Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section
Search by Title/Keyword
 
Order results
Display
Results per page
Non-Coding and Coding RNAs in Targeted Cancer Therapy submission deadline 25 May 2026 | 4 articles | Viewed by 7837 | Submission Open
Keywords: gene expression; non-coding RNAs; lncRNAs; microRNAs; piwi-associated RNA; circular RNAs; therapeutic targets
(This special issue belongs to the Section Cell and Gene Therapy)
Small Molecular Therapeutics Promoting Neuronal Plasticity, Hippocampal Learning, and Memory
edited by
submission deadline 25 May 2026 | 2 articles | Viewed by 5124 | Submission Open
Keywords: synaptic transmission; dendritic spines; metabotropic calcium influx; dendritic morphogenesis; small molecular therapeutics promoting neuronal plasticity
(This special issue belongs to the Section Cellular Neuroscience)
Advances in Musculoskeletal Tissue Regeneration Using Mesenchymal Stromal/Stem Cells, Biomaterials, and Signaling Molecules: Second Edition submission deadline 25 May 2026 | 2 articles | Viewed by 3708 | Submission Open
Keywords: mesenchymal stromal/stem cells; extracellular vesicles; biomaterials; signalling molecules; microphysiological systems; musculoskeletal regeneration; immunomodulation; cell therapy; tissue engineering
(This special issue belongs to the Section Stem Cells)
Recent Advances in Astrocyte Neuron Communication submission deadline 25 May 2026 | Viewed by 991 | Submission Open
Keywords: astrocytes; calcium signaling; ion channels; gliotransmitters; brain circuits; reactive astrogliosis; astrocyte heterogeneity; astrocyte– neuron networks; synaptic plasticity
(This special issue belongs to the Section Cellular Neuroscience)
Cell Therapy for Retinal Diseases submission deadline 25 May 2026 | Viewed by 398 | Submission Open
Keywords: retinal diseases; cell therapy; stem cells; retinal regeneration; cell transplantation; gene editing in retinal therapy; tissue engineering; retinal organoids; vision restoration; clinical translation of cell therapy; future directions in retinal regeneration
(This special issue belongs to the Section Tissues and Organs)
Cell Signaling in Neurodegeneration Disease
edited by , Yasuhiro Funahashi, , and Md-nadim Hossain
submission deadline 25 May 2026 | Viewed by 304 | Submission Open
Keywords: neurodegeneration; cell signaling; biomarkers; synaptic dysfunction; neuroinflammation; protein aggregation; IPSC and animal models; mitochondrial dysfunction; therapeutic targets; translational neuroscience
(This special issue belongs to the Section Cellular Neuroscience)
Basic Mechanisms and Emerging Therapeutic Strategies for Spinal Cord Injury
edited by and Angela R. Filous
submission deadline 25 May 2026 | Viewed by 150 | Submission Open
Keywords: spinal cord injury; neuroinflammation; neural regeneration; axon growth; neurons; glial cells; oligodendrocytes; myelin; astrocytes; microglia
Metabolic Regulation of Cell Behavior and Implications for Aging
edited by and José Antonio Rodríguez Navarro
submission deadline 25 May 2026 | Viewed by 85 | Submission Open
Keywords: metabolism; cellular aging; senescence; proteostasis; oxidative stress; glycation; autophagy
Cellular and Molecular Insights into Female Reproductive Biology
edited by
submission deadline 25 May 2026 | Viewed by 80 | Submission Open
Keywords: female reproductive biology; cellular mechanisms; reproductive aging; microfluidics; fertility preservation; stem cells; uterine endocrinology; infertility; reproductive health; gametogenesis
(This special issue belongs to the Section Reproductive Cells and Development)
Resistance of Hematological Malignancies and Solid Tumors to CAR T Cell Therapy
edited by
submission deadline 25 May 2026 | Viewed by 53 | Submission Open
Keywords: solid tumors; hematological malignancies; CAR T cell; immunotherapy; resistance; apoptosis
Brain Function and Structure: Mapping Complexity in Neuronal Cells submission deadline 25 May 2026 | Viewed by 43 | Submission Open
Keywords: optogenetics; lab-on-chip platforms and brain organoids; neuronal and glial networks; neuromechanobiology; system neuroscience
Human DNA Replication/Repair Factors submission deadline 25 May 2026 | Viewed by 21 | Submission Open
Keywords: DNA replication; replisome; DNA polymerase; helicase; replication fork; DNA repair; replication stress; DNA damage response; homologous recombination; replication-coupled DNA repair
From Fat to Flame: Targeting Adipose Tissue in Chronic Inflammation and Exploring Therapeutic Strategies submission deadline 29 May 2026 | Viewed by 238 | Submission Open
Keywords: obesity; inflammasomes; immune system; microbiota
(This special issue belongs to the Section Tissues and Organs)
Therapeutic Targeting of Myeloid Cells in Tumor
edited by Mirko Farina and
submission deadline 30 May 2026 | Viewed by 47 | Submission Open
Keywords: myeloid cells; therapeutic targeting; tumor microenvironment; leukemia; myelodysplastic syndromes; tumor development
Autophagy in Stress Responses: From Molecular Mechanisms to Disease Relevance
edited by and Kleiton Silva
submission deadline 30 May 2026 | Viewed by 39 | Submission Open
Keywords: autophagy; stress response; proteostasis; mitophagy; neurodegeneration; aging; stress granules; mTOR signaling; selective autophagy; disease models; exercise; muscle disorders
(This special issue belongs to the Section Autophagy)
Perinatal Brain Injury—from Pathophysiology to Therapy
edited by Cora H.A. Nijboer, and
submission deadline 31 May 2026 | 9 articles | Viewed by 19909 | Submission Open
Keywords: preterm birth; perinatal brain injury; infection; inflammation; hypoxia; ischemia; hyperoxia; malnutrition; regenerative therapies; pharmacological intervention; stem cells
(This special issue belongs to the Section Cellular Neuroscience)
Proteomic Applications in Ageing and Neurodegenerative Conditions submission deadline 31 May 2026 | 4 articles | Viewed by 18891 | Submission Open
(This special issue belongs to the Section Cell Methods)
3D Cultures and Organ-on-a-Chip in Cell and Tissue Cultures submission deadline 31 May 2026 | 6 articles | Viewed by 13831 | Submission Open
Keywords: three-dimensional cell culture; organ-on-a-chip; tissue engineering; regenerative medicine; drug testing; microfluidics; in vitro models; personalized medicine; cellular interaction; disease modeling
(This special issue belongs to the Section Cell Methods)
Intervertebral Disc Degeneration and Regeneration: New Molecular Mechanisms and Therapeutics—Second Edition
edited by
submission deadline 31 May 2026 | 4 articles | Viewed by 12167 | Submission Open
Keywords: spine; intervertebral disc; biomaterial; stem cell; gene therapy
(This special issue belongs to the Section Cellular Pathology)
Cilia-Based New Discoveries: Ciliogenesis, Function, and Human Diseases submission deadline 31 May 2026 | 2 articles | Viewed by 5421 | Submission Open
Keywords: primary cilium; human disease; cell signaling; mTOR; Hedgehog; WNT; PDGFRalpha
Immunoregulatory Functions of Mesenchymal Stem Cells (MSCs)
edited by
submission deadline 31 May 2026 | 2 articles | Viewed by 5195 | Submission Open
Keywords: mesenchymal stem cells; MSCs; immunoregulation; immunosuppression
(This special issue belongs to the Section Stem Cells)
Glial Cells: Physiological and Pathological Perspective
edited by
submission deadline 31 May 2026 | 3 articles | Viewed by 3980 | Submission Open
Keywords: neurodegeneration; oligodendrocytes; astrocytes; microglia; neuroinflammation; demyelination neuron– glial interactions; homeostasis; glia-targeted therapies
(This special issue belongs to the Section Cellular Neuroscience)
Natural Killer (NK) Cells in Immunity: Limitations and Potential
edited by Rehan Mujeeb Faridi
submission deadline 31 May 2026 | 2 articles | Viewed by 3341 | Submission Open
Keywords: natural killer cells; adaptive NK cells; infection
(This special issue belongs to the Section Cellular Immunology)
Emerging Advances in Neurodegeneration: Innovations in Stem Cell and Organoid Research
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 2948 | Submission Open
Keywords: neurodegeneration; stem cells; induced pluripotent stem cells (iPSCs); brain organoids; disease modeling; therapeutic strategies; personalized medicine
(This special issue belongs to the Section Stem Cells)
The Multifaceted Role of Molecular Chaperones in Cancer: Pro-Tumoral or Therapeutic Function
edited by and Federica Scalia
submission deadline 31 May 2026 | 1 articles | Viewed by 1673 | Submission Open
Keywords: molecular chaperones; cancer biology; carcinogenesis; tumor progression; diagnostic/prognostic biomarkers; anti-tumor therapeutic strategies; in vitro/in vivo experimental approaches; in silico computational approaches
Non-Coding RNAs as Regulators of Cellular Function and Disease
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 1482 | Submission Open
Keywords: non-coding RNAs; gene regulation; disease mechanisms; therapeutic targets; molecular mechanisms
Exploring the Structural and Functional Diversity of Proteins: Foundations of Life and Biological Complexity
edited by Jiabei Lin
submission deadline 31 May 2026 | 1 articles | Viewed by 755 | Submission Open
Keywords: AAA+ protein; RNA-binding protein; protein kinase; PTMs; protein structure; function; and diseases; protein and RNA homeostasis; neurodegeneration; cancer
G Protein-Coupled Receptors and Diseases
edited by
submission deadline 31 May 2026 | Viewed by 630 | Submission Open
Keywords: G protein-coupled receptor; taste receptor; microbiome; cancer; aging; neurodegenerative disease; cardiovascular disease; pulmonary hypertension; cell survival; cell death; apoptosis; autophagy; necroptosis; ferroptosis; proliferation
Molecular and Cellular Mechanisms of Type 1 Diabetes (T1D)
edited by Robert Sharp and
submission deadline 31 May 2026 | Viewed by 398 | Submission Open
Keywords: T1D; autoimmunity; type 1 diabetes; single-nucleotide polymorphisms (SNPs); viral/bacterial pathogens; T-cell biology; inflammation; pancreatic beta cells; immunoregulatory; molecular biology; cellular biology
(This special issue belongs to the Section Cellular Pathology)
Role of Lysosomes in Mediating Cancer Drug Resistance
edited by
submission deadline 31 May 2026 | Viewed by 203 | Submission Open
Keywords: drug resistance; autophagic cell death; lysosomal-mediated cell death; autophagy; apoptosis; lysosomal exocytosis; lysosomal sequestration; tumor microenvironment
(This special issue belongs to the Section Cell Microenvironment)
Sex Differences in Cardiovascular Structure and Function—from Mechanisms to Therapeutics submission deadline 31 May 2026 | Viewed by 173 | Submission Open
Keywords: cardiovascular diseases; sex hormones; sex differences; vascular and cell signaling; therapeutic targets
Molecular Mechanisms of Drug Delivery in Ophthalmology
edited by Alekha K. Dash and Surabhi Shukla
submission deadline 31 May 2026 | Viewed by 167 | Submission Open
Keywords: drug delivery; ophthalmology; nanocarriers; ocular barriers; molecular transport; targeted therapy; ocular gene delivery
(This special issue belongs to the Section Tissues and Organs)
Cellular and Molecular Basis of Brain Tumor
edited by , Tomasz S. Mandat, Grzegorz Turek and Radosław Mlak
submission deadline 31 May 2026 | Viewed by 165 | Submission Open
Keywords: brain tumor; glioma; tumor microenvironment; molecular oncology; epigenetics; tumor stem cells; biomarkers; therapeutic resistance; non-coding RNA; translational research
(This special issue belongs to the Section Cellular Pathology)
Brain Insulin Resistance in Neurodegenerative Disorders and Its Treatments
edited by Konrad Talbot
submission deadline 31 May 2026 | Viewed by 160 | Submission Open
Keywords: Alzheimer’ s disease; brain insulin resistance; Down syndrome; incretin receptor agonist; insulin; insulin resistance; multiple system atrophy; neurodegenerative disease; Parkinson’ s disease
(This special issue belongs to the Section Cellular Neuroscience)
Inflammatory Signaling and Vascular Dysfunction in Atherosclerosis
edited by and Jianzhong Shen
submission deadline 31 May 2026 | Viewed by 148 | Submission Open
Keywords: inflammation in atherosclerosis; atherothrombosis; cell signaling
Development and Characterization of Innovative In Vitro Models
edited by Fengyan Deng and Chongbei Zhao
submission deadline 31 May 2026 | Viewed by 139 | Submission Open
Keywords: 3D organoid development; iPSC; iPSC reprogramming; primary cell derivation; cell immortalization; disease model development; stem cell therapy; molecular biology; cell signaling
Immunotherapy-Induced Cardiotoxicity: Unraveling the Immune Landscape of Myocarditis
edited by
submission deadline 31 May 2026 | Viewed by 108 | Submission Open
Keywords: immunotherapy; immune checkpoints; adoptive cell therapy; cardiac adverse events; cardiac inflammation; immune checkpoint inhibitor associated myocarditis; cardiac immune landscape; innate immune response; adaptive immune response; myeloid cells; macrophages; antigen presentation & phagocytosis; T cells; T cell clonality; cytokines; chemokines; chemotaxis; immune crosstalk; immune– stromal crosstalk; multi-omics
Regulatory Mechanisms of Vascular Smooth Muscle Cells and Immune Cells in Vascular Disease Progression
edited by and
submission deadline 31 May 2026 | Viewed by 108 | Submission Open
Keywords: vascular smooth muscle cells; immune cells; inflammation; vascular disease; atherosclerosis; aneurysm; cellular crosstalk; phenotypic transition
(This special issue belongs to the Section Cells of the Cardiovascular System)
Extracellular Vesicles in Reproductive Communication: From Gametogenesis to Implantation
edited by and Osvaldo Bogado Pascottini
submission deadline 31 May 2026 | Viewed by 107 | Submission Open
Keywords: extracellular vesicles; reproductive biology; gametogenesis; oocyte maturation; embryo-maternal communication; implantation; reproductive disorders; epigenetic regulation; EV Cargo; intercellular signaling
Mitochondria Beyond Energy: Signaling, Immunity, and Cell Fate submission deadline 31 May 2026 | Viewed by 93 | Submission Open
Keywords: mitochondria; stem cells; cell fate; organogenesis; immunometabolism
Circadian Rhythms in Action: Cellular and Molecular Mechanisms Revealed by Model Organisms submission deadline 31 May 2026 | Viewed by 92 | Submission Open
Keywords: circadian rhythm; molecular regulation; cellular mechanisms; model organisms; time-restricted feeding; metabolism; aging; neurodegeneration
Skeletal Muscle Aging and Regeneration: Mitochondrial Health, Molecular Signaling, and Therapeutic Interventions
edited by
submission deadline 31 May 2026 | Viewed by 83 | Submission Open
Keywords: aging; skeletal muscle; regeneration; satellite cells; muscle stem cells; muscle wasting; mitochondria; fibro-adipogenic progenitor cells; repair
DNA Damage and Repair in Targeted Cancer Therapy
edited by Mohd Saleem Dar, Sajad Ahmad Bhat and
submission deadline 31 May 2026 | Viewed by 74 | Submission Open
Keywords: cancer cells; DNA damage and repair mechanism; genome organization; BER; NER; MMR; HR; and NHEJ; targeted therapy; inhibitors/PROATCS; drug resistance; drug toxicity; biomarkers; personalized medicine
Advances in Ion Channel Biology: From Molecular Mechanisms to Therapeutic Targets
edited by Shridhar Sanghvi, and
submission deadline 31 May 2026 | Viewed by 56 | Submission Open
Keywords: ion channels; electrophysiology; cryo-electron microscopy; channelopathy; membrane protein; gating mechanism; structural biology
Cellular Mechanisms and Therapeutic Potentials of Neurodevelopmental Defects submission deadline 31 May 2026 | Viewed by 55 | Submission Open
Keywords: neurodevelopmental disorders; neuronal connectivity; precocious therapies; synaptic plasticity; neurogenesis; glial function
(This special issue belongs to the Section Cellular Neuroscience)
Epigenetic and Cellular Regulation in Hematologic Disorders
edited by
submission deadline 31 May 2026 | Viewed by 54 | Submission Open
Keywords: epigenetics; hematologic disorders; leukemia; myelodysplastic syndrome; thrombosis; thrombocytopenia; bleeding
B Cells in Action: Interaction Dynamics and Functional Decisions
edited by Michael L. Atchison and
submission deadline 31 May 2026 | Viewed by 52 | Submission Open
Keywords: B cell development and differentiation; adaptive immunity; germinal center B cell; class-switch recombination; immunosuppression; cytokines; inflammation; epigenetic regulation; metabolic reprogramming; immune response
(This special issue belongs to the Section Cellular Immunology)
Endometrial Cancer: From Molecular Mechanisms to Therapeutic Approaches
edited by Tomaž Büdefeld and
submission deadline 31 May 2026 | Viewed by 47 | Submission Open
Keywords: endometrial cancer; genetic mutation; epigenetics; cell signaling; TIME; metastasis; biomarker; therapy; drug delivery; risk factor
Decoding Heart Failure: From Mechanisms to Treatment
edited by and Dirk L. Brutsaert
submission deadline 31 May 2026 | Viewed by 42 | Submission Open
Keywords: heart failure; pathological process; molecular mechanisms; cellular mechanisms; genetic mechanisms; therapeutic target
Cellular and Molecular Mechanisms of Heart Development
edited by Jun K. Takeuchi
submission deadline 31 May 2026 | Viewed by 41 | Submission Open
Keywords: heart development; cardiovascular; epigenetics; cell fate; differentiation; cardiac growth; cardiac morphogenesis; heart regeneration; cardiac organoid
Back to TopTop