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The COVID-19 pandemic demonstrated that vulnerability, rather than chronological age alone, is a major determinant of severe infectious-disease outcomes; yet adult vaccination policies remain largely based on age and selected medical conditions. This...

Influenza infection is increasingly recognized as an important cardiovascular risk factor beyond its traditional role as a respiratory illness. Influenza infection may precipitate myocardial infarction, stroke, heart failure exacerbation, and arrhyth...

This study investigated the prevalence of burnout and the level of work engagement, as well as their associated factors, among care workers (CWs) in Japanese long-term care (LTC) hospitals. This Cross-sectional questionnaire survey was conducted in L...

Dementia has traditionally been regarded as one of the most feared, and least modifiable, consequences of ageing [...]

Population aging currently represents a crucial challenge, making prevention a fundamental pillar in managing expenditures for global healthcare systems. Among these preventive measures, vaccination certainly stands out as a cornerstone of both preve...

Older adults with chronic obstructive pulmonary disease (COPD) are particularly vulnerable to respiratory infections because of reduced pulmonary reserve, comorbidity, and age-related changes in immune function. This narrative review examines the rol...

Modern public health strategies are undergoing fundamental shifts as global populations age, and vaccination is on the front lines, transitioning from a traditional focus on the pediatric immunization model to a “life-course” vaccination...

Evidence regarding endoscopic retrograde cholangiopancreatography (ERCP) in adults in their 90s and 100s remains limited, and chronological age may not adequately reflect procedural vulnerability. We compared ERCP strategy and short-term outcomes acr...

With limited bed availability at Malta’s state-run rehabilitation hospital, efficient and accurate assessment of frail older adults is essential for appropriate inpatient geriatric rehabilitation (GR) admissions. This study aimed to identify ke...

Older adults may have both someone to consult and opportunities to be consulted by family or friends. This cross-sectional secondary analysis examined their mutually adjusted associations with happiness and self-rated health using a nationwide survey...

Dementia is a global burden for patients, families and healthcare systems. Approximately 45% of dementia cases may potentially be prevented or delayed by acting on modifiable risk factors, but current prevention initiatives might not be effective in...

Lower respiratory infections remain the leading infectious cause of death worldwide, with pneumonia causing a substantial burden of morbidity, mortality, and long-term complications in older adults, particularly among those with chronic comorbidities...

Psychological sweating in the palms occurs in response to mental activity. This sweating response (SR) may be observed during concentrated finger perception and may be associated with tactile sensitivity in older adults. This research was conducted a...

Ambient temperature has been associated with daily step counts, but evidence characterizing continuous, non-linear relationships in older adults remains limited, particularly in large cohorts with repeated daily measurements. This study examined the...

Physical exercise is considered an effective and relatively safe practice to reduce or control levels of pro-inflammatory mediators during aging. However, findings are often interpreted primarily through statistical significance, while the magnitude...

Sarcopenia is a progressive skeletal muscle disorder in which clinically relevant muscle failure is expressed primarily as reduced muscle strength, with low muscle quantity or quality used to confirm the diagnosis and impaired physical performance in...

Chronic non-cancer pain (CNCP) is a complex and highly prevalent condition among older adults that contributes to suffering and disability. It is frequently underestimated and normalized as part of aging. This scoping review aimed to identify and des...

UK cancer waiting-time standards inadequately address the complex needs of older patients, and no standardised, implementable comprehensive geriatric assessment (CGA) case-finding framework exists for this population. Using a nominal group technique...

Frailty is common among older adults with type 2 diabetes mellitus (T2DM). However, simple, objective, equipment-free screening tools for early frailty detection are limited. We evaluated the association between the objective one-leg standing test (O...

Built and ambient features of hospital ward design may influence patient safety and inform future hospital construction and refurbishment. However, evidence on their overall impact remains fragmented. This review synthesised available evidence and hi...

Subjective grip strength and subjective walking speed may reflect actual grip strength and walking speed, respectively, in older adults. We examined whether pre-frailty could be identified using subjective motor ability. This cross-sectional observat...

The aim of this study was to evaluate short-term outcomes and safety of elobixibat in home-care patients with chronic constipation (CC) and explore the changes in caregiver burden related to bowel management. This multicenter prospective observationa...

The longitudinal impact of fine particulate matter (PM_2.5) and its specific chemical drivers on multi-system physiological dysregulation, quantified by the allostatic load index (ALI), remains unclear. Leveraging panel data from 7421 middle-aged and...

Dance and reminiscence have each demonstrated positive outcomes in adults with dementia, yet few studies have examined their combined effects on apathy, particularly older male veterans. This pilot study investigated the preliminary effects of a seat...

Sensory and motor impairments have been independently associated with cognitive decline in older adults. However, less is known about the association between combined sensory and motor impairments and mild cognitive impairment (MCI). This study inves...

Autoimmune diseases comprise a broad group of conditions that affect virtually any organ or tissue and share mechanisms of chronic, autoimmune-based inflammation. Once rare or unknown, they have become increasingly common in recent years, affecting i...

The study examined how multiple dimensions of food access relate to frailty among community-dwelling older adults. A mail-based questionnaire was sent in August 2020 to 5000 residents aged 65 years or older in City N, Prefecture H, yielding 2151 vali...

As women age—especially after menopause—the risk of atherosclerosis increases significantly, but its physiological mechanism is still unclear. To explore potential strategies for preventing and treating postmenopausal atherosclerosis in w...

Heart failure (HF)—a highly prevalent condition among older adults—is characterized by recurrent exacerbations and progressive symptom burden, significantly affecting functional autonomy and quality of life. Palliative care may alleviate...

The coexistence of obesity, osteoporosis, and sarcopenia has been associated with adverse outcomes such as risk of falls, fractures, immobility, disability and frailty, yet data from Latin American populations are scarce. This study aimed to determin...

Sarcopenia, characterized by progressive loss of muscle mass and function, is highly prevalent among patients with heart failure (HF) and contributes to frailty, disability, and poor prognosis. Shared mechanisms—chronic inflammation, neurohormo...

Neuropsychiatric symptoms in dementia impact diagnosis and caregiver burden. Informal caregivers effectively identify cognitive changes and confirm the care receiver’s symptoms. This study aims to examine the association between neuropsychiatri...

Diabetes complications may increase frailty rates among the elderly, leading to falls, immobility, dependency, hospitalizations, and death. The study aimed to assess any association between frailty status and glycaemic control among older adults with...

Cardiovascular diseases (CVDs) are the leading cause of mortality in Italy. This study aims to describe the setting of death of patients dying from cardiovascular diseases in Italy and to explore potential changes during the COVID-19 pandemic (years...

Frailty is a highly prevalent and adverse syndrome among older adults, and there are many different assessments for screening both frailty (robust + pre-frail vs. frail) and frailty process (robust vs. pre-frail + frail). Previous studies have sugges...

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The objective was to expand community-based dementia screening across diverse settings in Brunei and evaluate the prevalence of risk factors, cognitive symptoms and factors associated with suspected cognitive impairment using the Mini-COG. Cross-sect...

Japan is a super-aged society where community group multicomponent exercise is widely implemented, yet the age at which a fixed, low-frequency exercise dose no longer offsets functional decline is unclear. We examined 6-year trainability and explored...

In the context of research aimed at identifying the causes of the progressive decline in cellular and tissue functions characteristic of aging, in recent decades, increasing attention has been devoted to the sirtuin family. Sirtuins are named after t...

The objective was to evaluate the impact of a 3-month comprehensive rehabilitation program on functional outcomes and caregiver burden in a 73-year-old male with end-stage Parkinson’s disease (PD) following pallidotomy. Baseline evaluation incl...

Dementia has a significant impact on individuals, families, communities, and the economy. Alzheimer’s disease (AD) accounts for 60–80% of dementia cases. The APOE e4 allele is well known as the primary genetic risk factor for AD and demen...

This review examines the impact of physical exercises on fluid intelligence (FI) among elderly individuals with or without dementia. Fluid intelligence declines with age and worsens faster with dementia, and studies suggest that physical exercise, li...

The Journal of Gerontology and Geriatrics (JGG) (ISSN: 2499-6564) [...]

Dear colleagues, researchers, and members of the gerontological and geriatric community, [...]

Iron deficiency (ID) is highly prevalent in older adults and remains frequently underdiagnosed despite its relevant prognostic impact. ID may be absolute or functional and is observed across multiple geriatric clinical settings, including heart failu...

Loneliness is a significant psychosocial issue among middle-aged and older adults, negatively impacting quality of life (QoL). However, little is known about how different health measures – specifically objective (multimorbidity) and subjective (self...

Physical inactivity in older adults is associated with decreased mobility, functional decline, and reduced quality of life. Music may enhance exercise engagement and adherence. This pilot randomized controlled trial evaluated the feasibility of a mus...

To analyze the effects of multicomponent exercises on muscle strength and balance in frail older individuals. This systematic review and meta-analysis followed the PRISMA criteria. The databases used were MEDLINE (via PubMed), SPORTDiscus, Web of Sci...

To conduct a systematic review of the current literature on products used in preventing and managing skin problems in individuals diagnosed with fecal incontinence. The Medline Complete, Cochrane Library, Ovid, Google Scholar, PubMed, Scopus, Science...

Myiasis, derived from the Greek “myia” (fly) and “iasis” (disease), refers to infestation by dipterous larvae. First coined by Hope in 1840 and later defined by Zumpt, myiasis involves larvae feeding on live or necrotic tissues. Oral myiasis, a rare...