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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Future-Proof Care for Patients with Kidney Stones
edited by and Oliver Wiseman
submission deadline 20 Aug 2026 | 2 articles | Viewed by 759 | Submission Open
Keywords: effectiveness; resilience; prevention; care pathways; urolithiasis; kidney stones; PCNL; URS; ESWL; quality of life
(This special issue belongs to the Section Nephrology & Urology)
Endoscopic Imaging for the Diagnosis and Treatment of Gastrointestinal Diseases
edited by Mariana Jinga and
submission deadline 20 Aug 2026 | 1 articles | Viewed by 755 | Submission Open
Keywords: endoscopy; endoscopic ultrasound; endoscopic retrograde cholangiopancreatography; artificial intelligence; diagnosis; therapy; decision making; endobiopsy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Update on Prenatal Diagnosis and Maternal Fetal Medicine
edited by Gianluca Campobasso
submission deadline 20 Aug 2026 | 1 articles | Viewed by 740 | Submission Open
Keywords: fetal medicine; malformations; obstetric; prenatal diagnosis; artificial intelligence
(This special issue belongs to the Section Obstetrics & Gynecology)
Contemporary Coronary Intervention: Innovation, Evidence, and Patient-Centred Outcomes
edited by Kevin Liou
submission deadline 20 Aug 2026 | 1 articles | Viewed by 707 | Submission Open
Keywords: percutaneous coronary interventions; coronary imaging; coronary physiology; precision medicine; CHIP PCI; stent-less technologies; clinical outcomes; pharmacotherapy in PCI; biomarkers; artificial intelligence in PCI; sustainability in PCI
(This special issue belongs to the Section Cardiology)
Spine Surgery and Postoperative Management
edited by Mitchell K. Ng
submission deadline 20 Aug 2026 | 1 articles | Viewed by 592 | Submission Open
Keywords: spine surgery; perioperative care; enhanced recovery after surgery (ERAS); multimodal analgesia; opioid-sparing strategies; neuromonitoring; perioperative optimization
(This special issue belongs to the Section Orthopedics)
Current Trends and Progress in Eating Disorders and Obesity Management
edited by Davide Gravina, and
submission deadline 20 Aug 2026 | 1 articles | Viewed by 577 | Submission Open
Keywords: eating disorders; anorexia nervosa; bulimia nervosa; binge-eating disorder; ARFID; obesity; neuromodulation; biomarkers; gut microbiome; pharmacological interventions; incretin receptor agonists; GLP-1; metreleptin; psychedelics
(This special issue belongs to the Section Mental Health)
Spine Surgery: Clinical Advances and Future Directions—2nd Edition
edited by Eun-Sang Kim and
submission deadline 20 Aug 2026 | 1 articles | Viewed by 542 | Submission Open
Keywords: spine surgery; back pain; endoscopic spine surgery; cage implantation; neck pain
(This special issue belongs to the Section Clinical Neurology)
Anterior Segment Disorders
edited by Itay Lavy and
submission deadline 20 Aug 2026 | 1 articles | Viewed by 408 | Submission Open
Keywords: anterior segment disorders; corneal disease; cataract surgery; ocular surface disease; surgical outcomes; surgical techniques; artificial intelligence in diagnosis; diagnostic imaging; pharmacological and surgical interventions; refractive errors; anterior uveitis; keratitis; corneal ectasia; quality of life
(This special issue belongs to the Section Ophthalmology)
Maxillofacial Surgery in the Modern Era: Surgical Advances and Clinical Innovation submission deadline 20 Aug 2026 | Viewed by 396 | Submission Open
Keywords: maxillofacial surgery; oral surgery; craniofacial surgery; plastic surgery; bone
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
New Insights into Gastrointestinal Surgery: Advances in Techniques and Treatment Approaches
edited by Gabriella Teresa Capolupo
submission deadline 20 Aug 2026 | Viewed by 395 | Submission Open
Keywords: gastroenterology; gastrointestinal surgery; colorectal surgery; robotic surgery; technologies; minimally invasive surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Heart Failure and Transplant Cardiology: Latest Advances and Prospects
edited by Monika Budnik
submission deadline 20 Aug 2026 | 1 articles | Viewed by 371 | Submission Open
Keywords: heart failure; heart transplantation; bridge to transplant; mechanical circulatory support; cardiomyopathies
(This special issue belongs to the Section Cardiology)
Clinical Updates on Reproductive Endocrinology in Children and Adolescents submission deadline 20 Aug 2026 | Viewed by 328 | Submission Open
Keywords: reproductive endocrinology; adolescents; male hypogonadism; female hypogonadism; reproductive metabolism; PCOS; POF; receptor abnormalities; menstrual cycle; transgender health; CAH; ovaries; gonads; hormones; sex development; amenorrhea; estrogen resistance; androgen resistance; teen pregnancy; oncology; preservation of fertility
(This special issue belongs to the Section Clinical Pediatrics)
State of the Art in Bladder Cancer: Diagnostics and Treatment Strategies
edited by
submission deadline 20 Aug 2026 | Viewed by 301 | Submission Open
Keywords: bladder cancer; photodynamic diagnosis (PDD); bladder-sparing strategies; robotic-assisted surgery; single-port robotic cystectomy; older patients; immunotherapy; intravesical therapy; bladder preservation; minimally invasive urology; advanced bladder cancer; diagnostic innovation
(This special issue belongs to the Section Nephrology & Urology)
Optimizing Rehabilitation in Kidney Disease
edited by Henry H. L. Wu and Rajkumar Chinnadurai
submission deadline 20 Aug 2026 | Viewed by 277 | Submission Open
Keywords: chronic kidney disease; renal rehabilitation; exercise intervention; nutrition; multidisciplinary; frailty; physical conditioning
(This special issue belongs to the Section Clinical Rehabilitation)
Clinical Advances in Hearing Loss: Diagnosis, Treatment, and Management
edited by
submission deadline 20 Aug 2026 | Viewed by 274 | Submission Open
Keywords: hearing loss; deafness; bone conduction implants; middle ear implants; cochlear implants; myringoplasty; tympanoplasty; stapedotomy; ossicular chain reconstruction; imaging; audiological diagnostic
(This special issue belongs to the Section Otolaryngology)
Precision Neuroimaging in Mental and Behavioral Health Research
edited by Thomas Vanicek and Arkadiusz Komorowski
submission deadline 20 Aug 2026 | Viewed by 273 | Submission Open
Keywords: psychiatry; neuroimaging; addiction; substance use disorders (SUD); attention deficit hyperactivity disorder (ADHD); imaging genomics; imaging transcriptomics
(This special issue belongs to the Section Mental Health)
Clinical Advances in Orthopedic Infections: 2nd Edition
edited by
submission deadline 20 Aug 2026 | Viewed by 267 | Submission Open
Keywords: orthopedic surgery; orthopedic infections; periprosthetic joint infection; surgical site infection; infection management
(This special issue belongs to the Section Orthopedics)
Bleeding and Thrombotic Complications in Patients with Premalignant Hematologic Conditions: Diagnostic and Therapeutic Challenges
edited by Vasiliki Gkalea and Despina Fotiou
submission deadline 20 Aug 2026 | Viewed by 261 | Submission Open
Keywords: bleeding; thrombosis; hematologic malignancies; premalignant hematologic conditions; clonal hematopoiesis of indeterminate potential (CHIP); clonal cytopenias of undetermined significance (CCUS); monoclonal gammopathy of undetermined significance (MGUS); monoclonal B-cell lymphocytosis (MBL); monoclonal gammopathy of thrombotic significance (MGTS); VITT-like MGTS
(This special issue belongs to the Section Hematology)
Retinal Diseases: Recent Advances in Diagnosis and Treatment—2nd Edition
edited by Dario Giorgio and Dario Pasquale Mucciolo
submission deadline 20 Aug 2026 | Viewed by 258 | Submission Open
Keywords: retinal diseases; retinal degeneration; macular degeneration; OCT; retinal imaging
(This special issue belongs to the Section Ophthalmology)
The Liver–Kidney Axis in Metabolic Diseases: Biomarkers and Clinical Implications
edited by
submission deadline 20 Aug 2026 | Viewed by 254 | Submission Open
Keywords: liver; kidney; cross-organ crosstalk; mechanisms; biomarkers; metabolic diseases; clinical implications
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Current Concepts and Technological Innovations in Hepato-Pancreato-Biliary Surgery and Transplantation
edited by Michele Finotti and Francesco D’Amico
submission deadline 20 Aug 2026 | Viewed by 253 | Submission Open
Keywords: hepato-pancreato-biliary surgery; hepato-pancreato-biliary transplantation; pancreatic cancer; hepatobiliary cancer; vascular reconstruction; minimally invasive in hepato-pancreato-biliary surgery; robotic techniques; organ-preservation strategies
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Integrated Ozone Therapy and Physical Rehabilitation for Musculoskeletal Disorders: A Comprehensive Approach submission deadline 20 Aug 2026 | Viewed by 251 | Submission Open
Keywords: ozone therapy; physical rehabilitation; musculoskeletal disorders; integrative medicine; rehabilitation therapy; regenerative medicine; clinical outcomes
(This special issue belongs to the Section Clinical Rehabilitation)
Clinical Advances in Adult Deformities and Spinal Disorders: Surgical Treatment and Pre- and Post-Operative Re-Habilitation
edited by
submission deadline 20 Aug 2026 | Viewed by 249 | Submission Open
Keywords: scoliosis; spine; kyphosis; degenerative spine; spine surgery
(This special issue belongs to the Section Orthopedics)
Breaking the Barrier: Early Detection of Pancreatic Ductal Adenocarcinoma (PDAC) submission deadline 20 Aug 2026 | Viewed by 248 | Submission Open
Keywords: pancreatic ductal adenocarcinoma (PDAC); pancreatic cancer; IPMN; PDAC screening; early PDAC detection; PDAC biomarkers; CT; NMR
(This special issue belongs to the Section Oncology)
Optimizing Blood Management in Perioperative Cardiac Care: A Multidisciplinary Approach
edited by
submission deadline 20 Aug 2026 | Viewed by 248 | Submission Open
Keywords: perioperative cardiac care; patient blood management; cardiac surgery; blood transfusion; transfusion thresholds; bleeding management; hemostatic therapy; anticoagulation management; point‑of‑care coagulation testing
(This special issue belongs to the Section Cardiology)
Advances in Pulmonary Embolism Therapeutics
edited by
submission deadline 20 Aug 2026 | Viewed by 238 | Submission Open
Keywords: acute pulmonary embolism; chronic pulmonary embolism; chronic thromboembolic disease; chronic thromboem-bolic pulmonary hypertension; catheter-directed therapy; pulmonary endarterectomy; balloon pulmonary angio-plasty
(This special issue belongs to the Section Vascular Medicine)
Current Trends and Innovations in Coronary Artery Disease and Myocardial Ischemia: Second Edition
edited by
submission deadline 20 Aug 2026 | Viewed by 236 | Submission Open
Keywords: coronary artery disease; fractional flow reserve; invasive coronary angiography; cardiac CT; cardiac MRI
(This special issue belongs to the Section Cardiovascular Medicine)
Physiotherapy: Multidisciplinary Interventions and Digital Health submission deadline 20 Aug 2026 | Viewed by 227 | Submission Open
Keywords: physiotherapy; rehabilitation; physical medicine; digital health; telemedicine; virtual reality; augmented reality; artifi-cial intelligence; robotic rehabilitation; wearable sensors; VR for educative goals; musculoskeletal; neurological; cognitive; pediatric; pulmonary; cardiac and gyneco-obstetric disorders; fibromyalgia syndrome; chronic pain; older adults
(This special issue belongs to the Section Clinical Rehabilitation)
Advances in Diagnosis, Monitoring, and Treatment of Myocardial Infarction
edited by
submission deadline 20 Aug 2026 | Viewed by 223 | Submission Open
Keywords: myocardial infarction (MI); occlusion myocardial infarction (OMI); myocardial infarction with non-obstructive coronary arteries (MINOCA); diagnosis; monitoring; treatment
(This special issue belongs to the Section Cardiovascular Medicine)
Updates on Embolization and Embolotherapy for Benign Prostatic Hyperplasia and Men’s Health
edited by Sandeep L. Bagla, Ari J. Isaacson and Abin Sajan
submission deadline 20 Aug 2026 | Viewed by 223 | Submission Open
Keywords: benign prostatic hyperplasia; prostatic artery embolization; men’ s health; lower urinary tract symptoms; embolization therapy; radiation safety; prostate cancer and radiotherapy
(This special issue belongs to the Section Nephrology & Urology)
Novel Approaches in Obsessive–Compulsive and Related Spectrum Disorders
edited by and Andrea D. Guastello
submission deadline 20 Aug 2026 | Viewed by 217 | Submission Open
Keywords: OCD; misophonia; hoarding; tic disorders; assessment; treatment
(This special issue belongs to the Section Mental Health)
Hepatobiliary–Pancreatic Surgery in the Era of Interventional Radiology
edited by
submission deadline 20 Aug 2026 | Viewed by 212 | Submission Open
Keywords: hepato-biliary– pancreatic surgery; interventional radiology; percutaneous biliary drainage; percutaneous pancre-atic drainage; portal vein embolization; tumor ablation; minimally invasive surgery; cryoablation; thermoablation
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances and Perspectives in Neuro-Oncology
edited by Mariko Sato and
submission deadline 20 Aug 2026 | Viewed by 212 | Submission Open
Keywords: neuro-oncology; diagnosis; treatment; minimally invasive surgery; skull base surgery; brain tumor; radiosurgery; neuro endoscopy
(This special issue belongs to the Section Clinical Neurology)
Managing Chronic Kidney Disease: Current Practices and Future Perspectives
edited by Maria L. Gonzalez-Suarez
submission deadline 20 Aug 2026 | Viewed by 211 | Submission Open
Keywords: chronic kidney disease; diabetic kidney disease; kidney failure; guideline-directed therapies; SLGT 2 inhibitors; GLP1 receptor agonists
(This special issue belongs to the Section Nephrology & Urology)
Targeting Extravalvular Burden Associated with Valvular Heart Disease
edited by
submission deadline 20 Aug 2026 | Viewed by 211 | Submission Open
Keywords: valvular heart disease; systemic disorder; extravalvular burden; valve dysfunction; valve intervention; multimodality imaging
(This special issue belongs to the Section Cardiology)
Personalised and Precision Pharmacotherapy: Data-Driven Therapeutic Optimisation in Real-World Clinical Practice submission deadline 20 Aug 2026 | Viewed by 206 | Submission Open
Keywords: precision pharmacotherapy; personalised medicine  ; pharmacokinetics and pharmacodynamics  ; therapeutic drug  ; monitoring real-world evidence  ; multimorbidity  ; medication appropriateness  ; model-informed precision dosing; does individualisation; clinical decision support
(This special issue belongs to the Section Pharmacology)
From Histology to Clinical Immunology: Integrated Diagnosis in Oral and Maxillofacial Diseases
edited by Fabiana Nicita
submission deadline 20 Aug 2026 | Viewed by 202 | Submission Open
Keywords: clinical immunology; histology; immunopathology; immune-mediated oral disease; biomarkers
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Therapeutic Advances and Emerging Treatments in Inflammatory Bowel Disease
edited by
submission deadline 20 Aug 2026 | Viewed by 202 | Submission Open
Keywords: inflammatory bowel disease; therapeutic advances emerging treatments; biologics and small molecules; precision medicine in IBD; pharmacokinetic model
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Approaches of Intracranial Aneurysm and Subarachnoid Hemorrhage
edited by Sylvia Bele
submission deadline 20 Aug 2026 | Viewed by 202 | Submission Open
Keywords: aSAH; clipping or coiling; extracranial complications; cerebral vasospasm; ICU treatment
(This special issue belongs to the Section Clinical Neurology)
Recent Advances in Hypercholesterolemia
edited by Ana Catarina Alves
submission deadline 20 Aug 2026 | Viewed by 195 | Submission Open
Keywords: hypercholesterolemia; cardiovascular risk; molecular diagnostics; variants of uncertain significance (VUS); functional characterisation; precision medicine; lipid-lowering therapy
(This special issue belongs to the Section Endocrinology & Metabolism)
Revisional and Conversion Bariatric Surgery: Safety and Outcomes
edited by Jerry Dang and Thomas H. Shin
submission deadline 20 Aug 2026 | Viewed by 190 | Submission Open
Keywords: revisional bariatric surgery; conversion surgery; weight recurrence; surgical outcomes; sleeve gastrectomy; roux-en-y gastric bypass; post-bariatric complications; GERD
(This special issue belongs to the Section General Surgery)
Recent Clinical Perspectives on Chronic Kidney Disease
edited by Luca Visconti
submission deadline 20 Aug 2026 | Viewed by 190 | Submission Open
Keywords: chronic kidney disease; nephrology; hemodialysis; renal impairment; renal replacement therapy; new therapeutic approaches in CKD; clinical trials; renal complications
(This special issue belongs to the Section Nephrology & Urology)
Carotid Artery Disease: Current Hurdles and Future Perspectives
edited by Andrej Udelnow
submission deadline 20 Aug 2026 | Viewed by 190 | Submission Open
Keywords: carotid artery disease; carotid stenosis; endovascular technique; CEUS; elastography; high resolution CTA; atherosclerotic diseases; inflammatory diseases
(This special issue belongs to the Section Vascular Medicine)
Clinical Advances in Diagnosis and Treatment of Metastatic Spinal Tumor
edited by
submission deadline 20 Aug 2026 | Viewed by 186 | Submission Open
Keywords: metastatic spinal tumors; spine surgery; bone metastasis; imaging diagnosis; minimally invasive surgery; decompression surgery; fixation surgery; emergency surgery; prognosis prediction; elderly patients; nutrition; mental health
(This special issue belongs to the Section Oncology)
Diagnosis and Clinical Management in Hematologic Oncology
edited by Sunil Lakhwani and José María Raya-Sánchez
submission deadline 20 Aug 2026 | 1 articles | Viewed by 185 | Submission Open
Keywords: hematologic malignancies; lymphoma; multiple myeloma; acute leukemia; myeloproliferative neoplasms; molecular diagnostics; targeted therapy; immunotherapy; prognostic biomarkers; clinical management
(This special issue belongs to the Section Hematology)
Exploring Female Infertility: Advances, Challenges, and Emerging Solutions
edited by
submission deadline 20 Aug 2026 | Viewed by 152 | Submission Open
Keywords: infertility; female infertility; in vitro fertilization; PCOS; assisted reproductive technology
(This special issue belongs to the Section Obstetrics & Gynecology)
Pancreatic Cancer: Novel Strategies of Diagnosis and Treatment submission deadline 21 Aug 2026 | 3 articles | Viewed by 5847 | Submission Open
Keywords: pancreatic cancer; chronic pancreatitis; pancreatic intraepithelial neoplasia; gastroenterology; clinical innovative diagnostic; clinical treatment strategies
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Outcomes of Glaucoma Surgery: Visual Acuity, Effectiveness and Quality of Life submission deadline 21 Aug 2026 | 4 articles | Viewed by 2226 | Submission Open
Keywords: glaucoma surgery; visual acuity; intraocular pressure; surgical outcomes; trabeculectomy; microinvasive glaucoma surgery; postoperative complications; functional vision
(This special issue belongs to the Section Ophthalmology)
Personalized Modern Oncological Strategies for Breast Cancer Treatment
edited by Vlad Alexandru Gata, Maximilian Muntean and
submission deadline 22 Aug 2026 | 3 articles | Viewed by 2547 | Submission Open
Keywords: breast cancer; targeted and immune therapies; predictive biomarkers; surgical de-escalation; MRI of the breast; breast reconstruction
(This special issue belongs to the Section General Surgery)
Advances in Plastic and Reconstructive and Aesthetic Surgery of Face, Breast and Body
edited by
submission deadline 24 Aug 2026 | 6 articles | Viewed by 15313 | Submission Open
Keywords: reconstructive surgery; academic plastic surgery; research; social media in plastic surgery; breast surgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
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