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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Challenges and Advancements in Lateral Skull Base Surgery
edited by Alessia Rubini
submission deadline 30 Jul 2025 | 1 articles | Viewed by 548 | Submission Open
Keywords: lateral skull base; neurotology; jugular foramen; cerebellopontine angle; petrous apex; inner ear; acoustic neuroma; jugular paraganglioma; transtemporal approaches; infratemporal approaches
(This special issue belongs to the Section Otolaryngology)
Clinical Advances of Glaucoma: Current Status and Prospects
edited by Rubén Sánchez-Jean, and Federico Sáenz-Francés San Baldomero
submission deadline 30 Jul 2025 | Viewed by 196 | Submission Open
Keywords: glaucoma surgery; new techniques; minimally invasive glaucoma surgery; intraocular pressure; optometry; IOLs designs
(This special issue belongs to the Section Ophthalmology)
Clinical New Insights into Management of Scoliosis
edited by Piotr Janusz and Marcin Tyrakowski
submission deadline 30 Jul 2025 | Viewed by 181 | Submission Open
Keywords: scoliosis; idiopathic scoliosis; congenital scoliosis; neuromuscular scoliosis; degenerative scoliosis; kyphosis; spine deformation; scoliosis etiology; surgical treatment; non-surgical treatment
(This special issue belongs to the Section Orthopedics)
Metabolic Dysregulation Across the Spectrum from Anorexia Nervosa to Obesity
edited by Andriana C. Kaliora
submission deadline 30 Jul 2025 | Viewed by 175 | Submission Open
Keywords: metabolic dysregulation; anorexia nervosa; obesity; environmental factors in metabolic health; gut microbiota and metabolism; hormonal regulation of appetite; inflammation and metabolic disorders; dietary influence on metabolism
(This special issue belongs to the Section Endocrinology & Metabolism)
Advances in the Treatment of Glaucoma and Ocular Hypertension
edited by Ahnul Ha
submission deadline 30 Jul 2025 | Viewed by 125 | Submission Open
Keywords: glaucoma; ocular hypertension; intraocular pressure (IOP); minimally invasive glaucoma surgery (MIGS); artificial intelligence (AI); neuroprotection; meta-analysis
(This special issue belongs to the Section Ophthalmology)
Clinical Updates in Bleeding and Thrombotic Disorders
edited by
submission deadline 30 Jul 2025 | Viewed by 95 | Submission Open
Keywords: autoimmune-acquired coagulation deficiency; acquired hemophilia A; disseminated intravascular coagulation; thrombotic microangiopathy; venous thromboembolism; acute coronary syndrome; clot waveform analysis; thrombin generation test; thromboelastogram
(This special issue belongs to the Section Hematology)
The Current Trend in the Management of Bruxism and Temporomandibular Disorders submission deadline 31 Jul 2025 | 5 articles | Viewed by 16059 | Submission Open
Keywords: bruxism; temporomandibular disorders (TMDs); dental health; treatment modalities; diagnosis; clinical interventions
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Rheumatoid Arthritis: Clinical Updates on Diagnosis and Treatment
edited by
submission deadline 31 Jul 2025 | 9 articles | Viewed by 12513 | Submission Open
Keywords: rheumatoid arthritis; disease-modifying antirheumatic drugs (DMARDs); biological therapies; Janus kinase inhibitors (JAK inhibitors); treatment strategies; joint destruction; comorbidity; drug safety
(This special issue belongs to the Section Immunology)
Autoimmune-Induced Alopecia and Emerging Therapies in Hair Loss
edited by David Saceda-Corralo
submission deadline 31 Jul 2025 | 5 articles | Viewed by 12209 | Submission Open
Keywords: autoimmune-induced alopecia; alopecia areata; cicatricial alopecia; occurs; hair loss
(This special issue belongs to the Section Dermatology)
New Clinical Advances in Psoriasis and Psoriatic Arthritis
edited by and Alessandra Narcisi
submission deadline 31 Jul 2025 | 6 articles | Viewed by 11178 | Submission Open
Keywords: psoriasis; psoriatic arthritis; inflammatory skin disease; inflammatory autoimmune disease; immunotherapy; autoimmunity; comorbidities; therapeutic; diagnosis; treatment; management; biologics
(This special issue belongs to the Section Dermatology)
Clinical Advances and Challenges in Vascular and Endovascular Medicine
edited by Luca Bertoglio
submission deadline 31 Jul 2025 | 7 articles | Viewed by 9096 | Submission Open
Keywords: vascular and endovascular medicine; minimally invasive cardiovascular surgery; vascular diseases; endovascular technologies; endovascular surgery; aortic dissection
(This special issue belongs to the Section Vascular Medicine)
Physical Therapy in Neurorehabilitation
edited by Marianna Papadopoulou and
submission deadline 31 Jul 2025 | 6 articles | Viewed by 8902 | Submission Open
Keywords: physical therapy; transcutaneous electrical nerve stimulation (TENS); muscle strengthening; balance exercising; pain; quality of life; neurodegenerative disorders; neuromuscular disorders; stroke; demyelinating disorders
(This special issue belongs to the Section Clinical Neurology)
Vascular Surgery: Current Status and Future Perspectives
edited by Murray L. Shames and Adam Tanious
submission deadline 31 Jul 2025 | 4 articles | Viewed by 8710 | Submission Open
Keywords: vascular history; peripheral arterial disease; aortic aneurysm; aortic dissection; carotid disease
(This special issue belongs to the Section Vascular Medicine)
Acute Respiratory Failure: Innovations and Clinical Insights
edited by
submission deadline 31 Jul 2025 | 3 articles | Viewed by 8487 | Submission Open
Keywords: ARF; mechanical ventilation; VILI; PSILI; NIV; HFNO; weaning; EIT; lung US
(This special issue belongs to the Section Intensive Care)
Endoscopic Techniques in Digestive and Gynecological Diseases
edited by , Teresa Mascarenhas and
submission deadline 31 Jul 2025 | 3 articles | Viewed by 7099 | Submission Open
Keywords: endoscopy; gastroenterology; gynecology; colonoscopy; colposcopy; artificial intelligence; capsule endoscopy; upper endoscopy; hysteroscopy; pancreatobiliary endoscopy
(This special issue belongs to the Section General Surgery)
Oral and Maxillofacial Surgery: Current Updates and Perspectives submission deadline 31 Jul 2025 | 5 articles | Viewed by 6727 | Submission Open
Keywords: current updates in oral and maxillofacial surgery; new insights in oral medicine; advances in dental implantology; 3D pre-surgical evaluation in oral and maxillofacial surgery; regenerative dentistry
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Orthopedic Surgery: Latest Advances and Future Prospects
edited by Andrea Marinozzi and
submission deadline 31 Jul 2025 | 4 articles | Viewed by 6694 | Submission Open
Keywords: custom-made; regenerative; prosthetic; noninvasive surgery; robotic surgery; percutaneous surgery; minimally invasive surgery
(This special issue belongs to the Section Orthopedics)
Clinical Advances in Endoscopic Ultrasound-Guided Diagnosis and Treatment
edited by Nicola Muscatiello
submission deadline 31 Jul 2025 | 3 articles | Viewed by 6618 | Submission Open
Keywords: endoscopic ultrasound (EUS); pancreas; cancer; lumen apposing metal stent (LAMS); stent
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Emerging Treatment Options for Skull Base Tumors and Related Diseases
edited by
submission deadline 31 Jul 2025 | 4 articles | Viewed by 4726 | Submission Open
Keywords: neurosurgery; skull base tumors; minimally invasive approaches; neuro-oncology; endoscopic endonasal surgery
(This special issue belongs to the Section Oncology)
Clinical Advances in Reconstructive Surgery: Innovations and Outcomes for Improved Patient Care
edited by Rami S. Kantar
submission deadline 31 Jul 2025 | 4 articles | Viewed by 4366 | Submission Open
Keywords: reconstructive surgery; clinical advances; innovations; surgical outcomes; patient care; cleft lip repair; breast reconstruction; facial reconstruction; hand surgery; burn reconstruction; minimally invasive procedures; patient-specific treatment planning; anesthesia and pain management; regenerative medicine
(This special issue belongs to the Section General Surgery)
Clinical Advances in Cardiothoracic Anesthesia
edited by Eleni Arnaoutoglou and Metaxia V. Bareka
submission deadline 31 Jul 2025 | 5 articles | Viewed by 4047 | Submission Open
Keywords: cardiac anesthesia; perioperative medicine; outcome; regional anesthesia; novel pharmacological agents; minimally invasive surgical methods; enhanced recovery; patient safety
(This special issue belongs to the Section Anesthesiology)
Advances in the Diagnosis, Treatment, and Prognosis of Aortic Stenosis
edited by Rita Milewski
submission deadline 31 Jul 2025 | 3 articles | Viewed by 3740 | Submission Open
Keywords: aortic valve stenosis; aortic valve replacement; surgical aortic valve replacement; transfemoral aortic valve replacement; risk stratification for aortic stenosis
(This special issue belongs to the Section Cardiology)
Current Challenges in Clinical Dentistry: 2nd Edition
edited by and
submission deadline 31 Jul 2025 | 2 articles | Viewed by 3271 | Submission Open
Keywords: AI; clinical dentistry; epidemiology; geriatric dentistry; dental technology; dental material; challenging hypothesis; preventive dentistry; sleep medicine; digital dentistry; smart dentistry; stomatognathic function
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Female Infertility: Clinical Diagnosis and Treatment
edited by
submission deadline 31 Jul 2025 | 4 articles | Viewed by 2994 | Submission Open
Keywords: infertility; assisted reproductive techniques; diagnosis; implantation; gametes
(This special issue belongs to the Section Obstetrics & Gynecology)
Recent Advances in Minimally Invasive Gynecologic Surgery (MIGS)
edited by Laurenţiu Cornel Pirtea, and Răzvan Ciortea
submission deadline 31 Jul 2025 | 3 articles | Viewed by 2957 | Submission Open
Keywords: laparoscopy; urogynecology; oncologic surgery; minimally invasive surgery
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Updates on Perioperative Pain Management: 2nd Edition submission deadline 31 Jul 2025 | 4 articles | Viewed by 2713 | Submission Open
Keywords: anesthesia and intensive care; pain management; spinal anesthesia; postoperative pain; breast surgery; fascial plane blocks; abdominal surgery; cardiac surgery; thoracotomy; knee surgery; orthopedic surgery; hip surgery; ultrasound
(This special issue belongs to the Section Anesthesiology)
Personalized Medicine for the Management of Non-Communicable Disease (NCDs)
edited by , Giulio Geraci and
submission deadline 31 Jul 2025 | 3 articles | Viewed by 2377 | Submission Open
Keywords: personalized medicine; precision medicine; non-communicable disease; cardiovascular disease; cancer; diabetes; chronic obstructive pulmonary disease; cognitive impairment; atherosclerosis; lipids; inflammation; immunity; therapy
(This special issue belongs to the Section Epidemiology & Public Health)
Advanced Strategies and Innovations to Enhance Outcomes in Cardiac Ablation submission deadline 31 Jul 2025 | 3 articles | Viewed by 2377 | Submission Open
Keywords: arrhythmias; cardiac ablation; catheter technology; imaging; anticoagulation optimization; post-procedure care
(This special issue belongs to the Section Cardiology)
Challenges in Minimally Invasive Colorectal and Abdominal Wall Surgery
edited by Francesco Ferrara and
submission deadline 31 Jul 2025 | 2 articles | Viewed by 2220 | Submission Open
Keywords: colorectal surgery; laparoscopy; abdominal wall surgery; hernia; diastasis recti; surgical oncology; rectal tumor; colon tumor; colorectal neoplasia
(This special issue belongs to the Section General Surgery)
Cardiac Sarcoidosis: Diagnosis and Emerging Therapeutic Strategies
edited by Raheel Ahmed and Muhammad Rashid
submission deadline 31 Jul 2025 | 2 articles | Viewed by 2213 | Submission Open
Keywords: cardiac sarcoidosis; outcomes; imaging; devices; steroids; immunosuppressants; isolated cardiac sarcoidosis; systemic cardiac sarcoidosis; endomyocardial biopsy; heterogeneity
(This special issue belongs to the Section Cardiovascular Medicine)
Oral and Maxillofacial Surgery—Current Advances and Future Directions submission deadline 31 Jul 2025 | 3 articles | Viewed by 2062 | Submission Open
Keywords: oral surgery; artificial intelligence; computer-assisted surgery; robotic surgical procedures; printing; three-dimensional; dental implants; orthognathic surgery
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Rare Respiratory Diseases: A Personal and a Public Health Problem: 3rd Edition
edited by
submission deadline 31 Jul 2025 | 2 articles | Viewed by 1940 | Submission Open
Keywords: rare diseases; rare respiratory diseases; alpha-1 antitrypsin deficiency; primary ciliary dyskinesia; cystic fibrosis; idiopathic pulmonary fibrosis; lymphangioleiomyomatosis; interstitial lung diseases; pulmonary arterial hypertension
(This special issue belongs to the Section Respiratory Medicine)
Acute Myocardial Infarction: Clinical Advances in Prognostic Stratification, Diagnosis, and Treatment submission deadline 31 Jul 2025 | 3 articles | Viewed by 1860 | Submission Open
Keywords: acute myocardial infarction (AMI); atherosclerosis; ST segment elevation myocardial infarction (STEMI); non-ST elevation myocardial infarction (NSTEMI); acute coronary syndrome (ACS); prognosis; coronary CT angiography (CCTA); cardiac magnetic resonance (CMR); reperfusion therapy; antiplatelet therapy
(This special issue belongs to the Section Cardiology)
Advances in Diagnosis, Risk Stratification, and Personalized Management in Acute Coronary Syndromes
edited by Efstratios Karagiannidis, Barbara P. Fyntanidou and Aikaterini Apostolopoulou
submission deadline 31 Jul 2025 | 1 articles | Viewed by 1574 | Submission Open
Keywords: acute coronary syndrome (ACS); cardiovascular disease (CVD); ischemic heart disease; emergency medicine; risk stratification; personalized treatment; antiplatelets; primary and secondary prevention
(This special issue belongs to the Section Cardiology)
Knee Arthroplasty Surgery: Management and Future Opportunities: 2nd Edition submission deadline 31 Jul 2025 | 3 articles | Viewed by 1291 | Submission Open
Keywords: knee; knee replacement; knee arthroplasty; knee alignment technique; robotic knee arthroplasty
(This special issue belongs to the Section Orthopedics)
Clinical Advances in Assessment Measures and Theoretical Models of Caregivers' Sensitivity and Contingency: 2nd Edition
edited by
submission deadline 31 Jul 2025 | 2 articles | Viewed by 1288 | Submission Open
Keywords: clinical caregiving; sensitivity assessment; contingency modeling; caregiver– patient interactions; mental health outcomes; novel assessment measures; therapeutic responsiveness; caregiver interventions; clinical well-being; care recipient support
(This special issue belongs to the Section Intensive Care)
Hernia Surgery and Postoperative Management
edited by Jacob Rosenberg
submission deadline 31 Jul 2025 | 2 articles | Viewed by 1194 | Submission Open
Keywords: hernia surgery; hernia repair; abdominal hernia; preoperative; intraoperative; postoperative; management; complications
(This special issue belongs to the Section General Surgery)
Innovative Systemic Treatments for Atopic Dermatitis
edited by
submission deadline 31 Jul 2025 | 2 articles | Viewed by 1131 | Submission Open
Keywords: atopic dermatitis; atopic eczema; JAK inhibitors; anti-IL-4; anti-IL-13; dupilumab; tralokinumab; lebrikizumab; abrocitinib; upadacitinib; baricitinib
(This special issue belongs to the Section Dermatology)
Attention-Deficit/Hyperactivity Disorder (ADHD): Advances in Diagnosis and Treatment
edited by Yanli Zhang-James
submission deadline 31 Jul 2025 | 2 articles | Viewed by 1095 | Submission Open
Keywords: attention-deficit/hyperactivity disorder; neurodevelopmental disorder; hyperactivity; children; adolescents; adult
(This special issue belongs to the Section Clinical Neurology)
Sustaining Success Through Innovation in Kidney Transplantation
edited by Junji Uchida
submission deadline 31 Jul 2025 | 2 articles | Viewed by 1021 | Submission Open
Keywords: kidney transplantation; long-term graft survival; immunosuppression; organ shortage; post-transplant complication
(This special issue belongs to the Section Nephrology & Urology)
Sports Injuries: Recent Advances in Prevention and Rehabilitation, 2nd Edition submission deadline 31 Jul 2025 | 1 articles | Viewed by 1006 | Submission Open
Keywords: sports injuries; treatment; musculoskeletal disorders; rehabilitation; physical rehabilitation; exercise science; sports science; injury prevention
(This special issue belongs to the Section Sports Medicine)
Artificial Intelligence and Machine Learning in Clinical Practice: Advancing Medical Imaging Analysis
edited by Guillaume Herpe
submission deadline 31 Jul 2025 | 1 articles | Viewed by 973 | Submission Open
Keywords: artificial intelligence; effectiveness; transformative impact; patient-centered radiology; workflows
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Recent Clinical Research on Nonalcoholic Fatty Liver Disease: 2nd Edition
edited by Gerond V. Lake-Bakaar
submission deadline 31 Jul 2025 | 1 articles | Viewed by 921 | Submission Open
Keywords: NAFLD; NASH; cirrhosis; hepatocellular carcinoma; hepatitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Diagnostic and Therapeutic Pathways in Cardiac Heart Failure submission deadline 31 Jul 2025 | 1 articles | Viewed by 918 | Submission Open
Keywords: heart failure; cardiomyopathies; pharmacologic therapies; device therapies; biomarkers; genetic testing; sudden cardiac death; cardiac MRI
(This special issue belongs to the Section Cardiology)
Diagnosis and Treatment of Salivary Gland Tumors: Current Advances and Future Options
edited by
submission deadline 31 Jul 2025 | 1 articles | Viewed by 785 | Submission Open
Keywords: salivary gland tumor; facial nerve; functional preservation; preoperative diagnosis; ultrasonography; intraoperative nerve monitoring; extracapsular dissection; endoscopic surgery; neck dissection; facial nerve reconstruction; anticancer therapy; postoperative radiation therapy; frey syndrome; first bite syndrome; rehabilitation
(This special issue belongs to the Section General Surgery)
Advancements in Optical Diagnostics for Head and Neck: Current Trends and Future Directions
edited by
submission deadline 31 Jul 2025 | 1 articles | Viewed by 703 | Submission Open
Keywords: head and neck cancer; head and neck surgery; fluorescence imaging; Raman spectroscopy; optical coherence tomography; photoacoustic imaging; photodiagnosis; photodynamic therapy
(This special issue belongs to the Section Otolaryngology)
Prevention, Diagnosis and Treatment of Oral Mucosal Diseases
edited by
submission deadline 31 Jul 2025 | 1 articles | Viewed by 703 | Submission Open
Keywords: oral mucosal diseases; oral mucositis; oral precancerous lesions; oral cancer; oral potentially malignant disorders; OPMDs; oral leukoplakia
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Advances in Systemic Sclerosis submission deadline 31 Jul 2025 | 1 articles | Viewed by 569 | Submission Open
Keywords: systemic sclerosis; Raynaud’ s phenomenon; digital ulcers; scleroderma renal crisis; pulmonary arterial hypertension; interstitial lung disease; fibrosis
(This special issue belongs to the Section Immunology)
Male Fertility in the Modern Age: Challenges and Opportunities
edited by Angelo Marino
submission deadline 31 Jul 2025 | Viewed by 506 | Submission Open
Keywords: male infertility; semen parameters; sperm selection; IVF/ICSI
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Foot and Ankle Surgery: Current Advances and Prospects
edited by
submission deadline 31 Jul 2025 | 1 articles | Viewed by 429 | Submission Open
Keywords: foot and ankle surgery; foot pathologies; ankle disease and trauma; diabetic foot; epidemiology; clinical anatomy; foot orthoses; weight-bearing CT
(This special issue belongs to the Section Orthopedics)
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