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Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancements in Cardiac Metabolism

edited by

Michael Dodd

submission deadline 30 Apr 2026 | 2 articles | Viewed by 888 | Submission Open

Keywords: cardiovascular disease; metabolism; fatty acids; heart failure; mitochondrial dysfunction

(This special issue belongs to the Section Cells of the Cardiovascular System)

Immune Cells from Pluripotent Stem Cells

edited by

Eunju Kang

submission deadline 30 Apr 2026 | Viewed by 371 | Submission Open

Keywords: pluripotent stem cells; T cells; B cells; macrophages; natural killer (NK) cells; dendritic cells; megakaryocytes; platelets

(This special issue belongs to the Section Stem Cells)

Role of Gamma Delta T Cells in Immunotherapy

edited by

Dieter Kabelitz

and Wenwei Tu

submission deadline 30 Apr 2026 | Viewed by 348 | Submission Open

Keywords: gamma delta T cells; adoptive cell therapy; chimeric antigen receptors; bispecific antibodies; cancer immunotherapy; tumor microenvironment; phosphoantigens; butyrophilin 2A1/3A1; virus infection; multidrug-resistant bacteria; extracellular vesicles

(This special issue belongs to the Section Cellular Immunology)

Synaptic Dysregulation in Nervous System Disorders

edited by Pragya Goel

submission deadline 30 Apr 2026 | Viewed by 284 | Submission Open

Keywords: synapses; synaptic transmission; synaptic plasticity; neurodegeneration; neuropsychiatric disorders; neurodevelopmental diseases

(This special issue belongs to the Section Cells of the Nervous System)

Interleukin-1 Signaling in Cancer: Novel Mechanisms and Therapeutic Opportunities

edited by Afshan Fathima Nawas and

Jaehong Kim

submission deadline 30 Apr 2026 | Viewed by 77 | Submission Open

Keywords: interleukin-1 signaling; tumor microenvironment; inflammatory pathways; cytokine networks; cancer cell proliferation; epigenetic regulation in cancer; non-coding RNAs; immune modulation; cancer metabolism

Advances in Liquid Biopsy for Early Detection and Monitoring of Cancer

edited by Nicola Normanno,

Paola Ulivi

and

Tania Rossi

submission deadline 30 Apr 2026 | Viewed by 34 | Submission Open

Keywords: ctDNA; circulating tumor cells; microRNAs; exosomes; methylation; fragmentomics; early detection; minimal residual disease; artificial intelligence

Retinal Disorders: Cellular Mechanisms and Targeted Therapies

edited by

Takeshi Iwata

submission deadline 15 May 2026 | 4 articles | Viewed by 6442 | Submission Open

Keywords: inherited eye diseases; genome; omics; gene editing; iPS cells; animal models; single cell analysis; AI; epigenetics

(This special issue belongs to the Section Cellular Pathology)

Molecular and Translational Advances in Metastatic Breast Cancer Research

edited by

Sravani Ramisetty

submission deadline 15 May 2026 | Viewed by 31 | Submission Open

Keywords: metastatic breast cancer; tumor microenvironment; therapeutic resistance; immunotherapy; targeted therapy; cancer biomarkers; personalized medicine; translational oncology; circulating tumor cells; molecular mechanisms of metastasis

Basic Mechanisms and Emerging Therapeutic Strategies for Spinal Cord Injury

edited by

Daniel J. Hellenbrand

and Angela R. Filous

submission deadline 25 May 2026 | Viewed by 27 | Submission Open

Keywords: spinal cord injury; neuroinflammation; neural regeneration; axon growth; neurons; glial cells; oligodendrocytes; myelin; astrocytes; microglia

Proteomic Applications in Ageing and Neurodegenerative Conditions

edited by

Thomas Wishart

Rachel A. Kline

and

Dominic Kurian

submission deadline 31 May 2026 | 4 articles | Viewed by 17291 | Submission Open

(This special issue belongs to the Section Cell Methods)

Cellular and Molecular Basis of Brain Tumor

edited by

Wojciech Czyżewski

, Tomasz S. Mandat and Grzegorz Turek

submission deadline 31 May 2026 | Viewed by 82 | Submission Open

Keywords: brain tumor; glioma; tumor microenvironment; molecular oncology; epigenetics; tumor stem cells; biomarkers; therapeutic resistance; non-coding RNA; translational research

(This special issue belongs to the Section Cellular Pathology)

Sex Differences in Cardiovascular Structure and Function—From Mechanisms to Therapeutics

edited by

Roshanak Rahimian

and

Mitra Esfandiarei

submission deadline 31 May 2026 | Viewed by 53 | Submission Open

Keywords: cardiovascular diseases; sex hormones; sex differences; vascular and cell signaling; therapeutic targets

Development and Characterization of Innovative In Vitro Models

edited by Fengyan Deng and Chongbei Zhao

submission deadline 31 May 2026 | Viewed by 36 | Submission Open

Keywords: 3D organoid development; iPSC; iPSC reprogramming; primary cell derivation; cell immortalization; disease model development; stem cell therapy; molecular biology; cell signaling

Molecular Mechanisms of Fibrosis in Chronic Liver Diseases

edited by

Ahmad Salhab

, Regina Golan-Gerstl and Ihab Ansari

submission deadline 1 Jun 2026 | Viewed by 97 | Submission Open

Keywords: liver fibrosis; MASH; immune checkpoints; epigenetic regulation; hepatic stellate cells (HSCs); antifibrotic therapy; molecular mechanisms; inflammation; ROS

Novel Insights into Developing Therapeutic Strategies for Neurological Disorders

edited by

Hui Jin Shin

, Joanna A. Korecka and

Yu-Han Huang

submission deadline 15 Jun 2026 | Viewed by 61 | Submission Open

Keywords: neurological disorders; RNA therapeutics; gene therapy; antisense oligonucleotides; gene editing; cell therapy; precision medicine; neurodegenerative diseases; neurodevelopmental disorders; neurogenetic disorders

Mechanisms of Antimicrobial Treatment in Human Diseases

edited by

Paolo Gaibani

submission deadline 20 Jun 2026 | 1 articles | Viewed by 2458 | Submission Open

Keywords: multidrug resistance; epidemiology; novel antimicrobial resistance traits

(This special issue belongs to the Section Cellular Pathology)

The Orchestration of Glial Cells in Health and Disease

edited by Keying Zhu

submission deadline 25 Jun 2026 | Viewed by 118 | Submission Open

Keywords: microglia; oligodendrocytes; astrocytes; myelin; neuroinflammation

Diabetes-Induced Organ Damage: Cellular Mechanisms and Therapeutic Opportunities

edited by

Mohammed S. Razzaque

submission deadline 30 Jun 2026 | 6 articles | Viewed by 21682 | Submission Open

Keywords: diabetes mellitus; vascular lesions; nephropathy; cardiomyopathy; neuropathy; retinopathy; therapeutic opportunities

(This special issue belongs to the Section Tissues and Organs)

Emerging Topics in Cachexia

edited by Gabriela Salim Ferreira De Castro

submission deadline 30 Jun 2026 | 1 articles | Viewed by 648 | Submission Open

Keywords: cachexia; skeletal muscle loss; adipose tissue loss; inflammation; sarcopenia; cancer; body composition; biomarkers

Retinoic Acid and Retinoid X Receptors - Series II

edited by

Michael Schubert

and

Pierre Germain

submission deadline 30 Jun 2026 | Viewed by 429 | Submission Open

Keywords: nuclear receptor signaling; retinoic acid receptor; retinoid X receptor; pharmacology; structure/function relationships; genomic and non-genomic signaling; post-translational modification; homeostasis and disease; development; origin and evolution

(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)

MicroRNAs: Regulators of Cellular Fate

edited by

Hsiuying Wang

submission deadline 30 Jun 2026 | Viewed by 186 | Submission Open

Keywords: microRNA targets; microRNA conservation; microRNA pathway; microRNA mimics; microRNA antagonist; disease biomarker

The Role of PPARs in Disease - Volume IV

edited by

Kay-Dietrich Wagner

and

Nicole Wagner

submission deadline 30 Jun 2026 | Viewed by 65 | Submission Open

Keywords: PPAR; immune function; liver; adipose tissue; cardiovascular system; muscle; brain; neurological disease; psychiatric diseases; cancer; transcriptional regulation; ligands; agonists/antagonists

(This special issue belongs to the Section Cells of the Cardiovascular System)

Biochemical Interaction and Supramolecular Complexes of Receptors in Cell Membranes

edited by

Michela Corsini

and

Stefania Mitola

submission deadline 8 Jul 2026 | Viewed by 540 | Submission Open

Keywords: membrane receptors; molecular complex; membrane microdomains

Role of Hippo Signaling in Cancer

edited by

Dimpi Mukhopadhyay

and

Alessio D'Alessio

submission deadline 15 Jul 2026 | Viewed by 2 | Submission Open

Keywords: angiogenesis; cancer metabolism; cancer stemness; chemoresistance; endothelial cell plasticity; epithelial-to-mesenchymal transition (EMT); hippo signaling pathway; immunotherapy; mechanotransduction; targeted cancer therapy; TEAD transcription factors; therapeutic resistance; tumor microenvironment; tumorigenesis; YAP/TAZ; new therapeutic modalities to target YAP/TAZ-driven tumors including ferroptosis

(This special issue belongs to the Section Cell Signaling)

Novel Molecular Targets for the Treatment of Sleep Disorders

edited by

Dae-Wui Yoon

submission deadline 25 Jul 2026 | Viewed by 192 | Submission Open

Keywords: sleep disorders; molecular targets; glymphatic system; neuroinflammation; circadian rhythms; microbiome; biomarkers; pharmacological therapy; gene therapy; neurodegeneration

Study on Ovarian Follicle Development

edited by Cecily V. Bishop and Jessica Cristina Lemos Motta

submission deadline 10 Aug 2026 | Viewed by 55 | Submission Open

Keywords: follicular development; ovarian follicle activation; ovarian reserve; in vitro follicle culture; translational reproductive biology

Cellular and Molecular Mechanisms of Abiotic Stress Tolerance in Plants

edited by Aziz Khan and

Xin Zhang

submission deadline 25 Aug 2026 | 2 articles | Viewed by 5587 | Submission Open

Keywords: abiotic stress; molecular mechanism; gene expression; cellular adaptation; signal transduction; plant physiology; molecular pathway; stress resilience; crop productivity; agronomic performance

(This special issue belongs to the Section Plant, Algae and Fungi Cell Biology)

Current Status and Future Challenges of Liquid Biopsy—2nd Edition

edited by

Kenichi Suda

and

Shuta Ohara

submission deadline 31 Dec 2027 | Viewed by 36 | Submission Open

Keywords: minimal residual disease (MRD); ctDNA; cfDNA; heterogeneity; comprehensive genomic profiling; biomarker; diagnosis; personalization; prognostic marker

Displaying special issue 551-600 on page 12 of 12.

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