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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Outcomes in Pediatric Neurosurgery

edited by

Petra Klinge

and Konstantina Svokos

submission deadline 20 Jul 2026 | Viewed by 271 | Submission Open

Keywords: functional outcomes; pediatric neurosurgery; quality of life; innovative technologies; global neurosurgery

(This special issue belongs to the Section Clinical Pediatrics)

Stereotactic and Functional Neurosurgery: Clinical Treatments and Future Directions

edited by

Michael G. Hart

submission deadline 20 Jul 2026 | Viewed by 269 | Submission Open

Keywords: functional neurosurgery; stereotaxy; deep brain structures; brain computer interfaces; therapeutic delivery; symptom relief

(This special issue belongs to the Section Clinical Neurology)

Current Therapeutic Approaches to Addictive Disorders

edited by Linda Haddad

submission deadline 20 Jul 2026 | Viewed by 258 | Submission Open

Keywords: addiction treatment; dependence; withdrawal management; relapse prevention; recovery; rehabilitation and support

(This special issue belongs to the Section Mental Health)

Clinical Recent Advances in the Surgical Treatment of Heart Valve Disease

edited by

Beatrice Bacchi

and Aleksander Dokollari

submission deadline 20 Jul 2026 | Viewed by 257 | Submission Open

Keywords: heart valve surgery; prosthetic valves; intervention surgery; minimally invasive and robotic surgery; valve repair and replacement

(This special issue belongs to the Section Cardiology)

Exploring Diagnostic and Therapeutic Advances in Neurodegenerative Disorders

edited by

Stefania Kalampokini

and

Effrosyni Koutsouraki

submission deadline 20 Jul 2026 | Viewed by 246 | Submission Open

Keywords: neurodegenerative disease; Parkinson’ s disease; Alzheimer’ s disease; Friedreich’ s ataxia; Huntington’ s disease; Lewy body dementia; dementia; immunosenescence; inflammaging

(This special issue belongs to the Section Clinical Neurology)

Colorectal Surgery: Current Concept and Emerging Trends

edited by

Valentin Calu

submission deadline 20 Jul 2026 | Viewed by 244 | Submission Open

Keywords: colorectal surgery; robotic surgery; neoadjuvant treatment; minimally invasive techniques; enhanced recovery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

New Clinical Insight: From Open Surgery to Minimally Invasive Foot and Ankle Surgery

edited by Enrique A. Testa and Daniel Poggio

submission deadline 20 Jul 2026 | Viewed by 239 | Submission Open

Keywords: minimally invasive surgery; foot surgery; ankle surgery; trauma surgery; orthopedic surgery; ankle arthroscopy

(This special issue belongs to the Section Orthopedics)

Advances in Clinical Practice and Personalized Approaches in Cardiovascular Disease—2nd Edition

edited by Joseph B. Selvanayagam and

Sivabaskari Pasupathy

submission deadline 20 Jul 2026 | Viewed by 231 | Submission Open

Keywords: personalized medicine; cardiovascular innovations; cardiac imaging; risk assessment; multimodal imaging; therapeutic strategies; data-driven decision making; clinical outcomes; translational research

(This special issue belongs to the Section Cardiovascular Medicine)

Colorectal Surgery: Advances in Modern Clinical Management

edited by Algimantas A. Tamelis

submission deadline 20 Jul 2026 | Viewed by 222 | Submission Open

Keywords: colorectal cancer management; surgery; complications; organ preservation; screening; colonic diverticular disease; colonic diverticulitis; hemorrhoids

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current Advances and Future Perspectives in Cardiothoracic Surgery

edited by Tomislav Kopjar

submission deadline 20 Jul 2026 | Viewed by 220 | Submission Open

Keywords: cardiothoracic surgery; minimally invasive techniques; robotic-assisted surgery; personalized therapy; surgical innovation; prosthetic devices; perioperative management; transplantation; technological advances; postoperative care; surgical outcomes; future perspectives; healthcare disparities

(This special issue belongs to the Section General Surgery)

Clinical Updates on Anesthesia and Perioperative Medicine

edited by Béla Fülesdi and

Sorin J. Brull

submission deadline 20 Jul 2026 | Viewed by 216 | Submission Open

Keywords: anesthesia; perioperative complications; residual neuromuscular block; postoperative pulmonary complications; intensive care unit acquired weakness; intensive care medicine; airway management; patient safety

(This special issue belongs to the Section Anesthesiology)

Optimizing Outcomes in Pancreato-Biliary Care: Integrating Technology, Technique, and Personalized Approaches

edited by

Andrea Tufo

submission deadline 20 Jul 2026 | Viewed by 211 | Submission Open

Keywords: pancreato-biliary care; pancreatic diseases; biliary diseases; hepato-pancreato-biliary (HPB) surgery; interventional endoscopy; interventional radiology; minimally invasive surgery; EUS-guided procedures; ERCP; personalized care/personalized medicine; multidisciplinary care; clinical outcomes; robotics and AI in PB care

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Targeting the Complement for the Treatment of Autoimmune and Neurodegenerative Diseases of the Central Nervous System

edited by Charalampos Skarlis,

Maria Anagnostouli

and

Evangelia Liouta

submission deadline 20 Jul 2026 | Viewed by 211 | Submission Open

Keywords: complement; biologics; monoclonal antibodies; neurodegenerative diseases; CNS autoimmune diseases

(This special issue belongs to the Section Clinical Neurology)

Clinical Research on Robot-Assisted Thoracic Surgery and Lung Surgery

edited by Marco Scarci

submission deadline 20 Jul 2026 | Viewed by 206 | Submission Open

Keywords: robot-assisted thoracic surgery; robotic lung surgery; minimally invasive surgery; lobectomy; segmentectomy; thoracic oncology; surgical outcomes; learning curve; clinical research; robotic technology

(This special issue belongs to the Section General Surgery)

Clinical Updates on Application of Echocardiography

edited by Aydan Ewers

submission deadline 20 Jul 2026 | Viewed by 200 | Submission Open

Keywords: echocardiography; heart failure; cardiomyopathies; cardiac echocardiography; interventional cardiology; cardiac imaging; pulmonary hypertension

(This special issue belongs to the Section Cardiology)

Corneal Diseases: Clinical Perspectives from Diagnosis to Treatment

edited by Davide Romano

submission deadline 20 Jul 2026 | Viewed by 194 | Submission Open

Keywords: cornea; keratoplasty; keratitis; keratoconus; clinical perspectives

(This special issue belongs to the Section Ophthalmology)

Gastroparesis: Emerging Insights and Endoscopic Therapeutic Strategies

edited by Sabrina Testoni

submission deadline 20 Jul 2026 | Viewed by 192 | Submission Open

Keywords: gastroparesis; gastric dismotility; gastric emptying; gastric per-oral miotomy; pyloromyotomy; gastric electric stim-ulation; botulinum toxin

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in Interventional Cardiology: From Access to Outcomes

edited by James Cotton and Benjamin Wrigley

submission deadline 20 Jul 2026 | Viewed by 191 | Submission Open

Keywords: interventional cardiology; acute coronary syndrome; chronic coronary syndrome; TAVI; TAVR; TEER; TMVR; T-TEER; TTVR; service redesign

(This special issue belongs to the Section Cardiology)

Head and Neck Surgery: Immunotherapy’s Role in Shaping Treatment Paradigms

edited by

Mark S. Swanson

submission deadline 20 Jul 2026 | Viewed by 183 | Submission Open

Keywords: head and neck surgery; otorhinolaryngology; ENT; transoral surgery; laryngeal surgery; laryngeal carcinoma; sinonasal surgery; oral cancer; oropharyngeal cancer; laryngectomy; immunotherapy; head and neck cancer; cutaneous cancer

(This special issue belongs to the Section Otolaryngology)

Therapeutic Advances in Hematological Malignancies: New Breakthroughs and Future Directions

edited by Seema Naik

submission deadline 20 Jul 2026 | Viewed by 173 | Submission Open

Keywords: leukemia; lymphoma; myeloma; cell therapy; targeted therapy

(This special issue belongs to the Section Hematology)

Contactless Magnetocardiography and Related Novel Methods for Non-Invasive Experimental and Clinical Functional Imaging of Normal and Abnormal Cardiac Electrophysiology

edited by

Riccardo Fenici

Donatella Brisinda

and

Peter Fenici

submission deadline 20 Jul 2026 | Viewed by 170 | Submission Open

Keywords: magnetocardiography; non-invasive functional imaging of cardiac electrophysiology; arrhythmogenic mechanisms; atrial fibrillation; magnetoionography; antiarrhythmic drugs; artificial intelligence

(This special issue belongs to the Section Cardiology)

Clinical Advances in Application of Echocardiography

edited by

Ramdas G. Pai

submission deadline 20 Jul 2026 | Viewed by 163 | Submission Open

Keywords: echocardiography; Doppler; transesophageal echocardiography; stain imaging; valvular hemodynamics; non valvular hemodynamics; interventional echocardiography; 3-dimensional echocardiography; tissue Doppler imaging

(This special issue belongs to the Section Cardiology)

Clinical Advances in Chronic Lymphocytic Leukemia: Focus on Elderly Frail Patients

edited by Driss Chaoui

submission deadline 20 Jul 2026 | Viewed by 156 | Submission Open

Keywords: CLL; elderly; frailty; guidelines; quality of life; IBTK; BCL2; antiCD20

(This special issue belongs to the Section Hematology)

Precision Therapies in Multiple Myeloma Management

edited by

Atsushi Satake

and Teruhito Takakuwa

submission deadline 20 Jul 2026 | Viewed by 139 | Submission Open

Keywords: multiple myeloma; precision medicine; immunotherapy; minimal residual disease (MRD); targeted therapies

(This special issue belongs to the Section Oncology)

Macular Diseases: From Diagnosis to Treatment

edited by

Gabriella De Salvo

submission deadline 22 Jul 2026 | 2 articles | Viewed by 1648 | Submission Open

Keywords: age-related macular degeneration; retinal vascular diseases; intraocular tumours; retinal imaging; OCT; OCT angiography; anti-VEGF; laser therapy; macular surgery; gene therapy; biomarkers; progression; intravitreal injections; biomarkers

(This special issue belongs to the Section Ophthalmology)

Clinical Strategies for Preventing Healthcare-Associated Infections

edited by

Monica Marilena Țânțu

Rogozea Liliana Marcela

and

Corneliu Ovidiu Vrancianu

submission deadline 24 Jul 2026 | 2 articles | Viewed by 1994 | Submission Open

Keywords: healthcare-associated infections; multidrug resistance; prevention; screening scales; polymicrobial infections; oppor-tunistic infections; sepsis

(This special issue belongs to the Section Infectious Diseases)

Psychological Affliction in Pregnancy, Delivery and Postpartum Period: A Multidisciplinary Approach

edited by

Beata Pięta

and

Edyta Barnas̈

submission deadline 24 Jul 2026 | 2 articles | Viewed by 1166 | Submission Open

Keywords: maternal mental health; pregnancy; postpartum depression; perinatal anxiety; midwifery; multidisciplinary care

(This special issue belongs to the Section Mental Health)

Recent Clinical Advances in Pelvic Organ Prolapse

edited by José Antonio García-Mejido and José Antonio Sainz-Bueno

submission deadline 24 Jul 2026 | 1 articles | Viewed by 947 | Submission Open

Keywords: pelvic organ prolapse; pelvic floor dysfunction; urogynecology; pelvic reconstructive surgery; pathophysiology of POP; surgical techniques; conservative management; patient-reported outcomes; biomaterials in pelvic surgery; levator ani muscle

(This special issue belongs to the Section Obstetrics & Gynecology)

Rewriting Metastatic Colorectal Cancer Management: Innovative Frontiers in Clinical Diagnosis and Personalized Oncology

edited by

Maria Maddalena Laterza

submission deadline 24 Jul 2026 | Viewed by 217 | Submission Open

Keywords: molecular profiling; liquid biopsy; targeted therapy; immunotherapy; biomarkers treatment; sequencing; tumor heterogeneity; personalized medicine

(This special issue belongs to the Section Oncology)

Clinical Risks and Perinatal Outcomes in Pregnancy and Childbirth: 2nd Edition

edited by Apostolos Mamopoulos and

Ioannis Tsakiridis

submission deadline 25 Jul 2026 | 6 articles | Viewed by 28131 | Submission Open

Keywords: pregnancy complications; perinatal outcomes; childbirth; hypertension; diabetes; fetal growth restriction; stillbirth; preterm delivery

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Challenges in Inflammatory Bowel Diseases

edited by

Wesley M. Raup-Konsavage

submission deadline 25 Jul 2026 | 5 articles | Viewed by 16814 | Submission Open

Keywords: ulcerative colitis; Chron’ s disease; inflammatory bowel disease; colitis-associated cancer; novel pharmaceutics

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Prevention, Diagnosis and Treatment of Oral Mucosal Diseases

edited by

Masanobu Abe

submission deadline 25 Jul 2026 | 5 articles | Viewed by 16501 | Submission Open

Keywords: oral mucosal diseases; oral mucositis; oral precancerous lesions; oral cancer; oral potentially malignant disorders; OPMDs; oral leukoplakia

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Management, Diagnosis and Treatment of Thoracic Diseases: 2nd Edition

edited by

Damiano D’Ardes

and

Andrea Boccatonda

submission deadline 25 Jul 2026 | 6 articles | Viewed by 12925 | Submission Open

Keywords: lung; thorax; pneumonia; chest; imaging; ultrasound

(This special issue belongs to the Section Respiratory Medicine)

Autism Spectrum Disorder: Diagnosis, Treatment, and Management

edited by

Marios Adamou

submission deadline 25 Jul 2026 | 3 articles | Viewed by 8527 | Submission Open

Keywords: adult autism (including autism spectrum disorders); neurodevelopmental disorders; clinical diagnostics; digital diagnostics; artificial intelligence; multimodal treatments

(This special issue belongs to the Section Mental Health)

Clinical Advances in Treatment for Venous Thromboembolism

edited by

Elisavet Grouzi

and Georgia Kaiafa

submission deadline 25 Jul 2026 | 4 articles | Viewed by 8240 | Submission Open

Keywords: venous thromboembolism; anticoagulation; cancer-associated thrombosis; thrombosis in MPNs; thrombosis in multiple myeloma; antiphospholipidic syndrome; thrombosis in PNH; thrombosis in hemoglobinopathies; thrombophilia; pregnancy and thrombophilia; reversal of anticoagulants; thromboprophylaxis

(This special issue belongs to the Section Hematology)

The Current Status and Future Directions of Pancreatoduodenectomy and Pancreatectomy

edited by

Vasileios K. Mavroeidis

Samir Pathak

and Somaiah Aroori

submission deadline 25 Jul 2026 | 5 articles | Viewed by 7194 | Submission Open

Keywords: pancreatic resection types; techniques and modifications; anastomotic techniques; open resection; minimally invasive surgery; laparoscopic resection; robotic resection; hybrid resection techniques; pancreatic resection post neoadjuvant treatment; lymphadenectomy; vascular resections; organ-sparing procedures; radicality; indications; complications

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Updates in Bleeding and Thrombotic Disorders

edited by

Hideo Wada

submission deadline 25 Jul 2026 | 2 articles | Viewed by 6439 | Submission Open

Keywords: autoimmune-acquired coagulation deficiency; acquired hemophilia A; disseminated intravascular coagulation; thrombotic microangiopathy; venous thromboembolism; acute coronary syndrome; clot waveform analysis; thrombin generation test; thromboelastogram

(This special issue belongs to the Section Hematology)

Thoracic Surgery: Updates and New Trends

edited by

Monica Casiraghi

submission deadline 25 Jul 2026 | 4 articles | Viewed by 6110 | Submission Open

Keywords: minimally invasive surgery; new technology; diagnosis; bronchoscopy; robotic system; artificial intelligence

(This special issue belongs to the Section Respiratory Medicine)

Management of Ligaments and Tendons Injuries

edited by Vivek Kumar Morya

submission deadline 25 Jul 2026 | 4 articles | Viewed by 4922 | Submission Open

Keywords: tendinopathy; ligaments; tendons; anterior cruciate ligament (ACL); rotator cuff

(This special issue belongs to the Section Orthopedics)

Clinical Advances in Spinal Neurosurgery

edited by Jang-Won Yoon

submission deadline 25 Jul 2026 | 3 articles | Viewed by 4876 | Submission Open

Keywords: minimally invasive spine surgery; lateral lumbar interbody fusion; endoscopic spine surgery; patient-reported out-comes; functional assessment; perioperative care; surgical decision-making

(This special issue belongs to the Section Clinical Neurology)

From Acute Injury to Personalized Prevention—Developing Modern Strategies

edited by

Markus Gesslein

and

Eduard Kurz

submission deadline 25 Jul 2026 | 2 articles | Viewed by 4631 | Submission Open

Keywords: orthopedics; acute injury; personalized prevention; innovative methodologies; musculoskeletal disorders; musculoskeletal injury; conservative therapy; functional testing; intervention

(This special issue belongs to the Section Orthopedics)

Endometriosis: Diagnosis and Treatment

edited by

Camran R. Nezhat

and

Ceana Nezhat

submission deadline 25 Jul 2026 | 3 articles | Viewed by 4534 | Submission Open

Keywords: endometriosis; diagnosis; video laparoscopy with and without robotic assistance; chronic pelvic pain; fertility preservation; minimally invasive surgery; biomarkers; artificial intelligence in endometriosis; adenomyosis; and adenomyoma care; multidisciplinary care; personalized medicine

(This special issue belongs to the Section Obstetrics & Gynecology)

Advancements in Individualized Plastic and Reconstructive Surgery: Second Edition

edited by

Paul Immanuel Heidekrueger

, Peter Niclas Broer and Denis C. Ehrl

submission deadline 25 Jul 2026 | 3 articles | Viewed by 3663 | Submission Open

Keywords: patient-specific reconstructive procedures; microsurgical precision techniques; autologous tissue transplantation; digital imaging and customization; biomaterials in reconstructive surgery; tissue engineering for plastic reconstruction; flap surgery innovations; personalized cleft surgery; personalized aesthetic surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Revolutionizing Neurosurgery: Cutting-Edge Techniques and Innovations

edited by

Yoichi Morofuji

submission deadline 25 Jul 2026 | 3 articles | Viewed by 3658 | Submission Open

Keywords: neuroendovascular surgery; neuroimaging; neurosurgery; neuroendoscopic surgery

(This special issue belongs to the Section Clinical Neurology)

Update on Acute Severe Respiratory Infections: 2nd Edition

edited by

Jean-Francois Timsit

submission deadline 25 Jul 2026 | 5 articles | Viewed by 3654 | Submission Open

Keywords: acute severe respiratory infection (ASRI); acute respiratory distress syndrome (ARDS); severe pneumonia; sepsis; ICU; viral respiratory infection; COVID-19; bacterial co-infection; diagnostic technology; treatment strategy; mechanical ventilation; extracorporeal membrane oxygenation (ECMO); antibiotics; non-antibiotics; pulmonary rehabilitation

(This special issue belongs to the Section Respiratory Medicine)

Innovations in Spine Care: Advancing Clinical Solutions and Emerging Technologies

edited by

Luca Ambrosio

Fabrizio Russo

, Gianluca Vadalà and Vincenzo Denaro

submission deadline 25 Jul 2026 | 2 articles | Viewed by 2778 | Submission Open

Keywords: artificial intelligence; AI; minimally invasive spine surgery; MIS; endoscopic spine surgery; intervertebral disc regeneration; precision medicine; spine care; spine fusion; osteobiologics

(This special issue belongs to the Section Orthopedics)

Diagnosis and Treatment of Aortic Dissection: Experts' Views

edited by Marja K Hedman and Annastiina Husso

submission deadline 25 Jul 2026 | 3 articles | Viewed by 2767 | Submission Open

Keywords: aortic diseases; aortic type A dissection; aortic growth rate; aortic length; aortic imaging

(This special issue belongs to the Section Cardiology)

Cardiothoracic and Vascular Anesthesia—Clinical Management and Challenges

edited by Marko Zdravković and

Vlatka Sotosek

submission deadline 25 Jul 2026 | 3 articles | Viewed by 2750 | Submission Open

Keywords: cardiac anesthesia; thoracic anesthesia; vascular anesthesia; innovation; perioperative medicine; healthcare; outcomes; challenges

(This special issue belongs to the Section Anesthesiology)

Obstructive Sleep Apnea: Advances in Clinical Diagnosis and Management

edited by

Gonzalo Labarca

submission deadline 25 Jul 2026 | 5 articles | Viewed by 2693 | Submission Open

Keywords: obstructive sleep apnea; sleep disorder breathing; central apnea; apnea– hypopnea index; precision medicine

(This special issue belongs to the Section Respiratory Medicine)

Clinical Advances in Scleral Lenses: New Insights in Lens Fitting and Customization

edited by

Daddi Fadel

and

Chelsea Bray

submission deadline 25 Jul 2026 | 1 articles | Viewed by 1964 | Submission Open

Keywords: scleral lenses; scleral lens customization; higher-order aberrations; scleral lens optics; corneoscleral profilometry; keratoconus; ocular surface diseases; dry eye; wavefront-guided correction

(This special issue belongs to the Section Ophthalmology)

Displaying special issue 401-450 on page 9 of 31.

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