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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Molecular Progression of Movement Disorders

edited by

Michał Latalski

and

Pilar Gomez-Garre

submission deadline 20 May 2026 | 3 articles | Viewed by 3466 | Submission Open

Keywords: movement disorders; molecular mechanisms; neurodegenerative diseases; therapeutic targets; biomarkers; neuroinflammation; protein misfolding; mitochondrial dysfunction; environmental factors; genetic factors

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bioactive Food Compounds in the Prevention and Treatment of Non-Communicable Diseases

edited by

Aneta Kopeć

submission deadline 20 May 2026 | 2 articles | Viewed by 3455 | Submission Open

Keywords: bioactive compounds; dietary fiber; polyphenols; sulfur compounds; antioxidant; reduce oxidative stress; inflammation; non-communicable diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

New Insights into Kidney Diseases—2nd Edition

edited by

Kan Katayama

submission deadline 20 May 2026 | 3 articles | Viewed by 3454 | Submission Open

Keywords: kidney disease; focal segmental glomerulosclerosis; genetic kidney disease; minimal change disease; nephrotic syndrome; podocyte

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Eukaryotic DNA Replication—from Bench to Bedside

edited by Heinz-Peter Nasheuer

submission deadline 20 May 2026 | 1 articles | Viewed by 3438 | Submission Open

Keywords: genome stability; cell cycle; DNA replication; chromatin replication; replication origins— selection; licensing and firing; replication forks— smoothly progressing and under stress; role of DNA replication in cancer and other human diseases; disease treatment opportunities

(This special issue belongs to the Section Molecular Genetics and Genomics)

Latest Research in Alzheimer’s Disease

edited by

Prashant R Bharadwaj

submission deadline 20 May 2026 | 4 articles | Viewed by 3425 | Submission Open

Keywords: Alzheimer’ s disease; neurodegenerative disease; disease diagnosis; biomarker development; drug development; disease models

(This special issue belongs to the Section Molecular Neurobiology)

Osteoblast Differentiation in Human Health and Disease

edited by

Younho Han

submission deadline 20 May 2026 | 2 articles | Viewed by 3304 | Submission Open

Keywords: osteoblast differentiation; bone remodeling; mesenchymal stem cells; skeletal diseases; osteogenesis; bone mineralization; osteoporosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cell Organelle Stress Responses and Implications in Human Diseases

edited by

Jaeseok Han

submission deadline 20 May 2026 | 2 articles | Viewed by 3206 | Submission Open

Keywords: organelle stresses; mitochondria; ER; lysosome; human diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Advances of Free-Radical Reactions in Organic Chemistry

edited by

José Justicia

submission deadline 20 May 2026 | 2 articles | Viewed by 3174 | Submission Open

Keywords: free-radical reactions; organic chemistry; organic synthesis; fotoredox reactions; organometallics reactions; computational calculations; free radicals in biology; free radicals in green chemistry

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

mRNA/miRNAs Network in Diabetes and Its Complications

edited by

Daniela Lixandru

submission deadline 20 May 2026 | 2 articles | Viewed by 3172 | Submission Open

Keywords: RNA/miRNAs; exosomes; regenerative medicine; translational medicine; adipose tissue biology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Antimicrobial Agents: Synthesis and Design

edited by

Silvana Alfei

submission deadline 20 May 2026 | 1 articles | Viewed by 3152 | Submission Open

Keywords: multi-drug resistant Gram-negative and Gram-positive pathogens; clinically relevant superbugs; severe and almost untreatable infections; immunocompromised individuals; synthetic antimicrobial cationic macromolecules; synthetic cationic dendrimers; polymers; and copolymers; polymerizing strategies; quaternary ammonium and phosphonium salts; amino-acid modified macromolecules; electrostatic interactions and membrane permeabilization; membrane disruptors; drug delivery systems; cationic bola-amphiphiles

(This special issue belongs to the Section Molecular Microbiology)

Molecular Pathophysiology and Treatment of Coronary Artery Disease

edited by

Kazufumi Nakamura

submission deadline 20 May 2026 | 2 articles | Viewed by 3049 | Submission Open

Keywords: coronary artery disease; ischemic cardiomyopathy; immune-related adverse events; CAD associated with autoimmune diseases; coronary artery disease-related cardiomyopathy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Pathophysiology of Myocardial Disease, 2nd Edition

edited by

Ryan D. Sullivan

Inna P. Gladysheva

and Hongyu Qiu

submission deadline 20 May 2026 | 1 articles | Viewed by 3049 | Submission Open

Keywords: myocardial disease; cardiomyopathy; fibrosis and remodeling; inflammation; hypertension; heart failure; cardiometabolic; cardio-renal; heart-liver axis; comorbidity; molecular mechanisms; pathophysiology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Environmental Stress-Induced Human Diseases

edited by

Silvia Cantara

submission deadline 20 May 2026 | 1 articles | Viewed by 2947 | Submission Open

Keywords: environmental stress; oxidative stress; inflammation; epigenetic modifications; DNA damage and repair; cellular signaling pathways; mitochondrial dysfunction; autophagy; air pollution; heavy metal toxicity; endocrine disruptors; climate change and health; neurodegeneration; cancer biology; immune system dysregulation; gene– environment interactions; biomarkers of exposure and disease; systems biology; translational research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research on Artificial Intelligence in Plant Biology

edited by Haopeng Yu

submission deadline 20 May 2026 | 2 articles | Viewed by 2896 | Submission Open

Keywords: artificial intelligence; plant biology; RNA regulation; DNA regulatory elements; plant development; plant biotechnology

(This special issue belongs to the Section Molecular Plant Sciences)

Application of Electrochemical Materials in Molecular Biology

edited by

Robert Ziółkowski

submission deadline 20 May 2026 | 1 articles | Viewed by 2854 | Submission Open

Keywords: electrochemistry; (bio)analytical chemistry; molecular biology; point-of-care; nanomaterials; (bio)molecules

(This special issue belongs to the Section Materials Science)

Emerging Roles of the Gut-Brain Axis (GBA) in Health and Disease

edited by Vinata Vedam-Mai

submission deadline 20 May 2026 | 2 articles | Viewed by 2685 | Submission Open

Keywords: gut– brain axis; gut microbiota; brain function; diagnostic tools

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Genomics Advances in Behaviours

edited by

Péter Pikó

submission deadline 20 May 2026 | 1 articles | Viewed by 2678 | Submission Open

Keywords: unhealthy and healthy behaviors; smoking; sleeping; eating; alcoholism; gambling; aggression; addictive behaviors; physical activity; mental disorders

(This special issue belongs to the Section Molecular Biology)

Emerging Biomaterials for Cartilage Regeneration

edited by

Valentina Vassallo

submission deadline 20 May 2026 | 1 articles | Viewed by 2599 | Submission Open

Keywords: osteoarthritis; glycosaminoglycans; biomaterials; cartilage regeneration; mesenchymal cells; chondrocytes

(This special issue belongs to the Section Biochemistry)

Molecular Research on Ataxia

edited by

Jose Miguel Laffita-Mesa

submission deadline 20 May 2026 | 2 articles | Viewed by 2584 | Submission Open

Keywords: ataxia; molecular mechanisms; repeat expansion disorders; gene discovery; biomarkers; RNA biology; protein aggregation; epigenetics; gene therapy; neurodegeneration

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Sleep and Breathing: From Molecular Perspectives

edited by Alberto Alonso-Fernández

submission deadline 20 May 2026 | 1 articles | Viewed by 2580 | Submission Open

Keywords: obstructive sleep apnea; cardiovascular risk; cardiovascular diseases/physiopathology; continuous positive airway pressure; hypertension; biomarkers; diabetes; pregnancy; gene expression profiling; genetic markers; inflammation mediators; oxidative stress; proteomics

(This special issue belongs to the Section Molecular Biology)

Applications of Phytochemicals in Drug Synthesis

edited by

Gregorio Peron

submission deadline 20 May 2026 | 1 articles | Viewed by 2570 | Submission Open

Keywords: natural products; phytochemistry; chemical synthesis; drugs; medicinal plants; natural sources; byproducts

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Endoplasmic Reticulum Stress and Apoptosis—Second Edition

edited by

Orsolya Kapuy

and

Beáta Lizák

submission deadline 20 May 2026 | 2 articles | Viewed by 2569 | Submission Open

Keywords: ER stress; apoptosis initiated by ER stress; cellular survival; redox homeostasis of ER; autophagy initiated by ER stress; cell death pathways initiated by ER stress

(This special issue belongs to the Section Biochemistry)

Molecular Targets and Mechanisms of Innovative Therapies and Natural Adjuvants in Glioblastoma Management

edited by

Maria Grazia Bottone

and Fabrizio De Luca

submission deadline 20 May 2026 | 2 articles | Viewed by 2543 | Submission Open

Keywords: glioblastoma; targeted therapy; traditional and emerging therapies; signaling pathways; tumor microenvironment

(This special issue belongs to the Section Molecular Oncology)

Molecular Research Advances in Metabolic Syndrome

edited by

Phileno Pinge-Filho

submission deadline 20 May 2026 | 1 articles | Viewed by 2503 | Submission Open

Keywords: metabolic syndrome; sepsis; molecular mechanisms; inflammation; insulin resistance; cardiovascular parameters; immune– metabolic crosstalk; experimental models; biomarkers; therapeutic targets

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Advances in Reversing Cancer Therapy Resistance

edited by

Tae Woo Kim

submission deadline 20 May 2026 | 3 articles | Viewed by 2423 | Submission Open

Keywords: cancer; natural compound; cell death; radioresistance; chemoresistance

(This special issue belongs to the Section Molecular Pharmacology)

Challenges of Acute Ischemic Stroke

edited by

Marta Iacobucci

submission deadline 20 May 2026 | 1 articles | Viewed by 2382 | Submission Open

Keywords: stroke; endovascular treatment; intravenous thrombolysis; futile recanalization; microvascular therapy

(This special issue belongs to the Section Molecular Neurobiology)

Neural Stem Cells: Latest Applications and Future Perspectives

edited by

Evangelos Delivopoulos

submission deadline 20 May 2026 | 1 articles | Viewed by 2376 | Submission Open

Keywords: neural differentiation; embryonic stem cells; neural stem cells; neural progenitor cells; neuropathology; neurological disease

(This special issue belongs to the Section Molecular Biology)

Cell Death in Human Diseases: Mechanisms, Biomarkers and Therapeutic Opportunities

edited by

Decha Pinkaew

submission deadline 20 May 2026 | 2 articles | Viewed by 2361 | Submission Open

Keywords: cell death; apoptosis; necroptosis; ferroptosis; pyroptosis; human disease; biomarkers

(This special issue belongs to the Section Molecular Biology)

Molecular and Physiological Analysis of Stress in Plants

edited by

Yong Li

submission deadline 20 May 2026 | 1 articles | Viewed by 2336 | Submission Open

Keywords: plant stress; biotic stress; abiotic stress; stress response; gene expression; epigenetic stress memory; ABA; SA

(This special issue belongs to the Section Molecular Plant Sciences)

Latest Molecular Advances in Prostate Cancer

edited by Rejane Maira Góes

submission deadline 20 May 2026 | 2 articles | Viewed by 2334 | Submission Open

Keywords: prostate cancer; androgen signaling; metabolic reprogramming; tumor microenvironment; inflammation; immunotherapy; chemoprotection; phytotherapy

(This special issue belongs to the Section Molecular Oncology)

Unraveling Neuroimmune Disorders: From Pathogenic Pathways to Biomarker-Driven Precision Medicine

edited by

Mariapaola Marino

submission deadline 20 May 2026 | 2 articles | Viewed by 2290 | Submission Open

Keywords: innate immunity; adaptive immunity; inflammation; autoantibodies; peptides; cytokines; receptors; leukocytes; extracellular vesicles; signal transduction; apoptosis

(This special issue belongs to the Section Molecular Immunology)

Toxicants and Their Effects on Innate Immune Function and Inflammatory Response

edited by

James M. Harper

submission deadline 20 May 2026 | 1 articles | Viewed by 2207 | Submission Open

Keywords: ecotoxicology; innate immunity; inflammation; pesticides; plasticizers; pattern-recognition receptors

(This special issue belongs to the Section Molecular Toxicology)

Molecular Pharmacology of Cation-Permeable Ion Channels

edited by

Jian Shi

submission deadline 20 May 2026 | 2 articles | Viewed by 2198 | Submission Open

Keywords: cation-permeable ion channel structure; cation-permeable ion channel functions; cation-permeable ion channel pharmacology; cation-permeable ion channel and diseases; innovative techniques for cation-permeable ion channel research

(This special issue belongs to the Section Molecular Pharmacology)

G Protein-Coupled Receptor Signaling and Regulation, 2nd Edition

edited by

Vsevolod V. Gurevich

submission deadline 20 May 2026 | 2 articles | Viewed by 2123 | Submission Open

Keywords: GPCRs; signaling; trafficking; G proteins; arrestins; RGS proteins; GRKs

(This special issue belongs to the Section Biochemistry)

Structural Characterization and Pharmacological Activity of Natural Compounds

edited by

Ana Amić

submission deadline 20 May 2026 | 1 articles | Viewed by 2115 | Submission Open

Keywords: natural compounds; bioactive molecules; molecular structure; characterisation; pharmacological activity; biochemical properties; pharmacokinetics; toxicity

(This special issue belongs to the Section Molecular Pharmacology)

Survival of the Fittest: Physiological Adaptations of Insects in Hostile Environments

edited by

Amit Roy

and

Amrita Chakraborty

submission deadline 20 May 2026 | 2 articles | Viewed by 2111 | Submission Open

Keywords: insect adaptation; temperature tolerance; insect physiology; detoxification; symbiosis and stress tolerance mechanisms

(This special issue belongs to the Section Molecular Biology)

Synthesis, Biosynthesis and Implications of Chalcones

edited by

Pal Perjesi

submission deadline 20 May 2026 | 2 articles | Viewed by 2108 | Submission Open

Keywords: chalcones; biosynthesis; biochemistry

(This special issue belongs to the Section Biochemistry)

Stress-Activated Molecular Remodeling: Lipids, Chaperones, and the Cytoskeleton

edited by

Nikolas Nikolaidis

submission deadline 20 May 2026 | 3 articles | Viewed by 2105 | Submission Open

Keywords: cellular stress response; molecular remodeling; lipid signaling; membrane dynamics; cytoskeletal reorganization; chaperones; heat shock proteins; proteostasis; membrane– protein interactions; stress-induced trafficking; mechano-transduction; cell survival signaling

(This special issue belongs to the Section Molecular Biology)

Aquatic Organisms Models Dedicated to Disease

edited by

Malgorzata Kloc

and

Jacek Z. Kubiak

submission deadline 20 May 2026 | 2 articles | Viewed by 2011 | Submission Open

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Natural Products for Cancer Therapy: Mechanisms, Synergies, and Clinical Applications

edited by

Qibiao Wu

and Hiu Yee Kwan

submission deadline 20 May 2026 | 1 articles | Viewed by 2010 | Submission Open

Keywords: natural products; cancer therapy; traditional Chinese medicine (TCM); integrative medicine; cancer drug resistance; antitumor mechanisms; molecular targeting; drug synergy; clinical application

(This special issue belongs to the Section Molecular Oncology)

DNA Replication, Damage and Repair in Repeat Instability: Their Role from Bacteria to Genetic Disorders in Humans

edited by

Enrique Viguera

submission deadline 20 May 2026 | 1 articles | Viewed by 1987 | Submission Open

Keywords: DNA repeat instability; DNA replication; DNA damage; DNA repair; tandem repeats; trinucleotide repeats; repeat expansion diseases; microsatellite instability; replication slippage; phenotypic variability; bacteria; genetic disorders

(This special issue belongs to the Section Molecular Genetics and Genomics)

Pancreatic Diseases: Molecular Pathology and Therapeutics

edited by

Maria Ines Vaccaro

submission deadline 20 May 2026 | 1 articles | Viewed by 1968 | Submission Open

Keywords: pancreatic cancer; acute pancreatitis; chronic pancreatitis; diabetes; inflammation; molecular markers; therapeutic strategies; genetic predispositions; diagnostic tools

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Synthesis Manufacturing and Biomedical Applications of Nanofibers Scaffold

edited by

Marco Antonio Álvarez Pérez

and

Vincenzo Guarino

submission deadline 20 May 2026 | 1 articles | Viewed by 1944 | Submission Open

Keywords: scaffold manufacturing; nanofibers; 3D platforms; biohybrid scaffolds; biomolecules; functionalization; biomaterials

(This special issue belongs to the Section Molecular Nanoscience)

Melanoma: From Molecular Mechanisms to Therapeutics

edited by Dorota Ciołczyk-Wierzbicka

submission deadline 20 May 2026 | 1 articles | Viewed by 1842 | Submission Open

Keywords: melanoma; molecular mechanism; signaling pathways; genetic mutations; cancer therapy/treatment; drug resistance

(This special issue belongs to the Section Molecular Oncology)

Intrinsically Disordered Proteins (IDPs): From Structure to Mechanism and Function

edited by

Kyouhoon Han

submission deadline 20 May 2026 | 1 articles | Viewed by 1806 | Submission Open

Keywords: IDP; NMR; completely unstructured; pre-structured; PreSMo; target binding

(This special issue belongs to the Section Biochemistry)

Microbiome in Cancer: From Pathogenesis to Therapeutic Innovation

edited by

Francesca Benedetti

and

Davide Zella

submission deadline 20 May 2026 | 1 articles | Viewed by 1798 | Submission Open

Keywords: microbiome; cancer; anticancer drugs; chemoresistance; immune modulation

(This special issue belongs to the Section Molecular Microbiology)

Acute Leukemia: From Basic Research to Clinical Application, Second Edition

edited by

Luca Lo Nigro

submission deadline 20 May 2026 | 3 articles | Viewed by 1791 | Submission Open

Keywords: acute lymphoblastic leukemia (ALL); acute myeloid leukemia (AML); genomic findings; post-genomic findings; targeted therapies; immunotherapies; novel markers

(This special issue belongs to the Section Molecular Oncology)

Mitochondria as a Therapeutic Target for Anti-Cancer Drugs

edited by

Dalia Marija Kopustinskiene

submission deadline 20 May 2026 | Viewed by 1703 | Submission Open

Keywords: mitochondria; cancer; apoptosis; oxidative phosphorylation; Warburg effect; cardiolipin; inflammation

(This special issue belongs to the Section Molecular Oncology)

Cardiomyopathy: From Molecular Pathology to Treatment

edited by

Andrea Sonaglioni

and

Gian Luigi Nicolosi

submission deadline 20 May 2026 | 2 articles | Viewed by 1659 | Submission Open

Keywords: obesity; myocardial fibrosis; subclinical myocardial dysfunction; fibrotic remodeling; microRNAs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Research in Nanophotonics and Biophotonics

edited by

Prabhakar Pradhan

submission deadline 20 May 2026 | 1 articles | Viewed by 1647 | Submission Open

Keywords: biophotonics; spectroscopy; light scattering; Raman/FTIR; cancer; Alzheimer's and Parkinson’ s diseases; nanophotonics; plasmonics; nano-biophotonics

(This special issue belongs to the Section Molecular Nanoscience)

Displaying special issue 151-200 on page 4 of 68.

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