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  • Article
  • Open Access
45 Views
19 Pages

Objectives: To evaluate regional anatomical differences in brain volume, surface area, and cortical thickness between children with breath-holding spells (BHSs) and a control group using morphometric MRI analyses. Methods: Three-dimensional T1-weight...

  • Article
  • Open Access
128 Views
18 Pages

Background: This study aimed to investigate the association between femoroacetabular impingement (FAI) morphology and femoral head bone marrow edema of unknown etiology on hip magnetic resonance imaging (MRI), and to assess the added value of compute...

  • Article
  • Open Access
101 Views
11 Pages

Background/Objectives: Tissue conductivity reflects ionic composition (e.g., sodium), providing critical insights into various diseases. Ultrashort echo time quantitative conductivity mapping (UTE-QCM) offers a method to obtain this information, whic...

  • Article
  • Open Access
196 Views
16 Pages

Comparison of Clinical Performance Between Digital Breast Tomosynthesis and MammouS-N

  • Sung Ui Shin,
  • Mijung Jang,
  • Bo La Yun,
  • Su Min Cho,
  • Yoon Yeong Choi,
  • Bohyoung Kim,
  • Min Jung Kim and
  • Sun Mi Kim

Background/Objectives: We compared the visibility of breast cancer using the newly developed standing automated breast ultrasound system (MammouS-N) and digital breast tomosynthesis (DBT), and identified factors influencing lesion visibility. Methods...

  • Article
  • Open Access
130 Views
21 Pages

Background: Emergency radiology often demands rapid integration of clinical cues, biochemical markers, and imaging findings to support time-critical diagnostic reasoning. However, educational resources that explicitly structure this interdisciplinary...

  • Article
  • Open Access
147 Views
16 Pages

Background: We aimed to determine paranasal sinus volumes using 3D volumetric measurements and to evaluate the effect of anatomical variations on these volumes, ensuring balanced age and sex distribution during childhood. Methods: Thirteen age groups...

  • Article
  • Open Access
148 Views
11 Pages

Objective: The number of operators performing mechanical thrombectomy (MT) may influence procedural outcomes; however, evidence remains limited and conflicting. This study aimed to comprehensively evaluate the impact of single versus dual operators o...

  • Article
  • Open Access
205 Views
22 Pages

Clinical Image Quality and Reader Variability in 3D Synthetic Brain MRI Compared with Conventional MRI

  • Alexander von Hessling,
  • Chloé Sieber,
  • Maria Blatow,
  • Christian Berner,
  • Dirk Lehnick and
  • Frauke Kellner-Weldon

Background/Objectives: This study evaluated the clinical image quality of three-dimensional synthetic MRI (3D SI) compared with conventional MRI (cMRI), focusing on tissue contrast, anatomical detail, and motion sensitivity. Methods: Patients with no...

  • Article
  • Open Access
137 Views
15 Pages

Background/Objectives: This study aimed to investigate the relationship between carotid artery anatomy and geometry and white matter hyperintensities (WMH) and to determine whether it is a risk factor for the disease. Methods: The geometry and anatom...

  • Article
  • Open Access
283 Views
18 Pages

Overestimation of the Apparent Diffusion Coefficient in Diffusion-Weighted Imaging Due to Residual Fat Signal and Out-of-Phase Conditions

  • Maher Dhanani,
  • Dominika Skwierawska,
  • Tristan Anselm Kuder,
  • Sabine Ohlmeyer,
  • Michael Uder,
  • Sebastian Bickelhaupt and
  • Frederik Bernd Laun

Background/Objectives: Diffusion-weighted imaging (DWI) is a magnetic resonance technique used to map the apparent diffusion coefficient (ADC) of water in human tissue. ADC assessment plays a central role in clinical diagnostics, as malignant tissues...

  • Review
  • Open Access
493 Views
13 Pages

Background: Pelvic floor dysfunction, more prevalent in women but affecting both genders, impairs sphincter control and sexual health, and causes pelvic pain. Pelvic floor muscle (PFM) training is the first-line treatment for urinary incontinence, su...

  • Article
  • Open Access
293 Views
12 Pages

Background: The pterygomaxillary region is a complex anatomical area formed by the junction of the maxillary, palatine, and sphenoid bones and contains critical neurovascular structures. Accurate assessment of this region during Le Fort I osteotomy i...

  • Systematic Review
  • Open Access
286 Views
16 Pages

Background/Objectives: Pancreatic cancer is among the most aggressive malignancies, with poor survival rates. Emerging evidence suggests that body composition, including skeletal muscle mass and adiposity distribution, plays a crucial role in predict...

  • Article
  • Open Access
353 Views
10 Pages

Super-Resolution Deep Learning Reconstruction Improves Image Quality of Dynamic Myocardial Computed Tomography Perfusion Imaging

  • Yusuke Kobayashi,
  • Yuki Tanabe,
  • Tomoro Morikawa,
  • Kazuki Yoshida,
  • Kentaro Ohara,
  • Takaaki Hosokawa,
  • Takanori Kouchi,
  • Shota Nakano,
  • Osamu Yamaguchi and
  • Teruhito Kido

Background/Objectives: Super-resolution deep-learning reconstruction (SR-DLR) is an advanced image reconstruction technique, but its effect on dynamic myocardial computed tomography perfusion (CTP) imaging has not been evaluated. This study aimed to...

  • Correction
  • Open Access
193 Views
2 Pages

Correction: Honda et al. Visual Evaluation of Ultrafast MRI in the Assessment of Residual Breast Cancer After Neoadjuvant Systemic Therapy: A Preliminary Study Association with Subtype. Tomography 2022, 8, 1522–1533

  • Maya Honda,
  • Masako Kataoka,
  • Mami Iima,
  • Rie Ota,
  • Akane Ohashi,
  • Ayami Ohno Kishimoto,
  • Kanae Kawai Miyake,
  • Marcel Dominik Nickel,
  • Yosuke Yamada and
  • Yuji Nakamoto
  • + 1 author

This correction addresses several errors identified in the original publication [...]

  • Article
  • Open Access
323 Views
14 Pages

Background: In computed tomography (CT), automatic exposure control (AEC) determines the tube current and thus the radiation dose based on scout images. We investigated CT dose modulation using two versions of CARE Dose 4D, Siemens AEC software. Meth...

  • Article
  • Open Access
578 Views
34 Pages

Detection and Classification of Alzheimer’s Disease Using Deep and Machine Learning

  • Muhammad Zaeem Khalid,
  • Nida Iqbal,
  • Babar Ali,
  • Jawwad Sami Ur Rahman,
  • Saman Iqbal,
  • Lama Almudaimeegh,
  • Zuhal Y. Hamd and
  • Awadia Gareeballah

Background/Objectives: Alzheimer’s disease is the leading cause of dementia, marked by progressive cognitive decline and a severe socioeconomic burden. Early and accurate diagnosis is crucial to enhancing patient outcomes, yet traditional clini...

  • Article
  • Open Access
376 Views
14 Pages

Objective: Axillary lymph node changes are frequently observed in patients with HIV, yet their radiological characteristics and clinical significance remain underexplored. This study aimed to evaluate the association between axillary lymph node compu...

  • Article
  • Open Access
586 Views
14 Pages

Altered Functional Connectivity of Amygdala Subregions with Large-Scale Brain Networks in Schizophrenia: A Resting-State fMRI Study

  • Rasha Rudaid Alharthi,
  • Duaa Banaja,
  • Adnan Alahmadi,
  • Jaber Hussain Alsalah,
  • Arwa Baeshen,
  • Ali H. Alghamdi,
  • Magbool Alelyani and
  • Njoud Aldusary

Objective: This study aimed to investigate the functional connectivity (FC) of three amygdala subregions—the laterobasal amygdala (LBA), centromedial amygdala (CMA), and superficial amygdala (SFA)—with large-scale brain networks in indivi...

  • Review
  • Open Access
1 Citations
1,524 Views
27 Pages

Cancer-Associated Fibroblasts: Clinical Applications in Imaging and Therapy

  • Neda Nilforoushan,
  • Ashkan Khavaran,
  • Maierdan Palihati,
  • Yashvi Patel,
  • Anna O. Giarratana,
  • Jeeban Paul Das and
  • Kathleen M. Capaccione

17 December 2025

Cancer-associated fibroblasts (CAFs) are an abundant and diverse cell population within tumor microenvironments of solid tumors. Multiple subtypes of CAFs, defined by molecular and functional markers, have been described in the literature. CAFs contr...

  • Article
  • Open Access
390 Views
16 Pages

Prediction of Breast Radiation Absorbed Dose Chest CT Examinations Using Machine Learning Techniques

  • Sevgi Ünal,
  • Remzi Gürfidan,
  • Merve Gürsoy Bulut and
  • Mustafa Fazıl Gelal

16 December 2025

Background/Objectives: The breast is a highly radiosensitive organ that is directly exposed to ionizing radiation during chest computed tomography (CT) examinations. Excessive radiation exposure increases the risk of radiation-induced malignancies, h...

  • Article
  • Open Access
396 Views
11 Pages

16 December 2025

Background: Accurate volumetry and imaging characterization of chronic subdural hematoma (cSDH) are essential for prognostication and treatment planning, but manual assessment is time-consuming and therefore underutilized. Methods: We retrospectively...

  • Article
  • Open Access
414 Views
12 Pages

Pilot Evaluation of a Deep Learning Model for Nasogastric Tube Verification on Chest Radiographs: A Single-Center Retrospective Study

  • Sang Won Park,
  • Doohee Lee,
  • Jae Eun Song,
  • Yoon Kim,
  • Hyun-Soo Choi,
  • Seung-Joon Lee,
  • Woo Jin Kim,
  • Kyoung Min Moon and
  • Oh Beom Kwon

15 December 2025

Background: Accurate confirmation of nasogastric (NG) tubes is essential for patient safety, but delays and variability in interpretation remain common in clinical practice. Deep learning (DL) models have shown potential for assisting in this task, b...

  • Article
  • Open Access
674 Views
12 Pages

Aortic Valve Calcium Scoring Using True and Virtual Non-Contrast Reconstructions on Photon-Counting CT with Differing Slice Increments: Impact on Calcium Severity Classifications

  • Mandeep Singh,
  • Amirhossein Moaddab,
  • Doosup Shin,
  • Jonathan Weber,
  • Karen Chau,
  • Ali H. Dakroub,
  • Roosha Parikh,
  • Karli Pipitone,
  • Ziad A. Ali and
  • Omar K. Khalique

11 December 2025

Background/Objectives: Aortic valve calcification is commonly evaluated using 3.0 mm true non-contrast (TNC) computed tomography (CT) images. This study evaluates the reproducibility of virtual non-contrast (VNC) reconstructions at different slice in...

  • Article
  • Open Access
468 Views
15 Pages

10 December 2025

Background/Objectives: Breast cancer is one of the most common malignancies in women worldwide. Early diagnosis and accurate classification in breast cancer detection are among the most critical factors determining treatment success and patient survi...

  • Article
  • Open Access
375 Views
16 Pages

5 December 2025

Background/Objectives: To identify preoperative MRI features using computer-assisted diagnosis (CAD) that are associated with invasive disease-free survival (IDFS) and distant metastasis-free survival (DDFS) in patients with primarily operable triple...

  • Article
  • Open Access
404 Views
14 Pages

Quantitative Magnetic Resonance Imaging of the Forearm in Myotonic Dystrophy Type 1

  • Sydney Eierle,
  • Tanja Taivassalo,
  • Hyunjun Park,
  • Korey D. Cooke,
  • Zahra Moslemi,
  • Sean C. Forbes,
  • Glenn A. Walter,
  • Krista Vandenborne,
  • S. H. Subramony and
  • Donovan J. Lott

5 December 2025

Introduction: Myotonic dystrophy type 1 is the most prevalent muscular dystrophy in adults, characterized by weakness, impaired functional abilities, and myotonia. However, little is known about the relationship between quantitative MRI measures (fat...

  • Article
  • Open Access
498 Views
15 Pages

Evaluation of Projection Images for Visual Quality Control of Automated Left and Right Lung Segmentations on T1-Weighted MRI in Large-Scale Clinical Cohort Studies

  • Tobias Norajitra,
  • Christopher L. Schlett,
  • Ricarda von Krüchten,
  • Prerana Agarwal,
  • Ashis Ravindran,
  • Thuy Duong Do,
  • Lisa Kausch,
  • Stefan Karrasch,
  • Hans-Ulrich Kauczor and
  • Claudius Melzig
  • + 1 author

29 November 2025

Background/Objectives: To assess diagnostic accuracy of two-dimensional (2D) projection methods for rapid visual quality control of automated volumetric (3D) lung segmentations compared with slice-based 3D review of segmentation results for applicati...

  • Article
  • Open Access
790 Views
11 Pages

A Question of Dose? Ultra-Low Dose Chest CT on Photon-Counting CT in People with Cystic Fibrosis

  • Marcel Opitz,
  • Matthias Welsner,
  • Halil I. Tazeoglu,
  • Florian Stehling,
  • Sivagurunathan Sutharsan,
  • Dirk Westhölter,
  • Erik Büscher,
  • Christian Taube,
  • Nika Guberina and
  • Marko Frings
  • + 7 authors

27 November 2025

Objective: Chest computed tomography (CT) is a key component of the diagnostic assessment of people with cystic fibrosis (PwCF) and is increasingly replacing chest radiography. Due to improvements in life expectancy, radiation exposure has become a g...

  • Article
  • Open Access
1,028 Views
14 Pages

Quantitative Ultrasound Grayscale Analysis and Size of Benign and Malignant Solid Thyroid Nodules

  • Salahaden R. Sultan,
  • Faisal Albin Hajji,
  • Abdulrahman Alhazmi,
  • Shahad Alamri,
  • Abrar Alsulami,
  • Ahmed Albukhari,
  • Asseel Filimban,
  • Bander Almutairi,
  • Ahmad Albngali and
  • Abrar Alfatni
  • + 4 authors

27 November 2025

Background: Ultrasound is the primary imaging modality for evaluating thyroid nodules, with echogenicity and nodule size serving as parameters for malignancy risk stratification. Though the TI-RADS classification system is standardized, interpretatio...

  • Article
  • Open Access
763 Views
15 Pages

Accuracy of Ultra-Fast Low-Field MRI (0.55 T) for Lung Nodule Detection with Ultra-Short Echo Time Sequences

  • Maximilian Hinsen,
  • Armin Michael Nagel,
  • Nadine Bayerl,
  • Hans-Peter Fautz,
  • Thomas Benkert,
  • Matthias Stefan May,
  • Michael Uder and
  • Rafael Heiss

26 November 2025

Lung nodules are a common radiological finding that can be caused by a variety of reasons, ranging from benign granulomas and scarring to the early stages of primary lung malignancies and metastases [...]

  • Article
  • Open Access
489 Views
17 Pages

3D Imaging of Proton FLASH Radiation Using a Multi-Detector Small Animal PET System

  • Wen Li,
  • Yuncheng Zhong,
  • Youfang Lai,
  • Lingshu Yin,
  • Daniel Sforza,
  • Devin Miles,
  • Heng Li and
  • Xun Jia

26 November 2025

Objectives: Ultra-high dose-rate FLASH radiotherapy has demonstrated strong potential in reducing normal tissue toxicity while maintaining effective tumor control. However, its underlying radiobiological mechanisms remain unclear, highlighting the ne...

  • Article
  • Open Access
1,040 Views
13 Pages

Multimodal CT and MRI Radiomics Integrated with Clinical Models Predict Pathological Complete Response in ESCC Following Neoadjuvant Immunochemotherapy

  • Longgao Liu,
  • Chufeng Zeng,
  • Lizhi Liu,
  • Shumin Zhou,
  • Weihua Wu,
  • Peng Lin,
  • Jianhua Fu,
  • Tiehua Rong,
  • Xu Zhang and
  • Xiaodong Su

19 November 2025

Background: This research focused on evaluating the utility of multimodal radiomics integrated with machine learning to predict pathological complete response (pCR) in a prospective cohort of esophageal squamous cell carcinoma (ESCC) patients undergo...

  • Article
  • Open Access
674 Views
15 Pages

14 November 2025

Background: Preoperative evaluation in bariatric surgery aims to minimize perioperative risks and identify comorbid abdominal pathologies that may influence surgical planning. The role of routine abdominal ultrasonography (USG) remains debatable. Met...

  • Article
  • Open Access
985 Views
13 Pages

13 November 2025

Rationale and Objective: Medical imaging, particularly computed tomography (CT), is the largest man-made contributor to collective radiation exposure. This study compares methods for assessing CT radiation dose, focusing on thoracic examinations. Pop...

  • Article
  • Open Access
721 Views
18 Pages

Prediction of Microsatellite Instability in Colorectal Cancer Using Two Internally Validated Radiomic Models

  • Antonio Galluzzo,
  • Ginevra Danti,
  • Linda Calistri,
  • Diletta Cozzi,
  • Daniele Lavacchi,
  • Daniele Rossini,
  • Lorenzo Antonuzzo,
  • Sebastiano Paolucci,
  • Francesca Castiglione and
  • Vittorio Miele
  • + 2 authors

13 November 2025

Objectives: To develop two different radiomic models based on preoperative contrast-enhanced computed tomography (PP CT) to predict microsatellite instability (MSI) in patients with colorectal cancer (CRC) before surgery. Methods: PP CT scans of 115...

  • Article
  • Open Access
782 Views
23 Pages

Photon-Counting Micro-CT for Bone Morphometry in Murine Models

  • Rohan Nadkarni,
  • Zay Yar Han,
  • Alex J. Allphin,
  • Darin P. Clark,
  • Alexandra Badea and
  • Cristian T. Badea

13 November 2025

Background/Objectives: This study evaluates photon-counting CT (PCCT) for the imaging of mouse femurs and investigates how APOE genotype, sex, and humanized nitric oxide synthase (HN) expression influence bone morphology during aging. Methods: A cust...

  • Review
  • Open Access
1 Citations
3,020 Views
38 Pages

Spontaneous Pneumothorax: A Review of Underlying Etiologies and Diagnostic Imaging Modalities

  • Rupali Jain,
  • Vinay Kandula,
  • Drew A. Torigian and
  • Achala Donuru

7 November 2025

This review focuses on the diverse etiologies of secondary spontaneous pneumothorax (SSP) and the crucial role of imaging in their diagnosis. Unlike primary spontaneous pneumothorax (PSP), which is typically due to ruptured blebs, SSP results from a...

  • Article
  • Open Access
841 Views
11 Pages

5 November 2025

Purpose: To compare retinal thickness measurements obtained with the Optos Monaco and Heidelberg Spectralis optical coherence tomography (OCT) systems across 9 Early Treatment Diabetic Retinopathy Study (ETDRS) sectors in a cohort comprising normal e...

  • Article
  • Open Access
690 Views
19 Pages

30 October 2025

Objectives: Kidneytumors, particularly renal cell carcinoma (RCC), represent a critical public health concern due to their prevalence and the severe consequences of late diagnosis. Traditional diagnostic techniques, though widely used, are often limi...

  • Article
  • Open Access
1,703 Views
23 Pages

30 October 2025

Background: Pneumothorax (PTX) requires rapid recognition in emergency and critical care. Lung ultrasound (LUS) offers a fast, radiation-free alternative to computed tomography (CT), but its accuracy is limited by operator dependence. Artificial inte...

  • Article
  • Open Access
824 Views
15 Pages

Electron Density and Effective Atomic Number as Quantitative Biomarkers for Differentiating Malignant Brain Tumors: An Exploratory Study with Machine Learning

  • Tsubasa Nakano,
  • Daisuke Hirahara,
  • Tomohito Hasegawa,
  • Kiyohisa Kamimura,
  • Masanori Nakajo,
  • Junki Kamizono,
  • Koji Takumi,
  • Masatoyo Nakajo,
  • Fumitaka Ejima and
  • Takashi Yoshiura
  • + 11 authors

29 October 2025

Objectives: The potential use of electron density (ED) and effective atomic number (Zeff) derived from dual-energy computed tomography (DECT) as novel quantitative imaging biomarkers for differentiating malignant brain tumors was investigated. Method...

  • Article
  • Open Access
1,007 Views
19 Pages

Dose-Dependent Analysis of Image Quality in Pediatric Head CT Scans Across Different Scanners to Optimize Clinical Protocols Using Phantom-Based Assessment

  • Hiroshi Kuwahara,
  • Mitsuaki Ojima,
  • Tsuneko Kawamura,
  • Daisuke Saitou,
  • Kazunari Andou,
  • Eiji Ariga,
  • Kotaro Hasegawa and
  • Michiaki Kai

27 October 2025

Background/Objectives: Optimization of pediatric head computed tomography (CT) protocols is essential to minimize radiation exposure while maintaining diagnostic image quality. Previous studies mainly relied on phantom-based measurements or visual as...

  • Article
  • Open Access
871 Views
11 Pages

Prevalence and Significance of Incidental Findings in Multiparametric Magnetic Resonance Imaging of the Prostate

  • David Weiß,
  • Arne Bischoff,
  • Michael Brönnimann,
  • Matteo Haupt and
  • Martin Maurer

23 October 2025

Objective: This study aims to assess the prevalence of clinically significant incidental findings as well as incidental findings of minor clinical significance in multiparametric MRI (mpMRI) of the prostate. Materials and Methods: A retrospective ana...

  • Article
  • Open Access
1 Citations
1,182 Views
17 Pages

22 October 2025

Background/Objectives: Cerebral blood flow (CBF) and cerebral blood volume (CBV) are critical perfusion metrics in diagnosing ischemic stroke. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) enables the evaluation of these cerebral per...

  • Article
  • Open Access
1,167 Views
16 Pages

Diagnostic Performance of CBCT in Detecting Different Types of Root Fractures with Various Intracanal Post Systems

  • Serhat Efeoglu,
  • Ecem Ozgur,
  • Aysenur Oncu,
  • Ahmet Tohumcu,
  • Rana Nalcaci and
  • Berkan Celikten

21 October 2025

Objective: This study aimed to evaluate the diagnostic accuracy of two cone beam computed tomography (CBCT) devices using 18 imaging modalities in detecting root fractures—vertical, horizontal, and oblique—in teeth with intracanal post sy...

  • Article
  • Open Access
727 Views
25 Pages

20 October 2025

Objective: Medical Visual Question Answering (Med-VQA), a key technology that integrates computer vision and natural language processing to assist in clinical diagnosis, possesses significant potential for enhancing diagnostic efficiency and accuracy...

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Tomography - ISSN 2379-139X