Targeting Tumor Microenvironments for Enhanced Cancer Immunotherapy
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cell Microenvironment".
Deadline for manuscript submissions: 30 September 2026 | Viewed by 8959
Special Issue Editor
Special Issue Information
Dear Colleagues,
Over the last decade, our understanding of the tumor microenvironment (TME) has expanded remarkably, revealing a complex network of cancer cells, immune cells, stromal components, and signaling factors that collectively shape tumor progression and therapeutic outcomes. Despite significant progress, numerous aspects of how the TME contributes to immune evasion and treatment resistance remain to be fully clarified. Addressing these gaps is crucial in refining current immunotherapies and discovering novel interventions that can transform cancer care.
For this Special Issue, I invite you to submit an original research article or review exploring facets of the TME and its impact on cancer immunotherapy. We welcome expert contributions covering mechanistic insights into immune modulation, strategies for reshaping the TME, biomarker discovery, and innovative combination therapies. Your valuable work will help us unlock new frontiers in TME research and ultimately improve patient outcomes. I look forward to your contributions and the exciting discussions that they inspire.
Dr. Xin Lu
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- tumor microenvironment
- cancer immunotherapy
- immune modulation
- immunosuppressive mechanisms
- combination therapies
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
