Cosmetics, Volume 12, Issue 6

Orange peel waste has potential to be valorized from agro-industrial and food sectors to formulate products for personal hygiene and public health. This study presents the formulation of alcohol-based antibacterial gels incorporating essential oils e...

Alopecia is a multifactorial disorder in which immune, endocrine, metabolic, and microbial systems converge within the follicular microenvironment. In alopecia areata (AA), loss of immune privilege, together with interferon-γ- and interleukin-1...

This study introduces a novel oxygenating facial mask enriched with hemp seed extract, which uniquely combines advanced bubble-generating technology with botanically derived antioxidants for enhanced skin care. The innovative mask forms microbubbles...

Skin is constantly exposed to UV radiation. While topical sunscreens are the main preventative measure, oral photoprotective agents are emerging as promising systemic adjuncts, offering uniform, continuous protection. This study presents the results...

Like with skin, both men and women—regardless of ethnicity—gradually lose satisfaction with changes in hair brought about by ageing. Especially when such transition is apparent by others, and that the hair condition has a significant role...

Pequi (Caryocar brasiliense) oil is a lipid-rich natural ingredient with potential cosmetic applications, but its time-dependent clinical effects on skin remain underexplored. This study aimed to characterize pequi oil using GC-MS, develop a minimali...

Natural ingredients with soothing and skin-protecting effects are becoming increasingly popular in cosmetic science. Great interest has been directed to birch sap, a nutrient-rich fluid from Betula species. This study aimed to investigate whether bir...

The valorization of agricultural byproducts into functional cosmetic ingredients is a promising strategy for sustainable formulation development. In this work, raw Prinsepia utilis Royle seed residue powder (RPURSRP) which was discarded after oil pre...

Background: Eczematous dermatitis refers to a group of inflammatory skin disorders—including seborrheic, atopic, and contact dermatitis—characterized by epidermal barrier dysfunction and chronic inflammation. Disrupting the itch–scr...

Chronic low-grade inflammation and oxidative stress induced by the exposome represent key drivers of skin aging and related imperfections. The development of experimental models suitable for studying these metabolic processes is therefore of primary...

Aesthetic mesotherapy—the subcutaneous injection of key ingredients for cellular function—has gained popularity as a skin rejuvenation treatment. We developed a cosmetic serum, incorporating 11 ingredients frequently used in meso-injectio...

The search for alternatives to animal testing in cosmetics has encouraged the development of in vitro systems capable of evaluating formulation-driven biophysical parameters assessed on human skin. This study presents a cell-free tri-layered chitosan...

Background: Melasma is a chronic hyperpigmentation disorder, often therapy-resistant. Minimally invasive combinations of chemical stimulators and serums show promise. This study evaluated trichloroacetic acid stabilized with hydrogen peroxide and koj...

Alopecia areata (AA) is a chronic autoimmune disease characterized by non-scarring hair loss, where pathogenesis is closely linked to the collapse of hair follicle immune privilege and dysregulated T-cell responses. Increasing evidence suggests that...

Hyaluronic acid (HA) fillers represent the most frequently performed minimally invasive procedures for facial rejuvenation, yet their overall safety profile is critically influenced by the cross-linking technology employed. Polyethylene glycol diglyc...

Background: Photoaging results from cumulative ultraviolet-induced damage, mainly affecting sun-exposed areas such as the face, neck, and forearms. It manifests with textural roughness, irregular pigmentation, and wrinkles, reflecting structural dege...

Background/Objective: The skin microbiome plays a pivotal role in barrier function, immune regulation, and overall skin health. Age-related changes and environmental stressors disrupt microbial homeostasis, contributing to inflammaging and esthetic c...

Since the causes of aging are diverse, anti-aging requires a wide range of strategies. Kampo, a traditional medicine of Japan, which has its roots in traditional Chinese medicine, is generally prepared by combining several natural compounds to produc...

The generation and stability of foam are critical attributes influencing the perceived efficacy and sensory experience of cleansing products like face cleansers and hair shampoos. This study rigorously investigated the influence of water hardness on...

Contact dermatitis is a highly prevalent inflammatory disease of the skin with substantial impact on patients’ quality of life and occupational function. Although randomized controlled trials (RCTs) provide the highest level of evidence for tre...

Skin sensitization is a critical endpoint in cosmetic safety assessment, necessitating reliable animal-free testing alternatives. Current established in chemico assays, such as the Direct Peptide Reactivity Assay and Amino acid Derivative Reactivity...

Skin aging is influenced by both internal and external factors, resulting in wrinkles, decreased elasticity and irregular pigmentation. Hyaluronic acid (HA), a key component of the extracellular matrix, is essential for skin hydration and structural...

(1) Background: Low-molecular-weight hyaluronic acid displays moisturizing and anti-aging properties and reduces UV-induced inflammation when applied topically. A 3 kDa sodium hyaluronate oligosaccharide (Extra-Low HA) was designed, and studies were...

Hydrogels have gained significant attention as effective vehicles for transdermal applications offering significant advantages in pharmaceutical and cosmetic applications. Their unique polymeric network structure enables efficient encapsulation and c...

Increasing experience in the use of PLLA-SCA™ suggests that a brief overview of recent studies and a standardization of treatment protocols based on new clinical data should be beneficial. The aim of this article is to provide guidance on the u...

Skin hydration is fundamental for maintaining epidermal barrier integrity and overall skin homeostasis. Beyond traditional moisturizing agents, recent research has highlighted the role of aquaporins (AQPs), transmembrane water channels, in regulating...

Numerous ingredients in trichological shampoos are advertised as “active against hair loss”; however, the body of evidence behind such claims seems very limited or, in many cases, nonexistent. The aim of this study was to compile an inven...

Passiflora ligularis (granadilla), widely cultivated in Colombia, contains secondary metabolites such as flavonoids, phenols, and pectins. Owing to their strong water-retention capacity, pectins are promising candidates for moisturizing cosmetic form...

Peptides are recognized as multifunctional bioactive ingredients in cosmetic science, as they offer diverse beneficial effects such as skin rejuvenation, anti-aging, and skin barrier enhancement. In this study, we applied a cheminformatics-assisted p...

Sisal (Agave sisalana) is a plant widely cultivated in Brazil for fiber extraction, generating large volumes of underutilized residues with pharmacological potential. In this study, an aqueous extract and its alcoholic fraction were obtained from the...

Skin hyperpigmentation is primarily regulated by melanogenesis, in which tyrosinase and related enzymes play pivotal roles. Probiotics have recently been attracting attention as a cosmetic ingredient due to their skin-friendly and eco-friendly proper...

This study presents a novel application of SVX, a recombinant spider silk-inspired biopolymer, for advanced haircare formulations, designed to protect bleached and color-treated hair. Two SVX-based treatments—a multifunctional leave-on serum an...

Natural shampoos are increasingly designed to provide multifunctional benefits beyond cleansing, including hair conditioning, scalp protection, and reduced irritation potential. POLEVAN^®, a proprietary levan-based polysaccharide produced enzymati...

Skin aging, including photoaging, is primarily triggered by chronic exposure to solar radiation, which induces free radical formation, cellular deoxyribonucleic acid (DNA) damage, and structural skin alterations. Achillea millefolium L. (Asteraceae)...

Androgenetic alopecia (AGA) is a prevalent, multifactorial hair disorder affecting a substantial portion of both males and females, with significant psychosocial consequences. Over the past decade, regenerative medicine has reshaped AGA treatment, of...

Hair loss and scalp dysfunction are prevalent concerns with limited non-medicinal long-term solutions. Growth factors and plant-derived extracellular vesicle (EV) represent promising regenerative approaches. In this exploratory randomized controlled...

Plant-derived extracellular vesicles (PDEVs) are rapidly gaining popularity in cosmetics and regenerative medicine due to their biocompatibility, natural origin and promising bioactive properties. Nevertheless, the absence of standardized guidelines...

Background: Melasma and facial hyperpigmentation are common dermatologic conditions that significantly impact patients’ quality of life. New approaches such as laser-assisted delivery of topical agents have been proposed to enhance treatment ou...

Skin aging is accelerated by both environmental factors—including ultraviolet (UV) radiation and pollution—and intrinsic processes such as chronic inflammaging. N-carbamylglutamate (NCG), an arginine precursor known for its benefits for g...

Hair can be significantly damaged following exposure to environmental agents and physical and chemical treatments. The aim of this study concerned the evaluation of the protective and restructuring efficacy of a hair mask containing two rice derivati...

Background: Creams are one of the most used cosmetic formulations due to their hydrating and restoring properties, pleasant texture, and the possibility to deliver hydrophobic and hydrophilic active ingredients. The study aims to develop and characte...

Introduction: Major manifestations of facial skin aging include the loss of firmness and elasticity, the appearance of wrinkles, and various pigmentary changes. Mesotherapy—both needle and microneedle-based—is a commonly chosen procedure...

The cashew apple (Anacardium occidentale L.) is rich in antioxidant bioactive constituents that have anti-aging and wound healing properties. The objective of this study is to evaluate the biological activities of cashew apple extract (CAE) and to im...

Background: Despite extensive phytochemical research on white tea varieties, flavonoid profiling in Baihao Yinzhen remains scarce. The development of green and efficient extraction methods is essential to facilitate its potential application in cosme...

The cosmetic industry is constantly evolving to create new formulations that offer controlled and specific release of active ingredients, as well as greater penetration, duration and stability of the resulting products. To fulfil all these objectives...

Polianthes tuberosa L. (PT) flower extracts exhibit considerable bioactivities, yet their application is often constrained by limited bioavailability and efficacy. In this study, fermentation of PT (FPT) using Rhodosporidium toruloides significantly...

Background: Titanium dioxide (TiO₂) is widely used as a physical filter in sunscreen formulations due to its ability to reflect and scatter radiation. The effectiveness of TiO₂-based preparations depends on particle size, influencing photoprotective...

Narrowband ultraviolet B (NB-UVB) phototherapy, used for treating skin diseases, can induce skin aging, cause inflammation, and reduce cell viability due to reactive oxygen species (ROS) generation. To mitigate these adverse effects, a multi-target p...

Background/Objectives: Inflammatory skin disorders such as dermatitis, psoriasis, and acne that affect patients’ quality of life and health require safe and effective active delivery systems. In Thai traditional medicine, Curcuma aromatica has...

Skin compatibility is a common issue and can often be worsened by certain ingredients in cosmetics. This is why developing well-balanced and -tolerated formulas is now an essential challenge. In this work we developed a cream rich in antioxidant, soo...