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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Research on the Growth and Development of Germ Cells
edited by
submission deadline 20 Sep 2024 | Viewed by 383 | Submission Open
Keywords: follicle development; premature ovarian insufficiency; signal transduction; apoptosis autophagy; aging; reproductive biotechnology; organ-on-chip
(This special issue belongs to the Section Molecular Biology)
Advances and Perspectives in Molecular Tumor Therapy
edited by
submission deadline 20 Sep 2024 | Viewed by 358 | Submission Open
Keywords: tumorigenesis; immunotherapy; targeted therapy; tumor microenvironment; anti-cancer drugs
(This special issue belongs to the Section Molecular Oncology)
Toxic Effects of Cancer Treatments: Update on Targeted Molecular Approaches and Signalling Pathways
edited by and Éric Morel
submission deadline 20 Sep 2024 | Viewed by 357 | Submission Open
Keywords: radiotherapy; cancer treatment; chemotherapy; toxicities; hormone therapy; molecular signaling pathway
(This special issue belongs to the Section Molecular Toxicology)
Molecular and Epigenetic Regulation in Seed Development
edited by and Qingyun Bu
submission deadline 20 Sep 2024 | Viewed by 351 | Submission Open
Keywords: seed development; molecular mechanism; epigenetic modification; gene function; genetic improvement  
(This special issue belongs to the Section Molecular Plant Sciences)
Rejuvenation of Cells in Human Health and Diseases
edited by Stina Simonsson
submission deadline 20 Sep 2024 | Viewed by 348 | Submission Open
Keywords: cell rejuvenation; rejuvenation pathways; stem cell; osteoarthritis; cartilage regeneration; joint repair
(This special issue belongs to the Section Molecular Biology)
Molecular Materials for Functional Textile Coatings
edited by
submission deadline 20 Sep 2024 | Viewed by 343 | Submission Open
Keywords: smart textiles; electronic textiles; medical textiles; protective textiles; nano-finishing
(This special issue belongs to the Section Materials Science)
IQSEC2 Mediated Diseases: From Mechanisms to Treatment
edited by
submission deadline 20 Sep 2024 | Viewed by 338 | Submission Open
Keywords: IQSEC2; epilepsy; autism; intellectual disability; animal model; gene therapy; pharmacogenomics
(This special issue belongs to the Section Molecular Genetics and Genomics)
Advanced Research in Mitochondrial Genetics
edited by
submission deadline 20 Sep 2024 | Viewed by 324 | Submission Open
Keywords: mitochondrial DNA sequencing; whole-exome sequencing; whole-genome sequencing; single-cell-sequencing; formalin-fixed-paraffin-embedded tissues; spatial-whole-transcriptomics; mitochondrial diseases
(This special issue belongs to the Section Molecular Biology)
New Insights into Mitochondria in Health and Diseases submission deadline 20 Sep 2024 | Viewed by 321 | Submission Open
Keywords: mitochondrial bioenergetics; reactive oxygen species; apoptosis; aging; immune function; mtDNA mutations; mitochondrial dysfunction; mitochondria-targeted therapies
(This special issue belongs to the Section Biochemistry)
The Role of Phenolic Compounds and Metabolites in Human Health submission deadline 20 Sep 2024 | Viewed by 321 | Submission Open
Keywords: phenolic compounds; phenolic metabolites; cardiovascular diseases; cancer; diabetes; colon metabolism; microbiota; cell culture; clinical studies
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Skeletal Muscle Metabolism—Effects of Diet, Exercise and Pharmacotherapies
edited by
submission deadline 20 Sep 2024 | Viewed by 297 | Submission Open
Keywords: energy metabolism; metabolic signaling pathways; metabolic homeostasis; metabolic disorders; muscle mass; muscle metabolites; diet; exercise; pharmacotherapies
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Insight on Nanoparticle Toxicity
edited by Fátima Brandão
submission deadline 20 Sep 2024 | Viewed by 292 | Submission Open
Keywords: nanoparticles; toxicity; mechanisms; safe-by-design; molecular pathways; 3R principles
(This special issue belongs to the Section Molecular Nanoscience)
Recent Advances and Insights in Treatment of Urinary Tract Diseases
edited by Cheng-Yu Long
submission deadline 20 Sep 2024 | Viewed by 279 | Submission Open
Keywords: pathophysiology of UTD; UTD treatment modality; new therapeutic approaches and its basic mechanism; medication management of UTD; estrogen deprivation and UTD; bench work of lower urinary tract dysfunction; new advances in treatment of UTD
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Exploring Abiotic Stress in Plants: Mechanisms, Adaptations, and Mitigation Strategies
edited by
submission deadline 20 Sep 2024 | Viewed by 270 | Submission Open
Keywords: abiotic stress; plant physiology; stress tolerance; crop resilience; molecular mechanisms; biotechnological interventions
(This special issue belongs to the Section Molecular Plant Sciences)
New Insights into Lipids and Immune Responses
edited by Adam Shahine
submission deadline 20 Sep 2024 | Viewed by 267 | Submission Open
Keywords: immune system; lipids; antigen presentation; T-cell responses; bacterial infection; autoimmunity; inflammation
(This special issue belongs to the Section Molecular Immunology)
The Role of Genome in Cancer Therapy
edited by Yoav Smith and Hovav Nechushtan
submission deadline 20 Sep 2024 | Viewed by 251 | Submission Open
Keywords: genome analysis; molecular therapy; drug resistance; cancer genetic
(This special issue belongs to the Section Molecular Genetics and Genomics)
Coumarins as Effective Therapeutic Agents: Mechanism of Action and Diverse Activity
edited by
submission deadline 20 Sep 2024 | Viewed by 233 | Submission Open
Keywords: furanocoumarins; pyranocoumarins; simple coumarins; anti-inflammatory properties; cytotoxic activity; antitumor activity; antimicrobial acitivity; bioactivity of compounds; anxiolytic activity; neuroprotective properties; bioactive metabolites; medicinal plants
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cardiovascular Diseases: From Molecular Mechanisms to Innovative Therapeutics submission deadline 20 Sep 2024 | Viewed by 230 | Submission Open
Keywords: cardiovascular diseases; diabetes; hypertension; obesity; venous thromboembolism; pulmonary embolism; deep vein thrombosis; bleeding; coagulation; clotting factor
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Lipopolysaccharide in the Health and Disease
edited by and Hiroyuki Inagawa
submission deadline 20 Sep 2024 | Viewed by 228 | Submission Open
Keywords: usefulness of LPS; oral and/or dermal administration of LPS; lifestyle disease; cognitive dysfunction; allergy; autoimmune disorder; wound healing; cancer
(This special issue belongs to the Section Biochemistry)
Lipid Metabolism and Biomarkers in Neural and Cardiometabolic Health
edited by
submission deadline 20 Sep 2024 | Viewed by 227 | Submission Open
Keywords: lipid species; cardiovascular health; neural health; inflammation; cardiac biomarkers; neural biomarkers
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Cellular and Molecular Mechanisms of Autoimmune Disorders
edited by
submission deadline 20 Sep 2024 | Viewed by 217 | Submission Open
Keywords: autoimmune diseases; self-tolerance; immune cells; autoantibodies; autoantigens; pathomechanisms
(This special issue belongs to the Section Molecular Immunology)
Prebiotics and Probiotics: Healthy Biotools for Molecular Integrative and Modulation Approaches—3rd Edition submission deadline 20 Sep 2024 | Viewed by 203 | Submission Open
Keywords: prebiotics; probiotics; molecular microbiology; immunology; microbiome
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Plant Metabolites with Pro-cognitive and Neuroprotective Effects submission deadline 20 Sep 2024 | Viewed by 198 | Submission Open
Keywords: neuroprotection; cognitive impairment; plant secondary metabolites; Alzheimer’ s disease; memory deficits; ADME
(This special issue belongs to the Section Bioactives and Nutraceuticals)
The Significance of MicroRNAs in Cancer Development
edited by Shipra Malik
submission deadline 20 Sep 2024 | Viewed by 172 | Submission Open
Keywords: oncomiRs; tumor suppressor miRs; cancer progression; metastasis; cancer resistance; cancer therapy; biomarkers; miRNA mimics; antisense therapy; gene therapy
(This special issue belongs to the Section Molecular Biology)
Natural Products in Cancer Treatments
edited by Deborah A. Lannigan
submission deadline 20 Sep 2024 | Viewed by 156 | Submission Open
Keywords: natural products; bioactive; chemotherapy; anti-cancer; targeted therapy
(This special issue belongs to the Section Molecular Oncology)
Advances in Classic and Psychedelic Pharma for Psychiatric Diseases
edited by Gal Yadid
submission deadline 20 Sep 2024 | Viewed by 140 | Submission Open
Keywords: anti-psychiatric drug/treatment; psychedelic; molecular mechanism; neurotransmission; plasticity; neurogenesis; response variability  
(This special issue belongs to the Section Molecular Pharmacology)
The Relevance of Lipid Metabolism in Viral Hepatitis and Hepatocellular Carcinoma
edited by Georgios Grammatikos
submission deadline 21 Sep 2024 | Viewed by 228 | Submission Open
Keywords: sphingolipid; ceramide; HCC; viral hepatitis; sphingomyelinase; exosomes; immune therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Role of Immune Cells in Non-infectious Inflammatory Diseases and Cancers
edited by
submission deadline 25 Sep 2024 | 10 articles | Viewed by 13775 | Submission Open
Keywords: cytokines; immunity cells; atherosclerosis; inflammation; immunity
(This special issue belongs to the Section Molecular Immunology)
Advances in Plant–Pathogen Interactions: 3rd Edition
edited by
submission deadline 25 Sep 2024 | 8 articles | Viewed by 9985 | Submission Open
Keywords: host; effection; pathogenicity; pathogen; plant immunity; interactions
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Pathogenesis and Treatment of Pregnancy Complications
edited by Radzisław Mierzyński and
submission deadline 25 Sep 2024 | 7 articles | Viewed by 7815 | Submission Open
Keywords: preterm delivery; intraamniotic infection; preeclampsia; hypertension; metabolic syndrome; maternal health; prematurity
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research on Type 1 Diabetes and Its Complications submission deadline 25 Sep 2024 | 8 articles | Viewed by 7801 | Submission Open
Keywords: type 1 diabetes mellitus; diabetic microangiopathy; diabetic macroangiopathy; continuous glucose monitoring; experimental diabetic models; biomarkers; endothelium dysfunction; diabetes-related diseases; comorbidities; pregnancy; pathophysiology; metabolic syndrome; treatment; precision medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Multifactorial and Multicomponent Influence Assessment on the Toxic Effects Development
edited by Ilzira A. Minigalieva
submission deadline 25 Sep 2024 | 2 articles | Viewed by 4337 | Submission Open
Keywords: toxicology of mixtures; combined toxicity; experimental studies
(This special issue belongs to the Section Molecular Toxicology)
Anti-obesity Drug Discovery
edited by Dana Mullerova
submission deadline 25 Sep 2024 | 2 articles | Viewed by 3103 | Submission Open
Keywords: gut-derived hormones and gut brain axis (nutrient stimulated hormone based therapy); other gut peptide-related approaches; gut microbiome; mitochondrial uncouplers (DNPME/CRMP); CNS secreted neuropeptides and antagonists; adipose tissue hormones and adipokines
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Studies on Plant and Plant In Vitro Systems Secondary Metabolism
edited by
submission deadline 25 Sep 2024 | 2 articles | Viewed by 3016 | Submission Open
Keywords: plants; plant in vitro systems; secondary metabolism; sustainable production; elicitation; metabolic engineering; CRISPR/Cas; molecular targets  
(This special issue belongs to the Section Molecular Plant Sciences)
Cellular and Molecular Progression of Cardiovascular Diseases submission deadline 25 Sep 2024 | 2 articles | Viewed by 2711 | Submission Open
Keywords: cardiovascular diseases; multi-omics data; biomarkers; molecular level; pathophysiology
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research and Treatment in Multiple Sclerosis
edited by Nada Starčević Čizmarević and
submission deadline 25 Sep 2024 | 2 articles | Viewed by 1759 | Submission Open
Keywords: multiple sclerosis; neuroinflammation; neurodegeneration; genetics; molecular research; biomarkers; neuroimaging; therapy
(This special issue belongs to the Section Molecular Biology)
Plant Chloroplasts and Mitochondria: Key Organelles for Sustainable Agriculture
edited by
submission deadline 25 Sep 2024 | 2 articles | Viewed by 1449 | Submission Open
Keywords: ‘ omics’ ; photosynthesis; energy production; crops; climate change; sustainable agriculture; stress response; inter-organelle crosstalk; signaling networks; genetic engineering
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Mechanisms of Oral and Gastrointestinal Bacterial Interaction
edited by Denisse Bravo
submission deadline 25 Sep 2024 | 1 articles | Viewed by 1051 | Submission Open
Keywords: oral and gastrointestinal microbiota; bacterial interaction; pathogenic mechanisms; immune responses; biofilm formation; bacterial adhesion; microbial metabolites
(This special issue belongs to the Section Molecular Microbiology)
Molecular Progression of Genetics in Breeding of Farm Animals
edited by
submission deadline 25 Sep 2024 | 1 articles | Viewed by 953 | Submission Open
Keywords: farm animal; livestock; genome sequencing
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Mechanisms and Therapies of Brain Tumors
edited by Oana Alexandru
submission deadline 25 Sep 2024 | 1 articles | Viewed by 913 | Submission Open
Keywords: brain tumors; molecular mechanisms; signal transduction; cell proliferation; apoptosis; targeted therapies; chemotherapy; radiotherapy
(This special issue belongs to the Section Molecular Oncology)
Toxicology and Pharmacology of Natural Products
edited by , Cheng Zhang and Sha Li
submission deadline 25 Sep 2024 | Viewed by 825 | Submission Open
Keywords: pharmacology; toxicology; natural products; Chinese medicine; drug discovery; safety assessment; ethnopharmacology; analytical techniques; regulatory frameworks
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Advances in Gestational Diabetes Mellitus
edited by Natasha Singh
submission deadline 25 Sep 2024 | Viewed by 281 | Submission Open
Keywords: metabolome; placental insulin signaling; DNA methylation; mitochondrial oxidation; MTOR; amino acids lipidomics; proteomics; gluconeogenesis; GDM
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Endothelial Dysfunction and Its Related Cardiometabolic Disorders: From Mechanisms to Targeted Therapies
edited by
submission deadline 25 Sep 2024 | Viewed by 249 | Submission Open
Keywords: endothelial dysfunction; endothelial activation; endothelial nitric oxide synthase; cardiometabolic disease; vascular inflammation; chemokines; adipocytokines; atherosclerosis; diabetes; biomarkers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research of Nanocomposites: Design, Properties and Application
edited by
submission deadline 25 Sep 2024 | Viewed by 202 | Submission Open
Keywords: interfacial thermal resistance; polymer-based nanocomposites; polymers; thermal conductivity; thermal-interface materials
(This special issue belongs to the Section Materials Science)
Biomolecular Mechanisms of Natural Products: Cannabis and Alkaloid-Producing Plants
edited by Craig M. Schluttenhofer
submission deadline 25 Sep 2024 | Viewed by 153 | Submission Open
Keywords: alkaloids; biosynthesis; cannabis; cannabinoids; hemp; natural products  
(This special issue belongs to the Section Biochemistry)
Macrophage Polarization and Human Inflammatory Diseases submission deadline 25 Sep 2024 | Viewed by 151 | Submission Open
Keywords: macrophage polarization; inflammation; metabolic immunomodulation; epigenetics; in vitro models; in vivo models; diagnostics; therapeutics; infectious disease; metabolic disease
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Developments and Prospects in Thyroid Cancer
edited by Marilena Celano
submission deadline 25 Sep 2024 | Viewed by 129 | Submission Open
Keywords: genetic; epigenetic; molecular mechanisms; microRNA; thyroid cancer
(This special issue belongs to the Section Molecular Oncology)
Molecular Metabolism in the Tumor Microenvironment
edited by Valentina Comunanza
submission deadline 26 Sep 2024 | Viewed by 277 | Submission Open
Keywords: cell metabolism; tumor microenvironment; metabolic reprogramming; cancer therapy; endothelial cells; fibroblasts; adaptive and innate immunity
(This special issue belongs to the Section Biochemistry)
Plant Nitrogen Metabolism: Current Status and Future Directions
edited by
submission deadline 27 Sep 2024 | Viewed by 559 | Submission Open
Keywords: nitrate; ammonium; amides; ureides; nitrogen fixation; reactive nitrogen species; nitrogen signalling; nitrogen molecules in response to stress; nitrogen molecules in mobilization situations; sustainable agriculture
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Mechanisms and Treatment of Migraine
edited by Noboru Imai
submission deadline 27 Sep 2024 | Viewed by 252 | Submission Open
Keywords: migraine; nitric oxide synthase (NOS); neuropeptides; calcitonin gene-related peptide (CGRP); pituitary adenylate cyclase activating polypeptide (PACAP); molecular pathways; therapeutic targets; neurovascular condition
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
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