Advances in Cardiometabolic Pathophysiology and Treatment
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Metabolism".
Deadline for manuscript submissions: 30 September 2026 | Viewed by 5
Special Issue Editors
Interests: cardiovascular disease; metabolic diseases; obesity; adipose tissue dysfunction; dyslipidemias; atherosclerosis; nutraceuticals; nutrition; biomarkers
Special Issues, Collections and Topics in MDPI journals
Interests: metabolic diseases; diabetes; pancreas; islet of Langerhans; beta-cells; molecular mechanisms of disease; cholesterol metabolism; neurodegenerative diseases; glia-neuron interactions
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The global prevalence of conditions such as type 2 diabetes mellitus, obesity, atherosclerosis, and heart failure requires a thorough understanding of their inter-related pathogenesis to enable effective therapies. For this Special Issue, we invite submissions of original experimental research articles and reviews, focusing on the intricate molecular and cellular mechanisms underlying the development and progression of cardio-metabolic diseases and their bidirectional interplay. We are particularly interested in manuscripts addressing the following areas of research:
- Molecular and cellular mechanisms linking pancreatic dysfunction and insulin resistance to endothelial dysfunction and myocardial pathology;
- The role of circulating factors such as adipokines and gut microbiome products in the initiation and progression of cardio-metabolic disease;
- Immunological and inflammatory pathological features of metabolic diseases;
- Identification and validation of novel diagnostic and prognostic biomarkers for early disease detection, risk stratification, and monitoring of therapeutic response;
- Evaluation of the cellular impact of novel or existing therapeutic strategies offering synergistic benefits to metabolic and cardiovascular systems (e.g., SGLT2 inhibitors and GLP-1R and/or GIPR agonists).
The end goal of this Special Issue is to identify and functionally characterize novel molecular targets, including proteins, non-coding RNAs and regulatory metabolites, that hold significant therapeutic promise. Submissions must be mechanism-focused and bridge the gap between basic molecular discoveries and preclinical target validation, advancing our understanding of the Cardiometabolic Syndrome framework.
Dr. Paolo Magni
Dr. Carla Perego
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- insulin resistance
- immunometabolism
- low-grade chronic inflammation
- cardiovascular diseases
- obesity
- type 2 diabetes mellitus
- adipose/adipocyte dysfunction
- dyslipidemia
- atherosclerosis
- metabolic-associated steatotic liver disease
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