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  • Article
  • Open Access
11 Citations
3,343 Views
14 Pages

Elicitor Activity of Low-Molecular-Weight Alginates Obtained by Oxidative Degradation of Alginates Extracted from Sargassum muticum and Cystoseira myriophylloides

  • Meriem Aitouguinane,
  • Zainab El Alaoui-Talibi,
  • Halima Rchid,
  • Imen Fendri,
  • Slim Abdelkafi,
  • Mohamed Didi Ould El-Hadj,
  • Zakaria Boual,
  • Didier Le Cerf,
  • Christophe Rihouey and
  • Cherkaoui El Modafar
  • + 5 authors

16 May 2023

Alginates extracted from two Moroccan brown seaweeds and their derivatives were investigated for their ability to induce phenolic metabolism in the roots and leaves of tomato seedlings. Sodium alginates (ALSM and ALCM) were extracted from the brown s...

  • Article
  • Open Access
7 Citations
4,776 Views
15 Pages

Characterization of Alginates of Sargassum from the Archipelago of Guadeloupe

  • Naika Marcin,
  • Valendy Thesnor,
  • Valentin Duvauchelle,
  • Alejandro Ponce-Mora,
  • Lucia Gimeno-Mallench,
  • Stacy Narayanin-Richenapin,
  • Laura Brelle,
  • Eloy Bejarano,
  • Christelle Yacou and
  • Gerardo Cebrian-Torrejon
  • + 4 authors

Sargassum is a genus of brown algae that causes a major impact to marine ecosystems. Although accumulation of this invasive seaweed is considered an environmental problem, Sargassum can also be resource of valuable molecules such as alginates. Algina...

  • Feature Paper
  • Review
  • Open Access
35 Citations
12,890 Views
21 Pages

Encapsulation in Alginates Hydrogels and Controlled Release: An Overview

  • Camille Colin,
  • Emma Akpo,
  • Aurélie Perrin,
  • David Cornu and
  • Julien Cambedouzou

This review aims to gather the current state of the art on the encapsulation methods using alginate as the main polymeric material in order to produce hydrogels ranging from the microscopic to macroscopic sizes. The use of alginates as an encapsulati...

  • Review
  • Open Access
511 Citations
26,684 Views
18 Pages

Structures, Properties and Applications of Alginates

  • Roya Abka-khajouei,
  • Latifa Tounsi,
  • Nasim Shahabi,
  • Anil Kumar Patel,
  • Slim Abdelkafi and
  • Philippe Michaud

29 May 2022

Alginate is a hydrocolloid from algae, specifically brown algae, which is a group that includes many of the seaweeds, like kelps and an extracellular polymer of some bacteria. Sodium alginate is one of the best-known members of the hydrogel group. Th...

  • Review
  • Open Access
120 Citations
15,239 Views
37 Pages

30 November 2021

Modified alginates have a wide range of applications, including in the manufacture of dressings and scaffolds used for regenerative medicine, in systems for selective drug delivery, and as hydrogel materials. This literature review discusses the meth...

  • Review
  • Open Access
56 Citations
8,635 Views
20 Pages

Structures, Properties, and Bioengineering Applications of Alginates and Hyaluronic Acid

  • Shuping Zhang,
  • Jiayu Dong,
  • Renxue Pan,
  • Zhenyang Xu,
  • Mengyuan Li and
  • Rui Zang

30 April 2023

In recent years, polymeric materials have been used in a wide range of applications in a variety of fields. In particular, in the field of bioengineering, the use of natural biomaterials offers a possible new avenue for the development of products wi...

  • Article
  • Open Access
6 Citations
4,487 Views
13 Pages

6 December 2023

Marine biomass has attracted attention as an environmentally sustainable energy source that can replace petroleum-based resources. Alginates, the main natural polysaccharides extracted from seaweeds, are used in various fields, such as food, pharmace...

  • Review
  • Open Access
63 Citations
10,695 Views
16 Pages

Heparin is widely recognized for its potent anticoagulating effects, but has an additional wide range of biological properties due to its high negative charge and heterogeneous molecular structure. This heterogeneity has been one of the factors in mo...

  • Article
  • Open Access
12 Citations
6,195 Views
10 Pages

Modification of pH Conferring Virucidal Activity on Dental Alginates

  • Navina Nallamuthu,
  • Michael Braden,
  • John Oxford,
  • David Williams and
  • Mangala Patel

21 April 2015

To formulate an alginate dental impression material with virucidal properties, experimental alginate dental impression materials were developed and the formulations adjusted in order to study the effect on pH profiles during setting. Commercially ava...

  • Article
  • Open Access
2 Citations
1,003 Views
12 Pages

Evaluation of Deformation and Antibacterial Properties of Dental Alginates Mixed with Silver Nanoparticles

  • Mario A. Rivera-Cortés,
  • Nereyda Niño-Martínez,
  • Facundo Ruiz,
  • Brianda Karina Félix-Sicairos and
  • Gabriel-Alejandro Martínez-Castañón

30 April 2025

This study aimed to evaluate the effect of the incorporation of silver nanoparticles (AgNPs) of 5.57 nm size into dental alginates on their deformation and antimicrobial properties. Six experimental groups were prepared: 2 different alginates with 0....

  • Article
  • Open Access
36 Citations
8,111 Views
17 Pages

Strontium- and Zinc-Containing Bioactive Glass and Alginates Scaffolds

  • Asfia Haider,
  • Ahmad Waseem,
  • Natalia Karpukhina and
  • Sahar Mohsin

With an increasingly elderly population, there is a proportionate increase in bone injuries requiring hospitalization. Clinicians are increasingly adopting tissue-engineering methods for treatment due to limitations in the use of autogenous and autol...

  • Article
  • Open Access
12 Citations
6,001 Views
16 Pages

6 December 2016

Understanding macrophage responses to biomaterials is crucial to the success of implanted medical devices, tissue engineering scaffolds, and drug delivery vehicles. Cellular responses to materials may depend synergistically on multiple surface chemis...

  • Article
  • Open Access
41 Citations
5,093 Views
12 Pages

Isolation and Structural Characterization of Alginates from the Kelp Species Laminaria ochroleuca and Saccorhiza polyschides from the Atlantic Coast of Morocco

  • Soukaina Kaidi,
  • Fouad Bentiss,
  • Charafeddine Jama,
  • Khaoula Khaya,
  • Zahira Belattmania,
  • Abdeltif Reani and
  • Brahim Sabour

Alginates are linear unbranched polysaccharides produced by brown seaweeds. The gel properties of this phycocolloid are mainly linked to the monomer composition, sequential structure and molecular weight of the polymeric chain. Nevertheless, these st...

  • Article
  • Open Access
115 Citations
8,764 Views
9 Pages

Isolation and FTIR-ATR and 1H NMR Characterization of Alginates from the Main Alginophyte Species of the Atlantic Coast of Morocco

  • Zahira Belattmania,
  • Soukaina Kaidi,
  • Samir El Atouani,
  • Chaimaa Katif,
  • Fouad Bentiss,
  • Charafeddine Jama,
  • Abdeltif Reani,
  • Brahim Sabour and
  • Vitor Vasconcelos

22 September 2020

Alginates are widely used as gelling agents in textile print pastes, medical industries, impression material in dentistry, and anticoagulant material in toothpaste. In the present study, the content and spectroscopic characterization (1H NMR and FT-I...

  • Article
  • Open Access
24 Citations
3,998 Views
20 Pages

Development of Sustainable, Mechanically Strong, and Self-Healing Bio-Thermoplastic Elastomers Reinforced with Alginates

  • Saul Utrera-Barrios,
  • Ornella Ricciardi,
  • Sergio González,
  • Raquel Verdejo,
  • Miguel Ángel López-Manchado and
  • Marianella Hernández Santana

30 October 2022

New bio-thermoplastic elastomer composites with self-healing capacities based on epoxidized natural rubber and polycaprolactone blends reinforced with alginates were developed. This group of salts act as natural reinforcing fillers, increasing the te...

  • Review
  • Open Access
46 Citations
6,573 Views
33 Pages

23 December 2022

Alginates (ALG) have been used in biomedical and pharmaceutical technologies for decades. ALG are natural polymers occurring in brown algae and feature multiple advantages, including biocompatibility, low toxicity and mucoadhesiveness. Moreover, ALG...

  • Article
  • Open Access
18 Citations
4,301 Views
16 Pages

Hydrogels Based on Alginates and Carboxymethyl Cellulose with Modulated Drug Release—An Experimental and Theoretical Study

  • Cătălina Anișoara Peptu,
  • Elena Simona Băcăiță,
  • Corina-Lenuta Savin (Logigan),
  • Marian Luțcanu and
  • Maricel Agop

20 December 2021

New hydrogels films crosslinked with epichlorohydrin were prepared based on alginates and carboxymethyl cellulose with properties that recommend them as potential drug delivery systems (e.g., biocompatibility, low toxicity, non-immunogenicity, hemost...

  • Article
  • Open Access
3 Citations
2,202 Views
14 Pages

26 November 2024

Alginate, a polysaccharide found in brown seaweeds, has regularly gained attention for its potential use as a source of bioactive compounds. However, it is structurally complex with a high molecular weight, limiting its application. Alginate oligosac...

  • Feature Paper
  • Article
  • Open Access
4 Citations
2,216 Views
25 Pages

Cascading One-Pot Synthesis of Biodegradable Uronic Acid-Based Surfactants from Oligoalginates, Semi-Refined Alginates, and Crude Brown Seaweeds

  • Freddy Pessel,
  • Guillaume Noirbent,
  • Cédric Boyère,
  • Sacha Pérocheau Arnaud,
  • Tiphaine Wong,
  • Laura Durand and
  • Thierry Benvegnu

The present article describes a one-pot and cascade mode process using biocompatible/biodegradable reagents, for simply obtaining surfactant compositions comprising mixtures of d-mannuronic acid and l-guluronic acid directly from oligoalginates or se...

  • Article
  • Open Access
40 Citations
5,809 Views
15 Pages

A Novel Alginate Lyase: Identification, Characterization, and Potential Application in Alginate Trisaccharide Preparation

  • Zhao Xue,
  • Xiao-Meng Sun,
  • Cui Chen,
  • Xi-Ying Zhang,
  • Xiu-Lan Chen,
  • Yu-Zhong Zhang,
  • Shou-Jin Fan and
  • Fei Xu

23 February 2022

Alginate oligosaccharides (AOS) have many biological activities and significant applications in prebiotics, nutritional supplements, and plant growth development. Alginate lyases have unique advantages in the preparation of AOS. However, only a limit...

  • Article
  • Open Access
14 Citations
3,770 Views
14 Pages

14 March 2023

The enzymatic degradation of seaweed polysaccharides is gaining interest for its potential in the production of functional oligosaccharides and fermentable sugars. Herein, a novel alginate lyase, AlyRm3, was cloned from a marine strain, Rhodothermus ...

  • Article
  • Open Access
89 Citations
11,965 Views
19 Pages

Viscoelastic Oxidized Alginates with Reversible Imine Type Crosslinks: Self-Healing, Injectable, and Bioprintable Hydrogels

  • Shahzad Hafeez,
  • Huey Wen Ooi,
  • Francis L. C. Morgan,
  • Carlos Mota,
  • Monica Dettin,
  • Clemens Van Blitterswijk,
  • Lorenzo Moroni and
  • Matthew B. Baker

21 November 2018

Bioprinting techniques allow for the recreation of 3D tissue-like structures. By deposition of hydrogels combined with cells (bioinks) in a spatially controlled way, one can create complex and multiscale structures. Despite this promise, the ability...

  • Review
  • Open Access
26 Citations
5,794 Views
15 Pages

24 December 2022

In this review, we aim to provide a summary of recent research advancements and applications of algin (i.e., alginic acid) and alginate-hybrid materials (AHMs) in medical fields. Algin/alginate are abundant natural products that are chemically inert...

  • Article
  • Open Access
15 Citations
3,856 Views
13 Pages

Characterization of a Novel Alginate Lyase with Two Alginate Lyase Domains from the Marine Bacterium Vibrio sp. C42

  • Xiao-Meng Sun,
  • Zhao Xue,
  • Mei-Ling Sun,
  • Yi Zhang,
  • Yu-Zhong Zhang,
  • Hui-Hui Fu,
  • Yu-Qiang Zhang and
  • Peng Wang

26 November 2022

Alginate is abundant in the cell walls of brown algae. Alginate lyases can degrade alginate, and thus play an important role in the marine carbon cycle and industrial production. Currently, most reported alginate lyases contain only one functional al...

  • Article
  • Open Access
921 Views
19 Pages

Genome Analysis of Alginate-Degrading Bacterium Vibrio sp. 32415 and Optimization of Alginate Lyase Production

  • Yi Zeng,
  • Jia Xu,
  • Zhongran Li,
  • Rujie Wei,
  • Haiyang Zhao,
  • Liqin Sun and
  • Chang Lu

Vibrio sp. is one of the main producers of alginate lyase; however, most strains have problems such as low and unstable enzyme production. In this study, the enzyme production conditions of V. sp. 32415, a marine bacterium capable of producing extrac...

  • Article
  • Open Access
9 Citations
3,553 Views
14 Pages

Polylactide-Grafted Metal-Alginate Aerogels

  • Grigorios Raptopoulos,
  • Ioannis Choinopoulos,
  • Filippos Kontoes-Georgoudakis and
  • Patrina Paraskevopoulou

21 March 2022

Τhis work describes the synthesis of PLA-grafted M-alginate (g-M-alginate; M: Ca2+, Co2+, Ni2+, Cu2+) aerogels. DL-lactide (LA) was attached on the surface of preformed M-alginate beads and was polymerized, using stannous octoate as catalyst and...

  • Article
  • Open Access
31 Citations
10,904 Views
15 Pages

Influence of Alginate Properties and Calcium Chloride Concentration on Alginate Bead Reticulation and Size: A Phenomenological Approach

  • Chanez Bennacef,
  • Stéphane Desobry,
  • Jordane Jasniewski,
  • Sébastien Leclerc,
  • Laurent Probst and
  • Sylvie Desobry-Banon

20 October 2023

Two types of alginates, AlgLF and AlgP, were used in this study to produce alginate beads by electro-vibratory extrusion. AlgLF and AlgP exhibited different Mannuronate/Guluronate (M/G) ratios and molecular weights as measured by NMR and SEC-MALS. Th...

  • Article
  • Open Access
8 Citations
2,819 Views
19 Pages

A Novel Cold-Adapted and High-Alkaline Alginate Lyase with Potential for Alginate Oligosaccharides Preparation

  • Hai-Ying Wang,
  • Zhi-Fang Chen,
  • Zhi-Hong Zheng,
  • Hui-Wen Lei,
  • Hai-Hua Cong and
  • Hai-Xiang Zhou

22 August 2023

Alginate oligosaccharides (AOs) prepared through enzymatic reaction by diverse alginate lyases under relatively controllable and moderate conditions possess versatile biological activities. But widely used commercial alginate lyases are still rather...

  • Article
  • Open Access
10 Citations
4,070 Views
14 Pages

1 October 2023

Mealworm-flour-formulated flour-based products have gained increasing attention; however, their textural properties need to be improved. Propylene glycol alginate (PGA) is a commercial food additive with excellent emulsifying and stabilizing capabili...

  • Article
  • Open Access
8 Citations
3,200 Views
18 Pages

Enhancing Soil Resilience: Bacterial Alginate Hydrogel vs. Algal Alginate in Mitigating Agricultural Challenges

  • Flavia Dorochesi,
  • Cesar Barrientos-Sanhueza,
  • Álvaro Díaz-Barrera and
  • Italo F. Cuneo

17 December 2023

Erosion and tillage changes negatively the soil physical structure, which directly impacts agricultural systems and consequently food security. To mitigate these adverse modifications, different polymeric materials from synthetic and natural sources,...

  • Article
  • Open Access
10 Citations
4,522 Views
14 Pages

4 March 2024

Alginate lyase (AL) is a polysaccharide-degrading enzyme that can degrade alginate by hydrolyzing glycosidic bonds and produces unsaturated alginate oligosaccharides (AOSs). These AOSs have wide therapeutic and nutraceutical applications. However, to...

  • Review
  • Open Access
67 Citations
7,309 Views
27 Pages

Alginate Lyases from Marine Bacteria: An Enzyme Ocean for Sustainable Future

  • Noora Barzkar,
  • Ruilong Sheng,
  • Muhammad Sohail,
  • Saeid Tamadoni Jahromi,
  • Olga Babich,
  • Stanislav Sukhikh and
  • Reza Nahavandi

The cell wall of brown algae contains alginate as a major constituent. This anionic polymer is a composite of β-d-mannuronate (M) and α-l-guluronate (G). Alginate can be degraded into oligosaccharides; both the polymer and its products exh...

  • Review
  • Open Access
230 Citations
13,928 Views
26 Pages

Advances in Research on the Bioactivity of Alginate Oligosaccharides

  • Maochen Xing,
  • Qi Cao,
  • Yu Wang,
  • Han Xiao,
  • Jiarui Zhao,
  • Qing Zhang,
  • Aiguo Ji and
  • Shuliang Song

28 February 2020

Alginate is a natural polysaccharide present in various marine brown seaweeds. Alginate oligosaccharide (AOS) is a degradation product of alginate, which has received increasing attention due to its low molecular weight and promising biological activ...

  • Article
  • Open Access
13 Citations
3,328 Views
16 Pages

Cloning and Characterization of a Novel Alginate Lyase from Paenibacillus sp. LJ-23

  • Mingpeng Wang,
  • Lei Chen,
  • Zhengyu Lou,
  • Xueting Yuan,
  • Guiping Pan,
  • Xiaoyan Ren and
  • Pengyu Wang

12 January 2022

As a low molecular weight alginate, alginate oligosaccharides (AOS) exhibit improved water solubility, better bioavailability, and comprehensive health benefits. In addition, their biocompatibility, biodegradability, non-toxicity, non-immunogenicity,...

  • Article
  • Open Access
5 Citations
2,581 Views
14 Pages

Direct Preparation of Alginate Oligosaccharides from Brown Algae by an Algae-Decomposing Alginate Lyase AlyP18 from the Marine Bacterium Pseudoalteromonas agarivorans A3

  • Xiao-Hui Sun,
  • Xiao-Dong Zhang,
  • Xin-Ru Zhang,
  • Xiao-Fei Wang,
  • Xi-Ying Zhang,
  • Yu-Zhong Zhang,
  • Yu-Qiang Zhang and
  • Fei Xu

26 October 2024

Alginate oligosaccharides (AOs), derived from alginate degradation, exhibit diverse biological activities and hold significant promise in various fields. The enzymatic preparation of AOs relies on alginate lyases, which offers distinct advantages. In...

  • Article
  • Open Access
7 Citations
2,686 Views
13 Pages

Preparation of Alginate Oligosaccharides from Laminaria japonica Biomass by a Novel Biofunctional Alginate Lyase with pH and Salt Tolerance

  • Lei Song,
  • Yan-Feng Guo,
  • Yi-Lei Wang,
  • Chuan-Bao Wang,
  • Jing-Hua Liu,
  • Guo-Qing Meng and
  • Zhi-Peng Wang

15 May 2023

Enzymatic alginate oligosaccharides were proved with various biological activities. Developing robust alginate lyase with high production is essential for its industrial application. In this study, a novel alginate lyase gene, AL07, was successfully...

  • Article
  • Open Access
50 Citations
6,017 Views
24 Pages

Alginate Oligosaccharides Affect Mechanical Properties and Antifungal Activity of Alginate Buccal Films with Posaconazole

  • Marta Szekalska,
  • Magdalena Wróblewska,
  • Monika Trofimiuk,
  • Anna Basa and
  • Katarzyna Winnicka

9 December 2019

Sodium alginate and its oligosaccharides through potential antifungal properties might improve the activity of antifungal drugs enhancing their efficacy and potentially reducing the frequency of application. Mucoadhesive buccal films are oral dosage...

  • Article
  • Open Access
106 Citations
14,304 Views
15 Pages

Purification and Characterization of a Bifunctional Alginate Lyase from Pseudoalteromonas sp. SM0524

  • Jian-Wei Li,
  • Sheng Dong,
  • Jie Song,
  • Chun-Bo Li,
  • Xiu-Lan Chen,
  • Bin-Bin Xie and
  • Yu-Zhong Zhang

21 January 2011

An alginate lyase-producing bacterial strain, Pseudoalteromonas sp. SM0524, was screened from marine rotten kelp. In an optimized condition, the production of alginate lyase from Pseudoalteromonas sp. SM0524 reached 62.6 U/mL, suggesting that strain...

  • Article
  • Open Access
25 Citations
4,263 Views
12 Pages

Expression and Characterization of an Alginate Lyase and Its Thermostable Mutant in Pichia pastoris

  • Suxiao Yang,
  • Zhemin Liu,
  • Xiaodan Fu,
  • Changliang Zhu,
  • Qing Kong,
  • Min Yang and
  • Haijin Mou

11 June 2020

Alginate is one of the most abundant polysaccharides in algae. Alginate lyase degrades alginate through a β-elimination mechanism to produce alginate oligosaccharides with special bioactivities. Improving enzyme activity and thermal stability ca...

  • Article
  • Open Access
10 Citations
3,308 Views
12 Pages

31 July 2023

Among the most studied natural polymers, alginate, a natural polysaccharide extracted from algae is well known due to its applications related to remarkable properties such as biocompatibility, biodegradability and low toxicity. In order to optimize...

  • Article
  • Open Access
26 Citations
5,222 Views
12 Pages

Radical Depolymerization of Alginate Extracted from Moroccan Brown Seaweed Bifurcaria bifurcata

  • Bouissil Soukaina,
  • EL Alaoui-Talibi Zainab,
  • Pierre Guillaume,
  • Rchid Halima,
  • Michaud Philippe,
  • El Modafar Cherkaoui and
  • Delattre Cédric

17 June 2020

The degradation of alginate extracted from Moroccan Bifurcaria bifurcata has not been fully established to date. In this work, we report the extraction and the characterization of alginate (ASBB) from the brown algae B. bifurcata, as well as the prod...

  • Article
  • Open Access
2 Citations
1,614 Views
12 Pages

Alginate lyases cleave the 1,4-glycosidic bond of alginate by eliminating sugar molecules from its bond. While earlier reported alginate lyases were primarily single catalytic domains, research on multi-module alginate lyases has been lfiguimited. Th...

  • Article
  • Open Access
24 Citations
4,920 Views
19 Pages

Degradation of Alginate by a Newly Isolated Marine Bacterium Agarivorans sp. B2Z047

  • Xun-Ke Sun,
  • Ya Gong,
  • Dan-Dan Shang,
  • Bang-Tao Liu,
  • Zong-Jun Du and
  • Guan-Jun Chen

4 April 2022

Alginate is the main component of brown algae, which is an important primary production in marine ecosystems and represents a huge marine biomass. The efficient utilization of alginate depends on alginate lyases to catalyze the degradation, and remai...

  • Review
  • Open Access
25 Citations
7,300 Views
20 Pages

Alginate Modification and Lectin-Conjugation Approach to Synthesize the Mucoadhesive Matrix

  • Arlina Prima Putri,
  • Francesco Picchioni,
  • Sri Harjanto and
  • Mochamad Chalid

13 December 2021

Alginates are natural anionic polyelectrolytes investigated in various biomedical applications, such as drug delivery, tissue engineering, and 3D bioprinting. Functionalization of alginates is one possible way to provide a broad range of requirements...

  • Article
  • Open Access
2 Citations
1,291 Views
31 Pages

Development of Covalently Functionalized Alginate–Pyrrole and Polypyrrole–Alginate Nanocomposites as 3D Printable Electroconductive Bioinks

  • Abraham Abbey Paul,
  • Olga Kryukov,
  • Anil Kumar Bandela,
  • Hamody Muadi,
  • Nurit Ashkenasy,
  • Smadar Cohen and
  • Robert S. Marks

1 July 2025

Electrically conductive hydrogels are gaining attention owing to their applications in biosensing, cellular interfaces, and tissue engineering. However, conventional hydrogels often lack adequate electrical conductivities. Here, we present two novel...

  • Review
  • Open Access
744 Citations
29,187 Views
19 Pages

Alginate in Wound Dressings

  • Blessing Atim Aderibigbe and
  • Buhle Buyana

Alginate is a biopolymer used in a variety of biomedical applications due to its favourable properties, such as biocompatibility and non-toxicity. It has been particularly attractive in wound healing applications to date. It can be tailored to materi...

  • Article
  • Open Access
66 Citations
9,718 Views
11 Pages

6 June 2016

Enzymatic hydrolysis of sodium alginate to produce alginate oligosaccharides has drawn increasing attention due to its advantages of containing a wild reaction condition, excellent gel properties and specific products easy for purification. However,...

  • Article
  • Open Access
9 Citations
3,158 Views
17 Pages

A Recombinant Alginate Lyase Algt1 with Potential in Preparing Alginate Oligosaccharides at High-Concentration Substrate

  • Qingping Liang,
  • Youtao Huang,
  • Zhemin Liu,
  • Mengshi Xiao,
  • Xinmiao Ren,
  • Tianhong Liu,
  • Hongyan Li,
  • Dongxing Yu,
  • Ying Wang and
  • Changliang Zhu

6 November 2023

Alginate lyase has been demonstrated as an efficient tool in the preparation of functional oligosaccharides (AOS) from alginate. The high viscosity resulting from the high concentration of alginate poses a limiting factor affecting enzymatic hydrolys...

  • Review
  • Open Access
326 Citations
36,969 Views
29 Pages

3D Cell Culture in Alginate Hydrogels

  • Therese Andersen,
  • Pia Auk-Emblem and
  • Michael Dornish

24 March 2015

This review compiles information regarding the use of alginate, and in particular alginate hydrogels, in culturing cells in 3D. Knowledge of alginate chemical structure and functionality are shown to be important parameters in design of alginate-base...

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