Retinal Diseases: From Molecular Pathology to Therapies—2nd Edition

Dear Colleagues,

The identification of mechanisms underlying the pathophysiology and therapies of retinal diseases continues to be an area of significant research activity, attracting scientists from a diverse range of fields, including neuroscience, pharmacology, and medicinal chemistry, among several others. With the ultimate goal of generating intervention strategies that slow or even reverse the structural and functional degeneration of the retina and that attenuate or eliminate subsequent vision loss, with input from numerous fields, such as neurology, ophthalmology, genetics, and neuroscience, effective therapies for many retinal diseases are lacking and critically needed.

Research efforts towards preventing, treating, or curing retinal diseases are characteristic for how clinical practice as well as basic and translational research inform each other and how such interactions can result in novel therapeutic strategies of high clinical relevance. Recent methodological advances in synthetic and medicinal chemistry, mass spectrometry, proteomics, drug target discovery, and drug development have generated significant developments in this field. Therefore, this Special Issue invites manuscript submissions, namely research and review papers, targeting the gamut of methodological and scientific innovation in this field. This Special Issue specifically calls for papers focused on the discovery and mechanistic characterization of novel drug targets, signaling pathways, and mechanisms of action, as they are relevant for retinal diseases. These contributions can be general and broad in their basic science, and translational research can focus more on specific research models related to the structural and functional degeneration of the retina and related complications.

Prof. Dr. Peter Koulen
Guest Editor

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