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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Rising Star: Advanced Physical Therapy and Expansion

edited by

Hyolyun Roh

submission deadline 20 Aug 2026 | 3 articles | Viewed by 4282 | Submission Open

Keywords: physical therapy; digital therapeutic technology; geriatric diseases; pediatric; psychology of physical therapies; clinical approach

(This special issue belongs to the Section Clinical Rehabilitation)

Bariatric Surgery: Challenges and Future Trends

edited by Hugo Santos-Sousa

submission deadline 20 Aug 2026 | 2 articles | Viewed by 4213 | Submission Open

Keywords: obesity; metabolic and bariatric surgery; sleeve gastrectomy; metabolic syndrome; novel surgical procedures; Nissen-sleeve fundoplication; Roux-en-Y gastric bypass distalization; single-anastomosis procedures

(This special issue belongs to the Section General Surgery)

Current Concepts and Updates in Eye Diseases

edited by Wiktor Stopyra,

Joanna Konopińska

and Anna Machalinska

submission deadline 20 Aug 2026 | 4 articles | Viewed by 4082 | Submission Open

Keywords: corneal disease; glaucoma; cataract; uveitis; ocular oncology; retinal disorder; ocular treatment; eye surgery; ocular diagnostics

(This special issue belongs to the Section Ophthalmology)

New Advances and Clinical Outcomes of Pediatric Endocrinology

edited by

Gerdi Tuli

submission deadline 20 Aug 2026 | 2 articles | Viewed by 3996 | Submission Open

Keywords: congenital hypothyroidism; rare bone diseases; growth hormone deficiency; endocrine sequelae of cancer treatments; disorders of sex development; central diabetes insipidus; gender dysphoria

(This special issue belongs to the Section Clinical Pediatrics)

Hepatobiliary Surgery: State of the Art and Future Perspectives

edited by

Teresa Perra

and

Alberto Porcu

submission deadline 20 Aug 2026 | 2 articles | Viewed by 3601 | Submission Open

Keywords: hepatobiliary surgery; cholangiocarcinoma; hepatocellular carcinoma; liver metastases; benign liver lesions

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Breakthroughs in Spine Biomechanics: Diagnostics and Treatment Approaches for Body Posture, Scoliosis and Chronic Back Pain

edited by

Maciej Rachwał

and

Joanna Baran

submission deadline 20 Aug 2026 | 2 articles | Viewed by 3487 | Submission Open

Keywords: spinal biomechanics; spinal pathologies; idiopathic scoliosis; postural abnormalities; spinal pain syndromes; spinal deformities; chronic spinal pain

(This special issue belongs to the Section Orthopedics)

Integrating Psychological Science into Chronic Pain Management: Emerging Approaches and Insights

edited by Scott G. Ravyts and Margot De Kooning

submission deadline 20 Aug 2026 | 2 articles | Viewed by 3146 | Submission Open

Keywords: chronic primary pain; nociplastic pain; coping strategies; depression; anxiety; trauma

(This special issue belongs to the Section Mental Health)

Clinical Applications of Cardiac Imaging: 2nd Edition

edited by Maria Concetta Pastore

submission deadline 20 Aug 2026 | 3 articles | Viewed by 3069 | Submission Open

Keywords: cardiac imaging; echocardiography; magnetic resonance imaging; computed tomography; nuclear imaging; heart failure; valvular heart disease; congenital heart disease

(This special issue belongs to the Section Cardiology)

Surgical Oncology: Clinical Application of Translational Medicine

edited by Domenico Parmeggiani

submission deadline 20 Aug 2026 | 3 articles | Viewed by 2832 | Submission Open

Keywords: surgical oncology; drug safety; adverse events; nanovesicles; targeted drug delivery; cancer biomarkers; precision oncology; tumor microenvironment; nanomedicine; personalized medicine; diagnostics; prognosis; innovative therapies; translational research

(This special issue belongs to the Section Oncology)

Cancer Immunotherapy: Recent Advances and Clinical Challenges

edited by

Antonello Veccia

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2792 | Submission Open

Keywords: immune checkpoint inhibitors; solid tumors; early-stage disease; metastatic disease; prognostic factors; biomarkers; resistance mechanisms

(This special issue belongs to the Section Oncology)

Breast Cancer: Symptoms, Types, Causes & Treatment

edited by Min-Jeong Cho and Sara Myers

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2737 | Submission Open

Keywords: ductal carcinoma in situ (DCIS); breast cancer; breast cancer prevention; minimally invasive surgery; innovative imaging technologies

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in the Personalized Management of Chronic Obstructive Pulmonary Disease (COPD)

edited by

Athena Gogali

and Georgios Hillas

submission deadline 20 Aug 2026 | 3 articles | Viewed by 2452 | Submission Open

Keywords: artificial intelligence; biologics; biomarkers; diagnostics; oscillometry; COPD pharmacotherapy; imaging

(This special issue belongs to the Section Respiratory Medicine)

Rehabilitation and Treatment of Post-COVID-19 Condition

edited by

Indre Bileviciute-Ljungar

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2394 | Submission Open

Keywords: post-COVID-19 condition; myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS); comorbidities; interdisciplinary; multimodal; digital medicine; rehabilitation; treatment; health-related quality of life; disability; return to work

(This special issue belongs to the Section Clinical Rehabilitation)

Non-Pharmacological Therapies and Exercise Interventions in Clinical Populations

edited by

Jorge Sánchez-Infante

submission deadline 20 Aug 2026 | 3 articles | Viewed by 2290 | Submission Open

Keywords: non-pharmacological interventions; physiotherapy approaches; physical activity; acute and chronic diseases; acute and chronic pain

(This special issue belongs to the Section Clinical Rehabilitation)

Anesthesia and Intensive Care: Clinical Practices and Prospects

edited by

Jungchan Park

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2162 | Submission Open

Keywords: artificial intelligence; clinical decision support; perioperative risk stratification; perioperative patient safety; hemodynamic optimization

(This special issue belongs to the Section Intensive Care)

Cardiovascular Prevention and Epidemiology: Innovations and Insights Bridging Research and Practice for Effective Risk Reduction

edited by

Pasquale Palmiero

and Maria Maiello

submission deadline 20 Aug 2026 | 3 articles | Viewed by 2158 | Submission Open

Keywords: cardiovascular prevention; risk reduction; epidemiology; innovations; risk stratification; population health

(This special issue belongs to the Section Cardiovascular Medicine)

Clinics and Management of Allergic and Inflammatory Skin Disorders

edited by

Andrzej Jaworek

and

Marta Szepietowska

submission deadline 20 Aug 2026 | 4 articles | Viewed by 2109 | Submission Open

Keywords: allergic dermatoses; chronic inflammatory dermatoses; atopic dermatosis; contact dermatitis; chronic urticria; rosacea; psoriasis; hidradenitis suppurativa; diagnosis; comorbidities; management

(This special issue belongs to the Section Dermatology)

New Clinical Advances in Chronic Asthma—2nd Edition

edited by Vitaliano Nicola Quaranta

submission deadline 20 Aug 2026 | 3 articles | Viewed by 1973 | Submission Open

Keywords: chronic asthma; breathlessness; coughing; inhaled corticosteroids (ICS); long-acting beta-agonists (LABAs); personalized treatment; chronic rhinosinusitis; nasal polyps; bronchiectasis; endotypes; oral corticosteroids

(This special issue belongs to the Section Respiratory Medicine)

Advances in the Diagnosis and Management of Age-Related Macular Degeneration: 3rd Edition

edited by Tsutomu Yasukawa

submission deadline 20 Aug 2026 | 3 articles | Viewed by 1910 | Submission Open

Keywords: age-related macular degeneration; angiography; anti-vascular endothelial growth factor therapy; geographic atrophy; macular neovascularization; multimodal imaging; ophthalmology; optical coherence tomography; photodynamic therapy; retinal pigment epithelium

(This special issue belongs to the Section Ophthalmology)

Musculoskeletal Pain: Clinical Management Updates

edited by

Carmen Ridao-Fernandez

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1881 | Submission Open

Keywords: musculoskeletal pain; chronic pain; gait assessment; musculoskeletal disorders; patellofemoral pain

(This special issue belongs to the Section Clinical Rehabilitation)

Enhancing and Rehabilitation of Gait and Mobility in Chronic Stroke

edited by

Maria-Arantzazu Ruescas-Nicolau

Marco Iosa

and

María Luz Sánchez-Sánchez

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1818 | Submission Open

Keywords: chronic stroke; gait rehabilitation; mobility; physical therapy; technology-assisted interventions; assessment

(This special issue belongs to the Section Clinical Neurology)

Myocarditis and Pericarditis: Clinical Advances and Current Challenges

edited by

Ankit Agrawal

and

Tom Kai Ming Wang

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1552 | Submission Open

Keywords: pericarditis; myocarditis; pericardial effusion; cardiac tamponade; interleukin-1 inhibitors; pericardium

(This special issue belongs to the Section Cardiovascular Medicine)

Advances in the Management of Cervical Spine Trauma

edited by

Jong-Beom Park

and

Sung-kyu Kim

submission deadline 20 Aug 2026 | 3 articles | Viewed by 1446 | Submission Open

Keywords: cervical spine trauma; cervical fracture; high cervical injury; subaxial injury; surgical management; occipitocervical fusion; C1 fracture; C2 fracture; spinal stability; trauma imaging; spinal cord injury; neurological outcome

(This special issue belongs to the Section Orthopedics)

Advances in Maternal–Fetal Medicine

edited by

C. Andrew Combs

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1438 | Submission Open

Keywords: maternal– fetal medicine; obstetric ultrasound; preterm birth; preeclampsia; pregnancy complications; artificial intelligence

(This special issue belongs to the Section Obstetrics & Gynecology)

New Insights into Orthodontic Treatment

edited by Federico Brugnami and Simonetta Meuli

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1366 | Submission Open

Keywords: digital orthodontics; clear aligners; artificial intelligence; digital superimpositions; cone beam computed tomography; growing patients; periodontal patients; maxillofacial surgery; long-term stability; prediction of orthodontic movements

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Endocrine Surgery: Current Treatment and Future Options

edited by Pietro Princi and

Julia Staubitz-Vernazza

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1316 | Submission Open

Keywords: endocrine surgery; thyroid surgery; parathyroid surgery; adrenal gland surgery; neuroendocrine neoplasms; thyroid cancer; thyroid cancer treatment; surgical endocrinology; robotic endocrine surgery; laparoscopic adrenalectomy; ret-roperitoneoscopic adrenalectomy; parathyroidectomy; benign thyroid disease; thyroid ablation

(This special issue belongs to the Section General Surgery)

Sepsis and Septic Shock: Diagnosis, Treatment, and Prognosis

edited by Luigi Carbone and Daniela Pugliese

submission deadline 20 Aug 2026 | 3 articles | Viewed by 1263 | Submission Open

Keywords: sepsis; septic shock; diagnosis and screening tools; risk stratification; machine learning; advanced therapies

(This special issue belongs to the Section Intensive Care)

Clinical Updates on Acromegaly

edited by

Marek Bolanowski

, Jowita Halupczok-Żyła, Aleksandra Gilis-Januszewska and Przemysław Witek

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1259 | Submission Open

Keywords: acromegaly; GH; IGH-1; growth hormone-secreting pituitary adenoma; pituitary adenoma

(This special issue belongs to the Section Endocrinology & Metabolism)

From Clinical Diagnosis to Effective Treatment of Cardiomyopathy

edited by

Sanjay Sivalokanathan

and

Łukasz A. Małek

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1150 | Submission Open

Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathy; non-ischemic cardiomyopathy; cardiac MRI; PET/CT; PET/MRI; cardiac imaging; sudden cardiac death

(This special issue belongs to the Section Cardiology)

Coronary Artery Disease in the Era of Artificial Intelligence: Clinical Insights and Therapeutic Challenges

edited by Konstantinos Mourouzis

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1083 | Submission Open

Keywords: coronary artery disease; myocardial ischemia; coronary imaging; revascularization; cardiometabolic risk; biomarkers; artificial intelligence; endothelial dysfunction; inflammation; arterial stiffness; antiplatelet therapy; heart failure; intraoperative graft verification

(This special issue belongs to the Section Cardiovascular Medicine)

Physical Therapy in Musculoskeletal Disorders: Prevention, Diagnosis, Clinical Management and Treatment—2nd Edition

edited by

Rubén Cuesta-Barriuso

submission deadline 20 Aug 2026 | 1 articles | Viewed by 990 | Submission Open

Keywords: physical therapy; musculoskeletal disorders; prevention; diagnosis; clinical management; treatment

(This special issue belongs to the Section Clinical Rehabilitation)

Advances in Trauma and Orthopedic Surgery: 3rd Edition

edited by

Christian von Rüden

submission deadline 20 Aug 2026 | 1 articles | Viewed by 983 | Submission Open

Keywords: trauma; fracture; fracture fixation; osteosynthesis; biomechanics; bone; approach; nonunion; joint replacement; outcome

(This special issue belongs to the Section Orthopedics)

New Perspectives and Innovations in Critical Illness

edited by

Francesco Alessandri

and

Giovanni Giordano

submission deadline 20 Aug 2026 | 1 articles | Viewed by 975 | Submission Open

Keywords: critical illness; intensive care; ECMO; hemodynamic management; shock physiology; cardiovascular support

(This special issue belongs to the Section Intensive Care)

Endometriosis: Advances in Diagnosis, Treatment, and Long-Term Outcomes

edited by

Francesco Martire

submission deadline 20 Aug 2026 | 1 articles | Viewed by 947 | Submission Open

Keywords: endometriosis; diagnosis and biomarkers; medical and surgical treatment; fertility and reproductive outcomes; pain management; quality of life; long-term follow-up

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Advances in Geriatric Acute Care: Multimorbidity, Frailty, and Integrated Diagnostics

edited by

Nicoletta Cerundolo

and

Carmine Siniscalchi

submission deadline 20 Aug 2026 | 3 articles | Viewed by 913 | Submission Open

Keywords: geriatric medicine; frailty; multidimensional assessment; lung ultrasound; point-of-care ultrasound; acute care of older adults; transitional care

(This special issue belongs to the Section Geriatric Medicine)

New Developments and Challenges in Assisted Reproductive Technology

edited by

Shuqin Wei

and

Justin Tan

submission deadline 20 Aug 2026 | 1 articles | Viewed by 888 | Submission Open

Keywords: assisted reproductive technology; in vitro fertilization; clinical protocols and innovations; embryo selection and evaluation; ethnicity and reproductive outcomes; live birth; cryopreservation and fertility preservation; maternal and offspring health outcomes; global perspectives in reproductive medicine

(This special issue belongs to the Section Obstetrics & Gynecology)

Updates on Neuromuscular Diseases

edited by

Menachem Sadeh

submission deadline 20 Aug 2026 | 1 articles | Viewed by 886 | Submission Open

Keywords: neuromuscualr disorders; myopathies; neuropathies; neuromuscualr junction disorders; neurogenetics

(This special issue belongs to the Section Clinical Neurology)

Clinical Perspectives on Extracorporeal Membrane Oxygenation (ECMO)

edited by

Alexander Hermann

submission deadline 20 Aug 2026 | 1 articles | Viewed by 876 | Submission Open

Keywords: extracorporeal membrane oxygenation (ECMO); extracorporeal life support (ECLS); extracorporeal cardiopulmonary resuscitation (eCPR); extracorporeal gas exchange; extracorporeal circulation; acute respiratory distress syndrome (ARDS); cardiogenic shock (CS)

(This special issue belongs to the Section Intensive Care)

Orthopaedic Trauma and Bone Healing: Recent Advances and Future Perspectives

edited by Gheorghe Tomoaia and Daniel Oltean-Dan

submission deadline 20 Aug 2026 | 1 articles | Viewed by 869 | Submission Open

Keywords: orthopaedic trauma; fractures; minimally invasive fixation; bone healing; biomaterials; periprosthetic fractures; artificial intelligence; rehabilitation; complications; orthopaedic surgery

(This special issue belongs to the Section Orthopedics)

Spine Neurosurgery: Latest Advances and Prospects

edited by Jun Jae Shin, Bong Ju Moon and Chang Kyu Lee

submission deadline 20 Aug 2026 | 1 articles | Viewed by 824 | Submission Open

Keywords: cervical spine; cervical myelopathy; ossification of the posterior longitudinal ligament (OPLL); endoscopic spine surgery; minimally invasive spine surgery; spinal deformity

(This special issue belongs to the Section Clinical Neurology)

Pharmacological Pain Management Advances

edited by Michael A. Ueberall

submission deadline 20 Aug 2026 | 1 articles | Viewed by 820 | Submission Open

Keywords: pain management; drug therapy; analgesics; co-analgesics; drug safety and drug interactions; real-world evidence

(This special issue belongs to the Section Anesthesiology)

Innovations and Challenges in the Burden and Rehabilitation of Musculoskeletal Disorders

edited by

Carla Sílvia Fernandes

and

Marta Campos Ferreira

submission deadline 20 Aug 2026 | 1 articles | Viewed by 756 | Submission Open

Keywords: musculoskeletal diseases; rehabilitation; physical therapy modalities; telemedicine; mobile applications; health information technology; patient-centered care; quality of life; health care innovation

(This special issue belongs to the Section Clinical Rehabilitation)

Endoscopic Imaging for the Diagnosis and Treatment of Gastrointestinal Diseases

edited by Mariana Jinga and

Daniel Vasile Balaban

submission deadline 20 Aug 2026 | 1 articles | Viewed by 726 | Submission Open

Keywords: endoscopy; endoscopic ultrasound; endoscopic retrograde cholangiopancreatography; artificial intelligence; diagnosis; therapy; decision making; endobiopsy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Future-Proof Care for Patients with Kidney Stones

edited by

Stijn Roemeling

and Oliver Wiseman

submission deadline 20 Aug 2026 | 2 articles | Viewed by 692 | Submission Open

Keywords: effectiveness; resilience; prevention; care pathways; urolithiasis; kidney stones; PCNL; URS; ESWL; quality of life

(This special issue belongs to the Section Nephrology & Urology)

Recent Advances in Refractive Surgery and Intraocular Lens Implantation

edited by Antonio Leccisotti

submission deadline 20 Aug 2026 | 1 articles | Viewed by 683 | Submission Open

Keywords: refractive surgery; intraocular lens implantation; keratectomy; cornea; ocular surgery; optical coherence tomography; laser surgery; KLEx (keratorefractive lenticule extraction); femtolasik

(This special issue belongs to the Section Ophthalmology)

Clinical Update on Prenatal Diagnosis and Maternal Fetal Medicine

edited by Gianluca Campobasso

submission deadline 20 Aug 2026 | 1 articles | Viewed by 668 | Submission Open

Keywords: fetal medicine; malformations; obstetric; prenatal diagnosis; artificial intelligence

(This special issue belongs to the Section Obstetrics & Gynecology)

Contemporary Coronary Intervention: Innovation, Evidence, and Patient-Centred Outcomes

edited by Kevin Liou

submission deadline 20 Aug 2026 | 1 articles | Viewed by 661 | Submission Open

Keywords: percutaneous coronary interventions; coronary imaging; coronary physiology; precision medicine; CHIP PCI; stent-less technologies; clinical outcomes; pharmacotherapy in PCI; biomarkers; artificial intelligence in PCI; sustainability in PCI

(This special issue belongs to the Section Cardiology)

Spine Surgery and Postoperative Management

edited by Mitchell K. Ng

submission deadline 20 Aug 2026 | 1 articles | Viewed by 530 | Submission Open

Keywords: spine surgery; perioperative care; enhanced recovery after surgery (ERAS); multimodal analgesia; opioid-sparing strategies; neuromonitoring; perioperative optimization

(This special issue belongs to the Section Orthopedics)

Clinical Applications and Surgical Integration of Advanced Ophthalmic Imaging

edited by Katarzyna Nowomiejska

submission deadline 20 Aug 2026 | 2 articles | Viewed by 527 | Submission Open

Keywords: ophthalmic imaging; retina; intraoperative OCT; personalized treatment; clinical applications

(This special issue belongs to the Section Ophthalmology)

Current Trends and Progress in Eating Disorders and Obesity Management

edited by Davide Gravina,

Claudia Carmassi

and

Maria Livanou

submission deadline 20 Aug 2026 | 1 articles | Viewed by 499 | Submission Open

Keywords: eating disorders; anorexia nervosa; bulimia nervosa; binge-eating disorder; ARFID; obesity; neuromodulation; biomarkers; gut microbiome; pharmacological interventions; incretin receptor agonists; GLP-1; metreleptin; psychedelics

(This special issue belongs to the Section Mental Health)

Displaying special issue 551-600 on page 12 of 31.

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