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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Predictors of Response to Cancer Immunotherapy

edited by

Stephanie J. Tuminello

and

Emanuela Taioli

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3045 | Submission Open

Keywords: immunotherapy; immune checkpoint inhibitors; cancer; cancer therapy; precision medicine; survival outcomes

(This special issue belongs to the Section Molecular Immunology)

Computer Analysis for Molecular Pathological Research

edited by

Luca Zammataro

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3005 | Submission Open

Keywords: machine learning; artifical intelligence; large language models; pathology; digital pathology; multimodal learning

(This special issue belongs to the Section Molecular Informatics)

Metabolomics in Oncology

edited by

Susan Costantini

and Elena Di Gennaro

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2980 | Submission Open

Keywords: metabolome; cancer; oncology; nuclear magnetic resonance; mass spectrometry

(This special issue belongs to the Section Molecular Oncology)

Molecular Breeding of Plants: From CRISPR/Cas9 to Transcriptomics and MABc

edited by

Kwon-Kyoo Kang

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2970 | Submission Open

Keywords: CRISPR/Cas9; transcriptomics; marker-assisted breeding; genome editing; plant genetics; gene expression; plant genomics; quantitative trait loci (QTL); crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Molecular and Physiological Responses of Insects to Biotic, Abiotic and Xenobiotic Constraints

edited by

Farman Ullah

Shuo Yan

and Yaobin Lu

submission deadline 20 Oct 2025 | 3 articles | Viewed by 2865 | Submission Open

Keywords: climatic changes; chemical insecticides; insect adaptation mechanisms; resistance mechanisms; ecosystem services; insect ecology; thermal stress adaptations

(This special issue belongs to the Section Molecular Biology)

Cyclodextrins for Drug/iRNA Co-Delivery

edited by

Ivana Jarak

and

Ana Figueiras

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2854 | Submission Open

Keywords: advanced therapies; antibody-based therapies; active and passive tumor targeting; cancer; conventional chemotherapy; immune system; immunotherapy; immunotoxicity; nanomedicine; nanoparticles; nanotoxicity; tumor immune microenvironment (TIME); tumor microenvironment (TME); cyclodextrins

(This special issue belongs to the Section Macromolecules)

Microbiome Connections in Age-Related Diseases

edited by Shalini Jain

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2754 | Submission Open

Keywords: microbiome; aging; age-related diseases; Alzheimer’ s; dementia

(This special issue belongs to the Section Molecular Microbiology)

Virus-Host Interplay: Mechanisms and Novel Therapeutic Strategies

edited by

Jinsung Yang

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2752 | Submission Open

Keywords: virus; autophagy; therapeutics; virus– host interaction; virus– receptor interaction; signaling

(This special issue belongs to the Section Molecular Biology)

Research on Drug Metabolism and Disposition

edited by Tashinga E. Bapiro

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2715 | Submission Open

Keywords: drug metabolism; metabolite identification; biotransformation; clearance; bioavailability; pharmacokinetics; absorption; dose prediction; reaction phenotyping

(This special issue belongs to the Section Molecular Pharmacology)

Novel Therapeutic Strategies in Diabetes

edited by

Aikaterini Andreadi

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2701 | Submission Open

Keywords: diabetes mellitus; type 1 and type 2 diabetes; GLP1-RA; SGLT2i; smart pen and CSII; micro and macrovascular complications; cardiovascular risk; diabetic foot

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research on Mitochondrial Genetics and Epigenetics

edited by Arianna Montanari

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2668 | Submission Open

Keywords: mitochondrial DNA dynamics; retrograde regulation; epigenetic modulators; mitochondrial diseases; cellular homeostasis

(This special issue belongs to the Section Molecular Biology)

Crop Biotic and Abiotic Stress Tolerance: 4th Edition

edited by

Fazhan Qiu

submission deadline 20 Oct 2025 | 4 articles | Viewed by 2663 | Submission Open

Keywords: biotic and abiotic stress tolerance; QTL/gene mapping and clones; gene editing; marker-assisted selection; genomic breeding

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Iodinated Compounds and Molecular Iodine in Human Disease

edited by

Carmen Aceves

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2625 | Submission Open

Keywords: iodine; iodinated compounds; oxidized iodine; oxidized iodine supplement

(This special issue belongs to the Section Biochemistry)

Structural and Functional Insights into Membrane Transporters: A Tribute to Dr. Ernest Wright

edited by Jeff Abramson

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2618 | Submission Open

Keywords: membrane transporters; membrane protein; glucose transport; cell membrane; interface reaction

(This special issue belongs to the Section Molecular Biology)

Molecular Research on Neuroinflammation and Brain Aging

edited by

Stephen C. Bondy

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2597 | Submission Open

Keywords: neurotoxicology; aging; Alzheimer's disease; neurodegenerative diseases; inflammatory

(This special issue belongs to the Section Molecular Toxicology)

Molecular Signatures in Autism Spectrum Disorders

edited by

Nikolay Mehterov

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2588 | Submission Open

Keywords: epigenetics; ncRNA; mRNA; cytokines; mitochondria; inflammation; autism

(This special issue belongs to the Section Molecular Neurobiology)

Advanced Molecular Research in Benign and Malignant Lung Disease

edited by Biniam Kidane

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2564 | Submission Open

Keywords: benign lung disease; lung cancer; molecular biology; inflammation; metastasis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Signaling in Respiratory Diseases

edited by Tonio Pera

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2563 | Submission Open

Keywords: asthma; COPD; cystic fibrosis; GPCR; pharmacology; inflammation; airway remodeling

(This special issue belongs to the Section Molecular Biology)

Medicinal Mechanisms of Biologically Active Compounds in Cancer

edited by

Karthik Gourishetti

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2542 | Submission Open

Keywords: biologically active compounds; cancer treatment; apoptosis; tumor growth; natural products; oxidative stress

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advancing Occupational Health Through Omics Technologies

edited by

Silvia Vivarelli

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2468 | Submission Open

Keywords: omics technologies; occupational health; biomarkers; personalized risk assessment; workplace exposures; genomics; proteomics; psychosocial factors; disease susceptibility; preventive medicine

(This special issue belongs to the Section Molecular Biology)

Molecular Perspective in Autoimmune Diseases

edited by Andrés González-García and

Montserrat Fernández-Guarino

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2440 | Submission Open

Keywords: interferon; cytokines; lupus nephritis; lupus; type I interferon; vasculitis; IgG4-related disease; B cell; NETs; IL-6; biomarkers

(This special issue belongs to the Section Molecular Immunology)

Latest Advances in Cytokine Storm

edited by

Raymond Kaempfer

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2439 | Submission Open

Keywords: cytokine storm; cytokine release syndrome; inflammatory; protective immunity; multi-drug resistant bacterial strains

(This special issue belongs to the Section Molecular Immunology)

Prostate Diseases: Focus on Hormone Therapies and Targeted Interventions

edited by Gabriel Campolina-Silva and Héctor Contreras

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2423 | Submission Open

Keywords: urinary disease; prostate cancer; hormone; therapeutic strategy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in the 3D Culture Systems and Organoids for Disease Modeling and Therapeutics

edited by Su-Yun Lyu

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2399 | Submission Open

Keywords: 3D culture systems; organoids; disease modeling; drug discovery; regenerative; medicine biomaterials; molecular mechanisms; cancer; immunology; personalized medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pathogenesis, Biomarkers and Therapeutic Perspectives of Ocular Diseases

edited by

Eugenia Piragine

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2329 | Submission Open

Keywords: ocular diseases; dry eye; glaucoma; diabetic retinopathy; macular degeneration; molecular mechanisms; diagnosis; preclinical research; clinical studies; drug therapy; pharmacology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Latest Advances in Comparative Genomics

edited by

Candice Brinkmeyer-Langford

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2326 | Submission Open

Keywords: genetics; genomics; evolution; phylogeny; sequencing; variation; conservation

(This special issue belongs to the Section Molecular Informatics)

Advances in Sepsis: Pathogenesis, Biomarkers, Treatments and Prognosis

edited by Francesca Innocenti

submission deadline 20 Oct 2025 | 3 articles | Viewed by 2314 | Submission Open

Keywords: sepsis phenotypes; hemodynamic stabilization; fluids; vasopressors; diagnostic biomarkers; tailored approach; immune modulation; immunomodulatory therapy; prognostic stratification

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bioactive Food Compounds in the Prevention and Treatment of Non-Communicable Diseases

edited by

Aneta Kopeć

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2299 | Submission Open

Keywords: bioactive compounds; dietary fiber; polyphenols; sulfur compounds; antioxidant; reduce oxidative stress; inflammation; non-communicable diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Stem Cells in Tissue Engineering

edited by Ichiro Takada

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2291 | Submission Open

Keywords: stem cells; transcription factors; transcription co-regulators; chromatin remodeling factors; chromatin receptors; nuclear maintenance and differentiation; iPS cells; iPS-T/NK; tissue engineering

(This special issue belongs to the Section Molecular Biology)

Ceramides and Ceramide Kinase

edited by Antonio Gomez-Muñoz

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2280 | Submission Open

Keywords: cancer; cell survival; ceramides; ceramide 1-phosphate; inflammation

(This special issue belongs to the Section Biochemistry)

Molecular Advances in Analytical Techniques for Biological and Medical Research: 2nd Edition

edited by

Angela Di Capua

and

Maria Assunta Acquavia

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2276 | Submission Open

Keywords: HPLC; GC; electrophoresis; mass spectrometry; plant materials; validation; metabolomics; proteomics; protein– ligand interaction.

(This special issue belongs to the Section Molecular Biology)

Lymphedema: From Mechanism to Treatment

edited by

Florent Morfoisse

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2250 | Submission Open

Keywords: lymphedema; lymphatic dysfunction; molecular mechanisms; cell signaling; diagnostic imaging; biomarkers; therapeutic interventions; inflammation; adipose tissue accumulation; fibrosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Latest Advances in Protein-Ligand Interactions

edited by

Fabio Altieri

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2214 | Submission Open

Keywords: protein– ligand interaction; molecular mode of actions; target identification; drug discovery; bioactive agents

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Advances in the Synthesis and Medical Application of Biomaterials

edited by

Csaba Balázsi

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2205 | Submission Open

Keywords: nanostructured biomaterials; bioceramics; bioactive; biodegradable; resorbable materials; biomimetic materials; biocompatibility

(This special issue belongs to the Section Materials Science)

Non-Coding RNA: Biomarkers for Cardiovascular Diseases

edited by

Isabel Moscoso

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2186 | Submission Open

Keywords: cardiovascular diseases; non-coding RNA (ncRNA); therapeutics; biomarkers; microRNA; lncRNA; siRNA

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Molecular Basis of Extracellular Vesicles in Health and Diseases—2nd Edition

edited by Taral R. Lunavat

submission deadline 20 Oct 2025 | 2 articles | Viewed by 2091 | Submission Open

Keywords: exosomes; microvesicles; extracellular vesicles; genetic material; therapeutics; diagnostics; biomarkers; molecular pathway; liquid biopsy; metabolism; omics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Functional Nanomaterials and Nanocomposites for Biomedical Application

edited by Gi Doo Cha

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2087 | Submission Open

Keywords: nanomaterials; nanocomposites; biomedicine; metal nanoparticles; drug delivery; bioelectronics

(This special issue belongs to the Section Molecular Nanoscience)

Multi-Omics Approaches to Disentangle Pathomechanisms in Neurological Disease

edited by

Francesco Pezzini

and

Stefano Doccini

submission deadline 20 Oct 2025 | 3 articles | Viewed by 2058 | Submission Open

Keywords: neurological diseases; molecular mechanisms; neurodegeneration; omics; bioinformatics; disease biomarkers; biochemical pathways; diagnostic and therapeutic targets

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Insights into Microbial Dynamics in Agroforestry for Resilience and Climate Adaptation

edited by

Amrita Chakraborty

and

Amit Roy

submission deadline 20 Oct 2025 | 1 articles | Viewed by 2054 | Submission Open

Keywords: agroforestry; soil microbes; plant-microbe interactions; microbial influence; microbiomes; insect-microbe interactions; horizontal gene transfer

(This special issue belongs to the Section Molecular Plant Sciences)

COVID-19: Molecular Research and Novel Therapy

edited by

Mihaela Chivu-Economescu

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1986 | Submission Open

Keywords: SARS-CoV-2; virus-host interaction; immune response; antiviral agents; vaccines

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Insights into Microglia Heterogeneity and Neurodegeneration

edited by

Maria Anttonietta Panaro

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1915 | Submission Open

Keywords: microglia; synapses; stress; aging; heterogeneity; CNS; single-cell RNA sequencing; neurodegenerative diseases

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Research on Chronic Kidney Disease

edited by

Sohel Julovi

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1904 | Submission Open

Keywords: CKD; CVD; CKD-MBD; oxidative stress; inflammation; fibrosis; biochemical markers

(This special issue belongs to the Section Molecular Biology)

Regulation of Ion Channels and Transporters

edited by

Susumu Ohya

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1902 | Submission Open

Keywords: ion channels; ion transporters; cardiovascular disease; inflammatory disease; cancers; neurogenerative disease; disease microenvironment; drug discovery; drug resistance

(This special issue belongs to the Section Molecular Biology)

Advances and Insights in Tumorigenesis and Tumor Metastasis

edited by

Sayem Miah

and

Mohammad Rahman

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1875 | Submission Open

Keywords: tumorigenesis; metastasis; biomarkers

(This special issue belongs to the Section Molecular Oncology)

Molecular Insights into Addiction

edited by

Aleksandra Suchanecka

and

Jolanta Chmielowiec

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1783 | Submission Open

Keywords: addiction; dependence; neurobiology; reward; neuroplasticity; biostatistics

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Cancer Stem Cells and Tumor Microenvironment

edited by Shaoguang Li

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1748 | Submission Open

Keywords: cancer stem cells; tumor microenvironment; tumor initiation; tumor progression; chemoresistance

(This special issue belongs to the Section Molecular Oncology)

Latest Review Papers in Physical Chemistry and Chemical Physics 2024

edited by

Victor Borovkov

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1746 | Submission Open

Keywords: heterogeneous structures; alignment and surface phenomena; quantum theory; statistical and classical mechanics; molecular structure; chemical kinetics; dynamics; kinetics; photochemistry; spectroscopy

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Bioactive Compounds of Natural Origin: 2nd Edition

edited by

Katarzyna Pacyga

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1739 | Submission Open

Keywords: plants; extraction methods; bioactive compounds; natural products; application

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Systemic and Mucosal Inflammation in Colorectal Cancer: Underlying Factors, Significance, and Related Biomarkers, 2nd Edition

edited by

Paola Sena

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1665 | Submission Open

Keywords: molecular changes; colorectal cancer; normal mucosa; apoptotic proteins; inflammatory mechanism; adenoma– carcinoma sequence; cancer biomarkers

(This special issue belongs to the Section Molecular Oncology)

Exploring Amazon Bioactives: Novel Anti-Pathogen Therapeutics and Pharmaceutical Breakthroughs

edited by Marta Chagas Monteiro,

Nélio Teixeira Machado

and Pedro Roosevelt Romão

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1664 | Submission Open

Keywords: waste biomass; thermochemical processes; bio-oils; phenolic compounds; anti-inflammatory actions; antiviral mechanisms; cancer; cytokine/chemokine regulation; inflammatory conditions/diseases; innate immunity; immune response; immunomodulatory and anti-infective effects; immunomodulation; immunotoxicology; medicinal chemistry; neglected tropical diseases; parasitic disease; purinergic signaling

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Displaying special issue 151-200 on page 4 of 68.

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