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46 Results Found

  • Article
  • Open Access
2 Citations
2,109 Views
42 Pages

30 August 2025

Background and Objectives: Cerebral microbleeds (CMBs) are increasingly being considered as potential biomarkers of small vessel disease and cerebral vulnerability, particularly in patients with acute ischemic stroke (AIS). Accurate detection is cruc...

  • Article
  • Open Access
15 Citations
3,791 Views
19 Pages

A Comprehensive Analysis of Deep Neural-Based Cerebral Microbleeds Detection System

  • Maria Anna Ferlin,
  • Michał Grochowski,
  • Arkadiusz Kwasigroch,
  • Agnieszka Mikołajczyk,
  • Edyta Szurowska,
  • Małgorzata Grzywińska and
  • Agnieszka Sabisz

9 September 2021

Machine learning-based systems are gaining interest in the field of medicine, mostly in medical imaging and diagnosis. In this paper, we address the problem of automatic cerebral microbleeds (CMB) detection in magnetic resonance images. It is challen...

  • Article
  • Open Access
8 Citations
2,565 Views
18 Pages

The anisotropies of the Stochastic Gravitational-Wave Background (SGWB), produced by merging compact binaries, constitute a possible new probe of the Large-Scale Structure (LSS). However, the significant shot noise contribution caused by the discrete...

  • Article
  • Open Access
1 Citations
2,393 Views
40 Pages

The detection of Cerebral Microbleeds (CMBs) is crucial for diagnosing cerebral small vessel disease. However, due to the small size and subtle appearance of CMBs in susceptibility-weighted imaging (SWI), manual detection is both time-consuming and l...

  • Article
  • Open Access
8 Citations
5,190 Views
12 Pages

Longitudinal Magnetic Resonance Imaging of Cerebral Microbleeds in Multiple Sclerosis Patients

  • Karthikeyan Subramanian,
  • David Utriainen,
  • Deepa P. Ramasamy,
  • Sean K. Sethi,
  • Ferdinand Schweser,
  • John Beaver,
  • Jesper Hagemeier,
  • Bianca Weinstock-Guttman,
  • Rajasimhan Rajagovindan and
  • Ewart Mark Haacke
  • + 1 author

12 November 2020

We hypothesized that cerebral microbleeds (CMBs) in multiple sclerosis (MS) patients will be detected with higher prevalence compared to healthy controls (HC) and that quantitative susceptibility mapping (QSM) will help remove false positives seen in...

  • Article
  • Open Access
230 Views
12 Pages

A Two-Stage Localization and Refinement Neural Network Structure for Data-Efficient Microbleed Detection

  • Lukas Rau,
  • Oliver Granert,
  • Nils G. Margraf,
  • Stephan Schneider and
  • Ulf Jensen-Kondering

10 February 2026

Background/Objectives: In medical diagnostics, (semi-)automatic detection of pathological structures in images is becoming increasingly important. In particular, detecting cerebral microbleeds (CMBs) poses a challenge in clinical practice because the...

  • Article
  • Open Access
12 Citations
3,175 Views
14 Pages

25 November 2021

‘Jimba’ is a white chrysanthemum cultivar, which occasionally and spontaneously produces red flower petals under natural cultivation due to cyanidin-based anthocyanin accumulation. To investigate the underlying mechanism of this process,...

  • Review
  • Open Access
2,420 Views
15 Pages

The Dark Side of Cardiac and Aortic Interventions: Unveiling Cerebral Microbleeds with Susceptibility-Weighted Imaging

  • Tommaso Casseri,
  • Maria Giulia Maccaglia,
  • Ivano Lombardo,
  • Andrea Bianchi,
  • Rosaria Tartarone,
  • Giorgio Busto,
  • Andrea Ginestroni,
  • Sara Speziali,
  • Walter Dorigo and
  • Enrico Fainardi

Cerebral microbleeds (CMBs) are increasingly detected in patients with aortic and cardiac diseases following transcatheter aortic valve implantation (TAVI), thoracic endovascular aortic repair (TEVAR), or cardiac surgery. CMBs can be observed in magn...

  • Article
  • Open Access
6 Citations
5,335 Views
11 Pages

Status of Cosmic Microwave Background Observations for the Search of Primordial Gravitational Waves

  • Elia Stefano Battistelli,
  • Valentina Capalbo,
  • Giovanni Isopi and
  • Federico Radiconi

15 September 2022

The cosmic microwave background (CMB) is one of the most powerful tools for cosmology. Its polarization could have imprinted the sign of an inflationary background of gravitational waves, which is supposed to have originated at 1038/103...

  • Article
  • Open Access
25 Citations
4,649 Views
12 Pages

Hydrogen peroxide (H2O2) plays an important role in the human body and monitoring its level is meaningful due to the relationship between its level and diseases. A fluorescent sensor (CMB) based on coumarin was designed and its ability for detecting...

  • Brief Report
  • Open Access
1,031 Views
8 Pages

10 August 2025

Introduction: It has been recently demonstrated that some cerebral microbleeds (CMBs) are connected to cerebral veins in patients with cerebral small vessel disease (CSVD) including cerebral amyloid angiopathy (CAA). We sought to demonstrate the pres...

  • Article
  • Open Access
3 Citations
4,629 Views
6 Pages

Can CMB Surveys Help the AGN Community?

  • Bruce Partridge,
  • Laura Bonavera,
  • Marcos López-Caniego,
  • Rahul Datta,
  • Joaquin Gonzalez-Nuevo,
  • Megan Gralla,
  • Diego Herranz,
  • Anne Lähteenmäki,
  • Laura Mocanu and
  • Lizhong Zhang
  • + 3 authors

30 August 2017

Contemporary projects to measure anisotropies in the cosmic microwave background (CMB) are now detecting hundreds to thousands of extragalactic radio sources, most of them blazars. As a member of a group of CMB scientists involved in the construction...

  • Article
  • Open Access
12 Citations
3,190 Views
9 Pages

Prospective Assessment of Cerebral Microbleeds with Low-Field Magnetic Resonance Imaging (0.55 Tesla MRI)

  • Thilo Rusche,
  • Hanns-Christian Breit,
  • Michael Bach,
  • Jakob Wasserthal,
  • Julian Gehweiler,
  • Sebastian Manneck,
  • Johanna M. Lieb,
  • Gian Marco De Marchis,
  • Marios Psychogios and
  • Peter B. Sporns

2 February 2023

Purpose: Accurate detection of cerebral microbleeds (CMBs) on susceptibility-weighted (SWI) magnetic resonance imaging (MRI) is crucial for the characterization of many neurological diseases. Low-field MRI offers greater access at lower costs and low...

  • Article
  • Open Access
81 Views
12 Pages

The Role of Leukoaraiosis and Microbleeds in Acute Ischemic Stroke Outcome Prediction

  • Aleksandra Aracki-Trenkic,
  • Dunja Radovanović,
  • Bruno Law-ye,
  • Didier Dormont,
  • Nadya Pyatigorskaya and
  • Milica Živanović

1 March 2026

Background/Objectives: Acute ischemic stroke (AIS) is one of the leading causes of mortality worldwide and the primary cause of acquired neurological disability in adults. As part of a stroke magnetic resonance (MR) protocol, fluid-attenuated inversi...

  • Article
  • Open Access
3 Citations
2,683 Views
12 Pages

26 September 2023

This paper proposes two max-pooling engines, named the RTB-MAXP engine and the CMB-MAXP engine, with a scalable window size parameter for FPGA-based convolutional neural network (CNN) implementation. The max-pooling operation for the CNN can be decom...

  • Feature Paper
  • Article
  • Open Access
22 Citations
6,130 Views
17 Pages

16 August 2019

Chemical analysis of a cultivation of an Australian Mugil mullet gastrointestinal tract (GIT) derived fungus, Scopulariopsis sp. CMB-F458, yielded the known lipodepsipeptides scopularides A (1) and B (2). A comparative global natural product social (...

  • Article
  • Open Access
2 Citations
2,884 Views
32 Pages

Quantum Non-Locality and the CMB: What Experiments Say

  • Maurizio Consoli,
  • Alessandro Pluchino and
  • Paola Zizzi

13 September 2022

“Non-locality is most naturally incorporated into a theory in which there is a special frame of reference. One possible candidate for this special frame of reference is the one in which the Cosmic Microwave Background (CMB) is isotropic. Howeve...

  • Article
  • Open Access
3 Citations
1,949 Views
14 Pages

Optimization of a Microwave Polarimeter for Astronomy with Optical Correlation and Detection

  • Guillermo Pascual-Cisneros,
  • Francisco J. Casas and
  • Patricio Vielva

22 February 2023

Cosmic Microwave Background (CMB) B-modes detection is the main focus of future CMB experiments because of the valuable information it contains, particularly to probe the physics of the very early universe. For this reason, we have developed an optim...

  • Article
  • Open Access
4 Citations
2,515 Views
16 Pages

Polarization Calibration of a Microwave Polarimeter with Near-Infrared Up-Conversion for Optical Correlation and Detection

  • Francisco J. Casas,
  • Patricio Vielva,
  • R. Belen Barreiro,
  • Enrique Martínez-González and
  • G. Pascual-Cisneros

21 October 2022

This paper presents a polarization calibration method applied to a microwave polarimeter demonstrator based on a near-infrared (NIR) frequency up-conversion stage that allows both optical correlation and signal detection at a wavelength of 1550 nm. T...

  • Article
  • Open Access
17 Citations
5,047 Views

Recent Progress in Understanding the Large Scale Jets of Powerful Quasars

  • Markos Georganopoulos,
  • Eileen T. Meyer and
  • Eric S. Perlman

23 November 2016

Our understanding of the physics of kpc-scale quasar jets had seemed to converge to a paradigm in which these jets are as highly relativistic on the kpc scale as they are on sub-pc scales close to the central black hole. Retaining bulk Lorentz factor...

  • Article
  • Open Access
7 Citations
1,681 Views
13 Pages

26 July 2024

bZIP transcription factors play important roles in regulating plant development and stress responses. Although bZIPs have been identified in many plant species, there is little information on the bZIPs in Chrysanthemum. In this study, bZIP TFs were i...

  • Review
  • Open Access
9 Citations
2,613 Views
19 Pages

Neutrino at Different Epochs of the Friedmann Universe

  • Alexandre V. Ivanchik,
  • Oleg A. Kurichin and
  • Vlad Yu. Yurchenko

2 April 2024

At least two relics of the Big Bang have survived: the cosmological microwave background (CMB) and the cosmological neutrino background (CνB). Being the second most abundant particle in the universe, the neutrino has a significant impact on its ev...

  • Article
  • Open Access
7 Citations
2,672 Views
13 Pages

25 November 2021

The ethyl acetate extract of an ISP-2 agar cultivation of the wasp nest-associated fungus Penicillium sp. CMB-MD14 exhibited promising antibacterial activity against vancomycin-resistant enterococci (VRE), with a bioassay guided chemical investigatio...

  • Article
  • Open Access
9 Citations
3,979 Views
18 Pages

A library of fungi previously recovered from the gastrointestinal tract (GIT) of several fresh, commercially sourced Australian mullet fish was re-profiled for production of a rare class of phenylpropanoid piperazine alkaloids (chrysosporazines) usin...

  • Article
  • Open Access
3 Citations
3,978 Views
6 Pages

15 November 2016

The LBL AP Librae has been detected in the TeV gamma-ray range, which is unexpected for this kind of blazar. The broad-band SED cannot be explained by a one-zone model, and especially fails in the TeV domain. An extended jet has been detected on arcs...

  • Communication
  • Open Access
1 Citations
10,444 Views
5 Pages

Many totally different kinds of astrophysical observations demonstrated that, in our universe, there exists a preferred direction. Specifically, from observations in a wide range of frequencies, the alignment of various preferred directions in differ...

  • Article
  • Open Access
23 Citations
5,520 Views
16 Pages

Impact of Cerebral Amyloid Angiopathy in Two Transgenic Mouse Models of Cerebral β-Amyloidosis: A Neuropathological Study

  • Paula Marazuela,
  • Berta Paez-Montserrat,
  • Anna Bonaterra-Pastra,
  • Montse Solé and
  • Mar Hernández-Guillamon

The pathological accumulation of parenchymal and vascular amyloid-beta (Aβ) are the main hallmarks of Alzheimer’s disease (AD) and Cerebral Amyloid Angiopathy (CAA), respectively. Emerging evidence raises an important contribution of vascu...

  • Article
  • Open Access
1,330 Views
21 Pages

Groundwater Recharge Estimation Based on Environmental Isotopes, Chloride Mass Balance and SWAT Model in Arid Lands, Southwestern Saudi Arabia

  • Milad Masoud,
  • Maged El Osta,
  • Jalal Basahi,
  • Burhan Niyazi,
  • Nassir Al-Amri,
  • Michael Schneider,
  • Abdulaziz Alqarawy and
  • Riyadh Halawani

16 November 2025

Estimated groundwater recharge is considered the essential factor for groundwater management and sustainability, especially in arid lands such as the Kingdom of Saudi Arabia (KSA). Consequently, assessing groundwater recharge is a key process for for...

  • Article
  • Open Access
1 Citations
1,842 Views
12 Pages

Molecular Diversity and Distribution of Whiteflies (Bemisia tabaci) in Cassava Fields Across South West and North Central, Nigeria

  • Oghenevwairhe P. Efekemo,
  • Olabode A. Onile-ere,
  • Isaac O. Abegunde,
  • Folashade T. Otitolaye,
  • Justin S. Pita,
  • Titus Alicai and
  • Angela O. Eni

20 November 2024

Whitefly Bemisia tabaci (Gennadium, Hemiptera) causes severe damage to cassava plants through excessive feeding on leaves and transmitting viruses, such as African cassava mosaic virus (ACMV), East African cassava mosaic virus (EACMV), and ipomovirus...

  • Article
  • Open Access
7 Citations
3,723 Views
16 Pages

7 November 2022

Analytical scale chemical/cultivation profiling prioritized the Australian marine-derived fungus Aspergillus noonimiae CMB-M0339. Subsequent investigation permitted isolation of noonindoles A–F (510) and detection of eight minor analogue...

  • Article
  • Open Access
3 Citations
2,791 Views
17 Pages

19 December 2022

This study showcases the application of an integrated workflow of molecular networking chemical profiling (GNPS), together with miniaturized microbioreactor cultivation profiling (MATRIX) to successfully detect, dereplicate, prioritize, optimize the...

  • Feature Paper
  • Review
  • Open Access
26 Citations
7,761 Views
16 Pages

Development of the Troponin Detection System Based on the Nanostructure

  • Taek Lee,
  • Jae-Hyuk Ahn,
  • Jinha Choi,
  • Yeonju Lee,
  • Jin-Myung Kim,
  • Chulhwan Park,
  • Hongje Jang,
  • Tae-Hyung Kim and
  • Min-Ho Lee

22 March 2019

During the last 30 years, the World Health Organization (WHO) reported a gradual increase in the number of patients with cardiovascular disease (CVD), not only in developed but also in developing countries. In particular, acute myocardial infarction...

  • Article
  • Open Access
3 Citations
2,361 Views
29 Pages

13 October 2025

Background/Objectives: Cerebral small vessel disease (CSVD) is a leading cause of cognitive decline and dementia. The comparative prognostic value of MRI-based neuroimaging markers and genetic risk factors such as the APOE ε4 allele for cogni...

  • Article
  • Open Access
11 Citations
3,754 Views
18 Pages

Epidemiological Analysis of Cassava Mosaic and Brown Streak Diseases, and Bemisia tabaci in the Comoros Islands

  • Rudolph Rufini Shirima,
  • Everlyne Nafula Wosula,
  • Abdou Azali Hamza,
  • Nobataine Ali Mohammed,
  • Hadji Mouigni,
  • Salima Nouhou,
  • Naima Mmadi Mchinda,
  • Gloria Ceasar,
  • Massoud Amour and
  • James Peter Legg
  • + 1 author

30 September 2022

A comprehensive assessment of cassava brown streak disease (CBSD) and cassava mosaic disease (CMD) was carried out in Comoros where cassava yield (5.7 t/ha) is significantly below the African average (8.6 t/ha) largely due to virus diseases. Observat...

  • Letter
  • Open Access
14 Citations
5,587 Views
9 Pages

GRACE—Gravity Data for Understanding the Deep Earth’s Interior

  • Mioara Mandea,
  • Véronique Dehant and
  • Anny Cazenave

21 December 2020

While the main causes of the temporal gravity variations observed by the Gravity Recovery and Climate Experiment (GRACE) space mission result from water mass redistributions occurring at the surface of the Earth in response to climatic and anthropoge...

  • Article
  • Open Access
2 Citations
1,896 Views
13 Pages

11 July 2023

This paper presents a study of the performances of different Mach–Zehnder modulation technologies with applications in microwave polarimeters based on a near-infrared (NIR) frequency up-conversion stage, allowing for optical correlation and sig...

  • Article
  • Open Access
8 Citations
4,422 Views
25 Pages

2 June 2023

Despite over a century of research, the physics of galaxy rotation is not yet fully understood, and there is a clear discrepancy between the observed mass of galaxies and their rotational velocity. Here, we report on another observation of tension be...

  • Article
  • Open Access
14 Citations
4,120 Views
14 Pages

12 March 2021

Further investigation into a fish gut-derived fungus Evlachovaea sp. CMB-F563, previously reported to produce the unprecedented Schiff base prolinimines A–B (12), revealed a new cryptic natural product, N-amino-l-proline methyl ester (5)—only the se...

  • Article
  • Open Access
15 Citations
2,964 Views
13 Pages

Observational Constraints on F(T,TG) Gravity with Hubble’s Parametrization

  • Salim Harun Shekh,
  • Nurgissa Myrzakulov,
  • Anirudh Pradhan and
  • Assem Mussatayeva

23 January 2023

Any new gravitational theories can be built with the help of a gauge theory with local Poincare symmetry. This local Poincare symmetry can set up a space-time with torsion. In the present study, the authors working on the parametrization approach tow...

  • Article
  • Open Access
4 Citations
2,130 Views
16 Pages

4 February 2024

The Hubble tension in cosmology is not showing signs of alleviation and thus, it is important to look for alternative approaches to it. One such example would be the eventual detection of a time delay between simultaneously emitted high-energy and lo...

  • Article
  • Open Access
17 Citations
2,700 Views
19 Pages

Integrated Metabolomics and Transcriptomics Reveal the Key Role of Flavonoids in the Cold Tolerance of Chrysanthemum

  • Di Wu,
  • Yingxue Wu,
  • Ruiqi Gao,
  • Yanhong Zhang,
  • Ruiying Zheng,
  • Minghui Fang,
  • Yuhua Li,
  • Yang Zhang,
  • Le Guan and
  • Yanqiang Gao

Chrysanthemum (Chrysanthemum morifolium, ground-cover Chrysanthemums), one of the important garden flowers, has a high ornamental and economic value. However, its ornamental value is significantly diminished by the low temperature experienced in nort...

  • Article
  • Open Access
11 Citations
4,025 Views
17 Pages

23 January 2021

Wildfire occurrence and severity in the Mediterranean region during the summer season is increasing, being favoured by climate change-induced conditions (i.e., drought, heatwaves). Moreover, additional natural sources frequently impact this region, p...

  • Article
  • Open Access
8 Citations
5,854 Views
12 Pages

The Pierre Auger Observatory: Review of Latest Results and Perspectives

  • Dariusz Góra and
  • For the Pierre Auger Collaboration

17 November 2018

The Pierre Auger Observatory is the world’s largest operating detection system for the observation of ultra high energy cosmic rays (UHECRs), with energies above 10 17 eV. The detector allows detailed measurements of the energy spectrum, mass...

  • Article
  • Open Access
8 Citations
2,464 Views
21 Pages

Constraining the Initial Mass Function in the Epoch of Reionization from Astrophysical and Cosmological Data

  • Andrea Lapi,
  • Giovanni Gandolfi,
  • Lumen Boco,
  • Francesco Gabrielli,
  • Marcella Massardi,
  • Balakrishna S. Haridasu,
  • Carlo Baccigalupi,
  • Alessandro Bressan and
  • Luigi Danese

13 March 2024

We aim to constrain the stellar initial mass function (IMF) during the epoch of reionization. To this purpose, we build up a semi-empirical model for the reionization history of the Universe based on various ingredients: the latest determination of t...

  • Article
  • Open Access
2 Citations
2,015 Views
23 Pages

Quark Clusters, QCD Vacuum and the Cosmological 7Li, Dark Matter and Dark Energy Problems

  • Rachid Ouyed,
  • Denis Leahy,
  • Nico Koning and
  • Prashanth Jaikumar

1 March 2024

We propose a non-exotic electromagnetic solution (within the standard model of particle physics) to the cosmological 7Li problem based upon a narrow 2 MeV photo-emission line from the decay of light glueballs (LGBs). These LGBs form within color supe...