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International Journal of Molecular Sciences runs special issues to create collections of papers on specific topics. The aim is to build a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors who are experts in the subject and oversee the editorial process for papers. Papers published in a Special Issue will be collected together on a dedicated page of the journal website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Prospective and Cutting-Edge Research for Diabetic Complications
edited by Daiji Kawanami
submission deadline 25 May 2022 | 2 articles | Viewed by 2001
Keywords: diabetic complications; diabetic retinopathy; diabetic kidney disease; diabetic macroangiopathy; bone metabolism in diabetes; hormones in diabetes; dementia; sarcopenia; frail; biomarkers; molecular biology
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Cytokine Release Syndrome: From Cell Metabolism to Organ Dysfunction
edited by
submission deadline 26 May 2022 | 1 articles | Viewed by 1636
Keywords: cytokine storm; cytokine release syndrome; CRS; immune-related adverse event; immunotherapy; COVID-19; SARS-CoV-2
(This special issue belongs to the Section Molecular Immunology)
Updates of Calcineurin/NFAT Signaling in Human Health and Diseases
edited by
submission deadline 26 May 2022 | 3 articles | Viewed by 3636
Keywords: allergy; bone metabolism; calcineurin; cancer; cell cycle; immunosuppressant; osmolarity; reproduction; NFAT
(This special issue belongs to the Section Molecular Immunology)
Skeletal Muscle Molecular Signalling in Various Models of Disuse and Unloading
edited by and Carlo Reggiani
submission deadline 27 May 2022 | 5 articles | Viewed by 3874
Keywords: skeletal muscle; disuse; unloading; inactivity; muscle atrophy; muscle atonia; slow-to-fast myosin transition; mitochondrial impairment; intracellular and intercellular signal transduction pathways; proteostasis; cytoskeleton; gene expression
(This special issue belongs to the Section Molecular Biophysics)
Emerging Therapies for Malignant Mesothelioma
edited by and Magkouta Sophia
submission deadline 27 May 2022 | 2 articles | Viewed by 1309
Keywords: pleural mesothelioma; immunotherapy; combination therapy; clinical trial; preclinical studies; pleural fluid; tumor microenvironment; adjuvant therapy; radiation therapy; cancer vaccines; nanotechnology; biomarkers
(This special issue belongs to the Section Molecular Oncology)
Plant Genetic Diversity and Genomics
edited by and
submission deadline 27 May 2022 | 3 articles | Viewed by 2286
Keywords: plant genetic diversity; speciation; phylogeography; evolutionary genetics; phylogenomics
(This special issue belongs to the Section Molecular Plant Sciences)
Amniotic Fluid and Placental Membranes as Sources of Stem Cells 2.0
edited by Tullia Maraldi and
submission deadline 27 May 2022 | 2 articles | Viewed by 1403
Keywords: amniotic fluid stem cells; amniotic epithelial stem cells; placental stem cells; regenerative therapy; immunomodulation; secretome; exosomes; degenerative diseases; inflammatory diseases
(This special issue belongs to the Section Molecular Immunology)
Molecular Research in Arabidopsis thaliana submission deadline 27 May 2022 | 6 articles | Viewed by 3810
Keywords: Arabidopsis growth and development; environmental adaptation; signaling processes; natural variation; hormone biology
(This special issue belongs to the Section Molecular Plant Sciences)
Nitric Oxide Signalling and Metabolism in Plants submission deadline 28 May 2022 | 3 articles | Viewed by 1773
Keywords: plant growth and development; postharvest; abiotic stress; fruit ripening; cut-flower; signal interactions; signal pathways; protein modification; gene regulation
(This special issue belongs to the Section Molecular Plant Sciences)
Advances in Kinase Drug Discovery 2.0 submission deadline 30 May 2022 | 1 articles | Viewed by 1290
Keywords: structure-guided drug discovery; kinase inhibitor; protein kinase; lipid kinase; nucleotide kinase; sugar kinase; fragment-based drug discovery; allosteric inhibitor; ATP-competitive inhibitor; anticancer; antibacterial; antiviral; anti-inflammatory
(This special issue belongs to the Section Macromolecules)
Nonalcoholic Fatty Liver Disease/Metabolic Associated Fatty Liver Disease: New Insights 2.0
edited by Alessandro Mantovani and
submission deadline 30 May 2022 | 3 articles | Viewed by 3458
Keywords: nonalcoholic fatty liver disease (NAFLD); metabolic associated fatty liver disease (MAFLD); nonalcoholic steatohepatitis (NASH); fatty liver; cardiovascular disease
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Understanding Traumatic Brain Injury: Mechanisms and Therapeutic Targets 3.0
edited by
submission deadline 30 May 2022 | 2 articles | Viewed by 3232
Keywords: Traumatic brain injury; TBI; Neurotrauma; Translational research; Axonal injury; Neuroimaing; Apoptosis; Head; Biomarker
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Targeted Cancer Therapy and Mechanisms of Resistance 2.0
edited by
submission deadline 30 May 2022 | 2 articles | Viewed by 2930
Keywords: cancer; kinase inhibitors; animal model; cell culture; drug resistance; signal transduction; survival; cell reprogramming; pathways; clinical trials; target therapy; cancer heterogeneity; stem cells; immunity; cell cycle; cell death inhibiting; survival; biomarkers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Target and Action Mechanism of Anti-cancer Agents 2.0
edited by
submission deadline 30 May 2022 | 1 articles | Viewed by 925
Keywords: Cancer; Conventional therapy; Targeted therapy; Immunotherapy; Chemoprevention; Molecular target; Molecular mechanism; Drug resistance; Combinatorial therapy
(This special issue belongs to the Section Molecular Immunology)
Heavy Metals Accumulation, Toxicity and Detoxification in Plants 2.0
edited by and Alessio Aprile
submission deadline 30 May 2022 | 5 articles | Viewed by 3879
Keywords: Heavy metals; Plant physiological responses to heavy metals; Phytoremediation; Heavy metal accumulation in plants; Toxicity; Tolerance; Detoxification
(This special issue belongs to the Section Molecular Plant Sciences)
Adipokines in Health and Diseases 2.0
edited by
submission deadline 30 May 2022 | 2 articles | Viewed by 2386
Keywords: adiponectin; adipose tissue; adipokines; nutrition; molecular pathways; biomarkers; health; disease
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Neuroprotection: Rescue from Neuronal Death in the Brain 2.0
edited by
submission deadline 30 May 2022 | 10 articles | Viewed by 8543
Keywords: neuroprotection; brain injury; neuronal death; neurodegeneration; neurological disorders; functional plasticity; Neuroendocrinology; neuroendocrine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Intercellular and Intracellular Communication in Human Health and Disease 2.0
edited by
submission deadline 30 May 2022 | 3 articles | Viewed by 5105
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Nanoparticles for Tumor Imaging and Therapy
edited by
submission deadline 30 May 2022 | 3 articles | Viewed by 3263
Keywords: nanoparticle; nanomedicine; polymer; drug delivery; imaging; chemotherapy; tumor-targeting; self-assembly; tumor therapy; photodynamic therapy
(This special issue belongs to the Section Molecular Oncology)
The Role of Tissue-Nonspecific Alkaline Phosphatase in Inflammation and Metabolic Syndrome 2.0
edited by
submission deadline 30 May 2022 | 1 articles | Viewed by 1557
Keywords: tissue-nonspecific alkaline phosphatase (TNAP); inflammation; adenosine nucleotides; lipopolysaccharide; metabolic syndrome; vascular calcification; alkaline phosphatase; ALPL
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Impact of Engineered Nanomaterials on Cell Mechanics submission deadline 30 May 2022 | Viewed by 586
Keywords: engineered nanomaterials; cell mechanics; nano interaction; cell membranes; cytoskeletal alterations; toxicology
(This special issue belongs to the Section Molecular Biophysics)
Pathogenesis and Treatment of Cutaneous Lymphoma
edited by
submission deadline 30 May 2022 | 7 articles | Viewed by 5137
Keywords: cutaneous lymphoma; mycosis fungoides; Sé zary syndrome; chemokine; prognosis marker; tumor microenvironment; tumor immunity; Th2; autocrine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Morpho-Mechanical Approach to Characterize the Neurodegenerative Progression submission deadline 30 May 2022 | Viewed by 502
Keywords: neurodegenerative disorders (NDs); cell mechanics; amyloid aggregates; atomic force microscopy; cell membrane; confocal investigation; spectroscopic and electrochemistry
(This special issue belongs to the Section Molecular Biophysics)
Molecular Mechanisms of Osmotic Stress Tolerance in Plants
edited by
submission deadline 30 May 2022 | Viewed by 809
Keywords: dehydration; homeostasis; osmotic stress; signaling pathways; transcription factors
(This special issue belongs to the Section Molecular Plant Sciences)
Oxidative Stress and Skeletal Muscle Function
edited by
submission deadline 30 May 2022 | 1 articles | Viewed by 1465
Keywords: oxidative stress; exercise; physical activity; skeletal muscle; muscle damage; antioxidants; reactive oxygen species; redox balance; aging; nutrition
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Functional Nanomaterials and Polymer Nanocomposites: Current Uses and Potential Applications submission deadline 30 May 2022 | 11 articles | Viewed by 7337
Keywords: smart nanoparticles; synthesis and characterization; polymer nanocomposites; energy applications; biomedical applications; environmental applications
(This special issue belongs to the Section Materials Science)
Molecular Approaches for Understanding Dengue Disease submission deadline 30 May 2022 | 1 articles | Viewed by 1272
Keywords: dengue disease; severe dengue; viral pathogenesis; viral pathogenicity; mosquito vector– virus interaction; human host– virus interactions
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Pleiotropic Effect of β-Adrenergic Receptors in Human Cancers and Other Human Diseases II
edited by Claudio Favre
submission deadline 31 May 2022 | Viewed by 152
Keywords: tumor microenvironment; β 3-adrenoreceptor; β 2-adrenoreceptor; metastasis; antioxidant activity; cancer
(This special issue belongs to the Section Molecular Oncology)
Bioactive Phytochemicals and Functional Food Ingredients in Fruits and Vegetables 2022 submission deadline 31 May 2022 | Viewed by 426
Keywords: dietary guideline; dietary fiber; essential nutrients; phytochemicals; functional food; degenerative pathologies
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Purinergic P2 Receptors: Structure and Function 2.0
edited by
submission deadline 31 May 2022 | 7 articles | Viewed by 6406
Keywords: Extracellular ATP; Purinergic signaling; P2X receptor; P2Y receptor; ATP release; Molecular structure; Molecular pathway
(This special issue belongs to the Section Molecular Biology)
Melanin in Melanosomes: Changing Properties in Malignant Melanotic Degeneration of Skin Tissue
edited by
submission deadline 31 May 2022 | 1 articles | Viewed by 1337
(This special issue belongs to the Section Molecular Biology)
Bridging the Gap between the Clinical and Regulatory Use of Plasma Rich in Growth Factors. Where Are We? submission deadline 31 May 2022 | 2 articles | Viewed by 1808
Keywords: Advanced cell therapy; Platelet-rich plasma; Wound healing; Stem cells; Patient care; Medicine; Platelets; Plasma; Patient screening; Blood processing
(This special issue belongs to the Section Molecular Pharmacology)
Plasma Bioscience and Medicine Molecular Research
edited by and Eun Ha Choi
submission deadline 31 May 2022 | 5 articles | Viewed by 3360
Keywords: plasma medicine; nonthermal plasma; biomaterials; cell biology; cancer treatments; immuno-modulations; stem cells; nanomaterials; plasma agriculture; food processing; virus inactivation; antimicrobial activities
(This special issue belongs to the Section Molecular Biophysics)
Selenium and Selenoderivatives as Emerging Bioactive Agents for Human Diseases
edited by Carmen Sanmartín, Maria Javier Ramirez, and
submission deadline 31 May 2022 | Viewed by 224
Keywords: selenoderivatives; cancer; Alzheimer; Parkinson; parasitic diseases
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Neuromelanin, Peripheral Melanin and Parkinson's Disease
edited by and Xiqun Chen
submission deadline 31 May 2022 | 1 articles | Viewed by 877
Keywords: neuromelanin; Parkinson’ s disease; substantia nigra; locus coeruleus; L-Dopamine; L-Norepinephrine; L-DOPA; melanoma
(This special issue belongs to the Section Biochemistry)
MicroRNA Signaling in Human Diseases 2.0
edited by
submission deadline 31 May 2022 | Viewed by 224
Keywords: microRNAs; inhibition of gene expression; miRNA targets; seed sequence; cell signaling; immune response; innate immune response; TLR signaling pathways; regulation of gene expression; miRNA mimics; miRNA antagonist
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Non-covalent Interaction
edited by and
submission deadline 31 May 2022 | 3 articles | Viewed by 1787
Keywords: noncovalent interactions; high-order electron correlation; density functional theory; halogen bond; machine learning techniques; molecular self-assembly; metal-organic complex; electronic excited state; surface adsorption
(This special issue belongs to the Section Materials Science)
Matrix Embedded Instructional Cues Direct Development and Tissue Repair
edited by and Anthony J Hayes
submission deadline 31 May 2022 | 7 articles | Viewed by 5426
Keywords: ECM; matrix; tissue repair; repair biology; functional recovery
(This special issue belongs to the Section Molecular Biology)
Atherosclerosis: From Molecular Biology to Therapeutic Perspective 2.0 submission deadline 31 May 2022 | 11 articles | Viewed by 8971
Keywords: Atherosclerosis; Vascular Smooth Muscle Cell; Inflammation; Endothelium; Cell Senescence; Apoptosis; Lipid Metabolism; Oxidative Stress; Nitric Oxide; Exosomes; Vascular Calcification; Cytokines; Growth Factors
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Insights into Cardiac Ion Channel Regulation 2.0
edited by and Ademuyiwa S. Aromolaran
submission deadline 31 May 2022 | 5 articles | Viewed by 4101
(This special issue belongs to the Section Molecular Biology)
The Role of Myosins in Cells
edited by Karine Gousset
submission deadline 31 May 2022 | 3 articles | Viewed by 3109
Keywords: Myosins; Muscle contraction; Motility processes; Cytokinesis; Phagocytosis; Pathogenesis; Membrane trafficking; Cell communication; Extracellular vesicles; exosomes; Tunneling nanotubes; Membrane bridges; Intracellular communication; Intercellular communication; Cell signaling
(This special issue belongs to the Section Molecular Biology)
Molecular Drivers of Responsiveness to Cancer Immunotherapy
edited by and Stephanie M. Dorta-Estremera
submission deadline 31 May 2022 | 2 articles | Viewed by 2913
Keywords: cancer vaccines; checkpoint blockade; cytokines and chemokines; immunosuppression; immunotherapy resistance; suppressor cells
(This special issue belongs to the Section Molecular Oncology)
Multidisciplinary Investigations of Nanoparticle Synthesis and Analysis for Possible Biomedical and Food Technology Applications
edited by
submission deadline 31 May 2022 | 20 articles | Viewed by 22595
Keywords: biomedical applications; nanocarriers; biomaterials; nanomaterials; contrast agents; core– shell nanostructures; liposomes; quantum dots; nanoemulsions; colloids; particle characterization; particle tracking; nanosensors; food contamination; natural nanoparticles; particle size characterization
(This special issue belongs to the Section Materials Science)
Understanding the Impacts of Neurodevelopmental Cannabinoid Exposure submission deadline 31 May 2022 | 1 articles | Viewed by 1501
Keywords: cannabinoids; neuropsychiatric disorders; schizophrenia; mood; anxiety disorders; addictions
(This special issue belongs to the Section Molecular Neurobiology)
MicroRNA, Insulin Resistance, and Metabolic Disorders
edited by
submission deadline 31 May 2022 | 2 articles | Viewed by 1594
Keywords: MicroRNA; Insulin resistance; Metabolic diseases; Insulin signaling; Diabetes; Obesity
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Mitochondrial Transport and Energy Metabolism in Health and Diseases submission deadline 31 May 2022 | 6 articles | Viewed by 6298
Keywords: mitochondrial transport; energy metabolism; ion mitochondrial transport; vitamin mitochondrial transport; protein mitochondrial transport
(This special issue belongs to the Section Molecular Biology)
Extracellular Vesicles in Reproduction 2.0
edited by Heriberto Rodriguez-Martinez, and
submission deadline 31 May 2022 | 5 articles | Viewed by 7270
Keywords: extracellular vesicles; exosomes; microvesicles; apoptotic bodies; reproductive processes; spermatogenesis; sperm maturation; seminal plasma; spermatozoa; sperm capacitation; fertility; pregnancy; immune modulation; immune tolerance; proteomics; transcriptomics; epigenomics; metabolomics
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Advanced Battery Research for Energy Storage Systems
edited by and Senentxu Lanceros-Mendez
submission deadline 31 May 2022 | 4 articles | Viewed by 4015
Keywords: Lithium-ion batteries; Lithium-oxygen batteries; Lithium-sulfur batteries; Solid state lithium battery; Sodium-ion batteries; Zinc-air batteries; Dual-ion batteries; Potassium-ion batteries; Aluminium-ion batteries; Magnessium-ion batteries; Non-aqueous redox flow
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Tumor Secretome in Translational Oncology
edited by
submission deadline 31 May 2022 | 4 articles | Viewed by 3662
Keywords: tumor microenvironment; cell subpopulations; lipid signaling; tumor secretome; metabolic targeting; therapy-induced stress; SASP
(This special issue belongs to the Section Molecular Oncology)
Stress-Related Disorders and Depression: From Molecular Basis to Therapy submission deadline 31 May 2022 | 1 articles | Viewed by 1193
Keywords: psychobiology of stress; depression; posttraumatic stress disorder; anxiety disorders; animal models; biogenic monoamines; glucocorticoids; inflammation; antidepressant and anxiolytic drugs
(This special issue belongs to the Section Molecular Neurobiology)
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