Most Recent

Cellulite, a multifactorial condition affecting approximately 98% of women, is characterised by dermal and subcutaneous architectural changes that compromise skin texture and elasticity. Its progression is closely linked to hormonal, vascular, and in...

This study demonstrates the effectiveness of ultrasound-assisted extraction (UAE) using butylene glycol for recovering antioxidant bioactive compounds from Rosa damascena petals. Extraction was conducted using 40% (w/v) butylene glycol, a 15 min trea...

Chronic ultraviolet (UV) exposure disrupts dermal collagen homeostasis and accelerates skin aging. This study evaluated the protective effects of black ginseng extract (BGE) against UV-induced photoaging in human dermal fibroblasts. BGE restored coll...

Polynucleotides purified through High Purification Technology (PN HPT), combined with hyaluronic acid (HA), represent a novel injectable strategy to improve skin quality in aesthetic medicine. This real-world data collection aimed to evaluate the saf...

The development of innovative cosmetic ingredients has driven growing interest in emulsion systems that combine performance, stability, and sustainability. Pickering emulsions can form physically stable systems by adsorbing solid particles at the oil...

Acne vulgaris is a prevalent dermatological disorder characterized by excessive sebum production, impaired skin hydration, enlarged pores, and persistent lesions. Chemical peeling is a well-established procedure in cosmetic dermatology, while microne...

Skin irritation and itching, often intense, are common consequences of mosquito bites. Interest in cosmetics formulated with natural ingredients has markedly increased among consumers, perceiving them as healthier, safer and more sustainable. We deve...

Hair loss is a prevalent condition with various causes, and effective treatments are in high demand. Cacumen Platycladi (Platycladus orientalis leaves), a traditional Chinese medicine, has been historically used to prevent hair loss. This study aimed...

Objective: This study aimed to design and clinically evaluate a bespoke cosmetic formulation tailored to individual skin characteristics and user preferences, focusing on hydration and barrier recovery in mature, therapy-affected skin. In addition, t...

Oxidative stress is a major factor in skin aging and various skin pathologies. Environmental pollutants exacerbate this stress by generating reactive oxygen species (ROS), disrupting the skin’s redox balance. Pycnogenol^®, a French maritime...

The cosmetic industry is undergoing a deep transformation driven by rapid innovation, evolving consumer expectations, and increasing demands for sustainability. Formulators are required to design products that combine functional efficacy, stability,...

Caffeoyl hexapeptide-9 (CH-9) is a novel cosmetic peptide designed by conjugating hexapeptide-9 (H-9), a known collagen-mimetic peptide with established skin anti-aging activity, with caffeic acid (CA) via an amide bond, leveraging peptide-drug conju...

Plant oils are increasingly explored as sustainable functional ingredients in topical emulsions due to their emollient properties and reported photoprotective potential. This study aimed to formulate physically stable W/O emulsions containing selecte...

Reactive oxygen species (ROS) are a major cause of skin aging, leading to oxidation and cleavage of collagen that supports skin structure. Previous studies have demonstrated that Magnolia officinalis var. officinalis (M. officinalis) dry extract redu...

This study developed a biodegradable dissolvable face mask incorporating liposomal kojic acid (KA) and licochalcone A from licorice extract (LE) to enhance skin delivery and performance. Liposomes were prepared by thin-film hydration method. The film...

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disorder. Revodiol Calming Cream^® (RCC) is a novel dermocosmetic product containing cannabidiol (CBD) and Annona cherimola fruit extract, designed for the management of atopic-pron...

Hair loss disorders, particularly androgenetic alopecia (AGA), are common conditions that carry significant psychosocial impact. Current standard therapies, including minoxidil, finasteride, and hair transplantation, primarily slow progression or re-...

This study evaluated the thermal properties, crystallinity, particle size, morphology, and in vivo local inflammation and persistence of two poly-L-lactic acid (PLLA) injectable implants, Sculptra^® (PLLA-SCA) and GANA V^® (PLLA-GA). PLLA-SCA a...

Surfactants are commonly employed in cleaning, cosmetic, and pharmaceutical formulations due to their ability to lower surface tension and facilitate the formation of emulsions, foams, and dispersions. Recent research highlights the advantages of syn...

Cosmeceutical peptides (CPs), which modulate various biological activities, including skin regeneration and wound healing, have emerged as promising agents in skincare. In this study, we investigated the regenerative and wound healing potential of a...

Plant-derived exosome-like extracellular vesicles (PELVs) have recently emerged as novel bioactive materials. Although members of the Orchidaceae family have been reported to possess various biological activities and are widely used as cosmetic ingre...

Melasma management is challenged by heterogeneity in patient presentation, particularly among individuals with darker skin tones. This study applied k-means clustering, an unsupervised machine learning algorithm that partitions data into k distinct c...

Platycladus orientalis exhibits significant potential as an antioxidant, anti-inflammatory, and hair growth-promoting ingredient, while the low bioavailability of raw Platycladus orientalis leaves extracts limits their further application. In this st...

The pursuit of fine chemicals from natural sources is advancing rapidly, driven by a growing demand for safe, sustainable, and high-performance ingredients in cosmetic and pharmaceutical formulations. Emerging extraction and biotransformation technol...

The growing demand for sustainable cosmetic products and the rapid expansion of the pet care market have driven the search for environmentally friendly, safe, and effective alternatives to conventional formulations. In this study, an ecofriendly soli...

Achieving optimal skin penetration with bioactive cosmetic ingredients, such as epidermal growth factor (EGF), presents ongoing challenges. This study introduces a novel elastosome-based EGF delivery system co-loading dexpanthenol, which achieves sup...

Adipose-derived mesenchymal stem cells (AD-MSCs) secrete various growth factors that activate skin cells. This study investigated the effects of crude extracts and isolated compounds, hitorin A and hitorin B, from Chloranthus quadrifolius on AD-MSCs....

Ceramides are central to stratum corneum barrier organization and hydration. Beyond topical replenishment, ceramide-stimulating strategies increasingly aim to enhance endogenous ceramide biosynthesis, processing, and homeostatic remodeling in coordin...

Post-oncologic skin is subject to multiple structural and functional impairments following chemotherapy and radiotherapy, including delayed epidermal turnover, compromised barrier integrity, and mitochondrial dysfunction. These changes can lead to pe...

Background/Objectives: Understanding how plant-derived extracts influence the rheological and sensory behavior of emulsions is crucial for developing stable and consumer-appealing formulations. Although walnut leaf extract (Juglans regia L.) is recog...

Introduction: Artificial intelligence (AI) has developed into an increasingly important tool in dermatology. While new technologies integrated within laser devices are emerging, there is a lack of data on the applicability of publicly available AI mo...

Skin hydration is a key indicator of skin health and stratum corneum (SC) integrity, yet its relationship with multi-dimensional physiological parameters remains incompletely understood. This study aimed to investigate the association between facial...

This study addresses the growing consumer demand for effective and sustainable hair care solutions by evaluating a novel bioactive crosslink repair complex designed to restore chemically damaged hair. The complex comprises itaconic acid, arginine, D-...

The pursuit of youthful, healthy skin remains one of the most compelling drivers in the cosmetics industry [...]

Background: Facial atrophic acne scars have a significant impact on patients’ psychosocial well-being and remain a therapeutic challenge. Existing treatments options are frequently limited by modest efficacy and adverse effects. The combination...

Orange peel waste has potential to be valorized from agro-industrial and food sectors to formulate products for personal hygiene and public health. This study presents the formulation of alcohol-based antibacterial gels incorporating essential oils e...

Alopecia is a multifactorial disorder in which immune, endocrine, metabolic, and microbial systems converge within the follicular microenvironment. In alopecia areata (AA), loss of immune privilege, together with interferon-γ- and interleukin-1...

This study introduces a novel oxygenating facial mask enriched with hemp seed extract, which uniquely combines advanced bubble-generating technology with botanically derived antioxidants for enhanced skin care. The innovative mask forms microbubbles...

Skin is constantly exposed to UV radiation. While topical sunscreens are the main preventative measure, oral photoprotective agents are emerging as promising systemic adjuncts, offering uniform, continuous protection. This study presents the results...

Like with skin, both men and women—regardless of ethnicity—gradually lose satisfaction with changes in hair brought about by ageing. Especially when such transition is apparent by others, and that the hair condition has a significant role...

Pequi (Caryocar brasiliense) oil is a lipid-rich natural ingredient with potential cosmetic applications, but its time-dependent clinical effects on skin remain underexplored. This study aimed to characterize pequi oil using GC-MS, develop a minimali...

Natural ingredients with soothing and skin-protecting effects are becoming increasingly popular in cosmetic science. Great interest has been directed to birch sap, a nutrient-rich fluid from Betula species. This study aimed to investigate whether bir...

The valorization of agricultural byproducts into functional cosmetic ingredients is a promising strategy for sustainable formulation development. In this work, raw Prinsepia utilis Royle seed residue powder (RPURSRP) which was discarded after oil pre...

Background: Eczematous dermatitis refers to a group of inflammatory skin disorders—including seborrheic, atopic, and contact dermatitis—characterized by epidermal barrier dysfunction and chronic inflammation. Disrupting the itch–scr...

Chronic low-grade inflammation and oxidative stress induced by the exposome represent key drivers of skin aging and related imperfections. The development of experimental models suitable for studying these metabolic processes is therefore of primary...

Aesthetic mesotherapy—the subcutaneous injection of key ingredients for cellular function—has gained popularity as a skin rejuvenation treatment. We developed a cosmetic serum, incorporating 11 ingredients frequently used in meso-injectio...

The search for alternatives to animal testing in cosmetics has encouraged the development of in vitro systems capable of evaluating formulation-driven biophysical parameters assessed on human skin. This study presents a cell-free tri-layered chitosan...

Background: Melasma is a chronic hyperpigmentation disorder, often therapy-resistant. Minimally invasive combinations of chemical stimulators and serums show promise. This study evaluated trichloroacetic acid stabilized with hydrogen peroxide and koj...

Alopecia areata (AA) is a chronic autoimmune disease characterized by non-scarring hair loss, where pathogenesis is closely linked to the collapse of hair follicle immune privilege and dysregulated T-cell responses. Increasing evidence suggests that...

Hyaluronic acid (HA) fillers represent the most frequently performed minimally invasive procedures for facial rejuvenation, yet their overall safety profile is critically influenced by the cross-linking technology employed. Polyethylene glycol diglyc...