You are currently viewing a new version of our website. To view the old version click .

774 Results Found

  • Article
  • Open Access
2 Citations
3,817 Views
13 Pages

Background: Despite the implementation of various preventive measures, India continues to experience an alarmingly high under-five mortality rate (U5MR). The most recent nationwide data on U5MRs has provided an opportunity to re-examine the associate...

  • Article
  • Open Access
1,422 Views
22 Pages

4 October 2024

Background/Objectives: In Korea’s emergency medical system, when an emergency patient arises, patients receive on-site treatment and care during transport at the pre-hospital stage, followed by inpatient treatment upon hospitalization. From the...

  • Article
  • Open Access
10 Citations
3,886 Views
14 Pages

Modeling Recidivism through Bayesian Regression Models and Deep Neural Networks

  • Rolando de la Cruz,
  • Oslando Padilla,
  • Mauricio A. Valle and
  • Gonzalo A. Ruz

17 March 2021

This study aims to analyze and explore criminal recidivism with different modeling strategies: one based on an explanation of the phenomenon and another based on a prediction task. We compared three common statistical approaches for modeling recidivi...

  • Article
  • Open Access
6 Citations
3,751 Views
15 Pages

7 September 2022

This study involved conducting a survival analysis by fitting a Cox proportional hazards model to Korea Labor Panel data to analyze the impact of parental job loss on children’s delayed admission to colleges and universities in South Korea, usi...

  • Article
  • Open Access
1 Citations
1,268 Views
13 Pages

13 May 2025

Issues related to the duration of university studies have attracted the interest of many researchers from different scientific fields, as far back as the middle of the 20th century. In this study, a Survival Analysis methodology and, more specificall...

  • Article
  • Open Access
676 Views
12 Pages

14 July 2025

The Cox proportional hazards (PH) model is widely used because it models the covariates to the hazard through a log-linear effect. However, exploring flexible effects becomes desirable within the Cox PH framework when only a monotonic relationship be...

  • Article
  • Open Access
19 Citations
3,121 Views
13 Pages

Metformin Attenuates Osteoporosis in Diabetic Patients with Carcinoma in Situ: A Nationwide, Retrospective, Matched-Cohort Study in Taiwan

  • Chieh-Hua Lu,
  • Chi-Hsiang Chung,
  • Feng-Chih Kuo,
  • Kuan-Chan Chen,
  • Chia-Hao Chang,
  • Chih-Chun Kuo,
  • Chien-Hsing Lee,
  • Sheng-Chiang Su,
  • Jhih-Syuan Liu and
  • Fu-Huang Lin
  • + 5 authors

2 September 2020

Patients with diabetes are at increased risk of cancer development and osteoporosis. Metformin is an effective agent for diabetes management. Epidemiological studies have identified an association between metformin use and cancer prevention. This art...

  • Article
  • Open Access
2 Citations
1,622 Views
13 Pages

Identifying the Key Hazards behind Website Drop-Offs by Solving a Survival Problem

  • Judah Soobramoney,
  • Retius Chifurira,
  • Knowledge Chinhamu and
  • Temesgen Zewotir

16 July 2023

Within the modern era, corporates are compelled to own an appealing and effective website to survive and thrive within the competitive global digital marketplace. Whilst there are several web metrics to focus on, a key focus area of web analytics is...

  • Article
  • Open Access
2 Citations
2,152 Views
11 Pages

6 October 2023

Many African nations continue to grapple with persistently high under-five child mortality rates, particularly those situated in the Sub-Saharan region, including South Africa. A multitude of socio-economic factors are identified as key contributors...

  • Feature Paper
  • Article
  • Open Access
2 Citations
3,558 Views
10 Pages

18 September 2024

The classical Cox model is the most popular procedure for studying right-censored data in survival analysis. However, it is based on the fundamental assumption of proportional hazards (PH). Modified Cox models, stratified and extended, have been wide...

  • Article
  • Open Access
1 Citations
3,446 Views
14 Pages

20 October 2018

Chronic diseases represented by circulatory diseases have gradually become the main types of diseases affecting the health of our population. Establishing a circulatory system disease prediction model to predict the occurrence of diseases and control...

  • Article
  • Open Access
2 Citations
2,091 Views
20 Pages

Angiosome-Targeted Infrapopliteal Angioplasty: Impact on Clinical Outcomes—An Observational Study

  • Mircea Ionut Popitiu,
  • Vlad Adrian Alexandrescu,
  • Giacomo Clerici,
  • Stefan Ionac,
  • Gloria Gavrila-Ardelean,
  • Miruna Georgiana Ion and
  • Mihai Edmond Ionac

2 February 2024

Background: Revascularization based on the angiosome concept (AC) is a controversial subject because there is currently no clear evidence of its efficacy, due to the heterogeneity of patients (multiple and diverse risk factors and comorbidities, mult...

  • Article
  • Open Access
4 Citations
2,954 Views
7 Pages

Clinical Course of Children with Chronic Suppurative Lung Disease or Bronchiectasis Infected with Pseudomonas aeruginosa

  • Elpiniki Kartsiouni,
  • Stylianos Chatzipanagiotou,
  • Angeliki Galani,
  • Dafni Moriki,
  • Olympia Sardeli,
  • Spyridon Prountzos,
  • Efthymia Alexopoulou,
  • Ioanna Loukou,
  • Kostas N. Priftis and
  • Konstantinos Douros

25 November 2022

Children with chronic wet cough and without cystic fibrosis (non-CF) may suffer from chronic suppurative lung disease (CSLD) or bronchiectasis. Pseudomonas aeruginosa (Pa) can be one of the offending microbes in these children. The present study aime...

  • Article
  • Open Access
6 Citations
2,467 Views
13 Pages

Preoperative Nodal US Features for Predicting Recurrence in N1b Papillary Thyroid Carcinoma

  • Na Lae Eun,
  • Jeong-Ah Kim,
  • Hye Mi Gweon,
  • Ji Hyun Youk and
  • Eun Ju Son

30 December 2021

This study aimed to investigate whether preoperative ultrasonographic (US) features of metastatic lymph nodes (LNs) are associated with tumor recurrence in patients with N1b papillary thyroid carcinoma (PTC). We enrolled 692 patients (mean age, 41.9...

  • Article
  • Open Access
712 Views
27 Pages

A Bivariate Copula–Driven Multi-State Model for Statistical Analysis in Medical Research

  • Hugo Brango,
  • Roger Tovar-Falón and
  • Guillermo Martínez-Flórez

24 September 2025

We develop and evaluate a copula-based multistate model for illness–death processes with dependent transition times. The framework couples Cox proportional hazards models for the marginal transition intensities with Archimedean copulas to captu...

  • Brief Report
  • Open Access
3 Citations
3,302 Views
8 Pages

23 February 2022

(1) Background: Fidaxomicin has been shown to significantly reduce Clostridioides difficile infection (CDI) recurrences rates in randomized, controlled trials. However, national data from the Veterans Affairs has called the real-world applicability o...

  • Article
  • Open Access
2 Citations
1,847 Views
10 Pages

14 July 2023

(1) Background: Considering recent advances in both cancer and sepsis management, we chose to evaluate the associated factors for occurrence of septic acute kidney injury in cancer patients using a nationwide population-based cohort data. (2) Methods...

  • Article
  • Open Access
11 Citations
2,876 Views
13 Pages

8 January 2021

The use of hydraulic silicate cements (HSCs) for vital pulp therapy has been found to release calcium and hydroxyl ions promoting pulp tissue healing and mineralized tissue formation. The present study investigated whether HSCs such as mineral trioxi...

  • Article
  • Open Access
17 Citations
3,759 Views
13 Pages

The Effects of Hyperuricemia on the Prognosis of IgA Nephropathy are More Potent in Females

  • Tae Ryom Oh,
  • Hong Sang Choi,
  • Chang Seong Kim,
  • Kyung Pyo Kang,
  • Young Joo Kwon,
  • Sung Gyun Kim,
  • Seong Kwon Ma,
  • Soo Wan Kim and
  • Eun Hui Bae

8 January 2020

Hyperuricemia is a potential risk factor for immunoglobulin A nephropathy (IgAN) progression but its sex-specific effects on IgAN progression remain unclear. This study aimed to determine the effect of serum uric acid on IgAN progression and whether...

  • Article
  • Open Access
33 Citations
8,562 Views
12 Pages

Dietary Protein Intake, Protein Energy Wasting, and the Progression of Chronic Kidney Disease: Analysis from the KNOW-CKD Study

  • Sung Woo Lee,
  • Yong-Soo Kim,
  • Yeong Hoon Kim,
  • Wookyung Chung,
  • Sue K. Park,
  • Kyu Hun Choi,
  • Curie Ahn and
  • Kook-Hwan Oh

8 January 2019

Studies on the effect of dietary protein intake (DPI) on chronic kidney disease (CKD) progression, along with the potential hazard of protein-energy wasting (PEW), are scarce. We evaluated the association between DPI and kidney function both cross-se...

  • Article
  • Open Access
3,532 Views
11 Pages

26 November 2021

This paper presents an algorithm for learning local Weibull models, whose operating regions are represented by fuzzy rules. The applicability of the proposed method is demonstrated in estimating the mortality rate of the COVID-19 pandemic. The reprod...

  • Article
  • Open Access
10 Citations
3,427 Views
13 Pages

A Spatial Survival Model for Risk Factors of Under-Five Child Mortality in Kenya

  • Kilemi Daniel,
  • Nelson Owuor Onyango and
  • Rachel Jelagat Sarguta

Child mortality is high in Sub-Saharan Africa compared to other regions in the world. In Kenya, the risk of mortality is assumed to vary from county to county due to diversity in socio-economic and even climatic factors. Recently, the country was spl...

  • Brief Report
  • Open Access
6 Citations
3,613 Views
8 Pages

Maternal intrapartum fever can lead to various maternal and neonatal complications and is attributed to various etiologies including infectious and non-infectious processes. In this study, we evaluated whether intrapartum fever affects the offspring&...

  • Article
  • Open Access
9 Citations
4,686 Views
14 Pages

Prognostic Effect of Inflammatory Genes on Stage I–III Colorectal Cancer—Integrative Analysis of TCGA Data

  • Eun Kyung Choe,
  • Sangwoo Lee,
  • So Yeon Kim,
  • Manu Shivakumar,
  • Kyu Joo Park,
  • Young Jun Chai and
  • Dokyoon Kim

11 February 2021

Background inflammatory status indicators have been reported as prognostic biomarkers of colorectal cancer (CRC). However, since inflammatory interactions with the colon involve various modes of action, the biological mechanism linking inflammation a...

  • Article
  • Open Access
21 Citations
4,235 Views
13 Pages

Comparison of the Clinical Implications among Five Different Nutritional Indices in Patients with Lupus Nephritis

  • Sung Soo Ahn,
  • Juyoung Yoo,
  • Seung Min Jung,
  • Jason Jungsik Song,
  • Yong-Beom Park and
  • Sang-Won Lee

27 June 2019

Systemic lupus erythematosus (SLE) is characterized with aberrant responses in the immune systems and lupus nephritis (LN) is one of the most serious complications of SLE. This study evaluated the clinical significance of different nutritional indice...

  • Article
  • Open Access
2 Citations
2,032 Views
9 Pages

17 February 2023

Objective: We opted to investigate whether fetal growth restriction (FGR) in dichorionic–diamniotic twins is a risk factor for long-term cardiovascular morbidity in offspring. Study design: A population-based retrospective cohort study, compari...

  • Article
  • Open Access
10 Citations
2,377 Views
8 Pages

8 November 2019

The aim of this study was to evaluate perinatal outcome and long-term offspring gastrointestinal morbidity of women with celiac disease. Perinatal outcomes, as well as long-term gastrointestinal morbidity of offspring of mothers with and without celi...

  • Article
  • Open Access
3 Citations
5,213 Views
13 Pages

Klatskin Tumor: A Survival Analysis According to Tumor Characteristics and Inflammatory Ratios

  • Vlad-Ionuţ Nechita,
  • Emil Moiş,
  • Luminiţa Furcea,
  • Mihaela-Ancuţa Nechita and
  • Florin Graur

5 December 2022

Background and Objectives: The aim was to evaluate the association of inflammatory biomarkers with resectability and overall survival in hilar cholangiocarcinoma. Materials and Methods: We conducted a retrospective cohort study over 72 consecutive su...

  • Article
  • Open Access
5 Citations
2,952 Views
15 Pages

Appendectomy and Non-Typhoidal Salmonella Infection: A Population-Based Matched Cohort Study

  • Den-Ko Wu,
  • Kai-Shan Yang,
  • James Cheng-Chung Wei,
  • Hei-Tung Yip,
  • Renin Chang,
  • Yao-Min Hung and
  • Chih-Hsin Hung

2 April 2021

The potential association between appendectomy and non-typhoidal Salmonella (NTS) infection has not been elucidated. We hypothesized that appendectomy may be associated with gut vulnerability to NTS. The data were retrospectively collected from the T...

  • Article
  • Open Access
29 Citations
5,332 Views
13 Pages

Objective: The aim of this study is to assess the risk factors for incident functional disability among long-term evacuees of Iitate village after Great East Japan Earthquake and nuclear disaster (GEJE). We also investigated the effectiveness of exer...

  • Article
  • Open Access
9 Citations
4,067 Views
13 Pages

Loop Diuretics Are Associated with Increased Risk of Hospital-Acquired Acute Kidney Injury in Adult Patients: A Retrospective Study

  • Liping Zhou,
  • Yanqin Li,
  • Qi Gao,
  • Yuxin Lin,
  • Licong Su,
  • Ruixuan Chen,
  • Yue Cao,
  • Ruqi Xu,
  • Fan Luo and
  • Peiyan Gao
  • + 6 authors

24 June 2022

Background: The association between loop diuretics and acute kidney injury (AKI) remains unclear. Methods: The population studied was selected from the Epidemiology of AKI in Chinese Hospitalized patients (EACH) study. Exposure to loop diuretics was...

  • Article
  • Open Access
1 Citations
2,793 Views
10 Pages

3 February 2023

Background: Studies on the association between solute, nutrition and fluid intakes and mortality and later kidney function in critically ill acute kidney injury (AKI) patients receiving continuous veno-venous hemodialysis (CVVHD) are scarce. Methods:...

  • Article
  • Open Access
5 Citations
2,666 Views
11 Pages

Identification of Clinical Phenotypes and Related Survival in Patients with Large HCCs

  • Brian I. Carr,
  • Vito Guerra,
  • Rossella Donghia,
  • Fabio Farinati,
  • Edoardo G. Giannini,
  • Luca Muratori,
  • Gian Ludovico Rapaccini,
  • Maria Di Marco,
  • Eugenio Caturelli and
  • Marco Zoli
  • + 16 authors

3 February 2021

Background. Hepatocellular carcinoma (HCC) factors, especially maximum tumor diameter (MTD), tumor multifocality, portal vein thrombosis (PVT), and serum alpha-fetoprotein (AFP), influence survival. Aim. To examine patterns of tumor factors in large...

  • Article
  • Open Access
8 Citations
2,765 Views
20 Pages

Adopting New Machine Learning Approaches on Cox’s Partial Likelihood Parameter Estimation for Predictive Maintenance Decisions

  • David R. Godoy,
  • Víctor Álvarez,
  • Rodrigo Mena,
  • Pablo Viveros and
  • Fredy Kristjanpoller

15 January 2024

The Proportional Hazards Model (PHM) under a Condition-Based Maintenance (CBM) policy is used by asset-intensive industries to predict failure rate, reliability function, and maintenance decisions based on vital covariates data. Cox’s partial l...

  • Article
  • Open Access
5,678 Views
13 Pages

21 August 2025

Background: Evidence linking dietary fiber intake with cancer risk and mortality is equivocal. Objective: We investigated the relationship between dietary fiber intake and all-cause, cancer, and cardiovascular disease (CVD) mortalities in US adults &...

  • Article
  • Open Access
4 Citations
2,538 Views
14 Pages

Evaluation of Cardiovascular Disease Risk in Patients with Type 2 Diabetes Mellitus Using Clinical Laboratory Markers

  • Battamir Ulambayar,
  • Amr Sayed Ghanem,
  • Nguyen Minh Chau,
  • Eszter Vargáné Faludi,
  • Marianna Móré and
  • Attila Csaba Nagy

18 June 2024

Background: Cardiovascular diseases (CVD) are the main cause of death in the population with diabetes mellitus. This study purposed to determine clinical laboratory markers that might be correlated with the risk of CVD in individuals with type 2 diab...

  • Article
  • Open Access
15 Citations
4,852 Views
10 Pages

Relationship among Activities of Daily Living, Nutritional Status, and 90 Day Readmission in Elderly Patients with Heart Failure

  • Masahiro Kitamura,
  • Kazuhiro P. Izawa,
  • Masakazu Yaekura,
  • Yumi Mimura,
  • Yuichi Ikeda,
  • Hitomi Nagashima and
  • Peter H. Brubaker

Purpose: This investigation aimed to examine the relationship among activities of daily living (ADL), nutritional status and 90-day hospital readmission in elderly heart failure (HF) patients. Methods: Participants were selected from 634 HF patients...

  • Article
  • Open Access
7 Citations
3,372 Views
13 Pages

Association between Pre-Existing Sleep Disorders and Survival Rates of Patients with Breast Cancer

  • Yen-Chang Chen,
  • Wan-Ming Chen,
  • Ming-Feng Chiang,
  • Ben-Chang Shia and
  • Szu-Yuan Wu

4 February 2022

PURPOSE: To investigate the effects of pre-existing sleep disorders on the survival outcomes of women receiving standard treatments for breast invasive ductal carcinoma (IDC). METHODS: We recruited patients from the Taiwan Cancer Registry Database wh...

  • Article
  • Open Access
8 Citations
4,609 Views
11 Pages

29 June 2021

We opted to investigate whether a critical threshold exists for long-term pediatric neurological morbidity, and cerebral palsy (CP), in preterm delivery, via a population-based cohort analysis. Four study groups were classified according to their ges...

  • Article
  • Open Access
69 Citations
7,063 Views
11 Pages

Gonorrhea is a major global public health problem with emergence of multiple drug-resistant strains with no effective vaccine. This retrospective cohort study aimed to estimate the effectiveness of the New Zealand meningococcal B vaccine against gono...

  • Article
  • Open Access
13 Citations
2,622 Views
16 Pages

Serum Myostatin Predicts the Risk of Hepatocellular Carcinoma in Patients with Alcoholic Cirrhosis: A Multicenter Study

  • Ji Hyun Kim,
  • Seong Hee Kang,
  • Minjong Lee,
  • Gi Soo Youn,
  • Tae Suk Kim,
  • Baek Gyu Jun,
  • Moon Young Kim,
  • Young Don Kim,
  • Gab Jin Cheon and
  • Dong Joon Kim
  • + 3 authors

12 November 2020

Background and Aim: Previous studies reported that serum myostatin is associated with sarcopenia. We aimed to elucidate the association between serum myostatin levels and hepatocellular carcinoma (HCC) development in patients with alcoholic liver cir...

  • Article
  • Open Access
1,653 Views
14 Pages

Assessing First and Multiple Reoperations in 23,301 Breast Reconstructions: Immediate Versus Delayed Reconstructions in Women with Breast Cancer

  • Kathryn E. Royse,
  • Tina M. Smith,
  • Cissy M. Tan,
  • Eric Y. Lin,
  • Robert G. Neumann,
  • Jessica E. Harris,
  • Elizabeth W. Paxton and
  • Winnie M. Tong

2 April 2025

Background: Few studies have compared the risk of reoperation by timing in breast reconstruction surgery after mastectomy. We evaluated the first and total number of reoperations by reconstruction timing in women with breast cancer undergoing primary...

  • Article
  • Open Access
13 Citations
1,568 Views
5 Pages

Mortality After Femoral Neck Fractures: A Two-Year Follow-up

  • Jaunius Kurtinaitis,
  • Jolanta Dadonienė,
  • Giedrius Kvederas,
  • Narūnas Porvaneckas and
  • Tomas Butėnas

Background and Objective. To identify the survival and standardized mortality ratio with respect to gender, age, and treatment method of patients treated for femoral neck fractures. Material and Methods. A retrospective review of medical records of...

  • Article
  • Open Access
4 Citations
2,640 Views
19 Pages

The Prediction of Survival Outcome and Prognosis Factor in Association with Comorbidity Status in Patients with Colorectal Cancer: A Research-Based Study

  • Hafeez Afolabi,
  • Salzihan Md Salleh,
  • Zaidi Zakaria,
  • Ewe Seng Ch’ng,
  • Siti Norasikin Mohd Nafi,
  • Ahmad Aizat Bin Abdul Aziz,
  • Sameer Badri Al-Mhanna,
  • Yusuf Wada and
  • Abdulwali Sabo Abdulrahman

5 September 2022

Colorectal carcinoma (CRC) is rising exponentially in Asia, representing 11% of cancer worldwide. This study analysed the influence of CRC on patients’ life expectancy (survival and prognosis factors) via clinicopathology data and comorbidity s...

  • Article
  • Open Access
2 Citations
2,470 Views
12 Pages

16 December 2023

We aimed to investigate the risk factors of early double-J ureteral stent (DJUS) dysfunction rates and the long-term patency of DJUSs inserted via a percutaneous approach in patients with benign uretero-ileal anastomosis stricture (UIAS) who had unde...

  • Article
  • Open Access
20 Citations
2,748 Views
11 Pages

The Association of Minimally Invasive Surgical Approaches and Mortality in Patients with Malignant Pleuropericarditis—A 10 Year Retrospective Observational Study

  • Claudiu-Eduard Nistor,
  • Camelia Stanciu Găvan,
  • Alexandra-Andreea Ciritel,
  • Alexandra Floriana Nemes and
  • Adrian Ciuche

Background and Objectives: Malignant neoplasms are common causes of acute pleuropericardial effusion. Pleuropericarditis denotes poor patient prognosis, is associated with shortened average survival time, and represents a surgical emergency. Material...

  • Article
  • Open Access
20 Citations
4,261 Views
12 Pages

Admission Lactate Concentration, Base Excess, and Alactic Base Excess Predict the 28-Day Inward Mortality in Shock Patients

  • Piotr Smuszkiewicz,
  • Natalia Jawień,
  • Jakub Szrama,
  • Marta Lubarska,
  • Krzysztof Kusza and
  • Przemysław Guzik

18 October 2022

Base excess (BE) and lactate concentration may predict mortality in critically ill patients. However, the predictive values of alactic BE (aBE; the sum of BE and lactate), or a combination of BE and lactate are unknown. The study aimed to investigate...

  • Article
  • Open Access
4 Citations
3,862 Views
14 Pages

Development of Predictive Models for Survival among Women with Breast Cancer in Malaysia

  • Mohd Nasrullah Nik Ab Kadir,
  • Najib Majdi Yaacob,
  • Siti Norbayah Yusof,
  • Imi Sairi Ab Hadi,
  • Kamarul Imran Musa,
  • Seoparjoo Azmel Mohd Isa,
  • Balqis Bahtiar,
  • Farzaana Adam,
  • Maya Mazuwin Yahya and
  • Suhaily Mohd Hairon

Prediction of survival probabilities based on models developed by other countries has shown inconsistent findings among Malaysian patients. This study aimed to develop predictive models for survival among women with breast cancer in Malaysia. A retro...

  • Article
  • Open Access
1 Citations
3,769 Views
9 Pages

Comparison of Long-Term Pneumonia Risk between Spleen Injury and Non-Spleen Injury after Total Splenectomy—A Population-Based Study

  • Chun-Cheng Lin,
  • Sheng-Der Hsu,
  • Wu-Chien Chien,
  • Chi-Hsiang Chung,
  • Cheng-Jueng Chen,
  • Chia-Ming Liang and
  • Zhi-Jie Hong

18 February 2022

Patients who undergo splenectomy are at a high risk of infection. We aimed to investigate the rate of pneumonia in patients who underwent splenectomy, specifically comparing those who had splenectomy due to spleen injury and those who had it for othe...

  • Article
  • Open Access
6 Citations
3,751 Views
8 Pages

Accumulating evidence has shown a significant correlation between periodontal diseases and systemic diseases. In this study, we investigated the association between the frequency of tooth scaling and acute myocardial infarction (AMI). Here, a group o...

of 16