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Citations	Article
511	Metabolic Syndrome: Updates on Pathophysiology and Management in 2021 by Gracia Fahed, Laurence Aoun, Morgan Bou Zerdan, Sabine Allam, Maroun Bou Zerdan, Youssef Bouferraa and Hazem I. Assi
407	The MTT Assay: Utility, Limitations, Pitfalls, and Interpretation in Bulk and Single-Cell Analysis by Mahshid Ghasemi, Tyron Turnbull, Sonia Sebastian and Ivan Kempson
351	The Flavonoid Biosynthesis Network in Plants by Weixin Liu, Yi Feng, Suhang Yu, Zhengqi Fan, Xinlei Li, Jiyuan Li and Hengfu Yin
312	Gut Microbiota and Short Chain Fatty Acids: Implications in Glucose Homeostasis by Piero Portincasa, Leonilde Bonfrate, Mirco Vacca, Maria De Angelis, Ilaria Farella, Elisa Lanza, Mohamad Khalil, David Q.-H. Wang, Markus Sperandio and Agostino Di Ciaula
306	Neutrophil to Lymphocyte Ratio: An Emerging Marker of the Relationships between the Immune System and Diseases by Agata Buonacera, Benedetta Stancanelli, Michele Colaci and Lorenzo Malatino
306	Cytochrome P450 Enzymes and Drug Metabolism in Humans by Mingzhe Zhao, Jingsong Ma, Mo Li, Yingtian Zhang, Bixuan Jiang, Xianglong Zhao, Cong Huai, Lu Shen, Na Zhang, Lin He and Shengying Qin
303	Pathophysiology of Atherosclerosis by Shifa Jebari-Benslaiman, Unai Galicia-García, Asier Larrea-Sebal, Javier Rekondo Olaetxea, Iraide Alloza, Koen Vandenbroeck, Asier Benito-Vicente and César Martín
273	An Overview of Oxidative Stress, Neuroinflammation, and Neurodegenerative Diseases by Daniel Mihai Teleanu, Adelina-Gabriela Niculescu, Iulia Ioana Lungu, Crina Ioana Radu, Oana Vladâcenco, Eugenia Roza, Bogdan Costăchescu, Alexandru Mihai Grumezescu and Raluca Ioana Teleanu
221	A Review of the Common Neurodegenerative Disorders: Current Therapeutic Approaches and the Potential Role of Nanotherapeutics by Richard N. L. Lamptey, Bivek Chaulagain, Riddhi Trivedi, Avinash Gothwal, Buddhadev Layek and Jagdish Singh
216	MicroRNA-Based Diagnosis and Therapy by Phuong T. B. Ho, Ian M. Clark and Linh T. T. Le

Citations	Article
180	Lipid Peroxidation and Iron Metabolism: Two Corner Stones in the Homeostasis Control of Ferroptosis by Luc Rochette, Geoffrey Dogon, Eve Rigal, Marianne Zeller, Yves Cottin and Catherine Vergely
154	The Role of Inflammation in Cardiovascular Disease by Michael Y. Henein, Sergio Vancheri, Giovanni Longo and Federico Vancheri
125	Alzheimer’s Disease: Treatment Strategies and Their Limitations by Elodie Passeri, Kamil Elkhoury, Margaretha Morsink, Kerensa Broersen, Michel Linder, Ali Tamayol, Catherine Malaplate, Frances T. Yen and Elmira Arab-Tehrany
124	Pathophysiology of Inflammatory Bowel Disease: Innate Immune System by Angela Saez, Beatriz Herrero-Fernandez, Raquel Gomez-Bris, Hector Sánchez-Martinez and Jose M. Gonzalez-Granado
117	The Machinery of Exosomes: Biogenesis, Release, and Uptake by Sofia V. Krylova and Daorong Feng
107	Mechanisms of Oxidative Stress in Metabolic Syndrome by Sepiso K. Masenga, Lombe S. Kabwe, Martin Chakulya and Annet Kirabo
100	NANOBODIES^®: A Review of Diagnostic and Therapeutic Applications by Bo-kyung Jin, Steven Odongo, Magdalena Radwanska and Stefan Magez
99	Optimization of the Hemolysis Assay for the Assessment of Cytotoxicity by Ingvill Pedersen Sæbø, Magnar Bjørås, Henrik Franzyk, Emily Helgesen and James Alexander Booth
95	Non-Alcoholic Fatty Liver Disease (NAFLD) Pathogenesis and Natural Products for Prevention and Treatment by Xiangyu Guo, Xunzhe Yin, Zuojia Liu and Jin Wang
94	Cytokine Storm—Definition, Causes, and Implications by Dominik Jarczak and Axel Nierhaus

Citations	Article
40	Green Synthesis of Metal and Metal Oxide Nanoparticles: A Review of the Principles and Biomedical Applications by Denisa-Maria Radulescu, Vasile-Adrian Surdu, Anton Ficai, Denisa Ficai, Alexandru-Mihai Grumezescu and Ecaterina Andronescu
32	COVID-19 Complications: Oxidative Stress, Inflammation, and Mitochondrial and Endothelial Dysfunction by Ekaterina Georgieva, Julian Ananiev, Yovcho Yovchev, Georgi Arabadzhiev, Hristo Abrashev, Despina Abrasheva, Vasil Atanasov, Rositsa Kostandieva, Mitko Mitev, Kamelia Petkova-Parlapanska, Yanka Karamalakova, Iliana Koleva-Korkelia, Vanya Tsoneva and Galina Nikolova
29	Current Advances in Photodynamic Therapy (PDT) and the Future Potential of PDT-Combinatorial Cancer Therapies by Niuska Alvarez and Ana Sevilla
28	The Role of Pro-Inflammatory Cytokines in the Pathogenesis of Cardiovascular Disease by Hannah Zhang and Naranjan S. Dhalla
28	A Review of Natural Polysaccharides: Sources, Characteristics, Properties, Food, and Pharmaceutical Applications by Ikbel Benalaya, Gilberto Alves, João Lopes and Luís R. Silva
25	Emerging Translational Research in Neurological and Psychiatric Diseases: From In Vitro to In Vivo Models by Masaru Tanaka, Ágnes Szabó, László Vécsei and Lydia Giménez-Llort
24	Blood–Brain Barrier Breakdown in Alzheimer’s Disease: Mechanisms and Targeted Strategies by Amer E. Alkhalifa, Nour F. Al-Ghraiybah, Julia Odum, John G. Shunnarah, Nataleigh Austin and Amal Kaddoumi
24	Complement System and the Kidney: Its Role in Renal Diseases, Kidney Transplantation and Renal Cell Carcinoma by Francesco Lasorsa, Monica Rutigliano, Martina Milella, Matteo Ferro, Savio Domenico Pandolfo, Felice Crocetto, Simona Simone, Loreto Gesualdo, Michele Battaglia, Pasquale Ditonno and Giuseppe Lucarelli
22	Trials and Tribulations of MicroRNA Therapeutics by Attila A. Seyhan
22	The Role of Obesity in Type 2 Diabetes Mellitus—An Overview by Preethi Chandrasekaran and Ralf Weiskirchen

Citations	Article
9	The Pathophysiological, Genetic, and Hormonal Changes in Preeclampsia: A Systematic Review of the Molecular Mechanisms by Yi-Ting Chiang, Kok-Min Seow and Kuo-Hu Chen
8	The Role of Prebiotics in Modulating Gut Microbiota: Implications for Human Health by Suyeon Yoo, Suk-Chae Jung, Kihyuck Kwak and Jun-Seob Kim
8	Antimicrobial Peptides towards Clinical Application—A Long History to Be Concluded by Laura Cresti, Giovanni Cappello and Alessandro Pini
7	Heat Shock Response and Heat Shock Proteins: Current Understanding and Future Opportunities in Human Diseases by Manish Kumar Singh, Yoonhwa Shin, Songhyun Ju, Sunhee Han, Wonchae Choe, Kyung-Sik Yoon, Sung Soo Kim and Insug Kang
7	Metformin: A Dual-Role Player in Cancer Treatment and Prevention by Mariam Ahmed Galal, Mohammed Al-Rimawi, Abdurrahman Hajeer, Huda Dahman, Samhar Alouch and Ahmad Aljada
6	Optimization of Calcium Fluoride Crystallization Process for Treatment of High-Concentration Fluoride-Containing Semiconductor Industry Wastewater by Arindam Sinharoy, Ga-Young Lee and Chong-Min Chung
6	Advancements in Photothermal Therapy Using Near-Infrared Light for Bone Tumors by Mengzhang Xie, Taojun Gong, Yitian Wang, Zhuangzhuang Li, Minxun Lu, Yi Luo, Li Min, Chongqi Tu, Xingdong Zhang, Qin Zeng and Yong Zhou
6	Molecular Pathways of Genistein Activity in Breast Cancer Cells by Evangelia K. Konstantinou, Aristea Gioxari, Maria Dimitriou, George I. Panoutsopoulos and Athanasios A. Panagiotopoulos
6	Gold Nanoparticles (AuNPs)—Toxicity, Safety and Green Synthesis: A Critical Review by Łukasz Niżnik, Maciej Noga, Damian Kobylarz, Adrian Frydrych, Alicja Krośniak, Lucyna Kapka-Skrzypczak and Kamil Jurowski
6	Mechanism of Decision Making between Autophagy and Apoptosis Induction upon Endoplasmic Reticulum Stress by Orsolya Kapuy

Citations	Article
2197	Silver Nanoparticles: Synthesis, Characterization, Properties, Applications, and Therapeutic Approaches by Xi-Feng Zhang, Zhi-Guo Liu, Wei Shen and Sangiliyandi Gurunathan
2145	The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation by Nathan Kelley, Devon Jeltema, Yanhui Duan and Yuan He
2106	Pretreatment of Lignocellulosic Wastes to Improve Ethanol and Biogas Production: A Review by Mohammad J. Taherzadeh and Keikhosro Karimi
1508	Physiological, Biochemical, and Molecular Mechanisms of Heat Stress Tolerance in Plants by Mirza Hasanuzzaman, Kamrun Nahar, Md. Mahabub Alam, Rajib Roychowdhury and Masayuki Fujita
1411	UV Radiation and the Skin by John D'Orazio, Stuart Jarrett, Alexandra Amaro-Ortiz and Timothy Scott
1399	Obesity and Its Metabolic Complications: The Role of Adipokines and the Relationship between Obesity, Inflammation, Insulin Resistance, Dyslipidemia and Nonalcoholic Fatty Liver Disease by Un Ju Jung and Myung-Sook Choi
1262	Pathophysiology of Type 2 Diabetes Mellitus by Unai Galicia-Garcia, Asier Benito-Vicente, Shifa Jebari, Asier Larrea-Sebal, Haziq Siddiqi, Kepa B. Uribe, Helena Ostolaza and César Martín
1251	An Updated Review of Tyrosinase Inhibitors by Te-Sheng Chang
1249	The Role of Oxidative Stress and Antioxidants in Liver Diseases by Sha Li, Hor-Yue Tan, Ning Wang, Zhang-Jin Zhang, Lixing Lao, Chi-Woon Wong and Yibin Feng
1248	Green Extraction of Natural Products: Concept and Principles by Farid Chemat, Maryline Abert Vian and Giancarlo Cravotto

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97639	Intramyocardial Inflammation after COVID-19 Vaccination: An Endomyocardial Biopsy-Proven Case Series by Christian Baumeier, Ganna Aleshcheva, Dominik Harms, Ulrich Gross, Christian Hamm, Birgit Assmus, Ralf Westenfeld, Malte Kelm, Spyros Rammos, Philip Wenzel, Thomas Münzel, Albrecht Elsässer, Mudather Gailani, Christian Perings, Alae Bourakkadi, Markus Flesch, Tibor Kempf, Johann Bauersachs, Felicitas Escher and Heinz-Peter Schultheiss
81517	mRNA: Vaccine or Gene Therapy? The Safety Regulatory Issues by Helene Banoun
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59040	Metabolic Syndrome: Updates on Pathophysiology and Management in 2021 by Gracia Fahed, Laurence Aoun, Morgan Bou Zerdan, Sabine Allam, Maroun Bou Zerdan, Youssef Bouferraa and Hazem I. Assi
57007	Pathophysiology of Atherosclerosis by Shifa Jebari-Benslaiman, Unai Galicia-García, Asier Larrea-Sebal, Javier Rekondo Olaetxea, Iraide Alloza, Koen Vandenbroeck, Asier Benito-Vicente and César Martín
55387	Understanding the Pharmacology of COVID-19 mRNA Vaccines: Playing Dice with the Spike? by Marco Cosentino and Franca Marino
45201	*Concurrent Infection of the Human Brain with Multiple Borrelia* Species by Maryna Golovchenko, Jakub Opelka, Marie Vancova, Hana Sehadova, Veronika Kralikova, Martin Dobias, Milan Raska, Michal Krupka, Kristyna Sloupenska and Natalie Rudenko**
38781	*Acknowledgment to the Reviewers of International Journal of Molecular Sciences* in 2022 by IJMS Editorial Office**
38153	Melatonin: Regulation of Viral Phase Separation and Epitranscriptomics in Post-Acute Sequelae of COVID-19 by Doris Loh and Russel J. Reiter
37619	The MTT Assay: Utility, Limitations, Pitfalls, and Interpretation in Bulk and Single-Cell Analysis by Mahshid Ghasemi, Tyron Turnbull, Sonia Sebastian and Ivan Kempson

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81517	mRNA: Vaccine or Gene Therapy? The Safety Regulatory Issues by Helene Banoun
61680	SARS-CoV-2 Spike Protein Induces Hemagglutination: Implications for COVID-19 Morbidities and Therapeutics and for Vaccine Adverse Effects by Celine Boschi, David E. Scheim, Audrey Bancod, Muriel Militello, Marion Le Bideau, Philippe Colson, Jacques Fantini and Bernard La Scola
45201	*Concurrent Infection of the Human Brain with Multiple Borrelia* Species by Maryna Golovchenko, Jakub Opelka, Marie Vancova, Hana Sehadova, Veronika Kralikova, Martin Dobias, Milan Raska, Michal Krupka, Kristyna Sloupenska and Natalie Rudenko**
38781	*Acknowledgment to the Reviewers of International Journal of Molecular Sciences* in 2022 by IJMS Editorial Office**
34700	Acute Exposure to Microplastics Induced Changes in Behavior and Inflammation in Young and Old Mice by Lauren Gaspar, Sydney Bartman, Giuseppe Coppotelli and Jaime M. Ross
27746	Pathophysiology of Inflammatory Bowel Disease: Innate Immune System by Angela Saez, Beatriz Herrero-Fernandez, Raquel Gomez-Bris, Hector Sánchez-Martinez and Jose M. Gonzalez-Granado
27423	Light, Water, and Melatonin: The Synergistic Regulation of Phase Separation in Dementia by Doris Loh and Russel J. Reiter
26045	Lifetime Evaluation of Left Ventricular Structure and Function in Male C57BL/6J Mice after Gamma and Space-Type Radiation Exposure by Agnieszka Brojakowska, Cedric J. Jackson, Malik Bisserier, Mary K. Khlgatian, Cynthia Grano, Steve R. Blattnig, Shihong Zhang, Kenneth M. Fish, Vadim Chepurko, Elena Chepurko, Virginia Gillespie, Ying Dai, Brooke Lee, Venkata Naga Srikanth Garikipati, Lahouaria Hadri, Raj Kishore and David A. Goukassian
25926	Influence of Solvent Polarity on the Conformer Ratio of Bicalutamide in Saturated Solutions: Insights from NOESY NMR Analysis and Quantum-Chemical Calculations by Valentina V. Sobornova, Konstantin V. Belov, Michael A. Krestyaninov and Ilya A. Khodov
25721	Salbutamol in the Management of Asthma: A Review by Lara Marques and Nuno Vale

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45201	*Concurrent Infection of the Human Brain with Multiple Borrelia* Species by Maryna Golovchenko, Jakub Opelka, Marie Vancova, Hana Sehadova, Veronika Kralikova, Martin Dobias, Milan Raska, Michal Krupka, Kristyna Sloupenska and Natalie Rudenko**
25926	Influence of Solvent Polarity on the Conformer Ratio of Bicalutamide in Saturated Solutions: Insights from NOESY NMR Analysis and Quantum-Chemical Calculations by Valentina V. Sobornova, Konstantin V. Belov, Michael A. Krestyaninov and Ilya A. Khodov
19823	Hydrogen Water: Extra Healthy or a Hoax?—A Systematic Review by Gagandeep Dhillon, Venkata Buddhavarapu, Harpreet Grewal, Pranjal Sharma, Ram Kishun Verma, Ripudaman Munjal, Ramprakash Devadoss and Rahul Kashyap
15867	Mitochondrial Dysfunction and Coenzyme Q10 Supplementation in Post-Viral Fatigue Syndrome: An Overview by David Mantle, Iain Parry Hargreaves, Joan Carles Domingo and Jesus Castro-Marrero
13691	An Overview of Recent Developments in the Management of Burn Injuries by Elżbieta Radzikowska-Büchner, Inga Łopuszyńska, Wojciech Flieger, Michał Tobiasz, Ryszard Maciejewski and Jolanta Flieger
13274	Ketosis Suppression and Ageing (KetoSAge): The Effects of Suppressing Ketosis in Long Term Keto-Adapted Non-Athletic Females by Isabella D. Cooper, Yvoni Kyriakidou, Kurtis Edwards, Lucy Petagine, Thomas N. Seyfried, Tomas Duraj, Adrian Soto-Mota, Andrew Scarborough, Sandra L. Jacome, Kenneth Brookler, Valentina Borgognoni, Vanusa Novaes, Rima Al-Faour and Bradley T. Elliott
12903	SARS-CoV-2 Rapidly Infects Peripheral Sensory and Autonomic Neurons, Contributing to Central Nervous System Neuroinvasion before Viremia by Jonathan D. Joyce, Greyson A. Moore, Poorna Goswami, Telvin L. Harrell, Tina M. Taylor, Seth A. Hawks, Jillian C. Green, Mo Jia, Matthew D. Irwin, Emma Leslie, Nisha K. Duggal, Christopher K. Thompson and Andrea S. Bertke
11631	Plant Extracts as Skin Care and Therapeutic Agents by Monika Michalak
11609	The Role of Obesity in Type 2 Diabetes Mellitus—An Overview by Preethi Chandrasekaran and Ralf Weiskirchen
11577	The Relationships between Intestinal Permeability and Target Antibodies for a Spectrum of Autoimmune Diseases by Datis Kharrazian, Martha Herbert and Jama Lambert

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25926	Influence of Solvent Polarity on the Conformer Ratio of Bicalutamide in Saturated Solutions: Insights from NOESY NMR Analysis and Quantum-Chemical Calculations by Valentina V. Sobornova, Konstantin V. Belov, Michael A. Krestyaninov and Ilya A. Khodov
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9166	Targeting the High-Density Lipoprotein Proteome for the Treatment of Post-Acute Sequelae of SARS-CoV-2 by Karsten Grote, Ann-Christin Schaefer, Muhidien Soufi, Volker Ruppert, Uwe Linne, Aditya Mukund Bhagwat, Witold Szymanski, Johannes Graumann, Yana Gercke, Sümeya Aldudak, Denise Hilfiker-Kleiner, Elisabeth Schieffer and Bernhard Schieffer
7733	Sex and Gender Differences in Alzheimer’s Disease: Genetic, Hormonal, and Inflammation Impacts by Zahra Kolahchi, Nicholas Henkel, Mahmoud A. Eladawi, Emma C. Villarreal, Prathik Kandimalla, Anna Lundh, Robert E. McCullumsmith and Elvis Cuevas
7108	Renin–Angiotensin–Aldosterone System: From History to Practice of a Secular Topic by Sara H. Ksiazek, Lilio Hu, Sebastiano Andò, Markus Pirklbauer, Marcus D. Säemann, Chiara Ruotolo, Gianluigi Zaza, Gaetano La Manna, Luca De Nicola, Gert Mayer and Michele Provenzano
6400	Revealing the Hidden Impacts: Insights into Biological Aging and Long-Term Effects in Pauci- and Asymptomatic COVID-19 Healthcare Workers by Manuela Campisi, Luana Cannella, Anna Bordin, Angelo Moretto, Maria Luisa Scapellato, Paola Mason, Filippo Liviero, Sofia Pavanello and on behalf of Occupational Medicine Working Group
5098	Assessment of Thyroid Carcinogenic Risk and Safety Profile of GLP1-RA Semaglutide (Ozempic) Therapy for Diabetes Mellitus and Obesity: A Systematic Literature Review by Catalin Vladut Ionut Feier, Razvan Constantin Vonica, Alaviana Monique Faur, Diana Raluca Streinu and Calin Muntean
4565	Effects of Probiotics on Gut Microbiota: An Overview by Preethi Chandrasekaran, Sabine Weiskirchen and Ralf Weiskirchen
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184837	Pathophysiology of Type 2 Diabetes Mellitus by Unai Galicia-Garcia, Asier Benito-Vicente, Shifa Jebari, Asier Larrea-Sebal, Haziq Siddiqi, Kepa B. Uribe, Helena Ostolaza and César Martín
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105021	The Pathophysiology of Gestational Diabetes Mellitus by Jasmine F Plows, Joanna L Stanley, Philip N Baker, Clare M Reynolds and Mark H Vickers
97639	Intramyocardial Inflammation after COVID-19 Vaccination: An Endomyocardial Biopsy-Proven Case Series by Christian Baumeier, Ganna Aleshcheva, Dominik Harms, Ulrich Gross, Christian Hamm, Birgit Assmus, Ralf Westenfeld, Malte Kelm, Spyros Rammos, Philip Wenzel, Thomas Münzel, Albrecht Elsässer, Mudather Gailani, Christian Perings, Alae Bourakkadi, Markus Flesch, Tibor Kempf, Johann Bauersachs, Felicitas Escher and Heinz-Peter Schultheiss
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21360	Metabolic Syndrome: Updates on Pathophysiology and Management in 2021 by Gracia Fahed, Laurence Aoun, Morgan Bou Zerdan, Sabine Allam, Maroun Bou Zerdan, Youssef Bouferraa and Hazem I. Assi
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15251	Advances in Lipid Extraction Methods—A Review by Ramesh Kumar Saini, Parchuri Prasad, Xiaomin Shang and Young-Soo Keum
14779	Polycystic Ovary Syndrome: A Comprehensive Review of Pathogenesis, Management, and Drug Repurposing by Hosna Mohammad Sadeghi, Ida Adeli, Daniela Calina, Anca Oana Docea, Taraneh Mousavi, Marzieh Daniali, Shekoufeh Nikfar, Aristidis Tsatsakis and Mohammad Abdollahi
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10445	The Role of Telomerase in Breast Cancer’s Response to Therapy by Eliza Judasz, Natalia Lisiak, Przemysław Kopczyński, Magdalena Taube and Błażej Rubiś
7754	Mendelian Randomization Studies of Lifestyle-Related Risk Factors for Osteoarthritis: A PRISMA Review and Meta-Analysis by Justin Ho, Christopher Chi Hang Mak, Vivek Sharma, Kendrick To and Wasim Khan
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3631	Autoimmune Hemolytic Anemias: Classifications, Pathophysiology, Diagnoses and Management by Melika Loriamini, Christine Cserti-Gazdewich and Donald R. Branch
3584	Drug Therapies for Diabetes by Roni Weinberg Sibony, Omri Segev, Saar Dor and Itamar Raz
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3631	Autoimmune Hemolytic Anemias: Classifications, Pathophysiology, Diagnoses and Management by Melika Loriamini, Christine Cserti-Gazdewich and Donald R. Branch
1992	Hypertension and Heart Failure: From Pathophysiology to Treatment by Giovanna Gallo and Carmine Savoia
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