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Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Cellular and Molecular Treatment of Autoimmune Diseases

edited by

Panagiotis Athanassiou

Dimitrios P. Bogdanos

and

Ifigenia Kostoglou-Athanassiou

submission deadline 30 Sep 2024 | 6 articles | Viewed by 14719 | Submission Open

Keywords: autoimmune diseases; disease activity; TNFa inhibitors; tocilizumab; infliximab; golimumab; etanercept; JAK inhibitors; cellular targets; molecular targets

(This special issue belongs to the Section Cellular Immunology)

Genetics and Pathomechanisms of Amyotrophic Lateral Sclerosis (ALS)

edited by

Smita Saxena

submission deadline 30 Sep 2024 | 8 articles | Viewed by 14460 | Submission Open

Keywords: genetics of ALS/FTD; ER stress and UPR; mitochondria and mitochondrial-associated membranes; Ca2+ signaling; excitotoxicity/neuronal networks; synaptic dysfunction; therapeutic strategies

(This special issue belongs to the Section Cellular Pathology)

Mechanism of Cell Signaling during Eye Development and Diseases

edited by

Mehrnoosh Saghizadeh Ghiam

and

Vivien Coulson-Thomas

submission deadline 30 Sep 2024 | 8 articles | Viewed by 13540 | Submission Open

Keywords: cell signaling; ocular; eye disorders; Wnt signaling; TGF-β

(This special issue belongs to the Section Cell Signaling)

Novel Therapeutic Targets and Approaches, Genetic Markers and Signaling Pathways in Neoplasms

edited by

Daria A. Chudakova

and

Kazuyuki Kitatani

submission deadline 30 Sep 2024 | 5 articles | Viewed by 8873 | Submission Open

Keywords: cancer; neoplasms; personalized medicine; genetic markers; next-generation sequencing (NGS); whole-genome sequencing; signaling pathways in cancer; novel therapeutic targets; drug development

(This special issue belongs to the Section Cell and Gene Therapy)

Understanding Spinal Cord Injury and Repair: From Molecules to Neurocircuits and Multimodal Prostheses

edited by

Yang D. Teng

submission deadline 30 Sep 2024 | 6 articles | Viewed by 8224 | Submission Open

(This special issue belongs to the Section Cells of the Nervous System)

Cancer-Related Signaling Cascades: Current Knowledge and Potential Therapeutic Targets

edited by

Takatsune Shimizu

and

Hideyuki Takeshima

submission deadline 30 Sep 2024 | 5 articles | Viewed by 7258 | Submission Open

Keywords: cancer signaling; crosstalk of signaling pathway; oncogenic activation; genetic alterations; epigenetic alterations; tumor microenvironment; therapeutic resistance

(This special issue belongs to the Section Cellular Pathology)

New Advances and Perspectives in Nanotechnology for the Treatment of Cancer Cells

edited by

Karuppusamy Shanmugapriya

submission deadline 30 Sep 2024 | 4 articles | Viewed by 6408 | Submission Open

Keywords: nanotechnology; immunotherapeutics; cancer biotherapeutics; proliferation; regulating factors; cell culture; biomedical application; nutraceuticals; cancer treatment

(This special issue belongs to the Section Cell Methods)

Stem and Progenitor Cells in Bone Regeneration

edited by

Sophie Verrier

submission deadline 30 Sep 2024 | 3 articles | Viewed by 5774 | Submission Open

Keywords: stem cells; progenitor cells; bone marrow stromal cells; bone healing and regeneration; tissue engineering; regenerative medicine; cells mobilization; intra-operative approaches; clinical use ethics/regulations burdens

(This special issue belongs to the Section Stem Cells)

Natural Products in Neurodegenerative Diseases: Current Trends and Future Perspectives

edited by

Anthony Tsarbopoulos

and Nikolaos Kokras

submission deadline 30 Sep 2024 | 2 articles | Viewed by 4425 | Submission Open

Keywords: bioactive compounds; protein aggregation processes in AD; cognitive; anxiolytic and antidepressant effects

(This special issue belongs to the Section Cells of the Nervous System)

Cell Biology: State-of-the-Art and Perspectives in Italy 2024

edited by

Vincenzo Carafa

submission deadline 30 Sep 2024 | 5 articles | Viewed by 3750 | Submission Open

Inflammatory Pathways in Psychiatric Disorders

edited by Teresa Femenía

submission deadline 30 Sep 2024 | 1 articles | Viewed by 3749 | Submission Open

Keywords: inflammation; immune system; psychiatry; emotion; cognition

(This special issue belongs to the Section Cells of the Nervous System)

Molecular Insights into Corneal Wound Healing and Inflammation

edited by Tomas Blanco

submission deadline 30 Sep 2024 | 2 articles | Viewed by 3701 | Submission Open

Keywords: corneal wound healing; corneal transplantation; sensory nerves; neovascularization; fibrosis; growth factors; cytokines; neuropeptides

(This special issue belongs to the Section Cellular Immunology)

Molecular and Clinical Indicators of Cancer Management: Perspective on Cellular Therapy and Precision Medicines

edited by

Rick Francis Thorne

and

Ihtisham Bukhari

submission deadline 30 Sep 2024 | 1 articles | Viewed by 3008 | Submission Open

Keywords: cancer management; immunotherapy; precision medicine; anticancer drugs; cancer biomarkers; cancer development

(This special issue belongs to the Section Cellular Metabolism)

Resistance of Hematological Malignancies to CAR T Cell Therapy

edited by

Ali R. Jazirehi

submission deadline 30 Sep 2024 | 1 articles | Viewed by 2413 | Submission Open

Keywords: NHL; ALL; CAR T cell; immunotherapy; resistance; apoptosis

Cell Biology for Boron Neutron Capture Therapy (BNCT)

edited by

Wolfgang Sauerwein

Mitsuko Masutani

Lucie Sancey

and John Hopewell

submission deadline 30 Sep 2024 | 1 articles | Viewed by 2385 | Submission Open

Keywords: boron neutron capture therapy (BNCT); radiation biology; radiation oncology; drug development; imaging; targeted therapies; boron chemistry

Microbe–Heavy Metal Interactions

edited by

Timothy E. Ford

submission deadline 30 Sep 2024 | 1 articles | Viewed by 2294 | Submission Open

Keywords: horizontal gene transfer (HGT); gene duplication; natural selection; mutation; heavy metal resistance genes (MRGs); antibiotic resistance genes (ARGs); acid mine drainage (AMD); heavy metals; plasmids; mobile genetic elements (MGEs); transposons; extreme environments; bioremediation

The Role of Natural Extracts and Phytochemicals in the Treatment of Chronic Diseases

edited by

Daniela Carlisi

and

Anna De Blasio

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1962 | Submission Open

The Mechanisms or Targets by Which the Microbiome Inhibits or Enhances Anti-inflammation or Tumor

edited by

Xiaonan Han

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1436 | Submission Open

Keywords: microbiome; IBD; colon cancer; colitis-associated cancer; Th17 cells; cytokines; immune tolerance

(This special issue belongs to the Section Cellular Pathology)

Advances in DNA Repair Disorders Research: Molecular Mechanisms, Novel Therapies and Implications for Understanding Aging, Neurological Dysfunction and Cancer Progression

edited by Manuela Lanzafame

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1361 | Submission Open

Keywords: DNA repair diseases; molecular mechanism; signaling pathway; therapies; aging; cancer; neurological dysfunction

(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)

New Concepts Relating Mesenchymal Tumors Based on Genetics and Epigenetics

edited by

Uta Flucke

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1274 | Submission Open

Keywords: mesenchymal tumors; soft tissue; sarcoma; genetics; epigenetics

(This special issue belongs to the Section Cell Microenvironment)

Neurodegeneration Research Models: Advantages and Limitations

edited by

Morten Meyer

and Rohit Kumar

submission deadline 30 Sep 2024 | Viewed by 441 | Submission Open

Keywords: in vitro/vivo neurodegenerative disease models; computational neurodegenerative disease models; synucleinopathies; tauopathies; neurodegenerative disorders; neurodegeneration

(This special issue belongs to the Section Cells of the Nervous System)

Hepatology: From Natural History to Therapeutics—Second Edition

edited by

Alessandra Mangia

submission deadline 30 Sep 2024 | Viewed by 403 | Submission Open

Keywords: HCV; HBV; cirrhosis; HCC

(This special issue belongs to the Section Cellular Pathology)

Cellular and Molecular Mechanisms of Cancer Metastasis—2nd Edition

edited by

Ira-Ida Skvortsova

submission deadline 30 Sep 2024 | Viewed by 379 | Submission Open

(This special issue belongs to the Section Cellular Pathology)

Altered Central and Peripheral Inflammation in Depression

edited by

Miloš Mitić

and

Tamara Lazarević-Pašti

submission deadline 30 Sep 2024 | Viewed by 318 | Submission Open

Keywords: depression; inflammation; comorbidity; disease; therapy; immunopsychiatry

(This special issue belongs to the Section Cells of the Nervous System)

Membrane Damage and Repair in Organelles

edited by Yoko Shiba

submission deadline 30 Sep 2024 | Viewed by 276 | Submission Open

Keywords: membrane damage; organelle; pathogen; inorganic material; galectin

(This special issue belongs to the Section Intracellular and Plasma Membranes)

Synaptic Dysfunction in the Progressive Neurodegeneration of Alzheimer’s Disease and Related Dementia

edited by

Balaji Krishnan

submission deadline 30 Sep 2024 | Viewed by 265 | Submission Open

Keywords: synapses; dendrites; neurons; astrocytes; microglia; autophagy; reactive oxygen species (ROS); amyloidogenic proteins (including Tau; Aβ ; TDP-43; α -synuclein); AD/ADRD; traumatic brain injury (TBI)

(This special issue belongs to the Section Cellular Immunology)

Multidimensional Impact of Ionic Liquids on Cellular Dynamics: Integrating Cell Physiology, Molecular Biology, and Biophysics

edited by Gagandeep Singh and Meena Bisht

submission deadline 30 Sep 2024 | Viewed by 256 | Submission Open

Keywords: ionic liquids; cellular dynamics; multidisciplinary research; biophysical effects; biotechnological applications

Recent Advances in Metabolism and Oxidative Stress in Human Diseases 2.0

edited by

Isabella Panfoli

and Vanessa Cossu

submission deadline 30 Sep 2024 | Viewed by 204 | Submission Open

Keywords: antioxidant responses; redox balance; ROS; hematologic oncology; solid tumors; immune response; ATP; cancer cells; mitochondria-ER interactions; endoplasmic reticulum; glucose metabolism; inflammation; mitochondria; mitochondrial dynamics; autophagy; mitophagy; metabolic plasticity; metabolism

(This special issue belongs to the Section Cellular Metabolism)

Skeletal Muscle Differentiation and Epigenetics - Volume II

edited by

Rossella Maione

submission deadline 30 Sep 2024 | Viewed by 197 | Submission Open

Keywords: skeletal muscle differentiation and regeneration; epigenetic control of gene expression; chromatin structure and architecture; DNA methylation; histone modifications; nucleosome remodeling; noncoding RNAs; muscle regulatory factors; signal transduction

(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)

Unveiling Axon-Glia Communication in Health and Disease

edited by

Michela Rigoni

and Samuele Negro

submission deadline 30 Sep 2024 | Viewed by 196 | Submission Open

Keywords: glia-axon communication; oligodendrocytes; astrocytes; microglia; Schwann cells; enteric glia; neurodevelopment; neurodegeneration; neuroregeneration; cancer; pain; aging

(This special issue belongs to the Section Cells of the Nervous System)

Recent Advances of Apoptosis and Autophagy in Cardiovascular Diseases and Cancer

edited by Howard Chen, Vicky K. Yang and Asma Boukhalfa

submission deadline 30 Sep 2024 | Viewed by 173 | Submission Open

Keywords: autophagy; apoptosis; cardiovascular disease; cancer; cardio-oncology; cardioprotection; circulating biomarkers; 3D culture; animal models; clinical translation; drug development; metabolism; inflammation; signaling pathways

(This special issue belongs to the Section Cells of the Cardiovascular System)

Updates on Mesenchymal Stem Cells-Derived Extracellular Vesicles: Second Edition

edited by

Carl Randall Harrell

submission deadline 30 Sep 2024 | Viewed by 161 | Submission Open

Keywords: MSC-Exo-based tissue repair and regeneration; MSC-Exo-based immunomodulation; MSC-Exo-dependent therapy of inflammatory diseases; MSC-Exo-based therapy of degenerative diseases

(This special issue belongs to the Section Stem Cells)

Ion Channels in Cancer: An Update

edited by

Michael X. Zhu

and

Yong Zhou

submission deadline 30 Sep 2024 | Viewed by 151 | Submission Open

Keywords: ion channels; cancer therapy; cancer cell biology; mitogenic signaling; cancer signaling

(This special issue belongs to the Section Cell Proliferation and Division)

The Role of Adipose-Derived Stem Cells in Neural Regeneration

edited by Silvan Maximilian Klein, Alexandra M. Anker and Oliver Heinrich Felthaus

submission deadline 30 Sep 2024 | Viewed by 148 | Submission Open

Keywords: neural regeneration; mesenchymal stem cells; peripheral nerve injury; regenerative medicine; growth factors; cytokines; exosomes

(This special issue belongs to the Section Stem Cells)

Small Molecular Therapeutics Promoting Neuronal Plasticity, Hippocampal Learning, and Memory

edited by

Avik Roy

submission deadline 30 Sep 2024 | Viewed by 147 | Submission Open

Keywords: synaptic transmission; dendritic spines; metabotropic calcium influx; dendritic morphogenesis; small molecular therapeutics promoting neuronal plasticity

(This special issue belongs to the Section Cells of the Nervous System)

Mitochondrial Function: From Physiology to Pathology

edited by

Andreas Till

submission deadline 30 Sep 2024 | Viewed by 118 | Submission Open

Keywords: mitochondria; organelle homeostasis; mitochondrial diseases; oxidative phosphorylation; electron transport chain; ROS; mitophagy; aging

(This special issue belongs to the Section Cellular Pathology)

The Role of Cilia in Health and Diseases

edited by Rim Hjeij

submission deadline 1 Oct 2024 | 8 articles | Viewed by 13766 | Submission Open

Keywords: motile cilia; motile ciliopathy; Primary ciliary dyskinesia; genetic screening; bronchiectasis; hydrocephalus; laterality defects; infertility; gene therapy

Allergic Airway Disease: Immunology, Pathogenesis, Inflammation

edited by

Luisa Ricciardi

submission deadline 1 Oct 2024 | 1 articles | Viewed by 1626 | Submission Open

(This special issue belongs to the Section Cellular Immunology)

Calcium Signaling in Immune Cells

edited by

Agnese Secondo

and

Stefania Loffredo

submission deadline 5 Oct 2024 | 2 articles | Viewed by 2599 | Submission Open

Keywords: calcium signaling; neurodegeneration; immunodeficiencies; cytokine; microglia; immune cells; SOCE; intracellular mediators; angiogenesis; organellar calcium

(This special issue belongs to the Section Cell Signaling)

The Hippo Signaling Pathway in Cell Biology

edited by

Daniel Bouvard

and Liu Mei

submission deadline 5 Oct 2024 | Viewed by 265 | Submission Open

Keywords: cell cycle; hippo pathway; cancer

(This special issue belongs to the Section Cell Signaling)

Protein Quality Control under Different Pathological Conditions

edited by Rajeshwary Ghosh

submission deadline 10 Oct 2024 | Viewed by 134 | Submission Open

Keywords: proteasome; autophagy; disease

(This special issue belongs to the Section Cellular Pathology)

Function and Dysfunction of the Caveolar Network in Cell Signaling and Human Disease: An Update after 70 Years of the Discovery of Caveolae

edited by

Alessio D'Alessio

submission deadline 14 Oct 2024 | 2 articles | Viewed by 3835 | Submission Open

Keywords: cancer; caveolae; caveolin; cavins; cell metabolism; endocytosis; hypertension; lipid homeostasis; lipid rafts; lipodystrophy; mechanobiology; caveolinopathies; muscular dystrophy

(This special issue belongs to the Section Cell Signaling)

Role of Vascular Smooth Muscle Cells in Cardiovascular Disease

edited by

Alejandra San Martin

and Claire Holden

submission deadline 15 Oct 2024 | 9 articles | Viewed by 21180 | Submission Open

Keywords: cardiovascular disease; vascular smooth muscle cell (VSMC); phenotypic modulation; VSMC migration; atherosclerosis; VSMC plasticity; vascular injury; foam cells; stroke; myocardial infarction; peripheral artery disease (PAD); restenosis; inflammation; metabolism

(This special issue belongs to the Section Cells of the Cardiovascular System)

Stroke Immunology: Mechanisms and Therapeutic Prospects

edited by Emmanuel Pinteaux and

Alba Grayston-Morales

submission deadline 15 Oct 2024 | 2 articles | Viewed by 3967 | Submission Open

Keywords: stroke; neuroimmunology; neuroinflammation; thromboinflammation; blood-brain barrier; glia; immunomodulation

(This special issue belongs to the Section Cellular Immunology)

Skeletal Muscle Atrophy in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities

edited by

Marco Vincenzo Narici

submission deadline 15 Oct 2024 | 1 articles | Viewed by 1654 | Submission Open

Keywords: muscle atrophy; inactivity; ageing; sarcopenia; neuromuscular disorders

(This special issue belongs to the Section Cellular Pathology)

Biology and Potential Medical Applications of Mesenchymal Stem Cell Exosomes

edited by George G. Koliakos

submission deadline 15 Oct 2024 | 1 articles | Viewed by 1325 | Submission Open

Keywords: mesenchymal stem cells; extracellular vesicles; exosomes; exosomes in drug delivery; intercellular signaling; diagnosis and therapy; exosome miRNA packaging and transfer; exosome isolation; characterization and analysis; molecular signals controlling exosome production and release

(This special issue belongs to the Section Stem Cells)

Biological Pathways and Molecular Mechanisms of Dementia—Second Edition

edited by

Wataru Araki

and

Madepalli K. Lakshmana

submission deadline 15 Oct 2024 | Viewed by 190 | Submission Open

Keywords: Alzheimer’ s disease; frontotemporal dementia; dementia with Lewy bodies; amyloid-β ; tau; TDP-43; FUS; α -synuclein; neurodegeneration; neuropathology; neuroinflammation

(This special issue belongs to the Section Cellular Aging)

Role of Inflammasome Activation in Innate and Adaptive Immunity

edited by

Juan Pablo de Rivero Vaccari

Robert W. Keane

and

W. Dalton Dietrich

submission deadline 20 Oct 2024 | 5 articles | Viewed by 8599 | Submission Open

Keywords: inflammasome; caspase-1; ASC specks; pyroptosis; innate immunity; adaptive immunity; sterile inflammation; cell death pathways; apoptosis; autophagy; NETosis; PANoptosis; ferroptosis; necroptosis; neurodegenerative disease; trauma; cerebral ischemia; biomarkers

(This special issue belongs to the Section Cellular Immunology)

Autophagy and Inflammasome

edited by

Nataša Kopitar Jerala

submission deadline 20 Oct 2024 | 1 articles | Viewed by 1745 | Submission Open

Keywords: autophagy; inflammasome; immune response inflammasome; mitochondrial ROS; myeloid cells; mTOR signaling

(This special issue belongs to the Section Autophagy)

Molecular Mechanisms of Autism Spectrum Disorder

edited by Tanya Gandhi and

Charles Lee

submission deadline 20 Oct 2024 | 1 articles | Viewed by 1268 | Submission Open

Keywords: autism spectrum disorder; neurodevelopmental disorders; molecular mechanisms; cellular-molecular mechanisms; neurobiological mechanisms; neural mechanisms; intervention approaches; treatment strategies

(This special issue belongs to the Section Cells of the Nervous System)

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