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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Advances in Minimally Invasive Urologic Surgery
edited by , Fabio Crocerossa and
submission deadline 31 Jul 2025 | Viewed by 330 | Submission Open
Keywords: urology; uro-oncology; uro-gynecology; robotic surgery; laparoscopy; robot-assisted; artificial intelligence
(This special issue belongs to the Section Nephrology & Urology)
Hip Fracture and Surgery: Clinical Updates and Challenges
edited by
submission deadline 31 Jul 2025 | Viewed by 298 | Submission Open
Keywords: antiosteoporosis medication; fracture liaison service; osteosynthesis; total hip arthroplasty; hemiarthroplasty
(This special issue belongs to the Section Orthopedics)
Machine Learning and Artificial Intelligence in Neurosurgery
edited by Jan Oliver Neumann and
submission deadline 31 Jul 2025 | Viewed by 245 | Submission Open
Keywords: artificial intelligence; neurosurgery; neuro-oncology; spinal neurosurgery; neuro-ICU; stereotactic neurosurgery; pre-operative planning
(This special issue belongs to the Section Clinical Neurology)
Application of Artificial Intelligence in Cardiology submission deadline 31 Jul 2025 | Viewed by 233 | Submission Open
Keywords: artificial intelligence; cardiology; clinical practice; valvular heart disease; arrhythmias; device therapy; machine learning
(This special issue belongs to the Section Cardiology)
Kidney Transplantation: Challenges, Advances and Lessons Learnt
edited by Karim Soliman and
submission deadline 31 Jul 2025 | Viewed by 208 | Submission Open
Keywords: kidney transplantation; nephrology; transplant medicine; patient selection criteria; immunosuppressive treatment; long-term outcomes; graft survival; complication; multi-organ transplant consideration; innovation
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Investigations into Diagnosing and Managing Strabismus
edited by Mario Cantó Cerdán and Pilar Cacho-Martínez
submission deadline 31 Jul 2025 | Viewed by 192 | Submission Open
Keywords: oculomotricity; binocular vision; strabismus; ocular motility disorders; exotropia; esotropia; video oculography; eye tracker; ocular deviation
(This special issue belongs to the Section Ophthalmology)
Clinical Advances in Treatment for Venous Thromboembolism
edited by and Georgia Kaiafa
submission deadline 31 Jul 2025 | Viewed by 177 | Submission Open
Keywords: venous thromboembolism; anticoagulation; cancer-associated thrombosis; thrombosis in MPNs; thrombosis in multiple myeloma; antiphospholipidic syndrome; thrombosis in PNH; thrombosis in hemoglobinopathies; thrombophilia; pregnancy and thrombophilia; reversal of anticoagulants; thromboprophylaxis
(This special issue belongs to the Section Hematology)
Clinical Insights into Pediatric Critical Care
edited by Katherine Biagas and Daniel E Sloniewsky
submission deadline 31 Jul 2025 | Viewed by 170 | Submission Open
Keywords: PICU; anemia; blood transfusion; critically ill children; traumatic hemorrhage
(This special issue belongs to the Section Intensive Care)
Novel Developments on Diagnosis and Treatment of Atrial Fibrillation
edited by and Mihaela-Viviana Ivan
submission deadline 31 Jul 2025 | Viewed by 162 | Submission Open
Keywords: atrial fibrillation; supraventricular arrhythmia; cardiovascular risk; oxidative stress; inflammation
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Management and Treatment of Psoriasis
edited by
submission deadline 31 Jul 2025 | Viewed by 156 | Submission Open
Keywords: psoriasis; biological drugs; personalized medicine; comorbidities; real-world evidence
(This special issue belongs to the Section Dermatology)
Hand Surgery Clinical Advances and Practice Updates
edited by Guy Rubin
submission deadline 31 Jul 2025 | Viewed by 156 | Submission Open
Keywords: trauma; mallet; burn; nerve; tendon
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Heart Failure and Its Complications: Advances in Clinical Diagnosis and Management, 2nd Edition
edited by
submission deadline 31 Jul 2025 | Viewed by 151 | Submission Open
Keywords: heart failure; complications; arrhythmias; pharmacological therapy; devices; mechanical circulatory support
(This special issue belongs to the Section Cardiology)
Clinical Outcomes in Urologic Oncology
edited by
submission deadline 31 Jul 2025 | Viewed by 151 | Submission Open
Keywords: urologic oncology; surgical oncology; bladder cancer; upper tract urothlial carcinoma; prostate cancer; testis cancer; penile cancer; immunotherapy; chemotherapy; stereotactic body radiotherapy
(This special issue belongs to the Section Nephrology & Urology)
Advanced Diagnostic and Therapeutic Strategies for Sarcoidosis submission deadline 31 Jul 2025 | Viewed by 137 | Submission Open
Keywords: sarcoidosis; cardiac sarcoidosis; pulmonary fibrosis; magnetic resonance imaging; FDG-PET/CT; echocardiography; neurosarcoidosis; differential diagnosis; hypercalcaemia; IGRA; sarcoidosis-associated pulmonary hypertension; fatigue; corticosteroids; metotrexat; infliximab; antifibrotic treatment; lung transplantation; artificial intelligence; broncho-alveolar lavage; cytokines
(This special issue belongs to the Section Respiratory Medicine)
Disorders of Consciousness in Ischemic Stroke: Evaluation, Management and Prognostic Implications
edited by
submission deadline 31 Jul 2025 | Viewed by 129 | Submission Open
Keywords: disorders of consciousness; ischemic stroke; prognosis; coma; neuroprognostication
(This special issue belongs to the Section Clinical Neurology)
Haemophilia: Current Treatment and Clinical Outcomes, Challenges and Opportunities: 2nd Edition
edited by
submission deadline 31 Jul 2025 | Viewed by 117 | Submission Open
Keywords: haemophilia A and B; FVIII EHL; FIX EHL; prophylaxis; emicizumab; health-related quality of life; population pharmacokinetics
(This special issue belongs to the Section Hematology)
State of the Art in Surgical Treatment for Colorectal Cancer
edited by Saulius Švagždys
submission deadline 31 Jul 2025 | Viewed by 104 | Submission Open
Keywords: laparoscopic and robotic surgery; endoscopic and minimally invasive surgery; colorectal cancer; energy devices; staplers
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Shaping Modern Gastroenterology: Bridging Advancements in Digestive Endoscopy and Clinical Research
edited by Manuele Furnari and Stefano Kayali
submission deadline 3 Aug 2025 | Viewed by 95 | Submission Open
Keywords: digestive endoscopy; gastrointestinal disorders; endoscopic ultrasound (EUS); endoscopic retrograde cholangiopancreatography (ERCP); therapeutic endoscopy; artificial intelligence; pancreatic and biliary diseases; small bowel pathology; early neoplastic lesions; inflammatory bowel diseases (IBDs); translational gastroenterology; endoscopic submucosal dissection (ESD); per-oral endoscopic myotomy (POEM); endoscopic imaging; gastrointestinal pathophysiology
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) as a Global but Not Liver-Limited Health Challenge—from Disease Pathogenesis to Therapeutic Targets
edited by Beata Kasztelan-Szczerbinska and Halina Cichoż-Lach
submission deadline 5 Aug 2025 | 2 articles | Viewed by 1874 | Submission Open
Keywords: metabolic dysfunction-associated steatotic liver disease (MASLD); non-alcoholic fatty liver disease (NAFLD); hepatic steatosis; multiorgan metabolic interactions; liver-related morbidity; liver-related mortality; lipid metabolism; cardiovascular metabolic complications; metabolic dysfunction-related cancer
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Recent Advances in Prevention, Management, and Rehabilitation of Head and Neck Injuries
edited by , Pier Enrico Gallenga and
submission deadline 5 Aug 2025 | 1 articles | Viewed by 789 | Submission Open
Keywords: neck injuries; whiplash injuries; head injuries; concussion; neck pain; cervicalgia; post-concussive syndrome; post-concussive symptoms; vision disorders; hearing disorders; emergency care; emergency therapies; physical medicine and rehabilitation; musculoskeletal rehabilitation; sports medicine
(This special issue belongs to the Section Sports Medicine)
State of the Art: Catheter Ablation of Atrial Fibrillation
edited by and Cinzia Monaco
submission deadline 10 Aug 2025 | 3 articles | Viewed by 4719 | Submission Open
Keywords: atrial fibrillation; catheter ablation; pulsed-field ablation; supraventricular arrhythmias; atrial substrate
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Advances in Artificial Intelligence in Urology
edited by
submission deadline 10 Aug 2025 | 4 articles | Viewed by 4044 | Submission Open
Keywords: artificial intelligence; deep learning; artificial neural networks; computer; AI; machine learning
(This special issue belongs to the Section Nephrology & Urology)
Immune Dysregulation in Inborn Errors of Immunity: From Allergy to Autoimmunity and Lymphoproliferation submission deadline 10 Aug 2025 | 2 articles | Viewed by 2779 | Submission Open
Keywords: immune dysregulation; immunodeficiency; autoimmunity; allergy; lymphoproliferation; inborn errors of immunity
(This special issue belongs to the Section Immunology)
The Clinical Role of Imaging in Lung Diseases
edited by and Claire Van Ngoc Ty
submission deadline 10 Aug 2025 | 2 articles | Viewed by 2370 | Submission Open
Keywords: lung screening; lung cancer; acute respiratory distress; pulmonary embolism; chronic obstructive pulmonary disease; imaging
(This special issue belongs to the Section Respiratory Medicine)
Clinical Updates and Perspectives of Implant Dentistry submission deadline 13 Aug 2025 | 1 articles | Viewed by 3417 | Submission Open
Keywords: osseointegration; soft tissue integration; peri-implant diseases
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Management of Patients with Heart Failure—2nd Edition
edited by
submission deadline 13 Aug 2025 | 3 articles | Viewed by 1002 | Submission Open
Keywords: acute heart failure; chronic heart failure; treatment options; management of heart failure; life style changes; diagnosis of heart failure
(This special issue belongs to the Section Cardiovascular Medicine)
Trends and Prospects in Shoulder and Elbow Surgery
edited by Lorenzo Diaz Balzani, Erika Albo, and
submission deadline 14 Aug 2025 | 4 articles | Viewed by 3480 | Submission Open
Keywords: shoulder; elbow; arthroplasty; arthroscopy; rehabilitation; trauma; minimally invasive; regenerative medicine; implant technology
(This special issue belongs to the Section Orthopedics)
Amyloid: From Heart to Brain submission deadline 15 Aug 2025 | 4 articles | Viewed by 3048 | Submission Open
Keywords: amyloid; heart; brain; interactions; small vessel disease; takotsubo; Alzheimer’ s disease
(This special issue belongs to the Section Cardiology)
Novel Therapeutic Strategies for Acute Myeloid Leukemia
edited by Giovangiacinto Paterno and
submission deadline 15 Aug 2025 | 2 articles | Viewed by 1853 | Submission Open
Keywords: acute myeloid leukemia; novel treatments; supportive care; quality of life; patients’ outcomes; targeted therapy
(This special issue belongs to the Section Hematology)
Sepsis: Current Updates and Perspectives
edited by Ecaterina Scarlatescu
submission deadline 15 Aug 2025 | 2 articles | Viewed by 1798 | Submission Open
Keywords: sepsis biomarkers; diagnostic tools; cytokines; inflammation; infection; antibiotherapy; blood purification; novel therapies
(This special issue belongs to the Section Intensive Care)
Otolaryngology—Head and Neck Surgery: Current Trends and Challenges
edited by and Lorenzo Maria Gaini
submission deadline 15 Aug 2025 | 2 articles | Viewed by 859 | Submission Open
Keywords: minimally invasive surgery; endoscopy; exoscopy; airway surgery; salivary glands diseases; otitis media; pediatric otolaryngology; head and neck surgery
(This special issue belongs to the Section Otolaryngology)
Cardiac Electrophysiology: Focus on Clinical Practice submission deadline 15 Aug 2025 | 1 articles | Viewed by 663 | Submission Open
Keywords: cardiomyopathy; arrhythmia; heart rhythm; atrial fibrillation; ventricular tachycardia; sudden cardiac death; mapping; ablation; pulsed field ablation (PFA); device; pacemaker; left bundle branch area pacing (LBBAP); conduction system pacing (CSP); implantable cardioverter-defibrillator (ICD); leadless pacing; extraction
(This special issue belongs to the Section Cardiology)
Application of Magnetic Resonance Imaging (MRI) in the Diagnosis, Staging and Follow-Up of Oncological Diseases
edited by
submission deadline 15 Aug 2025 | Viewed by 310 | Submission Open
Keywords: MRI; cancer; oncology; diagnosis; staging; follow-up; radiomics
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Oral and Maxillofacial Radiology: Clinical Progress and New Directions
edited by Zbigniew Serafin and
submission deadline 15 Aug 2025 | 1 articles | Viewed by 189 | Submission Open
Keywords: artificial intelligence (AI); computed-assisted diagnosis (CAD); cone beam computed tomography (CBCT); convolutional neural network (CNN); computed tomography (CT); magnetic resonance (MR); PET-CT
(This special issue belongs to the Section Nuclear Medicine & Radiology)
The Role of Cardiac Rehabilitation After Myocardial Infarction, Coronary Artery Bypass Surgery, and in Other Cardiac Diseases submission deadline 15 Aug 2025 | Viewed by 176 | Submission Open
Keywords: cardiac rehabilitation; coronary artery disease; myocardial infarction; coronary artery bypass surgery; heart failure; ventricular assist device; heart transplantation; cardiomyopathies; cardiac remodeling; illness perception; treatment adherence; gender difference; biomarkers; endothelial function
(This special issue belongs to the Section Cardiology)
Diagnosis and Treatment for Bone Tumor
edited by Antonio Ziranu and Luigi Cianni
submission deadline 15 Aug 2025 | Viewed by 128 | Submission Open
Keywords: bone tumor; oncology; osteosarcoma; chondrosarcoma; megaprosthesis; bone resection; chemotherapy; radiotherapy; sarcoma; custom-made
(This special issue belongs to the Section Orthopedics)
Advances in Traumatic Brain Injury: Causes and Recovery
edited by Antonio Bonora
submission deadline 15 Aug 2025 | Viewed by 104 | Submission Open
Keywords: mild traumatic brain injury; TBI; brain injuries; neuroimaging; rehabilitation
(This special issue belongs to the Section Brain Injury)
Clinical Management and Rehabilitation of Spinal Cord Injury
edited by Tsunehiko Konomi
submission deadline 20 Aug 2025 | 10 articles | Viewed by 21092 | Submission Open
Keywords: spinal cord injury; rehabilitation; diagnosis and prognosis; comprehensive management; social support
(This special issue belongs to the Section Orthopedics)
Clinical Aspects of Return to Sport After Injuries
edited by and
submission deadline 20 Aug 2025 | 5 articles | Viewed by 15496 | Submission Open
Keywords: musculoskeletal system; tissue overload; diagnostic methods; rehabilitation; treatment; injury prevention; return to sport; rehabilitation medicine; sports medicine
(This special issue belongs to the Section Sports Medicine)
Gastrointestinal Cancer: Outcomes and Therapeutic Management
edited by Maximos Frountzas
submission deadline 20 Aug 2025 | 8 articles | Viewed by 12219 | Submission Open
Keywords: surgical oncology; gastrointestinal cancer; esophageal; gastric; hepatic; biliary; pancreatic; colon; rectal; neoplasm
(This special issue belongs to the Section Oncology)
Harnessing Photobiomodulation Light for Therapeutic or Prevention of Human Diseases
edited by
submission deadline 20 Aug 2025 | 4 articles | Viewed by 7711 | Submission Open
Keywords: neurorehabilitation; supportive care for cancer; reproductive health; dental and oral diseases; viral and bacterial diseases; wound care; dermatology; sports rehabilitation; bone and musculoskeletal diseases; PBM mechanism; ophthalmology; stem cells and regenerative medicine; pain and addiction management; PBM-tissue interaction
Cardiovascular and Cerebrovascular Emergencies: Advances in Clinical Research
edited by
submission deadline 20 Aug 2025 | 5 articles | Viewed by 5736 | Submission Open
Keywords: cardiovascular emergencies; neurovascular emergencies; stroke; cardiac arrest; acute myocardial infarction
(This special issue belongs to the Section Cardiovascular Medicine)
Traumatic Brain Injury: Emergency Management, Prevention of Secondary Injury, and Rehabilitation
edited by and Lori Shutter
submission deadline 20 Aug 2025 | 3 articles | Viewed by 5469 | Submission Open
Keywords: traumatic brain injury; neuromonitoring; neurocritical care; neurorehabilitation; secondary injury; outcome; prognostication
(This special issue belongs to the Section Brain Injury)
Recent Developments in Gynecological Endocrinology submission deadline 20 Aug 2025 | 4 articles | Viewed by 4871 | Submission Open
Keywords: amenorrhea; puberty; PCOS; premature ovarian insufficiency; endometriosis; infertility; pregnancy; hormones; menopause
(This special issue belongs to the Section Obstetrics & Gynecology)
Frailty in the Elderly: Risk Factors, Prevention and Clinical Management
edited by
submission deadline 20 Aug 2025 | 3 articles | Viewed by 4463 | Submission Open
Keywords: sarcopenia; frailty; elderly; geriatrics; personalized medicine
(This special issue belongs to the Section Epidemiology & Public Health)
New Advances in Prenatal Diagnosis and Newborn Screening submission deadline 20 Aug 2025 | 3 articles | Viewed by 3750 | Submission Open
Keywords: sonographic parameters; molecular markers; extravillous and villous trophoblasts; perinatal ultrasound; serum markers for complications of pregnancy; histopathology of the placenta; neonatal pathological conditions
(This special issue belongs to the Section Obstetrics & Gynecology)
Interstitial Lung Disease: From Diagnosis to Treatment
edited by and Tomohisa Baba
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3316 | Submission Open
Keywords: interstitial pneumonia; diagnosis; virus infection; collagen vascular disease-related interstitial pneumonia; differen-tial diagnosis; lung sounds
(This special issue belongs to the Section Respiratory Medicine)
Advances in Kidney Transplantation
edited by Pedro Ruiz-Esteban, Domingo Hernández and Veronica López
submission deadline 20 Aug 2025 | 3 articles | Viewed by 2271 | Submission Open
Keywords: kidney transplant; acute rejection; biomarkers; artificial intelligence; post-transplant complications; graft survival
(This special issue belongs to the Section Nephrology & Urology)
Liver Transplantation: Current Hurdles and Future Perspectives
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 1826 | Submission Open
Keywords: machine perfusion; donation after circulatory death; liver preservation; living donation; acute-on-chronic liver failure; frailty; liver malignancies; surgical technique; liver transplant recipient care; immunosuppression
(This special issue belongs to the Section General Surgery)
Endodontic and Periodontal Medicine: Systemic Implications of Oral Infections submission deadline 20 Aug 2025 | 3 articles | Viewed by 1699 | Submission Open
Keywords: apical periodontitis; endodontic medicine; periodontal disease; periodontal medicine; pulpitis; systemic diseases; root canal treatment
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
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