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New Insights in Neonatal Intensive Care

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Pediatrics".

Deadline for manuscript submissions: 15 February 2026 | Viewed by 1074

Special Issue Editors


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Guest Editor
Neonatal Intensive Care Unit, University and Hospital Trust of Verona, P.le A. Stefani 1, Verona, Italy
Interests: neonatal hemodynamics; echocardiography; lung ultrasound; neontal intensive care; pediatric cardiology, prema-turity

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Guest Editor
Intensive Care Unit, Department of Surgery, Dentistry, Maternity and Infant, University and Hospital Trust of Verona, Verona, Italy
Interests: intensive care medicine; cardiac anesthesia; echocardiography; extracorporeal membrane oxygenation; cardiovascular diseases

E-Mail
Guest Editor
Neonatal Intensive Care Unit, University and Hospital Trust of Verona, P.le A. Stefani 1, Verona, Italy
Interests: neonatal intensive care; neonate; preterm; neonatology; prematurity

Special Issue Information

Dear Colleagues,

The progress in neonatal intensive care has been remarkable in recent years, improving outcomes for even the smallest and most vulnerable infants. As advancements in neuroprotective strategies, respiratory care, hemodynamic support, point-of-care imaging, vascular access, nutrition, infection control, developmental support, etc., continue to reshape the landscape of neonatal care, our everyday challenge as clinicians and researchers is to customize evidence-based practice for individual patients to promote the best possible outcomes for premature and critically ill infants.

In this Special Issue, we welcome authors to submit papers on the advances in neonatal intensive care in terms of the understanding of pathogenesis of neonatal diseases, diagnosis, and management.

Dr. Benjamim Ficial
Dr. Leonardo Gottin
Dr. Martina Ciarcià
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neonatal intensive care
  • neonatal diseases
  • critically ill infants
  • premature infants
  • neonatal care
  • intensive care medicine

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Published Papers (1 paper)

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Research

12 pages, 234 KB  
Article
Risk Factors Associated with Postnatal Growth Velocity in Preterm Infants in a Tertiary Hospital in Northeast Mexico
by Esteban López-Garrido, Sergio Alberto Márquez-Moreno, Araní Casillas-Ramírez, Rodrigo Vargas-Ruiz, Elsa Verónica Herrera-Mayorga and Hadassa Yuef Martínez-Padrón
J. Clin. Med. 2025, 14(23), 8489; https://doi.org/10.3390/jcm14238489 - 30 Nov 2025
Viewed by 218
Abstract
Background: Suboptimal growth velocity (GV)—weight < 15 g/kg/day, head circumference (HC) < 0.9 cm/week, and length < 1 cm/week—are related to neurodevelopmental problems. Comorbidities such as sepsis, patent ductus arteriosus, bronchopulmonary dysplasia, hemodynamic instability with use of inotropes, and necrotizing enterocolitis, among [...] Read more.
Background: Suboptimal growth velocity (GV)—weight < 15 g/kg/day, head circumference (HC) < 0.9 cm/week, and length < 1 cm/week—are related to neurodevelopmental problems. Comorbidities such as sepsis, patent ductus arteriosus, bronchopulmonary dysplasia, hemodynamic instability with use of inotropes, and necrotizing enterocolitis, among others, have been related to suboptimal GV. Therefore, this study aimed to evaluate GV in preterm newborns in the Neonatal Intensive Care Unit of a tertiary-level hospital in Mexico in the first 28 days of life and determine the main factors related to suboptimal GV. Methods: This was an observational, descriptive, retrospective, and longitudinal study. Thirty-one PNBs admitted to the NICU from March 2021 to February 2023 were included. Descriptive statistics were used for neonatal characteristics and factors. They were classified into group 1 (GV < 15 g/kg/day) and group 2 (>15 g/kg/day) and compared with Fisher’s exact test. Multivariate linear regression analysis was performed for factors related to suboptimal GV. Results: Among 31 preterm infants (mean GA 30 ± 3 weeks; birth weight 1241 ± 377 g), the mean growth velocity (GV) at 28 days was 16.5 ± 10 g/kg/day for weight (optimal), while length (0.7 ± 0.4 cm/week) and head circumference (0.41 ± 0.28 cm/week) remained suboptimal. Overall, 42% showed GV < 15 g/kg/day, and 58% achieved optimal GV. Multivariate analysis revealed that apnea of prematurity (β = –9.8; p = 0.023) and birth weight < 1000 g (β = –6.3; p = 0.026) were negatively associated with GV, whereas mixed feeding (breast milk + formula) had a positive effect (β = +6.3; p = 0.008). Conclusions: The 31 PNBs studied had a mean GV of optimal weight, and a mean GV of length and HC suboptimal to that suggested by the guidelines. The degree of low birth weight (LBW) and apnea of prematurity had a negative relationship with GV, while the type of feeding showed a positive relationship (p = 0.026, 0.023, and 0.008, respectively). Full article
(This article belongs to the Special Issue New Insights in Neonatal Intensive Care)
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