Parkinson's Disease: Advances in Molecular Understanding and Emerging Therapies
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Aging".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 104
Special Issue Editors
Interests: neurodegenerative diseases; translational neurobiology; disease models
Special Issue Information
Dear Colleagues,
With recent technical and scientific advances, we are witnessing a transformation in our understanding of the pathogenesis of Parkinson’s disease and related movement disorders. The recognition of prodromal non-motor symptoms and subtypes within motor presentation—including atypical Parkinsonism—is shaping not only clinical research but also novel efforts in model development for these diseases. Moreover, the application of advanced omics methodologies has provided novel insights into molecular and cellular phenotypes, which otherwise have remained inexplicable. Our collective hope is that these new model systems will guide translational research into disease modification and aid the discovery of novel mechanism-based therapies.
The present Cells Special Issue aims to synthesize recent advancements in disease models, cellular pathology, molecular phenotypes and bioassays that are shaping a refined understanding of PD and hold promise for transforming the field. Therefore, we invite researchers to present their scientific contributions in the form of original research articles and expert reviews highlighting recent advancements and/or controversies in PD research. We enthusiastically look forward to receiving your manuscripts.
Dr. Asad Jan
Dr. Sara Elfarrash
Guest Editors
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Keywords
- Parkinson’s disease
- atypical Parkinsonism
- neurodegeneration
- neuroinflammation
- alpha-synuclein
- disease models
- brain organoids
- human induced pluripotent stem cells (iPSCs)
- transcriptomics
- proteomics
- multi-omics
- spatial biology
- multiplex imaging
- PD genetics
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