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International Journal of Molecular Sciences runs special issues to create collections of papers on specific topics. The aim is to build a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors who are experts in the subject and oversee the editorial process for papers. Papers published in a Special Issue will be collected together on a dedicated page of the journal website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Metal-Based Drugs and Research on Mechanisms of Action submission deadline 5 Jun 2023 | 2 articles | Viewed by 1400 | Submission Open
Keywords: transition metals; metal complexes; metallodrugs; drug development; synthesis; imaging agents; structure– activity ratio
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Research in Neuro-Urology
edited by
submission deadline 10 Jun 2023 | 11 articles | Viewed by 9209 | Submission Open
Keywords: Neuro-urology; Neurogenic lower urinary tract dysfunction; Neurogenic sexual dysfunction; Neurogenic bowel dysfunction; Neurological disorders; Pathomechanisms; Molecular level
(This special issue belongs to the Section Molecular Neurobiology)
Infrared and Raman Spectroscopy of Human Diseases submission deadline 10 Jun 2023 | 6 articles | Viewed by 7904 | Submission Open
Keywords: Infrared spectroscopy; Raman spectroscopy; Biological molecules; Diseases; Orthopaedics; Medicine; Diagnosis
(This special issue belongs to the Section Molecular Biophysics)
UV-B Signaling and Its Molecular Control in Plant
edited by Shaoshan Li
submission deadline 10 Jun 2023 | 5 articles | Viewed by 5280 | Submission Open
Keywords: UV-B; UVR8 (UV-B photoreceptor); UV-B signaling; photomorphogenesis; COP1; HY5; RUP1/RUP2
(This special issue belongs to the Section Molecular Plant Sciences)
Pesticides Exposure and Toxicity
edited by
submission deadline 10 Jun 2023 | 5 articles | Viewed by 4688 | Submission Open
Keywords: multiple pesticides; cumulative assessment; probabilistic assessment; mechanisms of molecular toxicology
(This special issue belongs to the Section Molecular Toxicology)
Microbial Enzymes for Biotechnological Applications submission deadline 10 Jun 2023 | 3 articles | Viewed by 4556 | Submission Open
(This special issue belongs to the Section Biochemistry)
Dendrimers, Dendrigrafts, and Molecular Brushes: Synthesis, Experimental and Theoretical Studies, and Applications
edited by
submission deadline 10 Jun 2023 | 5 articles | Viewed by 3610 | Submission Open
Keywords: dendrimers; dendrigrafts; molecular brushes; synthesis; theory; simulations; experiments; applications
(This special issue belongs to the Section Macromolecules)
DNA/Polymer-Mediated Assembly of Nanoparticles submission deadline 10 Jun 2023 | 1 articles | Viewed by 1095 | Submission Open
Keywords: nanoparticle; self-assembly; polymer-mediated; DNA-mediated; nanomedicine; material science; biomaterial; micelle; conjugate
(This special issue belongs to the Section Macromolecules)
The Role of Pharmacogenetic and Pharmacogenomic on the Influence of Drug Response submission deadline 10 Jun 2023 | 1 articles | Viewed by 1089 | Submission Open
Keywords: pharmacogenetics; pharmacogenomic; drug response; ADR; efficacy  
(This special issue belongs to the Section Molecular Pharmacology)
Novel Natural Compound for Wound and Tissue Repair and Regeneration submission deadline 15 Jun 2023 | 14 articles | Viewed by 14271 | Submission Open
Keywords: wound repair; tissue regeneration; natural compounds; phytochemicals; molecular mechanisms
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Inflammatory Bowel Disease: From Pre-clinial Models into Translation
edited by
submission deadline 15 Jun 2023 | 4 articles | Viewed by 11340 | Submission Open
(This special issue belongs to the Section Molecular Immunology)
Tackling New and Reemerging Infectious Diseases through the Development of Novel Anti-infectives submission deadline 15 Jun 2023 | 4 articles | Viewed by 10422 | Submission Open
Keywords: antivirals; antibacterials; virus; CoViD-19; pathogenic bacteria; antibiotic resistance; antifungals; anthelmintics; antimalarials; antiprotozoals
(This special issue belongs to the Section Biochemistry)
Molecular Regulation and Mechanism of Ribonucleoprotein Complexes submission deadline 15 Jun 2023 | 10 articles | Viewed by 10375 | Submission Open
Keywords: ribonucleoprotein  сomplexes (RNP); RNA viruses; vault complex; ribosome; spliceosome; heterogeneous ribonucleoprotein particles (hnRNP); telomerase; replicase; RNase P; aminoacyl-tRNA synthetases
(This special issue belongs to the Section Molecular Biology)
Neuroinflammation: From Molecular Basis to Therapy
edited by
submission deadline 15 Jun 2023 | 6 articles | Viewed by 10122 | Submission Open
Keywords: neuroinflammation; CNS disorders; neurodegenerative disorders; Parkinson’ s disease (PD); Alzheimer’ s disease (AD); Huntington’ s disease (HD); frontotemporal dementia (FTD); amyotrophic lateral sclerosis (ALS); infections; HIV; SARS-CoV-2; genetics
(This special issue belongs to the Section Molecular Neurobiology)
Environmental Determinants and Their Impact on Human Reproduction and Reproductive Immunology
edited by Gulfam Ahmad and
submission deadline 15 Jun 2023 | 7 articles | Viewed by 9726 | Submission Open
Keywords: environment; reproduction; endocrine; infertility; determinants; molecular; mechanisms
(This special issue belongs to the Section Molecular Immunology)
Neurogenesis and Neural Plasticity 2.0
edited by and
submission deadline 15 Jun 2023 | 5 articles | Viewed by 9421 | Submission Open
Keywords: neural stem cells; neural regeneration; neurogenesis; synaptogenesis; aging; oxidative stress; paracrine activity; metabolic plasticity; gut– brain axis; secretome
(This special issue belongs to the Section Molecular Neurobiology)
Neural Correlates and Molecular Mechanisms of Memory and Learning submission deadline 15 Jun 2023 | 5 articles | Viewed by 8108 | Submission Open
Keywords: learning; memory; synaptic plasticity; long-term potentiation; hippocampus; amygdala; prefrontal cortex
(This special issue belongs to the Section Molecular Neurobiology)
Macroscopic and Microscopic Thermodynamics: From Fundamentals to Present Applications 2.0 submission deadline 15 Jun 2023 | 10 articles | Viewed by 7770 | Submission Open
Keywords: thermophysical properties; statistical thermodynamics; intermolecular forces; molecular models; applied thermodynamics; phase equilibria; transport across interfaces; process modeling; advanced separation processes
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Trends and Applications in Computationally Driven Drug Repurposing
edited by and
submission deadline 15 Jun 2023 | 5 articles | Viewed by 7704 | Submission Open
Keywords: drug repurposing; target identification; artificial intelligence; machine learning; deep learning; molecular modelling; chemoinformatics; big data; medicinal chemistry
(This special issue belongs to the Section Molecular Informatics)
Aging and Heart Disease submission deadline 15 Jun 2023 | 5 articles | Viewed by 7458 | Submission Open
Keywords: heart disease; aging; geriatrics; frailty; signaling pathways
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Sleep Apnea and Systemic Inflammation submission deadline 15 Jun 2023 | 7 articles | Viewed by 7414 | Submission Open
Keywords: inflammation; monocytes; innate immune response; OSA; immunology
(This special issue belongs to the Section Molecular Immunology)
Modulation of Protein Structure and Function by Lipids submission deadline 15 Jun 2023 | 6 articles | Viewed by 6326 | Submission Open
Keywords: protein modulation by lipids; phosphoinositides; cholesterol; sterols; fatty acids; G protein-coupled receptors; ion channels; transporters
(This special issue belongs to the Section Biochemistry)
Alzheimer’s Disease and Other Dementias-Novel Therapeutic Approaches-3rd Edition submission deadline 15 Jun 2023 | 5 articles | Viewed by 6087 | Submission Open
Keywords: dementia; prevention of dementia; treatment of dementia; amyloid; tangles; tauopathies; mild cognitive impairment; neurodegenerative pathways; toxic elements inducing dementia; drug screening; drug design; cell or organelle therapy; device development; neurodegeneration; neuroinflammation
(This special issue belongs to the Section Molecular Neurobiology)
Reproductive Immunology and Pregnancy 3.0
edited by
submission deadline 15 Jun 2023 | 6 articles | Viewed by 5862 | Submission Open
Keywords: gamete immunology; in vitro fertilization; infertility; immunocontraception; implantation; placentation; immunotolerance; reproductive immunology; inflammation; cytokine network; placenta-derived stem cells; endometriosis; immunopathology of pregnancy; sex hormones
(This special issue belongs to the Section Molecular Immunology)
Carbonaceous Nanomaterials: Design, Preparation and Application submission deadline 15 Jun 2023 | 6 articles | Viewed by 5526 | Submission Open
Keywords: carbon nanomaterials; carbon (nano)fillers; graphene; carbon nanotubes; carbon quantum dots; nanoparticles; nanostructures
(This special issue belongs to the Section Materials Science)
New Anticancer Agents: Design, Synthesis and Evaluation submission deadline 15 Jun 2023 | 5 articles | Viewed by 5327 | Submission Open
Keywords: medicinal chemistry of anticancer drugs; preclinical evaluation; cytotoxic effects; targets for cancer treatment; small molecules for cancer treatment; non-clinical anticancer effects; biochemistry of tumor cells
(This special issue belongs to the Section Molecular Oncology)
Peripheral Biomarkers in Neurodegenerative Diseases 3.0
edited by and
submission deadline 15 Jun 2023 | 5 articles | Viewed by 5081 | Submission Open
Keywords: Alzheimer’ s disease; Parkinson disease; Huntington disease; amyotrophic lateral sclerosis; Friedreich’ s ataxia; Lewy bodies dementia; spinal muscular atrophy
(This special issue belongs to the Section Molecular Neurobiology)
Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases
edited by Joseph E. Deweese and Neil Osheroff
submission deadline 15 Jun 2023 | 5 articles | Viewed by 4900 | Submission Open
Keywords: topoisomerase; DNA supercoiling; DNA topology; anticancer; antimicrobial; DNA damage
(This special issue belongs to the Section Molecular Biology)
Natural Bioactive Compounds against Microorganisms: Sources and Mechanism of Action
edited by
submission deadline 15 Jun 2023 | 3 articles | Viewed by 4530 | Submission Open
Keywords: natural compounds; phytoextracts; mechanism of action; anti-infective activity; experimental tests; computational studies; atomistic machinery
(This special issue belongs to the Section Molecular Microbiology)
Development and Application of Carbon Nanomaterials Used in Human and Animal Healthcare submission deadline 15 Jun 2023 | 5 articles | Viewed by 4491 | Submission Open
Keywords: carbon nanomaterials; carbon quantum dots; carbon nanogels; biosensors; therapeutical agents; nanotoxicity
(This special issue belongs to the Section Molecular Nanoscience)
Supramolecular Chemistry on Metal Nanoparticles
edited by
submission deadline 15 Jun 2023 | 4 articles | Viewed by 4124 | Submission Open
Keywords: assembly; host-guest chemistry; quantum confinement effects; nanostructure; gold nanoparticles; silver nanoparticles; noble metals; signaling; non-covalent bonds; surface chemistry; colloid chemistry
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Genetics in Bone Diseases
edited by
submission deadline 15 Jun 2023 | 4 articles | Viewed by 4086 | Submission Open
Keywords: odontoblast; osteoblast; Gorlin syndrome; bone regeneration; genes in bone tissue; bone tissue development; bone disease
(This special issue belongs to the Section Molecular Genetics and Genomics)
Dental Implants Biomaterials submission deadline 15 Jun 2023 | 4 articles | Viewed by 4073 | Submission Open
Keywords: implant titanium surface; bone graft; bone substitutes; biomedical applications; bone regeneration; ceramic implants; titanium implants; biomechanical behaviour of dental implants
(This special issue belongs to the Section Materials Science)
The Role of Estrogen and Its Receptors in the Development and Therapy of Cancer submission deadline 15 Jun 2023 | 5 articles | Viewed by 4011 | Submission Open
Keywords: estrogen; estrogen receptor; breast cancer; anticancer therapy; cancer development; cancer progression; metastasis
(This special issue belongs to the Section Molecular Oncology)
Current Advances in Metal Complexes with Biological Activity submission deadline 15 Jun 2023 | 4 articles | Viewed by 3816 | Submission Open
Keywords: metal-based drugs; drug discovery; anticancer activity; antibacterial activity; transition metal complexes
(This special issue belongs to the Section Molecular Pharmacology)
Oral Squamous Cell Carcinoma—Pathogenetic, Diagnostic and Therapeutic Perspectives submission deadline 15 Jun 2023 | 4 articles | Viewed by 3724 | Submission Open
Keywords: oral squamous cell carcinoma; molecular biology; pathology; microbiome; biomarkers; genetic alterations; biological behavior; diagnostics and therapeutics; reconstructive therapy; chemoresistance; radioresistantce
(This special issue belongs to the Section Molecular Oncology)
Synaptic Vulnerability: From Biological to Therapeutic Point of View
edited by and
submission deadline 15 Jun 2023 | 3 articles | Viewed by 3421 | Submission Open
Keywords: synaptic vesicles; vesicle turnover; neurotransmitter release; excitability; neurodegeneration; mitochondrial deficit; synaptic homeostasis; cognitive deficit; Parkinson’ s disease; Alzheimer’ s disease; epilepsy
(This special issue belongs to the Section Molecular Neurobiology)
Cardiovascular Pharmacology and Interventions: Future Directions for Cardioprotection 2.0
edited by
submission deadline 15 Jun 2023 | 4 articles | Viewed by 3307 | Submission Open
Keywords: cardiovascular pharmacology; coronary circulation; myocardial ischemia and infarction; heart failure
(This special issue belongs to the Section Molecular Pharmacology)
Vibrational Spectroscopy Methods to Investigate Macromolecules
edited by
submission deadline 15 Jun 2023 | 3 articles | Viewed by 2791 | Submission Open
Keywords: FTIR; Raman; resonant Raman; SERS; DNA; proteins; polymers; green chemistry
(This special issue belongs to the Section Macromolecules)
Advances in Lung Injury, Regeneration, and Fibrosis
edited by
submission deadline 15 Jun 2023 | 3 articles | Viewed by 2656 | Submission Open
Keywords: idiopathic pulmonary fibrosis; myofibroblast; extracellular matrix; infections; acute respiratory distress syndrome
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cellular and Molecular Mechanisms of Heart Development: Implications for Heart Disease and Regeneration
edited by
submission deadline 15 Jun 2023 | 2 articles | Viewed by 2405 | Submission Open
(This special issue belongs to the Section Molecular Biology)
Micro and Nanosystems for Drug Delivery submission deadline 15 Jun 2023 | 1 articles | Viewed by 2088 | Submission Open
Keywords: microparticles; nanoparticles; biopharmaceuticals; drug delivery; drug targeting; absorption; particle internalization; endocytosis; mucoadhesion
(This special issue belongs to the Section Molecular Pharmacology)
Chronic Inflammatory Lung Diseases: Molecular Pathology
edited by and
submission deadline 15 Jun 2023 | 2 articles | Viewed by 2068 | Submission Open
Keywords: asthma; COPD; lung fibrosis; tissue remodeling; tissue degradation; cell-cell interaction; chronic inflammation lung diseases; cellular signaling; cell differentiation; cell aging; cell metabolism; mitochondrial action; cellular sugars; extracellular matrix
(This special issue belongs to the Section Molecular Immunology)
Nanoparticles: From Synthesis to Applications 2.0
edited by
submission deadline 15 Jun 2023 | 2 articles | Viewed by 1995 | Submission Open
Keywords: nanotechnology; nanocrystals; colloidal nanoparticles; synthesis of nanoparticles; nanostructures; spectroscopy; surface functionalization; diagnosis; sensors; theranostics; biomedical applications; drug delivery; control release; biocompatibility
(This special issue belongs to the Section Materials Science)
Advantage Application of Coordination Complexes in Bio-Chemical Processes
edited by and
submission deadline 15 Jun 2023 | 2 articles | Viewed by 1801 | Submission Open
Keywords: coordination complex; chemical biology; inorganic Chemistry; biomedical applications; bio-chemical processes
(This special issue belongs to the Section Biochemistry)
Advances in Luminescent Materials: Design and Functionalizations submission deadline 15 Jun 2023 | 2 articles | Viewed by 1793 | Submission Open
Keywords: luminescence; photochromic materials; thermochromic materials; OLED; MOF sensors; biomarkers; lanthanide luminescence; 3d-metal’ s complexes luminescence
(This special issue belongs to the Section Materials Science)
Emerging Challenges in the Diagnosis and Treatment of Alzheimer’s Disease: The Role of Neuroinflammation and Microglia Biomarkers
edited by
submission deadline 15 Jun 2023 | 2 articles | Viewed by 1266 | Submission Open
Keywords: Alzheimer’ s Disease; neurofibrillary tangles; CX3CL1; microglia; neuroinflammation; neuro-immune cross-talk; neurodegeneration
(This special issue belongs to the Section Molecular Neurobiology)
Overcoming Brain Barriers submission deadline 15 Jun 2023 | 1 articles | Viewed by 1258 | Submission Open
Keywords: choroid plexus; blood– cerebrospinal fluid barrier; blood– brain barrier; brain disorders; drug delivery
(This special issue belongs to the Section Biochemistry)
Lipid Molecules in Inflammation and Chronic Diseases 2.0
edited by
submission deadline 15 Jun 2023 | 1 articles | Viewed by 1219 | Submission Open
Keywords: lipid signaling; lipid metabolism; inflammatory; pathways; lifestyle-related diseases
(This special issue belongs to the Section Molecular Immunology)
Molecular Immunology of Solid Tumors 2.0
edited by
submission deadline 15 Jun 2023 | 1 articles | Viewed by 1117 | Submission Open
Keywords: immune; solid tumors; anti-tumor; molecular pathways
(This special issue belongs to the Section Molecular Immunology)
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