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Cosmetics, Volume 13, Issue 1

2026 February - 42 articles

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Articles (42)

  • Article
  • Open Access

Therapeutic Potential of Ozonized Glycerin in Skin Inflammation and Repair

  • John Ivarsson,
  • Anna Guiotto,
  • Giulia Trinchera,
  • Alessandra Pecorelli,
  • Gotaro Shiota and
  • Giuseppe Valacchi
Cosmetics2026, 13(1), 42;https://doi.org/10.3390/cosmetics13010042 
(registering DOI)

12 February 2026

Glycerin is a widely used ingredient in cosmetics due to its cost-effectiveness and safety. While often used to enhance the texture of cosmetics, current research has demonstrated that it improves cutaneous properties such as enhanced skin hydration...

  • Correction
  • Open Access

Correction: Chang et al. Centella asiatica L. Urb. Extracellular Vesicle and Growth Factor Essence for Hair and Scalp Health: A 56-Day Exploratory Randomized Trial. Cosmetics 2025, 12, 253

  • Tsong-Min Chang,
  • Chung-Chin Wu,
  • Huey-Chun Huang,
  • Ji-Ying Lu,
  • Ching-Hua Chuang,
  • Pei-Lun Kao,
  • Wei-Hsuan Tang,
  • Wang-Ju Hsieh,
  • Luke Tzu-Chi Liu and
  • Tsun-Yung Kuo
  • + 3 authors
Cosmetics2026, 13(1), 41;https://doi.org/10.3390/cosmetics13010041 
(registering DOI)

12 February 2026

Error in Table 1 [...]

  • Article
  • Open Access

11 February 2026

Naturally derived cosmetic enzymes from food-grade plant sources are increasingly sought after as sustainable and skin-compatible alternatives to conventional exfoliating agents; however, many existing plant proteases exhibit poor thermal stability,...

  • Article
  • Open Access

Comparative In Vitro Evaluation of Selected Essential Oils and Commercial Blends Against Skin-Associated Pathogens

  • Ruslan Bikmurzin,
  • Jurga Būdienė,
  • Rūta Daunoravičienė,
  • Ingrida Pumputienė and
  • Jūratė Graželytė

10 February 2026

Essential oils are widely used in cosmetic products and are valued for their antimicrobial properties. In this study, the in vitro antimicrobial activity of five pure essential oils (EOs) and five commercially available EO blends was comparatively ev...

  • Article
  • Open Access
29 Views
12 Pages

Harnessing miRNA Milk-Derived Exosomes for Hair Loss Disorders: In Vitro Modulation of WNT Signaling and Dermal Papilla Proliferation

  • Daniela Pinto,
  • Giorgia Mondadori,
  • Monica Cozzi,
  • Piero Tesauro,
  • Martin Hintersteiner,
  • Raúl López Domínguez,
  • Esperanza de Santiago Rodríguez,
  • Giammaria Giuliani and
  • Fabio Rinaldi

10 February 2026

Androgenetic alopecia (AGA) and telogen effluvium (TE) are common hair loss disorders characterized by dysregulated hair follicle cycling and impaired dermal papilla cell function. Emerging evidence indicates that exosomes are key mediators of interc...

  • Article
  • Open Access
117 Views
22 Pages

Sebum Regulating, Anti-Inflammatory, and Lipid Restoring Efficacy of Isorhamnetin Extracted from Opuntia ficus-indica: Results from a Randomized Double-Blind Clinical Trial

  • Federica Cascella,
  • Mohammad Reza Jahangiri Manesh,
  • Enza Cestone,
  • Gloria Roveda,
  • Martina Masciarelli,
  • Vincenzo Zaccaria,
  • Violetta Insolia and
  • Vincenzo Nobile

9 February 2026

Oily skin is a prevalent dermatological condition characterized by excessive sebum production, due to hyperactivity of the sebaceous glands. In this study, a randomized split-face clinical trial was conducted on 22 subjects with combination to oily s...

  • Systematic Review
  • Open Access
122 Views
19 Pages

9 February 2026

Perifollicular elastolysis (PE), frequently referred to as papular acne scars, is an underrecognized folliculocentric disorder; its clinicopathologic spectrum and management have not been comprehensively synthesized. We performed a systematic review...

  • Review
  • Open Access
462 Views
63 Pages

Bioactive Compounds for Topical and Minimally Invasive Cellulite Treatment and Skin Rejuvenation

  • Aura Rusu,
  • Raluca-Daniela Mazilu,
  • Blanka Székely-Szentmiklósi,
  • Octavia-Laura Oancea,
  • Corneliu Tanase,
  • Ioana-Andreea Lungu and
  • Gabriel Hancu

6 February 2026

Cellulite, a multifactorial condition affecting approximately 98% of women, is characterised by dermal and subcutaneous architectural changes that compromise skin texture and elasticity. Its progression is closely linked to hormonal, vascular, and in...

  • Article
  • Open Access
219 Views
20 Pages

6 February 2026

This study demonstrates the effectiveness of ultrasound-assisted extraction (UAE) using butylene glycol for recovering antioxidant bioactive compounds from Rosa damascena petals. Extraction was conducted using 40% (w/v) butylene glycol, a 15 min trea...

  • Article
  • Open Access
196 Views
16 Pages

Protective Mechanisms of Black Ginseng Extract on Collagen Synthesis in Chronic Photoaging

  • Yue Liu,
  • Xinxu Rao,
  • Chang Gao,
  • Tingzhi Zhang and
  • Shaowei Yan

6 February 2026

Chronic ultraviolet (UV) exposure disrupts dermal collagen homeostasis and accelerates skin aging. This study evaluated the protective effects of black ginseng extract (BGE) against UV-induced photoaging in human dermal fibroblasts. BGE restored coll...

  • Article
  • Open Access
198 Views
12 Pages

Real-World Evaluation of an Injectable Treatment Containing Polynucleotides Purified with High Purification Technology (PN HPT) and Hyaluronic Acid for Skin Quality Improvement in Facial and Body Areas

  • Antonella Savoia,
  • Simona Piscopo,
  • Mario Rasulo,
  • Umberto De Rosa,
  • Annamaria D’Ardis,
  • Luisa Cerutti,
  • Stefania Bizzarri,
  • Nicolle Tascon,
  • Annalisa Forni and
  • Carolina Prussia
  • + 2 authors

6 February 2026

Polynucleotides purified through High Purification Technology (PN HPT), combined with hyaluronic acid (HA), represent a novel injectable strategy to improve skin quality in aesthetic medicine. This real-world data collection aimed to evaluate the saf...

  • Article
  • Open Access
293 Views
26 Pages

Nanocellulose-Stabilized Pickering Emulsions for Cosmetic Applications

  • Ana Júlia Vaz de Melo Soares,
  • Dislyane Trajano da Silva,
  • Maryana Rogéria dos Santos,
  • Gleice Paula de Araújo,
  • Andréa Fernanda de Santana Costa,
  • Attilio Converti,
  • Italo José Batista Durval and
  • Leonie Asfora Sarubbo

30 January 2026

The development of innovative cosmetic ingredients has driven growing interest in emulsion systems that combine performance, stability, and sustainability. Pickering emulsions can form physically stable systems by adsorbing solid particles at the oil...

  • Article
  • Open Access
667 Views
18 Pages

28 January 2026

Acne vulgaris is a prevalent dermatological disorder characterized by excessive sebum production, impaired skin hydration, enlarged pores, and persistent lesions. Chemical peeling is a well-established procedure in cosmetic dermatology, while microne...

  • Article
  • Open Access
432 Views
13 Pages

Development, Tolerability and In Vitro Effectiveness of a Natural Cosmetic Formulation for Mosquito Bites

  • Ketty Gianesin,
  • Elisa Caracciolo,
  • Paolo Lucchese,
  • Emilio Baixauli and
  • Justyna M. Meissner

27 January 2026

Skin irritation and itching, often intense, are common consequences of mosquito bites. Interest in cosmetics formulated with natural ingredients has markedly increased among consumers, perceiving them as healthier, safer and more sustainable. We deve...

  • Article
  • Open Access
458 Views
15 Pages

Evaluation of Cacumen Platycladi Extract for Hair Loss Prevention: Mechanisms, Efficacy, and Clinical Application

  • Xue-Dong Bai,
  • Yu-Chen Liu,
  • Hong-Yun Zhao,
  • Yi-Zhou Luo,
  • Li-Jun Xu and
  • Feng Luo

26 January 2026

Hair loss is a prevalent condition with various causes, and effective treatments are in high demand. Cacumen Platycladi (Platycladus orientalis leaves), a traditional Chinese medicine, has been historically used to prevent hair loss. This study aimed...

  • Article
  • Open Access
277 Views
19 Pages

Personalized Dermato-Cosmetology: A Case Study on Biometric Skin Improvements After 28 Days of Bespoke Cosmetic

  • Magdalena Bîrsan,
  • Ana-Caterina Cristofor,
  • Alin-Viorel Focșa,
  • Cătălin-Dragoș Ghica,
  • Șadiye-Ioana Scripcariu,
  • Carmen-Valerica Ripa,
  • Robert-Alexandru Vlad,
  • Paula Antonoaea,
  • Cezara Pintea and
  • Adriana Ciurba
  • + 4 authors

26 January 2026

Objective: This study aimed to design and clinically evaluate a bespoke cosmetic formulation tailored to individual skin characteristics and user preferences, focusing on hydration and barrier recovery in mature, therapy-affected skin. In addition, t...

  • Article
  • Open Access
512 Views
16 Pages

Pycnogenol® Mitigates Oxidative Stress and Improves Skin Defenses Against Environmental Pollutants: An Ex-Vivo Human Skin Explant Study

  • Fabrice Avaltroni,
  • Carolina Burki,
  • Franziska Weichmann,
  • Giuseppe Percoco,
  • Laurent Peno-Mazzarino and
  • Elian Lati

23 January 2026

Oxidative stress is a major factor in skin aging and various skin pathologies. Environmental pollutants exacerbate this stress by generating reactive oxygen species (ROS), disrupting the skin’s redox balance. Pycnogenol®, a French maritime...

  • Review
  • Open Access
1,054 Views
23 Pages

22 January 2026

The cosmetic industry is undergoing a deep transformation driven by rapid innovation, evolving consumer expectations, and increasing demands for sustainability. Formulators are required to design products that combine functional efficacy, stability,...

  • Article
  • Open Access
305 Views
20 Pages

Development of a Novel Peptide-Caffeic Acid Conjugate with Enhanced Anti-Photoaging Properties: Efficacy, Transdermal Permeation, and Stability

  • Lijuan Liu,
  • Lu Zhang,
  • Zijian Liu,
  • Chelsea Tan,
  • Eric Lam,
  • Matthew C. Ehrman,
  • Choon-Peng Chng,
  • Shikhar Gupta,
  • Changjin Huang and
  • Wenfeng Ding
  • + 1 author

21 January 2026

Caffeoyl hexapeptide-9 (CH-9) is a novel cosmetic peptide designed by conjugating hexapeptide-9 (H-9), a known collagen-mimetic peptide with established skin anti-aging activity, with caffeic acid (CA) via an amide bond, leveraging peptide-drug conju...

  • Article
  • Open Access
349 Views
20 Pages

Phytocosmetic Water-in-Oil Emulsions with Plant Oils: Physicochemical, Rheological and Photoprotective Evaluation

  • Nebojša Pavlović,
  • Katarina Žabić,
  • Dragana Zaklan,
  • Jovana Milutinov,
  • Dejan Ćirin and
  • Veljko Krstonošić

18 January 2026

Plant oils are increasingly explored as sustainable functional ingredients in topical emulsions due to their emollient properties and reported photoprotective potential. This study aimed to formulate physically stable W/O emulsions containing selecte...

  • Article
  • Open Access
493 Views
23 Pages

Liquid Extract from the Bark of Magnolia officinalis Rejuvenates Skin Aging Through Mitochondrial ROS Reduction

  • Yun Haeng Lee,
  • Eun Young Jeong,
  • Ye Hyang Kim,
  • Sekyung Oh,
  • Jee Hee Yoon,
  • Ji Ho Park,
  • Yoo Jin Lee,
  • Duyeol Kim,
  • Byeonghyeon So and
  • Joon Tae Park
  • + 5 authors

15 January 2026

Reactive oxygen species (ROS) are a major cause of skin aging, leading to oxidation and cleavage of collagen that supports skin structure. Previous studies have demonstrated that Magnolia officinalis var. officinalis (M. officinalis) dry extract redu...

  • Article
  • Open Access
403 Views
22 Pages

Dissolvable Face Mask with Liposomal Licorice Extract and Kojic Acid: An Innovative Approach for Skin Brightening

  • Theerada Taesotikul,
  • Supusson Pengnam,
  • Thapakorn Charoenying,
  • Boonnada Pamornpathomkul,
  • Prin Chaksmithanont,
  • Prasopchai Patrojanasophon and
  • Chaiyakarn Pornpitchanarong

14 January 2026

This study developed a biodegradable dissolvable face mask incorporating liposomal kojic acid (KA) and licochalcone A from licorice extract (LE) to enhance skin delivery and performance. Liposomes were prepared by thin-film hydration method. The film...

  • Article
  • Open Access
526 Views
14 Pages

Efficacy and Safety of a Cannabinoid-Based Topical Cream in Atopic-Prone Skin: A Prospective Clinical Study

  • Maite Bilbatua,
  • Ander Pino,
  • Josune Torrecilla,
  • Leire Arana-Pascual,
  • Saioa Mateos,
  • José María Alonso,
  • María Moneo-Sánchez and
  • Raúl Pérez

14 January 2026

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disorder. Revodiol Calming Cream® (RCC) is a novel dermocosmetic product containing cannabidiol (CBD) and Annona cherimola fruit extract, designed for the management of atopic-pron...

  • Review
  • Open Access
1,038 Views
31 Pages

14 January 2026

Hair loss disorders, particularly androgenetic alopecia (AGA), are common conditions that carry significant psychosocial impact. Current standard therapies, including minoxidil, finasteride, and hair transplantation, primarily slow progression or re-...

  • Article
  • Open Access
423 Views
15 Pages

Physicochemical Properties of Two Poly-L-Lactic Acid Injectable Implants: Potential Impact on Their Biological Properties

  • Luiz Avelar,
  • Alessandra Haddad,
  • Sabrina G. Fabi,
  • Michael Somenek,
  • Katie Beleznay,
  • Shino Bay Aguilera,
  • Kathryn Taylor-Barnes,
  • Cheri Mao,
  • Åke Öhrlund and
  • Daniel Bråsäter
  • + 4 authors

13 January 2026

This study evaluated the thermal properties, crystallinity, particle size, morphology, and in vivo local inflammation and persistence of two poly-L-lactic acid (PLLA) injectable implants, Sculptra® (PLLA-SCA) and GANA V® (PLLA-GA). PLLA-SCA a...

  • Article
  • Open Access
438 Views
14 Pages

13 January 2026

Surfactants are commonly employed in cleaning, cosmetic, and pharmaceutical formulations due to their ability to lower surface tension and facilitate the formation of emulsions, foams, and dispersions. Recent research highlights the advantages of syn...

  • Article
  • Open Access
421 Views
16 Pages

Regenerative and Dermal Wound Healing Activities of Bioactive Octapeptide

  • Shan Lakmal Edirisinghe,
  • Chamilani Nikapitiya and
  • Mahanama De Zoysa

13 January 2026

Cosmeceutical peptides (CPs), which modulate various biological activities, including skin regeneration and wound healing, have emerged as promising agents in skincare. In this study, we investigated the regenerative and wound healing potential of a...

  • Article
  • Open Access
507 Views
16 Pages

Unveiling the Potential of Plant-Derived Exosome-like Extracellular Vesicles from Phalaenopsis aphrodite as Skin-Conditioning Ingredients in Cosmetic Applications

  • Kai-An Chuang,
  • Kuei-Chang Li,
  • Hsin-Jan Yao,
  • Pei-Yin Tsai,
  • I Huang Lu,
  • Chu Hung Lin,
  • Hira Umbreen,
  • Chi-Chien Lin and
  • I-Hong Pan

12 January 2026

Plant-derived exosome-like extracellular vesicles (PELVs) have recently emerged as novel bioactive materials. Although members of the Orchidaceae family have been reported to possess various biological activities and are widely used as cosmetic ingre...

  • Article
  • Open Access
339 Views
16 Pages

12 January 2026

Melasma management is challenged by heterogeneity in patient presentation, particularly among individuals with darker skin tones. This study applied k-means clustering, an unsupervised machine learning algorithm that partitions data into k distinct c...

  • Article
  • Open Access
499 Views
16 Pages

Performance of Platycladus orientalis Leaves Yeast Fermented Solution on Human Dermal Papilla Cells

  • Kuan Chang,
  • Lingjuan Liu,
  • Xianqi Chen,
  • Jinhua Li,
  • Timson Chen,
  • Zhizhen Li,
  • Ya Chen,
  • Ling Ma and
  • Jing Wang

12 January 2026

Platycladus orientalis exhibits significant potential as an antioxidant, anti-inflammatory, and hair growth-promoting ingredient, while the low bioavailability of raw Platycladus orientalis leaves extracts limits their further application. In this st...

  • Commentary
  • Open Access
914 Views
9 Pages

The pursuit of fine chemicals from natural sources is advancing rapidly, driven by a growing demand for safe, sustainable, and high-performance ingredients in cosmetic and pharmaceutical formulations. Emerging extraction and biotransformation technol...

  • Article
  • Open Access
591 Views
18 Pages

Ecofriendly Biosurfactant-Containing Solid Shampoo Formulation for Pets

  • Ana Paula B. Cavalcanti,
  • Gleice P. de Araújo,
  • Fabíola Carolina G. de Almeida,
  • Káren Gercyane O. Bezerra,
  • Maria da Glória C. da Silva,
  • Alessandra Sarubbo,
  • Rita de Cássia F. Soares da Silva and
  • Leonie A. Sarubbo

The growing demand for sustainable cosmetic products and the rapid expansion of the pet care market have driven the search for environmentally friendly, safe, and effective alternatives to conventional formulations. In this study, an ecofriendly soli...

  • Article
  • Open Access
606 Views
25 Pages

Development of an Epidermal Growth Factor (EGF) Loaded Elastosome Formulation for Enhanced Skin Penetration and Anti-Aging Effects

  • Seul Gi Heo,
  • Won Kyu Hong,
  • Eun Mi Kim,
  • Min Soo Kim,
  • Si Young Song,
  • Su Mi Choi,
  • Jun Hyeong Park,
  • Ji Hye Kim and
  • Gwang Seong Choi

Achieving optimal skin penetration with bioactive cosmetic ingredients, such as epidermal growth factor (EGF), presents ongoing challenges. This study introduces a novel elastosome-based EGF delivery system co-loading dexpanthenol, which achieves sup...

  • Article
  • Open Access
356 Views
14 Pages

Adipose-derived mesenchymal stem cells (AD-MSCs) secrete various growth factors that activate skin cells. This study investigated the effects of crude extracts and isolated compounds, hitorin A and hitorin B, from Chloranthus quadrifolius on AD-MSCs....

  • Review
  • Open Access
678 Views
17 Pages

Ceramides are central to stratum corneum barrier organization and hydration. Beyond topical replenishment, ceramide-stimulating strategies increasingly aim to enhance endogenous ceramide biosynthesis, processing, and homeostatic remodeling in coordin...

  • Review
  • Open Access
925 Views
26 Pages

29 December 2025

Post-oncologic skin is subject to multiple structural and functional impairments following chemotherapy and radiotherapy, including delayed epidermal turnover, compromised barrier integrity, and mitochondrial dysfunction. These changes can lead to pe...

  • Article
  • Open Access
804 Views
22 Pages

Concentration-Dependent Rheological and Sensory Effects of Walnut Leaf Extract in Cosmetic Emulsion Creams

  • Miljan Adamovic,
  • Ana Adamovic,
  • Ana Barjaktarevic,
  • Marina Kostic,
  • Olivera Kostic,
  • Danijela Pecarski,
  • Marijana Andjic,
  • Jovana Dimitrijevic,
  • Jelena Zivkovic and
  • Marina Tomovic

26 December 2025

Background/Objectives: Understanding how plant-derived extracts influence the rheological and sensory behavior of emulsions is crucial for developing stable and consumer-appealing formulations. Although walnut leaf extract (Juglans regia L.) is recog...

  • Article
  • Open Access
1,576 Views
11 Pages

Artificial Intelligence in Cosmetic Dermatology with Regard to Laser Treatments: A Comparative Analysis of AI and Dermatologists’ Decision-Making

  • Alexandra Junge,
  • Ali Mokhtari,
  • Simone Cazzaniga,
  • Ashraf Badawi,
  • Flurin Brand,
  • Simone Böll,
  • Laurence Feldmeyer,
  • Cindy Franklin,
  • Hans-Joachim Laubach and
  • Seyed Morteza Seyed Jafari
  • + 10 authors

26 December 2025

Introduction: Artificial intelligence (AI) has developed into an increasingly important tool in dermatology. While new technologies integrated within laser devices are emerging, there is a lack of data on the applicability of publicly available AI mo...

  • Article
  • Open Access
1 Citations
833 Views
17 Pages

25 December 2025

Skin hydration is a key indicator of skin health and stratum corneum (SC) integrity, yet its relationship with multi-dimensional physiological parameters remains incompletely understood. This study aimed to investigate the association between facial...

  • Article
  • Open Access
929 Views
14 Pages

Protective and Restorative Effects of a Bio-Based Crosslinking Complex on Chemically Damaged Hair

  • Flavio B. Camargo Junior,
  • Alessandra M. Goshiyama,
  • Gessica F. D. Oliveira,
  • Marcos R. Rossan,
  • Cleverson R. Princival,
  • Edson Katekawa,
  • Wagner Magalhães,
  • Rafaela de Almeida Zito,
  • Letícia Kakuda and
  • Patrícia Maria Berardo Gonçalves Maia Campos

24 December 2025

This study addresses the growing consumer demand for effective and sustainable hair care solutions by evaluating a novel bioactive crosslink repair complex designed to restore chemically damaged hair. The complex comprises itaconic acid, arginine, D-...

  • Article
  • Open Access
1,423 Views
13 Pages

Prospective Multicentre Real-World Study of a Bioregenerative Combination Therapy with Polynucleotide High-Purification Technology (PN HPT™) and Hyaluronic Acid for Moderate-to-Severe Atrophic Facial Acne Scars

  • Ting Song Lim,
  • Chong Ian,
  • Nurul Ain Abdullah,
  • Tristan Tan,
  • Kuok Tjun Ong,
  • Leda Moro,
  • Maria Tomat,
  • Carmen De Luca,
  • Simona Piscopo and
  • Carlotta Bortoletti
  • + 1 author

22 December 2025

Background: Facial atrophic acne scars have a significant impact on patients’ psychosocial well-being and remain a therapeutic challenge. Existing treatments options are frequently limited by modest efficacy and adverse effects. The combination...

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Cosmetics - ISSN 2079-9284