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Neuro-Psychiatric Disorders: Updates on Diagnosis and Treatment—2nd Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Mental Health".

Deadline for manuscript submissions: 31 July 2026 | Viewed by 694

Special Issue Editor

Special Issue Information

Dear Colleagues,

We are pleased to launch the 2nd edition of the Special Issue “Neuro-Psychiatric Disorders: Updates on Diagnosis and Treatment" following the great editorial achievements of its first edition.

Neuropsychiatric disorders are specific, clinically diagnosed conditions with poorly defined neurobiological bases. They greatly affect an individual's thoughts, perceptions, emotions, and/or overt behavior and may lead to loss of functioning and severe distress. Recent advances in genome research and neuroimaging have led to considerable advances in our understanding of the hereditary and acquired factors related to the etiopathology of those disorders. Hence, we are slowly starting to be able to more precisely link the underlying pathology to the overt clinical signs, helping us to provide an accurate diagnosis and an effective therapeutic plan.

This Special Issue aims to present the latest advances in the diagnostic domain and how they relate to the provision of better treatment options for the benefit of our patients.

Dr. Georgios Floros
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neuropsychiatric disorder
  • diagnosis
  • treatment
  • neurobiology
  • organic psychiatry

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Published Papers (1 paper)

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Research

16 pages, 1869 KB  
Article
Personality Disorders in Functional and Idiopathic Dystonia
by Violetta Aleksandrovna Tolmacheva, Vladimir Anatolyevich Parfenov, Dmitry Vladimirovich Romanov, Ekaterina Dmitrievna Spektor, Beatrisa Albertovna Volel and Ekaterina Vladimirovna Silina
J. Clin. Med. 2026, 15(9), 3544; https://doi.org/10.3390/jcm15093544 - 6 May 2026
Viewed by 342
Abstract
Background: Distinguishing functional dystonia (FD) from idiopathic dystonia (ID) remains a major clinical challenge because both conditions are diagnosed primarily on clinical grounds and may be accompanied by non-motor psychiatric symptoms. Although personality abnormalities have been described in functional neurological disorders, their [...] Read more.
Background: Distinguishing functional dystonia (FD) from idiopathic dystonia (ID) remains a major clinical challenge because both conditions are diagnosed primarily on clinical grounds and may be accompanied by non-motor psychiatric symptoms. Although personality abnormalities have been described in functional neurological disorders, their relevance in the differential diagnosis of dystonia remains insufficiently studied, and comparative data on FD and ID are lacking, particularly in the Russian population. Patients and Methods: A total of 178 patients with idiopathic dystonia (focal and segmental dystonia, ID) and 32 patients with functional dystonia (FD) were observed. A clinical interview by a psychiatrist was conducted; the SCID-II-PD questionnaire and the Five-Factor Personality Questionnaire (5-PFQ) were used to assess PD. Results: Patients with FD more often than patients with ID had such PD as dependent, paranoid, passive–aggressive, borderline, schizoid and schizotypal (p < 0.001), as well as obsessive–compulsive (p < 0.013) and avoidant (p < 0.049) according to SCID-II-PD. In FD, personalities of the eccentric cluster A predominate; patients with FD are characterized in personality terms by significantly greater introversion, detachment, naturalness (irresponsibility, impulsivity, carelessness), emotional restraint and practicality (conservatism, low sensitivity, rigidity) according to 5-PFQ. Conclusions: Patients with FD differ from patients with ID in both categorical and dimensional personality characteristics. The predominance of cluster A personality pathology and the identified pattern of personality-related variables may have potential value as adjunctive markers in the clinical differentiation of FD from ID. Further external validation is required before these findings can be incorporated into diagnostic algorithms. Full article
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