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34 Results Found

  • Article
  • Open Access
45 Citations
5,527 Views
8 Pages

3 December 2021

Several ecological data types, especially microbiome count data, are commonly sample-wise normalized before analysis to correct for sampling bias and other technical artifacts. Recently, we developed an algorithm for the normalization of ecological c...

  • Article
  • Open Access
10 Citations
3,926 Views
20 Pages

Effect of Dextranase and Dextranase-and-Nisin-Containing Mouthwashes on Oral Microbial Community of Healthy Adults—A Pilot Study

  • Chaiyavat Chaiyasut,
  • Sasithorn Sirilun,
  • Nucharee Juntarachot,
  • Piyachat Tongpong,
  • Worada Ouparee,
  • Bhagavathi Sundaram Sivamaruthi,
  • Sartjin Peerajan,
  • Rungaroon Waditee-Sirisattha,
  • Pinidphon Prombutara and
  • Phakkharawat Sittiprapaporn
  • + 2 authors

4 February 2022

This study analyzed the alteration of oral microbial composition in healthy subjects after using dextranase-containing mouthwash (DMW; Mouthwash formulation I) and dextranase-and-nisin-containing mouthwash (DNMW; Mouthwash formulation II). Eighteen p...

  • Article
  • Open Access
19 Citations
4,647 Views
15 Pages

Diet Is a Stronger Covariate than Exercise in Determining Gut Microbial Richness and Diversity

  • Eon-Joo Yun,
  • Saba Imdad,
  • Junho Jang,
  • Jinhan Park,
  • Byunghun So,
  • Jin-Hee Kim and
  • Chounghun Kang

16 June 2022

Obesity is a common metabolic disorder caused by a sedentary lifestyle, and a high-fat and a high-glucose diet in the form of fast foods. High-fat diet-induced obesity is a major cause of diabetes and cardiovascular diseases, whereas exercise and phy...

  • Article
  • Open Access
1 Citations
1,350 Views
15 Pages

The Potential of Mustard Seed Meal to Alleviate LPS-Induced Microbial Shifts in Weaned Piglets

  • Iulian A. Grosu,
  • Gina C. Pistol,
  • Daniela E. Marin and
  • Ionelia Taranu

11 December 2024

Mustard seed meal, an oil industry by-product, shows promise as a dietary additive in animal feed due to its rich content of bioactive compounds and antioxidant potential. The present study examined its impact on the gut microbiota of post-weaning pi...

  • Article
  • Open Access
12 Citations
4,742 Views
10 Pages

Ruminal Protozoal Populations of Angus Steers Differing in Feed Efficiency

  • Brooke A. Clemmons,
  • Sung B. Shin,
  • Timothy P. L. Smith,
  • Mallory M. Embree,
  • Brynn H. Voy,
  • Liesel G. Schneider,
  • Dallas R. Donohoe,
  • Kyle J. McLean and
  • Phillip R. Myer

27 May 2021

Feed accounts for as much as 70% of beef production costs, and improvement of the efficiency with which animals convert feed to product has the potential to have substantial financial impact on the beef industry. The rumen microbiome plays a key role...

  • Article
  • Open Access
2 Citations
2,760 Views
14 Pages

Characterization and Description of the Fecal Microbiomes of Pet Domestic Ferrets (Mustela putorius furo) Living in Homes

  • Elisa Scarsella,
  • J. Skyla Fay,
  • Guillaume Jospin,
  • Jessica K. Jarett,
  • Zhandra Entrolezo and
  • Holly H. Ganz

29 October 2023

The domestic ferret (Mustela putorius furo) is a popular companion pet in the United States, with an estimated population of 500,000. Despite being obligate carnivores with a fast digestive system, little is known about their gut microbiomes. This st...

  • Article
  • Open Access
5 Citations
3,807 Views
17 Pages

A Study of the Gut Bacterial Community of Reticulitermes virginicus Exposed to Chitosan Treatment

  • Telmah Telmadarrehei,
  • Juliet D. Tang,
  • Olanrewaju Raji,
  • Amir Rezazadeh,
  • Lakshmi Narayanan,
  • Rubin Shmulsky and
  • Dragica Jeremic

8 October 2020

A thorough understanding of microbial communities in the gut of lower termites is needed to develop target-specific and environmentally benign wood protection systems. In this study, the bacterial community from Reticulitermes virginicus was examined...

  • Article
  • Open Access
31 Citations
4,430 Views
16 Pages

8 January 2019

The study investigated the effect of grape seed (GS) meal, aflatoxin (AFB1), or their combination on the large intestine microbiota of weanling piglets. Twenty-four piglets were allocated into four groups based on diet composition: (1) Control group;...

  • Feature Paper
  • Article
  • Open Access
1 Citations
4,374 Views
12 Pages

Bacteria, Fungi, and Scalp Psoriasis: Understanding the Role of the Microbiome in Disease Severity

  • Jin-Young Choi,
  • Hyunseong Kim,
  • Kyung-Hyun Min,
  • Woo-Hyun Song,
  • Dong-Soo Yu,
  • Minho Lee and
  • Young-Bok Lee

16 August 2024

Background: Psoriasis is a chronic skin condition affected by genetic and environmental factors. Changes in the skin microbiome may affect the immune system and skin barrier functions, thereby contributing to the development and progression of psoria...

  • Communication
  • Open Access
1 Citations
2,750 Views
8 Pages

29 January 2023

Microbiologically influenced corrosion (MIC) of metal alloys is promoted by biofilms formed on metal surfaces. In the marine environment, MIC causes serious metal infrastructure problems, which lead to significant economic losses. In this study, we u...

  • Article
  • Open Access
24 Citations
5,785 Views
16 Pages

Dietary Protein, Fiber and Coffee Are Associated with Small Intestine Microbiome Composition and Diversity in Patients with Liver Cirrhosis

  • Shehnaz K. Hussain,
  • Tien S. Dong,
  • Vatche Agopian,
  • Joseph R. Pisegna,
  • Francisco A. Durazo,
  • Pedram Enayati,
  • Vinay Sundaram,
  • Jihane N. Benhammou,
  • Mazen Noureddin and
  • Jonathan P. Jacobs
  • + 5 authors

13 May 2020

The gut microbiome is a key factor in chronic liver disease progression. In prior research, we found that the duodenal microbiome was associated with sex, ethnicity, and cirrhosis complications. Here, we examined the association between diet and the...

  • Article
  • Open Access
39 Citations
6,282 Views
10 Pages

Effects of Smoking and Smoking Cessation on the Intestinal Microbiota

  • Marcus G. Sublette,
  • Tzu-Wen L. Cross,
  • Claudia E. Korcarz,
  • Kristin M. Hansen,
  • Sofia M. Murga-Garrido,
  • Stanley L. Hazen,
  • Zeneng Wang,
  • Madeline K. Oguss,
  • Federico E. Rey and
  • James H. Stein

14 September 2020

We evaluated associations of smoking heaviness markers and the effects of smoking cessation on the intestinal microbiota and cardiovascular disease risk factors in current smokers undertaking a quit attempt. Participants were current smokers enrolled...

  • Article
  • Open Access
6 Citations
3,568 Views
17 Pages

Captopril Alleviates Chondrocyte Senescence in DOCA-Salt Hypertensive Rats Associated with Gut Microbiome Alteration

  • Lok Chun Chan,
  • Yuqi Zhang,
  • Xiaoqing Kuang,
  • Mohamad Koohi-Moghadam,
  • Haicui Wu,
  • Theo Yu Chung Lam,
  • Jiachi Chiou and
  • Chunyi Wen

10 October 2022

Gut microbiota is the key controller of healthy aging. Hypertension and osteoarthritis (OA) are two frequently co-existing age-related pathologies in older adults. Both are associated with gut microbiota dysbiosis. Hereby, we explore gut microbiome a...

  • Article
  • Open Access
1 Citations
1,691 Views
12 Pages

Butyrate Producers in Very Low Birth Weight Infants with Neither Culture-Proven Sepsis nor Necrotizing Enterocolitis

  • Anucha Thatrimontrichai,
  • Manapat Praditaukrit,
  • Gunlawadee Maneenil,
  • Supaporn Dissaneevate,
  • Kamonnut Singkhamanan and
  • Komwit Surachat

11 April 2025

Background/Objectives: Severe infection (sInfection; either late-onset culture-proven sepsis or necrotizing enterocolitis) in very low birth weight (VLBW) infants increases mortality rates and may show long-term progression. The fecal microbiome comp...

  • Article
  • Open Access
650 Views
17 Pages

Comparative Characterization of Vaginal and Gut Microbiota in Late-Pregnancy Women with or Without Group B Streptococcus Colonization

  • Shuang Song,
  • Kaori Iino,
  • Mako Nakamura,
  • Maki Sato,
  • Maika Oishi,
  • Asami Ito and
  • Yoshihito Yokoyama

Group B Streptococcus (GBS) colonization during pregnancy is a major cause of neonatal infection, yet its microbial determinants remain unclear. This pilot study compared the vaginal and gut microbiota of late-pregnancy women with and without GBS col...

  • Article
  • Open Access
44 Citations
4,795 Views
17 Pages

Diet Influences the Oral Microbiota of Infants during the First Six Months of Life

  • Patrícia M. Oba,
  • Hannah D. Holscher,
  • Rose Ann Mathai,
  • Juhee Kim and
  • Kelly S. Swanson

5 November 2020

Background: Oral microorganisms contribute to oral health and disease, but few have studied how infant feeding methods affect their establishment. Methods: Infant (n = 12) feeding records and tongue and cheek swabs were collected within 48 h of birth...

  • Feature Paper
  • Article
  • Open Access
20 Citations
4,017 Views
12 Pages

Adherence to Gluten-Free Diet Restores Alpha Diversity in Celiac People but the Microbiome Composition Is Different to Healthy People

  • Orazio Palmieri,
  • Stefano Castellana,
  • Antonio Bevilacqua,
  • Anna Latiano,
  • Tiziana Latiano,
  • Anna Panza,
  • Rosanna Fontana,
  • Antonio Massimo Ippolito,
  • Giuseppe Biscaglia and
  • Carmela Lamacchia
  • + 8 authors

14 June 2022

Celiac disease (CD) is an autoimmune disease with the destruction of small intestinal villi, which occurs in genetically predisposed individuals. At the present moment, a gluten-free diet (GFD) is the only way to restore the functionality of gut muco...

  • Article
  • Open Access
2 Citations
1,844 Views
26 Pages

Combinatorial Effects of Cisplatin and PARP Inhibitor Olaparib on Survival, Intestinal Integrity, and Microbiome Modulation in Murine Model

  • Mitsuki Matsumura,
  • Hisako Fujihara,
  • Kanna Maita,
  • Moeko Miyakawa,
  • Yushi Sakai,
  • Ryoko Nakayama,
  • Yumi Ito,
  • Mitsuhiko Hasebe,
  • Koji Kawaguchi and
  • Yoshiki Hamada

30 January 2025

This study investigated the effects of the poly (ADP-ribose) polymerase (PARP) inhibitor Olaparib, alone and in combination with cisplatin, on intestinal integrity, survival, and microbiome composition using a murine model. Statistical analyses were...

  • Article
  • Open Access
1 Citations
978 Views
12 Pages

Differences in Vaginal Microbiota Composition Between Infertile and Fertile Patients: A Prospective Study

  • Pei-Chen Chen,
  • Shih-Fen Chen,
  • Wei-Tung Hung,
  • Yu-Ying Lin,
  • Ling-Chun Lin,
  • Jen-Hung Wang and
  • Pao-Chu Chen

9 October 2025

Background/Objectives: Dysbiosis of the vaginal microbiota, particularly the loss of Lactobacillus spp. dominance, is linked to female infertility. While community state types (CSTs) I–III and V have been studied extensively, CST IV remains und...

  • Article
  • Open Access
1,069 Views
16 Pages

30 June 2025

Objectives: The aim of this study was to assess the taxonomic diversity of the microbiota associated with periapical lesions of endodontic origin and to determine whether microbial profiles vary across different populations and clinical characteristi...

  • Article
  • Open Access
1 Citations
1,395 Views
15 Pages

Remodeling of Gut Microbial Networks After Sulforaphane Supplementation in Patients with Chronic Kidney Disease

  • Marcia Ribeiro,
  • Julie Ann Kemp,
  • Karen Salve Coutinho-Wolino,
  • Ludmila F. M. F. Cardozo,
  • Pedro Almeida,
  • Júnia Schultz,
  • Lia S. Nakao,
  • Maria Eduarda S. Costa,
  • Fernanda Kussi and
  • Denise Mafra
  • + 1 author

2 September 2025

Background and Objectives: Chronic kidney disease (CKD) is closely associated with gut dysbiosis, and sulforaphane (SFN), a bioactive compound found in cruciferous vegetables, may help to mitigate this condition. Methods: These are secondary explorat...

  • Article
  • Open Access
7 Citations
3,623 Views
21 Pages

The Functional Biogeography of eDNA Metacommunities in the Post-Fire Landscape of the Angeles National Forest

  • Savanah Senn,
  • Sharmodeep Bhattacharyya,
  • Gerald Presley,
  • Anne E. Taylor,
  • Bruce Nash,
  • Ray A. Enke,
  • Karen B. Barnard-Kubow,
  • Jillian Ford,
  • Brandon Jasinski and
  • Yekaterina Badalova

Wildfires have continued to increase in frequency and severity in Southern California due in part to climate change. To gain a further understanding of microbial soil communities’ response to fire and functions that may enhance post-wildfire re...

  • Article
  • Open Access
84 Citations
13,361 Views
22 Pages

Impact of Different Exercise Modalities on the Human Gut Microbiome

  • Dierdra Bycura,
  • Anthony C. Santos,
  • Arron Shiffer,
  • Shari Kyman,
  • Kyle Winfree,
  • Jay Sutliffe,
  • Talima Pearson,
  • Derek Sonderegger,
  • Emily Cope and
  • J. Gregory Caporaso

21 January 2021

In this study we examined changes to the human gut microbiome resulting from an eight-week intervention of either cardiorespiratory exercise (CRE) or resistance training exercise (RTE). Twenty-eight subjects (21 F; aged 18–26) were recruited for our...

  • Article
  • Open Access
1 Citations
2,173 Views
12 Pages

mbX: An R Package for Streamlined Microbiome Analysis

  • Utsav Lamichhane and
  • Jeferson Lourenco

29 May 2025

Here, we introduce the mbX package: an R-based tool designed to streamline 16S rRNA gene microbiome data analysis following taxonomic classification. It automates key post-sequencing steps, including taxonomic data cleaning and visualization, address...

  • Article
  • Open Access
1,599 Views
11 Pages

Influence of Elution Characteristics of Steelmaking Slags on Major Bacterial Communities in Biofilms

  • Akiko Ogawa,
  • Yukino Mizutani,
  • Reiji Tanaka,
  • Tatsuki Ochiai,
  • Ruu Ohashi,
  • Nobumitsu Hirai and
  • Masanori Suzuki

1 September 2023

Steelmaking slags are prospective base materials for seaweed beds, resulting from a continuous process of biofouling, starting from biofilm formation and leading to growing algae. While focusing on biofilm formation, we investigated specific features...

  • Article
  • Open Access
15 Citations
7,214 Views
15 Pages

Comparison between Egg Intake versus Choline Supplementation on Gut Microbiota and Plasma Carotenoids in Subjects with Metabolic Syndrome

  • Minu S. Thomas,
  • Marissa DiBella,
  • Christopher N. Blesso,
  • Olga Malysheva,
  • Marie Caudill,
  • Maria Sholola,
  • Jessica L. Cooperstone and
  • Maria Luz Fernandez

11 March 2022

We previously demonstrated that intake of three eggs/d for 4 weeks increased plasma choline and decreased inflammation in subjects with metabolic syndrome (MetS). The purpose of the current study was to further explore the effects of phosphatidylchol...

  • Article
  • Open Access
14 Citations
5,290 Views
13 Pages

Oral Ferric Maltol Does Not Adversely Affect the Intestinal Microbiome of Patients or Mice, but Ferrous Sulphate Does

  • Awad Mahalhal,
  • Alessandra Frau,
  • Michael D. Burkitt,
  • Umer Z. Ijaz,
  • Christopher A. Lamb,
  • John C. Mansfield,
  • Stephen Lewis,
  • D. Mark Pritchard and
  • Chris S. Probert

30 June 2021

Background and Aims: Altering dietary ferrous sulphate (FS) consumption exacerbates a murine model of colitis and alters the intestinal microbiome. We investigated the impact of oral ferric maltol (FM) and FS on mice with dextran sodium sulphate (DSS...

  • Article
  • Open Access
1 Citations
1,926 Views
16 Pages

21 December 2024

Background: Effective management of primary apical periodontitis depends on understanding the dynamic interactions within the root canal microbiome. This study aimed to investigate the effect of sequential antimicrobial phases on the root canal micro...

  • Data Descriptor
  • Open Access
1 Citations
2,789 Views
13 Pages

7 April 2024

Ironwood trees, which are of great importance for the economy and environment of tropical areas, were first discovered to suffer from a slow progressive dieback in Guam in 2002, later referred to as ironwood tree decline (IWTD). A variety of biotic f...

  • Article
  • Open Access
307 Views
15 Pages

Oral Microbiota Alterations and Potential Salivary Biomarkers in Colorectal Cancer: A Next-Generation Sequencing Study

  • Salih Maçin,
  • Özben Özden,
  • Rugıyya Samadzade,
  • Esra Saylam,
  • Nurullah Çiftçi,
  • Uğur Arslan and
  • Serdar Yormaz

30 December 2025

Colorectal cancer (CRC) has a high mortality rate worldwide. Oral and intestinal microbiota members may have an effect on gastrointestinal tumors’ pathogenesis, particularly in CRC. Designed as a pilot study, this study’s aim was to inves...

  • Article
  • Open Access
17 Citations
4,370 Views
21 Pages

21 November 2022

The role of gut microbes has been suggested in type 2 diabetes (T2DM) risk. However, their results remain controversial. We hypothesized that Asians with T2DM had different fecal bacterial compositions, co-abundance networks, and metagenome functions...

  • Article
  • Open Access
65 Views
27 Pages

Comparative Analysis of Oral Microbiome in Indian Type 2 Diabetes Mellitus (T2DM) and Periodontitis Cohorts

  • Meenakshi Murmu,
  • Rajshri Singh,
  • Rajesh Gaikwad,
  • Akshaya Banodkar,
  • Sagar Barage,
  • Preethi Sudhakara and
  • Aruni Wilson Santhosh Kumar

23 January 2026

Background: Type 2 diabetes mellitus (T2DM) and periodontitis are highly prevalent immune-inflammatory diseases that interact bidirectionally. However, how early-onset T2DM, periodontitis, and adverse lifestyle behaviors collectively remodel the ging...

  • Article
  • Open Access
430 Views
20 Pages

Dietary Geranylgeraniol Mitigates Pain-Associated Behaviors via Improving Mitochondrial Function and Colon Integrity and Suppressing Neuroinflammation in Male Diabetic Neuropathy Rats

  • Chwan-Li Shen,
  • Xiaobo Liu,
  • Jay J. Cao,
  • Volker Neugebauer,
  • Jonathan M. Miranda,
  • Moamen M. Elmassry,
  • Dale M. Dunn and
  • Jannette M. Dufour

17 December 2025

Growing evidence highlights the links between diabetic neuropathy (DNP), gut dysbiosis, mitochondrial dysfunction and neuroinflammation in colon and bone microstructure deterioration. Geranylgeraniol (GG) shows neuroprotective and osteoprotective cap...

  • Article
  • Open Access
1 Citations
1,254 Views
13 Pages

11 December 2024

The removal of nitrogen compounds in wastewater has been successfully developed with various activated sludge-based processes. Microorganisms immobilized in media would enhance biological efficiency by the increase in biomass concentration; however,...