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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Diagnosis and Latest Treatment for Gastric Cancer

edited by

Petra Hudler

submission deadline 20 Nov 2025 | 2 articles | Viewed by 4901 | Submission Open

Keywords: gastric cancer; biomarkers; genetics; epigenetics; immunotherapy; molecular diagnostics; personalized medicine; predisposition; risk factors

(This special issue belongs to the Section Molecular Oncology)

Molecular Research on Pathogenesis and Treatment of Pregnancy Complications

edited by

Melissa Wilson

submission deadline 20 Nov 2025 | 3 articles | Viewed by 4883 | Submission Open

Keywords: hypertensive disorders of pregnancy; preeclampsia; molecular biology; biomarker; prevention; therapeutics; placenta

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research and Potential Effects of Medicinal Plants

edited by

Guan-Jhong Huang

submission deadline 20 Nov 2025 | 4 articles | Viewed by 4853 | Submission Open

Keywords: medicinal plants; natural products; disease treatment; drug screening; bioassays

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Advances in Burn and Wound Healing

edited by

Alisha R. Oropallo

submission deadline 20 Nov 2025 | 4 articles | Viewed by 4754 | Submission Open

Keywords: burn; wound; molecular mechanisms; cell signaling; growth factors; cytokines; extracellular matrix; angiogenesis; healing

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances and Perspectives of Lung Disease: 2nd Edition

edited by

Longshuang Huang

submission deadline 20 Nov 2025 | 3 articles | Viewed by 4527 | Submission Open

Keywords: lung disease; inflammation; regeneration; infection; drug discovery

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Editorial Board Members’ Collection Series: “Protein Biophysics”

edited by

Vladimir N. Uversky

and

Assaf Friedler

submission deadline 20 Nov 2025 | 2 articles | Viewed by 4454 | Submission Open

Keywords: protein structure and prediction; protein biophysics; protein dynamics; peptide and protein aggregation; protein misfolding; protein folding; protein stability; protein function; posttranslational modifications; intrinsically disordered proteins; protein– ligand interactions; protein– protein interactions; protein– nucleic acid interactions; membrane proteins; liquid– liquid phase separation

(This special issue belongs to the Section Molecular Biophysics)

The Effects of Dietary Supplements, Functional Foods and Nutraceuticals in the Immune System

edited by

Kaleta Beata

submission deadline 20 Nov 2025 | 1 articles | Viewed by 4422 | Submission Open

Keywords: dietary supplements; functional foods; immune system; immunomodulation; nutraceuticals

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Inflammatory Biomarkers in Ischemic Stroke

edited by Hanna Pawluk and

Renata Kołodziejska

submission deadline 20 Nov 2025 | 3 articles | Viewed by 4302 | Submission Open

Keywords: stroke; brain tissue damage; ischemic stroke; inflammatory markers; immune response

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pain: From Molecular Basis to Therapy

edited by Samuel J. Lin

submission deadline 20 Nov 2025 | 2 articles | Viewed by 4257 | Submission Open

Keywords: pain mechanisms; molecular signaling; neurotransmitters; ion channels; genetic predisposition; epigenetic regulation; immune– neuron interaction; pharmacological therapy; gene therapy; neuromodulation; regenerative medicine

(This special issue belongs to the Section Molecular Neurobiology)

Rheumatoid Arthritis: From Molecular Basis to Therapies

edited by

Gabriella Sármay

submission deadline 20 Nov 2025 | 3 articles | Viewed by 4220 | Submission Open

Keywords: rheumatoid arthritis; autoimmune; intracellular signaling pathways; targeted therapy; inflammation; immunometabolic reprogramming; CD40; CD40 ligand; GM-CSF; PD-1; inhibitors

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Targeted Therapies and Molecular Methods in Cancer, 3rd Edition

edited by

Julita Kulbacka

submission deadline 20 Nov 2025 | 3 articles | Viewed by 4205 | Submission Open

Keywords: immunotherapy; radiotherapy; methods using facilitated drug delivery such as electroporation; sonoporation; and magnetic fields; nanotechnology and nanocarriers; gene electrotherapy; intelligent predicting methods with AI

(This special issue belongs to the Section Molecular Oncology)

Genetic Testing in Molecular Pathology and Diagnosis

edited by

Marco Fabiani

submission deadline 20 Nov 2025 | 3 articles | Viewed by 4133 | Submission Open

Keywords: genetic testing; molecular pathology; personalized medicine; genetic diagnostics; disease mechanisms; novel genetic tests; clinical integration; patient management

(This special issue belongs to the Section Molecular Biology)

Extracellular Vesicles (EVs) in Cancer Progression and Metastasis: Molecular Insights and Clinical Outlook

edited by Alfredo Cappariello

submission deadline 20 Nov 2025 | 2 articles | Viewed by 4097 | Submission Open

Keywords: mammalian extracellular vesicles; plant-derived extracellular vesicles; bacterial-derived extracellular vesicles; cancer progression; cell migration and invasion; tumor microenvironment; epithelial-to-mesenchymal transition (EMT); drug delivery; diagnostics; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Tissue Engineering Related Biomaterials: Progress and Challenges

edited by

Mihaela Violeta Ghica

Lacramioara Popa

and Cristina Elena Dinu-Pirvu

submission deadline 20 Nov 2025 | 2 articles | Viewed by 4042 | Submission Open

Keywords: biomaterials; tissue engineering; scaffold materials; regenerative medicine; cell– material interactions; tissue regeneration; bioactive materials; nanotechnology in tissue engineering; electrospinning; 3D printing; biodegradable materials; growth factors

(This special issue belongs to the Section Materials Science)

Advancing Cancer Research: Molecular Insights, Diagnostic Innovations and Therapeutic Targets

edited by Jue Wang

submission deadline 20 Nov 2025 | 2 articles | Viewed by 4026 | Submission Open

Keywords: cancer; carcinogenesis; molecular pathology; signaling transduction; diagnosis; treatment; prognosis; pathogenesis; precision oncology; biomarker discovery; genomic profiling

(This special issue belongs to the Section Molecular Oncology)

Molecular Perspectives in the Diagnosis, Prevention, Treatment, and Vaccination Against Parasitic Diseases

edited by

Bartłomiej Tomasz Ferra

and Anna Lass

submission deadline 20 Nov 2025 | 3 articles | Viewed by 3998 | Submission Open

Keywords: parasitoses; vaccines; diagnostic; epidemiology; prevention; antibodies; cytokines; immune system; treatment; native antigen; recombinant protein; chimeric recombinant protein; multiepitope recombinant protein; pharmaceutical analogues; PCR; molecular techniques

(This special issue belongs to the Section Molecular Microbiology)

TGF-β Signaling in Immunity, Inflammation, Fibrosis and Cancer

edited by

Isabel Fabregat

and

Gianluigi Giannelli

submission deadline 20 Nov 2025 | 1 articles | Viewed by 3991 | Submission Open

Keywords: TGF-beta; fibrosis; inflammation; cancer; immune cells; fibroblasts; EMT; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Advanced Research on Cholangiocarcinoma: From Bench to Bedside

edited by

Masaru Katoh

, Simona Tavolari and

Giovanni Brandi

submission deadline 20 Nov 2025 | 3 articles | Viewed by 3979 | Submission Open

Keywords: risk factors; next-generation sequencing; actionable targets; FGFR2; BAP1; IDH1; tissular/circulating biomarkers; cancer resistance; immune microenvironment; in vitro and in vivo models; clinical trials

(This special issue belongs to the Section Molecular Oncology)

Therapeutic Potential of Antioxidants in the Prevention of Human Diseases, 2nd Edition

edited by

Kota V. Ramana

submission deadline 20 Nov 2025 | 2 articles | Viewed by 3931 | Submission Open

Keywords: antioxidants; vitamins; inflammation; cancer; neurological complications; diabetes; flavonoids; natural compounds; cancer; infections; COVID-19

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Male Reproductive Physiology, Pathophysiology, and Contraception

edited by Gustavo G. Blanco

submission deadline 20 Nov 2025 | 2 articles | Viewed by 3840 | Submission Open

Keywords: spermatogenesis; spermiogenesis; testis; epididymis; sperm function; sperm motility; sperm capacitation; acrosome reaction; male reproduction; male fertility; male infertility; male contraception

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Sjögren’s Syndrome: From Pathogenesis to Therapy

edited by Alexandru Emil Caraba

submission deadline 20 Nov 2025 | 2 articles | Viewed by 3732 | Submission Open

Keywords: Sjö gren's syndrome; salivary glands; lacrimal glands; T and B cells; macrophage; dendritic cells; salivary gland epithelial cells; inflammatory mediators (cytokines; chemokines; antibodies); intracellular signaling pathways (IFN; TLR; BAFF/BAFF-R; PI3K/Akt/mTOR); atherosclerosis; lymphoma; novel therapeutic strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Insights into Bone Tissue: Pathologies and Therapeutic Strategies

edited by

Francesca Salamanna

submission deadline 20 Nov 2025 | 1 articles | Viewed by 3692 | Submission Open

Keywords: bone tissue; pathologies; regenerative medicine; biomechanics; diagnostics; therapeutic strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights into Plant–Environment Interactions

edited by

Magdalena Pawełkowicz

submission deadline 20 Nov 2025 | 1 articles | Viewed by 3669 | Submission Open

Keywords: vascular biology; floral development; sex expression; fruit development; grafting; source– sink interactions; genetic resources; stress tolerance; molecular breeding; gene regulation; resistance to biotic and abiotic stresses

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanism in Multiple Sclerosis and Related Disorders: 3rd Edition

edited by

Hans-Peter Hartung

and Kazuo Fujihara

submission deadline 20 Nov 2025 | 3 articles | Viewed by 3598 | Submission Open

Keywords: neurodegeneration; multiple sclerosis; NMOSD; MOGAD; disease-modifying treatments

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Colorectal Cancer: From Pathophysiology to Novel Therapies

edited by

Fabio Gelsomino

submission deadline 20 Nov 2025 | 2 articles | Viewed by 3588 | Submission Open

Keywords: colorectal cancer; immunotherapy; targeted therapy; biomarkers; multidisciplinary management; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biomarkers in Precision Medicine

edited by

Zhidong Zhou

submission deadline 20 Nov 2025 | 1 articles | Viewed by 3549 | Submission Open

Keywords: biomarkers; precision medicine; novel techniques; artificial intelligence

(This special issue belongs to the Section Molecular Biology)

Mechanisms and Implications of Traumatic Brain Injury and Neuroinflammation

edited by

Kwang Choi

submission deadline 20 Nov 2025 | 3 articles | Viewed by 3451 | Submission Open

Keywords: traumatic brain injury; head trauma; neuroinflammation; secondary injury; microglia

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Design of Artificial Receptors Using Virtual Approaches

edited by Houjin Zhang

submission deadline 20 Nov 2025 | 2 articles | Viewed by 3422 | Submission Open

Keywords: artificial receptors; protein design; computational biology; drug targeting; biosensors; tissue engineering; synthetic biology

(This special issue belongs to the Section Molecular Biophysics)

New Insights in Artificial Intelligence for Drug Design and Target Discovery

edited by

Yanjing Wang

submission deadline 20 Nov 2025 | 2 articles | Viewed by 3406 | Submission Open

Keywords: pre-trained language models; generative models; drug prediction; binding site prediction; peptides; multi-omics; deep learning; QSAR modeling; molecular dynamics (MD) simulations

(This special issue belongs to the Section Molecular Pharmacology)

Advanced Research in Immunotoxicity and Oxidative Stress

edited by

Soo-Jin Choi

submission deadline 20 Nov 2025 | 1 articles | Viewed by 3345 | Submission Open

Keywords: toxicity; macrophage activation; pro-inflammation; anti-inflammation; oxidative stress; foods; food additives; nanomaterials; toxicants; natural compounds

(This special issue belongs to the Section Molecular Toxicology)

Recent Advances in Nanoparticles in Molecular Biology: Second Edition

edited by

Maciej Monedeiro-Milanowski

submission deadline 20 Nov 2025 | 1 articles | Viewed by 3299 | Submission Open

Keywords: nanoparticles; nanomedicine; biomolecules; nanoparticle– cell interactions; organic– inorganic hybrid; cytotoxic potential

(This special issue belongs to the Section Molecular Nanoscience)

Phytohormone Signaling and Crosstalk in Regulation of Plant Growth and Environmental Stress Responses: 2nd Edition

edited by

Lam-Son Phan Tran

and Mohammad G. Mostofa

submission deadline 20 Nov 2025 | 2 articles | Viewed by 3297 | Submission Open

Keywords: plant hormones; hormonal crosstalk; signal transduction; stress signaling; root system architecture; shoot branching; leaf development; phytohormone-responsive factors; transcriptional regulators; gene expression; plant physiology; senescence; plant plasticity; regulatory mechanisms; hormone homeostasis; stress adaptation/acclimatization

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insights into Placental Pathology

edited by

Mary Wallingford

and Ana Correia-Branco

submission deadline 20 Nov 2025 | 3 articles | Viewed by 3275 | Submission Open

Keywords: placenta; trophoblast; implantation; obstetrics; pre-eclampsia; placentation; maternal– fetal interface; pregnancy health; placenta diagnostics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Amyloid in Neurological Diseases

edited by Silvia Purro

submission deadline 20 Nov 2025 | 2 articles | Viewed by 3252 | Submission Open

Keywords: amyloid-beta (Aβ ); tau protein; TDP43; synuclein; huntingtin; prion-like mechanisms; amyloid structures; genetic factors; cell-to-cell transmission; pathogenesis mechanisms; protein aggregation; Biomarkers; CNS amyloid clearance and degradation

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Molecular Mechanisms of Kidney Disease: Integrating Renal Tumorigenesis

edited by

Michele Marchioni

and

Luigi Schips

submission deadline 20 Nov 2025 | 1 articles | Viewed by 3242 | Submission Open

Keywords: molecular pathogenesis; renal cell carcinoma; genomic profiling; targeted therapy; immunotherapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biological Hallmarks and Therapeutic Strategies in Cancer

edited by Ramesh Kumar

submission deadline 20 Nov 2025 | 2 articles | Viewed by 3198 | Submission Open

Keywords: hallmarks of cancer; cancer progression; chemotherapy; tumorigenesis; oncogenic signaling

(This special issue belongs to the Section Molecular Oncology)

Endothelial-to-Mesenchymal Transition: A Key Driver of Tumor Progression and Therapeutic Resistance

edited by

Gabriella Doronzo

submission deadline 20 Nov 2025 | 1 articles | Viewed by 3176 | Submission Open

Keywords: Endothelial-to-Mesenchymal Transition; wound healing and fibrosis; tumor progression; abnormal blood vessel formation; cancer therapy

(This special issue belongs to the Section Molecular Biology)

Computational Approaches for Protein Design

edited by Livija Jakaite and

Mahesh Narayan

submission deadline 20 Nov 2025 | 3 articles | Viewed by 3160 | Submission Open

Keywords: computational protein design; molecular structure prediction; deep learning; protein structure and function prediction

(This special issue belongs to the Section Molecular Biophysics)

MicroRNA (miRNA) Technology in Cancer

edited by

Duncan Ayers

submission deadline 20 Nov 2025 | 2 articles | Viewed by 3129 | Submission Open

Keywords: miRNA; microRNA; cancer; oncology; drug delivery; technology; non-coding RNA

(This special issue belongs to the Section Molecular Oncology)

Molecular Advances in Semiconductor Materials

edited by Tarek Hidouri

submission deadline 20 Nov 2025 | 1 articles | Viewed by 3069 | Submission Open

Keywords: optoelectronics; hybrid materials; power devices; III– V materials; advanced characterization; modeling; molecular advances; semiconductors; biophysics

(This special issue belongs to the Section Materials Science)

Anti-Inflammatory Strategies and Cell Models for Alzheimer’s Disease

edited by Sophia Lavrentiadou

submission deadline 20 Nov 2025 | 1 articles | Viewed by 3030 | Submission Open

Keywords: Alzheimer’ s disease; neuroinflammation; anti-inflammatory strategies; cell models

(This special issue belongs to the Section Molecular Neurobiology)

Computational Design and Therapeutic Applications of Peptide-Based Drugs

edited by

Shayon Bhattacharya

submission deadline 20 Nov 2025 | 1 articles | Viewed by 3002 | Submission Open

Keywords: peptide drug design; in silico drug discovery; peptide– protein interactions; therapeutic peptides

(This special issue belongs to the Section Molecular Biology)

Regulatory Network of Bone Metabolism

edited by

Kazunori Hamamura

submission deadline 20 Nov 2025 | 2 articles | Viewed by 2993 | Submission Open

Keywords: osteoblasts; osteoclasts; osteocytes; mesenchymal stem cells; bone metabolism; bone formation; bone resorption

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

New Advances in Germ Cell Research

edited by

Sheng-Hsiang Li

submission deadline 20 Nov 2025 | 2 articles | Viewed by 2966 | Submission Open

Keywords: spermatogenesis; sperm capacitation; oogenesis; oocyte maturation; cumulus cells; fertilization; gene expression; biomarkers; exosomes; infertility

(This special issue belongs to the Section Molecular Biology)

Peptides and Peptidomimetics for Targeting Protein-Protein Interactions

edited by

Giacomo Rossino

and

Pasquale Linciano

submission deadline 20 Nov 2025 | 1 articles | Viewed by 2963 | Submission Open

Keywords: protein– protein interactions; peptide– protein interactions; interactome; proteomics; peptides; modified peptides; peptidomimetics; molecular glues; drug discovery; medicinal chemistry; rule of five; biophysical assays; molecular modelling; cancer; neurodegenerative diseases; orphan diseases; antimicrobial resistance; PROTAC

(This special issue belongs to the Section Biochemistry)

Multi-Omics Analysis and Application of Plant Natural Products (2nd Edition)

edited by

Qiang Zhang

submission deadline 20 Nov 2025 | 1 articles | Viewed by 2939 | Submission Open

Keywords: omics; plant components; bioactivity; signaling; pathway; target; mechanism

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Whole-Cell System and Synthetic Biology, 2nd Edition

edited by

Jingjing Tian

submission deadline 20 Nov 2025 | 2 articles | Viewed by 2936 | Submission Open

Keywords: synthesis biology; molecular biology; functional nucleic acids; biosensor; CRISPR-Cas; directed evolution; whole-cell system

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research in Animal Reproduction

edited by

Zhongliang Jiang

submission deadline 20 Nov 2025 | 3 articles | Viewed by 2925 | Submission Open

Keywords: spermatogenesis; follicular atresia; oocyte maturation; granulosa cells; hormone regulation; autophagy; apoptosis; miRNA; signaling regulation

(This special issue belongs to the Section Molecular Biology)

Protein Dynamics, Binding and Allostery

edited by

Beatriz Ibarra-Molero

Raquel Godoy-Ruiz

and

Encarnación Medina Carmona

submission deadline 20 Nov 2025 | 1 articles | Viewed by 2916 | Submission Open

Keywords: proteins dynamics; enzyme catalysis; conformational changes; allosteric regulation; signal transduction; neurodegenerative disorders; cancer; computational methods; therapeutic interventions

(This special issue belongs to the Section Biochemistry)

Effects of Ionizing Radiation in Cancer Radiotherapy: 2nd Edition

edited by

François Chevalier

submission deadline 20 Nov 2025 | 2 articles | Viewed by 2916 | Submission Open

Keywords: non-targeted effects; radiation-induced bystander effect; abscopal effect; genomic instability; low dose effects; radioprotection; circulating biomarkers; oxidative stress

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 101-150 on page 3 of 67.

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