Challenges in Diagnosis and Treatment of Infertility—2nd Edition
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Reproductive Medicine & Andrology".
Deadline for manuscript submissions: 27 January 2026 | Viewed by 3020
Special Issue Editor
Interests: research and practice in gynecology endocrinology and medical assisted reproduction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue is the second edition of “Challenges in Diagnosis and Treatment of Infertility” (https://www.mdpi.com/journal/jcm/special_issues/233D25OURQ).
The diagnosis and treatment of infertility are challenging due to issues related to the precision required to address individual medical needs and personalized assisted reproduction applications. Age-related or gamete-depletion-related subfertility raises concerns about best practice modalities to warrant early diagnoses and prompt treatments to avoid further fertility loss or a significant reduction in patients’ chances to conceive. Lately, technical advances in preimplantation diagnostic approaches, especially via the introduction of NGS, have offered novel insights into the genetic makeup of preimplantation embryos and even the clinical exploitation of mosaic embryos. Additionally, the treatment outcomes of cell therapies and growth factors showed significant improvements in the regeneration of ovaries and the uterus following the advent of PRP therapy. Furthermore, in all cases, technological innovations such as minimally invasive or non-invasive preimplantation genetic diagnosis improved the prognosis of ART and the prospects for a wider application. It is thus important to closely monitor progress in the evaluation and treatment protocol for fertility. This Special Issue of the Journal of Clinical Medicine focuses on the recent clinical advances in fertility preservation diagnosis and treatment, as well as the improvement of prospects for the conception of and reduction in the time to pregnancy.
Prof. Dr. Konstantinos A. Zikopoulos
Guest Editor
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Keywords
- fertility
- regeneration
- age-related infertility
- preimplantation diagnosis
- precision assessment
- individualized fertility needs
- clinical diagnosis
- in vitro fertilization
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