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  • Review
  • Open Access
24 Citations
30,833 Views
31 Pages

Gene Therapy for Genetic Syndromes: Understanding the Current State to Guide Future Care

  • Marian L. Henderson,
  • Jacob K. Zieba,
  • Xiaopeng Li,
  • Daniel B. Campbell,
  • Michael R. Williams,
  • Daniel L. Vogt,
  • Caleb P. Bupp,
  • Yvonne M. Edgerly,
  • Surender Rajasekaran and
  • Jena M. Krueger
  • + 2 authors

3 January 2024

Gene therapy holds promise as a life-changing option for individuals with genetic variants that give rise to disease. FDA-approved gene therapies for Spinal Muscular Atrophy (SMA), cerebral adrenoleukodystrophy, β-Thalassemia, hemophilia A/B, re...

  • Review
  • Open Access
26 Citations
23,655 Views
12 Pages

Exploring DNA Damage and Repair Mechanisms: A Review with Computational Insights

  • Jiawei Chen,
  • Ravi Potlapalli,
  • Heng Quan,
  • Lingtao Chen,
  • Ying Xie,
  • Seyedamin Pouriyeh,
  • Nazmus Sakib,
  • Lichao Liu and
  • Yixin Xie

16 January 2024

DNA damage is a critical factor contributing to genetic alterations, directly affecting human health, including developing diseases such as cancer and age-related disorders. DNA repair mechanisms play a pivotal role in safeguarding genetic integrity...

  • Review
  • Open Access
30 Citations
13,483 Views
20 Pages

Trends in Biological Ammonia Production

  • Adewale Adeniyi,
  • Ibrahim Bello,
  • Taofeek Mukaila,
  • Niloy Chandra Sarker and
  • Ademola Hammed

Food production heavily depends on ammonia-containing fertilizers to improve crop yield and profitability. However, ammonia production is challenged by huge energy demands and the release of ~2% of global CO2. To mitigate this challenge, many researc...

  • Review
  • Open Access
10 Citations
12,285 Views
17 Pages

DNA Data Storage

  • Tomasz Buko,
  • Nella Tuczko and
  • Takao Ishikawa

The demand for data storage is growing at an unprecedented rate, and current methods are not sufficient to accommodate such rapid growth due to their cost, space requirements, and energy consumption. Therefore, there is a need for a new, long-lasting...

  • Review
  • Open Access
12 Citations
10,262 Views
20 Pages

Biomolecular Liquid–Liquid Phase Separation for Biotechnology

  • Sumit Shil,
  • Mitsuki Tsuruta,
  • Keiko Kawauchi and
  • Daisuke Miyoshi

1 April 2023

The liquid–liquid phase separation (LLPS) of biomolecules induces condensed assemblies called liquid droplets or membrane-less organelles. In contrast to organelles with lipid membrane barriers, the liquid droplets induced by LLPS do not have d...

  • Review
  • Open Access
35 Citations
10,058 Views
27 Pages

2 September 2024

Biobanking plays a pivotal role in biomedical research by providing standardized processing, precise storing, and management of biological sample collections along with the associated data. Effective data management is a prerequisite to ensure the in...

  • Review
  • Open Access
21 Citations
9,012 Views
14 Pages

Soil–water pollution is of serious concern worldwide. There is a public outcry against the continually rising problems of pollution to ensure the safest and healthiest subsurface environment for living beings. A variety of organic pollutants ca...

  • Article
  • Open Access
3 Citations
8,887 Views
14 Pages

11 July 2023

This article extends an exploration into renewed ethico-legal perspectives of genome editing technologies, examined from an evolved conceptualization of eugenics in contemporary human reproduction. Whilst the ethico-legal conundrums presented by geno...

  • Article
  • Open Access
2 Citations
8,133 Views
14 Pages

Principle Investigation and Method Standardization of Inhibition Zone Assay Based on Antimicrobial Peptides Extracted from Black Soldier Fly Larvae

  • Wenyue Shen,
  • Ranxia Xue,
  • Yanxia Liu,
  • Shibo Sun,
  • Xi Chen,
  • Dongye Sun,
  • Han Ouyang,
  • Yuxin Li,
  • Jianqiang Xu and
  • Weiping Xu
  • + 2 authors

9 August 2024

The black soldier fly is a valuable resource insect capable of transforming organic waste while producing antimicrobial peptides (AMPs). The inhibition zone assay (IZA) is a method used to demonstrate the antimicrobial activity of AMPs. This study ai...

  • Feature Paper
  • Review
  • Open Access
21 Citations
7,593 Views
31 Pages

Hydroponics with Microalgae and Cyanobacteria: Emerging Trends and Opportunities in Modern Agriculture

  • Prabhaharan Renganathan,
  • Edgar Omar Rueda Puente,
  • Natalia V. Sukhanova and
  • Lira A. Gaysina

22 July 2024

The global population is expected to reach 9.5 billion, which means that crop productivity needs to double to meet the growing population’s food demand. Soil degradation and environmental factors, such as climate events, significantly threaten...

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BioTech - ISSN 2673-6284