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60 Results Found

  • Article
  • Open Access
8 Citations
3,517 Views
12 Pages

Optimization of the Equine-Sperm Freeze Test in Purebred Spanish Horses by Incorporating Colloidal Centrifugation

  • Luna Gutiérrez-Cepeda,
  • Francisco Crespo,
  • Juan Carlos Blazquez and
  • Consuelo Serres

22 January 2023

The Purebred Spanish Horse, according to our clinical experience, is characterized by having a high number of stallions that do not meet the international commercial recommendations for equine-sperm cryopreservation. This means that artificial insemi...

  • Article
  • Open Access
5 Citations
2,064 Views
16 Pages

Colloidal noble metal nanoparticle aggregates have demonstrated significant advantages in surface-enhanced Raman scattering (SERS) analysis, particularly for online detection, due to their excellent optical properties, spatial homogeneity, and fluidi...

  • Article
  • Open Access
20 Citations
5,806 Views
18 Pages

17 April 2021

Differential centrifugal sedimentation (DCS) is based on physical separation of nanoparticles in a centrifugal field prior to their analysis. It is suitable for resolving particle populations, which only slightly differ in size or density. Agglomerat...

  • Article
  • Open Access
3 Citations
2,946 Views
11 Pages

Effect of Process Conditions and Colloidal Properties of Cellulose Nanocrystals Suspensions on the Production of Hydrogel Beads

  • Nicola Ferrari,
  • Cecilia Ada Maestri,
  • Paolo Bettotti,
  • Mario Grassi,
  • Michela Abrami and
  • Marina Scarpa

27 April 2021

The influence of the physical, rheological, and process parameters on the cellulose nanocrystal (CNC) drops before and after external gelation in a CaCl2 solution was investigated. The dominant role of the CNC’s colloidal suspension properties, such...

  • Article
  • Open Access
1,737 Views
15 Pages

Innovative Approaches to Avoid Antibiotic Use in Equine Semen Cryopreservation: Advancing Sustainable Reproductive Technologies

  • Sonsoles Mercedes Zabala,
  • Consuelo Serres,
  • Natalia Montero,
  • Francisco Crespo,
  • Pedro Luis Lorenzo,
  • Verónica Pérez-Aguilera,
  • Agustín Oliet,
  • Virginia Hijón,
  • Santiago Moreno and
  • Luna Gutiérrez-Cepeda
  • + 1 author

9 May 2025

This study evaluated the impact of different processing techniques on microbial load and sperm quality in frozen–thawed equine semen to identify alternatives to reduce the preventive use of antibiotics. Semen was obtained and processed under ri...

  • Article
  • Open Access
1 Citations
2,855 Views
15 Pages

Strategies to Reduce the Use of Antibiotics in Fresh and Chilled Equine Semen

  • Sonsoles Mercedes Zabala,
  • Consuelo Serres,
  • Natalia Montero,
  • Francisco Crespo,
  • Pedro Luis Lorenzo,
  • Verónica Pérez-Aguilera,
  • Carmen Galán,
  • Mónica Domínguez-Gimbernat,
  • Agustín Oliet and
  • Luna Gutiérrez-Cepeda
  • + 2 authors

5 January 2024

The study assessed the impact of four equine semen processing techniques on sperm quality and microbial load immediately post-processing and after 48 h of refrigeration. The aim was to explore the potential reduction of prophylactic antibiotic usage...

  • Article
  • Open Access
28 Citations
7,183 Views
11 Pages

4 April 2019

Colloidal stability as well as physicochemical and rheological properties are among the critical determinants of the sensory quality of beverages. The present study investigated the effects of lecithin, xanthan gum, propylene glycol alginate, and the...

  • Article
  • Open Access
6 Citations
5,576 Views
12 Pages

Density Gradient Selection of Colloidal Silver Nanotriangles for Assembling Dye-Particle Plasmophores

  • Rui Oliveira-Silva,
  • Mariana Sousa-Jerónimo,
  • David Botequim,
  • Nuno J. O. Silva,
  • Duarte M. F. Prazeres and
  • Pedro M. R. Paulo

A simple method based on sucrose density gradient centrifugation is proposed here for the fractionation of colloidal silver nanotriangles. This method afforded particle fractions with surface plasmon resonances, spanning from red to infrared spectral...

  • Article
  • Open Access
3 Citations
2,377 Views
9 Pages

25 February 2021

In this paper, we propose a modified gravity method by introducing centrifugal force to promote the stacking of silica particles and the order of formed colloidal crystals. In this method, a monodispersed silica colloidal solution is filled into empt...

  • Article
  • Open Access
1 Citations
1,890 Views
10 Pages

Effect of Colloid Centrifugation and Cold Storage of Boar Semen at 4 °C on Bacterial Load and Sperm Quality

  • CongBang Ngo,
  • Jane M. Morrell,
  • Ingrid Hansson,
  • Padet Tummaruk and
  • Aleksandar Cojkic

Background/Objectives: Alternatives to antibiotics in semen extenders used for pig breeding are needed. Cold storage of boar semen is possible in certain extenders; however, bacteria can still survive. Colloid centrifugation can remove bacteria; ther...

  • Article
  • Open Access
2 Citations
2,655 Views
19 Pages

26 April 2024

Attapulgite (APT) is widely used in wastewater treatment due to its exceptional adsorption and colloidal properties, as well as its cost-effectiveness and eco-friendliness. However, low-grade APT generally limits its performance. Here, a colloid mill...

  • Review
  • Open Access
32 Citations
9,459 Views
27 Pages

27 January 2021

A centrifugal field can provide an external force for the ordering of nanoparticles. Especially with the knowledge from in-situ characterization by analytical (ultra)centrifugation, nanoparticle ordering can be rationally realized in preparative (ult...

  • Article
  • Open Access
16 Citations
4,189 Views
12 Pages

21 November 2021

Label-free SERS is a powerful bio-analytical technique in which molecular fingerprinting is combined with localized surface plasmons (LSPs) on metal surfaces to achieve high sensitivity. Silver and gold colloids are among the most common nanostructur...

  • Article
  • Open Access
6 Citations
2,718 Views
18 Pages

14 October 2022

The release of colloid-bound trace metals from abandoned coal mine spoils can potentially be a significant source of contamination during weathering. We examined the size-dependent enrichment of trace metals in mine spoil samples using centrifugation...

  • Feature Paper
  • Article
  • Open Access
6 Citations
3,805 Views
12 Pages

22 April 2022

The interaction between Janus colloids and giant lipid vesicles was experimentally investigated to elucidate the dynamics and mechanisms related to microparticle engulfment by lipid vesicles. Janus (Pt–SiO2 and Pt–MF, where MF is melamine...

  • Article
  • Open Access
1 Citations
1,564 Views
17 Pages

Multiphase Partitioning of Estrogens in a River Impacted by Feedlot Wastewater Discharge

  • Kuo-Hui Yang,
  • Hao-Shen Hung,
  • Wei-Hsiang Huang,
  • Chi-Ying Hsieh and
  • Ting-Chien Chen

14 September 2024

Estrogens in river systems can significantly impact aquatic ecosystems. This study aimed to investigate the multiphase partitioning of estrogens in Wulo Creek, Taiwan, which receives animal feedlot wastewater, to understand their distribution and pot...

  • Review
  • Open Access
79 Citations
17,131 Views
13 Pages

Alternatives to Antibiotics in Semen Extenders: A Review

  • Jane M. Morrell and
  • Margareta Wallgren

15 December 2014

Antibiotics are added to semen extenders to be used for artificial insemination (AI) in livestock breeding to control bacterial contamination in semen arising during collection and processing. The antibiotics to be added and their concentrations for...

  • Article
  • Open Access
6 Citations
4,016 Views
22 Pages

30 November 2021

Five sample-preparation techniques were compared to quantify 31 elements in coal humic substances (HS) by ICP–AES from the viewpoints of complete isolation and speciation of elements. They include, for bulk composition, preparation of an aqueou...

  • Article
  • Open Access
1 Citations
2,240 Views
12 Pages

The optimization of fabrication conditions for colloidal micron-sized oblates obtained by the deformation of an oil-in-hydrogel emulsion is reported. The influence of the type of emulsion stabilizer, ultrasonication parameters, and emulsion and gel m...

  • Article
  • Open Access
5 Citations
2,250 Views
18 Pages

The Influence of Medium on Fluorescence Quenching of Colloidal Solutions of the Nd3+: LaF3 Nanoparticles Prepared with HTMW Treatment

  • Elena Timofeeva,
  • Elena Orlovskaya,
  • Alexandr Popov,
  • Artem Shaidulin,
  • Sergei Kuznetsov,
  • Alexandr Alexandrov,
  • Oleg Uvarov,
  • Yuri Vainer,
  • Gleb Silaev and
  • Yurii Orlovskii
  • + 3 authors

25 October 2022

An original method was proposed to reduce the quenching of the NIR fluorescence of colloidal solutions of 0.1 at. % Nd3+: LaF3 nanoparticles (NPs) synthesized by aqueous co-precipitation method followed by hydrothermal microwave treatment. For this,...

  • Article
  • Open Access
11 Citations
2,464 Views
14 Pages

Molecular and Nano-Structural Optimization of Nanoparticulate Mn2+-Hexarhenium Cluster Complexes for Optimal Balance of High T1- and T2-Weighted Contrast Ability with Low Hemoagglutination and Cytotoxicity

  • Bulat Salavatovich Akhmadeev,
  • Irek R. Nizameev,
  • Kirill V. Kholin,
  • Alexandra D. Voloshina,
  • Tatyana P. Gerasimova,
  • Aidar T. Gubaidullin,
  • Marsil K. Kadirov,
  • Ildus E. Ismaev,
  • Konstantin A. Brylev and
  • Asiya R. Mustafina
  • + 1 author

The present work introduces rational design of nanoparticulate Mn(II)-based contrast agents through both variation of the μ3 (inner) ligands within a series of hexarhenium cluster complexes [{Re63-Q)8}(CN)6]4 (Re6Q8, Q = S2−, Se2...

  • Article
  • Open Access
990 Views
23 Pages

Plasmonic Nanosensors for EGFR Detection: Optimizing Aptamer-Based Competitive Displacement Assays

  • Alexandra Falamas,
  • Andra-Sorina Tatar,
  • Sanda Boca and
  • Cosmin Farcău

15 October 2025

This study presents a comparative investigation of plasmonic sensing platforms based on colloidal gold nanoparticle (AuNP) suspensions and gold film over nanosphere (AuFoN) solid substrates for the detection of epidermal growth factor receptor (EGFR)...

  • Article
  • Open Access
45 Citations
6,792 Views
19 Pages

Albumin-Coated Single-Core Iron Oxide Nanoparticles for Enhanced Molecular Magnetic Imaging (MRI/MPI)

  • Abdulkader Baki,
  • Amani Remmo,
  • Norbert Löwa,
  • Frank Wiekhorst and
  • Regina Bleul

Colloidal stability of magnetic iron oxide nanoparticles (MNP) in physiological environments is crucial for their (bio)medical application. MNP are potential contrast agents for different imaging modalities such as magnetic resonance imaging (MRI) an...

  • Article
  • Open Access
1 Citations
1,223 Views
13 Pages

25 June 2025

Sperm quality is adversely affected by cryopreservation due to the increased production of reactive oxygen species, which affects the integrity of sperm membranes, motility, and DNA fragmentation. Three methods for removing seminal plasma, washing (c...

  • Article
  • Open Access
9 Citations
4,027 Views
13 Pages

13 March 2020

This paper studies a new convenient method to prepare microfibrillated cellulose from a bleached eucalyptus kraft pulp. First, the wood pulp was reacted with urea to produce cellulose carbamate (CC), and then the CC was treated with colloid mill in a...

  • Article
  • Open Access
9 Citations
5,050 Views
14 Pages

3 September 2020

In large-sized breweries, rough beer clarification is still carried out using Kieselguhr filters notwithstanding their environmental and safety implications. The main aim of this work was to test an innovative rough beer clarification and stabilizati...

  • Article
  • Open Access
5 Citations
2,672 Views
13 Pages

Optimization of Piezoresistive Strain Sensors Based on Gold Nanoparticle Deposits on PDMS Substrates for Highly Sensitive Human Pulse Sensing

  • Yu-Shun Su,
  • Wei-Rong Yang,
  • Wei-Wun Jheng,
  • Watson Kuo,
  • Shien-Der Tzeng,
  • Kiyokazu Yasuda and
  • Jenn-Ming Song

5 July 2022

In this study, highly-sensitive piezoresistive strain sensors based on gold nanoparticle thin films deposited on a stretchable PDMS substrate by centrifugation were developed to measure arterial pulse waveform. By controlling carbon chain length of s...

  • Article
  • Open Access
1 Citations
1,566 Views
26 Pages

The Incompatibility Pitfall in Refining Opportunity Crude Oils

  • Dicho Stratiev,
  • Ivelina Shishkova,
  • Georgi Georgiev,
  • Rosen Dinkov,
  • Angel Nedelchev,
  • Radoslava Nikolova,
  • Anife Veli,
  • Veselina Bureva,
  • Krassimir Atanassov and
  • Vesislava Toteva
  • + 2 authors

19 February 2025

Refining light and heavy oils in different proportions seems attractive, especially in cases of geopolitical, economic, environmental, and logistical constraints. The economical attractiveness could be undermined in cases where incompatibility occurs...

  • Article
  • Open Access
7 Citations
4,495 Views
14 Pages

Sperm Quality in Young Bull Semen Can Be Improved by Single Layer Centrifugation

  • Isabel Lima-Verde,
  • Emma Hurri,
  • Theodoros Ntallaris,
  • Anders Johannisson,
  • Hans Stålhammar and
  • Jane M. Morrell

15 September 2022

Interest in using semen from young bulls is increasing due to identifying promising animals by genomic selection. However, sperm quality in these ejaculates may not reach currently accepted standards for the cattle breeding industry. The purpose of t...

  • Article
  • Open Access
6 Citations
3,017 Views
14 Pages

Sensing the Anti-Epileptic Drug Perampanel with Paper-Based Spinning SERS Substrates

  • Andrea Macrelli,
  • Nicolò Simone Villa,
  • Andrea Lucotti,
  • David Dellasega,
  • Paolo Maria Ossi and
  • Matteo Tommasini

22 December 2021

The applications of SERS in therapeutic drug monitoring, or other fields of analytical chemistry, require the availability of sensitive sensors and experimental approaches that can be implemented in affordable ways. In this contribution, we show the...

  • Article
  • Open Access
23 Citations
5,457 Views
12 Pages

24 December 2021

Deltamethrin pesticides can cause inflammation, nephrotoxicity and hepatotoxicity as well as affect the activity of antioxidant enzymes in tissues. As a result of this concern, there is a rising focus on the development of fast and reliable pesticide...

  • Article
  • Open Access
4 Citations
2,622 Views
25 Pages

Application of Intercriteria and Regression Analyses and Artificial Neural Network to Investigate the Relation of Crude Oil Assay Data to Oil Compatibility

  • Ivelina Shiskova,
  • Dicho Stratiev,
  • Mariana Tavlieva,
  • Angel Nedelchev,
  • Rosen Dinkov,
  • Iliyan Kolev,
  • Frans van den Berg,
  • Simeon Ribagin,
  • Sotir Sotirov and
  • Krassimir Atanassov
  • + 3 authors

12 April 2024

The compatibility of constituents making up a petroleum fluid has been recognized as an important factor for trouble-free operations in the petroleum industry. The fouling of equipment and desalting efficiency deteriorations are the results of dealin...

  • Article
  • Open Access
8 Citations
3,939 Views
17 Pages

Research and Application of In Situ Sample-Processing Methods for Rapid Simultaneous Detection of Pyrethroid Pesticides in Vegetables

  • Bo Mei,
  • Weiyi Zhang,
  • Meilian Chen,
  • Xia Wang,
  • Min Wang,
  • Yinqing Ma,
  • Chunyan Zhu,
  • Bo Deng,
  • Hongkang Wang and
  • Dongsheng Feng
  • + 4 authors

A novel rapid and cost-effective pre-processing method for the simultaneous determination of pyrethroid pesticides in vegetables has been developed and validated. The process of pesticide extraction was carried out by the QuEChERS (quick, easy, cheap...

  • Article
  • Open Access
6 Citations
3,050 Views
17 Pages

Automated Quantum Dots Purification via Solid Phase Extraction

  • Malín G. Lüdicke,
  • Jana Hildebrandt,
  • Christoph Schindler,
  • Ralph A. Sperling and
  • Michael Maskos

9 June 2022

The separation of colloidal nanocrystals from their original synthesis medium is an essential process step towards their application, however, the costs on a preparative scale are still a constraint. A new combination of approaches for the purificati...

  • Article
  • Open Access
9 Citations
3,284 Views
33 Pages

9 December 2022

Colloidal behavior of kaolinite particles in water was investigated in this manuscript, without and with the addition of a polymer flocculant (non-anionic polyacrylamide (PAM)), using diverse imaging techniques in addition to LUMisizer. The addition...

  • Article
  • Open Access
9 Citations
3,822 Views
16 Pages

Activated Bentonite Nanocomposite for the Synthesis of Solketal from Glycerol in the Liquid Phase

  • Federico M. Perez,
  • Celeste Legarto,
  • María B. Lombardi,
  • Gerardo F. Santori,
  • Francisco Pompeo and
  • Nora N. Nichio

20 June 2022

Activated bentonites are low-cost acid catalysts used in several reactions. However, their application at an industrial scale is affected by the formation of colloidal suspensions when these bentonites are in aqueous solutions. In order to overcome t...

  • Article
  • Open Access
15 Citations
4,680 Views
15 Pages

Effect of the Chain Structure of Self-Emulsifying Polyester Sizing Agent on ILSS of Carbon Fiber/Unsaturated Polyester Resin Composites

  • Zhenyu Wang,
  • Huijun Guo,
  • Hang Zhou,
  • Xinfeng Ouyang,
  • Di Jiang,
  • Jianhua Li,
  • Qipeng Guo,
  • Jun Tang and
  • Chuncai Yang

19 September 2019

Herein, we report self-emulsifying anionic unsaturated polyester emulsions with different chain segments as novel sizing agents. The epoxy modified unsaturated polyester emulsions were synthesized via a self-emulsifying technique with no organic solv...

  • Article
  • Open Access
11 Citations
3,979 Views
19 Pages

22 April 2021

Liquid phase exfoliation (LPE) is widely used to produce colloidal dispersions of nanomaterials, in particular two-dimensional nanosheets. The degree of exfoliation, i.e., the length to thickness aspect ratio was shown to be intrinsically limited by...

  • Feature Paper
  • Article
  • Open Access
7 Citations
4,609 Views
18 Pages

Establishing SI-Traceability of Nanoparticle Size Values Measured with Line-Start Incremental Centrifugal Liquid Sedimentation

  • Vikram Kestens,
  • Victoria A. Coleman,
  • Jan Herrmann,
  • Caterina Minelli,
  • Alex G. Shard and
  • Gert Roebben

Line-start incremental centrifugal liquid sedimentation (disc-CLS) is a powerful technique to determine particle size based on the principles of Stokes’ law. As most input quantities of the Stokes equation cannot be easily determined for typica...

  • Article
  • Open Access
4 Citations
2,725 Views
16 Pages

8 September 2022

Accurate determination of the size and the number of nanoparticles plays an important role in many different environmental studies of nanomaterials, such as fate, toxicity, and occurrence in general. This work presents an accurate model that estimate...

  • Article
  • Open Access
9 Citations
6,058 Views
17 Pages

Acetic Acid-Modulated Room Temperature Synthesis of MIL-100 (Fe) Nanoparticles for Drug Delivery Applications

  • Mengli Ding,
  • Jingwen Qiu,
  • Stéphan Rouzière,
  • Christophe Rihouey,
  • Luc Picton and
  • Ruxandra Gref

16 January 2023

Due to their flexible composition, large surface areas, versatile surface properties, and degradability, nanoscale metal organic frameworks (nano MOFs) are drawing significant attention in nanomedicine. In particular, iron trimesate MIL-100 (Fe) is s...

  • Article
  • Open Access
2 Citations
2,596 Views
16 Pages

Simple Route to Increase Electrical Conductivity and Optical Transmittance in Graphene/Silver Nanoparticles Hybrid Suspensions

  • Egor A. Danilov,
  • Mikhail Veretennikov,
  • Maria Dronova,
  • Timofey Kalyakin,
  • Andrey A. Stepashkin,
  • Victor V. Tcherdyntsev and
  • Vladimir Samoilov

2 February 2023

Electrical and optical properties of graphene/silver nanoparticles hybrid suspensions intended for use in inkjet printing technologies were studied. Few-layered graphene particles were manufactured via a direct ultrasonic-assisted liquid-phase exfoli...

  • Article
  • Open Access
8 Citations
2,520 Views
14 Pages

Spray Flame Synthesis and Multiscale Characterization of Carbon Black–Silica Hetero-Aggregates

  • Simon Buchheiser,
  • Ferdinand Kistner,
  • Frank Rhein and
  • Hermann Nirschl

20 June 2023

The increasing demand for lithium-ion batteries requires constant improvements in the areas of production and recycling to reduce their environmental impact. In this context, this work presents a method for structuring carbon black aggregates by addi...

  • Article
  • Open Access
34 Citations
5,787 Views
16 Pages

Extraction of Carotenoids from Tomato Pomace via Water-Induced Hydrocolloidal Complexation

  • Jayesree Nagarajan,
  • Hang Pui Kay,
  • Nagendra Prasad Krishnamurthy,
  • Nagasundara Ramanan Ramakrishnan,
  • Turki M. S. Aldawoud,
  • Charis M. Galanakis and
  • Ooi Chien Wei

9 July 2020

Agro-industrial waste is a largely untapped natural resource of bioactive compounds including carotenoids and pectin. However, conventional solvent extraction involves the excessive use of organic solvents, costly equipment, and tedious operation. Th...

  • Article
  • Open Access
3 Citations
6,960 Views
15 Pages

1 July 2021

Sperm DNA fragmentation compromises fertilization and early embryo development. Since spermatozoa lack the machinery to repair DNA damage, to improve the likelihood of establishing a healthy pregnancy, it is preferable to process ejaculates of stalli...

  • Article
  • Open Access
7 Citations
4,585 Views
15 Pages

Facile Microwave Assisted Synthesis of Silver Nanostars for Ultrasensitive Detection of Biological Analytes by SERS

  • Radu Nicolae Revnic,
  • Gabriela Fabiola Știufiuc,
  • Valentin Toma,
  • Anca Onaciu,
  • Alin Moldovan,
  • Adrian Bogdan Țigu,
  • Eva Fischer-Fodor,
  • Romulus Tetean,
  • Emil Burzo and
  • Rareș Ionuț Știufiuc

We report a very simple, rapid and reproducible method for the fabrication of anisotropic silver nanostars (AgNS) that can be successfully used as highly efficient SERS substrates for different bioanalytes, even in the case of a near-infra-red (NIR)...

  • Article
  • Open Access
2 Citations
1,822 Views
18 Pages

Protocrystallinity of Monodispersed Ultra-Small Templated Mesoporous Silica Nanoparticles

  • Laurent Bonneviot,
  • Belén Albela,
  • Feifei Gao,
  • Pascal Perriat,
  • Thierry Epicier and
  • Mohamad El Eter

19 June 2024

Monodisperse and semi-faceted ultra-small templated mesoporous silica nanoparticles (US-MSNs) of 20–25 nm were synthesized using short-time hydrolysis of tetraethoxysilane (TEOS) at room temperature, followed by a dilution for nucleation quench...

  • Article
  • Open Access
11 Citations
2,799 Views
19 Pages

Adrenocortical carcinoma (ACC) is a heterogeneous malignancy related to poor prognosis and limited treatment options. The orphan drug mitotane (MT) is still a cornerstone in ACC therapy, however, its application is characterized by low aqueous solubi...

  • Article
  • Open Access
29 Citations
4,532 Views
19 Pages

Enhanced Corneal Penetration of a Poorly Permeable Drug Using Bioadhesive Multiple Microemulsion Technology

  • Mohamed Moustafa Ibrahim,
  • Doaa Nabih Maria,
  • XiangDi Wang,
  • Raven N. Simpson,
  • T.J. Hollingsworth and
  • Monica M. Jablonski

Corneal penetration is a key rate limiting step in the bioavailability of topical ophthalmic formulations that incorporate poorly permeable drugs. Recent advances have greatly aided the ocular delivery of such drugs using colloidal drug delivery syst...

  • Article
  • Open Access
5 Citations
3,983 Views
23 Pages

Catechol Containing Polyelectrolyte Complex Nanoparticles as Local Drug Delivery System for Bortezomib at Bone Substitute Materials

  • David Vehlow,
  • Jeremy P. H. Wong,
  • Birgit Urban,
  • Janek Weißpflog,
  • Annett Gebert,
  • Matthias Schumacher,
  • Michael Gelinsky,
  • Manfred Stamm and
  • Martin Müller

The proteasome inhibitor bortezomib (BZM) is one of the most potent anti-cancer drugs in the therapy of multiple myeloma. In this study, an adhesive drug delivery system (DDS) for BZM was developed. Therefore, we extended the present DDS concept of p...

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