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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Microbiome in Cancer: From Pathogenesis to Therapeutic Innovation

edited by

Francesca Benedetti

and

Davide Zella

submission deadline 20 May 2026 | 1 articles | Viewed by 1796 | Submission Open

Keywords: microbiome; cancer; anticancer drugs; chemoresistance; immune modulation

(This special issue belongs to the Section Molecular Microbiology)

Acute Leukemia: From Basic Research to Clinical Application, Second Edition

edited by

Luca Lo Nigro

submission deadline 20 May 2026 | 3 articles | Viewed by 1782 | Submission Open

Keywords: acute lymphoblastic leukemia (ALL); acute myeloid leukemia (AML); genomic findings; post-genomic findings; targeted therapies; immunotherapies; novel markers

(This special issue belongs to the Section Molecular Oncology)

Mitochondria as a Therapeutic Target for Anti-Cancer Drugs

edited by

Dalia Marija Kopustinskiene

submission deadline 20 May 2026 | Viewed by 1703 | Submission Open

Keywords: mitochondria; cancer; apoptosis; oxidative phosphorylation; Warburg effect; cardiolipin; inflammation

(This special issue belongs to the Section Molecular Oncology)

Cardiomyopathy: From Molecular Pathology to Treatment

edited by

Andrea Sonaglioni

and

Gian Luigi Nicolosi

submission deadline 20 May 2026 | 2 articles | Viewed by 1659 | Submission Open

Keywords: obesity; myocardial fibrosis; subclinical myocardial dysfunction; fibrotic remodeling; microRNAs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Research in Nanophotonics and Biophotonics

edited by

Prabhakar Pradhan

submission deadline 20 May 2026 | 1 articles | Viewed by 1645 | Submission Open

Keywords: biophotonics; spectroscopy; light scattering; Raman/FTIR; cancer; Alzheimer's and Parkinson’ s diseases; nanophotonics; plasmonics; nano-biophotonics

(This special issue belongs to the Section Molecular Nanoscience)

Surfactants: Design, Synthesis and Application

edited by

Urszula Bazylinska

submission deadline 20 May 2026 | 1 articles | Viewed by 1617 | Submission Open

Keywords: surfactants; adsorption phenomena; critical micellar concentration (CMC); hydrophilic– lipophilic balance (HLB); critical packing parameter (CPP); emulsion formulations; vesicular and non-vesicular origin nanocarriers; drug delivery; theranostics

(This special issue belongs to the Section Materials Science)

Recent Advances in the Biological Function of Tyrosinase

edited by

Kazumasa Wakamatsu

submission deadline 20 May 2026 | 1 articles | Viewed by 1603 | Submission Open

Keywords: tyrosinase-related proteins; tyrosinase; melanogenesis; copper; zinc; metal enzymes; tyrosinase inhibitor; pigmentation disorders

(This special issue belongs to the Section Molecular Biology)

Extracellular Vesicles in Microorganisms

edited by

Bao-Hong Lee

and

Tang-Long Shen

submission deadline 20 May 2026 | 1 articles | Viewed by 1599 | Submission Open

Keywords: microbial extracellular vesicles; outer membrane vesicles; host– microbe interaction; interkingdom communication; EV cargo; microbial therapeutics; microbiota; nanovesicles; small RNAs; gut– brain axis

(This special issue belongs to the Section Molecular Microbiology)

The Role of Extracellular Vesicles in Disease and Therapeutic Applications

edited by Sunyoung Park

submission deadline 20 May 2026 | 1 articles | Viewed by 1569 | Submission Open

Keywords: extracellular vesicles (EVs); disease biomarkers; EV-based therapeutics; cancer diagnosis; drug delivery; immune modulation; regenerative medicine

(This special issue belongs to the Section Molecular Biology)

Current and Emerging Therapeutic Approaches for MASLD

edited by

Chrysoula Boutari

submission deadline 20 May 2026 | 1 articles | Viewed by 1505 | Submission Open

Keywords: MASLD; MASH; GLP-1 agonists; anti-inflammatory agents; anti-obesity drugs; FGF-21

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pathogenesis and Treatment of Prostate Cancer

edited by

Vincenzo Fiorentino

submission deadline 20 May 2026 | 1 articles | Viewed by 1500 | Submission Open

Keywords: prostate cancer; pathogenesis; genetic mutations; target therapy; surgery; radiation therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Advances in Metal Nanoparticles

edited by

Emilia Konował

submission deadline 20 May 2026 | 2 articles | Viewed by 1480 | Submission Open

Keywords: metal nanoparticles; molecular-level mechanisms; functional nanostructures; environmental nanotechnology; nanoparticle stability; catalysis; hybrid nanomaterials; bimetallic systems; ligand– nanoparticle interactions

(This special issue belongs to the Section Molecular Nanoscience)

New Advances in Reproductive Immunology and Pathology

edited by Silvia Giugliano

submission deadline 20 May 2026 | 1 articles | Viewed by 1473 | Submission Open

Keywords: maternal– fetal immune tolerance; reproductive immunopathology; cytokine signaling in pregnancy; immune-related infertility; metabolome-immune crosstalk; microbiome influence on fertility

(This special issue belongs to the Section Molecular Immunology)

Molecular Insights into Antimicrobial Agents: Mechanisms and Applications

edited by

Aleksandra Maria Kocot

submission deadline 20 May 2026 | 2 articles | Viewed by 1463 | Submission Open

Keywords: antimicrobial compounds; antibacterial activity; antibiotic resistance; pathogen-tailored therapeutic targeting; novel antimicrobials; molecular aspects of the mechanisms of action of antibacterial substances; effectiveness of antibacterial substances

(This special issue belongs to the Section Biochemistry)

Sarcomas: From Molecular Signatures to Morphologic Patterns

edited by

Isidro Machado

submission deadline 20 May 2026 | 1 articles | Viewed by 1438 | Submission Open

Keywords: sarcomas; histopathology; molecular pathology; FISH; gene fusion in sarcomas

(This special issue belongs to the Section Molecular Oncology)

Multifunctional Magnetic Nanoparticles: Synthesis, Properties, and Biomedical Applications

edited by

Krishtappa Manjunatha

submission deadline 20 May 2026 | Viewed by 1404 | Submission Open

Keywords: magnetic nanoparticles; molecular functionalization; magnetocaloric materials; drug delivery systems; molecular imaging; magnetic memory; nanocomposites; nanophosphors; environmental remediation; energy storage materials; magnetic biosensing; biofunctional interfaces

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Defects of Naturally Occurring Mutations

edited by Ya-Xiong Tao

submission deadline 20 May 2026 | 1 articles | Viewed by 1403 | Submission Open

Keywords: protein misfolding; loss of function; gain of function; pharmacological chaperone; precision medicine

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Perspectives in Tissue Engineering and Regenerative Medicine

edited by

Sorina Dinescu

submission deadline 20 May 2026 | 1 articles | Viewed by 1357 | Submission Open

Keywords: 3D scaffolds; personalized regenerative therapies; tissue engineering; stem cells; bone regeneration; regenerative biomarkers; cell– scaffold interactions; nanomaterials

(This special issue belongs to the Section Molecular Biology)

Heterocyclic Compounds: Molecular Modelling Studies and Pharmacological Investigation

edited by

Gabriella Guerrini

and

Maria P. Giovannoni

submission deadline 20 May 2026 | 1 articles | Viewed by 1336 | Submission Open

Keywords: heterocycles; fused heteocycles; synthesis; small-molecules; natural product; drug design; biological studies; molecular modeling

(This special issue belongs to the Section Biochemistry)

Molecular Adaptation Mechanisms of Plants to Environmental Stress

edited by

Michael Moustakas

submission deadline 20 May 2026 | 1 articles | Viewed by 1320 | Submission Open

Keywords: signal perception; signal transduction; post-translational modifications; stress response genes; reactive oxygen species; osmoprotectant; antioxidants; plant hormones; stress-related proteins; climate change; biotic stress; abiotic stress

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Research in Ocular Inflammation and Infection

edited by

Christine Fardeau

submission deadline 20 May 2026 | 1 articles | Viewed by 1264 | Submission Open

Keywords: ocular infections; uveitis; choroiditis; masquerade syndrome; pseudo-uveitis; intraocular lymphoma; retinal dystrophy; ocular inflammation; neuroinflammation; immunotherapy-induced uveitis; autoimmune eye diseases; sarcoidosis; OCT; indocyanine green angiography

(This special issue belongs to the Section Molecular Immunology)

Chlamydia trachomatis Pathogenicity and Disease (Third Edition)

edited by

Rosa Sessa

and

Marisa Di Pietro

submission deadline 20 May 2026 | 1 articles | Viewed by 1230 | Submission Open

Keywords: Chlamydia trachomatis; virulence factors; host susceptibility or resistance; innate and adaptive immune responses; genetic studies; cervico-vaginal microbiota; clinical outcomes with molecular study

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Biological Breeding and Molecular Biology of Tropical Crops

edited by Yongzan Wei

submission deadline 20 May 2026 | 1 articles | Viewed by 1202 | Submission Open

Keywords: tropical crops; biological breeding; tropical fruit; molecular biology; gene editing; transcrip-tional regulation; genomics

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Evolution and Genetic Diversity in Viruses

edited by

Jennifer H. Lun

submission deadline 20 May 2026 | 1 articles | Viewed by 1187 | Submission Open

Keywords: viral mutation; recombination reassortment; viral genomics; quasispecies dynamics; antiviral resistance; viral phylogenetics; zoonotic transmission; genomic surveillance

(This special issue belongs to the Section Molecular Microbiology)

Omics Approaches to Unravel Plant Responses to Habitat Stresses

edited by

Claudia Uhde-Stone

submission deadline 20 May 2026 | 1 articles | Viewed by 1177 | Submission Open

Keywords: omics; multi-omics; high-throughput technologies; biotic stress; abiotic stress; environmental stress; crosstalk; translational biology; crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Chessboard: How Plants and Insects Outsmart Each Other

edited by

Mateusz Labudda

submission deadline 20 May 2026 | 1 articles | Viewed by 1176 | Submission Open

Keywords: acarology; biotic stress; entomology nitric oxide; oxidative stress; phytopathology; reactive nitrogen species; reactive oxygen species

(This special issue belongs to the Section Molecular Plant Sciences)

Abscisic Acid, a New Old Friend to Regulate Abiotic Stress Tolerance in Plants

edited by Marta Marina Pérez-Alonso and

Miguel González-Guzmán

submission deadline 20 May 2026 | 1 articles | Viewed by 1133 | Submission Open

Keywords: abscisic acid (ABA); ABA perception; ABA signaling network; abiotic stress; hormonal crosstalk; crop species; stress tolerance; plant productivity; agriculture

(This special issue belongs to the Section Molecular Plant Sciences)

Mitochondrial Dysfunction and Oxidative Stress in Human Diseases

edited by

Eiko Nakamaru-Ogiso

submission deadline 20 May 2026 | 1 articles | Viewed by 915 | Submission Open

Keywords: mitochondrial dysfunction; oxidative stress; reactive oxygen species

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Regulatory Mechanisms in Kidney Development and Function

edited by Gary F. Gerlach

submission deadline 20 May 2026 | 1 articles | Viewed by 903 | Submission Open

Keywords: drosophila nephrocyte; zebrafish pronephros; mesonephros; murine nephrogenesis; slit diaphragm; podocytes; junctions; tubule; mesenchymal-to-epithelia transition (MET); epithelial-to-mesenchymal transition (EMT); tubule segmentation; transcription factors; signaling pathways; foot processes; cytoskeleton; brush boarder; intercalated cells; renin angiotensin; diabetic kidney disease; podocytopathies; FSGS; minimal change disease; IgAN

(This special issue belongs to the Section Molecular Biology)

Computational Approaches in Biomedicine: Innovations and Insights

edited by

Carlos Leon

submission deadline 20 May 2026 | Viewed by 853 | Submission Open

Keywords: computational biomedicine; artificial intelligence; machine learning; omic technologies; system biology; medical imaging; structural biology; drug discovery

(This special issue belongs to the Section Molecular Informatics)

The Role of Fibrinolytic Factors in Disease

edited by

Yosuke Kanno

submission deadline 20 May 2026 | Viewed by 822 | Submission Open

Keywords: fibrinolysis; plasminogen; plasmin; α 2-antiplasmin; uPA; uPAR; tPA; PAI-1

(This special issue belongs to the Section Molecular Biology)

Advances in Glyco-Based Anticancer Agents

edited by Pedro Colinas

submission deadline 20 May 2026 | 1 articles | Viewed by 813 | Submission Open

Keywords: carbohydrates; cancer; Warburg effect; glycolysis; enzyme inhibitors; transporters inhibitors; docking simulations; tumor microenvironment

(This special issue belongs to the Section Biochemistry)

Lipoproteins—Opportunities for the Development of Nanotherapeutics in Chronic Disease

edited by

Thomas Grewal

submission deadline 20 May 2026 | Viewed by 802 | Submission Open

Keywords: lipoproteins; LDL; HDL; nanotherapeutics; chronic disease; targeted therapy; drug delivery

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Biomarkers in Pancreatic Diseases

edited by

Laura Gaman

and

Mihaela Badea

submission deadline 20 May 2026 | Viewed by 787 | Submission Open

Keywords: pancreatic disease; pancreatic cancer; pancreatitis; biomarker; RNA

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Drug and Non-Drug Treatment of Cerebral Diseases

edited by

Silvia Carloni

submission deadline 20 May 2026 | 1 articles | Viewed by 761 | Submission Open

Keywords: cerebral diseases; cerebral ischemia; neonatal hypoxic-ischemic encephalopathy (HIE); neuroprotection; therapeutic hypothermia; neurorehabilitation; oxidative stress; stem cell therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research in Genetic Causes of Adult-Onset Disorders

edited by

Claudio Graziano

submission deadline 20 May 2026 | Viewed by 757 | Submission Open

Keywords: ADPKD; cardiomyopathy; CADASIL; amyloidosis; MODY; late-onset hearing impairment; penetrance; adult onset

(This special issue belongs to the Section Molecular Genetics and Genomics)

Epigenetic Mechanisms in Human Diseases: From Molecular Pathogenesis to Therapeutic Interventions

edited by Silvia Consalvi

submission deadline 20 May 2026 | 1 articles | Viewed by 728 | Submission Open

Keywords: epigenetics; DNA methylation; histone modifications; chromatin remodeling; non-coding RNAs; epigenomic profiling; epigenetic biomarkers; epigenetic therapy; epigenetic drugs; epigenome editing; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Basis of Inorganic Phosphate Transport Regulation in Protozoan Parasites

edited by

Jose Roberto Meyer-Fernandes

submission deadline 20 May 2026 | 1 articles | Viewed by 654 | Submission Open

Keywords: inorganic phosphate transport; protozoan parasites; cell proliferation

(This special issue belongs to the Section Molecular Biology)

Advanced Research on Comparative Reproductive Physiology

edited by

Heriberto Rodriguez-Martinez

and

Manuel Álvarez-Rodríguez

submission deadline 20 May 2026 | Viewed by 653 | Submission Open

Keywords: andrology; sperm; oocyte; gamete interactions; reproductive morphology; reproductive endocrinology; omics; epigenetics; pregnancy; all animal species

(This special issue belongs to the Section Molecular Biology)

Advances in Targeted Cancer Therapy and Side-Effect Management

edited by Wei-Min Chang

submission deadline 20 May 2026 | 1 articles | Viewed by 652 | Submission Open

Keywords: targeted cancer therapy; novel therapy approaches; personalized treatment; small molecule inhibitors; combination strategies; multi-omics integration; proton therapy; reduced cancer treatment side effects; therapeutic resistance; biomarkers

(This special issue belongs to the Section Molecular Oncology)

Antituberculous Drugs: Progress and Challenges

edited by Ana Maria Telmo Dias Pereira Vicente Cabral and

Ana Cristina Faria Ribeiro

submission deadline 20 May 2026 | Viewed by 607 | Submission Open

Keywords: antituberculostatic drugs; carriers; bioavailability; delivery systems

(This special issue belongs to the Section Molecular Pharmacology)

Electromagnetic-Biological Interactions: Towards Precision Medicine and Novel Therapies

edited by Richard H. W. Funk

submission deadline 20 May 2026 | Viewed by 569 | Submission Open

Keywords: electromagnetic treatment; magnetic pulses; biological interface; cell biology; molecular biology; signaling cascades; clinical treatment; monitoring; sensors

(This special issue belongs to the Section Molecular Biophysics)

Bioactive Peptides: Function, Metabolism and Synthesis

edited by

Leandro Mantovani de Castro

submission deadline 20 May 2026 | Viewed by 562 | Submission Open

Keywords: bioactive peptides; antimicrobial peptides; antitumoral peptides; neurodegenerative diseases; metabolic diseases; chemical synthesis; cellular proteolysis; mass spectrometry; peptidomics; intracellular peptides; micropeptides

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Perineuronal Nets and Fear Memories Erasure: State of the Art and Future Directions

edited by

Andrea Poli

submission deadline 20 May 2026 | Viewed by 530 | Submission Open

Keywords: perineuronal nets (PNNs); extracellular matrix (ECM); fear erasure; traumatic memories; PTSD; translation research; clinical treatment; therapeutical strategies

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Applications of Nanoparticles in Cancer Therapy

edited by Carlos Caro and Iñigo Martínez-Zubiaurre

submission deadline 20 May 2026 | Viewed by 527 | Submission Open

Keywords: nanomedicine; molecular biology of cancer; advanced therapies; tumor microenvironment; cellular crosstalk

(This special issue belongs to the Section Materials Science)

Crosstalk Between Bioactive Compounds and Disease

edited by

Mónica Carrera

submission deadline 20 May 2026 | Viewed by 524 | Submission Open

Keywords: bioactive compounds; human health; omics technologies; nanotechnology; drug development

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Targeted Protein Degradation: From Molecular Mechanisms to Therapeutic Applications

edited by

Asim Debnath

submission deadline 20 May 2026 | Viewed by 519 | Submission Open

Keywords: targeted protein degradation; ubiquitin– proteasome system; PROTAC; drug design; medicinal chemistry

(This special issue belongs to the Section Molecular Pharmacology)

Advances in Understanding Respiratory Virus–Host Interactions

edited by Kun Li

submission deadline 20 May 2026 | Viewed by 514 | Submission Open

Keywords: respiratory viruses; virus– host interactions; molecular mechanisms; viral replication; host– immune response; molecular pathogenesis; molecular signaling; antiviral strategies

(This special issue belongs to the Section Molecular Microbiology)

Molecular Pharmacological Advances in Gastrointestinal Health

edited by

Mirjana Stupnisek

submission deadline 20 May 2026 | Viewed by 508 | Submission Open

Keywords: gastrointestinal disorders; gastrointestinal healing; gut microbiota; inflammatory bowel disease; irritable bowel syndrome; gastrointestinal cancer; Crohn’ s disease; metabolic syndrome; cytoprotective agents; nonsteroidal anti-inflammatory drugs’ toxicity

(This special issue belongs to the Section Molecular Pharmacology)

Autophagy and Apoptosis in Mammal Cells

edited by Kaja Urbańska and Anna Litwiniuk

submission deadline 20 May 2026 | Viewed by 432 | Submission Open

Keywords: autophagy; apoptosis; cellular homeostasis; intra- and intercellular crosstalk; autophagic cell death; programmed cell death

(This special issue belongs to the Section Molecular Biology)

Displaying special issue 201-250 on page 5 of 68.

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