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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Circulating Tumor Cells: Pathological, Molecular and Functional Characteristics 4.0
edited by
submission deadline 16 Mar 2024 | 1 articles | Viewed by 1610
Keywords: CTC; metastasis; tumor heterogeneity; invasion; single-cell analysis; cancer dissemination; circulation; treatment response; CTC clusters
(This special issue belongs to the Section Molecular Oncology)
Transcriptional Regulation in Plant Development
edited by
submission deadline 20 Mar 2024 | 13 articles | Viewed by 17585 | Submission Open
Keywords: environmental stresses; plant development; vegetative development; plant physiology and biochemistry; transcriptional regulation; plant– environment interactions
(This special issue belongs to the Section Molecular Plant Sciences)
New Chemo-, Regio- and Stereoselective Reactions and Methods in Organic Synthesis
edited by
submission deadline 20 Mar 2024 | 8 articles | Viewed by 11306 | Submission Open
Keywords: advanced synthesis; bis-functionalization reactions; new approach; regioselective synthesis; new catalyst; stereoselective reactions; new methodology; chemoselective synthesis; new reagent; advanced method; new approach to functionalization
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Computational Approaches for the Investigation of Complex Molecular Mechanisms 2.0
edited by
submission deadline 20 Mar 2024 | 9 articles | Viewed by 10639 | Submission Open
Keywords: signal transduction; transcriptional regulation; molecular modeling; molecular dynamics; molecular docking; system biology; mathematical modeling; meta-analysis  
(This special issue belongs to the Section Molecular Informatics)
Depression: Molecular Pathology and Modern Therapy
edited by
submission deadline 20 Mar 2024 | 3 articles | Viewed by 8341 | Submission Open
Keywords: depression; neuropathology; microbiome; inflammation; targeted interventions
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Biomarkers in Cardiovascular Disease submission deadline 20 Mar 2024 | 5 articles | Viewed by 7660 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Modeling Neurological Disorders in Experimental Animals: New Insights and Emerging Roles 3.0
edited by
submission deadline 20 Mar 2024 | 8 articles | Viewed by 7242 | Submission Open
Keywords: neurological disorders; animal models; developmental models; genetic models; molecular mechanisms; genetic analysis; drug efficacy testing
(This special issue belongs to the Section Molecular Neurobiology)
Melanosome Transport/Transfer and Melanin Pigmentation in the Skin 2.0 submission deadline 20 Mar 2024 | 2 articles | Viewed by 6863 | Submission Open
Keywords: endocytosis; exocytosis; fibroblast; keratinocyte; melanin; melanocyte; melanosome; pigmentation; trafficking; transfer
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Sex Hormones and Sex Differentiation
edited by
submission deadline 20 Mar 2024 | 3 articles | Viewed by 6413 | Submission Open
Keywords: sex differentiation; sex hormones; testis; ovary; gene expression; transcription; steroids; male; female
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Oxidative Stress and Inflammation in Parkinson’s Disease and Mood Disorders submission deadline 20 Mar 2024 | 2 articles | Viewed by 3631 | Submission Open
Keywords: oxidative stress; inflammation; Parkinson’ s disease; mood disorders; depression; mechanisms of depression; cytokines; animal models; human study
(This special issue belongs to the Section Molecular Neurobiology)
New Insights of DNA Methylation submission deadline 20 Mar 2024 | 2 articles | Viewed by 3127 | Submission Open
Keywords: DNA methylation; epigenetics; aging; cancer; neurodegenerative diseases; forensic sciences; epigenetic clocks
(This special issue belongs to the Section Molecular Genetics and Genomics)
Plant Population Genomics
edited by
submission deadline 20 Mar 2024 | 3 articles | Viewed by 3010 | Submission Open
Keywords: plant population genomics; GWAS models; genomic prediction; machine learning forecasting; the omnigenic model
(This special issue belongs to the Section Molecular Plant Sciences)
Multi-Omics Approaches for Health and Disease
edited by
submission deadline 20 Mar 2024 | 3 articles | Viewed by 2999 | Submission Open
Keywords: metabolomics and metaproteomics; genomics; microbiomes; mycobiome and virome; omics integration workflows; network modelling; and platforms; metabolic pathway analysis toolboxes (R; MATLAB; Python; etc.); systems biology and biomarker discovery; multi-organism interactions; e.g.; host– parasite– microbiome interaction; precision health; environment; agriculture and food
(This special issue belongs to the Section Biochemistry)
New Molecular Research and Perspective: Enzyme and Its Catalysis
edited by
submission deadline 20 Mar 2024 | 1 articles | Viewed by 2391 | Submission Open
Keywords: enzyme; catalysis; catalysts; enzyme reaction
(This special issue belongs to the Section Biochemistry)
Protein-Polysaccharide Complexes: Structure and Physico-Chemical Properties
edited by
submission deadline 20 Mar 2024 | 2 articles | Viewed by 2131 | Submission Open
Keywords: protein-polysaccharide complexes; structure; physico-chemical properties; supramolecular systems; immobilization
(This special issue belongs to the Section Molecular Informatics)
Selected Papers Associated with 2023 STEMNET MEETING
edited by and Ivana Ferrero
submission deadline 20 Mar 2024 | 3 articles | Viewed by 1431 | Submission Open
Keywords: mesenchymal stromal cell; advanced cell therapy; translational medicine; stem cell in veterinary; organoid; secretome
(This special issue belongs to the Section Biochemistry)
State-of-the-Art Molecular Biology in France
edited by
submission deadline 20 Mar 2024 | 1 articles | Viewed by 1424 | Submission Open
(This special issue belongs to the Section Molecular Biology)
The Biology and Therapeutic Potential of Metalloproteases
edited by and Dimitris Georgiadis
submission deadline 20 Mar 2024 | 2 articles | Viewed by 1318 | Submission Open
Keywords: metalloproteases; enzymes; inhibitors; mechanisms; structure; drug targets; probes; proteolysis; disease mechanisms; metal
(This special issue belongs to the Section Biochemistry)
New Molecular Insights into Ischemia/Reperfusion
edited by
submission deadline 20 Mar 2024 | 1 articles | Viewed by 1232 | Submission Open
Keywords: vital organs; ischemic injury; cell and organ dysfunction; oxidative stress; inflammation; excitotoxicity
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Bioprocesses and Biotechnology Related to Extremophiles—Molecular Aspects submission deadline 20 Mar 2024 | 1 articles | Viewed by 1015 | Submission Open
Keywords: waste circularity; plastic recycle; lignocellulose; extremozymes; microbial ecology; microbial bioprocess
(This special issue belongs to the Section Molecular Microbiology)
Proteasomes and Cellular Senescence: An Age-Related Connection
edited by
submission deadline 20 Mar 2024 | Viewed by 539 | Submission Open
Keywords: proteasomes; aging; proteasome receptors; post-translational modification
(This special issue belongs to the Section Molecular Biology)
Molecular Mechanisms and Treatment of Cardiovascular Diseases
edited by
submission deadline 20 Mar 2024 | Viewed by 421 | Submission Open
Keywords: cardiovascular diseases; molecular pathology; microRNAs; diabetes; cardiovascular complications of diabetes
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Emerging Molecular Signaling Pathways and Therapeutic Targets for Urological Cancer
edited by
submission deadline 20 Mar 2024 | Viewed by 313 | Submission Open
Keywords: biomarkers; genomics; targeted therapies; disease progression; cancer metastasis and signaling pathways
(This special issue belongs to the Section Molecular Oncology)
New Applications of Natural Compounds as Functional Additives of Foods submission deadline 20 Mar 2024 | Viewed by 296 | Submission Open
Keywords: antibacterial activity; anti-inflammatory activity; antioxidant activity; bioactive compounds; foodomics; functional food; green extraction techniques; health promotion; immunonutrition; metabolome alterations; microbiome; nutraceuticals; oxidative stress; polyphenols; vitamins
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Advances in Nutritional Approach to the Neurodegenerative Diseases submission deadline 20 Mar 2024 | Viewed by 250 | Submission Open
Keywords: neurodegenerative disease; inflammation and oxidation; the interaction of brain and nutrition; nutritional preventive and therapeutic approaches; gut microbiota– brain axis; improving the quality of life in patients with neurodegenerative diseases
(This special issue belongs to the Section Molecular Neurobiology)
Recent Advances in Immunotherapy of Multiple Myeloma
edited by Catarina Geraldes
submission deadline 20 Mar 2024 | Viewed by 211 | Submission Open
Keywords: multiple myeloma; immunotherapy; CAR-T cell therapy; bispecific antibodies; monoclonal antibodies; antibody– drug conjugates; resistance mechanisms
(This special issue belongs to the Section Molecular Oncology)
Immunophenotyping in Autoimmune Diseases and Cancer, 4th Edition submission deadline 20 Mar 2024 | Viewed by 206 | Submission Open
Keywords: immunophenotyping; immune regulation; multiparameter cytometry; immuno-oncology; anti-tumor immunity; autoimmunity; cancer immunology; protein– protein interactions; structure/function relationships; sulfur amino acids
(This special issue belongs to the Section Molecular Immunology)
Clinical and Biological Perspectives on Erythrocyte Apoptosis
edited by Syed Qadri, Rosi Bissinger and
submission deadline 20 Mar 2024 | Viewed by 150 | Submission Open
Keywords: erythrocytes; apoptosis; eryptosis; anemia; systemic diseases
(This special issue belongs to the Section Molecular Biology)
New Trends in Molecular Biosensors submission deadline 20 Mar 2024 | Viewed by 140 | Submission Open
Keywords: SPR biosensors; electrochemical biosensors; cantilever based biosensors; organic electronic based biosensors; lipid membranes
(This special issue belongs to the Section Biochemistry)
Exploring the Glioblastoma Complexity: New Perspectives in the Molecular and Imaging Fields submission deadline 22 Mar 2024 | 3 articles | Viewed by 3533 | Submission Open
Keywords: glioblastoma; imaging techniques; molecular techniques; liquid biopsy; in vitro model; in vivo model
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Application of Fluorescence Imaging and Super-Resolution Imaging in Molecular Biology
edited by
submission deadline 24 Mar 2024 | Viewed by 540 | Submission Open
Keywords: fluorescence imaging; super-resolution imaging; molecular biology; disease; biomolecules; organelles; morphologies of cells; iPS cells; organoids; molecular biology
(This special issue belongs to the Section Molecular Biophysics)
Promising Natural Products for Animal and Human Skin Disorders
edited by
submission deadline 24 Mar 2024 | Viewed by 335 | Submission Open
Keywords: skin; inflammation; molecular pathways; natural compound
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Roles and Function of Extracellular Vesicles in Diseases 2.0
edited by
submission deadline 25 Mar 2024 | 7 articles | Viewed by 10991 | Submission Open
Keywords: extracellular vesicle; exosome; disease; roles and function
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Research of Ocular Pathology
edited by
submission deadline 25 Mar 2024 | 8 articles | Viewed by 9360 | Submission Open
Keywords: ocular pathologies; dry eye; glaucoma; retinal diseases; oxidative stress; inflammation; molecular treatments; molecular biomarkers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Calcium Homeostasis in Skeletal Muscle Function, Plasticity and Disease submission deadline 25 Mar 2024 | 5 articles | Viewed by 7862 | Submission Open
Keywords: skeletal muscle; intracellular calcium; excitation contraction coupling; muscle force; myopathies; aging
(This special issue belongs to the Section Biochemistry)
Recent Advances in Wound Healing submission deadline 25 Mar 2024 | 6 articles | Viewed by 6804 | Submission Open
Keywords: management of wounds; nanobiomaterials; infection control; chronic wound; biofilm infections; wound dressings; tissue engineering; wound healing
(This special issue belongs to the Section Molecular Biology)
Current Advances in Peptide Inhibitors
edited by
submission deadline 25 Mar 2024 | 4 articles | Viewed by 5577 | Submission Open
Keywords: peptides; peptide inhibitors; drug development; peptide modifications; PK/PD; delivery; endogenous peptide inhibitors
(This special issue belongs to the Section Molecular Pharmacology)
Hepatitis C Virus: Pathogenetic Mechanisms, Residual Problems after Cure and Hopes for Elimination
edited by
submission deadline 25 Mar 2024 | 4 articles | Viewed by 5041 | Submission Open
Keywords: epigenetic signatures; public health; vaccines; hepatocellular carcinoma; extrahepatic cancer; liver decompensation; elimination; diagnosis; linkage to care
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Genomics in Neurodegenerative Diseases
edited by
submission deadline 25 Mar 2024 | 2 articles | Viewed by 4629 | Submission Open
Keywords: neurodegenerative disorders; redox systems; proteostasis; seeding misfolded proteins; antimicrobial peptides; epigenome
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Insight into Novel Coatings: Design, Synthesis, and Applications submission deadline 25 Mar 2024 | 2 articles | Viewed by 3943 | Submission Open
Keywords: composite coatings; protective coatings; antibacterial coatings; superhydrophobic coatings; superhydrophilic coatings; anti-icing coatings; bioactive coatings; photocatalytic coatings  
(This special issue belongs to the Section Materials Science)
Artificial Intelligence in Biomarker Discovery 2.0
edited by
submission deadline 25 Mar 2024 | 2 articles | Viewed by 3014 | Submission Open
Keywords: machine learning; biomarker; precision medicine; artificial intelligence; text mining; automation; genomics; epigenomics; proteomics; big data; clinical; diagnostic; bioinformatic
(This special issue belongs to the Section Molecular Informatics)
Breakthroughs in Diagnostic Prediction and Fundamental Therapeutics of Dementia and Movement Disorders submission deadline 25 Mar 2024 | 1 articles | Viewed by 2303 | Submission Open
Keywords: Parkinson’ s disease; dementia with Lewy bodies; Alzheimer’ s disease; pathogenic protein; biomarker; therapeutic target; drug
(This special issue belongs to the Section Molecular Neurobiology)
Autophagy, Cellular Senescence and Oxidative Stress in Ageing and Age-Related Diseases
edited by
submission deadline 25 Mar 2024 | 1 articles | Viewed by 1980 | Submission Open
Keywords: autophagy; oxidative stress; antioxidants; homeostasis; senescence; ageing; age-related diseases; reactive oxygen species; macromolecular damage; cytotoxic stress
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Regulatory Mechanisms of Non-coding RNA in Cardiovascular Disease
edited by and Sanjeet Avtaar Singh
submission deadline 25 Mar 2024 | 2 articles | Viewed by 1896 | Submission Open
Keywords: non-coding RNA; cardiovascular disease; molecular regulation; lncRNA; miRNA; circRNA; gene expression; pathogenesis; heart disease; therapeutic targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
From Molecular Insights to Novel Therapies: Neurological Diseases
edited by
submission deadline 25 Mar 2024 | 1 articles | Viewed by 1673 | Submission Open
Keywords: neurological diseases; neurodegenerative diseases; epilepsy; mental illness; transgenic animal models; molecular pathways; metabolism disabilities; mitochondrial dysfunction; oxidative stress; disturbances in epigenetic regulation
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Mechanisms of Infection for Pathogenic Bacteria 2.0
edited by
submission deadline 25 Mar 2024 | 2 articles | Viewed by 1392 | Submission Open
Keywords: bacterial pathogen; infection; molecules; host defense; infectious diseases; human health; infection models; virulence factors
(This special issue belongs to the Section Molecular Microbiology)
Novel Therapies for Schizophrenia: Beyond Dopamine
edited by
submission deadline 25 Mar 2024 | 1 articles | Viewed by 1125 | Submission Open
Keywords: schizophrenia; dopamine signaling; nondopaminergic pathways; microbial translocation; cognitive rehabilitation; delirium; psychopharmacology; novel treatment strategies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms of Pregnancy Complications submission deadline 25 Mar 2024 | 2 articles | Viewed by 866 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Sights into the Serotonin System, Obesity and Diabetes
edited by
submission deadline 25 Mar 2024 | 1 articles | Viewed by 659 | Submission Open
Keywords: serotonin; serotonin receptor; serotonin transporter; energy metabolism; nutrients; microbiota; hormones; obesity; hepatosteatosis; diabetes
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Dysfunctional Neural Circuits and Impairments in Brain Function submission deadline 25 Mar 2024 | 1 articles | Viewed by 644 | Submission Open
Keywords: neural circuits; dysfunctional circuits; neuropsychiatric disorders; optical recording; voltage-sensitive dyes; genetically encoded optical indicators; local brain activity; whole brain activity; cognitive impairments; behavioral test
(This special issue belongs to the Section Molecular Neurobiology)
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