Clinical Diagnosis and Treatment Strategies in Sjogren's Disease (SjD)
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Immunology & Rheumatology".
Deadline for manuscript submissions: 29 July 2026
Special Issue Editors
2. Sjögren's Clinic, University of California, San Francisco, CA, USA
Interests: Sjogren’s disease (SjD); autoimmunity; T and B Lymphocytes
2. Sjogren's Clinic, University of California, San Francisco, CA, USA
Interests: oral Sjogren's disease (SjD); pathogenesis of SjD; management of SjD oral complications
Special Issue Information
Dear Colleagues,
Sjogren’s disease (SjD) is a complex, multisystem, but often under-recognized autoimmune disease. SjD is primarily characterized by the lymphocytic infiltration of target tissues. The disease can present with diverse symptoms and signs and require a variety of clinical specialists, ranging from ocular and oral clinicians to those in neurology, pulmonology, rheumatology, and primary care.
Key to diagnosing SjD is being aware of the diverse spectrum of possible disease manifestations that can occur over a long time period, considering SJD in differential diagnosis, and connecting the dots to create a hypothesis. This hypothesis can be tested with current serology, imaging, and tissue pathology studies to diagnose SjD. In caring for patients diagnosed with SjD, it is important to include ocular and oral experts in order to prevent vision and dental damage.
The pathogenesis of SjD can involve innate and adaptive immune dysregulation, which can guide treatment strategies. Several clinical practice guidelines are available for managing SjD. However, there is not yet a regulatory-approved medication for SjD. This may soon change, as two out of several late-stage clinical development programs have successfully achieved their primary clinical outcome measures.
Prof. Dr. Nancy L. Carteron
Prof. Dr. Ava Wu
Prof. Dr. Nancy McNamara
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Sjogren
- Sjogren’s disease
- lymphocytic tissue infiltration
- interdisciplinary care
- pathogenesis
- caries
- corneal erosions
- autoimmunity
- lymphoproliferative (or lymphoma)
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
