Cellular and Molecular Mechanisms of Alcohol-Induced Cellular/Organ Injury and Regeneration
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 31 March 2026 | Viewed by 27
Special Issue Editor
Special Issue Information
Dear Colleagues,
This Special Issue focuses on the cellular and molecular mechanisms underlying alcohol-induced injury and regeneration in various organs. Chronic and acute alcohol exposure can trigger complex biochemical and cellular responses, leading to inflammation, oxidative stress, mitochondrial dysfunction, and tissue remodeling across multiple organ systems, including the liver, pancreas, lung, brain, and gut. This Special Issue welcomes original research and review articles that explore mechanisms of alcohol-induced cellular damage, tissue-specific responses, stem cell activation, immune modulation, and regenerative processes. Studies employing in vitro models, animal systems, and human tissues, particularly those integrating multi-omics, imaging, and molecular biology techniques, are encouraged. Contributions that shed light on potential therapeutic targets or strategies for mitigating alcohol-related pathologies and enhance tissue repair are especially welcome. By deepening our understanding of alcohol’s impact at the cellular level, this Special Issue will advance translational insights into alcohol-related diseases.
Dr. Mukund Srinivasan
Guest Editor
Manuscript Submission Information
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Keywords
- alcohol use disorder
- ethanol
- liver
- lung
- pancreas
- gut
- brain
- cellular toxicity
- alcohol metabolism
- alcohol metabolites
- oxidative stress
- mitochondrial stress
- ER stress
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