154,277 Results Found

Echinococcus granulosus sensu lato (s.l.) is the causative agent of cystic echinococcosis in animals and humans. Different E. granulosuss.l. genotypes exhibit great diversity in their life cycle, host selectivity and pathogenicity. For this reason, t...

Considering the intrinsic benefits of power line communications, the long-lasting lifetime of industrial systems and the growth of IoT, PLC technologies will be part of the worldwide industrial landscape for many decades. This paper discusses the his...

Rotavirus species A (RVA) is a major cause of acute viral gastroenteritis in young humans and diverse animal species. The study of the genetic characteristics of RVAs that infect rabbits (Oryctolagus cuniculus) (lapine strain [LRV]) has been limited,...

This paper presents a comparison between the partial discharge (PD) characteristics of g3 and dry air for gas-insulated switchgears. PD signals were measured with a conventional method according to IEC 60270 and an ultra-high frequency (UHF) method....

Equine rotavirus A (ERVA) is the leading cause of diarrhea in foals, with G3P[12] and G14P[12] genotypes being the most prevalent. Recently, equine G3-like RVA was recognized as an emerging infection in children, and a group B equine rotavirus (ERVB)...

Designed ankyrin repeat protein (DARPin) G3 is an engineered scaffold protein. This small (14.5 kDa) targeting protein binds with high affinity to human epidermal growth factor receptor 2 (HER2). HER2 is overexpressed in several cancers. The use of t...

Combined computational and experimental strategies for the systematic design of chemical sensor arrays using carbonitrile neutral receptors are presented. Binding energies of acetonitrile, n-pentylcarbonitrile and malononitrile with Ca(II), Mg(II), B...

Grade 3 (G3) neuroendocrine tumors (NETs) are a novel category among digestive neuroendocrine neoplasms, characterized by Ki-67 >20% and a well-differentiated morphology, presenting high intra-tumor heterogeneity. We aimed to explore the role of d...

Background: In 2017, the World Health Organization (WHO) defined a new category of pancreatic neuroendocrine neoplasms named G3 pancreatic neuroendocrine tumors (p-NETs), whose surgical outcomes, long-term survivals and staging systems have not been...

Well-differentiated grade 3 neuroendocrine tumors (NET G3) have been distinguished from poorly differentiated neuroendocrine carcinomas (NEC) in the most current WHO classifications. Commonly applied first-line chemotherapy protocols with cisplatin o...

Provably correct and computationally efficient path planning in the presence of various constraints is essential for autonomous driving and agile maneuvering of mobile robots. In this paper, we consider the planning of G 3-continuous planar paths...

Polymorphisms in drug-metabolizing enzymes might not completely explain inter-individual differences in toxicity profiles of patients with colorectal cancer (CRC) that receive folinic acid/5-fluorouracil/oxaliplatin (FOLFOX4). Recent data indicate th...

This paper presents a performance analysis based on a practical approach of narrowband communication through power lines (Power Line Communication—PLC) to the last-mile industrial environment. A kit for developing PLC based applications, in acc...

Background: Grade 3 gastro-entero-pancreatic neuroendocrine tumors (G3 GEP-NET) are poorly characterized in terms of molecular features and response to treatments. Methods: Patients with G3 GEP-NET were included if they received capecitabine and temo...

Narrowband (NB) powerline communication (PLC) is extensively adopted by utilities for the communication in advanced metering infrastructure (AMI) systems. PLC technology needs to overcome channel disturbances present in certain grid segments. This st...

The aim of this paper was to assess the differences in tissue response to implantation during 15, 30 and 45 days in the subcutaneous connective tissue of Wistar rats from three biomaterials: Angelus MTA®, Theracal LC®, and Angelus MTA® to which 25% b...

Squamous cell carcinoma (SCC) remains a main cause of mortality in patients with neck and head cancers, with poor prognosis and increased prevalence despite of available therapies. Recent studies have identified a role of cyclooxygenases, particularl...

One of the intensively developed tools for cancer therapy is drug-releasing matrices. Polyamidoamine dendrimers (PAMAM) are commonly used as nanoparticles to increase the solubility, stability and retention of drugs in the human body. Most often, dru...

Background: Neuroendocrine neoplasms (NENs) are a rare group of tumors with a different clinical course, prognosis and location. Radioligand therapy (RLT) can be used as a first or second line of treatment. It is registered in gastroenteropancreatic...

Recent achievement in anticancer therapy considers the application of repurposed drugs in optimal combinations with the use of specific carriers for their targeted delivery. As a result, new optimized medications with reduced side effects can be obta...

Glioblastoma multiforme (GBM) is the most malignant type of central nervous system tumor that is resistant to all currently used forms of therapy. Thus, more effective GBM treatment strategies are being investigated, including combined therapies with...

Fifth-generation (5G) technology is anticipated to allow a slew of novel applications across a variety of industries. The wireless communication of the 5G and Beyond-5G (B5G) networks will accommodate a wide variety of services and user expectations,...

Neuroendocrine tumors (NETs) are rare neoplasms with a wide spectrum of clinical behavior, from the long survival of well-differentiated NETs to the dismal prognosis of high-grade neuroendocrine carcinomas (NECs), being G3 NETs a recently recognized...

As the deployment of 5G mobile radio networks gains momentum across the globe, the wireless research community is already planning the successor of 5G. In this paper, we highlight the shortcomings of 5G in meeting the needs of more data-intensive, lo...

Tuberculosis (TB) has various clinical presentations; pulmonary TB (PTB) affects only the lungs, whereas extrapulmonary TB involves other organs, including pleural TB (PLTB). Immunological studies of patients with extrapulmonary TB primarily focus on...

In a prior issue of the Journal of Intelligence, I argued that the most important scientific issue in intelligence research was to identify specific abilities with validity beyond g (i.e., variance common to mental tests) (Coyle, T.R. Predictive vali...

Genomic DNA methylation is involved in many diseases and is expected to be a specific biomarker for even the pre-symptomatic diagnosis of many diseases. Thus, a rapid and inexpensive detection method is required for disease diagnosis. We have previou...

As many as 700,000 unique sequences in the human genome are predicted to fold into G-quadruplexes (G4s), non-canonical structures formed by Hoogsteen guanine–guanine pairing within G-rich nucleic acids. G4s play both physiological and pathologi...

The 3rd Generation Partnership Project (3GPP) evolution of mobile communication technologies from 5G to 6G has been a transformative journey spanning a decade, shaped by six releases from Release 15 to Release 20. This article provides a retrospectiv...

The coronavirus disease 2019 (COVID-19) pandemic has severely affected people’s lives worldwide in an unexpected manner. According to the World Health Organization (WHO), several viral epidemics continue to occur and pose a significant public h...

In this paper, emerging 5G mobile services are investigated and categorized from the perspective of not service providers, but end-users. The development of 5G mobile services is based on an intensive analysis of the global trends in mobile services....

The guanine base in nucleic acids is, among the other bases, the most susceptible to being converted into 8-Oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) when exposed to reactive oxygen species. In double-helix DNA, 8-oxodG can pair with adenine;...

Determining the position of ourselves or our assets has always been important to humans. Technology has helped us, from sextants to outdoor global positioning systems, but real-time indoor positioning has been a challenge. Among the various solutions...

Smart farming and precision agriculture rely on the different components of IoT, such as sensors, drones, and robotic devices. IoT in agriculture is the network of interconnected devices that corresponds in real time, simultaneously, to gather, analy...

This article provides an overview of the fifth generation of cellular communications (5G) and beyond. It presents the transmission techniques of current 5G communications and those expected of future developments, namely a brief study of non-orthogon...

This study investigates the impact of factors (network coverage, customer service, video calls, and downloading Speed) of 3G and 4G telecommunication services performance on customer satisfaction in the Punjab region of Pakistan. This research indica...

The Fifth generation (5G) network is projected to support large amount of data traffic and massive number of wireless connections. Different data traffic has different Quality of Service (QoS) requirements. 5G mobile network aims to address the limit...

The 5G cellular network comes with a promise to provide a very high data rate at low latency, which is becoming critical for advancing technologies. Mobile operators are currently deploying the 5G cellular network worldwide. However, because of limit...

Cytosine methylation within the 5′-C-phosphate-G-3′ sequence of nucleotides (called CpG methylation) is a well-known epigenetic modification of genomic DNA that plays an important role in gene expression and development. CpG methylation i...

This paper analyzes practical solutions for implementing 5G/6G and Digital Terrestrial Television (DTT) network coexistence in the UHF band. Two potential scenarios are explored using the case study of a nationwide DTT network: spectrum splitting and...

Engineering of fragment crystallizable (Fc) domains of therapeutic immunoglobulin (IgG) antibodies to eliminate their immune effector functions while retaining other Fc characteristics has numerous applications, including blocking antigens on Fc gamm...

This comment argues that an important issue in intelligence research is to identify constructs with validity beyond g, and that non-g residuals of tests represent a promising target.

The classification of services in 5G/B5G (Beyond 5G) networks has become important for telecommunications service providers, who face the challenge of simultaneously offering a better Quality of Service (QoS) in their networks and a better Quality of...

Pseudorabies, also known as Aujezsky’s disease, is an acute viral infection caused by pseudorabies virus (PRV). Swine are one of the natural hosts of pseudorabies and the disease causes huge economic losses in the pig industry. The establishmen...

Background: The differential diagnosis of immunoglobulin G4-sclerosing cholangitis (IgG4-SC) from primary sclerosing cholangitis (PSC) or cholangiocarcinoma (CCA) is important. In this study, we aimed to find the best combinations of serum IgG subcla...

The terahertz (THz) frequency bands are being explored as a potential means of enabling an ultra-high transmission capacity in sixth-generation (6G) radio-access networks (RAN) because higher frequencies offer broader bandwidths. When utilized in wir...

G-quadruplex (G4) oligonucleotides are higher-order DNA and RNA secondary structures of enormous relevance due to their implication in several biological processes and pathological states in different organisms. Strategies aiming at modulating human...

Glycoprotein E (gE) and glycoprotein I (gI) are expressed as a heterodimer on the surface of Herpes simplex virus (HSV). Glycoprotein E binds Fc domain of immunoglobulin G (IgG) and inhibits activities mediated by the IgG Fc domain, contributing to i...

APOBEC3G (A3G) restricts HIV-1 replication primarily by reducing viral cDNA and inducing G-to-A hypermutations in viral cDNA. HIV-1 encodes virion infectivity factor (Vif) to counteract A3G primarily by excluding A3G viral encapsidation. Even though...

Mature B cells notably diversify immunoglobulin (Ig) production through class switch recombination (CSR), allowing the junction of distant “switch” (S) regions. CSR is initiated by activation-induced deaminase (AID), which targets cytosin...