Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Patterns across Developmental Scales submission deadline 10 May 2024 | Viewed by 307 | Submission Open
Keywords: patterning; organ; cells; differentiation; proliferation; death; biophysics
Molecular Insights: Bridging the Gap between Aging, Neurodegenerative Disease, and Cancer from Bench to Bedside
edited by
submission deadline 10 May 2024 | Viewed by 304 | Submission Open
Keywords: aging; neurodegeneration; cancer; cellular senescence; SASP; stem cell exhaustion; epigenetics; metabolism; mitochondria; proteostasis; inflammation; immune aging; DNA damage; genomic instability; cell cycle; proliferation; risk genes; biomarkers; therapeutics; disease models
(This special issue belongs to the Section Cellular Aging)
Microglia in Neurological Diseases submission deadline 15 May 2024 | 6 articles | Viewed by 15247 | Submission Open
(This special issue belongs to the Section Cells of the Nervous System)
Stromal Cells—Structure, Function and Therapeutics Development
edited by Veronika Lukacs-Kornek
submission deadline 15 May 2024 | 5 articles | Viewed by 10509 | Submission Open
(This special issue belongs to the Section Cell and Gene Therapy)
Model Systems for Human Disease and Medicine: From Advanced Cell and Tissue Culture to In Silico Methods
edited by
submission deadline 15 May 2024 | 5 articles | Viewed by 7621 | Submission Open
Keywords: modelling; human model systems; in vitro; cells; stem cells; pluripotent stem cells; iPSC; tissue; organoid; organ-on-a-chip; cell-on-a-chip; in silico; disease; cancer; regenerative medicine; diagnostics; therapeutics
(This special issue belongs to the Section Cell Methods)
Model Systems and Candidate Genes for Inherited Cardiomyopathies submission deadline 15 May 2024 | 4 articles | Viewed by 6735 | Submission Open
Keywords: cardiovascular genetics; cardiomyopathy; animal model; RNA expression; microRNA
(This special issue belongs to the Section Cells of the Cardiovascular System)
Role of Inflammasome Activation in Innate and Adaptive Immunity submission deadline 15 May 2024 | 3 articles | Viewed by 4470 | Submission Open
Keywords: inflammasome; caspase-1; ASC specks; pyroptosis; innate immunity; adaptive immunity; sterile inflammation; cell death pathways; apoptosis; autophagy; NETosis; PANoptosis; ferroptosis; necroptosis; neurodegenerative disease; trauma; cerebral ischemia; biomarkers
(This special issue belongs to the Section Cellular Immunology)
Advances in Retinal Disease Treatments Based on Cell Therapy and Regenerative Medicine submission deadline 15 May 2024 | 1 articles | Viewed by 1103 | Submission Open
Keywords: retinal diseases; cell therapy; regenerative medicine; visual function restoration; tissue regeneration; neuronal survival; promising therapeutic strategies
(This special issue belongs to the Section Cell Methods)
Nucleic Acid Sensing in Respiratory Diseases—Series 2
edited by and Remo Russo
submission deadline 15 May 2024 | Viewed by 102 | Submission Open
Keywords: cGAS; STING; inflammasome; TLR; infection; cell stress; lung inflammation; inhibitors
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Metallodrugs against Cancer Cells: Mechanisms of Action and Molecular Targets
edited by and Elisa Abás
submission deadline 15 May 2024 | Viewed by 89 | Submission Open
Keywords: cell death; cytotoxicity; molecular mechanism; cell imaging; theragnostic; photodynamic therapy; chemotherapy; gene expression; drug uptake; SAR studies
The Complex and Multifaceted Role of Damage Associated Molecular Patterns (DAMPs) in COPD
edited by
submission deadline 20 May 2024 | Viewed by 100 | Submission Open
Keywords: COPD; DAMPs; danger signals; cell death; pattern recognition receptors; RAGE; HMGB1; necroptosis; biomarkers; toll-like receptors
Dental Pulp Stem Cells in Human Disease
edited by Esther Wolfs, Tim Vangansewinkel and
submission deadline 25 May 2024 | Viewed by 172 | Submission Open
Keywords: dental pulp stem cells; disease; regenerative medicine; disease modeling
(This special issue belongs to the Section Stem Cells)
Advances in the Study of Natural Killer (NK) Cells
edited by Fuguo Liu, Mubin Tarannum and Yingjie Zhao
submission deadline 30 May 2024 | 1 articles | Viewed by 2529 | Submission Open
Keywords: natural killer cells; chimeric antigen receptor; immunotherapy; activating receptors; inhibitory receptors
(This special issue belongs to the Section Cellular Immunology)
Melanoma: From Molecular Mechanisms to Therapeutic Opportunities—Series 2 submission deadline 30 May 2024 | 2 articles | Viewed by 1374 | Submission Open
Keywords: melanomagenesis; treatment response; signal transduction; melanoma initiating cells; drug resistance; invasiveness; immune evasion; metastasis; MAPK pathway; PI3K/AKT survival pathways; MEKi; BRAFi; trametinib; dabrafenib; immunotherapies
(This special issue belongs to the Section Cellular Pathology)
Metabolic Regulation of Hematopoietic Stem Cells
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 878 | Submission Open
Keywords: hematopoietic stem cells; metabolic regulation; mitochondrial function; self-renewal and differentiation; quiescence; energy metabolism; HSC exhaustion; aging; bm niche; leukemia stem cells (LSCs)
(This special issue belongs to the Section Stem Cells)
CRISPR/Cas9-Mediated Gene Therapy in Cancer
edited by , Subhajit Giri and Sharad Awasthi
submission deadline 30 May 2024 | Viewed by 590 | Submission Open
Keywords: CRISPR/Cas; liquid tumor; solid-state cancer; gene therapy; AAV; CAR-T; lipid nanoparticle; immunotherapy; cytotoxicity
(This special issue belongs to the Section Cell Methods)
The Role of Histological Techniques in Neuroscience and Neural Engineering
edited by and Fernando Campos Sánchez
submission deadline 30 May 2024 | Viewed by 169 | Submission Open
Keywords: nerve tissue histology; histochemistry; immunohistochemistry; metal reduction techniques; light & electron microscopy; morphometric analyses; tissue engineering; nerve regeneration; neural degeneration; demyelinating diseases
(This special issue belongs to the Section Tissues and Organs)
Role of Innate Immunity in Chronic Kidney Diseases—Series 2
edited by
submission deadline 30 May 2024 | Viewed by 118 | Submission Open
Keywords: CKD; glomeruli; tubules; sterile inflammation; innate immunity; pattern recognition receptors (PRRs); damage-associated molecular patterns (DAMPs); STING; toll-like receptors; RIG-I; NLRP
(This special issue belongs to the Section Cellular Immunology)
Signaling Pathways in Pregnancy submission deadline 31 May 2024 | 12 articles | Viewed by 23240 | Submission Open
Keywords: cell signaling; proliferation; differentiation; invasion; placentation; placenta; trophoblast; preeclampsia; fetal growth restriction; gestational diabetes mellitus
(This special issue belongs to the Section Cell Signaling)
Advances in Muscle Research in Health and Disease
edited by
submission deadline 31 May 2024 | 5 articles | Viewed by 7884 | Submission Open
Keywords: skeletal muscle; cardiac muscle; smooth muscle; myocyte; vascular smooth muscle cell; stem cell; development; homeostasis; regeneration; biomarker; therapeutic target
(This special issue belongs to the Section Cell Signaling)
Autophagy and Apoptosis in Skeletal Muscle submission deadline 31 May 2024 | 2 articles | Viewed by 4941 | Submission Open
Keywords: autophagy; apoptosis; skeletal muscle; cell signaling; mitochondria; myopathies; sarcopenia; atrophy; immune system; therapeutic strategies
(This special issue belongs to the Section Autophagy)
Cellular Reprogramming during Sepsis and Potential Therapeutic Targets submission deadline 31 May 2024 | 2 articles | Viewed by 4559 | Submission Open
(This special issue belongs to the Section Cellular Pathology)
Muscle Homeostasis and Regeneration: From Molecular Mechanisms to Therapeutic Opportunities—Series II submission deadline 31 May 2024 | 3 articles | Viewed by 4271 | Submission Open
Keywords: muscle homeostasis; muscle regeneration; satellite cells; stem cells; FAPs; tissue niche; growth factors; inflammatory response; muscle pathology; aging
(This special issue belongs to the Section Cellular Pathology)
Cellular and Molecular Mechanisms Underlying Large-Vessel Vasculitis
edited by and Francesco Muratore
submission deadline 31 May 2024 | 3 articles | Viewed by 3865 | Submission Open
Keywords: large-vessel vasculitis; giant cell arteritis; Takayasu’ s arteritis; Behcet’ s Disease; in vitro/animal models; novel therapy
(This special issue belongs to the Section Cells of the Cardiovascular System)
The Applications of Flow Cytometry: Advances, Challenges, and Trends
edited by
submission deadline 31 May 2024 | 1 articles | Viewed by 3796 | Submission Open
Keywords: flow cytometry; single cell; cell function; T-cell subset
(This special issue belongs to the Section Cell Methods)
Molecular Signaling Pathways Associated with Neurotoxicity submission deadline 31 May 2024 | 2 articles | Viewed by 3193 | Submission Open
Keywords: neurotoxicity; signal transduction; heavy metals; environmental toxicants; neurodegeneration
(This special issue belongs to the Section Cells of the Nervous System)
The Current Applications and Potential of Stem Cell-Derived Organoids submission deadline 31 May 2024 | 2 articles | Viewed by 2766 | Submission Open
Keywords: organoids; stem cell-derived organoids; stem cells; pluripotent stem cells; iPSCs; organ-on-a-chip; disease modelling; cellular therapeutics; regenerative medicine
(This special issue belongs to the Section Stem Cells)
Viruses and Cancer: From Cellular Mechanism to Therapeutic Aspects submission deadline 31 May 2024 | 1 articles | Viewed by 2577 | Submission Open
Keywords: virus-induced cancer; host stress responses; DNA damage response; virus– host interactions; autophagy; cellular innate immunity; cell metabolism; immune evasion mechanisms; inflammation; therapeutic approach
(This special issue belongs to the Section Cellular Pathology)
Cell Biology: State-of-the-Art and Perspectives in China
edited by Di Chen and
submission deadline 31 May 2024 | 1 articles | Viewed by 2543 | Submission Open
MicroRNA as Biomarker in Carcinoma Cell
edited by , and Eduardo López-Urrutia
submission deadline 31 May 2024 | 1 articles | Viewed by 2259 | Submission Open
Keywords: carcinoma cell; microRNA; prognosis; diagnoses; molecular biomarker; methods for detection; miRNA targets
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Regulatory Programs of Skeletal Muscle Repair and Regeneration submission deadline 31 May 2024 | 1 articles | Viewed by 1657 | Submission Open
Molecular and Cellular Mechanisms of Cardiovascular and Metabolic Diseases
edited by
submission deadline 31 May 2024 | 1 articles | Viewed by 1655 | Submission Open
Keywords: mitochondrial dysfunction; endoplasmic reticulum (ER) stress; oxidative/nitrosative stress; diabetes; obesity; diet; atherosclerosis; hypertension; metabolomics; cell death; nutraceuticals/functional foods
(This special issue belongs to the Section Cells of the Cardiovascular System)
Effects of Microglia Changes on Neuroinflammation and Neurodegeneration
edited by Chi-Su Yoon and
submission deadline 31 May 2024 | 1 articles | Viewed by 1649 | Submission Open
Keywords: microglia; neuroinflammation; neurodegenerative disease; neurodegeneration; central nervous system
Research on Proteomics and Its Applications in Disease
edited by
submission deadline 31 May 2024 | 1 articles | Viewed by 1601 | Submission Open
Keywords: bottom-up proteomics; top-down proteomics; spatial proteomics; bioinformatics; human diseases; cancer; viral infections; bacterial infections; rare pathologies
(This special issue belongs to the Section Cell Methods)
The Pathogenetic Triad of Chronic Airway Diseases—Inflammation, Tissue Destruction, and Airway Remodeling
edited by and Michael Wegmann
submission deadline 31 May 2024 | 1 articles | Viewed by 1291 | Submission Open
Keywords: chronic lung disease; inflammation; signaling pathway; disease models; tissue destruction; airway remodeling; epigenetics
(This special issue belongs to the Section Cellular Immunology)
Highlights in Red Blood Cell Research submission deadline 31 May 2024 | 1 articles | Viewed by 1032 | Submission Open
Keywords: red blood cells; anemia; transfusion; erythropoiesis; signaling
Cancer Stem Cells and Immunotherapy submission deadline 31 May 2024 | Viewed by 621 | Submission Open
Keywords: cancer stem cells; CSC-specific biomarkers; immunotherapies; signaling transduction pathways; tumor microenvironment; metastasis; therapy resistance; DNA repair; cellular metabolism; combination therapies
(This special issue belongs to the Section Cellular Immunology)
Molecular Mechanisms Involved in Musculoskeletal and Other Tissue Injuries and Disruptions—Regenerative Potential of Exercise submission deadline 31 May 2024 | Viewed by 457 | Submission Open
Keywords: tissue injury; tissue regeneration; growth factors; inflammation; oxidative stress; metabolic stress; myokines; adipokines; neurokines; hypertrophy; biochemical pathways; skeletal muscles; liver/hepatic regeneration; brain/neuroplasticity; adipose tissue; varia
Organelle Contact and Its Physiological Implications submission deadline 31 May 2024 | Viewed by 261 | Submission Open
Keywords: inter-organelle communication; membrane contact sites; organelle dynamics; mitochondria-associated membranes; cellular homeostasis
Cellular and Molecular Alterations in the Down Syndrome Brain: A Starting Point for the Design of Therapeutic Approaches submission deadline 31 May 2024 | Viewed by 240 | Submission Open
Keywords: down syndrome; cellular defects; deranged molecular pathways; altered neurodevelopment; neurodegeneration; effects of therapies
(This special issue belongs to the Section Cellular Pathology)
Organogenesis and Regeneration: From Basic Research to Medical Study submission deadline 31 May 2024 | Viewed by 225 | Submission Open
Keywords: organogenesis; regeneration; development; proliferation; differentiation; blastema; signaling pathway
The Role of Apoptosis in Tissue Homeostasis, Malignancies, and Disease Pathogenesis submission deadline 31 May 2024 | Viewed by 211 | Submission Open
Keywords: apoptosis; cell death; p53 pathway; autophagy; caspase; mitochondria; neurodegeneration; inflammation; drug discovery; cancer; targeted anticancer therapy; autoimmunity; nanodelivery
(This special issue belongs to the Section Autophagy)
Mitochondria Meets Oxidative Stress submission deadline 31 May 2024 | Viewed by 203 | Submission Open
Keywords: mitochondria; oxidative stress; reactive oxygen species (ROS); cellular respiration; antioxidant defense; ageing
(This special issue belongs to the Section Mitochondria)
Synapses: Molecular Organization, Regulation and Synaptic Function
edited by Houhui Xia
submission deadline 31 May 2024 | Viewed by 186 | Submission Open
Keywords: synapse; glutamate; GABA; neurotransmitter receptor; scaffolding protein; ion channel; kinase; phosphatase; cell adhesion molecule
Radiation-Induced Brain Injury: Molecular Mechanisms and Therapeutic Strategies
edited by
submission deadline 31 May 2024 | Viewed by 167 | Submission Open
Keywords: radiation injury; brain; neurological and neuropsychiatric disorders; molecular mechanisms; novel therapeutic approaches
(This special issue belongs to the Section Cells of the Nervous System)
Pathophysiological Mechanisms of Cholestatic and Metabolic-Associated Fatty Liver Disease
edited by
submission deadline 31 May 2024 | Viewed by 152 | Submission Open
Keywords: steatosis; steatohepatitis; bile flux; inflammation; FXR
(This special issue belongs to the Section Cellular Pathology)
Pain: Neurobiology, Pathophysiology, and Therapeutic Approaches
edited by Joshua W. Little
submission deadline 31 May 2024 | Viewed by 152 | Submission Open
Keywords: pain; pain pathophysiology; neurobiology; nonopioid therapy; acute pain; chronic pain
(This special issue belongs to the Section Cellular Pathology)
Gene Editing in Stem Cells: Next-Generation Stem Cell Therapies
edited by
submission deadline 31 May 2024 | Viewed by 150 | Submission Open
Keywords: gene editing; stem cells; CRISPR/Cas system; ZFN; TALEN
(This special issue belongs to the Section Stem Cells)
T-Cell Acute Lymphoblastic Leukaemia submission deadline 31 May 2024 | Viewed by 145 | Submission Open
Keywords: T-cell leukemias; molecular pathogenesis; immune phenotype; T-cell leukemia epidemiology; T-cell ontogeny; transplantation in T-cell leukemia; target therapies
(This special issue belongs to the Section Cellular Immunology)
Role of Hyaluronan in Human Health and Disease
edited by Barbara Triggs-Raine and
submission deadline 31 May 2024 | Viewed by 136 | Submission Open
Keywords: hyaluronan; hyaluronidases; hyaluronan-binding proteins; hyaluronan receptors; fibrosis; cancer; development; immune function
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