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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Vitamins and Derived Cofactors: Transport, Metabolism, Assembly and Deficiencies

edited by

Maria Barile

and

Michele Galluccio

submission deadline 25 Jul 2024 | 7 articles | Viewed by 10830 | Submission Open

Keywords: vitamin; cofactor; transporter; assembly; vitamin-responsive inborn errors of metabolism

(This special issue belongs to the Section Biochemistry)

C. elegans as a Disease Model: Molecular Perspectives

edited by

Krisztina Takács-Vellai

submission deadline 25 Jul 2024 | 6 articles | Viewed by 8445 | Submission Open

Keywords: Caenorhabditis elegans; model organism; disease model; neurodegenerative diseases; cancer model; ageing

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Neuromodulatory Effects of Serotonin

edited by

Yasemin M. Akay

submission deadline 25 Jul 2024 | 7 articles | Viewed by 8159 | Submission Open

Keywords: neuromodulation; Serotonin; pain research; cognition; emotions; depression; anxiety; GBM

(This special issue belongs to the Section Molecular Neurobiology)

Recent Advances in the Diagnosis and Treatment of Chronic Liver Diseases 2023

edited by

Hirayuki Enomoto

submission deadline 25 Jul 2024 | 6 articles | Viewed by 7508 | Submission Open

Keywords: biomarker; genomic research; epigenomic research; molecular mechanisms; viral hepatitis; alcoholic-related liver disease; non-alcoholic fatty liver disease; autoimmune liver diseases; liver cirrhosis; hepatocellular carcinoma

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Research of Skin Inflammation and Related Diseases

edited by

Filomena Napolitano

and

Valentina Giudice

submission deadline 25 Jul 2024 | 5 articles | Viewed by 7343 | Submission Open

Keywords: skin; inflammation; molecular target; inflammatory skin diseases; psoriasis; urticaria; atopic dermatitis; systemic sclerosis; skin fibrosis; immune system

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Platelet Activation in Human Health and Disease

edited by Demokritos Tsoukatos

submission deadline 25 Jul 2024 | 6 articles | Viewed by 7320 | Submission Open

Keywords: integrin α Ι Ι bβ 3; α IIb subunit; platelet aggregation; platelet activation; talin; peptide inhibitors

(This special issue belongs to the Section Molecular Immunology)

Endothelial Dysfunction and Cardiovascular Diseases

edited by

Olga Kruszelnicka

submission deadline 25 Jul 2024 | 3 articles | Viewed by 3914 | Submission Open

Keywords: chemokines; cytokines; leukocyte trafficking; leukocyte attracting; leukocyte-derived cytokines; nitric oxide; prostacyclin; adhesion molecules; endothelium

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Signaling Pathways in Acute and Chronic Inflammation

edited by

Rosanna Di Paola

submission deadline 25 Jul 2024 | 2 articles | Viewed by 3757 | Submission Open

Keywords: pathways; biomarker; biochemistry; oxidative stress; tissue injury

(This special issue belongs to the Section Molecular Biology)

Bioactive Agents Effective in the Prevention of Metabolic Syndrome

edited by Luís R. Silva

submission deadline 25 Jul 2024 | 1 articles | Viewed by 3344 | Submission Open

Keywords: metabolic syndrome; bioactive compounds; cardiovascular disease; diabetes mellitus; inflammation; functional foods; obesity

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Functions and Applications of Natural Products

edited by Seung-Hong Lee and

Seon-Heui Cha

submission deadline 25 Jul 2024 | 3 articles | Viewed by 2912 | Submission Open

Keywords: natural products; biomedicine/phytomedicine; biologically active extracts and compounds; pharmacological and toxicological mechanisms of action

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Therapeutic Potential of Natural Compounds: Insights into Mechanisms, Molecular Docking, and Biological Activities

edited by

Rafał Hałasa

submission deadline 25 Jul 2024 | 2 articles | Viewed by 2873 | Submission Open

Keywords: natural compounds; synthetic derivatives of natural compounds; biological activity; mechanism of action; molecular docking; therapeutic potential; anticancer; antimicrobial; antiviral; anti-civilization diseases; antiobesity; antidiabetes; preventing the development of cardiovascular diseases; including myocardial infarction; hypertension and ischemic heart disease; food hypersensitivity; antiallergy

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Natural Products and Oral Health: Challenges and Opportunities

edited by

Francisca Rodrigues

and

Paulo Cardoso Da Costa

submission deadline 25 Jul 2024 | 1 articles | Viewed by 1083 | Submission Open

Keywords: phytochemicals; natural compounds ; antitumor activity; oral mucositis; encapsulation ; drug delivery systems ; oxidative stress; metabolic pathways ; protein expression; cellular signaling ; cancer prevention ; immunomodulation ; adjuvant therapy; preventive therapy

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Recent Advances in Maize Stress Biology

edited by

Haidong Lu

submission deadline 25 Jul 2024 | 1 articles | Viewed by 962 | Submission Open

Keywords: maize; crop stress resistance; molecular biology; stress resistance genes; yield

(This special issue belongs to the Section Molecular Plant Sciences)

Current Insights into Nucleic Acids

edited by

David Stephen Pisetsky

submission deadline 25 Jul 2024 | 1 articles | Viewed by 897 | Submission Open

Keywords: nucleic acids; DNA; RNA; genome; gene function; gene regulation; gene structure

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advances in Immunology and Inflammation during and after Infectious Diseases

edited by

Manuela Ceccarelli

submission deadline 25 Jul 2024 | 1 articles | Viewed by 885 | Submission Open

Keywords: bacterial infections; fungi infections; HIV; COVID-19; immune response; inflammation

(This special issue belongs to the Section Molecular Immunology)

Molecular Research of Epithelial Function and Barrier Dysfunction

edited by Fariba Rezaee

submission deadline 25 Jul 2024 | 1 articles | Viewed by 660 | Submission Open

Keywords: epithelial cells; actin cytoskeleton; viral infection; apical junctional complex; tight junction; adherens junction; barrier dysfunction; trans-epithelial electrical resistance; permeability; epithelial barrier

(This special issue belongs to the Section Molecular Immunology)

Antimicrobial, Anti-biofilm and Anti-virulence Activities of Novel Compounds

edited by

Mara Di Giulio

and

Silvia Di Lodovico

submission deadline 25 Jul 2024 | Viewed by 453 | Submission Open

Keywords: antimicrobial natural compound; resistant strains; mono- and polymicrobial biofilm; synergisms; antivirulence natural compounds

(This special issue belongs to the Section Molecular Microbiology)

Vaccine Research and Adjuvant Discovery

edited by Kendal Ryter

submission deadline 25 Jul 2024 | Viewed by 345 | Submission Open

Keywords: C-type lectin receptor; mincle; toll-like receptor

(This special issue belongs to the Section Molecular Immunology)

Gastrointestinal Disorder and Cancer: Biochemical and Molecular Insight

edited by Faisal Aziz

submission deadline 25 Jul 2024 | Viewed by 326 | Submission Open

(This special issue belongs to the Section Molecular Oncology)

Integrative Multi-Omics Analysis for Cancer Biomarkers

edited by

Youping Deng

and

Kurt K. Zhang

submission deadline 25 Jul 2024 | Viewed by 324 | Submission Open

Keywords: bioinformatics; biomedical informatics; cancer; genomics; systems biology

(This special issue belongs to the Section Molecular Oncology)

Targeted Therapy and Molecular Strategies for Gynecological Cancer

edited by

Matin Sheriff

and

Stergios Boussios

submission deadline 25 Jul 2024 | Viewed by 317 | Submission Open

Keywords: gynecological cancer; targeted therapy; molecular markers; genomic profiling; immunotherapy; personalized medicine; multidisciplinary approach

(This special issue belongs to the Section Molecular Oncology)

Latest Updates about Interstitial Lung Disease

edited by

Katarzyna B. Lewandowska

and

Monika Szturmowicz

submission deadline 25 Jul 2024 | Viewed by 282 | Submission Open

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Biology on Cancer Genomics, Precision Medicine and Public Health

edited by

Rui Medeiros

submission deadline 25 Jul 2024 | Viewed by 247 | Submission Open

Keywords: liquid biopsy; cancer genomics; epigenetics; tumor microenvironment; regulation of immunity; tumor cell signaling; targeted therapy; drugs for cancer; precision medicine

(This special issue belongs to the Section Molecular Oncology)

Research on Advanced Bioanalytical Approaches for Biomolecules Detection

edited by

Almira Ramanaviciene

Anton Popov

and

Asta Kausaite-Minkstimiene

submission deadline 25 Jul 2024 | Viewed by 242 | Submission Open

Keywords: biosensors; immunosensors; immuno- or bio-assay; molecularly imprinted polymers; nanoparticles; biomarkers; analytical signal amplification strategies

(This special issue belongs to the Section Molecular Informatics)

Lung Transplantation and Lung Diseases: Molecular Pathogenesis and Advanced Therapies

edited by Christopher Lambers

submission deadline 25 Jul 2024 | Viewed by 242 | Submission Open

Keywords: lung disease; lung transplantation; ECMO; EVLP; LAS; antibody-mediated rejection (AMR); CLAD; RAS/BOS; immunosuppression; pathogenesis; cell-free DNA; IPF therapies; gene therapies; stem cell therapies; immunotherapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Metabolic Alterations in Muscle Diseases and Cancer Cachexia

edited by

Tania Fiaschi

submission deadline 25 Jul 2024 | Viewed by 230 | Submission Open

Keywords: skeletal muscle; cancer cachexia; metabolism; regulatory RNAs; epigenetic modifications; signal transduction

(This special issue belongs to the Section Molecular Biology)

Microbial Metabolism and Enzymology: Insights into the Degradation of Organic Substrates by Environmental Bacteria

edited by

Elias R. Olivera

submission deadline 25 Jul 2024 | Viewed by 212 | Submission Open

Keywords: bacterial biodegradation; metabolism; enzymes; genomics; metabolomics; xenobiotics; aromatic compounds; alkanes; steroids; pollutants

(This special issue belongs to the Section Molecular Microbiology)

Advanced Research on CAR-T Cell Therapy

edited by

Yasushi Akahori

submission deadline 25 Jul 2024 | Viewed by 202 | Submission Open

Keywords: CAR T cell therapy; T cell activation; memory lymphocyte differentiation; cancer vaccine; antigen spread

(This special issue belongs to the Section Molecular Immunology)

Plant Oxidative Metabolism and Dynamic Balance of Polyamines

edited by

Ágnes Szepesi

submission deadline 25 Jul 2024 | Viewed by 172 | Submission Open

Keywords: polyamines; oxidative metabolism; vertical farming; sustainable agriculture; root system architecture; urban farming; space farming

(This special issue belongs to the Section Molecular Plant Sciences)

Targeting Epigenetics in Cancer Therapy

edited by Tamer E. Fandy

submission deadline 25 Jul 2024 | Viewed by 151 | Submission Open

Keywords: epigenetic therapy; histone acetylation; histone modifications; DNA methylation; DNA methyltransferase inhibitors; histone deacetylase inhibitors; histone methylation; miRNA modifications; herbal products

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanism and Treatment of Hemangioma

edited by Jaesung P. Choi

submission deadline 25 Jul 2024 | Viewed by 146 | Submission Open

Keywords: hemangioma; angioma; cavernoma; vascular diseases; benign tumor; small vessels

(This special issue belongs to the Section Molecular Oncology)

Controlled Free-Radical Polymerization: Recent Developments and Industrial Applications

edited by

Dario Pasini

submission deadline 25 Jul 2024 | Viewed by 93 | Submission Open

Keywords: conventional free radical polymerization (FRP); vinyl monomers; controlled/living radical polymerization (CRP)

(This special issue belongs to the Section Macromolecules)

Advances in Skin Cancer Pathology: From Pathogenesis to Precision Therapies

edited by

Ovidiu Simion Cotoi

submission deadline 26 Jul 2024 | 3 articles | Viewed by 4673 | Submission Open

Keywords: skin cancer; melanoma; non-melanoma; immunotherapy; cutaneous malignancies; targeted therapy; early detection

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Neurodegenerative Diseases and Inflammation: Pathogenesis, Biomarkers and Treatments

edited by

Luisa Agnello

and Anna Maria Ciaccio

submission deadline 26 Jul 2024 | 1 articles | Viewed by 2076 | Submission Open

Keywords: neurodegeneration; inflammation; biomarkers; Alzheimer’ s disease; molecular mechanism; pathogenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Activation, Proliferation and Migration of Endothelial Cells under Normal and Pathological Conditions

edited by

Alexandre Mironov

submission deadline 26 Jul 2024 | 3 articles | Viewed by 2052 | Submission Open

Keywords: endothelial cell; regeneration; angiogenesis; migration; molecular mechanism; intracellular transport; Golgi; signaling; transcription; miRNA; tumorigenesis; COVID

(This special issue belongs to the Section Molecular Biology)

Editorial Board Members’ Collection Series: "Exploring Molecular Mechanisms in Cancer Biology"

edited by

Chiara Laezza

and

Benoît Chénais

submission deadline 26 Jul 2024 | 1 articles | Viewed by 1495 | Submission Open

Keywords: angiogenesis; cancer biomarkers; cancer therapy; epigenetics; genetics; immune response; metabolism; metastasis; mutation; resistance; tumor microenvironment

(This special issue belongs to the Section Molecular Biology)

Molecular Research in Pregnancy, Childbirth, and Related Complications

edited by

Nicoletta Di Simone

submission deadline 26 Jul 2024 | 1 articles | Viewed by 946 | Submission Open

Keywords: pregnancy complications ; preeclampsia ; gestational hypertension ; HELLP syndrome ; gestational diabetes ; preterm labor; fetal growth restriction ; placenta previa ; recurrent pregnancy loss ; stillbirth

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Diagnostics and Therapeutics of Epileptic Neurodevelopment

edited by Christalena Sofocleous

submission deadline 28 Jul 2024 | 2 articles | Viewed by 3025 | Submission Open

Keywords: epileptic neurodevelopment; molecular diagnostics; next-generation sequencing; genetics; epigenetics; pathogenic/likely pathogenic variants; therapeutics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Secondary Metabolites and Their Synthetic Derivatives as Potential Plant Protection Products

edited by

Natale Badalamenti

submission deadline 28 Jul 2024 | 1 articles | Viewed by 1164 | Submission Open

Keywords: terpenoids; biological activities; natural products; NMR; synthetic derivatives; structural modification; mechanism of action

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Red Blood Cell Hemodynamic Functionality in Health and Disease

edited by Saul Yedgar and

Gregory Barshtein

submission deadline 28 Jul 2024 | Viewed by 182 | Submission Open

Keywords: red blood cells; RBC flow-affecting properties; RBC deformability; RBC aggregation; RBC adherence; RBC fragility; blood circulation disorders; blood transfusion

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Nanomaterials in Nanobiotechnology and Nanomedicine 2.0

edited by

Han-Jia Lin

and

Chih-Ching Huang

submission deadline 28 Jul 2024 | Viewed by 153 | Submission Open

Keywords: nanomaterials; nanotoxicity; nanogels; carbon-based nanomaterials; metal-based nanomaterials; nanocomposites; fullerenes; nanoparticles; biosensors; therapeutical agents; DNA damage; DNA stability; nano-drug delivery system; antibacterial; antiviral; antioxidant; anti-inflammation; antitumor/anticancer

(This special issue belongs to the Section Molecular Nanoscience)

Acute Respiratory Distress Syndrome (ARDS): New Insights into the Mechanisms and Emerging Therapies

edited by

Youyang Zhao

submission deadline 28 Jul 2024 | Viewed by 133 | Submission Open

Keywords: acute lung injury; ARDS; endothelial barrier; epithelial barrier; acute inflammation; repair; regeneration; resolution of inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Microbiome and Skin and Mucocutaneous Diseases

edited by

Liborija Lugovic-Mihic

submission deadline 29 Jul 2024 | 2 articles | Viewed by 5065 | Submission Open

Keywords: microbiome; skin; microorganisms; inflammation; skin diseases; healthy skin; probiotics; mucocutaneous diseases

(This special issue belongs to the Section Molecular Microbiology)

Latest Progress in DNA Damage and DNA Repair

edited by

Mahara Valverde

and Emilio Rojas

submission deadline 29 Jul 2024 | 2 articles | Viewed by 2849 | Submission Open

Keywords: DNA damage; DNA repair mechanisms; DNA damage response (DDR); post-translational regulation; chemoresistance; cell diferentiation; disease

(This special issue belongs to the Section Molecular Genetics and Genomics)

The Microbiota and Its Association with Cellular Transformation and Metabolic Changes, 2nd Edition

edited by

Davide Zella

and

Francesca Benedetti

submission deadline 29 Jul 2024 | 2 articles | Viewed by 2770 | Submission Open

Keywords:

(This special issue belongs to the Section Molecular Microbiology)

Advanced Synthetic Methodologies in Drug Development

edited by

Davide Moi

submission deadline 29 Jul 2024 | 1 articles | Viewed by 1948 | Submission Open

Keywords: organic chemistry; medicinal chemistry; catalysis; photo-catalysis; green chemistry; drug design; drug analysis; flow chemistry

(This special issue belongs to the Section Molecular Pharmacology)

New Insights into Liver Biology and Disease Pathogenesis: Shedding Light on Novel Diagnostic and Therapeutic Approaches

edited by

Thiago Almeida Pereira

submission deadline 29 Jul 2024 | 2 articles | Viewed by 1466 | Submission Open

Keywords: liver molecular biology; novel biomarkers; liver regeneration; liver repair; liver carcinogenesis; brain– gut– liver axis; novel therapeutic targets; molecular diagnostic tools; host– pathogen interactions; novel in vitro and in vivo models of liver diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Insights and Applications from Plant Stem Cell Research

edited by

Ján Kraic

submission deadline 29 Jul 2024 | Viewed by 444 | Submission Open

Keywords: stem cell; stem cell-like cell; meristems; callus cultures; cell suspension cultures; in vitro production

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Bioinformatics in Pediatric Diseases

edited by

Giovanni Fiorito

submission deadline 29 Jul 2024 | Viewed by 138 | Submission Open

Keywords: pediatric diseases; bioinformatics; in utero and early-life exposures; multi-omic biomarkers; personalized medicine

(This special issue belongs to the Section Molecular Informatics)

Biomechanics and Molecular Research on Glioblastoma

edited by

Lorenzo Corsi

submission deadline 30 Jul 2024 | 10 articles | Viewed by 25594 | Submission Open

Keywords: GBM; molecular pathways; biomechanics; oncogene; cancer; microenvironment; drug targeting; diagnostic; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

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