Spherical structures of dielectric and magnetic materials are studied intensively in basic research and employed widely in applications. The polarization, (P for dielectric and M for magnetic materials), is the parent physical vector of all relevant...
The widespread use of cross-linked polyethylene (XLPE) as insulation in cables may be attributed to its outstanding mechanical and dielectric properties. In order to quantitatively evaluate the insulation status of XLPE after thermal ageing, an accel...
The potassium–chloride cotransporter KCC2 is the main extruder of Cl- in neurons. It plays a fundamental role in the activity of the inhibitory neurotransmitters (GABA and glycine) since low levels of KCC2 promote intracellular Cl- accumulation...
Cortical spreading depolarization (CSD) is the neuronal correlate of migraine aura and the reliable consequence of acute brain injury. The role of CSD in triggering headaches that follow migraine aura and brain injury remains to be uncertain. We exam...
Depending on the study of the master curve technique, a temperature correction model for the polarization current of transformer polymer (cellulose) insulation, considering the effects of both moisture content (mc%) and temperature is proposed. In th...
Recently, a laboratory setup for microwave-based characterization of powder samples at elevated temperatures and different gas atmospheres was presented. The setup is particularly interesting for operando investigations on typical materials for exhau...
We propose a new method for calculating the volume depolarization ratio of light backscattered by the atmosphere and a lidar system that employs an auxiliary telescope to detect the depolarized component. It takes into account the possible error in t...
The temperature of the transition to the polar state in ferroelectric composites, representing spherical ferroelectric inclusions embedded in a dielectric matrix, under a depolarizing field effect is investigated. This temperature is determined both...
A 1550 nm all-fiber dual-polarization coherent Doppler lidar (DPCDL) was constructed to measure the depolarization ratio of atmospheric aerosols. In lidar systems, the polarization state of the laser source is typically required to be that of linearl...
Nurr1 and brain-derived neurotrophic factor (BDNF) play major roles in cognition. Nurr1 regulates BDNF in midbrain dopaminergic neurons and cerebellar granule cells. Nurr1 and BDNF are also highly expressed in the cerebral cortex, a brain area import...
The aim of this study was to characterize the distribution of the thrombin receptor, protease activated receptor 1 (PAR1), in the neuroretina. Neuroretina samples of wild-type C57BL/6J and PAR1−/− mice were processed for indirect immunofl...
The Isothermal Relaxation Current (IRC) method, as a non-destructive condition evaluation method based on insulation dielectric response, has been applied in the maintenance of power cables. However, the relaxation current is usually conducted throug...
A novel method was proposed for the experimental investigation of wavefront distortion introduced to amplified radiation by pumped active elements in high-power laser amplifiers. The method is based on the simultaneous measurement of temperature dist...
Cortical spreading depression (CSD) is an electrophysiologic pathological state in which a wave of depolarization in the cerebral cortex is followed by the suppression of spontaneous neuronal activity. This transient spread of neuronal depolarization...
In this study, a hydroalcoholic chestnut shell extract was characterized and tested on six different human cell lines. Gallic, ellagic, and syringic acids were the most abundant non-condensed compounds in the chestnut extract, as determined by high p...
Local actions of stressors induce electrical signals (ESs), influencing photosynthetic processes and probably increasing tolerance to adverse factors in higher plants. However, the participation of well-known depolarization ESs (action potentials and...
Na1/2Bi1/2TiO3-based materials have gained considerable attention for their potential to exhibit giant strain, very-high ionic conductivity comparable to yttria stabilized zirconia or high mechanical quality factor for use in high power ultrasonics....
Excessive glutamate damages neuronal cells via the accumulation of intracellular reactive oxygen species (ROS), calcium ion (Ca2+) influx, depolarization of mitochondrial membrane potential, and apoptosis, which may result in the development of chron...
It has previously been reported that the RhoA/Rho-associated kinase (ROCK) pathway is involved in depolarization-induced contraction triggered by high [K+] stimulation in rat caudal arterial smooth muscle. Furthermore, we reported that activation of...
In high-voltage (HV) transmission and distribution systems, HV apparatuses are subjected to electrical, thermal, and mechanical stresses that deteriorate the insulation performance. The polarization and depolarization current (PDC) measurement is an...
In the marine environment, sea salt aerosol particles transition from cubic or rectangular shapes when dry to various non-spherical shapes like ellipsoids and cylinders under different humidities. The complex humidity conditions and particle morpholo...
Experience-dependent changes to neural circuitry are shaped by spatially-restricted activity-dependent mRNA translation. Although the complexity of mRNA translation in neuronal cells is widely appreciated, translational profiles associated with neuro...
Dysregulated activity of helicase eIF4A drives transformation to and maintenance of cancer cell phenotype by reprogramming cellular translation. Interleukin 24 (IL-24) is a tumor-suppressing protein, which has the ability to inhibit angiogenesis, sen...
Polarized synchrotron emission from the radio halos of diffuse intracluster medium (ICM) in galaxy clusters are yet to be observed. To investigate the expected polarization in the ICM, we use high resolution (1 kpc) magnetohydrodynamic simulations of...
Neutrophils provide rapid and efficient defense mechanisms against invading pathogens. Upon stimulation with proinflammatory mediators, including complement factors and bacterial peptides, neutrophils respond with changes in their membrane potential,...
Roxadustat (FG-4592), an analog of 2-oxoglutarate, is an orally-administered, heterocyclic small molecule known to be an inhibitor of hypoxia inducible factor (HIF) prolyl hydroxylase. However, none of the studies have thus far thoroughly investigate...
A polarimetric radar method to estimate mean shapes of ice hydrometeors was applied to several snowfall and ice cloud events observed by operational and research weather radars. The hydrometeor shape information is described in terms of their aspect...
With the help of electrochemical methods, including CV and EIS, the influence of methimazole, carbimazole, and the concentration of the supporting electrolyte on the kinetics and mechanism of zinc electroreduction on a mercury electrode was compared...
Brain ischemia induces slow voltage shifts in the cerebral cortex, including waves of spreading depolarization (SD) and negative ultraslow potentials (NUPs), which are considered as brain injury markers. However, different electrode materials and loc...
As key components of innate immunity, lung antimicrobial proteins play a critical role in warding off invading respiratory pathogens. Lung surfactant protein A (SP-A) exerts synergistic antimicrobial activity with the N-terminal segment of the SP-B p...
Compact, stable, high-power and high repetition rate picosecond laser systems are excellent sources for optical parametric chirped pulse amplification systems and laser satellite ranging systems. Compared with the traditional complex high-power ampli...
Mitochondria hold redox homeostasis and energy metabolism as a crucial factor during oocyte maturation, while the exposure of estrogenic mycotoxin zearalenone causes developmental incapacity in porcine oocyte. This study aimed to reveal a potential r...
We report on a millijoule-level fiber–solid hybrid hundred-picosecond laser system with a stable performance and compact structure. The laser system is based on a master oscillator power amplifier structure containing an all-fiber master oscill...
Pairing of splice sites across an intron or exon is the central point of intron or exon definition in pre-mRNA splicing with the latter mode proposed for most mammalian exons. However, transcriptome-wide pairing within endogenous transcripts has not...
Chemotherapy-induced senescence (CIS) contributes to tumor persistence and relapse. In this study, we investigated the senolytic activity of piceatannol (PCT) in 5-fluorouracil (5FU)-induced senescent colorectal cancer (CRC) cells. Senescence was est...
The up-regulated expression of the Ca2+-activated K+ channel KCa3.1 in inflammatory CD4+ T cells has been implicated in the pathogenesis of inflammatory bowel disease (IBD) through the enhanced production of inflammatory cytokines, such as interferon...
Various drugs can be associated with QT prolongation. A prolonged QT interval leads to an increased risk for the development of ventricular tachyarrhythmias, particularly polymorphic ventricular tachycardia (torsades de pointes). Polymorphic arrhythm...
In this paper, a three-component decomposition algorithm is proposed for processing compact polarimetric SAR images. By using the correspondence between the covariance matrix and the Stokes vector, three-component scattering models for CTLR and DCP m...
Long-distance electrical signals caused by the local action of stressors influence numerous physiological processes in plants including photosynthesis and increase their tolerance to the action of adverse factors. Depolarization electrical signals we...
For effective transmission of excitation in neuromuscular junctions, the postsynaptic response amplitude must exceed a critical level of depolarization to trigger action potential spreading along the muscle-fiber membrane. At the presynaptic level, t...
The potential of the plasma membrane (Δψ) regulates the electrochemical potential between the outer and inner sides of cell membranes. The opportunistic fungal pathogen, Candida albicans, regulates the membrane potential in response to envi...
Adversity is particularly pernicious in early life, increasing the likelihood of developing psychiatric disorders in adulthood. Juvenile and adult rats exposed to social isolation show differences in anxiety-like behaviors and significant changes in...
Cannabidiol (CBD) is a naturally occurring compound found in the Cannabis plant that is known for its potential therapeutic effects. However, its impact on membrane ionic currents remains a topic of debate. This study aimed to investigate how CBD mod...
Ultraviolet B (UVB) induces cell death by increasing free radical production, activating apoptotic cell death pathways and depolarizing mitochondrial membrane potential. Coenzyme Q10 (CoQ10), an essential cofactor in the mitochondrial electron transp...
Understanding how past factors influence ion channel kinetics is essential for understanding complex phenomena in cardiac electrophysiology, such as early afterdepolarizations (EADs), which are abnormal depolarizations during the action potential pla...
Hepcidin, a cysteine-rich antimicrobial peptide, has a highly conserved gene structure in teleosts, and it plays an essential role in host immune response against various pathogenic bacteria. Nonetheless, few studies on the antibacterial mechanism of...
An acousto-optic Q-switching Ho:YLF ring oscillator at 2066.33 nm with two anti-misalignment corner cube reflectors (CCRs) pumped by a 1940 nm thulium-doped fiber laser is demonstrated. The depolarization effect of the CCR is expressed in the form of...
Accurate description of the single scattering properties of atmospheric particles can be an essential factor influencing the remote sensing of atmospheric microphysics. In this paper, a database for the linearized single scattering properties of ice...
Natural products black cumin—Nigella sativa (N. sativa) and wild garlic—Allium ursinum (AU) are known for their potential role in reducing cardiovascular risk factors, including antracycline chemotherapy. Therefore, this study investigate...
Burmannic acid (BURA) is a new apocarotenoid bioactive compound derived from Indonesian cinnamon; however, its anticancer effect has rarely been investigated in oral cancer cells. In this investigation, the consequences of the antiproliferation of or...
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