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Heart Valve Surgery: Recent Trends and Future Perspective

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 27 July 2026 | Viewed by 709

Special Issue Editors


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Guest Editor
Department of Clinical Sciences Lund, Department of Cardiothoracic Surgery, Lund University, Skåne University Hospital, Lund, Sweden
Interests: thoracic surgery; adult cardiac surgery; minimally invasive cardiac surgery; pediatric cardiac surgery; cardiovascular surgery

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Guest Editor
Department of Clinical Sciences Lund, Department of Cardiothoracic Surgery, Lund University, Skåne University Hospital, Lund, Sweden
Interests: cardiac surgery; heart valve diseases; minimally invasive surgery; wounds; wound healing; heart failure; robotic surgery; coronary artery bypass surgery; cardiovascular surgery; atrial fibrillation

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Guest Editor
Pediatric Heart Centre, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden
Interests: electrocardiogram; echocardiography; congenital heart disease; acquired heart diseases; valve function

Special Issue Information

Dear Colleagues,

This Special Issue of Journal of Clinical Medicine will focus on current and future approaches to diagnosing and surgically treating mitral valve disease in both children and adults. Recent advancements in assessing valve function for surgical decision-making primarily have primarily relied on echocardiography, CT, and MRI to evaluate stenosis and regurgitation severity, and the introduction of 3D echocardiography has enhanced anatomical and functional assessment, yet integration with hemodynamic data remains limited. A key challenge is understanding how loading conditions affect valve function, complicating data interpretation.

Currently, the prediction of post-intervention valve function is largely subjective, relying on clinical experience. In the perioperative period, the degree of regurgitation and stenosis is often underestimated due to the impact of bypass-induced loading changes on cardiac function. Future advancements aim to integrate computer simulation modeling to objectively predict valve function under different loading conditions, offering more accurate interpretations and outcome predictions.

This Special Issue will bring together both current trends and future perspectives in mitral valve diagnostics and therapy, highlighting the need for improved assessment techniques and predictive models to enhance surgical outcomes in both pediatric and adult patients.

Dr. Per Nils J.F. Wierup
Dr. Johan Sjögren
Dr. Nina Hakacova
Guest Editors

Manuscript Submission Information

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Keywords

  • heart valve
  • diagnostics
  • surgery
  • echocardiography
  • computer simulation
  • prediction models

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Published Papers (1 paper)

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Research

14 pages, 731 KB  
Article
Unplanned Mechanical Circulatory Support as Hemodynamic Rescue Worsens Outcomes in Transcatheter Aortic Valve Replacement
by Michael Keller, Ye In Christopher Kwon, Zachary Gertz, Barbara Lawson, Mohammed Quader and Zubair A. Hashmi
J. Clin. Med. 2026, 15(6), 2371; https://doi.org/10.3390/jcm15062371 - 20 Mar 2026
Viewed by 384
Abstract
Background/Objectives: Acute hemodynamic collapse is a rare but deadly complication of transcatheter aortic valve replacement (TAVR) that can require temporary mechanical circulatory support (tMCS). Using a statewide collaborative, we conducted a focused analysis on the incidence and outcomes associated with the use [...] Read more.
Background/Objectives: Acute hemodynamic collapse is a rare but deadly complication of transcatheter aortic valve replacement (TAVR) that can require temporary mechanical circulatory support (tMCS). Using a statewide collaborative, we conducted a focused analysis on the incidence and outcomes associated with the use of tMCS during TAVR as hemodynamic rescue. Methods: We identified adult patients who underwent TAVR between September 2012 and September 2024 within the statewide collaborative and stratified them based on if tMCS was needed. Baseline patient characteristics and risk factors associated with tMCS use were analyzed as well as the impact of tMCS on outcomes. Results: We identified 7735 patients who underwent TAVR. A total of 44 (0.57%) patients required tMCS. Patients requiring tMCS were more likely to have histories that included diabetes, concurrent mitral regurgitation, prior MI, or NYHA class III or IV. These patients also experienced more emergent procedures and were more likely to require inotropic support. Patients experienced significantly worse outcomes following tMCS rescue during TAVR, with 18% requiring conversion to surgical approach (vs. 1%, p < 0.001) and 37% of tMCS patients experiencing cardiac arrest, compared to 1% of those who did not need tMCS (p < 0.001). Thirty-day mortality was worse for patients requiring tMCS (p < 0.001). MCS usage was independently associated with the need for further procedures. Conclusions: Unplanned, emergent tMCS during TAVR as hemodynamic rescue represents significant risk of complications and should be utilized judiciously in cases of acute hemodynamic collapse. Full article
(This article belongs to the Special Issue Heart Valve Surgery: Recent Trends and Future Perspective)
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