. Seventy-nine “participants&rdq...

  • Article
  • Open Access
8 Citations
5,184 Views
13 Pages

Framing Effects on Decision-Making for Diagnostic Genetic Testing: Results from a Randomized Trial

  • Andrew A. Dwyer,
  • Hongjie Shen,
  • Ziwei Zeng,
  • Matt Gregas and
  • Min Zhao

20 June 2021

Genetic testing is increasingly part of routine clinical care. However, testing decisions may be characterized by regret as findings also implicate blood relatives. It is not known if genetic testing decisions are affected by the way information is p...

  • Perspective
  • Open Access
265 Views
18 Pages

Managing the Uncertainty of “Precision” While Navigating Goals of Care: A Framework for Collaborative Interpretation of Complex Genomic Testing Results in Critically-Ill Neonates

  • DonnaMaria E. Cortezzo,
  • Katharine Press Callahan,
  • Bimal P. Chaudhari,
  • Elliott M. Weiss,
  • Monica Hsiung Wojcik,
  • Krishna Acharya,
  • Amy B. Schlegel,
  • Kevin M. Sullivan and
  • Jessica T. Fry

26 December 2025

Each year, many neonates are born with genetic diagnoses that carry a range of prognoses. As the types and availability of genetic testing have expanded, neonatal intensive care units (NICUs) have served as “launching points” for their cl...

  • Review
  • Open Access
2 Citations
1,796 Views
25 Pages

5 August 2025

This literature review explores the role of symmetry in thermal sciences, fluid dynamics, and energy applications, emphasizing the theoretical and practical implications. Symmetry is a fundamental tool for simplifying complex problems, enhancing comp...

  • Feature Paper
  • Article
  • Open Access
2,597 Views
17 Pages

8 July 2025

Background: The effective use of electronic health records (EHRs) is an essential clinical skill, but medical schools have traditionally provided limited systematic teaching on the topic. Inefficient use of EHRs results in delays in diagnosis, fragme...

  • Article
  • Open Access
6 Citations
4,814 Views
34 Pages

Most developed countries already have high-quality in vitro diagnostic (IVD) techniques for diseases, but developing countries often do not have access to these technologies and cannot afford them. Enabling firms to leverage external resources to opt...

  • Article
  • Open Access
17 Citations
3,494 Views
25 Pages

Enhancing Diagnostic Decision-Making: Ensemble Learning Techniques for Reliable Stress Level Classification

  • Raghav V. Anand,
  • Abdul Quadir Md,
  • Shabana Urooj,
  • Senthilkumar Mohan,
  • Mohamad A. Alawad and
  • Adittya C.

16 November 2023

An intense level of academic pressure causes students to experience stress, and if this stress is not addressed, it can cause adverse mental and physical effects. Since the pandemic situation, students have received more assignments and other tasks d...

  • Article
  • Open Access
1,452 Views
22 Pages

Determinants of Implementation of Antimicrobial Stewardship Interventions for Managing Community Adult Acute Respiratory Infections: Qualitative Analysis from the OPTIMAS-GP Study Co-Design Phase

  • Margaret Jordan,
  • Mary Burns,
  • Colin Cortie,
  • Janette Radford,
  • Christine Metusela,
  • Judy Mullan,
  • Simon Eckermann,
  • Fiona Williams,
  • Caitlin Keighley and
  • Andrew Bonney
  • + 3 authors

11 September 2025

Background/Objectives: Antimicrobial stewardship (AMS) interventions are critical to reducing inappropriate antibiotic prescribing for acute respiratory infections (ARIs) in primary care and mitigating antimicrobial resistance (AMR). While interventi...

  • Systematic Review
  • Open Access
13 Citations
3,938 Views
13 Pages

12 September 2023

Early detection and accurate prediction of the risk of early childhood caries (ECC) are essential for effective prevention and management. This systematic review aims to assess the performance and applicability of machine learning algorithms in ECC p...

  • Article
  • Open Access
2 Citations
2,883 Views
16 Pages

The research refers to the modeling of the meaningful and relatively stable visual-figurative and verbal-sign representation of real problems in medical diagnostics of the human organs and systems. The core results of the research are presented. Here...

  • Review
  • Open Access
19 Citations
10,998 Views
18 Pages

Understanding the Economic Value of Molecular Diagnostic Tests: Case Studies and Lessons Learned

  • Adrian Towse,
  • Diego Ossa,
  • David Veenstra,
  • Josh Carlson and
  • Louis Garrison

25 October 2013

Ten years after completion of the Human Genome Project, progress towards making “personalized medicine” a reality has been slower than expected. The reason is twofold. Firstly, the science is more difficult than expected. Secondly, limited progress h...

  • Article
  • Open Access
21 Citations
5,166 Views
17 Pages

Forecasting the Walking Assistance Rehabilitation Level of Stroke Patients Using Artificial Intelligence

  • Kanghyeon Seo,
  • Bokjin Chung,
  • Hamsa Priya Panchaseelan,
  • Taewoo Kim,
  • Hyejung Park,
  • Byungmo Oh,
  • Minho Chun,
  • Sunjae Won,
  • Donkyu Kim and
  • Jihoon Yang
  • + 2 authors

Cerebrovascular accidents (CVA) cause a range of impairments in coordination, such as a spectrum of walking impairments ranging from mild gait imbalance to complete loss of mobility. Patients with CVA need personalized approaches tailored to their de...

  • Review
  • Open Access

Toward Safer Diagnoses: A SEIPS-Based Narrative Review of Diagnostic Errors

  • Carol Yen,
  • John W. Epling,
  • Michelle Rockwell and
  • Monifa Vaughn-Cooke

Diagnostic errors have been a critical concern in healthcare, leading to substantial financial burdens and serious threats to patient safety. The Improving Diagnosis in Health Care report by the National Academies of Sciences, Engineering, and Medici...

  • Article
  • Open Access
12 Citations
5,177 Views
35 Pages

14 May 2025

In today’s high-stakes arenas—from healthcare to defense—algorithms are advancing at an unprecedented pace, yet they still lack a crucial element of human decision-making: an instinctive caution that helps prevent harm. Inspired by...

  • Article
  • Open Access
1 Citations
3,625 Views
13 Pages

Gadoxetic Acid-Based MRI for Decision-Making in Hepatocellular Carcinoma Employing Perfusion Criteria Only—A Post Hoc Analysis from the SORAMIC Trial Diagnostic Cohort

  • Max Seidensticker,
  • Ingo G. Steffen,
  • Irene Bargellini,
  • Thomas Berg,
  • Alberto Benito,
  • Bernhard Gebauer,
  • Roberto Iezzi,
  • Christian Loewe,
  • Musturay Karçaaltincaba and
  • Jens Ricke
  • + 5 authors

27 January 2022

The value of gadoxetic acid in the diagnosis of hepatocellular carcinoma (HCC), based on perfusion criteria, is under dispute. This post-hoc analysis of the prospective, phase II, randomized, controlled SORAMIC study compared the accuracy of gadoxeti...

  • Article
  • Open Access
13 Citations
3,770 Views
23 Pages

7 February 2023

Historical timber roofs play a significant role in architectural heritage, as listed in the World Heritage List protected by UNESCO. Despite their complexity, they are frequently lacking in maintenance, with the consequence that only a few original e...

  • Article
  • Open Access
1 Citations
2,370 Views
12 Pages

This study aimed to analyse clinical and laboratory findings in primary care patients with respiratory tract infections to distinguish the group more likely to receive antibiotic treatment. The study group consisted of 631 patients (264 males; 367 fe...

  • Review
  • Open Access
50 Citations
16,350 Views
31 Pages

19 September 2022

In recent decades, the increased use of sensor technologies, as well as the increase in digitalisation of aircraft sustainment and operations, have enabled capabilities to detect, diagnose, and predict the health of aircraft structures, systems, and...

  • Article
  • Open Access
1 Citations
1,776 Views
25 Pages

8 March 2023

The liver is one of the most common locations for incidental findings during abdominal CT scans. There are multiple types of disease that can arise within the liver and many of them are nodular. The ultimate goal of our research is to develop an expe...

  • Review
  • Open Access
426 Citations
89,410 Views
38 Pages

As healthcare systems around the world face challenges such as escalating costs, limited access, and growing demand for personalized care, artificial intelligence (AI) is emerging as a key force for transformation. This review is motivated by the urg...

  • Article
  • Open Access
1,006 Views
16 Pages

Introduction: Carpal Tunnel Syndrome (CTS) is a prevalent neuropathy requiring accurate, non-invasive diagnostics to minimize patient burden. This study evaluates the New Energy Vision (NEV) camera, an RGB-based multispectral imaging tool, to detect...

  • Feature Paper
  • Review
  • Open Access
3 Citations
2,812 Views
46 Pages

17 November 2025

Background/Objectives: Autoimmune rheumatic diseases (AIRDs) are complex, heterogeneous, and relapsing–remitting conditions in which early diagnosis, flare prediction, and individualized therapy remain major unmet needs. This review aims to syn...

  • Article
  • Open Access
13 Citations
9,040 Views
12 Pages

Health economics is a discipline of economics applied to health care. One method used in health economics is decision tree modelling, which extrapolates the cost and effectiveness of competing interventions over time. Such decision tree models are th...

  • Review
  • Open Access
13 Citations
24,168 Views
17 Pages

Pulmonary Embolism in Pregnancy: A Review for Clinical Practitioners

  • Agata Makowska,
  • Thomas Treumann,
  • Stefan Venturini and
  • Michael Christ

13 May 2024

Diagnostic and therapeutic decision-making in pregnancy with suspected pulmonary embolism (PE) is challenging. European and other international professional societies have proposed various recommendations that are ambiguous, probably due to the unava...

  • Systematic Review
  • Open Access
6 Citations
5,460 Views
12 Pages

18 January 2022

Introduction: The integration of clinical inspection and diagnostic imaging forms the basis for endodontic diagnosis, decision making, treatment planning, and outcome assessments. In recent years, CBCT imaging has become a common diagnostic tool in e...

  • Article
  • Open Access
36 Citations
5,907 Views
17 Pages

15 May 2019

Small veterinary practice is experiencing steady improvement in diagnostics and therapies which enable veterinarians to offer evermore advanced medical care for their patients. This focus group study of veterinarians (n = 32) examined the impact of t...

  • Case Report
  • Open Access
955 Views
9 Pages

16 June 2025

Background: Diagnostic delay and error represent pervasive problems in healthcare with grave implications for treatment and prognosis. Though characteristic of human cognition, cognitive biases commonly contribute to delays in the physician decision-...

  • Review
  • Open Access
1,282 Views
17 Pages

25 September 2025

While having or raising a child with a neurodivergence can be rewarding and life-enhancing, a diagnosis may trigger stress as people adapt to and navigate a new “assumptive world”. The purpose of this paper is to draw on the Attention Def...

  • Article
  • Open Access
7 Citations
4,390 Views
24 Pages

Screening and diagnostic tests are used to classify people with and without a disease. Diagnostic accuracy measures are used to evaluate the correctness of a classification in clinical research and practice. Although this depends on the uncertainty o...

  • Article
  • Open Access
10 Citations
4,381 Views
36 Pages

27 February 2021

Screening and diagnostic tests are applied for the classification of people into diseased and non-diseased populations. Although diagnostic accuracy measures are used to evaluate the correctness of classification in clinical research and practice, th...

  • Proceeding Paper
  • Open Access
950 Views
7 Pages

Data visualization has empowered analyzing, exploring, and communicating data effectively. It has been widely adopted across diverse disciplines. However, research indicates that data visualization in education is mainly favored in distance learning...

  • Review
  • Open Access
1 Citations
3,043 Views
12 Pages

Ethical Considerations in Fetal Cardiology

  • Stefani Samples,
  • Rupali Gandhi,
  • Joyce Woo and
  • Angira Patel

Fetal cardiology has evolved over the last 40 years and changed the timing of diagnosis and counseling of congenital heart disease, decision-making, planning for treatment at birth, and predicting future surgery from the postnatal to the prenatal per...

  • Article
  • Open Access
9 Citations
4,456 Views
14 Pages

PET/MRI in the Presurgical Evaluation of Patients with Epilepsy: A Concordance Analysis

  • Katalin Borbély,
  • Miklós Emri,
  • István Kenessey,
  • Márton Tóth,
  • Júlia Singer,
  • Péter Barsi,
  • Zsolt Vajda,
  • Endre Pál,
  • Zoltán Tóth and
  • Imre Repa
  • + 14 authors

The aim of our prospective study was to evaluate the clinical impact of hybrid [18F]-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging ([18F]-FDG PET/MRI) on the decision workflow of epileptic patients with discordant electro...

  • Editorial
  • Open Access
2 Citations
1,521 Views
3 Pages

18 November 2022

This editorial of the Special Issue “Prostate Cancer: Recent Advances in Diagnostics and Treatment Planning” aims to draw more attention to the broad and diverse field of prostate cancer (PCa) diagnosis and the utilization of different di...

  • Review
  • Open Access
21 Citations
5,007 Views
11 Pages

Sex Differences in Epidemiology, Morphology, Mechanisms, and Treatment of Mitral Valve Regurgitation

  • Gregorio Tersalvi,
  • Lorenzo Gaiero,
  • Michele Capriolo,
  • Yvonne Cristoforetti,
  • Stefano Salizzoni,
  • Gaetano Senatore,
  • Giovanni Pedrazzini and
  • Luigi Biasco

24 May 2023

Sex-related disparities have been recognized in incidence, pathological findings, pathophysiological mechanisms, and diagnostic pathways of non-rheumatic mitral regurgitation. Furthermore, access to treatments and outcomes for surgical and interventi...

  • Communication
  • Open Access
35 Citations
7,959 Views
8 Pages

Optimizing Clinical Decision Making with Decision Curve Analysis: Insights for Clinical Investigators

  • Daniele Piovani,
  • Rozeta Sokou,
  • Andreas G. Tsantes,
  • Alfonso Stefano Vitello and
  • Stefanos Bonovas

10 August 2023

A large number of prediction models are published with the objective of allowing personalized decision making for diagnostic or prognostic purposes. Conventional statistical measures of discrimination, calibration, or other measures of model performa...

  • Article
  • Open Access
8 Citations
5,936 Views
17 Pages

Digital Diagnostics: The Potential of Large Language Models in Recognizing Symptoms of Common Illnesses

  • Gaurav Kumar Gupta,
  • Aditi Singh,
  • Sijo Valayakkad Manikandan and
  • Abul Ehtesham

16 January 2025

This study aimed to evaluate the potential of Large Language Models (LLMs) in healthcare diagnostics, specifically their ability to analyze symptom-based prompts and provide accurate diagnoses. The study focused on models including GPT-4, GPT-4o, Gem...

  • Article
  • Open Access
5 Citations
3,074 Views
16 Pages

Analysis of Mathematical Methods of Integral Expert Evaluation for Predictive Diagnostics of Technical Systems Based on the Kemeny Median

  • Vadim Manusov,
  • Aysulu Kalanakova,
  • Javod Ahyoev,
  • Inga Zicmane,
  • Seepana Praveenkumar and
  • Murodbek Safaraliev

At present, diagnostics of the current technical condition of high-voltage power equipment in power systems have become more important. This allows the estimation of the real technical condition of power equipment more accurately with its removal int...

  • Review
  • Open Access
1 Citations
756 Views
9 Pages

Genetic testing is rapidly becoming standard practice in the care of critically ill newborns within NICUs. Numerous studies have demonstrated the utility of genetic testing, including changes in clinical care, improved diagnostic certainty, and cost...

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