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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Insights into the Immunopathology of Infectious Diseases

edited by Marta Camici

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4236 | Submission Open

Keywords: infection immunology; immune dysregulation in infectious diseases; interactions between infective agents and immune responses; modeling of the immune system; new pathways of pathogenesis

(This special issue belongs to the Section Molecular Immunology)

Molecular Toxicity of Foodstuff Contaminants and Mitigation Strategies

edited by

Lihong Zhao

and Matthew Koci

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4231 | Submission Open

Keywords: antibiotics; heavy metals; pesticides; mycotoxins; foodborne pathogens; polycyclic aromatic hydrocarbons; microplastics; toxicity; biodegradation; detoxification

(This special issue belongs to the Section Molecular Toxicology)

Novel Insights into Regenerative Medicine

edited by

Jorge U. Carmona

and

Marco Tatullo

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4162 | Submission Open

Keywords: regenerative medicine; tissue regeneration; stem cell; platelet-rich plasma; growth factors; cytokines; bioscaffolds; gels

(This special issue belongs to the Section Materials Science)

The Effect of Food-Derived Compounds on Brown Fat Cell Function

edited by

Nobuyuki Takahashi

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4048 | Submission Open

Keywords: brown adipocyte; beige adipocyte; nutrients; food-derived components; thermogenesis; energy homeostasis; inflammation; obesity; diabetes; insulin resistance; metabolic syndrome; adipokines; lipid and carbohydrate metabolism

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research on Amyloidosis in Pathobiology and Therapy

edited by

Kazufumi Nakamura

submission deadline 20 Jul 2025 | 1 articles | Viewed by 4007 | Submission Open

Keywords: amyloidosis; ATTR; transthyretin; misfolding; molecular mechanisms; molecular therapeutic targets; molecular imaging; SPECT; tracers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Investigating Host-Parasite Interactions for the Discovery of Novel Therapies and Vaccine Targets

edited by

Natalie Nieuwenhuizen

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3929 | Submission Open

Keywords: parasites; host-pathogen interactions; helminths; worms; protozoans; leishmania; malaria; schistosomiasis; trypanosomiasis; ascariasis; anisakiasis; vectors; mosquitoes; ticks; neglected tropical diseases

(This special issue belongs to the Section Molecular Immunology)

Molecular Research in Fruit Crop: Second Edition

edited by

Chen Wang

submission deadline 20 Jul 2025 | 3 articles | Viewed by 3904 | Submission Open

Keywords: fruit crop; biotechnology; hormonal; environmental signals

(This special issue belongs to the Section Molecular Plant Sciences)

Lipidomics and Lipid Metabolism in Health and Disease

edited by

Dimiter Avtanski

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3899 | Submission Open

Keywords: lipidomics; lipid metabolism; lipid signaling; lipid homeostasis; metabolic disease; lipid biomarkers; fatty acids; phospholipids; sphingolipids; cholesterol

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Recent Advances in Human Papillomavirus (HPV) Research

edited by

Jane Shen-Gunther

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3826 | Submission Open

Keywords: human papillomavirus (HPV)/genetics; HPV-associated cancers; HPV cell-free DNA (cfDNA); HPV circulating tumor DNA (ctDNA); HPV circulating tumor cells (CTCs); carcinogenesis/genetics; CRISPR-cas systems/genetics; digital PCR; molecular diagnostics/methods; point-of-care diagnostics/methods; next-generation sequencing/methods; single-cell sequencing/methods; genomics; epigenomics; proteomics; metagenomics; phylogenomics; virus evolution; virus– host interactions; virus integration/genetics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

From Molecules to Medicines: Exploring Neurodegenerative Pathways for Targeted Neuropharmacology

edited by

Malgorzata Zaremba

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3817 | Submission Open

Keywords: disease modeling; drug studies; therapeutic interventions; neuropharmacology; innovative pharmacological interventions

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Molecular Mechanisms of Neurodegenerative Diseases

edited by Aslihan Ugun-Klusek

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3801 | Submission Open

Keywords: neurodegeneration; Parkinson’ s disease; Alzheimer’ s disease; molecular signalling; neuronal death

(This special issue belongs to the Section Molecular Neurobiology)

Post-transcriptional and Epigenetic Mechanisms Controlling Stem Cells Differentiation

edited by

Sorina Dinescu

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3788 | Submission Open

Keywords: stem cell differentiation; adipogenesis; neurogenesis; epigenetics; post-transcriptional modification; ncRNAs

(This special issue belongs to the Section Molecular Biology)

Nanoparticles in Inhaled Drug Delivery

edited by

Nazrul Islam

submission deadline 20 Jul 2025 | 1 articles | Viewed by 3775 | Submission Open

Keywords: inhaled nanoparticles; inhaled antibacterial formulations and delivery; inhaled anticancer drugs; polymeric drug nanoparticles for lung delivery; controlled release of inhalable antibacterial/anticancer drugs and their toxicity

(This special issue belongs to the Section Materials Science)

Molecular Dynamics Simulations and Structural Analysis of Protein Domains (2nd Edition)

edited by

Alexandre G. De Brevern

submission deadline 20 Jul 2025 | 5 articles | Viewed by 3775 | Submission Open

Keywords: protein structures; molecular dynamics; advanced molecular dynamics; variants; pathologies; drug design; allostery; protein domains; secondary structures; methodological development; protein design; ligands; normal mode analysis; machine learning

(This special issue belongs to the Section Molecular Informatics)

Optimizing Mechanistic Rationale for Parkinson’s Disease Treatment

edited by Michael Salvatore and Jason Richardson

submission deadline 20 Jul 2025 | 1 articles | Viewed by 3709 | Submission Open

Keywords: substantia nigra; tyrosine hydroxylase; growth factors; neuroprotection; repurposed drugs; lifestyle interventions; dopamine; models of Parkinson’ s disease

(This special issue belongs to the Section Molecular Neurobiology)

Role of Diet and Nutrition in Metabolic Diseases

edited by

Fernando Guerrero-Romero

submission deadline 20 Jul 2025 | 1 articles | Viewed by 3682 | Submission Open

Keywords: nutrients; biomarkers; molecular targets; pahodiagnosis; treatment

(This special issue belongs to the Section Bioactives and Nutraceuticals)

New Therapies for Acute Myeloid Leukemia

edited by

Eduardo Anguita

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3645 | Submission Open

Keywords: acute myeloid leukemia; BCL2 inhibitors; leukemic cells; new therapies for AML; prognostic implications

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insight into Oxidative Stress in Plants

edited by

Agnieszka Hanaka

and

Sylwia Zielińska

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3478 | Submission Open

Keywords: ROS detoxification pathways; enzymatic and non-enzymatic antioxidants; SOS markers at the molecular level; cross-talk of ROS with phytohormones; restoration of plant cell homeostasis; mechanisms of oxidative damages and antioxidant protection; multiple signaling cascades in SOS prevention; transcriptomic analysis in gene regulatory networks; metabolomic and proteomic analyses

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Phytochemicals in Neurological Disorders

edited by

Alessandro Attanzio

Antonio Cilla

and

Antonio González-Sarrías

submission deadline 20 Jul 2025 | 1 articles | Viewed by 3425 | Submission Open

Keywords: phytochemicals; neurodegeneration; antioxidant activity; anti-inflammatory activity; nutrition; bioactive; inhibitor; functional foods; nutraceuticals; molecular mechanism

(This special issue belongs to the Section Bioactives and Nutraceuticals)

MAPK Signaling Cascades in Human Health and Diseases, 2nd Edition

edited by Galia Maik-Rachline

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3408 | Submission Open

Keywords: ERK1/2; p38; JNK; ERK5; MEK; MEKK; raf; stimulated nuclear translocation; targeted therapy; resistance mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cancer: Molecular Research and Novel Inflammatory Targets

edited by

Sarah Adriana Scuderi

and

Alessia Filippone

submission deadline 20 Jul 2025 | 3 articles | Viewed by 3403 | Submission Open

Keywords: cancer; tumor microenvironment; molecular biology; biomarkers; novel and alternative therapies; inflammation; pharmacological inhibitors

(This special issue belongs to the Section Molecular Oncology)

Programmed Cell Death and Oxidative Stress: 3rd Edition

edited by

Takuya Noguchi

submission deadline 20 Jul 2025 | 3 articles | Viewed by 3385 | Submission Open

Keywords: oxidative stress; programmed cell death; cellular stresses; senescence; cytotoxicity; cancer; neurodegenerative disease; inflammatory disease; organelle stress

(This special issue belongs to the Section Biochemistry)

Unraveling Sugar Signaling: Insights into Plant Stress Responses

edited by

Claudia Uhde-Stone

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3348 | Submission Open

Keywords: sugar signaling; glucose signaling; sucrose signaling; signal transduction pathways; plant response to stress; biotic stress; abiotic stress; plant physiology

(This special issue belongs to the Section Molecular Plant Sciences)

Diabetic Bone Disease: New Insights into Molecular Mechanisms and Therapeutic Approaches

edited by

Ioannis Kanakis

submission deadline 20 Jul 2025 | 1 articles | Viewed by 3303 | Submission Open

Keywords: diabetic bone disease; molecular mechanisms; therapeutic approaches

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Natural Compounds in Human Health and Disease

edited by

Kazuhiko Nakadate

submission deadline 20 Jul 2025 | 3 articles | Viewed by 3279 | Submission Open

Keywords: nutrition; human health; obesity; polyphenol; tea; pathology; animal model

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Mechanism Based Toxicity and Hazard Assessment of NGTxC Chemicals 2.0

edited by

Miriam N. Jacobs

and

Annamaria Colacci

submission deadline 20 Jul 2025 | 1 articles | Viewed by 3232 | Submission Open

Keywords: non genotoxic carcinogens; carcinogenicity; inflammation; hazard assessment; molecular targets

(This special issue belongs to the Section Molecular Toxicology)

Inflammatory Bowel Disease and Microbiome

edited by Abigail Raffner Basson

submission deadline 20 Jul 2025 | 3 articles | Viewed by 3215 | Submission Open

Keywords: inflammatory bowel disease; Crohn’ s disease; ulcerative colitis; gut microbiota; diet; treatment; pathogenesis; biomarker

(This special issue belongs to the Section Molecular Microbiology)

Advances in Drug Discovery and Synthesis: 2nd Edition

edited by

Lidia Ciccone

and

Susanna Nencetti

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2985 | Submission Open

Keywords: medicinal chemistry; drug discovery; design and synthesis of bioactive compounds; molecular modeling; X-ray crystallography; structure– activity relationships; structure-based drug design

(This special issue belongs to the Section Molecular Pharmacology)

Biophysical Perspectives on Bone Physiology and Pathology

edited by Atsuhiko Ichimura and Yohei Ueda

submission deadline 20 Jul 2025 | 1 articles | Viewed by 2966 | Submission Open

Keywords: bone formation; bone disorders; physiology; pathology; stem cells; osteoblasts; osteoclasts

(This special issue belongs to the Section Molecular Biophysics)

Antimicrobial Resistance—New Insights, 3rd Edition

edited by

Cidália Pina-Vaz

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2959 | Submission Open

Keywords: antimicrobial resistance; mechanisms of antimicrobial resistance; rapid antimicrobial susceptible assays; antimicrobial dosing; molecular assays

(This special issue belongs to the Section Molecular Microbiology)

The Role of Nutraceuticals in Gastrointestinal Diseases and the Applications in Microbiota

edited by

Alexander Bertuccioli

submission deadline 20 Jul 2025 | 1 articles | Viewed by 2959 | Submission Open

Keywords: microbiota; nutraceuticals; probiotics; prebiotics; postbiotics; IBS; IBD; GERD

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Mechanisms and Treatment Strategies of Myocardial Infarction

edited by Abdul-Majeed Salmasi

submission deadline 20 Jul 2025 | 1 articles | Viewed by 2952 | Submission Open

Keywords: myocardial infarction; genetics; molecular biology; chromosomes; genes; atherosclerosis; coronary artery disease; risk factors

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Editorial Board Members’ Collection Series: QSAR and Computational Approaches to Drug Discovery

edited by

Francisco Torrens

and

Jesús Vicente de Julián-Ortiz

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2924 | Submission Open

Keywords: molecular modelling; molecular simulation; drug design; drug development; molecular mechanism; mathematical chemistry; structure-activity relationship; molecular descriptor; pharmacokinetics; toxicity

(This special issue belongs to the Section Molecular Informatics)

Immunophenotyping in Autoimmune Diseases and Cancer, 4th Edition

edited by

Gabor J. Szebeni

and

Attila Balog

submission deadline 20 Jul 2025 | 1 articles | Viewed by 2903 | Submission Open

Keywords: immunophenotyping; immune regulation; multiparameter cytometry; immuno-oncology; anti-tumor immunity; autoimmunity; cancer immunology; protein– protein interactions; structure/function relationships; sulfur amino acids

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanisms, Pathophysiology and Therapeutic Strategies of Chronic Obstructive Pulmonary Disease (COPD)

edited by

Shih-feng Liu

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2887 | Submission Open

Keywords: chronic obstructive pulmonary disease (COPD); pathophysiology; novel therapeutic approaches; biomarkers; pulmonary rehabilitation; inflammation; oxidative stress; genetic factors

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

cGMP Signaling: From Bench to Bedside

edited by Iraida Sharina

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2879 | Submission Open

Keywords: nitric oxide; cellular signaling; cardiovascular biology; cerebrovascular regulation; aging

(This special issue belongs to the Section Molecular Biology)

Advances in Metalloproteinase

edited by

Kyu-Yeon Han

submission deadline 20 Jul 2025 | 3 articles | Viewed by 2810 | Submission Open

Keywords: matrix metalloproteinases (MMPs); substrate specificity; pathological condition; metalloproteinases inhibitors

(This special issue belongs to the Section Macromolecules)

Neurological Diseases: From Molecular Basis to Therapy

edited by

Claudia Ricci

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2809 | Submission Open

Keywords: neurological diseases; pathogenesis; therapy; personalized medicine; early diagnosis; genetics; neurology; pharmacology

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Stem Cell-Based Regenerative Medicine for Renal Disorders

edited by In-Yong Kim

submission deadline 20 Jul 2025 | 1 articles | Viewed by 2797 | Submission Open

Keywords: chronic kidney disease; acute kidney injury; stem cells; regenerative medicine; stem cell therapy; cellular reprogramming; cell transplantation

(This special issue belongs to the Section Molecular Biology)

Proteomics: An Invaluable Tool to Gain Information on Biological Systems and Their Disease Alterations

edited by

Paolo Iadarola

submission deadline 20 Jul 2025 | 3 articles | Viewed by 2793 | Submission Open

Keywords: high-performance liquid chromatography; two-dimensional electrophoresis; mass spectrometry; biomarker discovery; bioinformatic analysis; biological systems; human fluids; post-translational modifications; protein– protein interaction

(This special issue belongs to the Section Molecular Informatics)

Signalling Pathway and Regulation of Oxidative Stress in Lung Diseases

edited by

Maria Ferraro

and

Elisabetta Pace

submission deadline 20 Jul 2025 | 1 articles | Viewed by 2771 | Submission Open

Keywords: oxidative stress; lung disease; airway epithelium; steroid resistance; antioxidant treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Aspects of Forensic Toxicology

edited by

Angelo Montana

submission deadline 20 Jul 2025 | 1 articles | Viewed by 2732 | Submission Open

Keywords: forensic toxicology; molecular mechanism; toxicological biomarkers; post-mortem interval; in vitro; in vivo; and in silico models; new psychoactive substances (NPSs); new synthetic opioids; liquid chromatography-high resolution mass spectrometry (LC-HRMS/MS); liquid chromatography-tandem mass spectrometry (LC-MS/MS) and gas chromatography-tandem mass spectrometry (GC-MS/MS)

(This special issue belongs to the Section Molecular Toxicology)

Protein Folding, Misfolding, and Related Diseases

edited by

Ludmilla Morozova-Roche

submission deadline 20 Jul 2025 | 1 articles | Viewed by 2730 | Submission Open

Keywords: protein folding; misfolding; amyloid; neurodegenerative diseases; chaperons; mechanisms; regulation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Bone Development and Differentiation in Health and Disease

edited by

Cristina Sánchez-De-Diego

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2720 | Submission Open

Keywords: bone differentiation; signaling pathways; bone diseases; bone formation; osteoblast; osteocyte; osteoclast

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Future Perspectives and Challenges: Interleukins in Immune Diseases

edited by

Yuji Takeda

submission deadline 20 Jul 2025 | 1 articles | Viewed by 2714 | Submission Open

Keywords: immune disease; interleukin; cytokine

(This special issue belongs to the Section Molecular Immunology)

Molecular Research of Cancer Metabolism and Biomarkers

edited by

Mario Cioce

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2657 | Submission Open

Keywords: metabolic reprogramming; tumor microenvironment (TME); resistance; metabolic modulator; multidisciplinary omics approach; cancer metabolism; biomarkers; cancer stem cells

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Fish Genomics and Developmental Biology, 2nd Edition

edited by

Elena Sarropoulou

and

Jorge Fernandes

submission deadline 20 Jul 2025 | 3 articles | Viewed by 2655 | Submission Open

Keywords: development; teleost; gene regulation; comparative genomics; genomics; aquaculture; transcriptomics; gene expression; environment; genomes; population genomics; selective breeding; biomarker

(This special issue belongs to the Section Molecular Biology)

Molecular Research in Parkinson's Disease

edited by

Yi-Chuan Cheng

submission deadline 20 Jul 2025 | 1 articles | Viewed by 2644 | Submission Open

Keywords: Parkinson's disease; molecular regulation; genetic mutations; epigenetics; protein aggregation; mitochondrial dysfunction; neuroinflammation; biomarkers

(This special issue belongs to the Section Molecular Neurobiology)

Bio-Nanopesticides

edited by

Sónia Carabineiro

submission deadline 20 Jul 2025 | 1 articles | Viewed by 2601 | Submission Open

Keywords: bio-nanopesticides; sustainable agriculture; pest control; plant protection; nanotechnology; eco-friendly solutions; environmental impact; toxicity

(This special issue belongs to the Section Molecular Nanoscience)

From Kidney Disease to Hypertension: Molecular Basis and Pathophysiology

edited by

Alexis A. Gonzalez

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2584 | Submission Open

Keywords: renin-angiotensin-aldosterone system; endothelial cell dysfunction; systemic inflammation; hypertension; oxidative stress; vascular remodeling

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 251-300 on page 6 of 70.

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