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Most Cited & Viewed - Int. J. Mol. Sci.

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Citations	Article
1186	Review: Pretreatment of Lignocellulosic Wastes to Improve Ethanol and Biogas Production: A Review by Mohammad J. Taherzadeh and Keikhosro Karimi
579	Review: An Updated Review of Tyrosinase Inhibitors by Te-Sheng Chang
398	Review: Impact of Dietary Polyphenols on Carbohydrate Metabolism by Kati Hanhineva, Riitta Törrönen, Isabel Bondia-Pons, Jenna Pekkinen, Marjukka Kolehmainen, Hannu Mykkänen and Kaisa Poutanen
394	Review: Dietary Polyphenols and Their Biological Significance by Xiuzhen Han, Tao Shen and Hongxiang Lou
388	Review: Obesity and Its Metabolic Complications: The Role of Adipokines and the Relationship between Obesity, Inflammation, Insulin Resistance, Dyslipidemia and Nonalcoholic Fatty Liver Disease by Un Ju Jung and Myung-Sook Choi
382	Review: Biological Activities of Polyphenols from Grapes by En-Qin Xia, Gui-Fang Deng, Ya-Jun Guo and Hua-Bin Li
344	Review: Inflammation, Oxidative Stress, and Obesity by Alba Fernández-Sánchez, Eduardo Madrigal-Santillán, Mirandeli Bautista, Jaime Esquivel-Soto, Ángel Morales-González, Cesar Esquivel-Chirino, Irene Durante-Montiel, Graciela Sánchez-Rivera, Carmen Valadez-Vega and José A. Morales-González
334	Review: Microfluidic Mixing: A Review by Chia-Yen Lee, Chin-Lung Chang, Yao-Nan Wang and Lung-Ming Fu
319	Review: Biodegradability of Plastics by Yutaka Tokiwa, Buenaventurada P. Calabia, Charles U. Ugwu and Seiichi Aiba
317	Review: Green Extraction of Natural Products: Concept and Principles by Farid Chemat, Maryline Abert Vian and Giancarlo Cravotto

Citations	Article
15	Review: Medicinal Plants Used in the Treatment of Human Immunodeficiency Virus by Bahare Salehi, Nanjangud V. Anil Kumar, Bilge Şener, Mehdi Sharifi-Rad, Mehtap Kılıç, Gail B. Mahady, Sanja Vlaisavljevic, Marcello Iriti, Farzad Kobarfard, William N. Setzer, Seyed Abdulmajid Ayatollahi, Athar Ata and Javad Sharifi-Rad
9	Review: Noncoding RNA:RNA Regulatory Networks in Cancer by Jia Jia Chan and Yvonne Tay
5	Review: PPAR Agonists and Metabolic Syndrome: An Established Role? by Margherita Botta, Matteo Audano, Amirhossein Sahebkar, Cesare R. Sirtori, Nico Mitro and Massimiliano Ruscica
4	Review: Transplantable Melanomas in Hamsters and Gerbils as Models for Human Melanoma. Sensitization in Melanoma Radiotherapy—From Animal Models to Clinical Trials by Martyna Śniegocka, Ewa Podgórska, Przemysław M. Płonka, Martyna Elas, Bożena Romanowska-Dixon, Małgorzata Szczygieł, Michał A. Żmijewski, Mirosława Cichorek, Anna Markiewicz, Anna A. Brożyna, Andrzej T. Słominski and Krystyna Urbańska
4	Review: The Double Face of Exosome-Carried MicroRNAs in Cancer Immunomodulation by Romina Alfonsi, Ludovica Grassi, Michele Signore and Désirée Bonci
4	Review: Protein–Protein Interactions with Connexin 43: Regulation and Function by Paul L. Sorgen, Andrew J. Trease, Gaelle Spagnol, Mario Delmar and Morten S. Nielsen
4	Review: Molecular Pharmacology of VEGF-A Isoforms: Binding and Signalling at VEGFR2 by Chloe J. Peach, Viviane W. Mignone, Maria Augusta Arruda, Diana C. Alcobia, Stephen J. Hill, Laura E. Kilpatrick and Jeanette Woolard
4	Review: Microbiome-Gut-Brain Axis and Toll-Like Receptors in Parkinson’s Disease by Valentina Caputi and Maria Cecilia Giron
3	Review: TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer by Laia Caja, Francesco Dituri, Serena Mancarella, Daniel Caballero-Diaz, Aristidis Moustakas, Gianluigi Giannelli and Isabel Fabregat
3	Review: Resistance to Anti-Angiogenic Therapy in Cancer—Alterations to Anti-VEGF Pathway by Yoshiro Itatani, Kenji Kawada, Takamasa Yamamoto and Yoshiharu Sakai

Citations	Article
15	Review: Medicinal Plants Used in the Treatment of Human Immunodeficiency Virus by Bahare Salehi, Nanjangud V. Anil Kumar, Bilge Şener, Mehdi Sharifi-Rad, Mehtap Kılıç, Gail B. Mahady, Sanja Vlaisavljevic, Marcello Iriti, Farzad Kobarfard, William N. Setzer, Seyed Abdulmajid Ayatollahi, Athar Ata and Javad Sharifi-Rad
14	Review: Recent Advances in SELEX Technology and Aptamer Applications in Biomedicine by Zhenjian Zhuo, Yuanyuan Yu, Maolin Wang, Jie Li, Zongkang Zhang, Jin Liu, Xiaohao Wu, Aiping Lu, Ge Zhang and Baoting Zhang
14	Review: Zinc in Cellular Regulation: The Nature and Significance of “Zinc Signals” by Wolfgang Maret
13	Review: Drug Resistance Driven by Cancer Stem Cells and Their Niche by Marta Prieto-Vila, Ryou-u Takahashi, Wataru Usuba, Isaku Kohama and Takahiro Ochiya
12	Review: The Role of Resveratrol in Cancer Therapy by Jeong-Hyeon Ko, Gautam Sethi, Jae-Young Um, Muthu K Shanmugam, Frank Arfuso, Alan Prem Kumar, Anupam Bishayee and Kwang Seok Ahn
12	Review: Targeting Immune Cell Checkpoints during Sepsis by Naeem K. Patil, Yin Guo, Liming Luan and Edward R. Sherwood
11	Review: Apoptosis: A Target for Anticancer Therapy by Claire M. Pfeffer and Amareshwar T. K. Singh
10	Review: Plant Secondary Metabolites as Anticancer Agents: Successes in Clinical Trials and Therapeutic Application by Ana M. L. Seca and Diana C. G. A. Pinto
10	Article: *The Complete Chloroplast Genome Sequences of the Medicinal Plant Forsythia suspensa* (Oleaceae)** by Wenbin Wang, Huan Yu, Jiahui Wang, Wanjun Lei, Jianhua Gao, Xiangpo Qiu and Jinsheng Wang
10	Review: Impact of Omega-3 Fatty Acids on the Gut Microbiota by Lara Costantini, Romina Molinari, Barbara Farinon and Nicolò Merendino

Citations	Article
63	Review: Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer by Inés Mármol, Cristina Sánchez-de-Diego, Alberto Pradilla Dieste, Elena Cerrada and María Jesús Rodriguez Yoldi
61	Review: MicroRNA in Control of Gene Expression: An Overview of Nuclear Functions by Caterina Catalanotto, Carlo Cogoni and Giuseppe Zardo
50	Review: Histone Deacetylase Inhibitors as Anticancer Drugs by Tomas Eckschlager, Johana Plch, Marie Stiborova and Jan Hrabeta
47	Review: Melatonin: A Mitochondrial Targeting Molecule Involving Mitochondrial Protection and Dynamics by Dun-Xian Tan, Lucien C. Manchester, Lilan Qin and Russel J. Reiter
38	Review: Next-Generation Sequencing in Oncology: Genetic Diagnosis, Risk Prediction and Cancer Classification by Rick Kamps, Rita D. Brandão, Bianca J. van den Bosch, Aimee D. C. Paulussen, Sofia Xanthoulea, Marinus J. Blok and Andrea Romano
36	Review: Exosomes: From Garbage Bins to Promising Therapeutic Targets by Mohammed H. Rashed, Emine Bayraktar, Gouda K. Helal, Mohamed F. Abd-Ellah, Paola Amero, Arturo Chavez-Reyes and Cristian Rodriguez-Aguayo
36	Review: Future Prospects for Scaffolding Methods and Biomaterials in Skin Tissue Engineering: A Review by Atul A. Chaudhari, Komal Vig, Dieudonné Radé Baganizi, Rajnish Sahu, Saurabh Dixit, Vida Dennis, Shree Ram Singh and Shreekumar R. Pillai
34	Review: Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis by Russel J. Reiter, Sergio A. Rosales-Corral, Dun-Xian Tan, Dario Acuna-Castroviejo, Lilan Qin, Shun-Fa Yang and Kexin Xu
34	Review: Parkinson’s Disease: From Pathogenesis to Pharmacogenomics by Ramón Cacabelos
33	Review: The Role of Reactive Oxygen Species (ROS) in the Biological Activities of Metallic Nanoparticles by Ahmed Abdal Dayem, Mohammed Kawser Hossain, Soo Bin Lee, Kyeongseok Kim, Subbroto Kumar Saha, Gwang-Mo Yang, Hye Yeon Choi and Ssang-Goo Cho

Citations	Article
168	Review: The Role of Oxidative Stress and Antioxidants in Liver Diseases by Sha Li, Hor-Yue Tan, Ning Wang, Zhang-Jin Zhang, Lixing Lao, Chi-Woon Wong and Yibin Feng
112	Review: Silver Nanoparticles: Synthesis, Characterization, Properties, Applications, and Therapeutic Approaches by Xi-Feng Zhang, Zhi-Guo Liu, Wei Shen and Sangiliyandi Gurunathan
104	Review: Diabetic Cardiovascular Disease Induced by Oxidative Stress by Yosuke Kayama, Uwe Raaz, Ann Jagger, Matti Adam, Isabel N. Schellinger, Masaya Sakamoto, Hirofumi Suzuki, Kensuke Toyama, Joshua M. Spin and Philip S. Tsao
99	Review: Bioactive Compounds and Antioxidant Activity in Different Types of Berries by Sona Skrovankova, Daniela Sumczynski, Jiri Mlcek, Tunde Jurikova and Jiri Sochor
93	Review: Focus on Extracellular Vesicles: Introducing the Next Small Big Thing by Hina Kalra, Gregor P. C. Drummen and Suresh Mathivanan
80	Review: Endoplasmic Reticulum Stress and Associated ROS by Hafiz Maher Ali Zeeshan, Geum Hwa Lee, Hyung-Ryong Kim and Han-Jung Chae
79	Review: RUCAM in Drug and Herb Induced Liver Injury: The Update by Gaby Danan and Rolf Teschke
78	Review: Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis by Hyun Sook Hwang and Hyun Ah Kim
77	Review: Focus on Extracellular Vesicles: New Frontiers of Cell-to-Cell Communication in Cancer by Chiara Ciardiello, Lorenzo Cavallini, Cristiana Spinelli, Julie Yang, Mariana Reis-Sobreiro, Paola de Candia, Valentina Renè Minciacchi and Dolores Di Vizio
75	Review: Insights into Protein–Ligand Interactions: Mechanisms, Models, and Methods by Xing Du, Yi Li, Yuan-Ling Xia, Shi-Meng Ai, Jing Liang, Peng Sang, Xing-Lai Ji and Shu-Qun Liu

» More Articles

Views	Article
41314	Review: Structural DNA Nanotechnology: From Design to Applications by Reza M. Zadegan and Michael L. Norton
22067	Review: The Capabilities of Chaos and Complexity by David L. Abel
21830	Review: Pretreatment of Lignocellulosic Wastes to Improve Ethanol and Biogas Production: A Review by Mohammad J. Taherzadeh and Keikhosro Karimi
20534	Review: Impact of Dietary Polyphenols on Carbohydrate Metabolism by Kati Hanhineva, Riitta Törrönen, Isabel Bondia-Pons, Jenna Pekkinen, Marjukka Kolehmainen, Hannu Mykkänen and Kaisa Poutanen
19603	Review: An Updated Review of Tyrosinase Inhibitors by Te-Sheng Chang
19410	Review: *Quantum Dots for Live Cell and In Vivo* Imaging** by Maureen A. Walling, Jennifer A. Novak and Jason R. E. Shepard
19383	Review: Biodegradability of Plastics by Yutaka Tokiwa, Buenaventurada P. Calabia, Charles U. Ugwu and Seiichi Aiba
17630	Review: Flavanols and Anthocyanins in Cardiovascular Health: A Review of Current Evidence by Sonia De Pascual-Teresa, Diego A. Moreno and Cristina García-Viguera
17610	Review: Dietary Polyphenols and Their Biological Significance by Xiuzhen Han, Tao Shen and Hongxiang Lou
17274	Review: Biological Activities of Polyphenols from Grapes by En-Qin Xia, Gui-Fang Deng, Ya-Jun Guo and Hua-Bin Li

Views	Article
7725	Article: β-Hydroxybutyrate Elicits Favorable Mitochondrial Changes in Skeletal Muscle by Brian A. Parker, Chase M. Walton, Sheryl T. Carr, Jacob L. Andrus, Eric C. K. Cheung, Michael J. Duplisea, Esther K. Wilson, Carrie Draney, Daniel R. Lathen, Kyle B. Kenner, David M. Thomson, Jeffery S. Tessem and Benjamin T. Bikman
3260	Review: Recognizing Depression from the Microbiota–Gut–Brain Axis by Shan Liang, Xiaoli Wu, Xu Hu, Tao Wang and Feng Jin
3239	Review: Molecular Pharmacology of VEGF-A Isoforms: Binding and Signalling at VEGFR2 by Chloe J. Peach, Viviane W. Mignone, Maria Augusta Arruda, Diana C. Alcobia, Stephen J. Hill, Laura E. Kilpatrick and Jeanette Woolard
2441	Review: Applications of CRISPR/Cas System to Bacterial Metabolic Engineering by Suhyung Cho, Jongoh Shin and Byung-Kwan Cho
2431	Review: Recent Advances in Prostate Cancer Treatment and Drug Discovery by Ekaterina Nevedomskaya, Simon J. Baumgart and Bernard Haendler
2098	Review: The Role of miRNAs in Virus-Mediated Oncogenesis by Zuzana Vojtechova and Ruth Tachezy
2050	Review: Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting by Maria Elisabeth Street, Sabrina Angelini, Sergio Bernasconi, Ernesto Burgio, Alessandra Cassio, Cecilia Catellani, Francesca Cirillo, Annalisa Deodati, Enrica Fabbrizi, Vassilios Fanos, Giancarlo Gargano, Enzo Grossi, Lorenzo Iughetti, Pietro Lazzeroni, Alberto Mantovani, Lucia Migliore, Paola Palanza, Giancarlo Panzica, Anna Maria Papini, Stefano Parmigiani, Barbara Predieri, Chiara Sartori, Gabriele Tridenti and Sergio Amarri
2040	Review: Cancer Immunotherapy: A Focus on the Regulation of Immune Checkpoints by Tao Shi, Yanyu Ma, Lingfeng Yu, Jiaxuan Jiang, Sunan Shen, Yayi Hou and Tingting Wang
1975	Review: Microbiome-Gut-Brain Axis and Toll-Like Receptors in Parkinson’s Disease by Valentina Caputi and Maria Cecilia Giron
1929	Review: Role of Magnesium Deficiency in Promoting Atherosclerosis, Endothelial Dysfunction, and Arterial Stiffening as Risk Factors for Hypertension by Krasimir Kostov and Lyudmila Halacheva

Views	Article
7967	Review: Sexually Dimorphic Outcomes after Neonatal Stroke and Hypoxia-Ischemia by Christiane Charriaut-Marlangue, Valérie C. Besson and Olivier Baud
7725	Article: β-Hydroxybutyrate Elicits Favorable Mitochondrial Changes in Skeletal Muscle by Brian A. Parker, Chase M. Walton, Sheryl T. Carr, Jacob L. Andrus, Eric C. K. Cheung, Michael J. Duplisea, Esther K. Wilson, Carrie Draney, Daniel R. Lathen, Kyle B. Kenner, David M. Thomson, Jeffery S. Tessem and Benjamin T. Bikman
4857	Review: *Essential Oils from Neotropical Piper* Species and Their Biological Activities** by Joyce Kelly da Silva, Rafaela da Trindade, Nayara Sabrina Alves, Pablo Luís Figueiredo, José Guilherme S. Maia and William N. Setzer
4339	Review: Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils by Tzu-Kai Lin, Lily Zhong and Juan Luis Santiago
3260	Review: Recognizing Depression from the Microbiota–Gut–Brain Axis by Shan Liang, Xiaoli Wu, Xu Hu, Tao Wang and Feng Jin
3239	Review: Molecular Pharmacology of VEGF-A Isoforms: Binding and Signalling at VEGFR2 by Chloe J. Peach, Viviane W. Mignone, Maria Augusta Arruda, Diana C. Alcobia, Stephen J. Hill, Laura E. Kilpatrick and Jeanette Woolard
3213	Review: Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System by Shenglong Zou and Ujendra Kumar
3119	Review: Role of the IL-23/IL-17 Axis in Psoriasis and Psoriatic Arthritis: The Clinical Importance of Its Divergence in Skin and Joints by Marie-Astrid Boutet, Alessandra Nerviani, Gabriele Gallo Afflitto and Costantino Pitzalis
3018	Review: Impact of Omega-3 Fatty Acids on the Gut Microbiota by Lara Costantini, Romina Molinari, Barbara Farinon and Nicolò Merendino
2949	Review: Analgesic Mechanisms of Antidepressants for Neuropathic Pain by Hideaki Obata

Views	Article
7990	Review: Endocannabinod Signal Dysregulation in Autism Spectrum Disorders: A Correlation Link between Inflammatory State and Neuro-Immune Alterations by Anna Lisa Brigida, Stephen Schultz, Mariana Cascone, Nicola Antonucci and Dario Siniscalco
7967	Review: Sexually Dimorphic Outcomes after Neonatal Stroke and Hypoxia-Ischemia by Christiane Charriaut-Marlangue, Valérie C. Besson and Olivier Baud
7725	Article: β-Hydroxybutyrate Elicits Favorable Mitochondrial Changes in Skeletal Muscle by Brian A. Parker, Chase M. Walton, Sheryl T. Carr, Jacob L. Andrus, Eric C. K. Cheung, Michael J. Duplisea, Esther K. Wilson, Carrie Draney, Daniel R. Lathen, Kyle B. Kenner, David M. Thomson, Jeffery S. Tessem and Benjamin T. Bikman
5960	Review: Immunomodulatory Function of the Tumor Suppressor p53 in Host Immune Response and the Tumor Microenvironment by Yan Cui and Gang Guo
5875	Review: Current Concepts of ARDS: A Narrative Review by Michele Umbrello, Paolo Formenti, Luca Bolgiaghi and Davide Chiumello
5115	Review: A Review of Gaucher Disease Pathophysiology, Clinical Presentation and Treatments by Jérôme Stirnemann, Nadia Belmatoug, Fabrice Camou, Christine Serratrice, Roseline Froissart, Catherine Caillaud, Thierry Levade, Leonardo Astudillo, Jacques Serratrice, Anaïs Brassier, Christian Rose, Thierry Billette de Villemeur and Marc G. Berger
4963	Review: Autophagy and Microglia: Novel Partners in Neurodegeneration and Aging by Ainhoa Plaza-Zabala, Virginia Sierra-Torre and Amanda Sierra
4932	Article: Cannabidiol Modulates the Expression of Alzheimer’s Disease-Related Genes in Mesenchymal Stem Cells by Rosaliana Libro, Francesca Diomede, Domenico Scionti, Adriano Piattelli, Gianpaolo Grassi, Federica Pollastro, Placido Bramanti, Emanuela Mazzon and Oriana Trubiani
4896	Review: Next-Generation Sequencing in Oncology: Genetic Diagnosis, Risk Prediction and Cancer Classification by Rick Kamps, Rita D. Brandão, Bianca J. van den Bosch, Aimee D. C. Paulussen, Sofia Xanthoulea, Marinus J. Blok and Andrea Romano
4857	Review: *Essential Oils from Neotropical Piper* Species and Their Biological Activities** by Joyce Kelly da Silva, Rafaela da Trindade, Nayara Sabrina Alves, Pablo Luís Figueiredo, José Guilherme S. Maia and William N. Setzer

Views	Article
8725	Article: Expression and Sequence Variants of Inflammatory Genes; Effects on Plasma Inflammation Biomarkers Following a 6-Week Supplementation with Fish Oil by Hubert Cormier, Iwona Rudkowska, Simone Lemieux, Patrick Couture and Marie-Claude Vohl
7990	Review: Endocannabinod Signal Dysregulation in Autism Spectrum Disorders: A Correlation Link between Inflammatory State and Neuro-Immune Alterations by Anna Lisa Brigida, Stephen Schultz, Mariana Cascone, Nicola Antonucci and Dario Siniscalco
7967	Review: Sexually Dimorphic Outcomes after Neonatal Stroke and Hypoxia-Ischemia by Christiane Charriaut-Marlangue, Valérie C. Besson and Olivier Baud
7859	Review: Effects of Probiotics and Synbiotics on Obesity, Insulin Resistance Syndrome, Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease: A Review of Human Clinical Trials by Maria Jose Sáez-Lara, Candido Robles-Sanchez, Francisco Javier Ruiz-Ojeda, Julio Plaza-Diaz and Angel Gil
7725	Article: β-Hydroxybutyrate Elicits Favorable Mitochondrial Changes in Skeletal Muscle by Brian A. Parker, Chase M. Walton, Sheryl T. Carr, Jacob L. Andrus, Eric C. K. Cheung, Michael J. Duplisea, Esther K. Wilson, Carrie Draney, Daniel R. Lathen, Kyle B. Kenner, David M. Thomson, Jeffery S. Tessem and Benjamin T. Bikman
7589	Book Review: Molecular Biology of the Cell, Sixth Edition; ISBN: 9780815344643; and Molecular Biology of the Cell, Sixth Edition, The Problems Book; ISBN 9780815344537 by Stephen Bustin
7102	Article: *Gap Junctional Blockade Stochastically Induces Different Species-Specific Head Anatomies in Genetically Wild-Type Girardia dorotocephala* Flatworms** by Maya Emmons-Bell, Fallon Durant, Jennifer Hammelman, Nicholas Bessonov, Vitaly Volpert, Junji Morokuma, Kaylinnette Pinet, Dany S. Adams, Alexis Pietak, Daniel Lobo and Michael Levin
6580	Review: The Role of Oxidative Stress and Antioxidants in Liver Diseases by Sha Li, Hor-Yue Tan, Ning Wang, Zhang-Jin Zhang, Lixing Lao, Chi-Woon Wong and Yibin Feng
6131	Review: Silver Nanoparticles: Synthesis, Characterization, Properties, Applications, and Therapeutic Approaches by Xi-Feng Zhang, Zhi-Guo Liu, Wei Shen and Sangiliyandi Gurunathan
5960	Review: Immunomodulatory Function of the Tumor Suppressor p53 in Host Immune Response and the Tumor Microenvironment by Yan Cui and Gang Guo

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