Improving Outcomes in Systemic Lupus Erythematosus: Latest Advances and Prospects in Relation to Comorbidity, Damage, and Quality of Life
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Immunology & Rheumatology".
Deadline for manuscript submissions: 30 July 2026 | Viewed by 42
Special Issue Editors
2. Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel
Interests: systemic lupus erythematosus; systemic autoimmune rheumatic diseases; lupus nephritis; cognitive impairment; comorbidities
2. Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel
Interests: systemic lupus erythematosus; systemic autoimmune rheumatic diseases; lupus nephritis
Special Issue Information
Dear Colleagues,
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease in which long-term outcomes are determined not only based on disease activity but also based on comorbidities, treatment burden, and cumulative organ damage. Despite therapeutic advances, patients continue to face major challenges, including cardiovascular disease, infection risk, and impaired quality of life. Mood disturbances, cognitive impairment, and fatigue are critical areas that patients often feel are overlooked in routine rheumatology care. Although treat-to-target strategies are emerging, they are not yet fully incorporating patient perspectives.
This Special Issue will highlight the latest advances and future prospects in improving outcomes and quality of life for people living with SLE. We welcome contributions exploring comorbidity prevention, damage accrual, infection risk and vaccination, and patient-reported outcomes. Submissions focusing on biomarkers, digital monitoring, steroid-sparing strategies, and treat-to-target approaches are also encouraged. By emphasizing outcomes that matter to both patients and clinicians, this Special Issue will inform best practice and define priorities for future research and care in SLE.
Dr. Oshrat E. Tayer-Shifman
Dr. Shaye Kivity
Guest Editors
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Keywords
- systemic lupus erythematosus
- comorbidities
- outcome measures
- damage accrual
- quality of life
- cognitive im-pairment
- infections and vaccination
- treat-to-target
- digital biomarkers
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